id subject predicate object category relation description has_attribute source uuid:56f4700a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:56f4a9b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:56f4d89c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:56f501fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets GPCR (Prostaglandin E2 receptor EP1 subtype) DrugCentral uuid:56f52b58-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.707']} DrugCentral uuid:56f55a06-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (5-hydroxytryptamine receptor 3A) DrugCentral uuid:56f58364-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:56f5b190-6b31-11ec-b3df-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:4 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobupivacaine targets Ion channel (Potassium voltage-gated channel subfamily A member 5) DrugCentral uuid:56f5df6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:56f5df6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:56f61856-6b31-11ec-b3df-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is blocker of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:56f646b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:56f674d6-6b31-11ec-b3df-0242ac110002 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:56f6a3c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:56f6d20a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:56f70054-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:6 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 (S)-nitrendipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:56f72a3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:13 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levdobutamine is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:56f7536a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:56f78150-6b31-11ec-b3df-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:56f7af0e-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:56f7dea2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48760 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin targets Enzyme (Folylpoly-gamma-glutamate synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:56f80c92-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:21 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopterin is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:56f83a64-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:24 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutanoic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:56f86908-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:24 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutanoic acid targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:56f896d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:24 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutanoic acid targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:56f8c484-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:24 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutanoic acid targets Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:56f8f38c-6b31-11ec-b3df-0242ac110002 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:25 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacitidine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:56f921ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:25 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacitidine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:56f94aa8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:56f97398-6b31-11ec-b3df-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:56f99d96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96J66 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil targets Transporter (ATP-binding cassette sub-family C member 11) DrugCentral uuid:56f9c6fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:56f9f4b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8F0 biolink:molecularly_interacts_with DrugCentral:26 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorouracil targets Enzyme (Uracil phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:56fa2298-6b31-11ec-b3df-0242ac110002 UniProtKB:O26232 biolink:molecularly_interacts_with DrugCentral:27 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azaribine targets Enzyme (Orotidine 5'-phosphate decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:56fa5114-6b31-11ec-b3df-0242ac110002 UniProtKB:P03962 biolink:molecularly_interacts_with DrugCentral:27 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azaribine targets Enzyme (Orotidine 5'-phosphate decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:56fa7f86-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:56faad44-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:56fadb70-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:56fb092e-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:56fb3700-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:30 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxsalen targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:56fb6496-6b31-11ec-b3df-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:34 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abacavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.276']} DrugCentral uuid:56fb9448-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:34 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abacavir is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:56fbc1f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:34 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abacavir targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:56fbf0fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:35 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abarelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.49']} DrugCentral uuid:56fc2822-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:56fc2822-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:56fc2822-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:56fc8218-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:56fc8218-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:56fc8218-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:56fc8218-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:56fc8218-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:56fc8218-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:56fc8218-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:38 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acamprosate is antagonist of Ion channel (Glutamate [NMDA] receptor) DrugCentral uuid:56fcf25c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose is inhibitor of Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.697']} DrugCentral uuid:56fd2010-6b31-11ec-b3df-0242ac110002 UniProtKB:P04746 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose is inhibitor of Enzyme (Pancreatic alpha-amylase) DrugCentral uuid:56fd4a54-6b31-11ec-b3df-0242ac110002 UniProtKB:P04745 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Alpha-amylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:56fd783a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:56fda5da-6b31-11ec-b3df-0242ac110002 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:56fdd384-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:56fe01f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P94451 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Alpha-amylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:56fe2fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:P53051 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Oligo-1,6-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:56fe5d72-6b31-11ec-b3df-0242ac110002 UniProtKB:P00690 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Pancreatic alpha-amylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:56fe8b94-6b31-11ec-b3df-0242ac110002 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:39 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acarbose targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.609']} DrugCentral uuid:56feb970-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:40 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acebutolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:56fee724-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:40 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acebutolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:56ff14d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:40 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acebutolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:56ff4444-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:43 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclofenac targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:56ff71ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:43 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclofenac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:56ff9fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:43 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclofenac targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.227']} DrugCentral uuid:56ffce32-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:43 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:56fff722-6b31-11ec-b3df-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:44 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acediasulfone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:570024cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4Z710 biolink:molecularly_interacts_with DrugCentral:44 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acediasulfone targets Unclassified (Dihydropteroate synthetase, putative) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:570052e4-6b31-11ec-b3df-0242ac110002 UniProtKB:A0A113T0T6 biolink:molecularly_interacts_with DrugCentral:44 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acediasulfone targets Unclassified (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:570080b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:47 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acemetacin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:5700a9a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:47 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acemetacin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:5700d28c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:47 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acemetacin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5701025c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6TEK4 biolink:molecularly_interacts_with DrugCentral:48 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acenocoumarol is inhibitor of Unclassified (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:57013006-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:48 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acenocoumarol is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.114']} DrugCentral uuid:57015dba-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:49 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acefylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.56']} DrugCentral uuid:57018d4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:50 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceprometazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5701b634-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:5701e3d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol is opener of Ion channel (Transient receptor potential cation channel subfamily V member 1) DrugCentral uuid:57020c92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:570235dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:570263a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:570292c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:5702c114-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:5702f18e-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:57031f38-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:57034d1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:57037b4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:5703a908-6b31-11ec-b3df-0242ac110002 UniProtKB:P20292 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Cytosolic other (Arachidonate 5-lipoxygenase-activating protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:5703d694-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.547']} DrugCentral uuid:57040484-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:57043238-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:57045ff6-6b31-11ec-b3df-0242ac110002 UniProtKB:P02144 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol targets Unclassified (Myoglobin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:57048d8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:52 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paracetamol is agonist of GPCR (Cannabinoid receptor 1) DrugCentral uuid:5704ba8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:54 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetanilide targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5704ec14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9VTU8 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2, isoform A; LD26647p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:57051b80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9V396 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 1; GH09688p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:570549c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:57057792-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5705a564-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5705d386-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:57060162-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:57063038-6b31-11ec-b3df-0242ac110002 UniProtKB:P29972 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Transporter (Aquaporin-1) DrugCentral uuid:570658f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:57068a2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.27']} DrugCentral uuid:5706b8fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5706e69a-6b31-11ec-b3df-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:570714d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:57074270-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:570770e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:57079e96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5707ccae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5707fa58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERQ8 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:57082942-6b31-11ec-b3df-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:57085a0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:570889b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:5708b772-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:5708e594-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5709135c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:57094110-6b31-11ec-b3df-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:57096ece-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:57099cfa-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5709cab8-6b31-11ec-b3df-0242ac110002 UniProtKB:P29029 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Endochitinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5709f858-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.13']} DrugCentral uuid:570a286e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:570a57e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:570a85ac-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:570ab40a-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:570ae2d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:570b10c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:570b3e98-6b31-11ec-b3df-0242ac110002 UniProtKB:P00921 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:570b9b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:570b9b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:570b9b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:570b9b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:570b9b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:570b9b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:570b9b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:570b9b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:570b9b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:570b9b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:570b9b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:570b9b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:570c76f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:570c76f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:570c76f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:570c76f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:570cd212-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:570cd212-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:570d0d4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P46510 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:570d3b76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3SZX4 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.08']} DrugCentral uuid:570d6916-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.56']} DrugCentral uuid:570d96c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HVB9 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:570dc64a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.37']} DrugCentral uuid:570df624-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:570e2496-6b31-11ec-b3df-0242ac110002 UniProtKB:O75493 biolink:molecularly_interacts_with DrugCentral:56 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetazolamide targets Enzyme (Carbonic anhydrase-related protein 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:570e56b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:57 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohexamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.639']} DrugCentral uuid:570e56b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:57 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohexamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.639']} DrugCentral uuid:570e926e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:570ec8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03284 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid is inhibitor of Enzyme (Bacterial urease) DrugCentral uuid:570ec8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03284 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid is inhibitor of Enzyme (Bacterial urease) DrugCentral uuid:570ec8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03284 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid is inhibitor of Enzyme (Bacterial urease) DrugCentral uuid:570f094c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07374 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid targets Enzyme (Urease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:570f36e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0PXQ5 biolink:molecularly_interacts_with DrugCentral:58 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetohydroxamic acid targets Enzyme (Urease subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:570f6482-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:59 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetophenazine is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:570f8d54-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:59 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetophenazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:570fbf4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:570fef60-6b31-11ec-b3df-0242ac110002 UniProtKB:P08473 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril is inhibitor of Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:57101e54-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:57104c62-6b31-11ec-b3df-0242ac110002 UniProtKB:P07861 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:571079e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08049 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5710a766-6b31-11ec-b3df-0242ac110002 UniProtKB:P19621 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:5710d542-6b31-11ec-b3df-0242ac110002 UniProtKB:P42892 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Endothelin-converting enzyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:571102ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P00800 biolink:molecularly_interacts_with DrugCentral:60 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racecadotril targets Enzyme (Thermolysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5711306e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23141 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Liver carboxylesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:57115df0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14061 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Estradiol 17-beta-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:57118fc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P37059 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Estradiol 17-beta-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5711c10a-6b31-11ec-b3df-0242ac110002 UniProtKB:P80365 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5711ee8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:57121ca4-6b31-11ec-b3df-0242ac110002 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:62 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetoxolone targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:57124b3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:571278ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5712a6f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5712d46e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5713020e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:57132fa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:57136014-6b31-11ec-b3df-0242ac110002 UniProtKB:P58154 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Unclassified (Acetylcholine-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:57138db4-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:5713bb4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:5713edcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5713edcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:57142d32-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:57142d32-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:57146cca-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:57146cca-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5714ac9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:5714ac9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:5714ecc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:5714ecc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:57152fe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:57152fe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:57157d2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:57157d2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:57157d2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:57157d2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:57157d2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5715e24e-6b31-11ec-b3df-0242ac110002 UniProtKB:H6TY12 biolink:molecularly_interacts_with DrugCentral:65 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcholine targets Ion channel (Nicotinic acetylcholine receptor alpha8 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:57160f9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P99999 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine targets Enzyme (Cytochrome c) DrugCentral uuid:5716385c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine targets Secreted (Vascular endothelial growth factor A) DrugCentral uuid:5716617e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04179 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine targets Enzyme (Superoxide dismutase [Mn], mitochondrial) DrugCentral uuid:57168a46-6b31-11ec-b3df-0242ac110002 UniProtKB:P48637 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine is modulator of Enzyme (Glutathione synthetase) DrugCentral uuid:5716b46c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPY5 biolink:molecularly_interacts_with DrugCentral:66 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylcysteine is modulator of Transporter (Cystine/glutamate transporter) DrugCentral uuid:5716fe54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:5716fe54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:5716fe54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:5716fe54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:5716fe54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:5716fe54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:5716fe54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:5716fe54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:67 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetyldigitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:57177906-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:73 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acepromazine is antagonist of GPCR (D(1A) dopamine receptor) DrugCentral uuid:5717a23c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:73 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acepromazine is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:5717cafa-6b31-11ec-b3df-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:73 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acepromazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5717f85e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5718266c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:571853ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P60045 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Acidic phospholipase A2 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:57188184-6b31-11ec-b3df-0242ac110002 UniProtKB:P19440 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Gamma-glutamyltranspeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5718af10-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5718decc-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:57190c80-6b31-11ec-b3df-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:57193a16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid is blocker of Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:57196824-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:74 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylsalicylic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:571996f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:76 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acipimox is agonist of GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5719c47c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:78 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acitretin is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) DrugCentral uuid:5719ed44-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:78 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acitretin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:571a1b48-6b31-11ec-b3df-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:78 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acitretin is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) DrugCentral uuid:571a441a-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:78 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acitretin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:571a71a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.152']} DrugCentral uuid:571aa18a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:571acf0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin is inhibitor of Enzyme (DNA topoisomerase 1) DrugCentral uuid:571afc3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin is inhibitor of Enzyme (DNA topoisomerase II) DrugCentral uuid:571afc3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:80 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclarubicin is inhibitor of Enzyme (DNA topoisomerase II) DrugCentral uuid:571b4284-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:571b4284-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:571b4284-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:571b4284-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:571b4284-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:81 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclatonium is agonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:571b99fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:82 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acrivastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:571bc2d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:82 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acrivastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:571bf18e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:82 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acrivastine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:571c1f1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.04']} DrugCentral uuid:571c4ca6-6b31-11ec-b3df-0242ac110002 UniProtKB:P09250 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir targets Kinase (Thymidine kinase) DrugCentral uuid:571c7802-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WP01 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.9']} DrugCentral uuid:571ca5b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.04']} DrugCentral uuid:571cd4d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:571cfd9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P09252 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:571d26da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir is inhibitor of Kinase (Thymidine kinase) DrugCentral uuid:571d4fd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04407 biolink:molecularly_interacts_with DrugCentral:85 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acyclovir is inhibitor of Kinase (Thymidine kinase) DrugCentral uuid:571d7892-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:87 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adapalene targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:571da66e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:87 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adapalene targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:571dd42c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:87 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adapalene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:571e02ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:87 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adapalene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:571e30b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:88 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adefovir dipivoxil is inhibitor of Polyprotein (Protein P) DrugCentral uuid:571e5ba4-6b31-11ec-b3df-0242ac110002 UniProtKB:P54098 biolink:molecularly_interacts_with DrugCentral:88 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adefovir dipivoxil targets Enzyme (DNA polymerase subunit gamma-1) DrugCentral uuid:571e8480-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:88 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adefovir dipivoxil targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:571eb1f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:571eecb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:571eecb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:571eecb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:571eecb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:89 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenine targets Kinase (Phosphatidylinositol 4-kinase, PI4K) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:571f4302-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:571f70f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.509']} DrugCentral uuid:571f9e9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:571fcc32-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is agonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:571ff9d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P55263 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (Adenosine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:57202a9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00813 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.602']} DrugCentral uuid:57205882-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.29']} DrugCentral uuid:57208622-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5720b44e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5720e1f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9TVW2 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (Adenosine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:57210fb6-6b31-11ec-b3df-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:57213d4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23526 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Enzyme (Adenosylhomocysteinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.796']} DrugCentral uuid:57216fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:57216fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5721ab10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BTU6 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is inhibitor of Kinase (Phosphatidylinositol 4-kinase type 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5721d8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCG2 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine is inhibitor of Kinase (Phosphatidylinositol 4-kinase type 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:57220aba-6b31-11ec-b3df-0242ac110002 UniProtKB:P04406 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Enzyme (Glyceraldehyde-3-phosphate dehydrogenase liver) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5722467e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5722467e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5722467e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5722467e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31322 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Kinase (cAMP-dependent protein kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:57229dcc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TEK3 biolink:molecularly_interacts_with DrugCentral:90 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine targets Enzyme (Histone-lysine N-methyltransferase, H3 lysine-79 specific) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5722cb76-6b31-11ec-b3df-0242ac110002 UniProtKB:P49652 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5722f8f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P51575 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Ion channel (P2X purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:57232788-6b31-11ec-b3df-0242ac110002 UniProtKB:P51582 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:57235528-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:572382dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P47900 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5723b1b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5723e3ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96G91 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets GPCR (P2Y purinoceptor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:572411fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:57243f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BPV8 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of GPCR (P2Y purinoceptor 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:57246dc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41148 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Membrane other (Endoplasmin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:57249b54-6b31-11ec-b3df-0242ac110002 UniProtKB:P49137 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (MAP kinase-activated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5724c8fe-6b31-11ec-b3df-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5724f734-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99571 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Ion channel (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:572524b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13304 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:57255242-6b31-11ec-b3df-0242ac110002 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.836']} DrugCentral uuid:5725800a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12931 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Unclassified (Heat shock protein 75 kDa, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5725aec2-6b31-11ec-b3df-0242ac110002 UniProtKB:P29410 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (Adenylate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.05']} DrugCentral uuid:5725dc76-6b31-11ec-b3df-0242ac110002 UniProtKB:P11142 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Unclassified (Heat shock cognate 71 kDa protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:572609e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMV8 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Unclassified (Heat shock 70 kDa protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5726381a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7TN37 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:572666be-6b31-11ec-b3df-0242ac110002 UniProtKB:P49653 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5726947c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJX6 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5726c212-6b31-11ec-b3df-0242ac110002 UniProtKB:O35811 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5726f00c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:57271dac-6b31-11ec-b3df-0242ac110002 UniProtKB:P51579 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:57274b24-6b31-11ec-b3df-0242ac110002 UniProtKB:P51578 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:572779fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate is agonist of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5727a79a-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:91 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine triphosphate targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5727d53a-6b31-11ec-b3df-0242ac110002 UniProtKB:P09467 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Fructose-1,6-bisphosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:57280334-6b31-11ec-b3df-0242ac110002 UniProtKB:P00636 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Fructose-1,6-bisphosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:572830b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:57285e4c-6b31-11ec-b3df-0242ac110002 UniProtKB:O94759 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Ion channel (Transient receptor potential cation channel subfamily M member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:57288bec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5728ba18-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:5728ebfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:5728ebfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:57292764-6b31-11ec-b3df-0242ac110002 UniProtKB:P00338 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (L-lactate dehydrogenase A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.19']} DrugCentral uuid:5729581a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A9J4 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (Ketopantoate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.2']} DrugCentral uuid:572985d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P29410 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Kinase (Adenylate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5729b382-6b31-11ec-b3df-0242ac110002 UniProtKB:O43598 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (2'-deoxynucleoside 5'-phosphate N-hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:5729e23a-6b31-11ec-b3df-0242ac110002 UniProtKB:O35820 biolink:molecularly_interacts_with DrugCentral:92 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adenosine phosphate targets Enzyme (2'-deoxynucleoside 5'-phosphate N-hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:572a0fda-6b31-11ec-b3df-0242ac110002 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam targets Transporter (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572a70ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:93 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adinazolam is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:572b2988-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:572b6812-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:572b6812-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:572b6812-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:572b6812-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:572b6812-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:94 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adiphenine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:572bcbf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:572bf994-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:572c2bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:572c2bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:572c6ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:572c6ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:572c6ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:572cb8ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:572ce836-6b31-11ec-b3df-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:572d17ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:99 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 agomelatine is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:572d4588-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ajmaline is inhibitor of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:572d6e50-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ajmaline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:572d9d4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ajmaline is inhibitor of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:572dcb34-6b31-11ec-b3df-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ajmaline is inhibitor of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:572df8d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:101 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alacepril is inhibitor of Enzyme (Angiotensin-converting enzyme) DrugCentral uuid:572e267e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alatrofloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:572e267e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alatrofloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:572e5f90-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alatrofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:572e5f90-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alatrofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:572e9410-6b31-11ec-b3df-0242ac110002 UniProtKB:P50719 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole targets Structural (Tubulin alpha chain) DrugCentral uuid:572ec7dc-6b31-11ec-b3df-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:572ec7dc-6b31-11ec-b3df-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:572ec7dc-6b31-11ec-b3df-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:572f2862-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:572f2862-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:572f2862-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:572f2862-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:572f2862-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:572f2862-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:572f2862-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:572f9bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P50719 biolink:molecularly_interacts_with DrugCentral:104 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albendazole sulfoxide targets Structural (Tubulin alpha chain) DrugCentral uuid:572fc48e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salbutamol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.613']} DrugCentral uuid:572ff2ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salbutamol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:5730206e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salbutamol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.94']} DrugCentral uuid:57304e22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salbutamol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:57307bcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:5730a642-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alclofenac targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:5730cf14-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:5730fcb4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.9']} DrugCentral uuid:57312acc-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:57315862-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5731860c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.721']} DrugCentral uuid:5731b51e-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.959']} DrugCentral uuid:5731e30e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:57321900-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Acetylcholine receptor) DrugCentral uuid:57321900-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Acetylcholine receptor) DrugCentral uuid:57321900-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Acetylcholine receptor) DrugCentral uuid:57325f0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.347']} DrugCentral uuid:57325f0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.347']} DrugCentral uuid:57329aec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldosterone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5732c846-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldosterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5732f5f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldosterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:573323ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldosterone targets Transcription factor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.37']} DrugCentral uuid:57335176-6b31-11ec-b3df-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:57337f16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5733acfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid targets Enzyme (Protein farnesyltransferase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:5733da74-6b31-11ec-b3df-0242ac110002 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:573407ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alendronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:57343690-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NR96 biolink:molecularly_interacts_with DrugCentral:113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alexidine targets Membrane receptor (Toll-like receptor 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:57346426-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alexidine targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:573491c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q932Y6 biolink:molecularly_interacts_with DrugCentral:113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alexidine targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5734bf48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WUK0 biolink:molecularly_interacts_with DrugCentral:113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alexidine is inhibitor of Enzyme (Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.97']} DrugCentral uuid:5734ed42-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:57351a9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.951']} DrugCentral uuid:57354828-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:5735760e-6b31-11ec-b3df-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5735b038-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:5735b038-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:5735b038-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:5735b038-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:573608f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:573636b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:573665f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:57369386-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:5736c176-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:5736ef02-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:57371ca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfuzosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:57374a6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.61']} DrugCentral uuid:573777f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.678']} DrugCentral uuid:5737a596-6b31-11ec-b3df-0242ac110002 UniProtKB:P00797 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren is inhibitor of Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5737d304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9TSZ1 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:573804be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6DLS0 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5738363c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08424 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:573864ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P06281 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.35']} DrugCentral uuid:57389262-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7M3D2 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5738bfda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:5738ed5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6DLW5 biolink:molecularly_interacts_with DrugCentral:119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aliskiren targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:57391b4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alizapride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:573948ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alizapride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:573976aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alizapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5739a440-6b31-11ec-b3df-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol is inhibitor of Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5739d398-6b31-11ec-b3df-0242ac110002 UniProtKB:P00492 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol targets Enzyme (Hypoxanthine-guanine phosphoribosyltransferase) DrugCentral uuid:5739fc60-6b31-11ec-b3df-0242ac110002 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:573a2a1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22985 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:573a591c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9FBI2 biolink:molecularly_interacts_with DrugCentral:124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 allopurinol targets Unclassified (Shiga toxin subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:573a869e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 almotriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:573ab448-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 almotriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:573ae1de-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 almotriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:573b0fd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alosetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:573b3d6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alosetron targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:573b6b40-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alosetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:573b9a7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alosetron targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.218']} DrugCentral uuid:573bc7e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfacalcidol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:573bf574-6b31-11ec-b3df-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfacalcidol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:573c1e28-6b31-11ec-b3df-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Transporter (Sodium- and chloride-dependent GABA transporter 1) DrugCentral uuid:573c4fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:573c4fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:573c4fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573cd836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:573ddfe2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:573ddfe2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:573ddfe2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alfaxalone targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:573e28da-6b31-11ec-b3df-0242ac110002 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Transporter (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:573e5684-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:573e8406-6b31-11ec-b3df-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573ef0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:573fec60-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:574019d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem targets Unclassified (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:57404782-6b31-11ec-b3df-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpidem is partial agonist of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) DrugCentral uuid:574070a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.85']} DrugCentral uuid:57409e1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.457']} DrugCentral uuid:5740cc3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5740f9ac-6b31-11ec-b3df-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.61']} DrugCentral uuid:57413480-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:57413480-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:57413480-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:57418566-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:57418566-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:57418566-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:5741d87c-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.161']} DrugCentral uuid:5741d87c-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.161']} DrugCentral uuid:5741d87c-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.161']} DrugCentral uuid:574229a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:574229a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:574229a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:57427282-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:57429ffa-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:5742cd7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.86']} DrugCentral uuid:5742fffe-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:57432dc6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02769 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets Enzyme (Squalene synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:57435b48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:57438942-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:5743b6ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.678']} DrugCentral uuid:5743e4a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprenolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.658']} DrugCentral uuid:574412c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5744403a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:57446d94-6b31-11ec-b3df-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:57449b0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5744cb0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5744f87c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:574525ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:574553d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:57458152-6b31-11ec-b3df-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5745aef2-6b31-11ec-b3df-0242ac110002 UniProtKB:P32240 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:5745dc92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:57460a96-6b31-11ec-b3df-0242ac110002 UniProtKB:P43114 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:57463822-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:57466586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:574695b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5746c332-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is activator of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5746f096-6b31-11ec-b3df-0242ac110002 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:57471eae-6b31-11ec-b3df-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.35']} DrugCentral uuid:57474c1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alprostadil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:57477ae8-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 altretamine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:5747a86a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alvimopan is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:5747d682-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alvimopan targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:574804ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alvimopan targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:57483244-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alvimopan targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:574861ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:57488fd2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:5748beda-6b31-11ec-b3df-0242ac110002 UniProtKB:P63231 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is inhibitor of Ion channel (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5749066a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5749066a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5749066a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5749066a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5749066a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5749066a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5749066a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:57498496-6b31-11ec-b3df-0242ac110002 UniProtKB:Q20MD5 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5749b27c-6b31-11ec-b3df-0242ac110002 UniProtKB:P05778 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5749e012-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DOF8 biolink:molecularly_interacts_with DrugCentral:144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:574a0d9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambenonium is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:574a3846-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambenonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.34']} DrugCentral uuid:574a6992-6b31-11ec-b3df-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambenonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:574a9908-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:147 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambroxol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.744']} DrugCentral uuid:574ac6f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:147 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambroxol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.254']} DrugCentral uuid:574af45c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:147 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambroxol targets Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:574b1d38-6b31-11ec-b3df-0242ac110002 UniProtKB:P04062 biolink:molecularly_interacts_with DrugCentral:147 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambroxol targets Enzyme (Glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:574b4ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amcinonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:574b7d82-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:574b7d82-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:574b7d82-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:574bce7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:574bce7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:574bce7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amidefrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:574c19d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifostine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.184']} DrugCentral uuid:574c4aaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifostine targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) DrugCentral uuid:574c735e-6b31-11ec-b3df-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amikacin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.201']} DrugCentral uuid:574ca19e-6b31-11ec-b3df-0242ac110002 UniProtKB:P37088 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Ion channel (Amiloride-sensitive sodium channel subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:574ccf20-6b31-11ec-b3df-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:574cfca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:574d2a4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.408']} DrugCentral uuid:574d5864-6b31-11ec-b3df-0242ac110002 UniProtKB:P19634 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Transporter (Sodium/hydrogen exchanger 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:574d85f0-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:574db354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16515 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is blocker of Ion channel (Acid-sensing ion channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:574de266-6b31-11ec-b3df-0242ac110002 UniProtKB:P78348 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:574e102e-6b31-11ec-b3df-0242ac110002 UniProtKB:O08590 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Enzyme (Membrane primary amine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:574e3e46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:574e751e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:574e751e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:574e751e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:574ebd80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9W6Q1 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Transporter (Sodium/hydrogen exchanger) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:574eec42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14940 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is inhibitor of Transporter (Sodium/hydrogen exchanger 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:574f1ac8-6b31-11ec-b3df-0242ac110002 UniProtKB:P26431 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride is inhibitor of Transporter (Sodium/hydrogen exchanger 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:574f4958-6b31-11ec-b3df-0242ac110002 UniProtKB:P50482 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Transporter (Sodium/hydrogen exchanger 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:574f76ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P06869 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:574fa470-6b31-11ec-b3df-0242ac110002 UniProtKB:P55926 biolink:molecularly_interacts_with DrugCentral:158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiloride targets Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:574fd33c-6b31-11ec-b3df-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:160 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoacridine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:575000be-6b31-11ec-b3df-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:160 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoacridine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:57502e54-6b31-11ec-b3df-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:160 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoacridine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:57505c76-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amineptine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:575089ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminocaproic acid is inhibitor of Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5750b75c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminocaproic acid is inhibitor of Enzyme (Tissue-type plasminogen activator) DrugCentral uuid:5750dffc-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:57510dec-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:57513b78-6b31-11ec-b3df-0242ac110002 UniProtKB:P05108 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide is inhibitor of Enzyme (Cholesterol side-chain cleavage enzyme, mitochondrial) DrugCentral uuid:57516436-6b31-11ec-b3df-0242ac110002 UniProtKB:P22443 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:575192b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00189 biolink:molecularly_interacts_with DrugCentral:164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoglutethimide targets Enzyme (Cytochrome P450 11A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5751c03e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminohippuric acid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5751edc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminohippuric acid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:57521bce-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminophenazone targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:57524482-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminophenazone targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:57526d2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminophenazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:57529aae-6b31-11ec-b3df-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminopicoline is inhibitor of Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5752c8e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoquinuride targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5752f65c-6b31-11ec-b3df-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoquinuride targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:575323de-6b31-11ec-b3df-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoquinuride targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5753521e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminoquinuride targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:575380e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5753ae58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5753dcc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.112']} DrugCentral uuid:57540aba-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:57543850-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.177']} DrugCentral uuid:575465d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:575493fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5754c1bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5754ef16-6b31-11ec-b3df-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:57551d4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:57554e84-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:57557d5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5755aaf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5755d8ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.912']} DrugCentral uuid:5756068a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.647']} DrugCentral uuid:5756340c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.989']} DrugCentral uuid:57566274-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.231']} DrugCentral uuid:5756915e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.674']} DrugCentral uuid:5756bf08-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.045']} DrugCentral uuid:5756eca8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:57571b24-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.387']} DrugCentral uuid:5757489c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.984']} DrugCentral uuid:57577628-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:5757a422-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.743']} DrugCentral uuid:5757d230-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.168']} DrugCentral uuid:5757ffd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.296']} DrugCentral uuid:57582d66-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.968']} DrugCentral uuid:57585cc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.498']} DrugCentral uuid:57588a72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.701']} DrugCentral uuid:5758b826-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.004']} DrugCentral uuid:5758e800-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.207']} DrugCentral uuid:575915fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.176']} DrugCentral uuid:57594386-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.549']} DrugCentral uuid:57597176-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:57599eee-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.284']} DrugCentral uuid:5759cc84-6b31-11ec-b3df-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.791']} DrugCentral uuid:5759fa06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14534 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:575a283c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.088']} DrugCentral uuid:575a55be-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.039']} DrugCentral uuid:575a8322-6b31-11ec-b3df-0242ac110002 UniProtKB:P37268 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Squalene synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:575ab234-6b31-11ec-b3df-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.368']} DrugCentral uuid:575ae042-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.191']} DrugCentral uuid:575b0dce-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:575b3b6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:575b6954-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.347']} DrugCentral uuid:575b96c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:575bc4c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.407']} DrugCentral uuid:575bf2e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30411 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.115']} DrugCentral uuid:575c207e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.879']} DrugCentral uuid:575c4e28-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:575c7cd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.967']} DrugCentral uuid:575cadf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.943']} DrugCentral uuid:575cdda2-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.932']} DrugCentral uuid:575d0b2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:575d391e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:575d668c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Unclassified (THAP domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:575d940e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15389 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:575dc23a-6b31-11ec-b3df-0242ac110002 UniProtKB:O75151 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Lysine-specific demethylase PHF2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:575defe4-6b31-11ec-b3df-0242ac110002 UniProtKB:P29375 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Lysine-specific demethylase 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:575e1ec4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6ZMT4 biolink:molecularly_interacts_with DrugCentral:176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amiodarone targets Enzyme (Lysine-specific demethylase 7A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:575e4c3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.953']} DrugCentral uuid:575e7afe-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.081']} DrugCentral uuid:575ea880-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:575ed60c-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.382']} DrugCentral uuid:575f0406-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:575f3188-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.758']} DrugCentral uuid:575f5eec-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.873']} DrugCentral uuid:575f8d18-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.812']} DrugCentral uuid:575fbaa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.625']} DrugCentral uuid:575fe81c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:576015a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:576045e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amisulpride is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.495']} DrugCentral uuid:57607386-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5760a0ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.051']} DrugCentral uuid:5760ceee-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.708']} DrugCentral uuid:5760fc8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.879']} DrugCentral uuid:57612a1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:57615878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:576186cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.367']} DrugCentral uuid:5761b458-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.456']} DrugCentral uuid:5761e1e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:57621222-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:57623fa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:57626d3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:57629b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:5762c8de-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5762f64c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:576323b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:57635272-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.686']} DrugCentral uuid:57637fea-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5763ad80-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5763dcce-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:57640e10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:57643d5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.83']} DrugCentral uuid:57646b44-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:576498bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5764c652-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:5764f3ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:57652200-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.585']} DrugCentral uuid:57654f64-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.066']} DrugCentral uuid:57657ce6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5765abbc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5765db96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5766092c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.252']} DrugCentral uuid:576636ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5766649e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5766920c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5766bf7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:5766edce-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.771']} DrugCentral uuid:57671b5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:576748dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:57677708-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5767a836-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5767d5cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5768034e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5768313e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:57685ed4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:57688c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:5768ba82-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5768e818-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.854']} DrugCentral uuid:57692670-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:57692670-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:57692670-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:57692670-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:57692670-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:57698da4-6b31-11ec-b3df-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptyline is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5769bb12-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amitriptylinoxide targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5769ea06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:576a1774-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:576a44ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:576a7ef8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:576a7ef8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:576a7ef8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:576a7ef8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlexanox is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:576acb88-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.646']} DrugCentral uuid:576af914-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.871']} DrugCentral uuid:576b2894-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:576b567a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:576b83ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.583']} DrugCentral uuid:576bb16a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.358']} DrugCentral uuid:576bdf64-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:576c0cf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:576c3a7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:576c68bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:576c92ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:576cbb64-6b31-11ec-b3df-0242ac110002 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:576ce8fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:576d1924-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.507']} DrugCentral uuid:576d46a6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:576d73ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:576da1e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8HY88 biolink:molecularly_interacts_with DrugCentral:183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amlodipine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:576dcf4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amodiaquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:576dfcb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P50135 biolink:molecularly_interacts_with DrugCentral:186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amodiaquine targets Enzyme (Histamine N-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:576e2b66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y251 biolink:molecularly_interacts_with DrugCentral:186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amodiaquine targets Enzyme (Heparanase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.28']} DrugCentral uuid:576e597e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amodiaquine targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:576e87d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.708']} DrugCentral uuid:576eb554-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:576ee4fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.307']} DrugCentral uuid:576f1274-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:576f3b46-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.469']} DrugCentral uuid:576f694a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:576f96f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:576fc494-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.75']} DrugCentral uuid:576ff2ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.182']} DrugCentral uuid:5770229a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:57705026-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:57707dbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5770ad32-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.593']} DrugCentral uuid:5770dde8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.734']} DrugCentral uuid:57710b6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:57713900-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.542']} DrugCentral uuid:577166dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:57719454-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.423']} DrugCentral uuid:5771c276-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.616']} DrugCentral uuid:5771f0ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.211']} DrugCentral uuid:57721e4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.336']} DrugCentral uuid:57724bce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.365']} DrugCentral uuid:57727aae-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5772aae2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:5772d97c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.842']} DrugCentral uuid:57730708-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5773350c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y345 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Transporter (Sodium- and chloride-dependent glycine transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.036']} DrugCentral uuid:5773628e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:57739006-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.45']} DrugCentral uuid:5773be50-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5773ebf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:57741968-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5774494c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5774807e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5774807e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5774807e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxapine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5774c1c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5774ef8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:57751d04-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:57754a7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:57758d48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57758d48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57758d48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57758d48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57758d48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57758d48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57758d48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amoxicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5775fbfc-6b31-11ec-b3df-0242ac110002 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amperozide targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:57762b0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amperozide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:577659c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:5776827a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.753']} DrugCentral uuid:5776affc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:5776da4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:57770312-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine is releasing agent of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.936']} DrugCentral uuid:5777309e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16568 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transcription factor (Cocaine- and amphetamine-regulated transcript protein) DrugCentral uuid:57775a1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:57778788-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:5777b514-6b31-11ec-b3df-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5777e28c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:577812a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:57784024-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5778a47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:57798f88-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:57798f88-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:57798f88-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:57798f88-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5779f090-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:5779f090-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:5779f090-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:577a39c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amfetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:577a6782-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:577a9040-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.09']} DrugCentral uuid:577abdb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin targets Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:577b055c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:577b055c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:577b055c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:577b055c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:577b055c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:577b055c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:577b055c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:577b741a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:577ba2f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:577bce10-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.172']} DrugCentral uuid:577bfba6-6b31-11ec-b3df-0242ac110002 UniProtKB:P07339 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Enzyme (Cathepsin D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:577c2932-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:577c5736-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.44']} DrugCentral uuid:577c84cc-6b31-11ec-b3df-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:577cb276-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amprenavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:577ce08e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:577d0e10-6b31-11ec-b3df-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:577d3b9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:577d774c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:577d774c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:577d774c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:577d774c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:577dcf44-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:577dfca8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:577e2aac-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:577e5838-6b31-11ec-b3df-0242ac110002 UniProtKB:Q969P6 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase I, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:577e85a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:577eb3c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:577ee186-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:577f1340-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:577f1340-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amsacrine targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:577f515c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagrelide is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:577f7f10-6b31-11ec-b3df-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagrelide targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:577fac88-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anastrozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:577fd9ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androisoxazole targets Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:5780030e-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5780309a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:57805e44-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:57808c66-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5780ba06-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.17']} DrugCentral uuid:5780e7a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenediol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:57811528-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:578146e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:578178a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:5781a92a-6b31-11ec-b3df-0242ac110002 UniProtKB:P37058 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Enzyme (Testosterone 17-beta-dehydrogenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:5781d72e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:578204b0-6b31-11ec-b3df-0242ac110002 UniProtKB:O54939 biolink:molecularly_interacts_with DrugCentral:215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstenedione targets Enzyme (Testosterone 17-beta-dehydrogenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5782321e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05121 biolink:molecularly_interacts_with DrugCentral:217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anecortave targets Secreted (Plasminogen activator inhibitor 1) DrugCentral uuid:57825b9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:57828458-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:5782ad16-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:5782d5ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:578300b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P68371 biolink:molecularly_interacts_with DrugCentral:219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anhydrovinblastine targets Structural (Tubulin beta-4B chain) DrugCentral uuid:57832a66-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anileridine is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:57835342-6b31-11ec-b3df-0242ac110002 UniProtKB:P38435 biolink:molecularly_interacts_with DrugCentral:222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anisindione is inhibitor of Enzyme (Vitamin K-dependent gamma-carboxylase) DrugCentral uuid:57837c0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anisindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5783aa04-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octatropine methylbromide is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5783d2cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octatropine methylbromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:5783fb9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:224 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 antazoline is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5784245c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:224 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 antazoline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:5784527e-6b31-11ec-b3df-0242ac110002 UniProtKB:O75342 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (Arachidonate 12-lipoxygenase, 12R-type) DrugCentral uuid:57847b46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BEG3 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:5784a8c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NXA8 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (NAD-dependent protein deacylase sirtuin-5, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5784d852-6b31-11ec-b3df-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:57850624-6b31-11ec-b3df-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dithranol targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:578533c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.34']} DrugCentral uuid:5785620e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:57858fc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5785bd58-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:5785eb20-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5786197e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5786471e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:578675b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5786a678-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5786d814-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:57870690-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:578734b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:5787622a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.91']} DrugCentral uuid:57879056-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5787bdf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5787ec5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.187']} DrugCentral uuid:578819ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5788479e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:578876a6-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5788a482-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5788d236-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:5788ffc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:57892dee-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:57895b84-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5789891a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:5789b7b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5789e54a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61616 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:578a12e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578a4efe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:578a4efe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:578a4efe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:578a4efe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578add9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:578bc572-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:578bc572-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:578bc572-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:578c120c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:578c120c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:578c6072-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:578c6072-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:578c6072-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:578c6072-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:578c6072-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:578cccc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:578cccc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:578cccc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:578d168e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34949 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Enzyme (Mannose-6-phosphate isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:578d441a-6b31-11ec-b3df-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:578d7200-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00987 biolink:molecularly_interacts_with DrugCentral:228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apomorphine targets Nuclear other (E3 ubiquitin-protein ligase Mdm2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:578d9f82-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:578dcd22-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.938']} DrugCentral uuid:578dfbee-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:578e298e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:578e5f9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:578e5f9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:578e5f9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apraclonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:578ea864-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprepitant targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:578ed168-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprepitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:578efefe-6b31-11ec-b3df-0242ac110002 UniProtKB:P29371 biolink:molecularly_interacts_with DrugCentral:230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprepitant targets GPCR (Neuromedin-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:578f2db6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5DUB1 biolink:molecularly_interacts_with DrugCentral:230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprepitant targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:578f5b2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:578f83e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:578fac96-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.757']} DrugCentral uuid:578fdb30-6b31-11ec-b3df-0242ac110002 UniProtKB:P25786 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Enzyme (Proteasome subunit alpha type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:579008bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P32418 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Transporter (Sodium/calcium exchanger 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:57903634-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.359']} DrugCentral uuid:57906cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine is inhibitor of Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['4.745']} DrugCentral uuid:57906cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine is inhibitor of Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['4.745']} DrugCentral uuid:57906cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprindine is inhibitor of Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['4.745']} DrugCentral uuid:5790b988-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:234 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aranidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:5790b988-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:234 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aranidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:5790ef48-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arbutamine is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:579118c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:5791465a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:579173e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.06']} DrugCentral uuid:5791a2b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5791d03e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00735 biolink:molecularly_interacts_with DrugCentral:239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 argatroban targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.02']} DrugCentral uuid:5791fdd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.851']} DrugCentral uuid:57922b56-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.788']} DrugCentral uuid:5792595a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5792884e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is partial agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.71']} DrugCentral uuid:5792b5e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.131']} DrugCentral uuid:5792e42e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:579311c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:57933f28-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:57936de0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:57939d2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5793caa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.444']} DrugCentral uuid:5793f81e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:57942604-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.51']} DrugCentral uuid:5794539a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:57948126-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:5794af48-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.991']} DrugCentral uuid:5794dcc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.53']} DrugCentral uuid:57950a38-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.681']} DrugCentral uuid:579537ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:5795662c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.169']} DrugCentral uuid:5795949e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.455']} DrugCentral uuid:5795c20c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5795efe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.818']} DrugCentral uuid:57961d74-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.633']} DrugCentral uuid:57964b0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5796794a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5796a6f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.421']} DrugCentral uuid:5796d476-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.492']} DrugCentral uuid:579701da-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:579731c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.202']} DrugCentral uuid:57975f5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.463']} DrugCentral uuid:57978ce0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.906']} DrugCentral uuid:5797bac6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.097']} DrugCentral uuid:5797e834-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:579815c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:57984450-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:579872a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:5798a030-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5798cdb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5798fdaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:57992b40-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:579958cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:579986bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5799b466-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5799e206-6b31-11ec-b3df-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:579a10b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:579a405c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:244 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arsenic trioxide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:579a6e24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:244 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arsenic trioxide is inhibitor of Enzyme (Thioredoxin reductase 1, cytoplasmic) DrugCentral uuid:579a96d8-6b31-11ec-b3df-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.312']} DrugCentral uuid:579ac5e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.998']} DrugCentral uuid:579af416-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:579b21b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.698']} DrugCentral uuid:579b4f56-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.822']} DrugCentral uuid:579b7d6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.741']} DrugCentral uuid:579bab04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.025']} DrugCentral uuid:579bd89a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.046']} DrugCentral uuid:579c06c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.481']} DrugCentral uuid:579c3448-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:579c61c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:579c9000-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.865']} DrugCentral uuid:579cbdbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.359']} DrugCentral uuid:579ceb36-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.253']} DrugCentral uuid:579d18d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.126']} DrugCentral uuid:579d46f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.027']} DrugCentral uuid:579d74a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.819']} DrugCentral uuid:579da242-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.756']} DrugCentral uuid:579dd096-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:579dfe40-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.781']} DrugCentral uuid:579e2bfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:579e5980-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:579e8b9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:579eb948-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:579ee774-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:579f1564-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.297']} DrugCentral uuid:579f42d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.219']} DrugCentral uuid:579f705e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.545']} DrugCentral uuid:579f9e9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.101']} DrugCentral uuid:579fcc0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.784']} DrugCentral uuid:579ff998-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.671']} DrugCentral uuid:57a02742-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:57a057da-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:57a08584-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.577']} DrugCentral uuid:57a0b2fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:57a0dc14-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:57a111de-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:57a111de-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:57a111de-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:57a15a54-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:57a189ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:57a1b774-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.218']} DrugCentral uuid:57a1e4e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.065']} DrugCentral uuid:57a21368-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.701']} DrugCentral uuid:57a241c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.546']} DrugCentral uuid:57a26f48-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.883']} DrugCentral uuid:57a29c98-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.002']} DrugCentral uuid:57a2ca88-6b31-11ec-b3df-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:57a2f92c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:57a326e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:57a35516-6b31-11ec-b3df-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.87']} DrugCentral uuid:57a382a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.673']} DrugCentral uuid:57a3b038-6b31-11ec-b3df-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.868']} DrugCentral uuid:57a3ddce-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.733']} DrugCentral uuid:57a40fd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:57a43dfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:57a46b7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:57a49da4-6b31-11ec-b3df-0242ac110002 UniProtKB:P49355 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:57a49da4-6b31-11ec-b3df-0242ac110002 UniProtKB:P49355 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:57a4d8aa-6b31-11ec-b3df-0242ac110002 UniProtKB:O75530 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Unclassified (Polycomb protein EED) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:57a5062c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:57a53480-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:57a56216-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 astemizole is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['8.58']} DrugCentral uuid:57a58f34-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asulacrine targets Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:57a5b888-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.629']} DrugCentral uuid:57a5e6be-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:57a614ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.921']} DrugCentral uuid:57a64258-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.921']} DrugCentral uuid:57a6705c-6b31-11ec-b3df-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.575']} DrugCentral uuid:57a69e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:57a6cb9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:57a6f9aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P22309 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (UDP-glucuronosyltransferase 1-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.721']} DrugCentral uuid:57a72736-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:57a754b8-6b31-11ec-b3df-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.27']} DrugCentral uuid:57a78352-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:254 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atazanavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.12']} DrugCentral uuid:57a7b48a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:57a7e3d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:57a8115a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:57a83f36-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:57a86d4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.93']} DrugCentral uuid:57a89ae4-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atenolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:57a8c938-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:57a8f6a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:57a92586-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.69']} DrugCentral uuid:57a95308-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.97']} DrugCentral uuid:57a9836e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:57a9b104-6b31-11ec-b3df-0242ac110002 UniProtKB:P48051 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.282']} DrugCentral uuid:57a9de90-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:57aa0c6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:57aa39f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:57aa677a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:57aa99c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.478']} DrugCentral uuid:57aa99c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.478']} DrugCentral uuid:57aad912-6b31-11ec-b3df-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.845']} DrugCentral uuid:57aad912-6b31-11ec-b3df-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.845']} DrugCentral uuid:57ab13fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13118 biolink:molecularly_interacts_with DrugCentral:256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atomoxetine targets Nuclear other (Krueppel-like factor 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:57ab4320-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:57ab6f26-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:57ab9e1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:57abccbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:57abfab8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:57ac2830-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:57ac55b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:57ac8398-6b31-11ec-b3df-0242ac110002 UniProtKB:Q1W675 biolink:molecularly_interacts_with DrugCentral:257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atorvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:57acb106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:57acde56-6b31-11ec-b3df-0242ac110002 UniProtKB:P43264 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone targets Enzyme (Ubiquinol-cytochrome-c reductase complex core protein I, mitochondrial) DrugCentral uuid:57ad07aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02768 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone is inhibitor of Enzyme (Cytochrome b) DrugCentral uuid:57ad3464-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63707 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:57ad6236-6b31-11ec-b3df-0242ac110002 UniProtKB:Q54A96 biolink:molecularly_interacts_with DrugCentral:258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atovaquone targets Enzyme (Dihydroorotate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:57ad8fb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:57adb8e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:57ade698-6b31-11ec-b3df-0242ac110002 UniProtKB:P70605 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:57ae1cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:57ae1cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:57ae1cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:57ae6604-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:57ae939a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atracurium is antagonist of Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:57aec108-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:57aef0a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:57af1f04-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.276']} DrugCentral uuid:57af4c90-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.907']} DrugCentral uuid:57af7a30-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:57afa82a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.97']} DrugCentral uuid:57afd5b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:57b00450-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:57b033b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.29']} DrugCentral uuid:57b06152-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:57b08ede-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:57b0bdbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:57b0ee6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.59']} DrugCentral uuid:57b11bec-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:57b14964-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:57b17768-6b31-11ec-b3df-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:57b1a4e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WMX0 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:57b1d280-6b31-11ec-b3df-0242ac110002 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:57b200d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:57b22e60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.99']} DrugCentral uuid:57b25c0a-6b31-11ec-b3df-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:57b29c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:57b29c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:57b29c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:57b29c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:57b29c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:57b30510-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atropine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.99']} DrugCentral uuid:57b33b7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:57b33b7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:57b33b7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:57b38cec-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:57b38cec-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:57b38cec-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:57b3d706-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapropazone targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:57b3ff9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azapropazone targets Enzyme (Xanthine dehydrogenase/oxidase) DrugCentral uuid:57b42846-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azasetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.268']} DrugCentral uuid:57b455aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azatadine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:57b47fa8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azatadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:57b4ad02-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:57b4d5ac-6b31-11ec-b3df-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:57b4fe9c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:57b52746-6b31-11ec-b3df-0242ac110002 UniProtKB:P63000 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Enzyme (Ras-related C3 botulinum toxin substrate 1) DrugCentral uuid:57b54fc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P51580 biolink:molecularly_interacts_with DrugCentral:269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azathioprine targets Enzyme (Thiopurine S-methyltransferase) DrugCentral uuid:57b57872-6b31-11ec-b3df-0242ac110002 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelaic acid targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) DrugCentral uuid:57b5a19e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:57b5cf02-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:57b5f7e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:57b62560-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:57b655d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:57b6837a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.168']} DrugCentral uuid:57b6b11a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:57b6e04a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:57b70dcc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:57b73b44-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:57b76dd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:57b76dd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azelnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:57b7a250-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azimilide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:57b7cfc8-6b31-11ec-b3df-0242ac110002 UniProtKB:O08703 biolink:molecularly_interacts_with DrugCentral:274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azimilide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:57b7fd36-6b31-11ec-b3df-0242ac110002 UniProtKB:O70344 biolink:molecularly_interacts_with DrugCentral:274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azimilide targets Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:57b82d42-6b31-11ec-b3df-0242ac110002 UniProtKB:P97414 biolink:molecularly_interacts_with DrugCentral:274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azimilide is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:57b85bbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azithromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.39']} DrugCentral uuid:57b88922-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azithromycin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.7']} DrugCentral uuid:57b8b6e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azithromycin targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:57b8e444-6b31-11ec-b3df-0242ac110002 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azithromycin is agonist of GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:57b926ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:57b926ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:57b926ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:57b926ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:57b926ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:57b926ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X6W0 biolink:molecularly_interacts_with DrugCentral:277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azlocillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:57b98a7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.736']} DrugCentral uuid:57b9b7fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07806 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:57b9e6fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.317']} DrugCentral uuid:57ba1508-6b31-11ec-b3df-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.317']} DrugCentral uuid:57ba428a-6b31-11ec-b3df-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:57ba7002-6b31-11ec-b3df-0242ac110002 UniProtKB:A4ZYU9 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:57ba9ea6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q83TT7 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Unclassified (AmpC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:57bacc50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3S5C3 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Transporter (Efflux transporter; SugE) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:57baf9f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q48435 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:57bb27c2-6b31-11ec-b3df-0242ac110002 UniProtKB:B2ZTR6 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:57bb5530-6b31-11ec-b3df-0242ac110002 UniProtKB:D6NSM8 biolink:molecularly_interacts_with DrugCentral:279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aztreonam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:57bb9bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57bb9bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57bb9bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57bb9bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57bb9bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57bb9bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57bb9bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacampicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:57bc11b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacitracin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.269']} DrugCentral uuid:57bc3f22-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacitracin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.716']} DrugCentral uuid:57bc6cfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacitracin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.868']} DrugCentral uuid:57bc9a80-6b31-11ec-b3df-0242ac110002 UniProtKB:P60932 biolink:molecularly_interacts_with DrugCentral:281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bacitracin targets Unclassified (Undecaprenyl-diphosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:57bccc3a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z0U4 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets GPCR (GABA B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bccc3a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z0U4 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets GPCR (GABA B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bd0d58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen is agonist of GPCR (GABA-B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:57bd0d58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen is agonist of GPCR (GABA-B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:57bd4836-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57bdb94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baclofen targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57beb43c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 balsalazide is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:57bedd4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 balsalazide is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:57bf05fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 balsalazide is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:57bf2e8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 balsalazide is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) DrugCentral uuid:57bf5716-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:57bf81aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:57bfaee6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.25']} DrugCentral uuid:57bfdc54-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol is inhibitor of Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:57c00a30-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bambuterol targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:57c0378a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bamipine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:57c06462-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 barnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:57c06462-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 barnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:57c0995a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.427']} DrugCentral uuid:57c0c6be-6b31-11ec-b3df-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:57c0f440-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:57c121a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:57c151ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:57c17f32-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:57c1acc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:57c1db3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:57c2089e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86Y34 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate is agonist of GPCR (Probable G-protein coupled receptor 97) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:57c235ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P04401 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Unclassified (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:57c26352-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclometasone dipropionate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:57c292aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belotecan is inhibitor of Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.561']} DrugCentral uuid:57c2c022-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benazepril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.51']} DrugCentral uuid:57c2eda4-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benazepril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:57c31d56-6b31-11ec-b3df-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benazepril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:57c34be6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:57c3792c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:57c3a6f4-6b31-11ec-b3df-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:57c3d44e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:57c401a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:57c42ee4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendamustine targets Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:57c45c98-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide targets Enzyme (Carbonic anhydrase 2) DrugCentral uuid:57c48542-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['8.3']} DrugCentral uuid:57c4b260-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:57c4dc86-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide targets Enzyme (Carbonic anhydrase 4) DrugCentral uuid:57c50576-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bendroflumethiazide targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:57c52e2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benoxaprofen is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:57c556b6-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benoxaprofen targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:57c5847e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.57']} DrugCentral uuid:57c5b200-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:57c5df46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:57c60ca0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:57c63a86-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.18']} DrugCentral uuid:57c667f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:57c69576-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:57c6c5be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:57c6f336-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.131']} DrugCentral uuid:57c720d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.105']} DrugCentral uuid:57c74ec6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.108']} DrugCentral uuid:57c77c34-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.562']} DrugCentral uuid:57c7a9b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:57c7d828-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:57c80618-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:57c8337c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.486']} DrugCentral uuid:57c860c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:57c89b5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:57c89b5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:57c89b5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:57c8e394-6b31-11ec-b3df-0242ac110002 UniProtKB:P20711 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Enzyme (Aromatic-L-amino-acid decarboxylase) DrugCentral uuid:57c90cfc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:57c93aba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:57c96c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:57c96c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:57c9a8a6-6b31-11ec-b3df-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:57c9d682-6b31-11ec-b3df-0242ac110002 UniProtKB:P03313 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Unclassified (Genome polyprotein [Cleaved into: P1; Capsid protein VP0) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:57ca03f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P52789 biolink:molecularly_interacts_with DrugCentral:314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benserazide targets Kinase (Hexokinase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:57ca3154-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzarone targets Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:57ca5fd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99504 biolink:molecularly_interacts_with DrugCentral:317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzarone targets Enzyme (Eyes absent homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:57ca8d48-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:57cabaca-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:57cae84c-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:57cb1632-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:57cb438c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:57cb70e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:57cb9eae-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.976']} DrugCentral uuid:57cbcbf4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.908']} DrugCentral uuid:57cbfa66-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.711']} DrugCentral uuid:57cc27ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:57cc563c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:57cc83b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.32']} DrugCentral uuid:57ccb140-6b31-11ec-b3df-0242ac110002 UniProtKB:O00167 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Eyes absent homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:57ccdf1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99504 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone targets Enzyme (Eyes absent homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:57cd0ca8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzbromarone is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:57cd3a02-6b31-11ec-b3df-0242ac110002 UniProtKB:O15392 biolink:molecularly_interacts_with DrugCentral:321 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benziodarone targets Unclassified (Baculoviral IAP repeat-containing protein 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:57cd6842-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99504 biolink:molecularly_interacts_with DrugCentral:321 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benziodarone targets Enzyme (Eyes absent homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:57cd95ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:57cdbe6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:57cde718-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:57ce110c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:57ce39ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:57ce6274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:57ce8baa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UI33 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 11 subunit alpha) DrugCentral uuid:57ceb4e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:57cedd9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01118 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 7 subunit alpha) DrugCentral uuid:57cf063e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['3.495']} DrugCentral uuid:57cf3398-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzonatate targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:57cf5cce-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzphetamine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:57cf8578-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzphetamine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:57cfae04-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzphetamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:57cfd7b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzphetamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:57d00282-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:57d03022-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:57d05d86-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.445']} DrugCentral uuid:57d08c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.241']} DrugCentral uuid:57d0ba9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.865']} DrugCentral uuid:57d0e80a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:57d11776-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzquinamide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.264']} DrugCentral uuid:57d144f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide targets Enzyme (Carbonic anhydrase 2) DrugCentral uuid:57d16dac-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['8.17']} DrugCentral uuid:57d19ade-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:57d1c662-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide targets Enzyme (Carbonic anhydrase 4) DrugCentral uuid:57d1f268-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzthiazide targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:57d21c16-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:57d249fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:57d277a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:57d2a50a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:57d2d278-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.157']} DrugCentral uuid:57d300a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:57d32e26-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:57d35ba8-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.888']} DrugCentral uuid:57d38aba-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:57d3b85a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.654']} DrugCentral uuid:57d3e5c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:57d41354-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.926']} DrugCentral uuid:57d44162-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.636']} DrugCentral uuid:57d46ec6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.854']} DrugCentral uuid:57d49c48-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:57d4ca92-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:57d4f80a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:57d52578-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:57d5550c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.253']} DrugCentral uuid:57d58680-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:57d5b45c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:57d5e1d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:57d60fec-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:57d63d8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:57d66b04-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:57d698f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:57d6c662-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:57d6f3da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q695T7 biolink:molecularly_interacts_with DrugCentral:333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzatropine is inhibitor of Transporter (Sodium-dependent neutral amino acid transporter B(0)AT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:57d72120-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzyl benzoate targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:57d750e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P15304 biolink:molecularly_interacts_with DrugCentral:335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzyl benzoate targets Enzyme (Hormone-sensitive lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:57d77e54-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepotastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:57d7a6cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:57d7cfa8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:57d7fd02-6b31-11ec-b3df-0242ac110002 UniProtKB:O00555 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:57d82a7a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.149']} DrugCentral uuid:57d857e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:57d88754-6b31-11ec-b3df-0242ac110002 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:57d8b49a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:57d8e1ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:57d91930-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:57d91930-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:57d91930-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:57d96156-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z258 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is gating inhibitor of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:57d98fc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:57d9b8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bepridil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:57d9e176-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:57da0eee-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:57da3d24-6b31-11ec-b3df-0242ac110002 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:57da6a9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43253 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:57da981e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beraprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:57dac582-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2Q167 biolink:molecularly_interacts_with DrugCentral:345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betacarotene targets Unclassified (Core protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:57daf3c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betahistine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:57db213a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betahistine is inverse agonist of GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.523']} DrugCentral uuid:57db4e9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:57db7c34-6b31-11ec-b3df-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone targets Cytosolic other (Annexin A1) DrugCentral uuid:57dba4fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:57dbcd9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone benzoate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:57dbf664-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone dipropionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:57dc2026-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone dipropionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:57dc4d94-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone valerate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:57dc7620-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamipron targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:57dca38e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamipron targets Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:57dcd480-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:57dd0266-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:57dd2fe8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.98']} DrugCentral uuid:57dd5dce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:57dd8b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.53']} DrugCentral uuid:57ddb896-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betaxolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.76']} DrugCentral uuid:57dde6fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:357 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betazole is agonist of GPCR (Histamine H2 receptor) DrugCentral uuid:57de0f94-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:57de3e42-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:57de6bb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:57de9a5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:57dec7d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.9']} DrugCentral uuid:57def53a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VH27 biolink:molecularly_interacts_with DrugCentral:358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bethanechol targets GPCR (Muscarinic receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:57df22da-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betanidine is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:57df4b84-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bevantolol is antagonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:57df741a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:57dfa1b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene is antagonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:57dfd13a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:57dffebc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28702 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:57e02c34-6b31-11ec-b3df-0242ac110002 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:57e05b14-6b31-11ec-b3df-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:57e089c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:57e0b730-6b31-11ec-b3df-0242ac110002 UniProtKB:P28704 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Transcription factor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:57e0e49e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28705 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Transcription factor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:57e1125c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28700 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Transcription factor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:57e13fac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05343 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:57e16cf2-6b31-11ec-b3df-0242ac110002 UniProtKB:O43174 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Enzyme (Cytochrome P450 26A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:57e19ace-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NR63 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Enzyme (Cytochrome P450 26B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:57e1c83c-6b31-11ec-b3df-0242ac110002 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:57e1f686-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13133 biolink:molecularly_interacts_with DrugCentral:361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bexarotene targets Nuclear other (Oxysterols receptor LXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:57e2244e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Enzyme (Lipoprotein lipase) DrugCentral uuid:57e24d66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:57e27aac-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.178']} DrugCentral uuid:57e2a928-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:57e2d736-6b31-11ec-b3df-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.48']} DrugCentral uuid:57e304ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:57e33244-6b31-11ec-b3df-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezafibrate is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) DrugCentral uuid:57e35ad0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X6V3 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (Penicillin-binding protein 2) DrugCentral uuid:57e383d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (Penicillin-binding protein 4) DrugCentral uuid:57e3ac74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X6V7 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (D-ala-D-ala-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase family protein; Penicillin-binding protein 5) DrugCentral uuid:57e3d500-6b31-11ec-b3df-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:57e3fe54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7CHG0 biolink:molecularly_interacts_with DrugCentral:365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biapenem targets Enzyme (D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6) DrugCentral uuid:57e426fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:57e45480-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:57e481da-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:57e4b01a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:57e4dd74-6b31-11ec-b3df-0242ac110002 UniProtKB:P06186 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:57e50ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63449 biolink:molecularly_interacts_with DrugCentral:367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bicalutamide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:57e538e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y468 biolink:molecularly_interacts_with DrugCentral:369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifemelane targets Unclassified (Lethal(3)malignant brain tumor-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:57e566b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifonazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:57e593f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifonazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:57e5c16c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifonazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:57e5ef84-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bifonazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:57e61d74-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bimatoprost targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:57e64ad8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bimatoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:57e67922-6b31-11ec-b3df-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biotin targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:57e6a668-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.32']} DrugCentral uuid:57e6d476-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:57e701e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:57e731e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.62']} DrugCentral uuid:57e75f40-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.201']} DrugCentral uuid:57e78cae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biperiden targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:57e7b620-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisacodyl targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.756']} DrugCentral uuid:57e7e384-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisacodyl targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.011']} DrugCentral uuid:57e81106-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisacodyl targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:57e83ed8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15559 biolink:molecularly_interacts_with DrugCentral:376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisantrene targets Enzyme (NAD(P)H dehydrogenase [quinone] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:57e86c3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:57e899aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:57e8c70e-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:57e8f4ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:57e92280-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:57e95016-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bisulepine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:57e979e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bitolterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:57e9a0d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bivalirudin is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:57e9c9b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blonanserin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:57e9f28c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blonanserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:57ea1c30-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blonanserin is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.854']} DrugCentral uuid:57ea4534-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blonanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.092']} DrugCentral uuid:57ea6e24-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.815']} DrugCentral uuid:57ea971e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.345']} DrugCentral uuid:57eac07c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.014']} DrugCentral uuid:57eae976-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.463']} DrugCentral uuid:57eb1252-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.262']} DrugCentral uuid:57eb3b1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:57eb6694-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:57eb90d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bopindolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.65']} DrugCentral uuid:57ebb9d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:57ebe2b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:57ec0c52-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:57ec354c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:57ec5e32-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:57ec879a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:57ecb076-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:57ecd970-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:57ed0242-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:57ed2c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.745']} DrugCentral uuid:57ed55da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99460 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Cytosolic other (26S proteasome non-ATPase regulatory subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:57ed7eca-6b31-11ec-b3df-0242ac110002 UniProtKB:P25786 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit alpha type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.208']} DrugCentral uuid:57eda8b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:57edd244-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:57edfb5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:57ee2456-6b31-11ec-b3df-0242ac110002 UniProtKB:P08311 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Cathepsin G) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:57ee4e90-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:57ee77d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23946 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Chymase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:57eea0ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P17538 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Chymotrypsinogen B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:57eec9ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P28062 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:57eef2a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:57ef1c58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:57ef4520-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:57ef6e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:57ef97dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P49721 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:57efc1e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib is inhibitor of Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:57efeaf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:57f013e2-6b31-11ec-b3df-0242ac110002 UniProtKB:A5PKW4 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Unclassified (PH and SEC7 domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:57f044f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04206 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Transcription factor (Nuclear factor NF-kappa-B complex) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:57f044f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04206 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Transcription factor (Nuclear factor NF-kappa-B complex) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:57f044f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04206 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Transcription factor (Nuclear factor NF-kappa-B complex) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:57f085c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00766 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Alpha-chymotrypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:57f0ae92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IJT1 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:57f0d85e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28063 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta type-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.78']} DrugCentral uuid:57f10162-6b31-11ec-b3df-0242ac110002 UniProtKB:P28065 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta type-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:57f12a34-6b31-11ec-b3df-0242ac110002 UniProtKB:P40306 biolink:molecularly_interacts_with DrugCentral:391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bortezomib targets Enzyme (Proteasome subunit beta type-10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:57f1531a-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:57f17868-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:57f1a162-6b31-11ec-b3df-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:57f1ca70-6b31-11ec-b3df-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:57f1f374-6b31-11ec-b3df-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:57f21cd2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q29010 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:57f245a4-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:57f26e58-6b31-11ec-b3df-0242ac110002 UniProtKB:P21451 biolink:molecularly_interacts_with DrugCentral:392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosentan targets GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:57f2970c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bretylium targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:57f2bc82-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bretylium targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:57f2e126-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bretylium is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:57f305b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.387']} DrugCentral uuid:57f32e74-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.836']} DrugCentral uuid:57f35886-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:57f381a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:57f3ab7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.469']} DrugCentral uuid:57f3d450-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.073']} DrugCentral uuid:57f3fdb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:57f426b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:57f44f8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:57f47982-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:57f4aa06-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57f4aa06-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57f4aa06-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57f4f3d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:57f4f3d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:57f4f3d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:57f5358e-6b31-11ec-b3df-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brimonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:57f55e7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:57f5878c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:57f5b0d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:57f5d9d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:57f602ca-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:57f62bc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:57f65554-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:57f67e62-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:57f6a75c-6b31-11ec-b3df-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:57f6d042-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:57f6f9a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:57f722b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:57f74bb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:57f775b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:57f79f40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:57f7c830-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:57f7f116-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:57f81a24-6b31-11ec-b3df-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:57f8440e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:57f86d12-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:57f895f8-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:57f8bfd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:57f8e8c8-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:57f9123a-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:57f93b34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:57f964e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:57f98db4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:57f9b69a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:57f9df8a-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brinzolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:57fa0b04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:57fa34bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivudine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:57fa5dac-6b31-11ec-b3df-0242ac110002 UniProtKB:P06479 biolink:molecularly_interacts_with DrugCentral:397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:57fa86a6-6b31-11ec-b3df-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:57faafd2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:57fad8b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:57fb01a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:57fb2b06-6b31-11ec-b3df-0242ac110002 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:57fb5540-6b31-11ec-b3df-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:57fb7f20-6b31-11ec-b3df-0242ac110002 UniProtKB:P00378 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.54']} DrugCentral uuid:57fba7f2-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:57fbd16e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8Z9J9 biolink:molecularly_interacts_with DrugCentral:398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodimoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:57fc0210-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:57fc0210-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:57fc0210-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:57fc3b86-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromfenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:57fc64da-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromfenac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:57fc9194-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromfenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:57fc9194-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromfenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:57fcc650-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromhexine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:57fcefb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromhexine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.954']} DrugCentral uuid:57fd195c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromhexine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.708']} DrugCentral uuid:57fd424c-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromhexine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:57fd6b28-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.858']} DrugCentral uuid:57fd940e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:57fdc0aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:57fded00-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:57fe164a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:57fe3fd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:57fe68b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:57fe9188-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:57feba64-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:57fee3ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:57ff0cda-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:57ff35ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:57ff5fa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:57ff8b56-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:57ffb6d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:57ffe042-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5800091e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:58003272-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:58005b6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5800845c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:5800adb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.86']} DrugCentral uuid:5800d6aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.818']} DrugCentral uuid:5800ffae-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.708']} DrugCentral uuid:580128c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:58015350-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.16']} DrugCentral uuid:58017e84-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5801a792-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:5801d186-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5801fb0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7TSF2 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets Transporter (Vesicular glutamate transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:580223ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:58025480-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:58025480-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:58025480-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5802a4ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5802a4ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5802a4ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5802a4ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5802a4ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5803029a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5803029a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromocriptine targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:58033a1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:5803630c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:58038bf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromopride targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:5803b4ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5803de68-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:58040758-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:58043020-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5804596a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:58048250-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:5804ab4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.119']} DrugCentral uuid:5804d430-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.745']} DrugCentral uuid:5804feec-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.146']} DrugCentral uuid:58052b24-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5805552c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.319']} DrugCentral uuid:58057e26-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bromperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5805a7ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5805d0b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.218']} DrugCentral uuid:58060166-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:58060166-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:58060166-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brompheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:580642a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:409 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brotizolam targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:58066ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 broxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:58069586-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buclizine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5806b9f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5806df82-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:58070854-6b31-11ec-b3df-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:58073126-6b31-11ec-b3df-0242ac110002 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Cytokine (Interferon gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.5']} DrugCentral uuid:58075a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:58078446-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5807ad22-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.701']} DrugCentral uuid:5807d720-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.963']} DrugCentral uuid:58080074-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:58082982-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:5808524a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04401 biolink:molecularly_interacts_with DrugCentral:419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budesonide targets Unclassified (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:58087b1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5808be4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:5808be4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:5808be4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:5808be4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:5808be4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:5808be4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:5808be4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 budipine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:58092e68-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:58095384-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:58097ca6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5809a5a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5809ca1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:5809ef42-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-1D adrenergic receptor) DrugCentral uuid:580a13be-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:580a3952-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:580a5dec-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buflomedil targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:580a879a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufuralol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:580ab080-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufuralol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:580ad970-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufuralol targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:580afe00-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufuralol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ks', 'has_quantitative_value': ['4.59']} DrugCentral uuid:580b2772-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bumetanide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:580b506c-6b31-11ec-b3df-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bumetanide targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:580b7952-6b31-11ec-b3df-0242ac110002 UniProtKB:P55011 biolink:molecularly_interacts_with DrugCentral:427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bumetanide is inhibitor of Transporter (Solute carrier family 12 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:580ba224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bumetanide is agonist of GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:580bcbbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bunazosin is antagonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:580bf03a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bunazosin targets GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:580c14e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bunazosin is antagonist of GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:580c39d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bunazosin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) DrugCentral uuid:580c62d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.399']} DrugCentral uuid:580c8bd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.263']} DrugCentral uuid:580cb4de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:580cde14-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.585']} DrugCentral uuid:580d0722-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:580d301c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.593']} DrugCentral uuid:580d58ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:580d827e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:580dab64-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobunolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:580dd5a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:580dfe7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:580e28f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.293']} DrugCentral uuid:580e52c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:580e7ba2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.514']} DrugCentral uuid:580ea474-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:580ecdaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.233']} DrugCentral uuid:580ef67c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:580f1f58-6b31-11ec-b3df-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:580f4848-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:580f71ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z0V1 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine is blocker of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:580f9ad2-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:580fc3a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupranolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:580fedac-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupranolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:58101764-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupranolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:58104068-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.29']} DrugCentral uuid:58106958-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:581092b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.01']} DrugCentral uuid:5810bbba-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:5810e4c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:58110dc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.89']} DrugCentral uuid:5811393c-6b31-11ec-b3df-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:581163d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:58118cca-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buprenorphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5811b59c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5811e120-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:58120a1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.796']} DrugCentral uuid:58123396-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:58125dee-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Enzyme (Cytochrome P450 2D6) DrugCentral uuid:5812827e-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5812ab64-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5812d440-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.846']} DrugCentral uuid:5812fdd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:58132a80-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:58132a80-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:58136342-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:58136342-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bupropion targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5813992a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buserelin targets GPCR (Lutropin-choriogonadotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.569']} DrugCentral uuid:5813c2e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buserelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.52']} DrugCentral uuid:5813ebb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01776 biolink:molecularly_interacts_with DrugCentral:436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buserelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:58141454-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:58143d80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:58146670-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:58149104-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5814b9d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:5814e348-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:58150c2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5815351e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:58155e04-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.435']} DrugCentral uuid:58158910-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5815b1e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5815dadc-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.277']} DrugCentral uuid:581603d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:58162f82-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.471']} DrugCentral uuid:58165868-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:58168158-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5816aa98-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:5816d37e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:5816fc64-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:58172572-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:58174f98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:58177860-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5817a15a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5817ca4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5817f3d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:58181cac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:581845ba-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:58186eaa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:581897fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:5818cc1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5818cc1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5818cc1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5818cc1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:58192250-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:58192250-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:58192250-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5819789a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5819789a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5819789a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5819789a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5819789a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5819dad8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:5819dad8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:5819dad8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:581a2380-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:581a2380-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:581a2380-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buspirone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:581a6638-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:438 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 busulfan targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.283']} DrugCentral uuid:581a96da-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secbutabarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:581a96da-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secbutabarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:581a96da-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secbutabarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:581ad7ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butalbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:581ad7ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butalbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:581ad7ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butalbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:581b160a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.864']} DrugCentral uuid:581b4238-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.779']} DrugCentral uuid:581b6c22-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.125']} DrugCentral uuid:581b9580-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.411']} DrugCentral uuid:581bbe52-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:581be710-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.161']} DrugCentral uuid:581c0ff6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4JEY0 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine is inhibitor of Enzyme (Squalene epoxidase) DrugCentral uuid:581c34ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.805']} DrugCentral uuid:581c5df8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:581c86b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92206 biolink:molecularly_interacts_with DrugCentral:444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butenafine targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.347']} DrugCentral uuid:581cb0aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:450 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butoconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:581cd85a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butorphanol is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:581d021c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butorphanol is partial agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:581d2b16-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butorphanol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:581d5406-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:455 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butriptyline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.866']} DrugCentral uuid:581d7d50-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:455 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butriptyline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:581da64a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:455 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.405']} DrugCentral uuid:581dcf30-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:581df3de-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:581e18d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:581e3d4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine butylbromide targets GPCR (Muscarinic acetylcholine receptor M4) DrugCentral uuid:581e61e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:581e8aec-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:581eb51c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:581ede0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:581f0710-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:581f3078-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:581f5972-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:581f826c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:581fab66-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:581fd4b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:581ffdaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:58202690-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:58204f80-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:58207c26-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5820a674-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5820d04a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:5820f926-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabergoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:58212252-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:461 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cadralazine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:582146e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:461 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cadralazine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:58216fbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:582198a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5821c1ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:5821eaf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:58221478-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:58223e9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:58226784-6b31-11ec-b3df-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:5822906a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00489 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Enzyme (Glycogen phosphorylase, muscle form) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:5822b93c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5822e268-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:58230b58-6b31-11ec-b3df-0242ac110002 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5823343e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:58236120-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:58236120-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5823a1c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5823a1c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5823a1c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5823a1c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5823ef96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2T3 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets Enzyme (Guanine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:58241a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5824445a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60614 biolink:molecularly_interacts_with DrugCentral:463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caffeine is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:58246d68-6b31-11ec-b3df-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcifediol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:582492de-6b31-11ec-b3df-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:465 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcipotriene is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.51']} DrugCentral uuid:5824bc3c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) DrugCentral uuid:5824e0ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5825099e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6VVX0 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Enzyme (Vitamin D 25-hydroxylase) DrugCentral uuid:58252e24-6b31-11ec-b3df-0242ac110002 UniProtKB:P02774 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Secreted (Vitamin D-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:5825578c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13053 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:58258086-6b31-11ec-b3df-0242ac110002 UniProtKB:O42392 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.6']} DrugCentral uuid:5825a96c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28037 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:5825d248-6b31-11ec-b3df-0242ac110002 UniProtKB:A3RGC1 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.15']} DrugCentral uuid:5825fd68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9PTN2 biolink:molecularly_interacts_with DrugCentral:466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitriol targets Nuclear hormone receptor (Vitamin D3 receptor A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5826264e-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camphor targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:58264f34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camphor is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5826781a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5826a182-6b31-11ec-b3df-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat is inhibitor of Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5826cb9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06870 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Kallikrein-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:5826f466-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01177 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:58271da6-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:58274682-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:58276f68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:58279858-6b31-11ec-b3df-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:5827c2c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04756 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat targets Enzyme (Hepatocyte growth factor activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5827ee98-6b31-11ec-b3df-0242ac110002 UniProtKB:O15393 biolink:molecularly_interacts_with DrugCentral:471 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camostat is inhibitor of Enzyme (Transmembrane protease serine 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:58281788-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:472 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 camylofin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5828403c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:58286968-6b31-11ec-b3df-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5828924e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:5828bc10-6b31-11ec-b3df-0242ac110002 UniProtKB:P34976 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.19']} DrugCentral uuid:5828e514-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBT6 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (DNULL polymerase kappa) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:58290e68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNA4 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (DNULL polymerase iota) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:58293762-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y253 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (DNULL polymerase eta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:58296034-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:58298924-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5829b674-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:5829e2ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:582a0c1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:582a3568-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:582a5e6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.16']} DrugCentral uuid:582a875c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:582ab0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 candesartan cilexetil targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:582ad9fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canrenone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:582b02d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capecitabine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:582b2784-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:582b5100-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:582b7c3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:582ba52e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:582bce00-6b31-11ec-b3df-0242ac110002 UniProtKB:P00797 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:582bf6e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:582c2030-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:582c4920-6b31-11ec-b3df-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:582c722e-6b31-11ec-b3df-0242ac110002 UniProtKB:P44514 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Succinyl-diaminopimelate desuccinylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:582c9ba0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q79MP6 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:582cc59e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q93T40 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Beta-lactamase II) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:582ceeb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9K2N0 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Unclassified (Beta-lactamase class B VIM-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:582d1832-6b31-11ec-b3df-0242ac110002 UniProtKB:C7C422 biolink:molecularly_interacts_with DrugCentral:484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 captopril targets Enzyme (Beta-lactamase NDM-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.85']} DrugCentral uuid:582d42bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.81']} DrugCentral uuid:582d6c24-6b31-11ec-b3df-0242ac110002 UniProtKB:P42785 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets Enzyme (Lysosomal Pro-X carboxypeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:582d950a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:582dbf3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:582de884-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caramiphen targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:582e116a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.94']} DrugCentral uuid:582e3a64-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:582e6354-6b31-11ec-b3df-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:582e8cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:582eb5ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:582edea6-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carazolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:582f0782-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:582f337e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:582f5c46-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:582f850e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.577']} DrugCentral uuid:582fae4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.097']} DrugCentral uuid:582fd70c-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.18']} DrugCentral uuid:58300006-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:583028e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:58305254-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:58307b58-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5830a448-6b31-11ec-b3df-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5830ce28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5830f84e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5831213e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.74']} DrugCentral uuid:58314a06-6b31-11ec-b3df-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:583176c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:583176c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5831aff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5831aff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5831e8bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5831e8bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:583221f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:583221f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:58325acc-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:58325acc-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:58329398-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:58329398-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5832da92-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5832da92-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5832da92-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5832da92-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5832da92-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:488 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbachol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:58333334-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:58335832-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.495']} DrugCentral uuid:58338244-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.125']} DrugCentral uuid:5833ab48-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5833d53c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5833fe72-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:58342aa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:58342aa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:58342aa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:583467cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:583467cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:58349e54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H461 biolink:molecularly_interacts_with DrugCentral:489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamazepine is allosteric modulator of GPCR (Frizzled-8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5834c744-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5834f016-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:583518fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:583554ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:583554ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:583554ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:583554ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:583554ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:583554ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:583554ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5835b78a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenoxolone is inhibitor of Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:5835e0d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:583609b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P51661 biolink:molecularly_interacts_with DrugCentral:493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbenoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5836328c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.71']} DrugCentral uuid:58365b7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:583687aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:5836b09a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42785 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Enzyme (Lysosomal Pro-X carboxypeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:5836d976-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:583702b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:58372cd2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxyverine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:583755b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbetocin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:58377e94-6b31-11ec-b3df-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbetocin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.232']} DrugCentral uuid:5837a810-6b31-11ec-b3df-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbetocin is agonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.149']} DrugCentral uuid:5837d114-6b31-11ec-b3df-0242ac110002 UniProtKB:P20711 biolink:molecularly_interacts_with DrugCentral:496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbidopa is inhibitor of Enzyme (Aromatic-L-amino-acid decarboxylase) DrugCentral uuid:5837f5a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbidopa targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.168']} DrugCentral uuid:58381e8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbidopa targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.428']} DrugCentral uuid:583848d8-6b31-11ec-b3df-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbidopa targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:58387240-6b31-11ec-b3df-0242ac110002 UniProtKB:P22079 biolink:molecularly_interacts_with DrugCentral:497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbimazole targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:58389b1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07202 biolink:molecularly_interacts_with DrugCentral:497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbimazole is inhibitor of Enzyme (Thyroid peroxidase) DrugCentral uuid:5838bfc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbinoxamine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5838e586-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carboprost is agonist of GPCR (Prostaglandin F2-alpha receptor) DrugCentral uuid:58390e08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.602']} DrugCentral uuid:58390e08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.602']} DrugCentral uuid:58395afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58395afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58395afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58395afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58395afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58395afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58395afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carindacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5839be0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:510 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carubicin targets Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:5839e29c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:583a0cea-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.213']} DrugCentral uuid:583a365c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6P7S1 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Enzyme (Acid ceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:583a5f38-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13510 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Enzyme (Acid ceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:583a881e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6N5 biolink:molecularly_interacts_with DrugCentral:511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmofur targets Unclassified (Sulfide:quinone oxidoreductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:583ab1ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carmustine is inhibitor of Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:583adb70-6b31-11ec-b3df-0242ac110002 UniProtKB:P50416 biolink:molecularly_interacts_with DrugCentral:513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocarnitine targets Enzyme (Carnitine O-palmitoyltransferase 1, liver isoform) DrugCentral uuid:583affec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63704 biolink:molecularly_interacts_with DrugCentral:513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocarnitine targets Enzyme (Carnitine O-palmitoyltransferase 1, muscle isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:583b28e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18886 biolink:molecularly_interacts_with DrugCentral:513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocarnitine targets Enzyme (Carnitine palmitoyltransferase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:583b5276-6b31-11ec-b3df-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:515 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carperitide targets Enzyme (Atrial natriuretic peptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10']} DrugCentral uuid:583b7b5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18910 biolink:molecularly_interacts_with DrugCentral:515 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carperitide targets Enzyme (Atrial natriuretic peptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:583ba424-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:516 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfenazine is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:583bc8dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:516 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfenazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:583beeac-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carpipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.06']} DrugCentral uuid:583c1792-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carpipramine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:583c40aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:583c6990-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:583c930c-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:583cbbfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:583ce4d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:583d0daa-6b31-11ec-b3df-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:518 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carprofen targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:583d36fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carteolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:583d5fee-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carteolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:583d88d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carumonam targets Enzyme (Peptidoglycan synthase FtsI) DrugCentral uuid:583dad8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92736 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is inhibitor of Ion channel (Ryanodine receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:583dd78a-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.742']} DrugCentral uuid:583e0098-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:583e2992-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:583e5336-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.126']} DrugCentral uuid:583e7c12-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:583ea598-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:583ecea6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:583ef8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.928']} DrugCentral uuid:583f21b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.273']} DrugCentral uuid:583f4be2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.476']} DrugCentral uuid:583f750e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.932']} DrugCentral uuid:583f9fd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:583fc8e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:583ff1e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.152']} DrugCentral uuid:58401aea-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:58404484-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:58406d74-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.708']} DrugCentral uuid:5840966e-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5840bfb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:5840e8b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:584111b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.054']} DrugCentral uuid:58413aa6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:584164e0-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:58419046-6b31-11ec-b3df-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Ion channel (Potassium channel subfamily K member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5841b922-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.706']} DrugCentral uuid:5841e226-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:58420bac-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:5842347e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:58425d6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.09']} DrugCentral uuid:58428686-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5842afda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:5842d8d4-6b31-11ec-b3df-0242ac110002 UniProtKB:O00206 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Membrane receptor (Toll-like receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:584302aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:522 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carvedilol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:58432b90-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefacetrile targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:58435282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:584376fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:5843b66e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5843b66e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5843b66e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5843b66e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5843b66e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5843b66e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5843b66e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaclor is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58441a00-6b31-11ec-b3df-0242ac110002 UniProtKB:P46059 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil targets Transporter (Solute carrier family 15 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.14']} DrugCentral uuid:584459a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584459a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584459a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584459a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584459a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584459a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584459a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefadroxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5844bce4-6b31-11ec-b3df-0242ac110002 UniProtKB:P46059 biolink:molecularly_interacts_with DrugCentral:527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole targets Transporter (Solute carrier family 15 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.09']} DrugCentral uuid:5844fe16-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5844fe16-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5844fe16-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5844fe16-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5844fe16-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5844fe16-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5844fe16-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefamandole nafate is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58456284-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:58459dd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58459dd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58459dd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58459dd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58459dd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58459dd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58459dd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefazolin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58460270-6b31-11ec-b3df-0242ac110002 UniProtKB:O54286 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir targets Enzyme (Pencillin binding protein 2a; Penicillin binding protein 2'; Penicillin binding protein, PBP2; Penicillin-binding protein 2; Penicillin-binding protein 2'; Peptidase) DrugCentral uuid:584626f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14TG6 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:58464bd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:58468b82-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58468b82-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58468b82-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58468b82-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58468b82-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58468b82-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58468b82-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5846ef8c-6b31-11ec-b3df-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefdinir targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:58471854-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14TG6 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:58473ce4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q54906 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil targets Enzyme (Penicillin-binding protein) DrugCentral uuid:584778d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584778d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584778d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584778d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584778d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584778d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584778d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefditoren pivoxil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5847f224-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5847f224-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5847f224-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5847f224-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5847f224-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5847f224-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5847f224-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefepime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58485764-6b31-11ec-b3df-0242ac110002 UniProtKB:P42971 biolink:molecularly_interacts_with DrugCentral:536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefetamet pivoxil targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:58487bf4-6b31-11ec-b3df-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefetamet pivoxil targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:5848a070-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5848cc3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:58490c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58490c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58490c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58490c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58490c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58490c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58490c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5849702c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19174 biolink:molecularly_interacts_with DrugCentral:537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefixime targets Enzyme (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5849afba-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5849afba-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5849afba-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5849afba-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5849afba-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5849afba-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5849afba-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmenoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584a12ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:584a4e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584a4e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584a4e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584a4e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584a4e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584a4e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584a4e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584ab1ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:584adad4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefmetazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:584b039c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:584b2d0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:584b5284-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:584b7b56-6b31-11ec-b3df-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:584bbb48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584bbb48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584bbb48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584bbb48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584bbb48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584bbb48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584bbb48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefonicid is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584c1de0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:584c59ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584c59ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584c59ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584c59ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584c59ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584c59ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584c59ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoperazone is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584cbdea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:584cfa80-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584cfa80-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584cfa80-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584cfa80-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584cfa80-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584cfa80-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584cfa80-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceforanide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584d5d18-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:584d85f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.512']} DrugCentral uuid:584daf66-6b31-11ec-b3df-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.659']} DrugCentral uuid:584dd84c-6b31-11ec-b3df-0242ac110002 UniProtKB:B2ZTR6 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:584e0114-6b31-11ec-b3df-0242ac110002 UniProtKB:D6NSM8 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:584e2a18-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotaxime is inhibitor of Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.617']} DrugCentral uuid:584e57c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:584e8094-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:584ea51a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:584ece82-6b31-11ec-b3df-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:584ef772-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:584f204e-6b31-11ec-b3df-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:584f5ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584f5ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584f5ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584f5ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584f5ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584f5ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584f5ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotetan is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:584fc2d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:584fe74a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:585011de-6b31-11ec-b3df-0242ac110002 UniProtKB:P32241 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam targets GPCR (Vasoactive intestinal polypeptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:58505234-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58505234-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58505234-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58505234-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58505234-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58505234-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58505234-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefotiam is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5850b68e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5850db00-6b31-11ec-b3df-0242ac110002 UniProtKB:P00808 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) DrugCentral uuid:5850ff86-6b31-11ec-b3df-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:58512858-6b31-11ec-b3df-0242ac110002 UniProtKB:B2ZTR6 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:585151a2-6b31-11ec-b3df-0242ac110002 UniProtKB:D6NSM8 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:58517a7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5851ba2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5851ba2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5851ba2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5851ba2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5851ba2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5851ba2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5851ba2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefoxitin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:585235b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:585235b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:585235b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:585235b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:585235b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:585235b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:585235b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefpiramide is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:585298e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefprozil targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5852bd8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25098 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Kinase (Beta-adrenergic receptor kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5852e648-6b31-11ec-b3df-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.522']} DrugCentral uuid:58530f88-6b31-11ec-b3df-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.328']} DrugCentral uuid:58533864-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06124 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Enzyme (Tyrosine-protein phosphatase non-receptor type 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5853612c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y468 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Unclassified (Lethal(3)malignant brain tumor-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:585389ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P29350 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Enzyme (Protein-tyrosine phosphatase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5853b410-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5A7N4 biolink:molecularly_interacts_with DrugCentral:558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefsulodin targets Unclassified (tRNA 2'-phosphotransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5853df6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftazidime is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.261']} DrugCentral uuid:58540866-6b31-11ec-b3df-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftazidime is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.534']} DrugCentral uuid:5854314c-6b31-11ec-b3df-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftazidime is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:58545aaa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q1J5W5 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten targets Enzyme (Penicillin-binding protein) DrugCentral uuid:58547f30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60FU1 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:5854bb1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5854bb1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5854bb1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5854bb1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5854bb1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5854bb1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5854bb1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftibuten is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58551f6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:585543de-6b31-11ec-b3df-0242ac110002 UniProtKB:P00808 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime targets Enzyme (Beta-lactamase) DrugCentral uuid:58557fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58557fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58557fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58557fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58557fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58557fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58557fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftizoxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5855e6cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.142']} DrugCentral uuid:58560fc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.513']} DrugCentral uuid:58563956-6b31-11ec-b3df-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.744']} DrugCentral uuid:5856623c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone is inhibitor of Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.213']} DrugCentral uuid:58568b18-6b31-11ec-b3df-0242ac110002 UniProtKB:P14920 biolink:molecularly_interacts_with DrugCentral:564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftriaxone targets Enzyme (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5856b3ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5856d910-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:585701d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:58572a96-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:58576c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58576c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58576c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58576c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58576c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58576c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58576c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:565 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5857e648-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5857e648-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5857e648-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5857e648-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5857e648-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5857e648-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5857e648-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefuroxime axetil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58584a8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:58587360-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:58589d72-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.854']} DrugCentral uuid:5858c662-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.477']} DrugCentral uuid:5858ef5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:58591860-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:5859436c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.917']} DrugCentral uuid:58596c48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:58599524-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5859bde2-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.856']} DrugCentral uuid:5859e736-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:585a0ffe-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:585a38e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:585a63be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:585a8cc2-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:585ab59e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:585ade98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:585b08dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:585b34b0-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:585b5e18-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.033']} DrugCentral uuid:585b86f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:585bb124-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:585bda14-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:585c02dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:585c2be0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:585c5570-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:585c7e42-6b31-11ec-b3df-0242ac110002 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:585ca714-6b31-11ec-b3df-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.32']} DrugCentral uuid:585ccfdc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.627']} DrugCentral uuid:585cfbba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.29']} DrugCentral uuid:585d24b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:585d4d9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8SPQ9 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cyclooxygenase 2; Prostaglandin G/H synthase-2; Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:585d76e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:585d9fb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:585dc8ba-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:585df1aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35355 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:585e1ae0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:585e43c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8HZR1 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:585e6c98-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:585e956a-6b31-11ec-b3df-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:585ec026-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:585ee90c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:585f1206-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:585f3af6-6b31-11ec-b3df-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:585f64d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:585f8db2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:585fb6c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:585fe118-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:58600a08-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:586032e4-6b31-11ec-b3df-0242ac110002 UniProtKB:O78750 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:58605bc0-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:5860860e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5860b246-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:5860db36-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:58610430-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:58612e10-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5861584a-6b31-11ec-b3df-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:58618112-6b31-11ec-b3df-0242ac110002 UniProtKB:O78749 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Cytochrome c oxidase subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5861a9e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:5861d338-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5861fc28-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celecoxib targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:58622504-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celiprolol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:58624e08-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celiprolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:58627a0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 celiprolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5862a2ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P42971 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin targets Enzyme (Penicillin-binding protein 3) DrugCentral uuid:5862c77a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16348 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin targets Transporter (Solute carrier family 15 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:586307da-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:586307da-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:586307da-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:586307da-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:586307da-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:586307da-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:586307da-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalexin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5863814c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5863814c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5863814c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5863814c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5863814c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5863814c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5863814c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefaloglycin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5863e560-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:58640e3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:58643484-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:58645d4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:58648632-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSA0 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Transporter (Solute carrier family 22 member 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5864af0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5864d86c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35236 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin targets Enzyme (Tyrosine-protein phosphatase non-receptor type 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:5865180e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5865180e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5865180e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5865180e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5865180e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5865180e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5865180e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefalotin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58657b3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:5865a40e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5865cce0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5865f59e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:58662172-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:58664a44-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:58667316-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:58669c60-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5866c50a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5866eeea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:58671370-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:58673cc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:5867658c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:58678e54-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5867b74e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5867e28c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:58680e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5868376e-6b31-11ec-b3df-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:58686036-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5868894e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5868b22a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5868f230-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5868f230-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5868f230-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5868f230-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5868f230-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5868f230-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5868f230-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefapirin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:58695586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:58697a02-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5869a2d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5869e398-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5869e398-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5869e398-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5869e398-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5869e398-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5869e398-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5869e398-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefradine is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:586a475c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerivastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:586a6bf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerivastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:586a94d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerivastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:586abdae-6b31-11ec-b3df-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:578 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerulenin targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:586ae720-6b31-11ec-b3df-0242ac110002 UniProtKB:P00488 biolink:molecularly_interacts_with DrugCentral:578 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerulenin targets Enzyme (Coagulation factor XIII A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:586b0ff2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:578 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cerulenin targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:586b38c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceruletide is agonist of GPCR (Cholecystokinin receptor type A) DrugCentral uuid:586b5d54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetirizine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:586b87e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetirizine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:586bb2ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetirizine targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.05']} DrugCentral uuid:586bdbbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetrorelix targets GPCR (Lutropin-choriogonadotropic hormone receptor) DrugCentral uuid:586c0060-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetrorelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:586c29c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.638']} DrugCentral uuid:586c527c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.983']} DrugCentral uuid:586c7b58-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.319']} DrugCentral uuid:586ca416-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.883']} DrugCentral uuid:586ccd7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cevimeline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.201']} DrugCentral uuid:586cf65a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:586d1f2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07339 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets Enzyme (Cathepsin D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.93']} DrugCentral uuid:586d47ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.026']} DrugCentral uuid:586d7468-6b31-11ec-b3df-0242ac110002 UniProtKB:P14091 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets Enzyme (Cathepsin E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.78']} DrugCentral uuid:586da05a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13443 biolink:molecularly_interacts_with DrugCentral:588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorambucil targets Enzyme (Disintegrin and metalloproteinase domain-containing protein 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:586dc940-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:589 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloramphenicol targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:586df24e-6b31-11ec-b3df-0242ac110002 UniProtKB:P62580 biolink:molecularly_interacts_with DrugCentral:589 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloramphenicol targets Enzyme (Chloramphenicol acetyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.89']} DrugCentral uuid:586e1b20-6b31-11ec-b3df-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:589 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloramphenicol targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:586e43d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q88N29 biolink:molecularly_interacts_with DrugCentral:589 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloramphenicol targets Unclassified (Probable HTH-type transcriptional regulator TtgR) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.88']} DrugCentral uuid:586e6db4-6b31-11ec-b3df-0242ac110002 UniProtKB:P10415 biolink:molecularly_interacts_with DrugCentral:593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorcyclizine targets Cytosolic other (Apoptosis regulator Bcl-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.22']} DrugCentral uuid:586e976c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.682']} DrugCentral uuid:586ec066-6b31-11ec-b3df-0242ac110002 UniProtKB:P34981 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:586ee956-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:586f1246-6b31-11ec-b3df-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:586f3ce4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:586f65d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:586f8ec4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21761 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:586fbfe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:586fbfe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:586fbfe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:587008f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:587008f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:587008f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:587051a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:587051a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:587051a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:58709ada-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:58709ada-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:58709ada-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:5870e3a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5870e3a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5870e3a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58715f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58725000-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:58725000-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:58725000-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:58725000-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:58725000-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:58725000-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5872b86a-6b31-11ec-b3df-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5872b86a-6b31-11ec-b3df-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5872f53c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5872f53c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlordiazepoxide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:58732bce-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:587354b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:58737dfe-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5873a6c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5873cfb6-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5873f892-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5874220e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:58744ad6-6b31-11ec-b3df-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:587473b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:58749c98-6b31-11ec-b3df-0242ac110002 UniProtKB:O15056 biolink:molecularly_interacts_with DrugCentral:597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorhexidine targets Enzyme (Synaptojanin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5874c8c6-6b31-11ec-b3df-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5874f1b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.764']} DrugCentral uuid:58751a9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:587543f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:58756cf4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlormadinone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.163']} DrugCentral uuid:58759d78-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomethiazole targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:58759d78-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomethiazole targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:58759d78-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomethiazole targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5875d6e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroprocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:5875fd7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloropyramine targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:58762658-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:58764f52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:58767964-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5876a470-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5876cd60-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5876f74a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5877213e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:58774a38-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5877733c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:58779c2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5877c5c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5877eea2-6b31-11ec-b3df-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5878177e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5878403c-6b31-11ec-b3df-0242ac110002 UniProtKB:P05227 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Cytosolic other (Histidine-rich protein PFHRP-II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:58786b8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P02752 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Unclassified (Riboflavin-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:58789474-6b31-11ec-b3df-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5878bd5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5878e690-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:58790f8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N6S8 biolink:molecularly_interacts_with DrugCentral:607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroquine targets Enzyme (Cysteine proteinase falcipain 2a) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5879385c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorothiazide targets Enzyme (Carbonic anhydrase 2) DrugCentral uuid:58795d32-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['5.43']} DrugCentral uuid:587986a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorotrianisene targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:5879ab48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorotrianisene is modulator of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:5879cfd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5879f8c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:587a22d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18054 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Arachidonate 12-lipoxygenase, 12S-type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:587a4c4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:587a753c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15296 biolink:molecularly_interacts_with DrugCentral:611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxine targets Enzyme (Arachidonate 15-lipoxygenase, type II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:587a9e04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:587ac730-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.818']} DrugCentral uuid:587af00c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.167']} DrugCentral uuid:587b1a00-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:587b42dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:587b6c8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.967']} DrugCentral uuid:587b9566-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.06']} DrugCentral uuid:587bbe4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:587bef84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:587bef84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:587bef84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:587c36d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y468 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Unclassified (Lethal(3)malignant brain tumor-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:587c6004-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96JM7 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Unclassified (Lethal(3)malignant brain tumor-like protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:587c8a0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05BQ5 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Unclassified (MBT domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:587cb36a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:587cdc46-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.842']} DrugCentral uuid:587d0568-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphenamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.975']} DrugCentral uuid:587d2ed0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphentermine is substrate of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.471']} DrugCentral uuid:587d57ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorphentermine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.404']} DrugCentral uuid:587d80c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorproethazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.979']} DrugCentral uuid:587da9be-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorproethazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.987']} DrugCentral uuid:587dd40c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorproethazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:587e0012-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.233']} DrugCentral uuid:587e2b32-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:587e544a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:587e7dda-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:587ea6ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.724']} DrugCentral uuid:587ecfb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:587ef990-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:587f22ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:587f4bf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:587f74ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:587f9eae-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:587fc79e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:587ff08e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:58801960-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:5880430e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:58806c1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.553']} DrugCentral uuid:5880950c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5880bdfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:5880e764-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:5881104a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:58813926-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.759']} DrugCentral uuid:588161ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:58818db8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:5881b95a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.746']} DrugCentral uuid:5881e240-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.251']} DrugCentral uuid:58820b1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:588234b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:58825d92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:58828664-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.827']} DrugCentral uuid:5882afae-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.345']} DrugCentral uuid:5882d89e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:58830292-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:58832b78-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:58835634-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:5883814a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.708']} DrugCentral uuid:5883aa30-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5883d320-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.092']} DrugCentral uuid:5883fcba-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.353']} DrugCentral uuid:58842d52-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.91']} DrugCentral uuid:58842d52-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.91']} DrugCentral uuid:58842d52-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.91']} DrugCentral uuid:58846e2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.133']} DrugCentral uuid:5884976a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.928']} DrugCentral uuid:5884c032-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.463']} DrugCentral uuid:5884e922-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:588511fe-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:58853d64-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.061']} DrugCentral uuid:58856640-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.713']} DrugCentral uuid:58858f12-6b31-11ec-b3df-0242ac110002 UniProtKB:P21817 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Ryanodine receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.569']} DrugCentral uuid:5885b8ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5885e19c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:58860a78-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.043']} DrugCentral uuid:58863368-6b31-11ec-b3df-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:58865d20-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.797']} DrugCentral uuid:58868606-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.305']} DrugCentral uuid:5886aeec-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:5886d8ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.835']} DrugCentral uuid:5887028e-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.146']} DrugCentral uuid:58872b92-6b31-11ec-b3df-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.673']} DrugCentral uuid:58875478-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.777']} DrugCentral uuid:58877d86-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:5887a6da-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5887cfca-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:5887f8a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:588821aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:58884af4-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:588873c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:58889cac-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5888c682-6b31-11ec-b3df-0242ac110002 UniProtKB:O35433 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5888f080-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:58891966-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:58894242-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.854']} DrugCentral uuid:58896bc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5889ac0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5889ac0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5889ac0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5889ac0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5889ac0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5889ac0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5889ac0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:588a353a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:588a353a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:588a353a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:588a353a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:588a353a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:588a353a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:588a353a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:588ab69a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:588ab69a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:588ab69a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:588ab69a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:588ab69a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:588b1310-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:588b1310-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:588b5794-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:588b5794-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:588b5794-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:588b5794-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:588b5794-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:588bb7fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:588bb7fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:588bb7fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:588c0130-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:588c0130-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:588c0130-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:588c5c70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:588c5c70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:588c5c70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:588c5c70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:588c5c70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:588c5c70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:588c5c70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:588c5c70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:588cdcf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:588d05bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:588d2efc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04925 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Unclassified (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:588d57d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P17405 biolink:molecularly_interacts_with DrugCentral:621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpromazine targets Enzyme (Sphingomyelin phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:588d80a0-6b31-11ec-b3df-0242ac110002 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpropamide targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:588dae2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpropamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:588dae2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorpropamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:588de45a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:588e0d68-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.53']} DrugCentral uuid:588e363a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.367']} DrugCentral uuid:588e6236-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:588e8c0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.34']} DrugCentral uuid:588eb506-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:588ede00-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:588f0736-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:588f301c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:588f5902-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:588f829c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:588fac7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:588fd558-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.194']} DrugCentral uuid:588ffe5c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:58902918-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:58905244-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.97']} DrugCentral uuid:58907bb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorprothixene targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5890a4a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortetracycline targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5890cddc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortetracycline targets Surface antigen (Major prion protein) DrugCentral uuid:5890f258-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM07 biolink:molecularly_interacts_with DrugCentral:624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortetracycline targets Enzyme (Protein-arginine deiminase type-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:58911b34-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.56']} DrugCentral uuid:58914424-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:58916972-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5891926c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:5891bb52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5891e460-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:58920e0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:589236ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:58925fe4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:58928924-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5892b214-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:5892db0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:589303fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:625 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlortalidone targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:58932da2-6b31-11ec-b3df-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone is activator of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:58935674-6b31-11ec-b3df-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:58937f46-6b31-11ec-b3df-0242ac110002 UniProtKB:P29475 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, brain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5893a926-6b31-11ec-b3df-0242ac110002 UniProtKB:P29474 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, endothelial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5893d374-6b31-11ec-b3df-0242ac110002 UniProtKB:P29476 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone targets Enzyme (Nitric oxide synthase, brain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.554']} DrugCentral uuid:5893fc6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone is activator of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5894254a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorzoxazone is opener of Ion channel (Calcium-activated potassium channel subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.523']} DrugCentral uuid:58944e12-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:589478a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5894a18c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5894ca7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5894f358-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:58951d10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:589545ec-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:58956ee6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.31']} DrugCentral uuid:589598bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5895c21a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5895eb14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:58961404-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:58963d58-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:589666d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:58968fce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:5896b8be-6b31-11ec-b3df-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:5896e212-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.39']} DrugCentral uuid:58970b52-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:58973474-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:58975d50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:58978924-6b31-11ec-b3df-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5897b34a-6b31-11ec-b3df-0242ac110002 UniProtKB:O96394 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Arginase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5897dc4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:58980520-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4QEW7 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Dihydroorotate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:58982e6a-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:58985750-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:5898805e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:629 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cianidanol targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5898a9ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cibenzoline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5898d2c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cibenzoline targets Ion channel (ATP-sensitive inward rectifier potassium channel 11) DrugCentral uuid:5898f746-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cibenzoline targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:58992022-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:58994a70-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:58997554-6b31-11ec-b3df-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:58999e3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5899c716-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.873']} DrugCentral uuid:5899f07e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.873']} DrugCentral uuid:589a1978-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:589a425e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:589a6b3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicaprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:589a94fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:589ad052-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:589ad052-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:589ad052-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:589ad052-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:589ad052-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:589ad052-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:589ad052-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:589b3718-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclesonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:589b610c-6b31-11ec-b3df-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:636 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclopirox is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:589b89e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:636 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclopirox is inhibitor of Unclassified (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:589bb346-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:636 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclopirox targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:589bdc04-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicloprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:589c04e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cicloprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:589c2dd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cidofovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:589c52d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16444 biolink:molecularly_interacts_with DrugCentral:640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilastatin is inhibitor of Enzyme (Dipeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.959']} DrugCentral uuid:589c7bc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22412 biolink:molecularly_interacts_with DrugCentral:640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilastatin targets Enzyme (Dipeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:589ca4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilazapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:589ccda8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02294 biolink:molecularly_interacts_with DrugCentral:642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilnidipine is blocker of Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:589cfd00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:589cfd00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilnidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:589d2c76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilostazol is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:589d5566-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilostazol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:589d7e4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cilostazol is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:589da7d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:589dd0e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:589df9d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.58']} DrugCentral uuid:589e2342-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:589e4c3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine is inhibitor of Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:589e7554-6b31-11ec-b3df-0242ac110002 UniProtKB:P25102 biolink:molecularly_interacts_with DrugCentral:645 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cimetidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:589e9eda-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinacalcet targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:589ec932-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinacalcet targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:589ef272-6b31-11ec-b3df-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinacalcet is positive allosteric modulator of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:589f1b3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31424 biolink:molecularly_interacts_with DrugCentral:647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinacalcet is allosteric modulator of GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:589f443e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinalukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:589f6ec8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinalukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) DrugCentral uuid:589f9358-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.035']} DrugCentral uuid:589fbc5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:589fe542-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.777']} DrugCentral uuid:58a00eb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:58a037ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.237']} DrugCentral uuid:58a060a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.552']} DrugCentral uuid:58a089a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.208']} DrugCentral uuid:58a0b4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.987']} DrugCentral uuid:58a0de02-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.333']} DrugCentral uuid:58a106fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:58a13050-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:58a15a80-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.064']} DrugCentral uuid:58a1835c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.849']} DrugCentral uuid:58a1ac6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:58a1d5c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:58a1fed6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.292']} DrugCentral uuid:58a227da-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.264']} DrugCentral uuid:58a25174-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:58a27d02-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.885']} DrugCentral uuid:58a2a700-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.242']} DrugCentral uuid:58a2d004-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.299']} DrugCentral uuid:58a2f8f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.793']} DrugCentral uuid:58a3222a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:58a34af2-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.97']} DrugCentral uuid:58a37cac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:58a37cac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:58a37cac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinnarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:58a3bdd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinoxacin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:58a3ea8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:58a3ea8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:58a419aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:58a4443e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AFI2 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.602']} DrugCentral uuid:58a46f72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q45066 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.658']} DrugCentral uuid:58a49844-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin is inhibitor of Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:58a4c12a-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:58a4eaf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin is inhibitor of Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:58a513c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a5757a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:58a657a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:58a657a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Enzyme (DNA topoisomerase II) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:58a68dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P37340 biolink:molecularly_interacts_with DrugCentral:659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciprofloxacin targets Unclassified (Multidrug resistance protein mdtK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.04']} DrugCentral uuid:58a6b714-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:58a6e022-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:58a70912-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:58a731ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:58a75b56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.379']} DrugCentral uuid:58a78464-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.19']} DrugCentral uuid:58a7ad54-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:58a7d63a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:58a8025e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:58a82b76-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:58a85466-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:58a87d7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.396']} DrugCentral uuid:58a8a93e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:58a8d22e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.281']} DrugCentral uuid:58a8fb28-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:58a9251c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.947']} DrugCentral uuid:58a94e0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.155']} DrugCentral uuid:58a97706-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:58a9a0f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.472']} DrugCentral uuid:58a9cc38-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:58a9f5dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.063']} DrugCentral uuid:58aa1ee0-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:58aa47e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:58aa7142-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:58aa9a46-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:58aac32c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:58aaec26-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:58ab158e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:58ab3e9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:58ab6b7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:58ab6b7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:58abb156-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:58abb156-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:58abb156-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:58abb156-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:58abb156-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:58ac159c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:58ac159c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:58ac159c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:58ac159c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:58ac6bbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:58ac6bbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:58ac6bbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:58acb54c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:58acb54c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:58acb54c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:58acf6b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P97288 biolink:molecularly_interacts_with DrugCentral:660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:58ad277a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:661 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisatracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:58ad277a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:661 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisatracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:58ad277a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:661 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisatracurium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:58ad6a00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.777']} DrugCentral uuid:58ad9340-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:58adbc44-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.935']} DrugCentral uuid:58ade566-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:58ae0ec4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.191']} DrugCentral uuid:58ae37f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.931']} DrugCentral uuid:58ae60ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:58ae89f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.456']} DrugCentral uuid:58aeb356-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.875']} DrugCentral uuid:58aedc6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:58af0586-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.148']} DrugCentral uuid:58af2e9e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:58af5b44-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:58af848e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:58afad7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:58afd77c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:58b00080-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:58b0298e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:58b0538c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:58b07ce0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citalopram targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:58b0a5e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q48255 biolink:molecularly_interacts_with DrugCentral:666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citric acid targets Enzyme (3-dehydroquinate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:58b0cede-6b31-11ec-b3df-0242ac110002 UniProtKB:P15474 biolink:molecularly_interacts_with DrugCentral:666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citric acid targets Enzyme (3-dehydroquinate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:58b0f7f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EPK8 biolink:molecularly_interacts_with DrugCentral:666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 citric acid is activator of Ion channel (Transient receptor potential cation channel subfamily V member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:58b1233e-6b31-11ec-b3df-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cladribine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:58b1480a-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cladribine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.441']} DrugCentral uuid:58b170fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cladribine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:58b19a30-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cladribine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.69']} DrugCentral uuid:58b1c38e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:668 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clarithromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:58b1ec88-6b31-11ec-b3df-0242ac110002 UniProtKB:P00807 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'MPC', 'has_quantitative_value': ['8.719']} DrugCentral uuid:58b2158c-6b31-11ec-b3df-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid is inhibitor of Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.187']} DrugCentral uuid:58b23e72-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:58b267c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59401 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:58b290b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD63 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:58b2bae6-6b31-11ec-b3df-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:58b2e552-6b31-11ec-b3df-0242ac110002 UniProtKB:P13661 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase OXA-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:58b311b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:58b33e12-6b31-11ec-b3df-0242ac110002 UniProtKB:A4KCT8 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:58b36806-6b31-11ec-b3df-0242ac110002 UniProtKB:A1E3K9 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:58b3913c-6b31-11ec-b3df-0242ac110002 UniProtKB:A8RR46 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:58b3ba22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6JP75 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Carbapenem-hydrolizing beta-lactamase SFC-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:58b3e312-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9F663 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Carbepenem-hydrolyzing beta-lactamase KPC) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:58b40c02-6b31-11ec-b3df-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:58b435c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EXV5 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:58b45ea0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD64 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:58b4889e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6GWS8 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:58b4b198-6b31-11ec-b3df-0242ac110002 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:58b4db96-6b31-11ec-b3df-0242ac110002 UniProtKB:A0ZX81 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:58b5047c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4TVR4 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:58b52da8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50H31 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Unclassified (Class D beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:58b556fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2XPY6 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:58b57fec-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A3M1 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase SHV-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:58b5a8dc-6b31-11ec-b3df-0242ac110002 UniProtKB:D2SSQ3 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:58b5d1c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3SAW3 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:58b5fb98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q670S6 biolink:molecularly_interacts_with DrugCentral:669 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clavulanic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:58b62492-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:58b64d96-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:58b6769a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:58b6a1a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:58b6cab4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:58b6f3ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:58b71c9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.95']} DrugCentral uuid:58b745fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:58b76f0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:58b79fb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:58b79fb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:58b79fb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:58b7e8ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:58b7e8ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:58b7e8ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clebopride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:58b829ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.115']} DrugCentral uuid:58b853d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:58b87f44-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.161']} DrugCentral uuid:58b8a852-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:58b8d16a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:58b8fa78-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.514']} DrugCentral uuid:58b9250c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.036']} DrugCentral uuid:58b94e38-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:58b97732-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:58b9a0c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:58b9c9bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.848']} DrugCentral uuid:58b9f2ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.604']} DrugCentral uuid:58ba1bd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:58ba45cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:58ba6ec6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:58ba97b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.703']} DrugCentral uuid:58bac0c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.084']} DrugCentral uuid:58baea40-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.558']} DrugCentral uuid:58bb134e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:58bb3c48-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:58bb6556-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.269']} DrugCentral uuid:58bb8f04-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:58bbb808-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:58bbe10c-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:58bc0b82-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:58bc35ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:58bc5fec-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.658']} DrugCentral uuid:58bc89d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:58bcb33e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:58bcdc2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemastine targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:58bd053c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.396']} DrugCentral uuid:58bd2e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23711 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole targets Enzyme (Heme oxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:58bd5802-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBN4 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:58bd8106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:58bda9f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13507 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:58bdd2dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y210 biolink:molecularly_interacts_with DrugCentral:672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clemizole is blocker of Ion channel (Short transient receptor potential channel 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:58bdff00-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.161']} DrugCentral uuid:58be2b4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:58be54c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:58be7e30-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:58bea716-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clenbuterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:58bed038-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:674 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clevidipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:58bef4e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:674 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clevidipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:58bf1a48-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:58bf3f00-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:58bf67dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clindamycin targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:58bf8c80-6b31-11ec-b3df-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:681 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clioquinol targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:58bfb6a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:681 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clioquinol targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:58bfdfb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:681 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clioquinol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:58c009da-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:681 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clioquinol targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:58c03a90-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobazam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:58c03a90-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobazam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:58c03a90-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobazam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:58c075b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05141 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Enzyme (ADP/ATP translocase 2) DrugCentral uuid:58c09a58-6b31-11ec-b3df-0242ac110002 UniProtKB:P12235 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Transporter (ADP/ATP translocase 1) DrugCentral uuid:58c0bede-6b31-11ec-b3df-0242ac110002 UniProtKB:P12236 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Enzyme (ADP/ATP translocase 3) DrugCentral uuid:58c0e378-6b31-11ec-b3df-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) DrugCentral uuid:58c108d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BYT1 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid is inhibitor of Transporter (Solute carrier family 17 member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:58c131ca-6b31-11ec-b3df-0242ac110002 UniProtKB:B1LRJ1 biolink:molecularly_interacts_with DrugCentral:690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clodronic acid targets Unclassified (Type IV secretion-like conjugative transfer relaxase protein TraI) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:58c15ae2-6b31-11ec-b3df-0242ac110002 UniProtKB:P09884 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine is inhibitor of Enzyme (DNA polymerase alpha catalytic subunit) DrugCentral uuid:58c17f9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58c1a95c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58c1d24c-6b31-11ec-b3df-0242ac110002 UniProtKB:P60891 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine targets Kinase (Ribose-phosphate pyrophosphokinase 1) DrugCentral uuid:58c1f6e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HA47 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine targets Kinase (Uridine-cytidine kinase 1) DrugCentral uuid:58c21c02-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BZX2 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine targets Kinase (Uridine-cytidine kinase 2) DrugCentral uuid:58c2410a-6b31-11ec-b3df-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:691 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofarabine targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:58c269f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5L2G3 biolink:molecularly_interacts_with DrugCentral:692 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofazimine targets Enzyme (Uncharacterized oxidoreductase CzcO-like) DrugCentral uuid:58c28e9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:692 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofazimine targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:58c2b7ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:58c2e146-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:58c30a36-6b31-11ec-b3df-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibric acid targets Enzyme (Lipoprotein lipase) DrugCentral uuid:58c32ef8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibric acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:58c357ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofibric acid targets Transcription factor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:58c38380-6b31-11ec-b3df-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clometacin targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58c3ac66-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.461']} DrugCentral uuid:58c3d560-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.455']} DrugCentral uuid:58c3fedc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:58c427d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.745']} DrugCentral uuid:58c450da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:58c47aec-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:58c4a4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:58c4cdc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.025']} DrugCentral uuid:58c4f6de-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.062']} DrugCentral uuid:58c51fe2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:58c54bde-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:58c57640-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.142']} DrugCentral uuid:58c59f4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:58c5c848-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.187']} DrugCentral uuid:58c5f1a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.407']} DrugCentral uuid:58c61ac8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.889']} DrugCentral uuid:58c643b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.358']} DrugCentral uuid:58c66eba-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.638']} DrugCentral uuid:58c697c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.896']} DrugCentral uuid:58c6c0d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.371']} DrugCentral uuid:58c6e9d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.668']} DrugCentral uuid:58c7146e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.206']} DrugCentral uuid:58c73fb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:58c768a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.519']} DrugCentral uuid:58c791d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:58c7bbbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.979']} DrugCentral uuid:58c7e4a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:58c80d9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.778']} DrugCentral uuid:58c83682-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.822']} DrugCentral uuid:58c86030-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:58c88a10-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.597']} DrugCentral uuid:58c8b328-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:58c8dcfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomifene targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:58c9060c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:58c92f06-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:58c9583c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:58c9819a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.243']} DrugCentral uuid:58c9aabc-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.703']} DrugCentral uuid:58c9d3de-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:58c9fcf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:58ca26a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.818']} DrugCentral uuid:58ca4f8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:58ca78ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:58caa1a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.495']} DrugCentral uuid:58cacda2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.337']} DrugCentral uuid:58caf71e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.412']} DrugCentral uuid:58cb202c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.007']} DrugCentral uuid:58cb4912-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.696']} DrugCentral uuid:58cb728e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:58cb9b92-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:58cbc496-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:58cbee62-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:58cc1766-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:58cc4042-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.319']} DrugCentral uuid:58cc6928-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:58cc94d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:58ccbdec-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:58cce704-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:58cd0ff4-6b31-11ec-b3df-0242ac110002 UniProtKB:P09211 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Glutathione S-transferase P) DrugCentral uuid:58cd3510-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:58cd5f4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:58cd884e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.137']} DrugCentral uuid:58cdb15c-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.937']} DrugCentral uuid:58cddba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.4']} DrugCentral uuid:58ce0486-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:58ce2d94-6b31-11ec-b3df-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:58ce5684-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:58ce808c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58ceda6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58cfac32-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:58cfac32-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:58cfac32-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:58cfac32-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:58d0009c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:58d0009c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:58d0009c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:58d04a48-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:58d04a48-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:58d04a48-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:58d08b02-6b31-11ec-b3df-0242ac110002 UniProtKB:P39051 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:58d0b3e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clomipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:58d0e4ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.071']} DrugCentral uuid:58d0e4ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.071']} DrugCentral uuid:58d0e4ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.071']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d15e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:58d253d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d253d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d253d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d253d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d253d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d253d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d2f1da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:58d3cf9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:58d3f972-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:58d4226c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:58d44b98-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:58d4750a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58d49de6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:58d4c6f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:58d4efe4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:58d51960-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:58d54246-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:58d56c6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:58d59570-6b31-11ec-b3df-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:58d5c07c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:58d5ebf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:58d614f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.41']} DrugCentral uuid:58d63e6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:58d667ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:58d690a6-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:58d6b9aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:58d6e2a4-6b31-11ec-b3df-0242ac110002 UniProtKB:O88704 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:58d70c02-6b31-11ec-b3df-0242ac110002 UniProtKB:O88703 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:58d735f6-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.796']} DrugCentral uuid:58d75ee6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:58d79154-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:58d79154-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:58d79154-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:58d7d75e-6b31-11ec-b3df-0242ac110002 UniProtKB:O70507 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:58d80076-6b31-11ec-b3df-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:58d82984-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clonixin targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:58d85274-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloperastine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:58d87b6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clopidogrel targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.524']} DrugCentral uuid:58d8a472-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clopidogrel is antagonist of GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:58d8ce20-6b31-11ec-b3df-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clopidogrel targets Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:58d8fecc-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:58d8fecc-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:58d8fecc-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:58d94724-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:58d94724-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:58d94724-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:58d9890a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:58d9890a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:58d9890a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:58d9ca32-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:58d9ca32-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:58d9ca32-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorazepate is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:58da03da-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.825']} DrugCentral uuid:58da2cde-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:58da56f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:58da7fe0-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:58daa93e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:58dae16a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:58dae16a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:58dae16a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:58dae16a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:58dae16a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:58db45b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:58db45b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:58db45b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotiapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:58db86f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.186']} DrugCentral uuid:58dbaffa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.379']} DrugCentral uuid:58dbd980-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole is antagonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:58dc025c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.136']} DrugCentral uuid:58dc2b88-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.346']} DrugCentral uuid:58dc5482-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.391']} DrugCentral uuid:58dc7dfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.147']} DrugCentral uuid:58dca784-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.351']} DrugCentral uuid:58dcd09c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:58dcf96e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:58dd25ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.174']} DrugCentral uuid:58dd4ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.514']} DrugCentral uuid:58dd77b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.104']} DrugCentral uuid:58dda170-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.995']} DrugCentral uuid:58ddcb96-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:58ddf49a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.132']} DrugCentral uuid:58de1da8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:58de4706-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.235']} DrugCentral uuid:58de7014-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.429']} DrugCentral uuid:58de98fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.046']} DrugCentral uuid:58dec1fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.466']} DrugCentral uuid:58deeda0-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.294']} DrugCentral uuid:58df16fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.781']} DrugCentral uuid:58df3fe4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.287']} DrugCentral uuid:58df68e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.677']} DrugCentral uuid:58df92b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.785']} DrugCentral uuid:58dfbbb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:58dfe4b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.267']} DrugCentral uuid:58e00e1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.353']} DrugCentral uuid:58e03714-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.106']} DrugCentral uuid:58e06018-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.571']} DrugCentral uuid:58e08908-6b31-11ec-b3df-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:58e0b34c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:58e0d840-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.156']} DrugCentral uuid:58e10144-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.521']} DrugCentral uuid:58e12a20-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.132']} DrugCentral uuid:58e153ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.598']} DrugCentral uuid:58e17e12-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:58e1a2a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.756']} DrugCentral uuid:58e1cb9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:58e1f5ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.712']} DrugCentral uuid:58e21f2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:58e24824-6b31-11ec-b3df-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.645']} DrugCentral uuid:58e27182-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:58e29b6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:58e2c452-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.159']} DrugCentral uuid:58e2ed4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:58e31650-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.058']} DrugCentral uuid:58e33ffe-6b31-11ec-b3df-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.089']} DrugCentral uuid:58e368da-6b31-11ec-b3df-0242ac110002 UniProtKB:P22001 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Ion channel (Potassium voltage-gated channel subfamily A member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:58e391ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:58e3bb14-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.497']} DrugCentral uuid:58e3e40e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.178']} DrugCentral uuid:58e40cea-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.854']} DrugCentral uuid:58e435da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:58e4606e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:58e48968-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:58e4b24e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.471']} DrugCentral uuid:58e4db3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.112']} DrugCentral uuid:58e504c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.906']} DrugCentral uuid:58e52ddc-6b31-11ec-b3df-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:58e556b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:58e57fb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.942']} DrugCentral uuid:58e5a94c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:58e5d23c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:58e5fc1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58e6250c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:58e651a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:58e67cf0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.99']} DrugCentral uuid:58e6a5f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:58e6cf2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:58e6f838-6b31-11ec-b3df-0242ac110002 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Transitional endoplasmic reticulum ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:58e7213c-6b31-11ec-b3df-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:58e74a2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPN5 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Putative cytochrome P450 130) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.88']} DrugCentral uuid:58e773d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00766 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Alpha-chymotrypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:58e79cd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:58e7c6be-6b31-11ec-b3df-0242ac110002 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (Transitional endoplasmic reticulum ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:58e7efb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clotrimazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:58e81bc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:58e84490-6b31-11ec-b3df-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:58e86f06-6b31-11ec-b3df-0242ac110002 UniProtKB:A4ZYU9 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:58e8985a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3S5C3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Transporter (Efflux transporter; SugE) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:58e8c140-6b31-11ec-b3df-0242ac110002 UniProtKB:Q48435 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:58e8ea1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P62594 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:58e92270-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:58e92270-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:58e92270-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:58e92270-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:58e92270-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:58e971b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:721 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxazolam targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:58e99a70-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:58e9c36a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.783']} DrugCentral uuid:58e9f038-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:58ea1b80-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:58ea4466-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.154']} DrugCentral uuid:58ea6dc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:58ea96a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:58eabf7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:58eae862-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:58eb11f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:58eb3b0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:58eb63e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:58eb8ce0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:58ebb6ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:58ebdfc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.78']} DrugCentral uuid:58ec08aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:58ec319a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:58ec5ae4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:58ec83de-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.594']} DrugCentral uuid:58ecacce-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:58ecd5b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.815']} DrugCentral uuid:58ecff12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:58ed280c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.181']} DrugCentral uuid:58ed50e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:58ed7a6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.591']} DrugCentral uuid:58eda4e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:58edcdac-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.792']} DrugCentral uuid:58edf796-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.356']} DrugCentral uuid:58ee211c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:58ee4a0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:58ee72fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:58ee9c78-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:58eec702-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:58eeefde-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:58ef18d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:58ef41aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:58ef6d7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22310 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (UDP-glucuronosyltransferase 1-4) {'has_attribute_type': 'IAO:0000004', 'name': 'app Km', 'has_quantitative_value': ['4.208']} DrugCentral uuid:58ef9858-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:58efc15c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:58efeae2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:58f013f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.445']} DrugCentral uuid:58f03cd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:58f065bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:58f08f1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:58f0b814-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:58f0e10e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:58f10a1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:58f134ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:58f15e2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:58f18730-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:58f1b02a-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:58f1d9ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:58f202a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:58f22c6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:58f25570-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:58f27ec4-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:58f2a7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:58f2d07c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:58f2fa2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:58f32310-6b31-11ec-b3df-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:58f34bec-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:58f374c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:58f39e58-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:58f3c766-6b31-11ec-b3df-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:58f3f042-6b31-11ec-b3df-0242ac110002 UniProtKB:P52702 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:58f41928-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:58f4425e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:58f46b80-6b31-11ec-b3df-0242ac110002 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:58f49466-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:58f4be28-6b31-11ec-b3df-0242ac110002 UniProtKB:P50130 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:58f4e920-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:58f51224-6b31-11ec-b3df-0242ac110002 UniProtKB:P52703 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:58f53b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q91ZY2 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:58f5640e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q91ZY1 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:58f59334-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:58f59334-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:58f5d75e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:58f5d75e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:58f5d75e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:58f5d75e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:58f5d75e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:58f63cee-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:58f63cee-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:58f63cee-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:58f63cee-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:58f69144-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:58f69144-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:58f69144-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:58f6d9ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:58f6d9ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:58f71e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:58f71e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:58f71e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:58f71e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:58f71e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:58f77f32-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:58f77f32-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:58f77f32-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:58f7daae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:58f7daae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:58f7daae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:58f7daae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:58f7daae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:58f7daae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:58f7daae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:58f7daae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:58f85fe2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:58f85fe2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:58f85fe2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:58f8a2fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:58f8cc0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:58f8f4f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.21']} DrugCentral uuid:58f91e6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP23 biolink:molecularly_interacts_with DrugCentral:722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clozapine targets Cytosolic other (Calmodulin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:58f9472c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:58f96be4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:58f994f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:58f9be3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:58f9e862-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:58fa1152-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:58fa3a4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.67']} DrugCentral uuid:58fa65d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:58fa8f38-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:58fab832-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:58fae140-6b31-11ec-b3df-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:58fb0ae4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UI33 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel protein type 11 subunit alpha) DrugCentral uuid:58fb2f7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:58fb5864-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16568 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transcription factor (Cocaine- and amphetamine-regulated transcript protein) DrugCentral uuid:58fb7cfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:58fba67a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:58fbcf88-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:58fbf882-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:58fc23a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:58fc4e5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:58fc7b22-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:58fc7b22-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:58fcb876-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:58fcb876-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:58fcb876-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:58fcfa0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P27922 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:58fd2306-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GJT6 biolink:molecularly_interacts_with DrugCentral:723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cocaine targets Transporter (Dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:58fd4bf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:58fd7572-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:58fd9e80-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine is agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:58fdd2ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:58fdd2ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:58fdd2ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:58fdd2ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 codeine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:58fe2076-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:58fe495c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.801']} DrugCentral uuid:58fe7242-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:58fe97a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.49']} DrugCentral uuid:58fec076-6b31-11ec-b3df-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.194']} DrugCentral uuid:58fee966-6b31-11ec-b3df-0242ac110002 UniProtKB:P07437 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine is inhibitor of Structural (Tubulin beta chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:58ff126a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:58ff3bbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P02550 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:58ff64c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6B856 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin beta-2B chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:58ff8dbc-6b31-11ec-b3df-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine is inhibitor of Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:58ffb7ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q27957 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Unclassified (Tubulin polymerization-promoting protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:58ffe30c-6b31-11ec-b3df-0242ac110002 UniProtKB:P68371 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin beta-4B chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:59001840-6b31-11ec-b3df-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:59001840-6b31-11ec-b3df-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:59001840-6b31-11ec-b3df-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:59005d00-6b31-11ec-b3df-0242ac110002 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:59005d00-6b31-11ec-b3df-0242ac110002 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colchicine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:59009310-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08828 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Enzyme (Adenylate cyclase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:5900c3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5900c3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5900c3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:59010520-6b31-11ec-b3df-0242ac110002 UniProtKB:P11166 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Transporter (Solute carrier family 2, facilitated glucose transporter member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:59012e06-6b31-11ec-b3df-0242ac110002 UniProtKB:P19754 biolink:molecularly_interacts_with DrugCentral:729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colforsin daropate targets Enzyme (Adenylate cyclase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:59015714-6b31-11ec-b3df-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan is antagonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:5901802c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:5901a9bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:5901d2c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5901fbb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conivaptan targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:590224be-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:59024e3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Cytosolic other (Annexin A1) DrugCentral uuid:590272ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:59029bce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09470 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:5902c4aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5902ee94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:59031b3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:59031b3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortisone acetate targets Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:59035154-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cortivazol is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:59037706-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:737 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cotinine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:59039dc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5903c6c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5903efb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5904194a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:59044230-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:59046bac-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:590494ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5904be86-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5904e78a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.25']} DrugCentral uuid:59051084-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:59053988-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:59056584-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:59058ed8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5905b7b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:5905e0a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 coumarin targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:59060b06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q33BM1 biolink:molecularly_interacts_with DrugCentral:741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cromoglicic acid targets GPCR (G protein-coupled receptor GPR35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:590633e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES90 biolink:molecularly_interacts_with DrugCentral:741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cromoglicic acid targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:59065df4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cromoglicic acid targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:59068766-6b31-11ec-b3df-0242ac110002 UniProtKB:P25815 biolink:molecularly_interacts_with DrugCentral:741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cromoglicic acid targets Cytosolic other (Protein S100-P) DrugCentral uuid:5906ac0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5906d504-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.237']} DrugCentral uuid:5906fe08-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:59072888-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:590752cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:59077bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5907a4a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.602']} DrugCentral uuid:5907ce14-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:5907f722-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:59082026-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:59084916-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:5908726a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:59089b5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyamemazine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.531']} DrugCentral uuid:5908c454-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.235']} DrugCentral uuid:5908ed4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:5909179c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.623']} DrugCentral uuid:590940a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.272']} DrugCentral uuid:590969a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.993']} DrugCentral uuid:590993c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.353']} DrugCentral uuid:5909bca6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.788']} DrugCentral uuid:5909e5aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.385']} DrugCentral uuid:590a0ea4-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.799']} DrugCentral uuid:590a3802-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.924']} DrugCentral uuid:590a60fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.342']} DrugCentral uuid:590a8a00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:590ab30e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.206']} DrugCentral uuid:590adef6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:590b0868-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:590b2d0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclizine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:590b571e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.728']} DrugCentral uuid:590b8068-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:590ba962-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:590bd270-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.541']} DrugCentral uuid:590bfb60-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.812']} DrugCentral uuid:590c24dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:590c4dd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:590c76d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:590ca15a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.829']} DrugCentral uuid:590ccb62-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:590cf448-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:590d1e6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.222']} DrugCentral uuid:590d47e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.509']} DrugCentral uuid:590d70c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclobenzaprine targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:590d99c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclofenil targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:590dc2b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclofenil targets Nuclear other (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:590debdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:590e14ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:590e3df8-6b31-11ec-b3df-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil is inhibitor of Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:590e66fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:590e90e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:590eb9ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P00378 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:590ee30c-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloguanil targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:590f0c74-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclopentolate is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:590f310e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclophosphamide targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:590f5ada-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:590f83b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:590fad00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:590fd65e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:590fff44-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:591028b6-6b31-11ec-b3df-0242ac110002 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5910539a-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WQA8 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Enzyme (Alanine racemase) DrugCentral uuid:591079a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05586 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5910a278-6b31-11ec-b3df-0242ac110002 UniProtKB:O60391 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5910cb72-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WP31 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine is inhibitor of Enzyme (D-alanine--D-alanine ligase) DrugCentral uuid:5910f098-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WQA9 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine is inhibitor of Enzyme (Alanine racemase) DrugCentral uuid:59111528-6b31-11ec-b3df-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:59113e04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00961 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:59117dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:59117dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:59117dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:59117dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:59117dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:59117dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:59117dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycloserine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5911ee58-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5912175c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:59124470-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:59126df6-6b31-11ec-b3df-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:59129704-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5912c062-6b31-11ec-b3df-0242ac110002 UniProtKB:P62937 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is modulator of Enzyme (Peptidyl-prolyl cis-trans isomerase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.046']} DrugCentral uuid:5912ea60-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5913133c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:59133c18-6b31-11ec-b3df-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is antagonist of GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5913667a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:59138f74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:5913b88c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02790 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5913e15e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:59140ddc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23284 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.01']} DrugCentral uuid:59143a28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:591463cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:59148d2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P68106 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5914b62e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08752 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Enzyme (Peptidyl-prolyl cis-trans isomerase D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5914df32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPD5 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:59150822-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin is inhibitor of Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:59153144-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:59155a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JHG7 biolink:molecularly_interacts_with DrugCentral:760 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciclosporin targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:59158310-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:5915a7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P42261 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5915d252-6b31-11ec-b3df-0242ac110002 UniProtKB:P42262 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:5915fb38-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide is allosteric modulator of Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:59162432-6b31-11ec-b3df-0242ac110002 UniProtKB:P42263 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide is allosteric modulator of Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:59165858-6b31-11ec-b3df-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:59165858-6b31-11ec-b3df-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:59165858-6b31-11ec-b3df-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:59165858-6b31-11ec-b3df-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclothiazide targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5916a74a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19838 biolink:molecularly_interacts_with DrugCentral:762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclovalone targets Cytosolic other (Nuclear factor NF-kappa-B p105 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5916d026-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclovalone targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5916f984-6b31-11ec-b3df-0242ac110002 UniProtKB:P05412 biolink:molecularly_interacts_with DrugCentral:762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclovalone targets Transcription factor (Transcription factor AP-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:591722c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cycrimine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5917474a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.932']} DrugCentral uuid:59177026-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:59179a7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:5917c486-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.855']} DrugCentral uuid:5917ed6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:59181210-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:59183b6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:59186468-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:59188d62-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.419']} DrugCentral uuid:5918b652-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.812']} DrugCentral uuid:5918dfb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.652']} DrugCentral uuid:5919088c-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:59193186-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:59195a80-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:59198654-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5919af9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:5919d9d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.222']} DrugCentral uuid:591a02d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:591a2c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.185']} DrugCentral uuid:591a553e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:591a7e24-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:591aa796-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:591ad180-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:591afa8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.559']} DrugCentral uuid:591b2392-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.886']} DrugCentral uuid:591b4e8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.733']} DrugCentral uuid:591b7a72-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:591ba3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:591bd44a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Cytosolic other (Calmodulin) DrugCentral uuid:591bd44a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Cytosolic other (Calmodulin) DrugCentral uuid:591bd44a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Cytosolic other (Calmodulin) DrugCentral uuid:591c0e1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:591c371e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.899']} DrugCentral uuid:591c6004-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:591c89e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:591cb2e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:591cdbd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:591d04aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:591d2fde-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:591d58e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:591d81e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P34968 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:591daae0-6b31-11ec-b3df-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:591dd448-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:591dfd2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:591e356e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:591e356e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:591e356e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:591e356e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:591e356e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:591e9f36-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:591e9f36-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:591e9f36-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:591e9f36-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:591e9f36-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:591f020a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:591f020a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:591f020a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:591f4b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:591f4b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:591f4b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:591f8e0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WTS6 biolink:molecularly_interacts_with DrugCentral:765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproheptadine targets Enzyme (Histone-lysine N-methyltransferase SETD7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:591fb704-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.053']} DrugCentral uuid:591fe008-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:592008f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.432']} DrugCentral uuid:5920322e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.678']} DrugCentral uuid:59205b0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:592083e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.315']} DrugCentral uuid:5920acc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyproterone acetate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5920d8a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPY5 biolink:molecularly_interacts_with DrugCentral:769 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cysteine targets Transporter (Cystine/glutamate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:59210348-6b31-11ec-b3df-0242ac110002 UniProtKB:P15309 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine targets Enzyme (Prostatic acid phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'GI50', 'has_quantitative_value': ['7']} DrugCentral uuid:59212c4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:59215546-6b31-11ec-b3df-0242ac110002 UniProtKB:P06746 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine targets Enzyme (DNA polymerase beta) DrugCentral uuid:59218200-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:59218200-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:59218200-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:5921bc98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00987 biolink:molecularly_interacts_with DrugCentral:770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytarabine targets Nuclear other (E3 ubiquitin-protein ligase Mdm2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5921e57e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacarbazine targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.255']} DrugCentral uuid:59220ed2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14181 biolink:molecularly_interacts_with DrugCentral:773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacarbazine targets Enzyme (DNA polymerase alpha subunit B) DrugCentral uuid:5922336c-6b31-11ec-b3df-0242ac110002 UniProtKB:P62993 biolink:molecularly_interacts_with DrugCentral:774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dactinomycin targets Cytosolic other (Growth factor receptor-bound protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:59225c2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dactinomycin targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:59228510-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60631 biolink:molecularly_interacts_with DrugCentral:774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dactinomycin targets Cytosolic other (Growth factor receptor-bound protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5922b044-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96IV0 biolink:molecularly_interacts_with DrugCentral:774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dactinomycin targets Enzyme (Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.05']} DrugCentral uuid:5922d9fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:592302ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:59232be6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:5923554e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:59237e52-6b31-11ec-b3df-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.34']} DrugCentral uuid:5923a756-6b31-11ec-b3df-0242ac110002 UniProtKB:P04070 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Vitamin K-dependent protein C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5923d0c8-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5923f9b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:592422a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:59245322-6b31-11ec-b3df-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:59245322-6b31-11ec-b3df-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:59245322-6b31-11ec-b3df-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5924963e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:5924bf24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28731 biolink:molecularly_interacts_with DrugCentral:776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabigatran etexilate targets Unclassified (Thrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5924e80a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.243']} DrugCentral uuid:59251186-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:59253a8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.163']} DrugCentral uuid:59256488-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.087']} DrugCentral uuid:59258d8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.248']} DrugCentral uuid:5925b80c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.597']} DrugCentral uuid:5925e11a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.976']} DrugCentral uuid:59260a0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.009']} DrugCentral uuid:59263322-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.425']} DrugCentral uuid:59265f78-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.708']} DrugCentral uuid:59268886-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.894']} DrugCentral uuid:5926b16c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.462']} DrugCentral uuid:5926dade-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.265']} DrugCentral uuid:592703ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:59272cbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.207']} DrugCentral uuid:592755ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.294']} DrugCentral uuid:59277f0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:5927a3b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:5927c840-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:5927f0fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Enzyme (Steryl-sulfatase) DrugCentral uuid:5928170a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:59284040-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.053']} DrugCentral uuid:59286958-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:592892c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 danazol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:5928bc3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21817 biolink:molecularly_interacts_with DrugCentral:780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dantrolene is antagonist of Ion channel (Ryanodine receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.757']} DrugCentral uuid:5928e536-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15413 biolink:molecularly_interacts_with DrugCentral:780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dantrolene is antagonist of Ion channel (Ryanodine receptor 3) DrugCentral uuid:592909da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dantrolene targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:592932d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.929']} DrugCentral uuid:59295c50-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.762']} DrugCentral uuid:5929863a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:5929af3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.485']} DrugCentral uuid:5929d84c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole is antagonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5929fdd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.279']} DrugCentral uuid:592a26e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.388']} DrugCentral uuid:592a4fd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:592a7450-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:592a9df4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:592ac6bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:592aefac-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:592b18b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:592b4222-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C0X1 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone is inhibitor of Enzyme (Dihydropteroate synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:592b6b26-6b31-11ec-b3df-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:592b940c-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:592bbdf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:592be358-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4Z710 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Unclassified (Dihydropteroate synthetase, putative) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:592c0c3e-6b31-11ec-b3df-0242ac110002 UniProtKB:A0A113T0T6 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Unclassified (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:592c3524-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapsone targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:592c5f72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q57P83 biolink:molecularly_interacts_with DrugCentral:783 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daptomycin targets Transporter (Outer membrane porin protein OmpD) DrugCentral uuid:592c8538-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:592cae28-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:592cd722-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:592d004e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:592d293e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:592d5260-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:592d7b50-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:592da5ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:592dcef2-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:592df7e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darifenacin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:592e20dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:592e4a94-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:592e7410-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.6']} DrugCentral uuid:592e9d14-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:592ec690-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:592eefc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:592f188e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Breakpoint cluster region protein) DrugCentral uuid:592f3d5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:592f674e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:592f93a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:592fbe88-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.1']} DrugCentral uuid:592fe78c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.07']} DrugCentral uuid:5930113a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:59303a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5930631a-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:59308bf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5930b554-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5930de44-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5931072a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:59313006-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.33']} DrugCentral uuid:59315b08-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:593183e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5931ae00-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.46']} DrugCentral uuid:5931d79a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:59320094-6b31-11ec-b3df-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:59322998-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:59325274-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:59327baa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5932a4c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5932cd94-6b31-11ec-b3df-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.62']} DrugCentral uuid:5932f68e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:59332096-6b31-11ec-b3df-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.85']} DrugCentral uuid:59334abc-6b31-11ec-b3df-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:593373ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:59339c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5933c622-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5933eef4-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.77']} DrugCentral uuid:593417e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15759 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:593440ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.62']} DrugCentral uuid:59346a1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.92']} DrugCentral uuid:59349322-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5934bc08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5934e5e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:59351018-6b31-11ec-b3df-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:59353912-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:59356284-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.03']} DrugCentral uuid:59358c00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5935b5c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.03']} DrugCentral uuid:5935deb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:593607ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.51']} DrugCentral uuid:59363132-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:59365a18-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:593682f4-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.59']} DrugCentral uuid:5936abe4-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5936d68c-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.35']} DrugCentral uuid:5936ff72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:59372862-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.25']} DrugCentral uuid:59375152-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:59377af6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.16']} DrugCentral uuid:5937a3dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.47']} DrugCentral uuid:5937ccc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5937f616-6b31-11ec-b3df-0242ac110002 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:59381f10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:593847f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:593870dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:59389a76-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5938c366-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5938ec56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:5939153c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06240 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Proto-oncogene tyrosine-protein kinase LCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.19']} DrugCentral uuid:59393ee0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.85']} DrugCentral uuid:593967e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:59399106-6b31-11ec-b3df-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.41']} DrugCentral uuid:5939bb22-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5939e48a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:593a0d7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:593a3796-6b31-11ec-b3df-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:593a611c-6b31-11ec-b3df-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:593a8a66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:593ab36a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.68']} DrugCentral uuid:593adc5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:593b069e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:593b316e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:593b5a72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:593b8362-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.19']} DrugCentral uuid:593bacde-6b31-11ec-b3df-0242ac110002 UniProtKB:P27037 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activin receptor type-2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:593bd5ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13705 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Activin receptor type-2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:593bfec8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:593c2830-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:593c51de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:593c7ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:593ca3b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6DT37 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase MRCK gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:593cccae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:593cf620-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99640 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:593d1f10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:593d47ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:593d7186-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:593d9a76-6b31-11ec-b3df-0242ac110002 UniProtKB:P36894 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Bone morphogenetic protein receptor type-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:593dc4c4-6b31-11ec-b3df-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:593dedbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5VT25 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase MRCK alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:593e182a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:593e4340-6b31-11ec-b3df-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:593e6c26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib is inhibitor of Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:593e9520-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:593ebe92-6b31-11ec-b3df-0242ac110002 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:593ee76e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.39']} DrugCentral uuid:593f105e-6b31-11ec-b3df-0242ac110002 UniProtKB:P54753 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.16']} DrugCentral uuid:593f394e-6b31-11ec-b3df-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:593f62de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:593f8bc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:593fb4aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P16277 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:593fdd90-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.41']} DrugCentral uuid:5940077a-6b31-11ec-b3df-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:59403074-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:594059a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:594082fe-6b31-11ec-b3df-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5940abd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5940d4c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5940fedc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:59412876-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:59415166-6b31-11ec-b3df-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:59417a42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5941a332-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5941cfc4-6b31-11ec-b3df-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:5941f8fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:594221ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:59424ad0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86Y07 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase VRK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:59427424-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:59429d14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.48']} DrugCentral uuid:5942c618-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NG66 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Serine/threonine-protein kinase Nek11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:5942f03e-6b31-11ec-b3df-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5943248c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5943248c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5943248c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5943248c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (MAP kinase p38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:594374f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase; MEK1/2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:594374f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase; MEK1/2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5943b064-6b31-11ec-b3df-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5943b064-6b31-11ec-b3df-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5943e55c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01538 biolink:molecularly_interacts_with DrugCentral:785 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasatinib targets Transcription factor (Myelin transcription factor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:59440e38-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:59443340-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:594457d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:59447c56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:5944a0d2-6b31-11ec-b3df-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:5944c60c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5944efe2-6b31-11ec-b3df-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicin targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:594518a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deanol targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:5945419a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28570 biolink:molecularly_interacts_with DrugCentral:787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deanol targets Transporter (Creatine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:59456d50-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:788 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 debrisoquine targets Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:59459280-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:788 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 debrisoquine targets Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:5945b7d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:5945e0be-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:59460a08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:594632e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:59465fbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:59465fbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5946a4f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:5946a4f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:5946a4f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:5946a4f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:5946a4f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:789 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decamethonium is partial agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:5946f49a-6b31-11ec-b3df-0242ac110002 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:790 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decitabine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:59471d9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:790 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 decitabine is inhibitor of Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:594743a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:792 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deferoxamine targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:59476c68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:792 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deferoxamine targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5947954e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5947be84-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.84']} DrugCentral uuid:5947e7d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasterone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:594810be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GRG7 biolink:molecularly_interacts_with DrugCentral:795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasterone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:594839b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.921']} DrugCentral uuid:594862a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.97']} DrugCentral uuid:59488c2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.276']} DrugCentral uuid:5948b51e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:5948ddfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5949079e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:594932e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:59495bc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delavirdine targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:59498cf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:59498cf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:59498cf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594a068a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delorazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:594ae4a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demecarium is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:594b0940-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A7V8 biolink:molecularly_interacts_with DrugCentral:802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demeclocycline targets Ribosomal protein (30S ribosomal protein S4) DrugCentral uuid:594b2dd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A7X3 biolink:molecularly_interacts_with DrugCentral:802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demeclocycline targets Ribosomal protein (30S ribosomal protein S9) DrugCentral uuid:594b526a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demeclocycline targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:594b7c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denopamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:594ba58a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denopamine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:594bcfa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P58154 biolink:molecularly_interacts_with DrugCentral:808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deptropine targets Unclassified (Acetylcholine-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:594bf8aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WSF8 biolink:molecularly_interacts_with DrugCentral:808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deptropine targets Unclassified (Soluble acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:594c29ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desalkylflurazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:594c29ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desalkylflurazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:594c29ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desalkylflurazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:594c6ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deserpidine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:594c8f68-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:594cb4f2-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:594cd98c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:594cfed0-6b31-11ec-b3df-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:594d237e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:594d4c0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:594d4c0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594db3de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:594e7558-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:594ea0d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.631']} DrugCentral uuid:594eca1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:594ef302-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:594f1be8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.755']} DrugCentral uuid:594f4546-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.081']} DrugCentral uuid:594f6e40-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.194']} DrugCentral uuid:594f971c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:594fc0ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:594fe97e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:59501246-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:59503b0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:595060d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:59508c1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:5950b64c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:5950dfc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:59510912-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:595131f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.84']} DrugCentral uuid:59515aca-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:595183c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:5951ad54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:5951d202-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:5951fae8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.6']} DrugCentral uuid:595223c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:59524ee4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:595277de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.19']} DrugCentral uuid:5952a0ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5952c9b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:5952f2ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:59531bc6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5953767a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:59544320-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:59544320-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:59544320-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:595483f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5954ad56-6b31-11ec-b3df-0242ac110002 UniProtKB:P48545 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5954d74a-6b31-11ec-b3df-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:59551ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:59551ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:59551ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:59551ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:59551ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:59551ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:59551ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:59551ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deslanoside is inhibitor of Transporter (Sodium/potassium-transporting ATPase) DrugCentral uuid:59558b18-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:5955b408-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.914']} DrugCentral uuid:5955de56-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.956']} DrugCentral uuid:59560778-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.025']} DrugCentral uuid:59563086-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:59565994-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:595682fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.997']} DrugCentral uuid:5956abf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.009']} DrugCentral uuid:5956d50e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.189']} DrugCentral uuid:5956fe08-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:595727c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.967']} DrugCentral uuid:59575150-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:59577a40-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5957a344-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5957ce78-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:5957f77c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:59582080-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:595849de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.511']} DrugCentral uuid:595873e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desloratadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.698']} DrugCentral uuid:59589d1c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75899 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets GPCR (Gamma-aminobutyric acid type B receptor subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.027']} DrugCentral uuid:5958c5f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28476 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit rho-2) DrugCentral uuid:5958f2ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.284']} DrugCentral uuid:5958f2ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.284']} DrugCentral uuid:5958f2ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.284']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59596878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:595a44dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:595a6dd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:595a9806-6b31-11ec-b3df-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin is agonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:595ac1aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.01']} DrugCentral uuid:595aeb80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:595b1466-6b31-11ec-b3df-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.97']} DrugCentral uuid:595b3d60-6b31-11ec-b3df-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:595b6862-6b31-11ec-b3df-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desmopressin is agonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:595b93aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desogestrel is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:595bb844-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desogestrel targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:595be13e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoximetasone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.932']} DrugCentral uuid:595c0a92-6b31-11ec-b3df-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoximetasone targets Cytosolic other (Annexin A1) DrugCentral uuid:595c2f22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoximetasone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:595c5876-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.854']} DrugCentral uuid:595c8148-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.498']} DrugCentral uuid:595caaf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:595cd3dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:595cfce0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11']} DrugCentral uuid:595d25b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:595d526c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycortone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:595d7ca6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycorticosterone acetate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) DrugCentral uuid:595da14a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desoxycorticosterone pivalate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:595dca94-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.886']} DrugCentral uuid:595df384-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.88']} DrugCentral uuid:595e1c4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Cytosolic other (Annexin A1) DrugCentral uuid:595e40d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:595e6a1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:595e92d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P05112 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Cytokine (Interleukin-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.33']} DrugCentral uuid:595ebc24-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:595ee500-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:595f0fee-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.786']} DrugCentral uuid:595f38de-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:595f61c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.517']} DrugCentral uuid:595f8abe-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:595fb444-6b31-11ec-b3df-0242ac110002 UniProtKB:O54915 biolink:molecularly_interacts_with DrugCentral:824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:595fdd0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:59600192-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:59602a78-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:596053a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:59607cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5960a58e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:5960ce74-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5960f818-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:596120ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone palmitate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:59614ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:59617496-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:59619d5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5961c644-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5961ef20-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:59621856-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:59624146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:59626a2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone valerate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:59629312-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexbrompheniramine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5962b978-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:5962e3a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:59631bd4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:59631bd4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:59631bd4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:59631bd4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:59631bd4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexetimide targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:59637552-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.002']} DrugCentral uuid:59639e4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:5963c750-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.664']} DrugCentral uuid:5963f09a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.176']} DrugCentral uuid:59641994-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:5964428e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.607']} DrugCentral uuid:59646b74-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.384']} DrugCentral uuid:596496da-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5964bfc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.042']} DrugCentral uuid:5964e8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.257']} DrugCentral uuid:596511a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:59653b26-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:596563ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.733']} DrugCentral uuid:59658cde-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.577']} DrugCentral uuid:5965b5c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.326']} DrugCentral uuid:5965defa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.156']} DrugCentral uuid:596607d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:596630c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.898']} DrugCentral uuid:59665b8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.706']} DrugCentral uuid:5966888c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.848']} DrugCentral uuid:5966b154-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfenfluramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5966da4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:833 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:596703de-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:833 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:59672cc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexloxiglumide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:596755b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:59677e7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5967a802-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5967d23c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5967fb2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:5968241c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:596850f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:59687d86-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5968ae6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:5968ae6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:5968ae6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:5968f7d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5968f7d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5968f7d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5969388e-6b31-11ec-b3df-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmedetomidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:596961e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:59698690-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5969af6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.13']} DrugCentral uuid:5969d85c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:596a1236-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:596a1236-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:596a1236-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:596a1236-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:596a1236-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexmethylphenidate targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:596a6c04-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:596a94ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:596abe8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:596ae788-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:596b106e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:596b39cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:596b62da-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:596b8c60-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:596bb55a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.824']} DrugCentral uuid:596bdfe4-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:596c08de-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:596c31d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:596c5ac8-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:596c84bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:596cadac-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.42']} DrugCentral uuid:596cde3a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:596cde3a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:596cde3a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:596d23cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:596d23cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexniguldipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:596d52a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:596d7868-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:596da270-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:596dcc78-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:596df568-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:596e1a0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine is releasing agent of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:596e434c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16568 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Transcription factor (Cocaine- and amphetamine-regulated transcript protein) DrugCentral uuid:596e67e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:596e90e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:596eb57a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.87']} DrugCentral uuid:596edeba-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:596f07c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:596f309a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:596f599e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:596f83c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:596fae6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970084e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5970cebe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan is agonist of Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'D2', 'has_quantitative_value': ['6.458']} DrugCentral uuid:5970f7a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.842']} DrugCentral uuid:597120a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ks', 'has_quantitative_value': ['4.48']} DrugCentral uuid:597149c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan is antagonist of Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:59717382-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan is blocker of Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:59719c7c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5971c56c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5971eede-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:59722e80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:59722e80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:59722e80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:59722e80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:59722e80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:59722e80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:59722e80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:5972a8ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5972a8ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5972a8ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5972e9ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:59731390-6b31-11ec-b3df-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextromethorphan targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:59733e9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:844 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextropropoxyphene targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:59736336-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:844 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextropropoxyphene is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:597387da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:844 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextropropoxyphene targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5973b1c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:5973df3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor) DrugCentral uuid:5973df3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor) DrugCentral uuid:59742514-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:59742514-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:59742514-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:59742514-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:59742514-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:59742514-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:59742514-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dextrothyroxine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:59749684-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dezocine is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5974bf7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dezocine is antagonist of GPCR (Kappa-type opioid receptor) DrugCentral uuid:5974e44a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42574 biolink:molecularly_interacts_with DrugCentral:849 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diacerein targets Enzyme (Caspase-3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:59750f60-6b31-11ec-b3df-0242ac110002 UniProtKB:P55210 biolink:molecularly_interacts_with DrugCentral:849 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diacerein targets Enzyme (Caspase-7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:59753a62-6b31-11ec-b3df-0242ac110002 UniProtKB:Q17339 biolink:molecularly_interacts_with DrugCentral:849 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diacerein targets Unclassified (Female germline-specific tumor suppressor gld-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5975635c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02083 biolink:molecularly_interacts_with DrugCentral:849 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diacerein targets Enzyme (N-acylethanolamine-hydrolyzing acid amidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:597593f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:597593f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:597593f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:5975d530-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5975fe34-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:59762738-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is allosteric modulator of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:597650c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:59767a44-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:5976a3ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5976ceb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:5976f8b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:597721ba-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:59774aa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.67']} DrugCentral uuid:597773f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:59779cda-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:5977c5e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P62813 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5977eed8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23576 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:597819b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P19969 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:59784a40-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.143']} DrugCentral uuid:59784a40-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.143']} DrugCentral uuid:59784a40-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.143']} DrugCentral uuid:597892ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:597892ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:597892ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:5978dcbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:5978dcbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:5978dcbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:59792564-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:59792564-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:59792564-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:59796e8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.705']} DrugCentral uuid:59796e8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.705']} DrugCentral uuid:59796e8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.705']} DrugCentral uuid:5979b876-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:5979b876-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:5979b876-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597a3274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:597b2418-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:597b2418-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:597b2418-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:597b2418-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:597b2418-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:597b2418-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:597b9182-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:597b9182-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:597b9182-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:597bdbf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:597bdbf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:597bdbf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:597c2476-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:597c2476-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:597c2476-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597c9c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0Y8 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:597d752e-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:597d752e-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:597d752e-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:597dbe58-6b31-11ec-b3df-0242ac110002 UniProtKB:P63079 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:597dbe58-6b31-11ec-b3df-0242ac110002 UniProtKB:P63079 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:597dbe58-6b31-11ec-b3df-0242ac110002 UniProtKB:P63079 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:597e070a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:597e070a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:597e070a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.939']} DrugCentral uuid:597e5426-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.665']} DrugCentral uuid:597e5426-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.665']} DrugCentral uuid:597e5426-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.665']} DrugCentral uuid:597e9cb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:597e9cb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:597e9cb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:597ee666-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:597ee666-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:597ee666-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.004']} DrugCentral uuid:597f2752-6b31-11ec-b3df-0242ac110002 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazoxide targets Enzyme (Nicotinamide phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.64']} DrugCentral uuid:597f543e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazoxide is opener of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:597f543e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazoxide is opener of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:597f8b16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61743 biolink:molecularly_interacts_with DrugCentral:854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diazoxide is activator of Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:597fb3d4-6b31-11ec-b3df-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibekacin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.921']} DrugCentral uuid:597fde0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:59800352-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:59802fa8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:59802fa8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:59802fa8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5980706c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:598099de-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazone is blocker of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.081']} DrugCentral uuid:5980c2e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15118 biolink:molecularly_interacts_with DrugCentral:862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3']} DrugCentral uuid:5980ebfa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15119 biolink:molecularly_interacts_with DrugCentral:862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.699']} DrugCentral uuid:59811508-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15120 biolink:molecularly_interacts_with DrugCentral:862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.097']} DrugCentral uuid:59813eca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16654 biolink:molecularly_interacts_with DrugCentral:862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichloroacetic acid is inhibitor of Kinase ([Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.301']} DrugCentral uuid:598167c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorophen targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:598190a0-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorophen targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5981b986-6b31-11ec-b3df-0242ac110002 UniProtKB:P11021 biolink:molecularly_interacts_with DrugCentral:863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorophen targets Unclassified (78 kDa glucose-regulated protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5981e46a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:59820d78-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:59823672-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:59825f94-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.602']} DrugCentral uuid:598288ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:5982b1c4-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:5982dad2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:59830462-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:59832d52-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide is inhibitor of Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.577']} DrugCentral uuid:59835638-6b31-11ec-b3df-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.423']} DrugCentral uuid:5983800e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5983aa34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5983d324-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5983fc28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5984250e-6b31-11ec-b3df-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:59844e76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:598477f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5984a100-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:5984c9dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5984f38a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:59851c70-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5985456a-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:59856e46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5985990c-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5985c210-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5985eaf6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:59861594-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:59863eac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:598667a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:598690a0-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dichlorphenamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:5986ba26-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5986e316-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:59870be8-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:598734ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:59875f6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is antagonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5987897e-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5987b26e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5987db54-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:59880480-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:59882d70-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:59885642-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:59887f14-6b31-11ec-b3df-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5988a886-6b31-11ec-b3df-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5988d18a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is blocker of Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5988fa70-6b31-11ec-b3df-0242ac110002 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:598924a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22309 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:59894e94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HAW7 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:598977a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P19224 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5989a0b0-6b31-11ec-b3df-0242ac110002 UniProtKB:O60656 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5989ca0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HAW8 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Enzyme (UDP-glucuronosyltransferase 1-10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5989f380-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCF6 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:598a1cde-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diclofenac targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:598a459c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:598a6f18-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:598a97e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:598ac0b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:598ae984-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:598b113e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:598b3a56-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:598b633c-6b31-11ec-b3df-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:598b8d12-6b31-11ec-b3df-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:598bc55c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:598bc55c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:598bc55c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:598bc55c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:598bc55c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicloxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:598c1336-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.971']} DrugCentral uuid:598c3cc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P15559 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (NAD(P)H dehydrogenase [quinone] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:598c66e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.388']} DrugCentral uuid:598c8fc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.354']} DrugCentral uuid:598cb8b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16549 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Proprotein convertase subtilisin/kexin type 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:598ce464-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:598d0d72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:598d3644-6b31-11ec-b3df-0242ac110002 UniProtKB:P07374 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (Urease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:598d5f48-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WMN1 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (ATP phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:598d889c-6b31-11ec-b3df-0242ac110002 UniProtKB:P05982 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol targets Enzyme (NULLD(P)H dehydrogenase [quinone] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:598db1aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicoumarol is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.509']} DrugCentral uuid:598dda90-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.686']} DrugCentral uuid:598e042a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.773']} DrugCentral uuid:598e2d2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.161']} DrugCentral uuid:598e5628-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.082']} DrugCentral uuid:598e7f22-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.611']} DrugCentral uuid:598ea8e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.847']} DrugCentral uuid:598ed1de-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.386']} DrugCentral uuid:598eface-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:598f23e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.079']} DrugCentral uuid:598f4f06-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:598f7828-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.033']} DrugCentral uuid:598fa12c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.386']} DrugCentral uuid:598fca26-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.767']} DrugCentral uuid:598ff456-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.327']} DrugCentral uuid:59901d3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P70676 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Unclassified (SMR1-alpha2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:59904622-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:59906f08-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.61']} DrugCentral uuid:5990a07c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5990a07c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5990a07c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dicycloverine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5990e190-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72549 biolink:molecularly_interacts_with DrugCentral:869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 didanosine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:59910a8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dienestrol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:599133ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dienogest is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:59915882-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:5991812c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylcarbamazine targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:5991a5b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylcarbamazine targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:5991cede-6b31-11ec-b3df-0242ac110002 UniProtKB:E1G1C3 biolink:molecularly_interacts_with DrugCentral:873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylcarbamazine is positive modulator of Ion channel (Nematode GABA-A receptor) DrugCentral uuid:5991cede-6b31-11ec-b3df-0242ac110002 UniProtKB:E1G1C3 biolink:molecularly_interacts_with DrugCentral:873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylcarbamazine is positive modulator of Ion channel (Nematode GABA-A receptor) DrugCentral uuid:5991fde6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylpropion is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:5992229e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylpropion is inhibitor of Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:59924814-6b31-11ec-b3df-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.316']} DrugCentral uuid:59927456-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.894']} DrugCentral uuid:59929f12-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.252']} DrugCentral uuid:5992c7e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:5992f278-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.411']} DrugCentral uuid:59931c62-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.353']} DrugCentral uuid:59934570-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.296']} DrugCentral uuid:59936e60-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.276']} DrugCentral uuid:599397c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.178']} DrugCentral uuid:5993c0cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.439']} DrugCentral uuid:5993e9c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.864']} DrugCentral uuid:599412d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:59943e8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.575']} DrugCentral uuid:59946798-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.223']} DrugCentral uuid:5994907e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.272']} DrugCentral uuid:5994ba4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.525']} DrugCentral uuid:5994e344-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.437']} DrugCentral uuid:59950c3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.408']} DrugCentral uuid:599535ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.317']} DrugCentral uuid:59955f04-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.657']} DrugCentral uuid:599587f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5995b0da-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.778']} DrugCentral uuid:5995d9de-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.904']} DrugCentral uuid:599603a0-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:59962c86-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.274']} DrugCentral uuid:59965580-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.739']} DrugCentral uuid:59967e98-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:5996a864-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.019']} DrugCentral uuid:5996d15e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.593']} DrugCentral uuid:5996fa44-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:5997244c-6b31-11ec-b3df-0242ac110002 UniProtKB:P62508 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol is antagonist of Nuclear hormone receptor (Estrogen-related receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:59974dd2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:599776cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.983']} DrugCentral uuid:59979fc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.847']} DrugCentral uuid:5997c9f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.361']} DrugCentral uuid:5997f372-6b31-11ec-b3df-0242ac110002 UniProtKB:O95718 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol is antagonist of Nuclear hormone receptor (Steroid hormone receptor ERR2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:59981c44-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.483']} DrugCentral uuid:5998452a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:59986ece-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:599897aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.528']} DrugCentral uuid:5998c07c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.052']} DrugCentral uuid:5998e96c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.214']} DrugCentral uuid:599912d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:59993ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14376 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol targets Enzyme (UDP-glucose 4-epimerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:599964fa-6b31-11ec-b3df-0242ac110002 UniProtKB:O08580 biolink:molecularly_interacts_with DrugCentral:875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diethylstilbestrol is antagonist of Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:59998dd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 difenoxin is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:5999b6a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5999e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:599a0c34-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:599a35d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd1', 'has_quantitative_value': ['7.125']} DrugCentral uuid:599a5ee6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:599a87c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:599ab0bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflunisal is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:599ada06-6b31-11ec-b3df-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.648']} DrugCentral uuid:599b02d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.857']} DrugCentral uuid:599b2d6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:599b5210-6b31-11ec-b3df-0242ac110002 UniProtKB:P50997 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:599b7be6-6b31-11ec-b3df-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:599bbf48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:599bbf48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:599bbf48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:599bbf48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:599bbf48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:599bbf48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:599bbf48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:599bbf48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digitoxin targets Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:599c3c98-6b31-11ec-b3df-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.783']} DrugCentral uuid:599c6574-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.136']} DrugCentral uuid:599c8e64-6b31-11ec-b3df-0242ac110002 UniProtKB:P51449 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:599cb7b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P50997 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:599ce0a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:599d243c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:599d243c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:599d243c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:599d243c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:599d243c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:599d243c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:599d243c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:599d243c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13733 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin is inhibitor of Transporter (Sodium/potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:599da376-6b31-11ec-b3df-0242ac110002 UniProtKB:P51450 biolink:molecularly_interacts_with DrugCentral:882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 digoxin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:599dcc5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.007']} DrugCentral uuid:599df5f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:599e1ef0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.187']} DrugCentral uuid:599e47b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.526']} DrugCentral uuid:599e70c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:599e9a10-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:599ec300-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:599eebf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.085']} DrugCentral uuid:599f14e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.114']} DrugCentral uuid:599f428a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.121']} DrugCentral uuid:599f6ba2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:599f9492-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.699']} DrugCentral uuid:599fbe22-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.728']} DrugCentral uuid:599fe712-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.261']} DrugCentral uuid:59a00ff8-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.369']} DrugCentral uuid:59a038d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:59a0620a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:59a08b0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.299']} DrugCentral uuid:59a0b480-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:59a0dd48-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpha-Ergocryptine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:59a10908-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydrocodeine is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:59a12e56-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.087']} DrugCentral uuid:59a15746-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.462']} DrugCentral uuid:59a18018-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.23']} DrugCentral uuid:59a1aab6-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.309']} DrugCentral uuid:59a1d388-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.127']} DrugCentral uuid:59a1fc82-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:59a225d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.385']} DrugCentral uuid:59a24ee4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.373']} DrugCentral uuid:59a277ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.377']} DrugCentral uuid:59a2a0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.903']} DrugCentral uuid:59a2cafe-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:59a2f65a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:59a31ae0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.442']} DrugCentral uuid:59a343d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:59a36d60-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.605']} DrugCentral uuid:59a39646-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1D) DrugCentral uuid:59a3bad6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:59a3e3c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.183']} DrugCentral uuid:59a40cfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:59a4318c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:59a45a5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:59a48344-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.896']} DrugCentral uuid:59a4ae00-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:59a4d6e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.79']} DrugCentral uuid:59a4ffa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.14']} DrugCentral uuid:59a5288a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocristine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:59a5522e-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.804']} DrugCentral uuid:59a57b14-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.922']} DrugCentral uuid:59a5a3f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.529']} DrugCentral uuid:59a5ce70-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.412']} DrugCentral uuid:59a5f896-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:59a62190-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.424']} DrugCentral uuid:59a64a94-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.644']} DrugCentral uuid:59a67500-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.364']} DrugCentral uuid:59a69e72-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:59a6c762-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.83']} DrugCentral uuid:59a6f02a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:59a719ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:59a73e36-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.752']} DrugCentral uuid:59a7671c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.742']} DrugCentral uuid:59a78ff8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:59a7b974-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:59a7e250-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.821']} DrugCentral uuid:59a80b36-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.69']} DrugCentral uuid:59a83408-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:59a85aa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 5A) DrugCentral uuid:59a87f12-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:59a8a884-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:59a8d174-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.349']} DrugCentral uuid:59a8fb04-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.416']} DrugCentral uuid:59a923e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:59a94c9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.18']} DrugCentral uuid:59a97570-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:59a99ee2-6b31-11ec-b3df-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:59a9c7b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:59a9f194-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:59aa1bc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:59aa4522-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:59aa7592-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:59aa7592-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:59aa7592-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergotamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:59aab73c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:59aadbb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:59ab0034-6b31-11ec-b3df-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:59ab249c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:59ab4922-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:59ab6df8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:59ab927e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:59abc316-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:59abc316-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:59abc316-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:59ac0506-6b31-11ec-b3df-0242ac110002 UniProtKB:O54699 biolink:molecularly_interacts_with DrugCentral:893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilazep targets Transporter (Equilibrative nucleoside transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:59ac2dc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:59ac538a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:59ac7806-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:59ac9d36-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:59acc1bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dilevalol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:59aceaac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:59ad137e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.736']} DrugCentral uuid:59ad3ce6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:59ad6626-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:59ad8f2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:59adb8ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:59ade5c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.319']} DrugCentral uuid:59ae0ea0-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.017']} DrugCentral uuid:59ae37a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:59ae613e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:59ae8a10-6b31-11ec-b3df-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:59aeb2e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:59aedbaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:59af04f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:59af3578-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:59af3578-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:59af3578-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:59af7de4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:59af7de4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:59af7de4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:59afc3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P15388 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:59afeec8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:59b017a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JIS7 biolink:molecularly_interacts_with DrugCentral:897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diltiazem is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:59b04134-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:900 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimemorfan is inhibitor of Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:59b06a24-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.791']} DrugCentral uuid:59b0931e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.312']} DrugCentral uuid:59b0bc0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.695']} DrugCentral uuid:59b0e58a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.703']} DrugCentral uuid:59b10e7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:59b13850-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.479']} DrugCentral uuid:59b1614a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:59b18bca-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:59b1b4ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:59b1ddb4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.785']} DrugCentral uuid:59b20758-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:59b2302a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:59b25910-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.644']} DrugCentral uuid:59b2820a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.749']} DrugCentral uuid:59b2adb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.821']} DrugCentral uuid:59b2d692-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimenhydrinate targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.847']} DrugCentral uuid:59b2ff78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7KQK5 biolink:molecularly_interacts_with DrugCentral:902 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetacrine targets Unclassified (Apical membrane antigen 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:59b32840-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.16']} DrugCentral uuid:59b35446-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:59b37d2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:59b3a5fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:59b3ceee-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:59b3f87e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimetindene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:59b42916-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:59b42916-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:59b42916-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:59b46dd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:59b46dd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyltubocurarinium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:59b49d42-6b31-11ec-b3df-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:911 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dioxyline targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:59b4c600-6b31-11ec-b3df-0242ac110002 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:911 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dioxyline targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:59b4efea-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:59b51a10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:59b54472-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:59b56d58-6b31-11ec-b3df-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:59b59634-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:59b5bfa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:59b5e878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:59b61168-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:59b63a62-6b31-11ec-b3df-0242ac110002 UniProtKB:P37289 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:59b663ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:59b68c88-6b31-11ec-b3df-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:59b6b578-6b31-11ec-b3df-0242ac110002 UniProtKB:P43117 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:59b6de4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:59b70974-6b31-11ec-b3df-0242ac110002 UniProtKB:P43114 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:59b73264-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:59b75b68-6b31-11ec-b3df-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:59b784da-6b31-11ec-b3df-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:59b7adca-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.04']} DrugCentral uuid:59b7d6ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:59b8005e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.48']} DrugCentral uuid:59b82994-6b31-11ec-b3df-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:59b85270-6b31-11ec-b3df-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:59b87b6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:59b8a46e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:59b8cfac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:59b8fc20-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:59b924fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:59b94f0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:59b978a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:59b9a198-6b31-11ec-b3df-0242ac110002 UniProtKB:P32240 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:59b9ca6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:59b9f3be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:59ba1d3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43117 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:59ba462a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:59ba6ee8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43114 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:59ba9936-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:59bac55a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:59baf052-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:59bb1924-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is activator of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:59bb42b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:59bb6bc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.39']} DrugCentral uuid:59bb9462-6b31-11ec-b3df-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:913 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dinoprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:59bbbd66-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphemanil is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:59bbe278-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphemanil is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:59bc0708-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:59bc2fee-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.018']} DrugCentral uuid:59bc58de-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.432']} DrugCentral uuid:59bc852a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.148']} DrugCentral uuid:59bcae38-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:59bcd732-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.81']} DrugCentral uuid:59bd01d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:59bd2ade-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:59bd53b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:59bd7c82-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:59bda5b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:59bdcea8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.585']} DrugCentral uuid:59bdf78e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.932']} DrugCentral uuid:59be2074-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:59be4a90-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.678']} DrugCentral uuid:59be7b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:59be7b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:59be7b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:59bebbf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:59bee5a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenhydramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.658']} DrugCentral uuid:59bf0e9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:918 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenoxylate is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.167']} DrugCentral uuid:59bf3784-6b31-11ec-b3df-0242ac110002 UniProtKB:P22001 biolink:molecularly_interacts_with DrugCentral:918 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenoxylate targets Ion channel (Potassium voltage-gated channel subfamily A member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:59bf6056-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.076']} DrugCentral uuid:59bf89a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:59bfb286-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.377']} DrugCentral uuid:59bfdc7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline targets Enzyme (Cytochrome P450 2D6) DrugCentral uuid:59c00100-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diphenylpyraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:59c02c3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipivefrine is agonist of GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:59c050d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipivefrine is agonist of GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:59c075f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipivefrine is agonist of GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:59c09a66-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprafenone targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:59c0bf96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprafenone targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:59c0e50c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprafenone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:59c109a6-6b31-11ec-b3df-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:59c132aa-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:59c15bfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:59c18502-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:59c1ae06-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.802']} DrugCentral uuid:59c1d6f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:59c202a2-6b31-11ec-b3df-0242ac110002 UniProtKB:O95263 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:59c22b92-6b31-11ec-b3df-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:59c2548c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 7B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:59c27e08-6b31-11ec-b3df-0242ac110002 UniProtKB:O60658 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:59c2a6ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.158']} DrugCentral uuid:59c2cfe8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XSW7 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Cyclic nucleotide phosphodiesterase PDE3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:59c2f8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:O77823 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Cyclic AMP-specific phosphodiesterase SSPDE4A1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:59c3260a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:59c3260a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:59c35ee0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:59c35ee0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:59c3a6f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:59c3a6f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:59c3a6f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:59c3a6f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:59c3a6f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:59c3a6f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:59c4189e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:59c4189e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:59c4189e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:59c459d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:59c482ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86TP1 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Enzyme (Protein prune homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:59c4aba6-6b31-11ec-b3df-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:59c4d478-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DTD1 biolink:molecularly_interacts_with DrugCentral:924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dipyridamole is inhibitor of Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:59c4fdd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:59c5225c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.036']} DrugCentral uuid:59c54b2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.569']} DrugCentral uuid:59c573f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:59c59a84-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:59c5c2e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:59c5e7d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48544 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets Ion channel (G protein-activated inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:59c610c2-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:59c63a20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:926 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disopyramide targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.604']} DrugCentral uuid:59c6639c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 distigmine is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:59c68836-6b31-11ec-b3df-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.237']} DrugCentral uuid:59c6b130-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.846']} DrugCentral uuid:59c6da7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30536 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Transporter (Translocator protein) DrugCentral uuid:59c6ff00-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.967']} DrugCentral uuid:59c72836-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.115']} DrugCentral uuid:59c7514e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.735']} DrugCentral uuid:59c77d9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.156']} DrugCentral uuid:59c7a7ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.658']} DrugCentral uuid:59c7d0c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.129']} DrugCentral uuid:59c7fafe-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.833']} DrugCentral uuid:59c8240c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.434']} DrugCentral uuid:59c84cfc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.434']} DrugCentral uuid:59c875f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:59c89f54-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.957']} DrugCentral uuid:59c8c844-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.612']} DrugCentral uuid:59c8f148-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:59c91a2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.862']} DrugCentral uuid:59c9442c-6b31-11ec-b3df-0242ac110002 UniProtKB:P05091 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram is inhibitor of Enzyme (Aldehyde dehydrogenase, mitochondrial) DrugCentral uuid:59c968bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.319']} DrugCentral uuid:59c991ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.738']} DrugCentral uuid:59c9baa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25025 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (C-X-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.376']} DrugCentral uuid:59c9e3f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:59ca0cf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.821']} DrugCentral uuid:59ca35d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.794']} DrugCentral uuid:59ca5eca-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.669']} DrugCentral uuid:59ca8800-6b31-11ec-b3df-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.357']} DrugCentral uuid:59cab104-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.333']} DrugCentral uuid:59cad9e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P11884 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Aldehyde dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:59cb02c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99685 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Monoglyceride lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:59cb2e0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WMN3 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Bifunctional protein GlmU) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:59cb56f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28300 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Protein-lysine 6-oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:59cb7fda-6b31-11ec-b3df-0242ac110002 UniProtKB:P29375 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Lysine-specific demethylase 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:59cba924-6b31-11ec-b3df-0242ac110002 UniProtKB:P58215 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Lysyl oxidase homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:59cbd21e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96JB6 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Lysyl oxidase homolog 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:59cbfbcc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96KQ7 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Histone-lysine N-methyltransferase EHMT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:59cc25d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H9B1 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Histone-lysine N-methyltransferase EHMT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:59cc4f0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K0 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Enzyme (Lysyl oxidase homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:59cc7930-6b31-11ec-b3df-0242ac110002 UniProtKB:P57764 biolink:molecularly_interacts_with DrugCentral:928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disulfiram targets Unclassified (Gasdermin-D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:59cca22a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9VTU8 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 2, isoform A; LD26647p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:59cccb24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9V396 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 1; GH09688p) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:59ccf54a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:59cd1e62-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:59cd475c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:59cd7038-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:59cd99a0-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:59cdc2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P05181 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Cytochrome P450 2E1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:59cdebc6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:59ce14ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96KQ7 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Histone-lysine N-methyltransferase EHMT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:59ce3e3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H9B1 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Enzyme (Histone-lysine N-methyltransferase EHMT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:59ce6718-6b31-11ec-b3df-0242ac110002 UniProtKB:P57764 biolink:molecularly_interacts_with DrugCentral:931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ditiocarb targets Unclassified (Gasdermin-D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:59ce9008-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:59ceba88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R4D5 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:59cee3aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R455 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:59cf0c7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:59cf358a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7Z2W7 biolink:molecularly_interacts_with DrugCentral:934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenthol is activator of Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:59cf5ee8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:59cf87e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:59cfb0b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.976']} DrugCentral uuid:59cfd9b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.997']} DrugCentral uuid:59d0030c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:59d02cf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.868']} DrugCentral uuid:59d05668-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.771']} DrugCentral uuid:59d07f8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:59d0ac6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:59d0d886-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:59d10176-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:59d12ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:59d153ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:59d17cb4-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:59d1a5a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.256']} DrugCentral uuid:59d1cf02-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:59d1f7fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:59d220ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:59d249c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.258']} DrugCentral uuid:59d27588-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.401']} DrugCentral uuid:59d29eaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.301']} DrugCentral uuid:59d2c7ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:59d2f094-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:59d319e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:59d342d8-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:59d36cea-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.223']} DrugCentral uuid:59d39652-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:59d3bf38-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:59d3e846-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:59d41122-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:59d43cb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dobutamine targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:59d465aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:59d48e72-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:59d4b302-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:59d4d800-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.086']} DrugCentral uuid:59d500e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.283']} DrugCentral uuid:59d529e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02643 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets GPCR (Growth hormone-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:59d5718e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:59d5718e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:59d5718e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:59d5718e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:59d5718e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:59d5718e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:59d5718e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:59d5718e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:59d5718e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'ID50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:59d5fa0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC29 biolink:molecularly_interacts_with DrugCentral:939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docetaxel targets Cytosolic other (Nucleotide-binding oligomerization domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:59d64fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:59d64fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:59d64fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:59d64fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:59d64fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:59d64fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:59d64fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:59d64fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:59d64fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:59d64fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:59d64fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:59d64fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69091 biolink:molecularly_interacts_with DrugCentral:940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanol is inhibitor of Membrane other (Envelope glycoprotein) DrugCentral uuid:59d6e870-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dofetilide is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:59d7114c-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dofetilide targets Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:59d735e6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dofetilide is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:59d75f26-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.766']} DrugCentral uuid:59d7882a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:59d7b20a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.988']} DrugCentral uuid:59d7dc76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:59d805de-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:59d82ba4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:59d8549e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.586']} DrugCentral uuid:59d87e1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:59d8a714-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.781']} DrugCentral uuid:59d8d00e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.156']} DrugCentral uuid:59d8f8ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:59d92216-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.013']} DrugCentral uuid:59d94bce-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:59d974b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:59d99d90-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:59d9c8ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.833']} DrugCentral uuid:59d9f20e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.097']} DrugCentral uuid:59da1af4-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.936']} DrugCentral uuid:59da43b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.276']} DrugCentral uuid:59da6d38-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.553']} DrugCentral uuid:59da9d9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Cytosolic other (Calmodulin) DrugCentral uuid:59da9d9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Cytosolic other (Calmodulin) DrugCentral uuid:59da9d9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Cytosolic other (Calmodulin) DrugCentral uuid:59dad82c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:59db0176-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:59db2a5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:59db532e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:59db7c28-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.93']} DrugCentral uuid:59dba87e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:59dbd24a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:59dbfb58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domperidone targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:59dc25ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:59dc4f68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:59dc7844-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:59dca10c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.046']} DrugCentral uuid:59dccaec-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:59dcf3f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:59dd1cc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:59dd4594-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:59dd7096-6b31-11ec-b3df-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:59dd995e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:59ddc226-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:59ddeaf8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:59de146a-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:59de3d3c-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:59de660e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:59de8ef4-6b31-11ec-b3df-0242ac110002 UniProtKB:P32738 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Choline O-acetyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:59deb820-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:59dee304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:59df0bd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:59df35ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:59df5ec4-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 donepezil targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:59df87aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:59dfb090-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.19']} DrugCentral uuid:59dfda2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:59e00306-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:59e02bec-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.18']} DrugCentral uuid:59e054a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.084']} DrugCentral uuid:59e07dfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:59e0a6da-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:59e0cfb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:59e0f8a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:59e1227c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.375']} DrugCentral uuid:59e14b76-6b31-11ec-b3df-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:59e17466-6b31-11ec-b3df-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:59e19d88-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:59e1c6aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59e1ef72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:59e2184e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:59e2418e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:59e26a74-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:59e2936e-6b31-11ec-b3df-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:59e2bc5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:59e2e698-6b31-11ec-b3df-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:59e31050-6b31-11ec-b3df-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:59e33986-6b31-11ec-b3df-0242ac110002 UniProtKB:P09172 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Dopamine beta-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3']} DrugCentral uuid:59e36dde-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:59e36dde-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:59e36dde-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:59e36dde-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:59e3c298-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:59e3c298-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:59e3c298-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:59e40744-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:59e40744-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:59e44ba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:59e44ba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:59e44ba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:59e44ba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:59e44ba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:59e4ae1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:59e4ae1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:59e4ae1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:59e51058-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:59e51058-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:59e51058-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:59e51058-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:59e51058-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:59e51058-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:59e51058-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:59e51058-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:59e58eac-6b31-11ec-b3df-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:59e5b828-6b31-11ec-b3df-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:59e5e0f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8I2J3 biolink:molecularly_interacts_with DrugCentral:947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopamine targets Enzyme (M18 aspartyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:59e60a30-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopexamine targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:59e62eb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dopexamine targets GPCR (D(1A) dopamine receptor) DrugCentral uuid:59e65350-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:59e67c36-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:59e6a666-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:59e6cf60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:59e6f846-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:59e7219a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:59e74a8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:59e77398-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:59e79c7e-6b31-11ec-b3df-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:59e7c5b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:59e7eea4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:59e8179e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:59e8407a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:59e86a8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:59e89372-6b31-11ec-b3df-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:59e8bc62-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:59e8e55c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:59e90ea6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:59e937a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:59e96086-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:59e98a84-6b31-11ec-b3df-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:59e9b3ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:59e9dd68-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:59ea064e-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:59ea30ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:59ea59e6-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:59ea82cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:59eaace8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:59ead678-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:59eaff54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:59eb283a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:59eb512a-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dorzolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:59eb7a7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.066']} DrugCentral uuid:59eba364-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.337']} DrugCentral uuid:59ebcc4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.588']} DrugCentral uuid:59ebf526-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.378']} DrugCentral uuid:59ec2172-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:59ec4c7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:59ec755a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.744']} DrugCentral uuid:59ec9e9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:59ecc780-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:59ecf05c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:59ed1942-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.036']} DrugCentral uuid:59ed4282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dosulepin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.275']} DrugCentral uuid:59ed6b72-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxapram targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:59ed955c-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxapram is blocker of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:59edbb04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxapram is blocker of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:59ede0a2-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:59ee0974-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:59ee325a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:59ee5b68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:59ee84b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:59eeadac-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.845']} DrugCentral uuid:59eed69c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.631']} DrugCentral uuid:59eeffaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.545']} DrugCentral uuid:59ef2912-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:59ef520c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:59ef7af2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.827']} DrugCentral uuid:59efa3e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:59efd07e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:59eff9e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:59f022c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.381']} DrugCentral uuid:59f04bee-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.81']} DrugCentral uuid:59f074e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxazosin targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:59f09da6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:59f0c664-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:59f0ef90-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:59f1186c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:59f1415c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.17']} DrugCentral uuid:59f16b78-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.53']} DrugCentral uuid:59f19864-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:59f1c3de-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.45']} DrugCentral uuid:59f1ec9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:59f2156e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:59f23eb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:59f2679e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (5-hydroxytryptamine receptor 7) DrugCentral uuid:59f28c1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.629']} DrugCentral uuid:59f2b546-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:59f2de0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.325']} DrugCentral uuid:59f30708-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:59f32ff8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:59f35a46-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:59f38340-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:59f3ac30-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:59f3d502-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.086']} DrugCentral uuid:59f3fe4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:59f42732-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:59f45018-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:59f47908-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:59f4a23e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:59f4cb2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11']} DrugCentral uuid:59f4f400-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.886']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f55224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:59f61ee8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxepin is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:59f647e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:957 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxercalciferol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:59f66ccc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxifluridine targets Enzyme (Thymidylate synthase) DrugCentral uuid:59f69152-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.682']} DrugCentral uuid:59f6ba56-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:59f6e332-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.433']} DrugCentral uuid:59f70f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:59f7345e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:59f75db2-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:59f78242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:59f7a736-6b31-11ec-b3df-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:59f7cbd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.914']} DrugCentral uuid:59f7f4a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.496']} DrugCentral uuid:59f81d74-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.288']} DrugCentral uuid:59f846c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.605']} DrugCentral uuid:59f86fa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:59f898a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:59f8c27e-6b31-11ec-b3df-0242ac110002 UniProtKB:O14746 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Telomerase reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59f8edbc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:59f916ac-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:59f93f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61823 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Ribonuclease pancreatic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:59f9688c-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.867']} DrugCentral uuid:59f991ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.805']} DrugCentral uuid:59f9bad0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:59f9e3ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:59fa0d1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43870 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Unclassified (Type-2 restriction enzyme HindIII) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:59fa35fa-6b31-11ec-b3df-0242ac110002 UniProtKB:O52691 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Unclassified (Type-2 restriction enzyme ScaI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:59fa5ecc-6b31-11ec-b3df-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.84']} DrugCentral uuid:59fa8794-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WIQ1 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Enzyme (UDP-galactopyranose mutase) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:59fab232-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxorubicin targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:59fade1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:59fb02e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:59fb2ba4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08254 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Enzyme (Stromelysin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:59fb54ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P22894 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline is inhibitor of Enzyme (Neutrophil collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:59fb7dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P45452 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline is inhibitor of Enzyme (Collagenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:59fba6a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P02980 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Transporter (Tetracycline resistance protein, class B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:59fbcf78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:59fbf8ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P09237 biolink:molecularly_interacts_with DrugCentral:961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxycycline is inhibitor of Enzyme (Matrilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.14']} DrugCentral uuid:59fc21b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxylamine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:59fc4656-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:965 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drostanolone propionate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:59fc6af0-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.199']} DrugCentral uuid:59fc94e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.263']} DrugCentral uuid:59fd109a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.602']} DrugCentral uuid:59fd3fa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.954']} DrugCentral uuid:59fd68ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:59fd918c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:59fdbb9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.132']} DrugCentral uuid:59fde484-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.069']} DrugCentral uuid:59fe0ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.623']} DrugCentral uuid:59fe37ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.996']} DrugCentral uuid:59fe6288-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.027']} DrugCentral uuid:59fe8b64-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:59feb440-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:59fedd3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.782']} DrugCentral uuid:59ff06ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.592']} DrugCentral uuid:59ff2fa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.076']} DrugCentral uuid:59ff588c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.175']} DrugCentral uuid:59ff8190-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:59ffaada-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.695']} DrugCentral uuid:59ffd3ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.78']} DrugCentral uuid:59fffc7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5a002e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:5a002e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:5a002e06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:5a006ed4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drospirenone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.5']} DrugCentral uuid:5a0097ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drospirenone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5a00c0fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drospirenone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.5']} DrugCentral uuid:5a00e9c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:969 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drotaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:5a010f56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:969 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 drotaverine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:5a0133e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5a017c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:5a017c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:5a017c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:5a017c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:5a017c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:5a017c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:5a017c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:5a017c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:5a017c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is agonist of GPCR (Adrenergic receptor) DrugCentral uuid:5a01f36c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 droxidopa is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5a021d7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:5a02468c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5a026f72-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5a0298e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5a02c1b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:5a02eaa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5a03138c-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5a033d1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:5a0365f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.638']} DrugCentral uuid:5a038ed4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.402']} DrugCentral uuid:5a03b79c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:5a03e3f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5a040cce-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.352']} DrugCentral uuid:5a0435be-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.428']} DrugCentral uuid:5a045fbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.09']} DrugCentral uuid:5a04891a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5a04b2dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5a04dbc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duloxetine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5a05052a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dutasteride targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5a052e1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dutasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:5a055700-6b31-11ec-b3df-0242ac110002 UniProtKB:P18405 biolink:molecularly_interacts_with DrugCentral:973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dutasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:5a057fc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dyclonine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5a05a9ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dyclonine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:5a05cf96-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:975 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dydrogesterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5a05f890-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:975 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dydrogesterone targets Nuclear hormone receptor (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.561']} DrugCentral uuid:5a06218a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprophylline is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) DrugCentral uuid:5a06467e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diprophylline is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:5a066b0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:5a0693fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5a06bce4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.506']} DrugCentral uuid:5a06e642-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5a070f28-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5a0737fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.185']} DrugCentral uuid:5a0760f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:5a078c50-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:5a07b5cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.588']} DrugCentral uuid:5a07dec6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.701']} DrugCentral uuid:5a0807ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.905']} DrugCentral uuid:5a08311e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:5a085a18-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.472']} DrugCentral uuid:5a088308-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.384']} DrugCentral uuid:5a08abe4-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.543']} DrugCentral uuid:5a08d664-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5a08ff4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.554']} DrugCentral uuid:5a09283a-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.863']} DrugCentral uuid:5a095288-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.937']} DrugCentral uuid:5a097d76-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.615']} DrugCentral uuid:5a09a65c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.719']} DrugCentral uuid:5a09cf42-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.397']} DrugCentral uuid:5a09f936-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.106']} DrugCentral uuid:5a0a2226-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.743']} DrugCentral uuid:5a0a4b02-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:5a0a73f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5a0a9ecc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.126']} DrugCentral uuid:5a0ac794-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.253']} DrugCentral uuid:5a0af066-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.091']} DrugCentral uuid:5a0b194c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.976']} DrugCentral uuid:5a0b4354-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.191']} DrugCentral uuid:5a0b6c44-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.633']} DrugCentral uuid:5a0b952a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.849']} DrugCentral uuid:5a0bbe7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.871']} DrugCentral uuid:5a0be764-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:5a0c104a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.35']} DrugCentral uuid:5a0c3930-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5a0c62e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:979 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ebrotidine is antagonist of GPCR (Histamine H2 receptor) DrugCentral uuid:5a0c878c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 echothiophate is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:5a0cac12-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.131']} DrugCentral uuid:5a0cd50c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.543']} DrugCentral uuid:5a0d0086-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.636']} DrugCentral uuid:5a0d2caa-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.336']} DrugCentral uuid:5a0d5900-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5a0d81f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.086']} DrugCentral uuid:5a0dab44-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5a0dd434-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.052']} DrugCentral uuid:5a0dfd24-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:5a0e2614-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.648']} DrugCentral uuid:5a0e4fae-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.617']} DrugCentral uuid:5a0e788a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.034']} DrugCentral uuid:5a0ea184-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.939']} DrugCentral uuid:5a0ecb82-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.362']} DrugCentral uuid:5a0ef788-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.202']} DrugCentral uuid:5a0f229e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.296']} DrugCentral uuid:5a0f4b98-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.572']} DrugCentral uuid:5a0f74e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.792']} DrugCentral uuid:5a0f9dd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.805']} DrugCentral uuid:5a0fc73a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.197']} DrugCentral uuid:5a0ff02a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.936']} DrugCentral uuid:5a1019b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.421']} DrugCentral uuid:5a1042aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.529']} DrugCentral uuid:5a106b7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.336']} DrugCentral uuid:5a109476-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.178']} DrugCentral uuid:5a10be24-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:5a10e6f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.006']} DrugCentral uuid:5a1110cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:5a113a84-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.485']} DrugCentral uuid:5a11637e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.359']} DrugCentral uuid:5a118db8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.463']} DrugCentral uuid:5a11b6b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:5a11dc00-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.294']} DrugCentral uuid:5a1204e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5a122dc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.864']} DrugCentral uuid:5a125694-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5a128132-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:5a12aa68-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.489']} DrugCentral uuid:5a12d33a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.189']} DrugCentral uuid:5a12fc16-6b31-11ec-b3df-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5a13256a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:5a134e46-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.916']} DrugCentral uuid:5a13772c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.857']} DrugCentral uuid:5a13a080-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:5a13ca10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5a13f2ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.155']} DrugCentral uuid:5a141bbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5a144490-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.697']} DrugCentral uuid:5a146e48-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.171']} DrugCentral uuid:5a14972e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.999']} DrugCentral uuid:5a14c028-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.431']} DrugCentral uuid:5a14e968-6b31-11ec-b3df-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.503']} DrugCentral uuid:5a151244-6b31-11ec-b3df-0242ac110002 UniProtKB:P49146 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Neuropeptide Y receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.959']} DrugCentral uuid:5a153c24-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.498']} DrugCentral uuid:5a156528-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.875']} DrugCentral uuid:5a158ea4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:5a15b7f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:5a15e0e8-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:5a1609ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:5a163458-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5a165d34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5a16861a-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:5a16af00-6b31-11ec-b3df-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5a16d836-6b31-11ec-b3df-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:5a170126-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96D31 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Ion channel (Calcium release-activated calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5a172a16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 econazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.51']} DrugCentral uuid:5a175374-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edatrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.36']} DrugCentral uuid:5a177c3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edatrexate targets Enzyme (Folylpolyglutamate synthase, mitochondrial) DrugCentral uuid:5a17a0d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edatrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5a17c9b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edatrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5a17f3a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5a181cc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16739 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Ceramide glucosyltransferase) DrugCentral uuid:5a18428e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q79MP6 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5a186b88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XAY4 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Unclassified (Beta-lactamase VIM-1; Class B carbapenemase VIM-1; Metallo-beta-lactamase; Metallo-beta-lactamase VIM-1; Metallobeta-lactamase; VIM-1; VIM-1 metallo-beta lactamase; VIM-1 metallo-beta-lactamase; VIM-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:5a1894c8-6b31-11ec-b3df-0242ac110002 UniProtKB:J3SE37 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:5a18bda4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5a18e68a-6b31-11ec-b3df-0242ac110002 UniProtKB:O00167 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Eyes absent homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5a190f7a-6b31-11ec-b3df-0242ac110002 UniProtKB:O00167 biolink:molecularly_interacts_with DrugCentral:987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edetic acid targets Enzyme (Eyes absent homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5a193a18-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edrophonium is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.79']} DrugCentral uuid:5a1962f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edrophonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5a198c02-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:5a19b4ca-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:5a19daea-6b31-11ec-b3df-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz is inhibitor of Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5a1a03f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5a1a2cde-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5a1a55d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:5a1a7fa4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efavirenz targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:5a1aa894-6b31-11ec-b3df-0242ac110002 UniProtKB:P11926 biolink:molecularly_interacts_with DrugCentral:990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eflornithine is inhibitor of Enzyme (Ornithine decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5a1ad17a-6b31-11ec-b3df-0242ac110002 UniProtKB:P09057 biolink:molecularly_interacts_with DrugCentral:990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eflornithine targets Enzyme (Ornithine decarboxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:5a1afa92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9TZZ6 biolink:molecularly_interacts_with DrugCentral:990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eflornithine is inhibitor of Enzyme (Ornithine decarboxylase) DrugCentral uuid:5a1b1fd6-6b31-11ec-b3df-0242ac110002 UniProtKB:O54898 biolink:molecularly_interacts_with DrugCentral:992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efonidipine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5a1b48c6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efonidipine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.621']} DrugCentral uuid:5a1b7594-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efonidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:5a1b7594-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efonidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:5a1ba546-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5a1bce4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5a1bf744-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5a1c202a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5a1c497e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eletriptan is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5a1c7278-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elliptinium targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5a1c9b54-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elliptinium targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5a1cc41c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elliptinium targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5a1cf504-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:5a1cf504-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:5a1cf504-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1d7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltanolone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5a1e5552-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emedastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:5a1e7e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:5a1ea78c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:5a1ed068-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.578']} DrugCentral uuid:5a1ef944-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:5a1f2220-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5a1f4c5a-6b31-11ec-b3df-0242ac110002 UniProtKB:O75884 biolink:molecularly_interacts_with DrugCentral:1001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emetine targets Enzyme (Putative hydrolase RBBP9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5a1f75cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1003 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emtricitabine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:5a1f9b38-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1005 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5a1fc414-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1005 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5a1fed9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:1005 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5a20168a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5a203f52-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5a206856-6b31-11ec-b3df-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:5a2091a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5EGZ1 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5a20ba86-6b31-11ec-b3df-0242ac110002 UniProtKB:P09470 biolink:molecularly_interacts_with DrugCentral:1006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enalaprilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.94']} DrugCentral uuid:5a20e33a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5a2107ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:5a212d9a-6b31-11ec-b3df-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:5a2151f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:5a2176f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:1007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encainide targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:5a219b68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 endralazine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:5a21c084-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is positive modulator of Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:5a21e50a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:5a22099a-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:5a222e20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:5a225332-6b31-11ec-b3df-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:5a2277b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:1009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:5a229c20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q53I07 biolink:molecularly_interacts_with DrugCentral:1010 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfuvirtide targets Viral envelope protein (Envelope glycoprotein) DrugCentral uuid:5a22c0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:O40239 biolink:molecularly_interacts_with DrugCentral:1010 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfuvirtide is inhibitor of Membrane other (Transmembrane glycoprotein gp41) DrugCentral uuid:5a22e590-6b31-11ec-b3df-0242ac110002 UniProtKB:Q76270 biolink:molecularly_interacts_with DrugCentral:1010 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfuvirtide targets Unclassified (GP41) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5a231182-6b31-11ec-b3df-0242ac110002 UniProtKB:P43700 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin targets Enzyme (DNA gyrase subunit A) DrugCentral uuid:5a233612-6b31-11ec-b3df-0242ac110002 UniProtKB:P21281 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin targets Enzyme (V-type proton ATPase subunit B, brain isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5a2362c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5EP76 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:5a2362c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5EP76 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:5a239620-6b31-11ec-b3df-0242ac110002 UniProtKB:P48371 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5a239620-6b31-11ec-b3df-0242ac110002 UniProtKB:P48371 biolink:molecularly_interacts_with DrugCentral:1013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5a23c65e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.345']} DrugCentral uuid:5a23fb92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5a23fb92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5a23fb92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5a23fb92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoximone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5a2448b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5a247180-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:5a249a7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5a24c464-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.03']} DrugCentral uuid:5a24ed9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:5a251234-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5a253b10-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5a2564b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5a258d9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5a25b676-6b31-11ec-b3df-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:1015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprofylline targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.04']} DrugCentral uuid:5a25df48-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5a260860-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5a263114-6b31-11ec-b3df-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil targets GPCR (Prostacyclin receptor) DrugCentral uuid:5a26559a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5a267e8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5a26a842-6b31-11ec-b3df-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.13']} DrugCentral uuid:5a26d128-6b31-11ec-b3df-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:1016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enprostil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5a26fa04-6b31-11ec-b3df-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5a2722d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:5a274c0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9C0B1 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone targets Unclassified (Alpha-ketoglutarate-dependent dioxygenase FTO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5a2774f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9C0B1 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone targets Unclassified (Alpha-ketoglutarate-dependent dioxygenase FTO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5a279e5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:1018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entacapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.523']} DrugCentral uuid:5a27c830-6b31-11ec-b3df-0242ac110002 UniProtKB:P17394 biolink:molecularly_interacts_with DrugCentral:1019 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entecavir targets Polyprotein (Protein P) DrugCentral uuid:5a27ed42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:1019 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entecavir is inhibitor of Polyprotein (Protein P) DrugCentral uuid:5a2811aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:1019 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entecavir targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:5a283a68-6b31-11ec-b3df-0242ac110002 UniProtKB:P14550 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5a28633a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5a288cca-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5a28b59c-6b31-11ec-b3df-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5a28de64-6b31-11ec-b3df-0242ac110002 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5a290772-6b31-11ec-b3df-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5a29303a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00796 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat targets Enzyme (Sorbitol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:5a295916-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02928 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat is inhibitor of Enzyme (Cytochrome P450 4A11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5a2981e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epalrestat is inhibitor of Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.678']} DrugCentral uuid:5a29ab5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eperisone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:5a29d436-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eperisone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.859']} DrugCentral uuid:5a29fd26-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eperisone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:5a2a271a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eperisone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5a2a51f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1024 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ephedrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5a2a7ce2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:5a2aa17c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5a2aca1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5a2af1c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:5a2b162a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5a2b3ab0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:5a2b636e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (Histamine H2 receptor) DrugCentral uuid:5a2b884e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5a2bb102-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5a2bd9de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5a2c03aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinastine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5a2c2d44-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.401']} DrugCentral uuid:5a2c5648-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5a2c7f1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.26']} DrugCentral uuid:5a2ca80a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:5a2cd190-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.559']} DrugCentral uuid:5a2cfa76-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.434']} DrugCentral uuid:5a2d238e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5a2d4cd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.401']} DrugCentral uuid:5a2d779e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.449']} DrugCentral uuid:5a2da0b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5a2dc9a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5a2df3ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.484']} DrugCentral uuid:5a2e1cf8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5a2e45e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5a2e6eba-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5a2e980e-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5a2ec0d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5a2ee9c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5a2f12c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10608 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:5a2f3c0a-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5a2f6c84-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5a2f6c84-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5a2f6c84-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5a2fb4fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5a2fb4fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5a2fb4fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5a2ff91a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8I2J3 biolink:molecularly_interacts_with DrugCentral:1028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epinephrine targets Enzyme (M18 aspartyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5a3021e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1030 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epirubicin targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.878']} DrugCentral uuid:5a304adc-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1030 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epirubicin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.286']} DrugCentral uuid:5a30758e-6b31-11ec-b3df-0242ac110002 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:1030 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epirubicin targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5a309e6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:5a30c746-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5a30f036-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5a3119e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Transcription factor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5a3142ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5a316bba-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear other (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5a319630-6b31-11ec-b3df-0242ac110002 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:1032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eplerenone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5a31c218-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoprostenol is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5a31eb3a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:1034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoprostenol targets GPCR (P2Y purinoceptor 12) DrugCentral uuid:5a320fca-6b31-11ec-b3df-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:1034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoprostenol is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5a3239d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoprostenol is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5a3262cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5a328ba8-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5a32b47a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5a32e18e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5a32e18e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5a331e06-6b31-11ec-b3df-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5a331e06-6b31-11ec-b3df-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5a331e06-6b31-11ec-b3df-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eprosartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5a336460-6b31-11ec-b3df-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:1040 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eptifibatide is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:5a336460-6b31-11ec-b3df-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:1040 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eptifibatide is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:5a339d5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:5a33c66c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5a33ef2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:5a341888-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.333']} DrugCentral uuid:5a34415a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5a346a40-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.58']} DrugCentral uuid:5a349326-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:5a34bc7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:5a34e54c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.879']} DrugCentral uuid:5a350e46-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.714']} DrugCentral uuid:5a353718-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5a3561f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.367']} DrugCentral uuid:5a358aba-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5a35b38c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.889']} DrugCentral uuid:5a35dcb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:5a36058a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5a362e70-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.578']} DrugCentral uuid:5a365760-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.621']} DrugCentral uuid:5a36808c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.722']} DrugCentral uuid:5a36a972-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:5a36d258-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:5a36fc74-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.099']} DrugCentral uuid:5a37269a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5a375048-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.354']} DrugCentral uuid:5a377924-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5a37a23c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:5a37cb86-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5a37f462-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5a381d3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5a3841e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.754']} DrugCentral uuid:5a386b2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.836']} DrugCentral uuid:5a3893fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5a38bd98-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.064']} DrugCentral uuid:5a38e804-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:5a3912ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:5a393bce-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5a3964aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.742']} DrugCentral uuid:5a398dea-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.487']} DrugCentral uuid:5a39b6da-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5a39dfde-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5a3a0950-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5a3a3326-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:5a3a5be4-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:5a3a84b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.514']} DrugCentral uuid:5a3aad7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.342']} DrugCentral uuid:5a3ad786-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.041']} DrugCentral uuid:5a3b0058-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:5a3b290c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.11']} DrugCentral uuid:5a3b51c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5a3b7c0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5a3ba4e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5a3bcdda-6b31-11ec-b3df-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5a3bf71a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5a3c200a-6b31-11ec-b3df-0242ac110002 UniProtKB:O08786 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets GPCR (Cholecystokinin A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:5a3c48d2-6b31-11ec-b3df-0242ac110002 UniProtKB:O32393 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine targets Unclassified (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:5a3c71ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P35364 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5a3c9b8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5a3cc47e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergotamine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5a3ced46-6b31-11ec-b3df-0242ac110002 UniProtKB:O00206 biolink:molecularly_interacts_with DrugCentral:1044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eritoran targets Membrane receptor (Toll-like receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5a3d162c-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5a3d3f62-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5a3d6834-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:5a3d9106-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5a3dbb2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5a3de462-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5a3e0d3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5a3e361a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5a3e5f1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5a3e8af2-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5a3eb3ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5a3edcc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:5a3f0612-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5a3f2ee4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5a3f57ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5a3f81a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5a3faae0-6b31-11ec-b3df-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5a3fd3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5a3ffc84-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5a40254c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5a404f86-6b31-11ec-b3df-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5a407876-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5a40a1f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5a40cace-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5a40f422-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5a411d08-6b31-11ec-b3df-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5a4145d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5a416f24-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5a419864-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5a41c136-6b31-11ec-b3df-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.03']} DrugCentral uuid:5a41ea1c-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5a421492-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5a423d78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5a42664a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5a428f12-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5a42b85c-6b31-11ec-b3df-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5a42e14c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5a430a28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5a43330e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5a435c58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5a438624-6b31-11ec-b3df-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5a43aef6-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5a43d7d2-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5a440202-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5a442aca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:5a44539c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5a447c64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5a44a6d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5a44cf98-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.51']} DrugCentral uuid:5a44f874-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5a4521b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5a454aa4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5a45738a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:5a459c5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5a45c754-6b31-11ec-b3df-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5a45f076-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5a46195c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:5a464224-6b31-11ec-b3df-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5a466b5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3U3Q1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5a469436-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5a46bd08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5a46e5e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5a470f2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5a473814-6b31-11ec-b3df-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5a4760dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5a478c24-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5a47b5d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5a47deae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:5a480780-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:5a4830d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5a4859b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5a488282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5a48ab54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5a48d49e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6DT37 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase MRCK gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5a48fd7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5a492642-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5a494f1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5a497a84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5a49a392-6b31-11ec-b3df-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5a49cc64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5a49f554-6b31-11ec-b3df-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5a4a1ef8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31152 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5a4a47ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5a4a709c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5a4a99e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5a4ac2c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5a4aeb94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5a4b1466-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5a4b3dec-6b31-11ec-b3df-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5a4b67ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:5a4b91ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5a4bba88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5a4be422-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5a4c0cfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:5a4c35da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5a4c5eb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5a4c880a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5a4cb0e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5a4cd9cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5a4d02a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5a4d2cec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5a4d55d2-6b31-11ec-b3df-0242ac110002 UniProtKB:O94956 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib is inhibitor of Transporter (Solute carrier organic anion transporter family member 2B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5a4d7ecc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28028 biolink:molecularly_interacts_with DrugCentral:1045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erlotinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5a4da820-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X6V3 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (Penicillin-binding protein 2) DrugCentral uuid:5a4dcc9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (Penicillin-binding protein 4) DrugCentral uuid:5a4df122-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X6V7 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (D-ala-D-ala-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase family protein; Penicillin-binding protein 5) DrugCentral uuid:5a4e163e-6b31-11ec-b3df-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:5a4e3aba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7CHG0 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem targets Enzyme (D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6) DrugCentral uuid:5a4e5fc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem is inhibitor of Enzyme (D-alanyl-D-alanine carboxypeptidase DacB) DrugCentral uuid:5a4e8448-6b31-11ec-b3df-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem is inhibitor of Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5a4ea8d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:1046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertapenem is inhibitor of Enzyme (Penicillin-binding protein 1B) DrugCentral uuid:5a4ecd54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:5a4ef888-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.824']} DrugCentral uuid:5a4f2150-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5a4f4a18-6b31-11ec-b3df-0242ac110002 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:5a4f7312-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5a4f9d7e-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5a4fc646-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erythromycin propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:5a4fef18-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:5a501858-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.186']} DrugCentral uuid:5a504134-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.597']} DrugCentral uuid:5a506a06-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.412']} DrugCentral uuid:5a5092ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.706']} DrugCentral uuid:5a50bccc-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.906']} DrugCentral uuid:5a50e5b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5a510e8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5a513756-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 escitalopram targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5a51610e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esmolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5a5189d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esmolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5a51b2a8-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esmolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:5a51df76-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esomeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:5a51df76-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esomeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:5a5217d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5a5217d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5a5217d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5a5258e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5a5258e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5a5258e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5a529bc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5a529bc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5a529bc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5a52dcf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5a52dcf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5a52dcf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5a53176a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.243']} DrugCentral uuid:5a5340fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.538']} DrugCentral uuid:5a5369cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.725']} DrugCentral uuid:5a53929e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.926']} DrugCentral uuid:5a53bb98-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:5a53e4d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5a540db4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol is activator of Ion channel (Calcium-activated potassium channel subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5a543690-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5a5460c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5a5489f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5a54b35e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Enzyme (Steryl-sulfatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:5a54dc26-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.83']} DrugCentral uuid:5a550584-6b31-11ec-b3df-0242ac110002 UniProtKB:P11474 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.44']} DrugCentral uuid:5a552e4c-6b31-11ec-b3df-0242ac110002 UniProtKB:O95718 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Nuclear hormone receptor (Steroid hormone receptor ERR2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:5a55571e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5a557ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.947']} DrugCentral uuid:5a55a8fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.372']} DrugCentral uuid:5a55d1ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:5a55fac0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:5a562388-6b31-11ec-b3df-0242ac110002 UniProtKB:O08537 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:5a564f5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19785 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:5a5678e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5a56a5a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:5a56a5a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:5a56dbe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:5a5704c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.767']} DrugCentral uuid:5a572dc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.133']} DrugCentral uuid:5a57569a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.637']} DrugCentral uuid:5a577fd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.446']} DrugCentral uuid:5a57a8ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:5a57d2d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:5a57fbcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.94']} DrugCentral uuid:5a582566-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.638']} DrugCentral uuid:5a584e38-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.156']} DrugCentral uuid:5a58771e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1058 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol benzoate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.902']} DrugCentral uuid:5a58a018-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol cypionate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:5a58c552-6b31-11ec-b3df-0242ac110002 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:1062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol mustard targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5a58ee2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol valerate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:5a5912c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estramustine phosphate is modulator of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:5a59373a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:1066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estramustine phosphate targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5a596066-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06124 biolink:molecularly_interacts_with DrugCentral:1066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estramustine phosphate targets Enzyme (Tyrosine-protein phosphatase non-receptor type 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5a598924-6b31-11ec-b3df-0242ac110002 UniProtKB:P29350 biolink:molecularly_interacts_with DrugCentral:1066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estramustine phosphate targets Enzyme (Protein-tyrosine phosphatase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:5a59b20a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5a59db86-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:5a5a05b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:5a5a2f14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.9']} DrugCentral uuid:5a5a57f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5a5a8176-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.63']} DrugCentral uuid:5a5aaa5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5a5ad40a-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:5a5afcfa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:1067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol succinate targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5a5b261c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5a5b4f2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:5a5b781a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:5a5ba10a-6b31-11ec-b3df-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:5a5bd508-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5a5bd508-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5a5bd508-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5a5c1680-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) DrugCentral uuid:5a5c1680-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) DrugCentral uuid:5a5c1680-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) DrugCentral uuid:5a5c583e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) DrugCentral uuid:5a5c583e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) DrugCentral uuid:5a5c583e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) DrugCentral uuid:5a5c992a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) DrugCentral uuid:5a5c992a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) DrugCentral uuid:5a5c992a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) DrugCentral uuid:5a5cda34-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) DrugCentral uuid:5a5cda34-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) DrugCentral uuid:5a5cda34-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) DrugCentral uuid:5a5d1bc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) DrugCentral uuid:5a5d1bc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) DrugCentral uuid:5a5d1bc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eszopiclone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) DrugCentral uuid:5a5d563a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid is inhibitor of Transporter (Solute carrier family 12 member 1) DrugCentral uuid:5a5d7ac0-6b31-11ec-b3df-0242ac110002 UniProtKB:P09211 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Enzyme (Glutathione S-transferase P) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5a5da6f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08263 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Enzyme (Glutathione S-transferase A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5a5dd402-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.939']} DrugCentral uuid:5a5dfe14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14376 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Enzyme (UDP-glucose 4-epimerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5a5e279a-6b31-11ec-b3df-0242ac110002 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:1071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacrynic acid targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5a5e5062-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5a5e7920-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5a5ea1de-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5a5ecb0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5a5ef3c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WNL8 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Probable arabinosyltransferase A) DrugCentral uuid:5a5f1844-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WNL6 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Probable arabinosyltransferase B) DrugCentral uuid:5a5f3cc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WNL5 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Probable arabinosyltransferase C) DrugCentral uuid:5a5f6240-6b31-11ec-b3df-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:5a5f8b12-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WNL9 biolink:molecularly_interacts_with DrugCentral:1073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethambutol is inhibitor of Enzyme (Probable arabinosyltransferase A) DrugCentral uuid:5a5faf84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:5a5fd40a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:5a5ff99e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (Glycine receptor subunit alpha-2) DrugCentral uuid:5a6025cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (GABA A receptor alpha-4/beta-2/delta) DrugCentral uuid:5a6025cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (GABA A receptor alpha-4/beta-2/delta) DrugCentral uuid:5a6025cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1076 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethanol targets Ion channel (GABA A receptor alpha-4/beta-2/delta) DrugCentral uuid:5a606776-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethchlorvynol is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5a606776-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethchlorvynol is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5a606776-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethchlorvynol is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5a60a13c-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.877']} DrugCentral uuid:5a60ca36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5a60f312-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.964']} DrugCentral uuid:5a611bf8-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:5a614754-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:5a617332-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.022']} DrugCentral uuid:5a619c54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.244']} DrugCentral uuid:5a61c620-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:5a61efc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.353']} DrugCentral uuid:5a6218a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:5a624190-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.985']} DrugCentral uuid:5a626ae4-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.83']} DrugCentral uuid:5a6293c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5a62bc88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:5a62e564-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.81']} DrugCentral uuid:5a630fbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5a6338d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.246']} DrugCentral uuid:5a63619c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.857']} DrugCentral uuid:5a638bae-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5a63b52a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5a63ddfc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethinylestradiol targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:5a6406ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WIE4 biolink:molecularly_interacts_with DrugCentral:1083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethionamide targets Enzyme (Catalase-peroxidase) DrugCentral uuid:5a642b68-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:1083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethionamide is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) DrugCentral uuid:5a645052-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethionamide targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5a64791a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.022']} DrugCentral uuid:5a64a200-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.78']} DrugCentral uuid:5a64cadc-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:5a64f5d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.111']} DrugCentral uuid:5a651eb0-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1084 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethisterone targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:5a65478c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5a656c08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:5a659142-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5a65ba14-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5a65e3ea-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:5a660d48-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:5a6636b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:5a665f78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5a668868-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1086 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 profenamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:5a66b202-6b31-11ec-b3df-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1087 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethosuximide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:5a66f898-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5a66f898-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5a66f898-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5a66f898-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5a66f898-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5a66f898-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5a66f898-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5a66f898-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5a66f898-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5a66f898-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethotoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5a677aca-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:5a67a3ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5a67ccbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:5a67f612-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:5a681f20-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5a684824-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5a68711e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5a689d1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:5a68c664-6b31-11ec-b3df-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:5a68ef5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5a69186c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5a6941de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5a696c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5a699594-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5a69bee8-6b31-11ec-b3df-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5a69e7f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5a6a10fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5a6a39e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:5a6a63f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:5a6a8cec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5a6ab5d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5a6aded6-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5a6b0816-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:5a6b3110-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:5a6b5a96-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5a6b8390-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:5a6bacd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5a6bd5b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:5a6c028e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5a6c028e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide is inhibitor of Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5a6c39ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3SZX4 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5a6c65bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:5a6c8ec0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:5a6cb7ba-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethoxzolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.03']} DrugCentral uuid:5a6ce0fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:1091 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl biscoumacetate targets Enzyme (Vitamin K epoxide reductase complex subunit 1) DrugCentral uuid:5a6d05b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:5a6d2ec0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.682']} DrugCentral uuid:5a6d57ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.983']} DrugCentral uuid:5a6d8230-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:5a6dab48-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:5a6dcfe2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:5a6df8dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.889']} DrugCentral uuid:5a6e24e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:5a6e4de6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethylestrenol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:5a6e76c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:5a6e9bb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:5a6ec442-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.368']} DrugCentral uuid:5a6eed14-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:5a6f160e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etynodiol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:5a6f3fd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5a6f647e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:5a6f8918-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:5a6fadee-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:5a6fd846-6b31-11ec-b3df-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5a700352-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidocaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:5a702c2e-6b31-11ec-b3df-0242ac110002 UniProtKB:B1LRJ1 biolink:molecularly_interacts_with DrugCentral:1098 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etidronic acid targets Unclassified (Type IV secretion-like conjugative transfer relaxase protein TraI) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5a705546-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1100 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etilamfetamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5a707ea4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1101 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etilefrine is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:5a70ab68-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5a70ab68-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5a70ab68-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5a70f3de-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5a70f3de-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5a70f3de-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5a71354c-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5a71354c-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5a71354c-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5a717796-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5a717796-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5a717796-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etizolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5a71b2c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etodolac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5a71ddd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1103 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etodolac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.577']} DrugCentral uuid:5a7206c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:1107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etofylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:5a722fce-6b31-11ec-b3df-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5a725904-6b31-11ec-b3df-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5a7281fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:5a72aada-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5a72db68-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:5a72db68-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:5a72db68-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:5a732474-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5a732474-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5a732474-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etomidate targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5a736510-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etonogestrel targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:5a738acc-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etonogestrel is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:5a73af48-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etonogestrel targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.23']} DrugCentral uuid:5a73d838-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.638']} DrugCentral uuid:5a74010a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.051']} DrugCentral uuid:5a742a54-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.071']} DrugCentral uuid:5a745344-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:5a747c0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.282']} DrugCentral uuid:5a74a5d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.21']} DrugCentral uuid:5a74cf18-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:5a74f3b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide is inhibitor of Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5a751c84-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:5a7540ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:5a7567ca-6b31-11ec-b3df-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:5a758e30-6b31-11ec-b3df-0242ac110002 UniProtKB:O15438 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Transporter (Canalicular multispecific organic anion transporter 2) DrugCentral uuid:5a75b2ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:5a75db92-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.497']} DrugCentral uuid:5a7604e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5a762dcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5a76569e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.102']} DrugCentral uuid:5a767f98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5a76a8ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5a76d1d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoricoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5a76fb3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5a77242a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5a775134-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5a777bc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5a77a49a-6b31-11ec-b3df-0242ac110002 UniProtKB:O15438 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Transporter (Canalicular multispecific organic anion transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5a77cdd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5a77f6b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:5a781b50-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5a78440e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5a786d4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:1115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etravirine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5a789742-6b31-11ec-b3df-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:1116 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etretinate is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) DrugCentral uuid:5a78bcc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:1116 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etretinate is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) DrugCentral uuid:5a78e134-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etryptamine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.63']} DrugCentral uuid:5a790af6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etryptamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:5a7933b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etryptamine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5a795c7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 everolimus targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5a798116-6b31-11ec-b3df-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:1118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 everolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5a79aa4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:1118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 everolimus is inhibitor of Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5a79d31e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exemestane targets Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:5a79f7c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exemestane is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.692']} DrugCentral uuid:5a7a208a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:1123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exenatide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.18']} DrugCentral uuid:5a7a4a2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32301 biolink:molecularly_interacts_with DrugCentral:1123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exenatide targets GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:5a7a7314-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHC9 biolink:molecularly_interacts_with DrugCentral:1125 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ezetimibe is antagonist of Membrane other (Niemann-Pick C1-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5a7a9c0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6T3U3 biolink:molecularly_interacts_with DrugCentral:1125 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ezetimibe targets Unclassified (Niemann-Pick C1-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5a7ac526-6b31-11ec-b3df-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fadrozole is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5a7af168-6b31-11ec-b3df-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fadrozole is inhibitor of Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5a7b1a6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15539 biolink:molecularly_interacts_with DrugCentral:1126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fadrozole targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5a7b4366-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fadrozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:5a7b6c88-6b31-11ec-b3df-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:1128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:5a7b9104-6b31-11ec-b3df-0242ac110002 UniProtKB:P09252 biolink:molecularly_interacts_with DrugCentral:1128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famciclovir targets Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:5a7bb59e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.93']} DrugCentral uuid:5a7bde8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:5a7c077e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:5a7c3262-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5a7c5b66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5a7c84f6-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:5a7caf44-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.84']} DrugCentral uuid:5a7cda82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5a7d0372-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5a7d2c80-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:5a7d55d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5a7d7ec4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:5a7da7be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5a7dd0a4-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5a7dfa2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5a7e231a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5a7e4be2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.304']} DrugCentral uuid:5a7e74be-6b31-11ec-b3df-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famotidine targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:5a7e9f02-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:1130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 famprofazone targets Nuclear hormone receptor (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.18']} DrugCentral uuid:5a7ec7de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5a7ef0b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5a7f19fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5a7f42ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5a7f6bda-6b31-11ec-b3df-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5a7f94a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P13500 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Cytokine (C-C motif chemokine 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5a7fbe14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:5a7fe704-6b31-11ec-b3df-0242ac110002 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:5a800fd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62868 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5a8038c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil is inhibitor of Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5a8063dc-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:1132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fasudil is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.11']} DrugCentral uuid:5a808db2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 febuxostat targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:5a80b68e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:1137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 febuxostat is inhibitor of Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5a80e05a-6b31-11ec-b3df-0242ac110002 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:1137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 febuxostat targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5a8109a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22985 biolink:molecularly_interacts_with DrugCentral:1137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 febuxostat targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5a813294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felbamate is antagonist of Ion channel (Glutamate receptor ionotropic, NMDA 2A) DrugCentral uuid:5a815724-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felbamate is antagonist of Ion channel (Glutamate receptor ionotropic, NMDA 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.284']} DrugCentral uuid:5a81800a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felbinac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:5a81a56c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felbinac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.049']} DrugCentral uuid:5a81ce3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:5a81f79c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:5a8220aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:5a824648-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:5a826ae2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.339']} DrugCentral uuid:5a8293be-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.168']} DrugCentral uuid:5a82bc9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5a82e5e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine is activator of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5a8317a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:5a8317a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:5a8317a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felodipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:5a835858-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbufen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5a8381de-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbufen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5a83aaba-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbufen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:5a83cf54-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbufen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:5a83f3e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5a841ed2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline targets GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5a8447b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:5a8470a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5a849a06-6b31-11ec-b3df-0242ac110002 UniProtKB:P35384 biolink:molecularly_interacts_with DrugCentral:1148 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendiline is positive allosteric modulator of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:5a84c3b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.004']} DrugCentral uuid:5a84ec9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.111']} DrugCentral uuid:5a85158a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.428']} DrugCentral uuid:5a853f06-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.176']} DrugCentral uuid:5a8567f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.172']} DrugCentral uuid:5a8590e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.845']} DrugCentral uuid:5a85b9cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.398']} DrugCentral uuid:5a85e546-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5a860eb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.042']} DrugCentral uuid:5a863794-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.378']} DrugCentral uuid:5a866160-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5a868abe-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.717']} DrugCentral uuid:5a86b39a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.016']} DrugCentral uuid:5a86dc6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.726']} DrugCentral uuid:5a8705d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.489']} DrugCentral uuid:5a872ed8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.167']} DrugCentral uuid:5a8757be-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:5a8780ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.195']} DrugCentral uuid:5a87aaf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.735']} DrugCentral uuid:5a87d748-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.848']} DrugCentral uuid:5a880146-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenfluramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:5a882a2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.673']} DrugCentral uuid:5a88538a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:5a887c7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.906']} DrugCentral uuid:5a88a556-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.331']} DrugCentral uuid:5a88cfc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.032']} DrugCentral uuid:5a88f984-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.164']} DrugCentral uuid:5a892274-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.492']} DrugCentral uuid:5a894b3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.808']} DrugCentral uuid:5a89742c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5a899f10-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5a89c7ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5a89f0e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenofibrate targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:5a8a1a4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5a8a4334-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:5a8a6c10-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5a8a950a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5a8abe86-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5a8ae76c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5a8b1052-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5a8b394c-6b31-11ec-b3df-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5a8b6d22-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5a8b6d22-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5a8b6d22-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5a8bae40-6b31-11ec-b3df-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:5a8bd744-6b31-11ec-b3df-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:1153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoldopam targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:5a8c007a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:5a8c297e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:5a8c5250-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:5a8c7f1e-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:5a8c7f1e-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:5a8cb5c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N695 biolink:molecularly_interacts_with DrugCentral:1154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoprofen is inhibitor of Transporter (Sodium-coupled monocarboxylate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5a8cdeaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5a8d0790-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5a8d326a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.001']} DrugCentral uuid:5a8d5e66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.45']} DrugCentral uuid:5a8d8918-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5a8db1fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:5a8ddba2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5a8e0488-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:5a8e2d6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5a8e565e-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:5a8e7f9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:5a8ea884-6b31-11ec-b3df-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:5a8ed1f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5a8efc26-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:5a8f2642-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5a8f4f28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5a8f8380-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:5a8f8380-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:5a8f8380-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:5a8f8380-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:5a8fd498-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5a8fd498-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5a900b02-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:5a903456-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Unclassified (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5a905e18-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentanyl targets Unclassified (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.45']} DrugCentral uuid:5a9086ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:1165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fentiazac targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5a90afda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fexofenadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:5a90d9ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fexofenadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5a9102f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fexofenadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5a912bc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P46721 biolink:molecularly_interacts_with DrugCentral:1170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fexofenadine targets Transporter (Solute carrier organic anion transporter family member 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5a9154b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5a917e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5a91a714-6b31-11ec-b3df-0242ac110002 UniProtKB:P14060 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5a91cffa-6b31-11ec-b3df-0242ac110002 UniProtKB:P24008 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:5a91f8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.55']} DrugCentral uuid:5a9225f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:5a9225f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:5a925b14-6b31-11ec-b3df-0242ac110002 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5a92840e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18405 biolink:molecularly_interacts_with DrugCentral:1171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 finasteride is inhibitor of Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:5a92ad9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.704']} DrugCentral uuid:5a92e228-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:5a92e228-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:5a92e228-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:5a92e228-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 4) DrugCentral uuid:5a9329cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 7) DrugCentral uuid:5a9329cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 7) DrugCentral uuid:5a935d84-6b31-11ec-b3df-0242ac110002 UniProtKB:O95263 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 8) DrugCentral uuid:5a935d84-6b31-11ec-b3df-0242ac110002 UniProtKB:O95263 biolink:molecularly_interacts_with DrugCentral:1175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flavoxate is inhibitor of Enzyme (Phosphodiesterase 8) DrugCentral uuid:5a938c8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5a93b572-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5a93dec6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide targets Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.745']} DrugCentral uuid:5a9408a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:5a94318c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.77']} DrugCentral uuid:5a945a68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5a948560-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63881 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide targets Ion channel (Potassium voltage-gated channel subfamily D member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5a94b13e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15388 biolink:molecularly_interacts_with DrugCentral:1176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flecainide is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5a94daec-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:1177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fleroxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:5a9503d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floctafenine is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.959']} DrugCentral uuid:5a952d6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floctafenine is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.268']} DrugCentral uuid:5a95565c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:1180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flopropione is inhibitor of Enzyme (Catechol O-methyltransferase) DrugCentral uuid:5a957ad8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5a959f4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxacillin targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5a95c894-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:1183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxacillin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5a95f2ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxuridine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:5a961768-6b31-11ec-b3df-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:1184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 floxuridine targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5a964030-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5a966ba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5a96947c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5a96bd58-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5a96e6e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5a970fe2-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5a9738d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5a9761ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5a978b02-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5a97b3f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7Z1V1 biolink:molecularly_interacts_with DrugCentral:1187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluconazole targets Enzyme (Sterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5a97dcba-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flucytosine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5a980690-6b31-11ec-b3df-0242ac110002 UniProtKB:P0CS13 biolink:molecularly_interacts_with DrugCentral:1188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flucytosine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:5a982c56-6b31-11ec-b3df-0242ac110002 UniProtKB:P12461 biolink:molecularly_interacts_with DrugCentral:1188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flucytosine is inhibitor of Enzyme (Thymidylate synthase) DrugCentral uuid:5a9850e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P02829 biolink:molecularly_interacts_with DrugCentral:1188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flucytosine targets Cytosolic other (ATP-dependent molecular chaperone HSP82) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5a9879d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5a98a2bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5a98cc4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:5a98f546-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:5a991e40-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5a994726-6b31-11ec-b3df-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5a99708e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:5a999988-6b31-11ec-b3df-0242ac110002 UniProtKB:P09884 biolink:molecularly_interacts_with DrugCentral:1189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludarabine phosphate is inhibitor of Enzyme (DNA polymerase alpha catalytic subunit) DrugCentral uuid:5a99be0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludrocortisone acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5a99e6d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:1191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludrocortisone acetate targets Cytosolic other (Annexin A1) DrugCentral uuid:5a9a0c2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludrocortisone acetate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:5a9a3514-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.93']} DrugCentral uuid:5a9a5e86-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5a9a8762-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:5a9ab0e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:5a9ad9ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5a9b02b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5a9b2bfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5a9b54da-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5a9b7dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5a9ba66a-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5a9bd0a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6UVM3 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is activator of Ion channel (Potassium channel subfamily T member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5a9bfcdc-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5a9c25b8-6b31-11ec-b3df-0242ac110002 UniProtKB:O94759 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily M member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:5a9c4e94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TD43 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5a9c7824-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5a9ca0ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5a9ccad6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZQ8 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily M member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:5a9cf3da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7TN37 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily M member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5a9d1db0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:5a9d46a0-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5a9d6fa4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:5a9d986c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:5a9dc24c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYV8 biolink:molecularly_interacts_with DrugCentral:1193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flufenamic acid is agonist of GPCR (Taste receptor type 2 member 14) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.863']} DrugCentral uuid:5a9deb28-6b31-11ec-b3df-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1194 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5a9e140e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5a9e3dc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:5a9e66c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:5a9e8f88-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5a9eb88c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5a9ee992-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:5a9ee992-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:5a9ee992-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:5a9f3226-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.979']} DrugCentral uuid:5a9f3226-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.979']} DrugCentral uuid:5a9f3226-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.979']} DrugCentral uuid:5a9f7df8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:5a9f7df8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:5a9f7df8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:5a9fc790-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:5a9fc790-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:5a9fc790-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa04242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aa13184-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:5aa13184-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:5aa13184-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:5aa13184-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:5aa13184-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:5aa13184-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:5aa1a0ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5aa1a0ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5aa1a0ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5aa1e9e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5aa1e9e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5aa1e9e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5aa23246-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5aa23246-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5aa23246-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5aa27ac6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:5aa27ac6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:5aa27ac6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil is allosteric antagonist of Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa2f438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1195 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumazenil targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5aa3d2cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1198 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flumetasone pivalate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5aa3f748-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.621']} DrugCentral uuid:5aa4202e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5aa44900-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.713']} DrugCentral uuid:5aa47254-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.932']} DrugCentral uuid:5aa49b3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.662']} DrugCentral uuid:5aa4c40c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5aa4ecf2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.304']} DrugCentral uuid:5aa517a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:5aa54076-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.877']} DrugCentral uuid:5aa56a7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.612']} DrugCentral uuid:5aa593e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.936']} DrugCentral uuid:5aa5bccc-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:5aa5e5c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.455']} DrugCentral uuid:5aa60ea2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:5aa63800-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:5aa661c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:5aa68a9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.151']} DrugCentral uuid:5aa6b38e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.504']} DrugCentral uuid:5aa6defe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.103']} DrugCentral uuid:5aa707e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5aa730ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:5aa759a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5aa783b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.333']} DrugCentral uuid:5aa7aca8-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.532']} DrugCentral uuid:5aa7d58e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.357']} DrugCentral uuid:5aa7fed8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5aa827be-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5aa85090-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.78']} DrugCentral uuid:5aa8796c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:5aa8a2f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5aa8cbce-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5aa8f48c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5aa91d54-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5aa946a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:5aa9772c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:5aa9772c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:5aa9772c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:5aa9b818-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y256 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:5aa9e14e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5aaa0a0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8HY88 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5aaa33ec-6b31-11ec-b3df-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5aaa5cd2-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5aaa87ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunarizine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:5aaab0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunisolide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5aaad982-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunisolide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:5aab0272-6b31-11ec-b3df-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:5aab2c34-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:5aab5556-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5aab7e5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5aabaf56-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5aabaf56-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5aabaf56-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5aabf948-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5aabf948-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5aabf948-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5aac42a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:5aac42a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:5aac42a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:5aac8bb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:5aac8bb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:5aac8bb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:5aacd444-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:5aacd444-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:5aacd444-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:5aad1e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:5aad1e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:5aad1e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aad98d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5aae7e20-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:5aae7e20-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:5aae7e20-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:5aaec6fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5aaec6fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5aaec6fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5aaf109c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5aaf109c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5aaf109c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5aaf599e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5aaf599e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5aaf599e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5aafa372-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5aafa372-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5aafa372-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flunitrazepam targets Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5aafe454-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1204 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluocinolone acetonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.848']} DrugCentral uuid:5ab00e0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1204 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluocinolone acetonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.475']} DrugCentral uuid:5ab036de-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1205 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluocinonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.622']} DrugCentral uuid:5ab05fba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1205 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluocinonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.538']} DrugCentral uuid:5ab08940-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorescein targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.042']} DrugCentral uuid:5ab0b21c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:1207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorescein targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:5ab0dae4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:1207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorescein targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:5ab103ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:1207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorescein targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:5ab12d00-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorometholone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.801']} DrugCentral uuid:5ab155d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorometholone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.067']} DrugCentral uuid:5ab17e9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorometholone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:5ab1a762-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.356']} DrugCentral uuid:5ab1d0fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5ab1f9d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5ab2239a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:5ab24c80-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.091']} DrugCentral uuid:5ab27610-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5ab29eec-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:5ab2c7dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5ab2f09a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5ab319ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:5ab342c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5ab36bb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.156']} DrugCentral uuid:5ab39536-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5ab3be12-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.959']} DrugCentral uuid:5ab3e6da-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.047']} DrugCentral uuid:5ab40fb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.569']} DrugCentral uuid:5ab438e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5ab461be-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.538']} DrugCentral uuid:5ab48a9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.569']} DrugCentral uuid:5ab4b376-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.444']} DrugCentral uuid:5ab4dcac-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:5ab5056a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5ab52ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5ab557a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5ab581ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5ab5aa7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:5ab5d35a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5ab5fd76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.84']} DrugCentral uuid:5ab627a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.97']} DrugCentral uuid:5ab6508c-6b31-11ec-b3df-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5ab67972-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5ab6a2c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5ab6cb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5ab6ffe6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5ab6ffe6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5ab6ffe6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5ab6ffe6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5ab755e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5ab755e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5ab755e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5ab79e38-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5ab79e38-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5ab79e38-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5ab7df6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5ab80846-6b31-11ec-b3df-0242ac110002 UniProtKB:P25122 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine targets Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:5ab8310e-6b31-11ec-b3df-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxetine is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5ab859d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoxymesterone is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:5ab8832a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5ab8ac10-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5ab8d4ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.65']} DrugCentral uuid:5ab8fd8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.095']} DrugCentral uuid:5ab92906-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.058']} DrugCentral uuid:5ab95214-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5ab977b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:5ab9a084-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5ab9c9ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.066']} DrugCentral uuid:5ab9f278-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:5aba1b54-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5aba4408-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:5aba6d34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:5aba9610-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5abacdec-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5abacdec-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5abacdec-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5abacdec-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5abacdec-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupentixol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5abb27a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.075']} DrugCentral uuid:5abb506e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.649']} DrugCentral uuid:5abb794a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.269']} DrugCentral uuid:5abba38e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.503']} DrugCentral uuid:5abbcd96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.067']} DrugCentral uuid:5abbf672-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5abc1fa8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.101']} DrugCentral uuid:5abc4898-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.711']} DrugCentral uuid:5abc714c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.838']} DrugCentral uuid:5abc9a00-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.044']} DrugCentral uuid:5abcc46c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:5abced5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:5abd16f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.464']} DrugCentral uuid:5abd3fc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:5abd6908-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.191']} DrugCentral uuid:5abd91da-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.087']} DrugCentral uuid:5abdbaa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:5abde37e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.887']} DrugCentral uuid:5abe0c8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.793']} DrugCentral uuid:5abe355e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:5abe5e1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5abe8702-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.575']} DrugCentral uuid:5abeb1a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.999']} DrugCentral uuid:5abeda72-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.315']} DrugCentral uuid:5abf0330-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.447']} DrugCentral uuid:5abf2c3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.655']} DrugCentral uuid:5abf5538-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:5abf7dec-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:5abfa6c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.539']} DrugCentral uuid:5abfcffe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.788']} DrugCentral uuid:5abff8c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.171']} DrugCentral uuid:5ac02198-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.535']} DrugCentral uuid:5ac04a56-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.019']} DrugCentral uuid:5ac074ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:5ac09d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.005']} DrugCentral uuid:5ac0c670-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.072']} DrugCentral uuid:5ac0ef2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:5ac1197c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:5ac14244-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.397']} DrugCentral uuid:5ac16b0c-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5ac193b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.097']} DrugCentral uuid:5ac1bce2-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.708']} DrugCentral uuid:5ac1e5be-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.125']} DrugCentral uuid:5ac20e86-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5ac2374e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.67']} DrugCentral uuid:5ac26372-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:5ac28d84-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.061']} DrugCentral uuid:5ac2b66a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.049']} DrugCentral uuid:5ac2df82-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.013']} DrugCentral uuid:5ac30854-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:5ac330fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.78']} DrugCentral uuid:5ac359d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5ac38356-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5ac3ac32-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5ac3dcac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5ac3dcac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5ac3dcac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5ac4388c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5ac4388c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5ac4388c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5ac4388c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5ac4388c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5ac4388c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5ac4388c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5ac4388c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1212 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5ac4b668-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine decanoate is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:5ac4dae4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:5ac503c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.268']} DrugCentral uuid:5ac52c88-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.503']} DrugCentral uuid:5ac55618-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.225']} DrugCentral uuid:5ac57f08-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.837']} DrugCentral uuid:5ac5a7ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.979']} DrugCentral uuid:5ac5d0b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.048']} DrugCentral uuid:5ac5faa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5ac62368-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:5ac64c44-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:5ac6750c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.087']} DrugCentral uuid:5ac69e42-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.611']} DrugCentral uuid:5ac6c70a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.887']} DrugCentral uuid:5ac6efdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:5ac718a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:5ac7422a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.961']} DrugCentral uuid:5ac76afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.145']} DrugCentral uuid:5ac793c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.841']} DrugCentral uuid:5ac7bdb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.274']} DrugCentral uuid:5ac7e978-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.447']} DrugCentral uuid:5ac81240-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:5ac83c02-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.476']} DrugCentral uuid:5ac86524-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.539']} DrugCentral uuid:5ac88f4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:5ac8b808-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:5ac8e0f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:5ac90a60-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluphenazine enanthate targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:5ac9335a-6b31-11ec-b3df-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:1215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupirtine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5ac95c04-6b31-11ec-b3df-0242ac110002 UniProtKB:O43525 biolink:molecularly_interacts_with DrugCentral:1215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupirtine targets Ion channel (Potassium voltage-gated channel subfamily KQT member 3) DrugCentral uuid:5ac98094-6b31-11ec-b3df-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:1215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flupirtine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5ac9ac5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1216 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluprednisolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5ac9d42c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludroxycortide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.695']} DrugCentral uuid:5ac9fd30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fludroxycortide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:5aca25f8-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurazepam targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.222']} DrugCentral uuid:5aca56f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5aca56f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5aca56f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5aca97ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.39']} DrugCentral uuid:5acac076-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5acaea7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5acb136e-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:5acb3c40-6b31-11ec-b3df-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5acb6648-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:5acb9186-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5acbba58-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5acbe316-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flurbiprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5acc0d28-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.229']} DrugCentral uuid:5acc35e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.292']} DrugCentral uuid:5acc5ecc-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.436']} DrugCentral uuid:5acc878a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.244']} DrugCentral uuid:5accb0d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5accd9a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5acd0296-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5acd2b54-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5acd5714-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:5acd7fe6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:5acda8b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.409']} DrugCentral uuid:5acdd176-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5acdfafc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.951']} DrugCentral uuid:5ace23d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5ace4d04-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.208']} DrugCentral uuid:5ace7644-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.056']} DrugCentral uuid:5ace9f20-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5acec7e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5acef0ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:1222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluspirilene targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5acf1cde-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:5acf4628-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.082']} DrugCentral uuid:5acf6f2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5acf97f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.356']} DrugCentral uuid:5acfc198-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.049']} DrugCentral uuid:5acfea56-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutamide targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5ad0142c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.74']} DrugCentral uuid:5ad03cfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:5ad066c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.77']} DrugCentral uuid:5ad08f7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47712 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate targets Enzyme (Cytosolic phospholipase A2) DrugCentral uuid:5ad0b404-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:1225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone propionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.12']} DrugCentral uuid:5ad0dcc2-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutrimazole targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5ad107ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flutrimazole targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:5ad13064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:5ad154ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:5ad17e70-6b31-11ec-b3df-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5ad1a760-6b31-11ec-b3df-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5ad1d03c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5ad1f92c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5ad2226c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:1229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5ad24b3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:5ad2742e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:5ad29d1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.951']} DrugCentral uuid:5ad2c73a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:5ad2eff8-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5ad318f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:5ad341e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1230 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluvoxamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:5ad36b36-6b31-11ec-b3df-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 folic acid targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5ad3941c-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:1231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 folic acid targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:5ad3bce4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leucovorin targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.071']} DrugCentral uuid:5ad3e5de-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:1232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leucovorin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:5ad41810-6b31-11ec-b3df-0242ac110002 UniProtKB:P07327 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole is inhibitor of Enzyme (Alcohol dehydrogenase) DrugCentral uuid:5ad41810-6b31-11ec-b3df-0242ac110002 UniProtKB:P07327 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole is inhibitor of Enzyme (Alcohol dehydrogenase) DrugCentral uuid:5ad41810-6b31-11ec-b3df-0242ac110002 UniProtKB:P07327 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole is inhibitor of Enzyme (Alcohol dehydrogenase) DrugCentral uuid:5ad4553c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5ad4553c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00328 biolink:molecularly_interacts_with DrugCentral:1233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fomepizole targets Enzyme (Alcohol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5ad48b1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P01008 biolink:molecularly_interacts_with DrugCentral:1236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fondaparinux is activator of Secreted (Antithrombin-III) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:5ad4b3d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1238 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formestane targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:5ad4dcc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5ad505c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5ad52ee4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5ad557b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5ad580a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5ad5aa9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5ad5d416-6b31-11ec-b3df-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:1239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 formoterol targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:5ad5fd60-6b31-11ec-b3df-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosamprenavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:5ad62204-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosamprenavir is inhibitor of Enzyme (Pol polyprotein) DrugCentral uuid:5ad64694-6b31-11ec-b3df-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:1241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 foscarnet is inhibitor of Enzyme (DNA polymerase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:5ad670ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P08546 biolink:molecularly_interacts_with DrugCentral:1241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 foscarnet targets Enzyme (DNA polymerase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5ad6998c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 foscarnet targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:5ad6c254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:1241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 foscarnet targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5ad6eb08-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfluconazole targets Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:5ad70ffc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q836E5 biolink:molecularly_interacts_with DrugCentral:1243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfomycin targets Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1) DrugCentral uuid:5ad73464-6b31-11ec-b3df-0242ac110002 UniProtKB:Q831A8 biolink:molecularly_interacts_with DrugCentral:1243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfomycin targets Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2) DrugCentral uuid:5ad7591c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A749 biolink:molecularly_interacts_with DrugCentral:1243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfomycin is inhibitor of Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5ad781da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HVW7 biolink:molecularly_interacts_with DrugCentral:1243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfomycin targets Enzyme (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5ad7ab6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosinopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5ad7d41e-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosinopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5ad7fdfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosphenytoin is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5ad82284-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 frovatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5ad84e4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 frovatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.99']} DrugCentral uuid:5ad878a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 frovatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:5ad8a1aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fructose targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5ad8ca54-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ftivazide targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:5ad8f3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:5ad91c8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:5ad94560-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant is antagonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:5ad96ef0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.68']} DrugCentral uuid:5ad997d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant is antagonist of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5ad9c0bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5ad9e97a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5ada13d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11474 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5ada3e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:5ada66de-6b31-11ec-b3df-0242ac110002 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:5ada8fba-6b31-11ec-b3df-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:1255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fulvestrant targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:5adab8dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furaltadone targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:5adae1c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5adb0a8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:5adb2f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5adb5904-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5adb81ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5adbaabc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5adbd3ac-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:5adbfe40-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5adc2726-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5adc5124-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5adc7a82-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:5adca354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:5adccc4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5adcf516-6b31-11ec-b3df-0242ac110002 UniProtKB:P55011 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide is inhibitor of Transporter (Solute carrier family 12 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5add1e7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5add476e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5add7040-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5add9926-6b31-11ec-b3df-0242ac110002 UniProtKB:P96618 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Enzyme (Holo-[acyl-carrieir-protein] synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5addc414-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furosemide targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5added36-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fusidic acid targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:5ade1608-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fusidic acid targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:5ade3ec6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5ade67e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23978 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5ade90a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31648 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5adeb96e-6b31-11ec-b3df-0242ac110002 UniProtKB:P62813 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5adee20e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23576 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5adf0ba8-6b31-11ec-b3df-0242ac110002 UniProtKB:P24046 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit rho-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5adf3470-6b31-11ec-b3df-0242ac110002 UniProtKB:P48066 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5adf5d60-6b31-11ec-b3df-0242ac110002 UniProtKB:P48065 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent betaine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5adf86f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31650 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5adfb0da-6b31-11ec-b3df-0242ac110002 UniProtKB:P31646 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5adfda7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31649 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:5ae00350-6b31-11ec-b3df-0242ac110002 UniProtKB:P23574 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Ion channel (Gamma-aminobutyric acid receptor subunit gamma-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5ae02c72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z0U4 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid is agonist of GPCR (Gamma-aminobutyric acid type B receptor subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5ae0554e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSD5 biolink:molecularly_interacts_with DrugCentral:1262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobutyric acid targets Transporter (Sodium- and chloride-dependent GABA transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:5ae07e0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5ae0a27e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:5ae0c790-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets GPCR (Adenosine receptor A1) DrugCentral uuid:5ae0ec0c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75899 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets GPCR (Gamma-aminobutyric acid type B receptor subunit 2) DrugCentral uuid:5ae11088-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:5ae134fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.523']} DrugCentral uuid:5ae15f66-6b31-11ec-b3df-0242ac110002 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:5ae18b3a-6b31-11ec-b3df-0242ac110002 UniProtKB:O43525 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:5ae1b4fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:5ae1ddba-6b31-11ec-b3df-0242ac110002 UniProtKB:O08532 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5ae20722-6b31-11ec-b3df-0242ac110002 UniProtKB:O77773 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin targets Ion channel (Uncharacterized protein; Voltage-dependent calcium channel alpha-2 delta subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5ae22ffe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY47 biolink:molecularly_interacts_with DrugCentral:1264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.928']} DrugCentral uuid:5ae258da-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5ae281c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5ae2ab50-6b31-11ec-b3df-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5ae2d418-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5ae2fce0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:5ae326de-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:5ae351e0-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5ae37abc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5ae3a38e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5ae3cdd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galantamine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:5ae3f6b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5ae41f8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:5ae4485c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5ae471d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5ae49aaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5ae4c37c-6b31-11ec-b3df-0242ac110002 UniProtKB:P02708 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine is blocker of Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5ae4ec62-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallamine is negative allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.148']} DrugCentral uuid:5ae51e4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallopamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5ae51e4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallopamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5ae51e4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallopamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5ae55f12-6b31-11ec-b3df-0242ac110002 UniProtKB:P31213 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Enzyme (3-oxo-5-alpha-steroid 4-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5ae587ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5ae5b124-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5ae5d9f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5ae602be-6b31-11ec-b3df-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5ae62b9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:1276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gamolenic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:5ae65516-6b31-11ec-b3df-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:5ae67974-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets Kinase (Thymidine kinase) DrugCentral uuid:5ae69dfa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13255 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets GPCR (Metabotropic glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5ae6c6d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41594 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5ae6f160-6b31-11ec-b3df-0242ac110002 UniProtKB:P10210 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets Enzyme (Capsid scaffolding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5ae71a32-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WP01 biolink:molecularly_interacts_with DrugCentral:1277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganciclovir targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5ae743a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ganirelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) DrugCentral uuid:5ae76816-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5ae79246-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:5ae7bf00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:5ae7bf00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:5ae7f1fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5ae7f1fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5ae82562-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5ae82562-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gatifloxacin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5ae85a32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5ae8830e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5ae8ac12-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5ae8d69c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5ae8ff82-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5ae9287c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5ae952de-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5ae97c32-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5ae9a50e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5ae9cdea-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5ae9f75c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5aea202e-6b31-11ec-b3df-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5aea48f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:5aea71dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5aea9d4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5aeac664-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5aeaef36-6b31-11ec-b3df-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5aeb1808-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5aeb4148-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5aeb6b28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5aeb93fa-6b31-11ec-b3df-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5aebbd58-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:5aebe620-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5aec0efc-6b31-11ec-b3df-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5aec37ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5aec6168-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:5aec8a30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5aecb30c-6b31-11ec-b3df-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5aecdbd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5aed0564-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5aed2e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5aed571c-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5aed7fee-6b31-11ec-b3df-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5aedaa14-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5aedd2e6-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5aedfbc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5aee2548-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5aee51ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:5aee7c3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5aeea522-6b31-11ec-b3df-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5aeecec6-6b31-11ec-b3df-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5aeef7c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3U3Q1 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5aef2128-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5aef49fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5aef7434-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5aef9d1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5aefc614-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5aefeee6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5af01a6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5af04544-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5af06e20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:5af096fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5af0c08c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5af0e972-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5af11244-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5af13b98-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5af1647e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5af18d78-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5af1b65e-6b31-11ec-b3df-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5af1e0a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5af20974-6b31-11ec-b3df-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5af2325a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16659 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5af25b36-6b31-11ec-b3df-0242ac110002 UniProtKB:P31152 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5af284a8-6b31-11ec-b3df-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5af2ad7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:5af2d638-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5af2ff96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:5af328d6-6b31-11ec-b3df-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5af351b2-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5af37b88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:5af3a45a-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.16']} DrugCentral uuid:5af3cdea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5af3f6c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5af41fa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5af44932-6b31-11ec-b3df-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5af4720e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:5af49ae0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5af4c3b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5af4ecde-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5af515b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gefitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5af53e82-6b31-11ec-b3df-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine targets Enzyme (Thymidylate synthase) DrugCentral uuid:5af562fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:5af588ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) DrugCentral uuid:5af5ad54-6b31-11ec-b3df-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) DrugCentral uuid:5af5d1d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30085 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine targets Kinase (UMP-CMP kinase) DrugCentral uuid:5af5fdfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:5af5fdfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:5af5fdfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07864 biolink:molecularly_interacts_with DrugCentral:1283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemcitabine is inhibitor of Enzyme (DNA polymerase (alpha/delta/epsilon)) DrugCentral uuid:5af63814-6b31-11ec-b3df-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Enzyme (Lipoprotein lipase) DrugCentral uuid:5af65c86-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:5af68558-6b31-11ec-b3df-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5af6af56-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.523']} DrugCentral uuid:5af6d8e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:5af701ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:5af72a9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemfibrozil targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5af753fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemifloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5af77e18-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES7 biolink:molecularly_interacts_with DrugCentral:1286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemifloxacin targets Enzyme (DNA gyrase subunit B) DrugCentral uuid:5af7a2a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P72525 biolink:molecularly_interacts_with DrugCentral:1286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemifloxacin is inhibitor of Enzyme (DNA topoisomerase 4 subunit A) DrugCentral uuid:5af7c71a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gestodene targets Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:5af7eb78-6b31-11ec-b3df-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gestodene targets Enzyme (Cytochrome P450 3A5) DrugCentral uuid:5af810b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1292 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gestrinone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:5af83998-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12882 biolink:molecularly_interacts_with DrugCentral:1293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gimeracil is inhibitor of Enzyme (Dihydropyrimidine dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.638']} DrugCentral uuid:5af8624c-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glafenine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:5af88b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glafenine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5af8b896-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5af8b896-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5af8f176-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.046']} DrugCentral uuid:5af8f176-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibornuride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.046']} DrugCentral uuid:5af92b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5af92b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5af968a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.222']} DrugCentral uuid:5af968a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliclazide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.222']} DrugCentral uuid:5af9a170-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:5af9a170-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:5af9daf0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:5af9daf0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glimepiride is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:5afa13bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1301 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glipizide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.097']} DrugCentral uuid:5afa13bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1301 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glipizide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.097']} DrugCentral uuid:5afa4c88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliquidone is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5afa4c88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gliquidone is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5afa85cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glisoxepide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.959']} DrugCentral uuid:5afa85cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glisoxepide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.959']} DrugCentral uuid:5afabba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5afae486-6b31-11ec-b3df-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:5afb0f56-6b31-11ec-b3df-0242ac110002 UniProtKB:P42261 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:5afb3850-6b31-11ec-b3df-0242ac110002 UniProtKB:P39086 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5afb6140-6b31-11ec-b3df-0242ac110002 UniProtKB:P42262 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5afb8a26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13255 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5afbb35c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00367 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutamate dehydrogenase 1, mitochondrial) DrugCentral uuid:5afbd7d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P49448 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutamate dehydrogenase 2, mitochondrial) DrugCentral uuid:5afbfc5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5afc2530-6b31-11ec-b3df-0242ac110002 UniProtKB:P41594 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5afc4e70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14833 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5afc7742-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5afca168-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13002 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5afcca58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13003 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5afcf4d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14831 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:5afd1da0-6b31-11ec-b3df-0242ac110002 UniProtKB:O15303 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5afd465e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14416 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:5afd6f8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43003 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5afd9866-6b31-11ec-b3df-0242ac110002 UniProtKB:P43004 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:5afdc156-6b31-11ec-b3df-0242ac110002 UniProtKB:P43005 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:5afdea28-6b31-11ec-b3df-0242ac110002 UniProtKB:P19491 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5afe135e-6b31-11ec-b3df-0242ac110002 UniProtKB:P42263 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.595']} DrugCentral uuid:5afe3c26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16099 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.738']} DrugCentral uuid:5afe6502-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14832 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid is agonist of GPCR (Metabotropic glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5afe8df2-6b31-11ec-b3df-0242ac110002 UniProtKB:O00222 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid is agonist of GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5afeb9e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5afee504-6b31-11ec-b3df-0242ac110002 UniProtKB:P42260 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5aff0de0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22756 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5aff36b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31423 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5aff5fc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35349 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5aff887e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19490 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5affb13c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19492 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5affda86-6b31-11ec-b3df-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5b000402-6b31-11ec-b3df-0242ac110002 UniProtKB:P42264 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.31']} DrugCentral uuid:5b002cd4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03469 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutamate racemase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5b0055b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P70579 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5b007f86-6b31-11ec-b3df-0242ac110002 UniProtKB:P47743 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5b00a83a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31424 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:5b00d0ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P23385 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5b00f9a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31421 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5b0122a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31422 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets GPCR (Metabotropic glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5b014b64-6b31-11ec-b3df-0242ac110002 UniProtKB:P56068 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Enzyme (Glutamate racemase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5b017440-6b31-11ec-b3df-0242ac110002 UniProtKB:O35921 biolink:molecularly_interacts_with DrugCentral:1310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamic acid targets Transporter (Excitatory amino acid transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5b019d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z1J7 biolink:molecularly_interacts_with DrugCentral:1311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutamine targets Transporter (Amino acid transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5b01c6ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2Q3 biolink:molecularly_interacts_with DrugCentral:1312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutathione targets Enzyme (Glutathione S-transferase kappa 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5b01f73a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutethimide is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5b01f73a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutethimide is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5b01f73a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glutethimide is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5b023088-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:5b025a54-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5b028434-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is inhibitor of Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.795']} DrugCentral uuid:5b02acf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5b02d5ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5b030300-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:5b030300-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:5b03392e-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5b036200-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61743 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5b038b9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96P20 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Unclassified (NACHT, LRR and PYD domains-containing protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5b03b476-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:5b03dd52-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide targets Nuclear other (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5b040a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ESQ5 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is inhibitor of Ion channel (Sur1-Trpm4; Sulfonylurea receptor 1 - Transient receptor potential melastatin 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:5b040a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ESQ5 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is inhibitor of Ion channel (Sur1-Trpm4; Sulfonylurea receptor 1 - Transient receptor potential melastatin 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:5b04451c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.523']} DrugCentral uuid:5b04451c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glibenclamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.523']} DrugCentral uuid:5b047a0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5b04a2d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48067 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Transporter (Sodium- and chloride-dependent glycine transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5b04e2a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5b04e2a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5b04e2a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5b04e2a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5b04e2a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5b04e2a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5b04e2a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5b055344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:1319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycine targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:5b057d9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P80365 biolink:molecularly_interacts_with DrugCentral:1325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycyrrhizic acid targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5b05a678-6b31-11ec-b3df-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:1325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycyrrhizic acid targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5b05cf54-6b31-11ec-b3df-0242ac110002 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:1325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycyrrhizic acid targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5b05f8a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:1325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycyrrhizic acid targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.06']} DrugCentral uuid:5b062580-6b31-11ec-b3df-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:1327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 goserelin targets GPCR (Lutropin-choriogonadotropic hormone receptor) DrugCentral uuid:5b064a74-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 goserelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) DrugCentral uuid:5b066f04-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5b06983a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:5b06c102-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5b06e9de-6b31-11ec-b3df-0242ac110002 UniProtKB:P10415 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Cytosolic other (Apoptosis regulator Bcl-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5b07129c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07820 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Cytosolic other (Induced myeloid leukemia cell differentiation protein Mcl-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5b073c18-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07817 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Cytosolic other (Bcl-2-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:5b0764e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00346 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Malate dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5b078d94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0PJ46 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Lactate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:5b07b648-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6VVP7 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Malate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:5b07e122-6b31-11ec-b3df-0242ac110002 UniProtKB:P11708 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Malate dehydrogenase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5b080b16-6b31-11ec-b3df-0242ac110002 UniProtKB:P00338 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (L-lactate dehydrogenase A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5b083406-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92843 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Cytosolic other (Apoptosis regulator Bcl-W) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:5b085cec-6b31-11ec-b3df-0242ac110002 UniProtKB:P52732 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (Kinesin-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:5b088640-6b31-11ec-b3df-0242ac110002 UniProtKB:P11166 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Transporter (Solute carrier family 2, facilitated glucose transporter member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5b08af08-6b31-11ec-b3df-0242ac110002 UniProtKB:P29372 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (DNA-3-methyladenine glycosylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5b08d7ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P07195 biolink:molecularly_interacts_with DrugCentral:1328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gossypol targets Enzyme (L-lactate dehydrogenase B chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5b0900c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.428']} DrugCentral uuid:5b092b7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b095476-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5b097e42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5b09abce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:5b09abce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:5b09e4c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:5b09e4c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:5b0a19a6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5b0a4318-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 granisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:5b0a6c08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5b0a98cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:5b0a98cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:5b0acba8-6b31-11ec-b3df-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5b0acba8-6b31-11ec-b3df-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grepafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5b0afb78-6b31-11ec-b3df-0242ac110002 UniProtKB:P10875 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin targets Structural (Tubulin beta chain) DrugCentral uuid:5b0b2012-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5b0b48c6-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5b0b7a4e-6b31-11ec-b3df-0242ac110002 UniProtKB:F2SZD3 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin is inhibitor of Structural (Tubulin) DrugCentral uuid:5b0b7a4e-6b31-11ec-b3df-0242ac110002 UniProtKB:F2SZD3 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin is inhibitor of Structural (Tubulin) DrugCentral uuid:5b0b7a4e-6b31-11ec-b3df-0242ac110002 UniProtKB:F2SZD3 biolink:molecularly_interacts_with DrugCentral:1331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 griseofulvin is inhibitor of Structural (Tubulin) DrugCentral uuid:5b0bb428-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guaiacol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:5b0bdd9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guaiacol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5b0c069e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanadrel is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:5b0c2bc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanadrel targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5b0c5036-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:5b0c74c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine is substrate of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:5b0c9938-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5b0cbe04-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:5b0ce26c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:5b0d06e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-1D adrenergic receptor) DrugCentral uuid:5b0d2b64-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanethidine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:5b0d5224-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.065']} DrugCentral uuid:5b0d7c04-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.875']} DrugCentral uuid:5b0da4e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.119']} DrugCentral uuid:5b0dcdbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.926']} DrugCentral uuid:5b0df738-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5b0e1ff6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.263']} DrugCentral uuid:5b0e48e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5b0e71d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:5b0e9b2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanfacine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.164']} DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b0f5722-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:1344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanidine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b114dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1348 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halazepam is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b121016-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ulobetasol propionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5b123528-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halofantrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5b125dfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5b1286e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.003']} DrugCentral uuid:5b12afb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5b12d96a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is inverse agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:5b130246-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.947']} DrugCentral uuid:5b132b36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:5b1353fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5b137d52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5b13a610-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5b13ceec-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5b13f7c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5b14211c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5b144a98-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5b147356-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5b149c3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5b14c8b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5b14f47a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.45']} DrugCentral uuid:5b15204e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5b154a42-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.319']} DrugCentral uuid:5b157332-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is inverse agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5b159bfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5b15c5e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5b15ef1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.999']} DrugCentral uuid:5b161800-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5b1640be-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5b16699a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.182']} DrugCentral uuid:5b1693c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.569']} DrugCentral uuid:5b16bc9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5b16e564-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5b170f80-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:5b1738f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:5b1769ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5b1769ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5b1769ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5b17aa94-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.648']} DrugCentral uuid:5b17d3ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5b17fc9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5b182582-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5b184f94-6b31-11ec-b3df-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5b1879d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.305']} DrugCentral uuid:5b18a2b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:5b18cb9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5b18f520-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.76']} DrugCentral uuid:5b191df2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5b1946ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5b196faa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5b199a0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5b19c310-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5b19ebec-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:5b1a14c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5b1a4114-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:5b1a6d38-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5b1a981c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5b1ac1ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5b1aea88-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5b1b1332-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5b1b3c0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5b1b6616-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5b1b8f06-6b31-11ec-b3df-0242ac110002 UniProtKB:P52702 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:5b1bb7ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5b1be0b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5b1c0aee-6b31-11ec-b3df-0242ac110002 UniProtKB:P50130 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:5b1c33e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:5b1c5cce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5b1c85a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P50129 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5b1caeea-6b31-11ec-b3df-0242ac110002 UniProtKB:P52703 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5b1cd7d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5b1d00a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P62744 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Unclassified (AP-2 complex subunit sigma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:5b1d3946-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5b1d3946-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5b1d3946-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5b1d3946-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5b1d3946-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5b1d9fb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5b1d9fb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5b1d9fb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5b1d9fb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5b1dfb10-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5b1dfb10-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5b1dfb10-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5b1dfb10-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5b1e4f48-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5b1e4f48-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5b1e4f48-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5b1e9462-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5b1e9462-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5b1ed832-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b1ed832-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b1ed832-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b1ed832-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b1ed832-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b1f3a34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5b1f3a34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5b1f3a34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5b1f82a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:5b1f82a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:5b1f82a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:5b1fe2f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5b1fe2f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5b1fe2f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5b1fe2f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5b1fe2f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5b1fe2f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5b1fe2f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5b1fe2f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5b206788-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:5b206788-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:5b206788-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:5b20a856-6b31-11ec-b3df-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5b20d132-6b31-11ec-b3df-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:5b20fa9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5b212380-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U3Y7 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Unclassified (Sigma intracellular receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b214c66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60493 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol targets Unclassified (Zinc finger protein 664) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:5b217682-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol is inverse agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.42']} DrugCentral uuid:5b21a0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halopredone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5b21c560-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5b21ee3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.339']} DrugCentral uuid:5b2217ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.366']} DrugCentral uuid:5b2240a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.561']} DrugCentral uuid:5b226a10-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:5b229300-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.866']} DrugCentral uuid:5b22bc36-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:5b22e512-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5b230ec0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:5b2337b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.231']} DrugCentral uuid:5b2361f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.805']} DrugCentral uuid:5b238abc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5b23b398-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.338']} DrugCentral uuid:5b23dc6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.309']} DrugCentral uuid:5b2405f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14376 biolink:molecularly_interacts_with DrugCentral:1355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloprogin targets Enzyme (UDP-glucose 4-epimerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5b242ed6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:5b245366-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:5b2477f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:5b249cf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:5b24c17a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:5b24e9de-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:5b24e9de-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b255540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halothane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b2616e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P01008 biolink:molecularly_interacts_with DrugCentral:1358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 heparin is activator of Secreted (Antithrombin-III) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5b263fd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:1358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 heparin targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.14']} DrugCentral uuid:5b26693a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:1358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 heparin targets Unclassified (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.14']} DrugCentral uuid:5b269284-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:5b26bc8c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:5b26e572-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:5b270fa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5b273888-6b31-11ec-b3df-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5b276150-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5b278a2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5b27b394-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5b27dc5c-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:1362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hesperetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5b281820-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5b281820-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5b281820-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5b281820-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5b281820-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5b281820-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9RET4 biolink:molecularly_interacts_with DrugCentral:1363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hetacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5b2870d6-6b31-11ec-b3df-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.212']} DrugCentral uuid:5b289a3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.191']} DrugCentral uuid:5b28c2fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.043']} DrugCentral uuid:5b28efac-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.686']} DrugCentral uuid:5b291982-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.636']} DrugCentral uuid:5b294272-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.441']} DrugCentral uuid:5b296c02-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.618']} DrugCentral uuid:5b2994d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.994']} DrugCentral uuid:5b29bebe-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.442']} DrugCentral uuid:5b29e7b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:5b2a110c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.521']} DrugCentral uuid:5b2a39fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:5b2a62ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.882']} DrugCentral uuid:5b2a8ba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.126']} DrugCentral uuid:5b2ab76a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.911']} DrugCentral uuid:5b2ae30c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06149 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (D-lactate dehydrogenase) DrugCentral uuid:5b2b07e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.614']} DrugCentral uuid:5b2b30be-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.459']} DrugCentral uuid:5b2b5a62-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.479']} DrugCentral uuid:5b2b832a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5b2babfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.605']} DrugCentral uuid:5b2bd53c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.057']} DrugCentral uuid:5b2bfe04-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:5b2c26fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.479']} DrugCentral uuid:5b2c4fe4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.708']} DrugCentral uuid:5b2c7960-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AEK4 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) DrugCentral uuid:5b2c9ddc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:5b2cc6e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (Transitional endoplasmic reticulum ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5b2cf0e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11142 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (Heat shock cognate 71 kDa protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:5b2d1a82-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMV8 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (Heat shock 70 kDa protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:5b2d4354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5b2d6c1c-6b31-11ec-b3df-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:5b2d94ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5b2dbf28-6b31-11ec-b3df-0242ac110002 UniProtKB:P14174 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (Macrophage migration inhibitory factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5b2de89a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6IQ20 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene is inhibitor of Unclassified (N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:5b2e11a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11021 biolink:molecularly_interacts_with DrugCentral:1364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexachlorophene targets Unclassified (78 kDa glucose-regulated protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5b2e3a7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexafluronium is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:5b2e628e-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexafluronium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5b2e8c96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:1365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexafluronium targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5b2eb946-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5b2eb946-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5b2ef2c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5b2ef2c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5b2f2b7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:5b2f2b7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:5b2f6bca-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5b2f6bca-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5b2f6bca-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5b2f6bca-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5b2fb918-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5b2fe1ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamethonium is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:5b300ac6-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1368 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexestrol is antagonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:5b303c3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5b303c3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5b303c3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5b307d3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5b307d3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5b307d3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5b30beee-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5b30beee-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5b30beee-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5b310106-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5b310106-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5b310106-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5b314206-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobendine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5b314206-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobendine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5b314206-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexobendine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5b318356-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5b31a7f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5b31d0e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:5b31faac-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5b3224c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5b324dae-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexocyclium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5b327e64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylcaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5b327e64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylcaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5b327e64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylcaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5b32bfdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylresorcinol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5b32e8a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:1374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylresorcinol targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5b331176-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexylresorcinol targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5b333aca-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine is agonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5b3363c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5b338cb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5b33b590-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.508']} DrugCentral uuid:5b33df52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:5b34081a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5b34327c-6b31-11ec-b3df-0242ac110002 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5b345b30-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5b34848e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5b34ad74-6b31-11ec-b3df-0242ac110002 UniProtKB:P58406 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:5b34d65a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q91ZY2 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5b34ffae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q91ZY1 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5b352894-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JI35 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.84']} DrugCentral uuid:5b35515c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q91ZY3 biolink:molecularly_interacts_with DrugCentral:1375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histamine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5b357a56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histidine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5b35a4f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:5b35ce48-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:5b35f756-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:5b362032-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:5b3649c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homatropine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:5b3672bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P27695 biolink:molecularly_interacts_with DrugCentral:1383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hycanthone targets Enzyme (DNA-(apurinic or apyrimidinic site) lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:5b369b98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5b36c44c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:5b36e936-6b31-11ec-b3df-0242ac110002 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (DNA (cytosine-5)-methyltransferase 1) DrugCentral uuid:5b370da8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:5b37321a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBC3 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (DNA (cytosine-5)-methyltransferase 3B) DrugCentral uuid:5b3756b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5b3781c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.438']} DrugCentral uuid:5b37aab0-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5b37d3a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5b37fc90-6b31-11ec-b3df-0242ac110002 UniProtKB:P80025 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5b382602-6b31-11ec-b3df-0242ac110002 UniProtKB:B0LPN4 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine targets Ion channel (Ryanodine receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.152']} DrugCentral uuid:5b384fd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92736 biolink:molecularly_interacts_with DrugCentral:1384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydralazine is blocker of Ion channel (Ryanodine receptor 2) DrugCentral uuid:5b387454-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5b389e84-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7.01']} DrugCentral uuid:5b38c7c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5b38f0b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase 4) DrugCentral uuid:5b39153a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:5b3939ca-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5b396436-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5b398d1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5b39b60c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:5b39df9c-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochlorothiazide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:5b3a0936-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocodone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.02']} DrugCentral uuid:5b3a321c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocodone is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5b3a5b16-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortamate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5b3a8014-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5b3aa8e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Cytosolic other (Annexin A1) DrugCentral uuid:5b3acd6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone is agonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.95']} DrugCentral uuid:5b3af634-6b31-11ec-b3df-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5b3b2078-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.881']} DrugCentral uuid:5b3b49fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5b3b72f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:1388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.37']} DrugCentral uuid:5b3b9c10-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone cypionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5b3bc172-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroflumethiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7.37']} DrugCentral uuid:5b3bea3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:5b3c1334-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:5b3c3c1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5b3c71bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5b3c71bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5b3c71bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5b3c71bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydromorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5b3cbe56-6b31-11ec-b3df-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:1394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyamfetamine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.1']} DrugCentral uuid:5b3ce7dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:1394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5b3d10f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyamfetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.529']} DrugCentral uuid:5b3d39e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5b3d62de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5b3d8c32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:5b3db0cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.14']} DrugCentral uuid:5b3dd9b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.81']} DrugCentral uuid:5b3e0284-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.979']} DrugCentral uuid:5b3e2c0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5b3e54e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5b3e7dcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5b3ea6b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5b3ed038-6b31-11ec-b3df-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:5b3ef4b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:5b3f1eda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYK1 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine is antagonist of Membrane receptor (Toll-like receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:5b3f47b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NR96 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine is antagonist of Membrane receptor (Toll-like receptor 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5b3f7182-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5BJF2 biolink:molecularly_interacts_with DrugCentral:1395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxychloroquine targets Enzyme (Transmembrane protein 97) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5b3f9a54-6b31-11ec-b3df-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:1398 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxystilbamidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:5b3fc312-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5b3febda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5b401664-6b31-11ec-b3df-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase large subunit) DrugCentral uuid:5b403b12-6b31-11ec-b3df-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide is inhibitor of Enzyme (Ribonucleoside-diphosphate reductase subunit M2) DrugCentral uuid:5b405f98-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxycarbamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:5b40886a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5b40b204-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5b40dae0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5b4103bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.409']} DrugCentral uuid:5b412c98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:1400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyzine targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5b4155c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:5b417e96-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5b41a75e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5b41d102-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5b41fa06-6b31-11ec-b3df-0242ac110002 UniProtKB:P37058 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Testosterone 17-beta-dehydrogenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5b4222c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hymecromone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:5b424ba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5b427652-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5b42a294-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:5b42cda0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:5b42f67c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hyoscyamine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:5b431fd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:1404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibandronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:5b4348b6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95749 biolink:molecularly_interacts_with DrugCentral:1404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibandronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5b4371a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02769 biolink:molecularly_interacts_with DrugCentral:1404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibandronic acid targets Enzyme (Squalene synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5b439a82-6b31-11ec-b3df-0242ac110002 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:1404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibandronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5b43c3fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:1406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5b43ecda-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:1406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:5b4416b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:5b444040-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08493 biolink:molecularly_interacts_with DrugCentral:1406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibudilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5b446912-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5b4491f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5b44bab6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5b44e400-6b31-11ec-b3df-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:5b450cbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:5b453612-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:5b455aac-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:5b458446-6b31-11ec-b3df-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5b45ada4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5b45d798-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5b46007e-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5b462c2a-6b31-11ec-b3df-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5b46563c-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5b467f22-6b31-11ec-b3df-0242ac110002 UniProtKB:P02769 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Secreted (Serum albumin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5b46a7e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5b46d120-6b31-11ec-b3df-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5b46f9f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5b4726b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5b4726b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5b475c30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N695 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen is inhibitor of Transporter (Sodium-coupled monocarboxylate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5b47850c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VD48 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen targets Enzyme (Dehydrogenase/reductase SDR family member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5b47adde-6b31-11ec-b3df-0242ac110002 UniProtKB:P78348 biolink:molecularly_interacts_with DrugCentral:1407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuprofen is blocker of Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.53']} DrugCentral uuid:5b47d6a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuproxam targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5b480504-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuproxam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5b480504-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibuproxam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5b4839e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibutilide is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5b4862e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O75907 biolink:molecularly_interacts_with DrugCentral:1413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icosapent ethyl is inhibitor of Enzyme (Diacylglycerol O-acyltransferase 1) DrugCentral uuid:5b4887cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idarubicin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5b48ac66-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idarubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:5b48d0ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idarubicin targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:5b48f554-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idebenone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.155']} DrugCentral uuid:5b491e8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idebenone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:5b49475c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idebenone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5b49702e-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idebenone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:5b4998f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:1417 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idoxuridine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:5b49c31c-6b31-11ec-b3df-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:1417 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idoxuridine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5b49ee50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5b4a1736-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.41']} DrugCentral uuid:5b4a4008-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5b4a6970-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5b4a9242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5b4abb14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5b4ae3fa-6b31-11ec-b3df-0242ac110002 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:5b4b0d3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:5b4b3616-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b4b5f88-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5b4b8850-6b31-11ec-b3df-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5b4bb488-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5b4bdd64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.99']} DrugCentral uuid:5b4c0b22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5b4c0b22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5b4c484e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5b4c484e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5b4c484e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5b4c8a48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00960 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate [NMDA] receptor subunit epsilon 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5b4cb342-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60490 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Unclassified (3-beta-hydroxysteroid-delta(8),delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.57']} DrugCentral uuid:5b4cdcaa-6b31-11ec-b3df-0242ac110002 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:5b4d059a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5b4d2e76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5b4d5752-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U3Y7 biolink:molecularly_interacts_with DrugCentral:1419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ifenprodil targets Unclassified (Sigma intracellular receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:5b4d81f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5b4daaa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5b4dd376-6b31-11ec-b3df-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:5b4dfc66-6b31-11ec-b3df-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5b4e25f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5b4e4edc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5b4e77c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5b4ea12a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5b4eca10-6b31-11ec-b3df-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5b4ef300-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62053 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5b4f1bdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5b4f4620-6b31-11ec-b3df-0242ac110002 UniProtKB:P32240 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5b4f6f06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62928 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5b4f97d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43252 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5b4fc1c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43253 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.16']} DrugCentral uuid:5b4feb3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:5b501406-6b31-11ec-b3df-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:1422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5b503cd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5b5065a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:5b508efe-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:5b50b7ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.714']} DrugCentral uuid:5b50e0ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5b510992-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:5b512f94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5b51585c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5b518138-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5b51ab7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5b51d44e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:5b51fd34-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5b522624-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5b524f78-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:5b527868-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5b52a144-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5b52ca2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.69']} DrugCentral uuid:5b52f572-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5b531e62-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5b534748-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:5b537024-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5b5399aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5b53c36c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5b53ec5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5b54154c-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5b543ea0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5b5467d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5b5490a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5b54ba88-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5b54e6de-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:5b551302-6b31-11ec-b3df-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5b553c24-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5b5565a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5b558e90-6b31-11ec-b3df-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5b55b762-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5b55e048-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5b56097e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5b563264-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5b565b2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5b568412-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:5b56af28-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5b56d804-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5b5700fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5b572a7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5b575356-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5b577c32-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5b57a4fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:5b57cf20-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5b57f7f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5b5820c4-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5b584a04-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5b587506-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5b589e32-6b31-11ec-b3df-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5b58c704-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:5b58efd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5b59197a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15046 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Lysine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5b594260-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5b596b32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:5b599404-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5b59bd58-6b31-11ec-b3df-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:5b59e760-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5b5a103c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5b5a3a58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5b5a660e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5b5a8eea-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5b5ab7c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5b5ae156-6b31-11ec-b3df-0242ac110002 UniProtKB:P00520 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.97']} DrugCentral uuid:5b5b0a28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:5b5b32fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5b5b5bd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5b5b850c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5b5badde-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5b5bd7b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5b5c007c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5b5c2e6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5b5c2e6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5b5c671a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5b5c671a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5b5c9fd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5b5c9fd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5b5cd588-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05030 biolink:molecularly_interacts_with DrugCentral:1423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imatinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:5b5cfe78-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imidapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5b5d2736-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem targets Enzyme (Penicillin-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5b5d5080-6b31-11ec-b3df-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem targets Enzyme (Penicillin-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5b5d7934-6b31-11ec-b3df-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5b5da21a-6b31-11ec-b3df-0242ac110002 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5b5de2f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5b5de2f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5b5de2f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5b5de2f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5b5de2f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5b5de2f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5b5de2f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5b5e458a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:5b5e6e52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.284']} DrugCentral uuid:5b5e97f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5b5ec168-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.854']} DrugCentral uuid:5b5eea58-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.432']} DrugCentral uuid:5b5f137a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.237']} DrugCentral uuid:5b5f3e36-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.825']} DrugCentral uuid:5b5f66fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:5b5f8fda-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.495']} DrugCentral uuid:5b5fbb2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5b5fe408-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.412']} DrugCentral uuid:5b600ce4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.614']} DrugCentral uuid:5b6035a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:5b605fa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:5b60887c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:5b60b158-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:5b60da2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.081']} DrugCentral uuid:5b6103d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.071']} DrugCentral uuid:5b612cc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.36']} DrugCentral uuid:5b615586-6b31-11ec-b3df-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5b617e4e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5b61a874-6b31-11ec-b3df-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5b61d146-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:5b61fa2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:5b6223bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5b624cfc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:5b6275e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5b629ec8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34968 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5b62c826-6b31-11ec-b3df-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:5b62f10c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60857 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5b6319d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:5b6343a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5b636eac-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5b6397ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:5b63d7de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5b63d7de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5b63d7de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5b63d7de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5b63d7de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5b63d7de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5b63d7de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5b645844-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5b645844-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5b645844-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5b645844-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5b645844-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b64e282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5b65b1b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5b65b1b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5b65b1b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5b66023e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5b66023e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5b66023e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5b66023e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5b66023e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5b6662d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:5b6662d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:5b6662d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:5b66ac20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5b66ac20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5b66ac20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5b66f45a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5b66f45a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5b66f45a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5b6736ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P48545 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5b675fa8-6b31-11ec-b3df-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5b678898-6b31-11ec-b3df-0242ac110002 UniProtKB:P17405 biolink:molecularly_interacts_with DrugCentral:1427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imipramine targets Enzyme (Sphingomyelin phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5b67b1b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imiquimod targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.525']} DrugCentral uuid:5b67db68-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imiquimod targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:5b680444-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imiquimod targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5b682d34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYK1 biolink:molecularly_interacts_with DrugCentral:1429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imiquimod is agonist of Membrane receptor (Toll-like receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:5b68564c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:1431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 incadronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5b687f00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8MTZ4 biolink:molecularly_interacts_with DrugCentral:1431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 incadronic acid targets Unclassified (Vacuolar-type proton translocating pyrophosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:5b68a7e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:1431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 incadronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.523']} DrugCentral uuid:5b68d0a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indalpine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b68fc1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5b692504-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7.54']} DrugCentral uuid:5b694dc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:5b697716-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:5b699ff2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:5b69c8e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5b69f2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P51787 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Ion channel (Potassium voltage-gated channel subfamily KQT member 1) DrugCentral uuid:5b6a17d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5b6a40a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:5b6a6982-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:5b6a9286-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5b6abcf2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5b6ae826-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.535']} DrugCentral uuid:5b6b10f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5b6b39d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indapamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:5b6b6364-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indecainide is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5b6b87d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indenolol targets GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:5b6bac3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indenolol targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:5b6bd0ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:5b6bfae0-6b31-11ec-b3df-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.222']} DrugCentral uuid:5b6c2394-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.733']} DrugCentral uuid:5b6c4c66-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5b6c75d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:5b6c9f68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:5b6cc8bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5b6cf184-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5b6d1aba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.27']} DrugCentral uuid:5b6d4454-6b31-11ec-b3df-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:5b6d6d26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:1437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.42']} DrugCentral uuid:5b6d960c-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1438 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indisetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5b6dbf4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indobufen targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:5b6de3d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indobufen targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:5b6e084e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:5b6e312a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5b6e5b50-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5b6e8422-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5b6ead08-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:5b6ed5b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.53']} DrugCentral uuid:5b6eff10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BPW9 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Dehydrogenase/reductase SDR family member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5b6f27ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5b6f5082-6b31-11ec-b3df-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5b6f794a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5b6fa28a-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:5b6fcb52-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.691']} DrugCentral uuid:5b6ff42e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:5b701e22-6b31-11ec-b3df-0242ac110002 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5b70488e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5b707156-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5b709a1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5b70c412-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.19']} DrugCentral uuid:5b70ed7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b711642-6b31-11ec-b3df-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5b713f14-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5b716872-6b31-11ec-b3df-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5b719130-6b31-11ec-b3df-0242ac110002 UniProtKB:P35355 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5b71b9ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5b71e2d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5b720cf0-6b31-11ec-b3df-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.39']} DrugCentral uuid:5b723996-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5b723996-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5b7272d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5b7272d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5b72ac00-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase (cyclooxygenase)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5b72ac00-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin G/H synthase (cyclooxygenase)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5b72e0da-6b31-11ec-b3df-0242ac110002 UniProtKB:P29477 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5b730a38-6b31-11ec-b3df-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:5b73330a-6b31-11ec-b3df-0242ac110002 UniProtKB:P17516 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Aldo-keto reductase family 1 member C4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:5b735c36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin is agonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5b738526-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:1440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indomethacin targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:5b73ae16-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoprofen targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5b73d8f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08659 biolink:molecularly_interacts_with DrugCentral:1442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoprofen targets Unclassified (Luciferin 4-monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5b7402c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:5b742bac-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:5b745474-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5b747dfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:5b74a6ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:5b74cf80-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5b74f848-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5b752192-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5b754a6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5b757afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5b757afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5b757afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5b75c408-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:5b75c408-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:5b75c408-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indoramin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.61']} DrugCentral uuid:5b7604c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 intoplicine targets Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5b762d94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q969P6 biolink:molecularly_interacts_with DrugCentral:1446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 intoplicine targets Enzyme (DNA topoisomerase I, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5b7656f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:1446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 intoplicine targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5b767fba-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.278']} DrugCentral uuid:5b76a88c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.724']} DrugCentral uuid:5b76d276-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.609']} DrugCentral uuid:5b76fbac-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.804']} DrugCentral uuid:5b77246a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.067']} DrugCentral uuid:5b774d50-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.279']} DrugCentral uuid:5b77771c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.439']} DrugCentral uuid:5b77a214-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.043']} DrugCentral uuid:5b77caf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.532']} DrugCentral uuid:5b77f3cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:1457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diiodohydroxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:5b781d20-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:5b784606-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:5b786eec-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.292']} DrugCentral uuid:5b789854-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.181']} DrugCentral uuid:5b78c194-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:5b78ea7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:5b791342-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:5b793c1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.74']} DrugCentral uuid:5b7965d6-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipratropium targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.824']} DrugCentral uuid:5b798ebc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipriflavone targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.531']} DrugCentral uuid:5b79b78e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipriflavone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:5b79e074-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iprindole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5b7a09aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iprindole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.899']} DrugCentral uuid:5b7a327c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iprindole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:5b7a5b44-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iprindole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.185']} DrugCentral uuid:5b7a8434-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:1480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iproniazid targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5b7aad92-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:1480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iproniazid targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5b7ad66e-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iproniazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5b7aff40-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iproniazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:5b7b2830-6b31-11ec-b3df-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5b7b52f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5b7b7cc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5b7ba968-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5b7ba968-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5b7be658-6b31-11ec-b3df-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5b7be658-6b31-11ec-b3df-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5b7be658-6b31-11ec-b3df-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5b7c2712-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:1481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irbesartan is inhibitor of Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5b7c4fda-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5b7c7514-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.664']} DrugCentral uuid:5b7c9de6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:5b7cc262-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.336']} DrugCentral uuid:5b7ceb34-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:5b7d11c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:5b7d36f2-6b31-11ec-b3df-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:5b7d5c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5b7d8594-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan is inhibitor of Enzyme (DNA topoisomerase 1) DrugCentral uuid:5b7daa7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.218']} DrugCentral uuid:5b7dd35a-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5b7dfc22-6b31-11ec-b3df-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:5b7e2512-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5b7e4e98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5b7e776a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5b7ea046-6b31-11ec-b3df-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irinotecan targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:5b7ec918-6b31-11ec-b3df-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:1483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 irofulven targets Kinase (Serine/threonine-protein kinase Chk2) DrugCentral uuid:5b7ef050-6b31-11ec-b3df-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:1486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isepamicin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.87']} DrugCentral uuid:5b7f1936-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1490 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isocarboxazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:5b7f3dbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1490 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isocarboxazid is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:5b7f6350-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoetarine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5b7f8ca4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.109']} DrugCentral uuid:5b7fb594-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:5b7fda2e-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:5b7ffeb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:5b8023e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:5b80487e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:5b8070d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:5b8070d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive modulator of Ion channel (Glycine receptor (alpha-1/beta)) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b80da46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5b819a62-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5b81c348-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5b81ecce-6b31-11ec-b3df-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.15']} DrugCentral uuid:5b8215aa-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:5b824106-6b31-11ec-b3df-0242ac110002 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5b8269d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q29550 biolink:molecularly_interacts_with DrugCentral:1494 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluostigmine targets Enzyme (Liver carboxylesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5b8294f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5b82be06-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WIE4 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Catalase-peroxidase) DrugCentral uuid:5b82e2b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5b830b86-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5b8334bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5b835d7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WNX1 biolink:molecularly_interacts_with DrugCentral:1497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoniazid targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5b838656-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5b83af28-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.8']} DrugCentral uuid:5b83d886-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5b840176-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5b842a48-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5b8453ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5b847cc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.752']} DrugCentral uuid:5b84a57c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:5b84ce12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5b84f748-6b31-11ec-b3df-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5b852010-6b31-11ec-b3df-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5b854982-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYV8 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 14) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b857254-6b31-11ec-b3df-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b859bc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04274 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:5b85c4b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5b85ed9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5b861664-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5b86415c-6b31-11ec-b3df-0242ac110002 UniProtKB:P59533 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 38) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b866b28-6b31-11ec-b3df-0242ac110002 UniProtKB:P59534 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 39) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b8693fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P59535 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 40) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b86bcae-6b31-11ec-b3df-0242ac110002 UniProtKB:P59536 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 41) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b86e5ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P59537 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 43) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b870eac-6b31-11ec-b3df-0242ac110002 UniProtKB:P59538 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 31) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b873792-6b31-11ec-b3df-0242ac110002 UniProtKB:P59539 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 45) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b8760c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b8789ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P59541 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 30) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b87b276-6b31-11ec-b3df-0242ac110002 UniProtKB:P59542 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 19) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b87db52-6b31-11ec-b3df-0242ac110002 UniProtKB:P59543 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b880578-6b31-11ec-b3df-0242ac110002 UniProtKB:P59544 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 50) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b882e86-6b31-11ec-b3df-0242ac110002 UniProtKB:P59551 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 60) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b885758-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7RTR8 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 42) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b88802a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYV7 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 16) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b88a992-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYV8 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 14) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b88d264-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYV9 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 13) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b88fb36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYW0 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b89253e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYW1 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b894e60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYW2 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b897746-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYW3 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b89a0a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYW4 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b89c980-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYW5 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b89f5fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYW6 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b8a2074-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYW7 biolink:molecularly_interacts_with DrugCentral:1499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoprenaline targets GPCR (Taste receptor type 2 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5b8a493c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isopropamide is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5b8a6f8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isopropamide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:5b8a9414-6b31-11ec-b3df-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:5b8ac42a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5b8ac42a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5b8ac42a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5b8ac42a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide dinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5b8b080e-6b31-11ec-b3df-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:5b8b3856-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5b8b3856-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5b8b3856-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5b8b3856-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isosorbide mononitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5b8b7c30-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:5b8ba606-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5b8bcf5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.628']} DrugCentral uuid:5b8bf840-6b31-11ec-b3df-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['8.229']} DrugCentral uuid:5b8c20f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08319 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Enzyme (Alcohol dehydrogenase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:5b8c4a84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BPW9 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Enzyme (Dehydrogenase/reductase SDR family member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.523']} DrugCentral uuid:5b8c7356-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92781 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Enzyme (11-cis retinol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5b8c9c3c-6b31-11ec-b3df-0242ac110002 UniProtKB:O14756 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Enzyme (17-beta-hydroxysteroid dehydrogenase type 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:5b8cc522-6b31-11ec-b3df-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin is inhibitor of Nuclear hormone receptor (Retinoic acid receptor beta) DrugCentral uuid:5b8cea16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.597']} DrugCentral uuid:5b8d12de-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.335']} DrugCentral uuid:5b8d3bb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P40220 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5b8d6482-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:1508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isotretinoin targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5b8d8f7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1509 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoxicam targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5b8db964-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1509 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5b8de22c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:5b8e069e-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:5b8e2cbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5b8e55c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5b8e7e94-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:5b8ea798-6b31-11ec-b3df-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:5b8ed0ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5b8ef9b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JIS7 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5b8f23a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01815 biolink:molecularly_interacts_with DrugCentral:1511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isradipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5b8f4da6-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5b8f78b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.046']} DrugCentral uuid:5b8fa1a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['9.246']} DrugCentral uuid:5b8fca9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5b8ff418-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5b901cd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5b9045bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5b906e98-6b31-11ec-b3df-0242ac110002 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5b9097d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5b90c0b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5b90e99a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5b91128a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:1513 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 itraconazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5b915b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:5b915b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:5b915b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:5b915b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:5b915b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:5b915b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:5b915b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:5b915b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:5b915b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:1517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixabepilone is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:5b91d4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:1519 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kanamycin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.678']} DrugCentral uuid:5b91fe02-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A6R0 biolink:molecularly_interacts_with DrugCentral:1519 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kanamycin targets Unclassified (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5b9226de-6b31-11ec-b3df-0242ac110002 UniProtKB:P29033 biolink:molecularly_interacts_with DrugCentral:1519 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kanamycin targets Unclassified (Gap junction beta-2 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:5b924fba-6b31-11ec-b3df-0242ac110002 UniProtKB:C3TDZ2 biolink:molecularly_interacts_with DrugCentral:1520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bekanamycin targets Enzyme (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5b92792c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A6R0 biolink:molecularly_interacts_with DrugCentral:1520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bekanamycin targets Unclassified (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:5b92a1fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5b92e1c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5b92e1c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5b92e1c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5b92e1c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5b92e1c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5b92e1c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5b92e1c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is blocker of Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5b9369f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5b9369f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5b9369f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5b9369f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5b9369f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5b9369f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5b9369f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5b93e6a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:5b93e6a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:5b93e6a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:5b93e6a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:1523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketamine is opener of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:5b942c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5b9455e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5b947eac-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki'} DrugCentral uuid:5b94a814-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5b94d1f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:5b94fb48-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5b95241a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5b954d00-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5b957672-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5b959f58-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5b95c83e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5b95f110-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5b961a50-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.701']} DrugCentral uuid:5b96432c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5b966c12-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.747']} DrugCentral uuid:5b9694f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5b96bf78-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5b96e840-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:5b9710fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:5b9739d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5b976360-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5b978c32-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5b97b50e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.903']} DrugCentral uuid:5b97de44-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:5b98072a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5b983100-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5b9859dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5b988380-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.33']} DrugCentral uuid:5b98ac52-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5b98d542-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5b98fe14-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5b99279a-6b31-11ec-b3df-0242ac110002 UniProtKB:P54219 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is inhibitor of Transporter (Chromaffin granule amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5b99580a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5b99580a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5b99580a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5b99a094-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5b99a094-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5b99a094-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5b99e19e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5b9a0bec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BRU6 biolink:molecularly_interacts_with DrugCentral:1524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketanserin targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5b9a34aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5b9a5f52-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.223']} DrugCentral uuid:5b9a881a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.585']} DrugCentral uuid:5b9ab100-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.845']} DrugCentral uuid:5b9ae544-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b9ae544-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b9ae544-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b9ae544-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5b9b3de6-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5b9b3de6-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5b9b3de6-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5b9b3de6-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1526 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketobemidone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5b9b8c1a-6b31-11ec-b3df-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.821']} DrugCentral uuid:5b9bb4ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5b9bde86-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5b9c0730-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5b9c3228-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5b9c5e10-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5b9c8714-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:5b9caff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.084']} DrugCentral uuid:5b9cd98a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.667']} DrugCentral uuid:5b9d0266-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.028']} DrugCentral uuid:5b9d2b4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:5b9d540a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.729']} DrugCentral uuid:5b9d8060-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:5b9da4dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:5b9dcdd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5b9df7b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.346']} DrugCentral uuid:5b9e22ea-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5b9e4c2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5b9e7506-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5b9e9ea0-6b31-11ec-b3df-0242ac110002 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5b9ec768-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16322 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5b9ef0a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:5b9f197a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.665']} DrugCentral uuid:5b9f43a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'app Ki', 'has_quantitative_value': ['7.197']} DrugCentral uuid:5b9f6c4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5b9f953a-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:5b9fbdf8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5b9fea08-6b31-11ec-b3df-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5ba012da-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.266']} DrugCentral uuid:5ba03bb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.897']} DrugCentral uuid:5ba06672-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.211']} DrugCentral uuid:5ba08f76-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.009']} DrugCentral uuid:5ba0b83e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:5ba0e192-6b31-11ec-b3df-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.66']} DrugCentral uuid:5ba10ac8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07973 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.506']} DrugCentral uuid:5ba133a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08686 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 21) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5ba15c6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15150 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 11B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5ba18534-6b31-11ec-b3df-0242ac110002 UniProtKB:P14137 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 11A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:5ba1b022-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09128 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 24A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5ba1d912-6b31-11ec-b3df-0242ac110002 UniProtKB:P18125 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 7A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:5ba201da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q64654 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 51) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5ba22aca-6b31-11ec-b3df-0242ac110002 UniProtKB:P11715 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (Cytochrome P450 17A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:5ba254dc-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.81']} DrugCentral uuid:5ba27db8-6b31-11ec-b3df-0242ac110002 UniProtKB:O35084 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5ba2a694-6b31-11ec-b3df-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is inhibitor of Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.174']} DrugCentral uuid:5ba2cf66-6b31-11ec-b3df-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is inhibitor of Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:5ba2f8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoconazole is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.896']} DrugCentral uuid:5ba321b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5ba34b9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:5ba37560-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5ba39ea0-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:5ba3cb46-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5ba3cb46-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketoprofen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5ba40034-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5ba429ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.72']} DrugCentral uuid:5ba452aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:5ba47b7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.214']} DrugCentral uuid:5ba4a43a-6b31-11ec-b3df-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5ba4cd8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:1529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketorolac targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5ba4f660-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.361']} DrugCentral uuid:5ba51f46-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.086']} DrugCentral uuid:5ba548ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5ba56df2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.839']} DrugCentral uuid:5ba59746-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.047']} DrugCentral uuid:5ba5c022-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:5ba5e9c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.076']} DrugCentral uuid:5ba612b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.276']} DrugCentral uuid:5ba63b88-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.489']} DrugCentral uuid:5ba66464-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.176']} DrugCentral uuid:5ba68dcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.509']} DrugCentral uuid:5ba6b694-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.391']} DrugCentral uuid:5ba6df84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5ba70978-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.016']} DrugCentral uuid:5ba7343e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.359']} DrugCentral uuid:5ba75e32-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:5ba7870e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.075']} DrugCentral uuid:5ba7afea-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.73']} DrugCentral uuid:5ba7d952-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.737']} DrugCentral uuid:5ba80242-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:5ba82b14-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1530 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ketotifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5ba85440-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.234']} DrugCentral uuid:5ba87d58-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:5ba8a63e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.117']} DrugCentral uuid:5ba8cf10-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.478']} DrugCentral uuid:5ba8f9a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.648']} DrugCentral uuid:5ba92280-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.714']} DrugCentral uuid:5ba94b48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.894']} DrugCentral uuid:5ba97424-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:5ba99d6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:5ba9c64a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.491']} DrugCentral uuid:5ba9ef3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:5baa1802-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5baa4142-6b31-11ec-b3df-0242ac110002 UniProtKB:P47154 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Enzyme (CAAX prenyl protease 1) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5baa69e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:1531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 labetalol targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5baa92a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.046']} DrugCentral uuid:5baabb72-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.245']} DrugCentral uuid:5baae58e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.679']} DrugCentral uuid:5bab0e7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.642']} DrugCentral uuid:5bab375a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5bab6162-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5bab8a34-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.771']} DrugCentral uuid:5babb392-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:5babe04c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:5babe04c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:5bac0fb8-6b31-11ec-b3df-0242ac110002 UniProtKB:O00214 biolink:molecularly_interacts_with DrugCentral:1535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lactose targets Unclassified (Galectin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.21']} DrugCentral uuid:5bac388a-6b31-11ec-b3df-0242ac110002 UniProtKB:O00182 biolink:molecularly_interacts_with DrugCentral:1535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lactose targets Unclassified (Galectin-9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bac6148-6b31-11ec-b3df-0242ac110002 UniProtKB:P17931 biolink:molecularly_interacts_with DrugCentral:1535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lactose targets Unclassified (Galectin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.03']} DrugCentral uuid:5bac89fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:1539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamivudine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:5bacb120-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:1539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamivudine is inhibitor of Polyprotein (Protein P) DrugCentral uuid:5bacd614-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1539 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamivudine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:5bacfee6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:5bad27ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.839']} DrugCentral uuid:5bad50f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:5bad7592-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5bad9e78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5badc86c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5badf1b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:5bae166e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5bae3f2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.744']} DrugCentral uuid:5bae681c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:5bae92d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5baebba0-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5baeec24-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:5baeec24-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:5baeec24-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:5baf2e46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:1540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lamotrigine targets Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5baf5704-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1545 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 landiolol is antagonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:5baf7b9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:5bafa47a-6b31-11ec-b3df-0242ac110002 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5bafcdd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5baff6c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30875 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5bb0203a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30935 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5bb04a4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide targets GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:5bb0733c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5bb09c0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide targets GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.301']} DrugCentral uuid:5bb0c4f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30680 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5bb0ee34-6b31-11ec-b3df-0242ac110002 UniProtKB:P30936 biolink:molecularly_interacts_with DrugCentral:1546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5bb1171a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.275']} DrugCentral uuid:5bb13fec-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.473']} DrugCentral uuid:5bb168aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5bb19280-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCT1 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Phosphoethanolamine/phosphocholine phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5bb1bb48-6b31-11ec-b3df-0242ac110002 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5bb1e42e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5bb210f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:5bb210f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:5bb241a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:5bb26a84-6b31-11ec-b3df-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:5bb29360-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:1547 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lansoprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5bb2bc8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5bb2e112-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:5bb30598-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5bb32f3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bb3589a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.04']} DrugCentral uuid:5bb38194-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5bb3aa66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Transporter (Solute carrier organic anion transporter family member 1B1) DrugCentral uuid:5bb3cef6-6b31-11ec-b3df-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5bb3f994-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5bb4269e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.27']} DrugCentral uuid:5bb44fd4-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5bb478b0-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5bb4a1e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5bb4cac2-6b31-11ec-b3df-0242ac110002 UniProtKB:O14733 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:5bb4f39e-6b31-11ec-b3df-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.27']} DrugCentral uuid:5bb51c84-6b31-11ec-b3df-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5bb545a6-6b31-11ec-b3df-0242ac110002 UniProtKB:O00750 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5bb56e96-6b31-11ec-b3df-0242ac110002 UniProtKB:O75747 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5bb59772-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5bb5c04e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lapatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5bb5ebbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:1549 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arginine hydrochloride targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bb614ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5T6X5 biolink:molecularly_interacts_with DrugCentral:1549 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arginine hydrochloride is agonist of GPCR (G-protein coupled receptor family C group 6 member A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5bb63d6c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75746 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Calcium-binding mitochondrial carrier protein Aralar1) DrugCentral uuid:5bb66256-6b31-11ec-b3df-0242ac110002 UniProtKB:P17174 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartate aminotransferase, cytoplasmic) DrugCentral uuid:5bb686c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P45381 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartoacylase) DrugCentral uuid:5bb6ab3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08243 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Asparagine synthetase [glutamine-hydrolyzing]) DrugCentral uuid:5bb6cfa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00966 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Argininosuccinate synthase) DrugCentral uuid:5bb6f41e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03154 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aminoacylase-1) DrugCentral uuid:5bb718fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P00505 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartate aminotransferase, mitochondrial) DrugCentral uuid:5bb73e56-6b31-11ec-b3df-0242ac110002 UniProtKB:P14868 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartate--tRNA ligase, cytoplasmic) DrugCentral uuid:5bb762e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12797 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Enzyme (Aspartyl/asparaginyl beta-hydroxylase) DrugCentral uuid:5bb78852-6b31-11ec-b3df-0242ac110002 UniProtKB:P43003 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:5bb7b304-6b31-11ec-b3df-0242ac110002 UniProtKB:P43004 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5bb7dbc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43005 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:5bb804a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UJS0 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Calcium-binding mitochondrial carrier protein Aralar2) DrugCentral uuid:5bb8409e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5bb8409e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5bb8409e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5bb8409e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5bb8409e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5bb8409e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5bb8409e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5bb8b0c4-6b31-11ec-b3df-0242ac110002 UniProtKB:O35921 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Excitatory amino acid transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5bb8d9dc-6b31-11ec-b3df-0242ac110002 UniProtKB:O59010 biolink:molecularly_interacts_with DrugCentral:1550 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aspartic acid targets Transporter (Glutamate transporter homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5bb902ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprost targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.757']} DrugCentral uuid:5bb92b80-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.187']} DrugCentral uuid:5bb95466-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5bb97fe0-6b31-11ec-b3df-0242ac110002 UniProtKB:P37289 biolink:molecularly_interacts_with DrugCentral:1551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprost targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:5bb9a916-6b31-11ec-b3df-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.287']} DrugCentral uuid:5bb9d206-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.338']} DrugCentral uuid:5bb9fae2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5bba2468-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide is inhibitor of Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5bba4e7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:5bba7756-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.684']} DrugCentral uuid:5bbaa104-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63707 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5bbaca44-6b31-11ec-b3df-0242ac110002 UniProtKB:O35435 biolink:molecularly_interacts_with DrugCentral:1552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5bbaf316-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letrozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5bbb1be8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letrozole targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:5bbb4636-6b31-11ec-b3df-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letrozole targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5bbb70fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leucine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:5bbb99e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leuprorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.523']} DrugCentral uuid:5bbbc2c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:1559 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 leuprorelin targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5bbbec12-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:5bbc14ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:5bbc3dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5bbc7204-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:5bbc7204-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:5bbc7204-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:5bbc7204-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levallorphan targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.27']} DrugCentral uuid:5bbcbf0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N587 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Ion channel (Acetylcholine receptor subunit alpha-type unc-63) DrugCentral uuid:5bbce39c-6b31-11ec-b3df-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5bbd0c82-6b31-11ec-b3df-0242ac110002 UniProtKB:O96760 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole is agonist of Ion channel (Nicotinic acetylcholine receptor alpha subunit) DrugCentral uuid:5bbd32d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.568']} DrugCentral uuid:5bbd5c50-6b31-11ec-b3df-0242ac110002 UniProtKB:P09487 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:5bbd84fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P09923 biolink:molecularly_interacts_with DrugCentral:1561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamisole targets Enzyme (Intestinal-type alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:5bbdadd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:5bbdd73e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5bbdfffc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:5bbe28c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.47']} DrugCentral uuid:5bbe52f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbeaca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamfetamine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5bbf7396-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam targets Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:5bbf986c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:5bbfbce8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:5bbfe182-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02563 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam is inhibitor of Unclassified (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5bc00a68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7L0J3 biolink:molecularly_interacts_with DrugCentral:1563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levetiracetam is modulator of Transporter (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5bc033bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5bc0586a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.279']} DrugCentral uuid:5bc0813c-6b31-11ec-b3df-0242ac110002 UniProtKB:O95665 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine is agonist of GPCR (Neurotensin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5bc0aa2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63384 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine targets GPCR (Neurotensin receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5bc0d4ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P70310 biolink:molecularly_interacts_with DrugCentral:1564 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocabastine is agonist of GPCR (Neurotensin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5bc0fda6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levocetirizine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:5bc12772-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5bc1503a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.541']} DrugCentral uuid:5bc1795c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.428']} DrugCentral uuid:5bc1a224-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.668']} DrugCentral uuid:5bc1cad8-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.646']} DrugCentral uuid:5bc1f3be-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa is agonist of GPCR (D(1A) dopamine receptor) DrugCentral uuid:5bc218c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1567 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levodopa is agonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:5bc23d56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.04']} DrugCentral uuid:5bc26650-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5bc28f0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:5bc2bce0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:5bc2bce0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59961 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin is inhibitor of Enzyme (DNA topoisomerase 4) DrugCentral uuid:5bc2efc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5bc2efc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P72524 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5bc31ea6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y256 biolink:molecularly_interacts_with DrugCentral:1569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levofloxacin targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:5bc347be-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadyl acetate is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:5bc36c3a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadyl acetate targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5bc39598-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.225']} DrugCentral uuid:5bc3be92-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.167']} DrugCentral uuid:5bc3e7dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:5bc40c62-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['12.796']} DrugCentral uuid:5bc43520-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.91']} DrugCentral uuid:5bc45dde-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.37']} DrugCentral uuid:5bc488fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levonorgestrel targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.339']} DrugCentral uuid:5bc4b1f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:5bc4daca-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:5bc503e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:5bc52dea-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5bc556b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5bc57f84-6b31-11ec-b3df-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:5bc5a8ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:5bc5d196-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5bc5fbb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5bc62498-6b31-11ec-b3df-0242ac110002 UniProtKB:O55242 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:5bc665f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5bc665f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5bc665f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5bc665f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5bc665f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5bc665f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5bc665f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5bc6ed92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5bc6ed92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5bc6ed92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5bc6ed92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5bc6ed92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5bc6ed92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5bc6ed92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5bc76920-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:5bc76920-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:5bc76920-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:5bc76920-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:5bc7bede-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5bc7bede-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5bc7bede-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5bc7ff8e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levorphanol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5bc82a72-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1575 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosalbutamol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5bc85344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosimendan targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) DrugCentral uuid:5bc877c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosimendan targets Ion channel (ATP-sensitive inward rectifier potassium channel 11) DrugCentral uuid:5bc89c3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15842 biolink:molecularly_interacts_with DrugCentral:1576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosimendan targets Ion channel (ATP-sensitive inward rectifier potassium channel 8) DrugCentral uuid:5bc8c130-6b31-11ec-b3df-0242ac110002 UniProtKB:P63316 biolink:molecularly_interacts_with DrugCentral:1576 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosimendan is opener of Cytosolic other (Troponin C, slow skeletal and cardiac muscles) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.155']} DrugCentral uuid:5bc8e9da-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:5bc912ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:5bc93b7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5bc9655e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5bc98e1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:5bc9b6da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5bc9f08c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5bc9f08c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5bc9f08c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5bc9f08c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5bc9f08c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5bca50cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5bca50cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5bca50cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5bca9b2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5bca9b2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5bca9b2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levosulpiride targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5bcadcb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5bcb05a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:5bcb2a9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5bcb536e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5bcb7c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5bcba526-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.296']} DrugCentral uuid:5bcbd050-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:5bcbf4cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.559']} DrugCentral uuid:5bcc2532-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.955']} DrugCentral uuid:5bcc2532-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.955']} DrugCentral uuid:5bcc2532-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.955']} DrugCentral uuid:5bcc6dda-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:5bcc6dda-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:5bcc6dda-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:5bccae9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5bccd766-6b31-11ec-b3df-0242ac110002 UniProtKB:P15389 biolink:molecularly_interacts_with DrugCentral:1579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidocaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5bcd007e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5bcd295a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5bcd59d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:5bcd59d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:5bcd59d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:1580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lidoflazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:5bcd9c96-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 limaprost is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) DrugCentral uuid:5bcdc11c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:1582 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lincomycin targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:5bcde5a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (Gamma-aminobutyric acid receptor subunit beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5bce0e74-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:5bce3886-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75NA5 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (Gamma-aminobutyric acid receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5bce614e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24046 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (Gamma-aminobutyric acid receptor subunit rho-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:5bce91d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:5bce91d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:5bce91d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:5bcedaf2-6b31-11ec-b3df-0242ac110002 UniProtKB:H9U2W1 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:5bcedaf2-6b31-11ec-b3df-0242ac110002 UniProtKB:H9U2W1 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:5bcedaf2-6b31-11ec-b3df-0242ac110002 UniProtKB:H9U2W1 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:5bcf1bca-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W492 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:5bcf1bca-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W492 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:5bcf1bca-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W492 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane is negative allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:5bcf5cb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5bcf5cb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5bcf5cb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA-A receptor alpha-6/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5bcfad6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:5bcfad6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:5bcfad6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:1583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lindane targets Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:5bcfee24-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linezolid targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5bd0175a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linezolid targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5bd0404a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:1584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linezolid targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5bd06912-6b31-11ec-b3df-0242ac110002 UniProtKB:P31040 biolink:molecularly_interacts_with DrugCentral:1584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linezolid targets Enzyme (Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5bd091f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine is agonist of Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.24']} DrugCentral uuid:5bd0bb60-6b31-11ec-b3df-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine is agonist of Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:5bd0e446-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5bd10d18-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:5bd135c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5bd16128-6b31-11ec-b3df-0242ac110002 UniProtKB:P12004 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Nuclear other (Proliferating cell nuclear antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5bd189e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Unclassified (THAP domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd1eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd2ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liothyronine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5bd3e15a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1587 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisinopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:5bd40a22-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1587 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisinopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:5bd432f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.491']} DrugCentral uuid:5bd45c34-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:5bd48506-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:5bd4adce-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5bd4d6b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.936']} DrugCentral uuid:5bd50224-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5bd52af6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.061']} DrugCentral uuid:5bd553d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5bd57cb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.259']} DrugCentral uuid:5bd5a5da-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5bd5cec0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.625']} DrugCentral uuid:5bd5f7a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:5bd62104-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5bd649ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:5bd673c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:5bd69c92-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5bd6c67c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5bd6ef62-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.203']} DrugCentral uuid:5bd71834-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:5bd7419c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5bd76ae6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.037']} DrugCentral uuid:5bd793c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.78']} DrugCentral uuid:5bd7bc80-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.174']} DrugCentral uuid:5bd7e566-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.338']} DrugCentral uuid:5bd80e88-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5bd8375a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5bd8602c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.33']} DrugCentral uuid:5bd888e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5bd8b3d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5bd8dcdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisuride is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.489']} DrugCentral uuid:5bd905ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5bd92f20-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:5bd95810-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.268']} DrugCentral uuid:5bd980d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:5bd9a9c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5bd9d2fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5bd9fbda-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.444']} DrugCentral uuid:5bda25ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.174']} DrugCentral uuid:5bda4ea0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.481']} DrugCentral uuid:5bda7b50-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.886']} DrugCentral uuid:5bdaa652-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.468']} DrugCentral uuid:5bdacf1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofepramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.337']} DrugCentral uuid:5bdaf7f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5bdb2172-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:5bdb4a44-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:5bdb732a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:5bdba430-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5bdba430-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5bdba430-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5bdbec88-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5bdbec88-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5bdbec88-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5bdc2d56-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lofexidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:5bdc5812-6b31-11ec-b3df-0242ac110002 UniProtKB:P43700 biolink:molecularly_interacts_with DrugCentral:1594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomefloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5bdc84cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomefloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5bdc84cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1594 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomefloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5bdcb3b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:1595 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomerizine targets Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:5bdcdcd8-6b31-11ec-b3df-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:1597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonazolac targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:5bdd05a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:5bdd2e7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5bdd574e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.824']} DrugCentral uuid:5bdd8070-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) DrugCentral uuid:5bdda4e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.578']} DrugCentral uuid:5bddce4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.932']} DrugCentral uuid:5bddf7bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:5bde239a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.343']} DrugCentral uuid:5bde4c58-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5bde7520-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.519']} DrugCentral uuid:5bde9dfc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5bdec764-6b31-11ec-b3df-0242ac110002 UniProtKB:O00555 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) DrugCentral uuid:5bdeebd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5bdf14a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.599']} DrugCentral uuid:5bdf3d70-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:5bdf6e58-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Cytosolic other (Calmodulin) DrugCentral uuid:5bdf6e58-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Cytosolic other (Calmodulin) DrugCentral uuid:5bdf6e58-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Cytosolic other (Calmodulin) DrugCentral uuid:5bdfa7b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:5bdfd082-6b31-11ec-b3df-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.345']} DrugCentral uuid:5bdffbc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2B) DrugCentral uuid:5be02172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14957 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) DrugCentral uuid:5be045e4-6b31-11ec-b3df-0242ac110002 UniProtKB:O15399 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Glutamate receptor ionotropic, NMDA 2D) DrugCentral uuid:5be06a60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:5be093f0-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:5be0bcb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.272']} DrugCentral uuid:5be0e5a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.072']} DrugCentral uuid:5be10e66-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5be13792-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:5be1605a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5be1894a-6b31-11ec-b3df-0242ac110002 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5be1bb2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5be1bb2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5be1bb2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5be1fce0-6b31-11ec-b3df-0242ac110002 UniProtKB:O00255 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Unclassified (Menin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:5be2259e-6b31-11ec-b3df-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:1599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loperamide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5be24e84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5be277d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:5be2a0a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:5be2c530-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:5be2ee8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q80W54 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Enzyme (CAAX prenyl protease 1 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:5be31756-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5be34014-6b31-11ec-b3df-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.59']} DrugCentral uuid:5be36904-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:1601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lopinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.54']} DrugCentral uuid:5be39a32-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5be39a32-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5be39a32-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5be3db0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5be3db0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5be3db0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5be41c82-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5be41c82-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5be41c82-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5be45df0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5be45df0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5be45df0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1602 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loprazolam targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5be4972a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5be4d302-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5be4d302-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5be4d302-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5be4d302-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5be4d302-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5be4d302-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5be4d302-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loracarbef is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5be537c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5be56196-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:5be58dec-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:5be5b970-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:5be5e256-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5be60bd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:5be634b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5be65d80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5be68648-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:5be6af7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5be6d864-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2J7 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Transporter (Sodium-dependent neutral amino acid transporter B(0)AT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5be70122-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loratadine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5be72a08-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorazepam targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5be75b90-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:5be75b90-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:5be75b90-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.456']} DrugCentral uuid:5be79c22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5be7c09e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:5be7e5ba-6b31-11ec-b3df-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:5be80a36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:5be82eb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:1607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcainide targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:5be85324-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.498']} DrugCentral uuid:5be87c6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5be8a52c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5be8ce08-6b31-11ec-b3df-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:5be8f6bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5be9233a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:5be94f5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5be9788a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5be9a134-6b31-11ec-b3df-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:5be9cb14-6b31-11ec-b3df-0242ac110002 UniProtKB:P34976 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5be9f3f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WV26 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5bea20a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5bea20a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5bea6146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5bea6146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5bea6146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5bea6146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5beab254-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:5beab254-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:5beaf138-6b31-11ec-b3df-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:5beaf138-6b31-11ec-b3df-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:5beaf138-6b31-11ec-b3df-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:5beb3724-6b31-11ec-b3df-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.43']} DrugCentral uuid:5beb3724-6b31-11ec-b3df-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets GPCR (Angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.43']} DrugCentral uuid:5beb6c12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCN6 biolink:molecularly_interacts_with DrugCentral:1610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 losartan targets Unclassified (Platelet glycoprotein VI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5beb9570-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loteprednol etabonate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5bebba00-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.061']} DrugCentral uuid:5bebe2e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.095']} DrugCentral uuid:5bec0bcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.807']} DrugCentral uuid:5bec3570-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5bec5e60-6b31-11ec-b3df-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.67']} DrugCentral uuid:5bec880e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5becb1a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P49019 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets GPCR (Hydroxycarboxylic acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:5becdb9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5bed0478-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5bed2db8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:5bed56ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.027']} DrugCentral uuid:5bed7fe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.697']} DrugCentral uuid:5beda8ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5bedd1d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5bedfb4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01237 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:5bee242a-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5bee4d1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P20701 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Adhesion (Leukocyte adhesion glycoprotein LFA-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5bee75e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95214 biolink:molecularly_interacts_with DrugCentral:1612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lovastatin targets Enzyme (Acyl-CoA:cholesterol acyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5bef3932-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.268']} DrugCentral uuid:5bef65c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:5bef8f5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:5befb8bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.244']} DrugCentral uuid:5befe260-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:5bf00b82-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:5bf0345e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5bf05e8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5bf088b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.509']} DrugCentral uuid:5bf0b1a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:5bf0da94-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5bf103de-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:5bf12e7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5bf15758-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.682']} DrugCentral uuid:5bf18048-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.297']} DrugCentral uuid:5bf1aa78-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5bf1d354-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.376']} DrugCentral uuid:5bf1fd2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.914']} DrugCentral uuid:5bf22606-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.087']} DrugCentral uuid:5bf2502c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.829']} DrugCentral uuid:5bf27ab6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.411']} DrugCentral uuid:5bf2a3b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5bf2cce6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:5bf2f612-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5bf31eda-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:5bf347c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.276']} DrugCentral uuid:5bf37164-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:5bf39a54-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.854']} DrugCentral uuid:5bf3c33a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5bf3ec16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5JUK3 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is activator of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:5bf415ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:5bf43ea0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5bf4675e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:5bf49080-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5bf4b9c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5bf4e27e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5bf51302-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5bf51302-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5bf51302-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5bf55632-6b31-11ec-b3df-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:1614 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxiglumide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:5bf57f04-6b31-11ec-b3df-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:1614 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxiglumide is antagonist of GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5bf5a7ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5bf5d0c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loxoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5bf5fb50-6b31-11ec-b3df-0242ac110002 UniProtKB:P27695 biolink:molecularly_interacts_with DrugCentral:1616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lucanthone targets Enzyme (DNA-(apurinic or apyrimidinic site) lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5bf62422-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1617 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumefantrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5bf64cea-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumiracoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5bf67620-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumiracoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5bf69f10-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumiracoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5bf6c7ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5bf6f10e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:5bf71a58-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.979']} DrugCentral uuid:5bf74320-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.856']} DrugCentral uuid:5bf76bde-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.12']} DrugCentral uuid:5bf794c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5bf7be90-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5bf7e776-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5bf8103e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5bf83924-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5bf86278-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5bf88b54-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.81']} DrugCentral uuid:5bf8b43a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:5bf8ddac-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:5bf90930-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5bf93220-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:5bf95b24-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5bf98518-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:5bf9b092-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5bf9d982-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5bfa0272-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61616 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5bfa2bb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5bfa5c4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5bfa5c4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5bfa5c4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5bfa9d22-6b31-11ec-b3df-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lysine targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:5bfac69e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5bfaef84-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5bfb1856-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5bfb413c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:5bfb6be4-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5bfb94de-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:5bfbb95a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.56']} DrugCentral uuid:5bfbe268-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:5bfc0bb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:5bfc347a-6b31-11ec-b3df-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:5bfc5d60-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5bfc86c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5bfcb04e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:5bfcd92a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5bfd0300-6b31-11ec-b3df-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5bfd2cc2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5bfd5616-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5bfd7ee8-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5bfda7c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5bfdd104-6b31-11ec-b3df-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5bfdfa12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5bfe230c-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:5bfe4be8-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5bfe7578-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:5bfe9ee0-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5bfec7bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5bfef08e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5bff1c58-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:5bff45ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.87']} DrugCentral uuid:5bff6e7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5bff978c-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mafenide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5bffc202-6b31-11ec-b3df-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:1626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 malathion targets GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.538']} DrugCentral uuid:5bffeb10-6b31-11ec-b3df-0242ac110002 UniProtKB:A2PZ98 biolink:molecularly_interacts_with DrugCentral:1626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 malathion is inhibitor of Enzyme (Acetylcholinesterase) DrugCentral uuid:5c000fa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 manidipine targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5c003d0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 manidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:5c003d0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 manidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:5c006c0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.308']} DrugCentral uuid:5c00951a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:5c00be00-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.165']} DrugCentral uuid:5c00e90c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.364']} DrugCentral uuid:5c0113dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.237']} DrugCentral uuid:5c013cd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.27']} DrugCentral uuid:5c0165c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:5c018f24-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:5c01b800-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:5c01e104-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:5c0209d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.854']} DrugCentral uuid:5c023366-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.876']} DrugCentral uuid:5c025c4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.298']} DrugCentral uuid:5c028546-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.367']} DrugCentral uuid:5c02af3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.777']} DrugCentral uuid:5c02d956-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.406']} DrugCentral uuid:5c030232-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.845']} DrugCentral uuid:5c032b18-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:5c03544e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5c037d3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:5c03a624-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.939']} DrugCentral uuid:5c03ceec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:5c03f868-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.355']} DrugCentral uuid:5c042144-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5c044a16-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:5c0472f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:5c049840-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.046']} DrugCentral uuid:5c04c112-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5c04eaa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline is blocker of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5c051478-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCF6 biolink:molecularly_interacts_with DrugCentral:1634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maprotiline is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5c053dc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:1635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maraviroc is antagonist of GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5c056694-6b31-11ec-b3df-0242ac110002 UniProtKB:P51682 biolink:molecularly_interacts_with DrugCentral:1635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maraviroc targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:5c058f66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maraviroc targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:5c05b900-6b31-11ec-b3df-0242ac110002 UniProtKB:P61813 biolink:molecularly_interacts_with DrugCentral:1635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maraviroc targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:5c05e1f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5c060ab8-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:5c063394-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:5c065f18-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5c068876-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5c06b152-6b31-11ec-b3df-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5c06da2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5c07036e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14061 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Estradiol 17-beta-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5c072c36-6b31-11ec-b3df-0242ac110002 UniProtKB:P37059 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Estradiol 17-beta-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5c0754f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P18054 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 12-lipoxygenase, 12S-type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5c077dda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15722 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets GPCR (Leukotriene B4 receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5c07a724-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5c07cfce-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5c07f8aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5c082172-6b31-11ec-b3df-0242ac110002 UniProtKB:P08170 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Seed linoleate 13S-lipoxygenase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5c084b52-6b31-11ec-b3df-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5c087410-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5c089cce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BEG3 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5c08c668-6b31-11ec-b3df-0242ac110002 UniProtKB:P48999 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5c08f30e-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5c08f30e-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5c0928ec-6b31-11ec-b3df-0242ac110002 UniProtKB:O15296 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Arachidonate 15-lipoxygenase, type II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5c0951be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q39829 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Unclassified (Lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:5c097aea-6b31-11ec-b3df-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:5c09a3a8-6b31-11ec-b3df-0242ac110002 UniProtKB:K4CF70 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Enzyme (Fatty acid hydroperoxide lyase, chloroplastic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5c09cc7a-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 masoprocol targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5c09f54c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:1638 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maxacalcitol targets Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:5c0a2152-6b31-11ec-b3df-0242ac110002 UniProtKB:P13053 biolink:molecularly_interacts_with DrugCentral:1638 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maxacalcitol is agonist of Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:5c0a4c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:5c0a7616-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5c0a9fd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5c0ac8aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.222']} DrugCentral uuid:5c0af1a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5c0b1a80-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:5c0b43ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.06']} DrugCentral uuid:5c0b6cb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5c0b9596-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:1640 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mazindol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5c0bbeea-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5c0be9a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5c0c1278-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BJF5 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole targets Kinase (Calmodulin-domain protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5c0c432e-6b31-11ec-b3df-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5c0c432e-6b31-11ec-b3df-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5c0c432e-6b31-11ec-b3df-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5c0c943c-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5c0c943c-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5c0c943c-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5c0c943c-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5c0c943c-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5c0c943c-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5c0c943c-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:1641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5c0cf92c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebhydrolin is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.119']} DrugCentral uuid:5c0d2244-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebhydrolin targets GPCR (Histamine H4 receptor) DrugCentral uuid:5c0d46ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebhydrolin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.745']} DrugCentral uuid:5c0d6fb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebhydrolin targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:5c0d98a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.161']} DrugCentral uuid:5c0dc488-6b31-11ec-b3df-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5c0df138-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5c0df138-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5c0e29e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.602']} DrugCentral uuid:5c0e29e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.602']} DrugCentral uuid:5c0e6370-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is negative allosteric modulator of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.222']} DrugCentral uuid:5c0e6370-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is negative allosteric modulator of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.222']} DrugCentral uuid:5c0e9c32-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5c0e9c32-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5c0ed4e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5c0ed4e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5c0f1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5c0f1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5c0f1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5c0f1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5c0f623e-6b31-11ec-b3df-0242ac110002 UniProtKB:P02708 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5c0f8e30-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5c0fb9fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5c0fe2cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecamylamine is blocker of Ion channel (Neuronal acetylcholine receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5c100b94-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:1648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecillinam is inhibitor of Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.035']} DrugCentral uuid:5c103524-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:1649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclozine is antagonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:5c105df6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclozine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5c108286-6b31-11ec-b3df-0242ac110002 UniProtKB:O35627 biolink:molecularly_interacts_with DrugCentral:1649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclozine is agonist of Nuclear hormone receptor (Constitutive androstane receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5c10abc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:1649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclozine targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5c10d5ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5c10fe8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5c112754-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5c115102-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5c117aa6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:5c11a38c-6b31-11ec-b3df-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5c11cc72-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:5c11f5e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:5c121eca-6b31-11ec-b3df-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5c1248e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5c1271e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.503']} DrugCentral uuid:5c129b16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5c12c3fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5c12ecba-6b31-11ec-b3df-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:5c13196a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5c13196a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meclofenamic acid targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c138832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5c146d88-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5c146d88-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5c146d88-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5c14b608-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5c14b608-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5c14b608-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5c14ff5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5c14ff5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5c14ff5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5c1547a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:5c1547a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:5c1547a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medetomidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:5c15895c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxalol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'pA2', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5c15b2d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxalol targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'pA2', 'has_quantitative_value': ['6.08']} DrugCentral uuid:5c15dbbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.561']} DrugCentral uuid:5c1604b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.88']} DrugCentral uuid:5c162d94-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5c1656ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5c167fa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.59']} DrugCentral uuid:5c16a86e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5c16d384-6b31-11ec-b3df-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5c16ff1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5c17287a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5c175156-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5c177ad2-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.45']} DrugCentral uuid:5c17a3a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.032']} DrugCentral uuid:5c17cc76-6b31-11ec-b3df-0242ac110002 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:5c17f91c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5c17f91c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medroxyprogesterone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5c182e5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1662 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 medrysone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5c1852fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:5c187c0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:5c18a5ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5c18cf22-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:5c18f7ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04828 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member C1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:5c1921c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5c194b50-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5c19744a-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5c199d3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5c19c60c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5c19ef42-6b31-11ec-b3df-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5c1a1828-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5c1a40f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:1663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefenamic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:5c1a69cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:5c1a95e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:5c1ac1f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5c1ae9a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.91']} DrugCentral uuid:5c1b143a-6b31-11ec-b3df-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:5c1b38b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5c1b6174-6b31-11ec-b3df-0242ac110002 UniProtKB:P90584 biolink:molecularly_interacts_with DrugCentral:1665 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefloquine targets Unclassified (Protein kinase Pfmrk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5c1b8a32-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5c1baf12-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.057']} DrugCentral uuid:5c1bd820-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:5c1bfcce-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5c1c25a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:5c1c4f80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 megestrol acetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.842']} DrugCentral uuid:5c1c7bc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:1670 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meglutol targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:5c1ca552-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5c1cce4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.56']} DrugCentral uuid:5c1cf7d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5c1d213a-6b31-11ec-b3df-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5c1d4b06-6b31-11ec-b3df-0242ac110002 UniProtKB:P35398 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Nuclear hormone receptor (Nuclear receptor ROR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5c1d74f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5c1d9e12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5c1dc6f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:5c1df006-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5c1e213e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:5c1e213e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:5c1e213e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51050 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Melatonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:5c1e6252-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5c1e8b42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melatonin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5c1eb41e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5c1edd86-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5c1f0676-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5c1f2f5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5c1f5860-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meloxicam targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:5c1f813c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:5c1faa18-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5c1fd2ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:5c1ff892-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:5c2021dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.717']} DrugCentral uuid:5c204acc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:5c207394-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5c209d06-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.063']} DrugCentral uuid:5c20c5d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.237']} DrugCentral uuid:5c20eea0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5c211772-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.357']} DrugCentral uuid:5c214198-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.469']} DrugCentral uuid:5c216a7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets Enzyme (Cytochrome P450 2D6) DrugCentral uuid:5c218efa-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.387']} DrugCentral uuid:5c21b7e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63016 biolink:molecularly_interacts_with DrugCentral:1678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 melphalan targets Transporter (L-type amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:5c21e1ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine targets Ion channel (5-hydroxytryptamine receptor 3A) DrugCentral uuid:5c220664-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:5c222b1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05586 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5c2253e4-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5c227d4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00961 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5c22aa4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5c22aa4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5c22e340-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:5c22e340-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 memantine is negative allosteric modulator of Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:5c23190a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5c2341dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5c236acc-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5c2393b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5c23bda6-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5c23e7ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P30305 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (M-phase inducer phosphatase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5c241094-6b31-11ec-b3df-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:5c243948-6b31-11ec-b3df-0242ac110002 UniProtKB:P30307 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Dual specificity phosphatase Cdc25C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:5c2462a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P15374 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Ubiquitin carboxyl-terminal hydrolase isozyme L3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:5c248b8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Dual specificity phosphatase Cdc25A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5c24b45e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q64346 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Dual specificity protein phosphatase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:5c24ddb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28563 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Dual specificity protein phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:5c25077e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (M-phase inducer phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5c25305a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5c25592c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:1684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menadione sodium bisulfite targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:5c25830c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1685 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 menatetrenone targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:5c25abd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.263']} DrugCentral uuid:5c25d4ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.119']} DrugCentral uuid:5c25fdaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:5c262730-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.959']} DrugCentral uuid:5c26502a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.485']} DrugCentral uuid:5c26792e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:5c26a214-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.069']} DrugCentral uuid:5c26cb4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.742']} DrugCentral uuid:5c26f43a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.167']} DrugCentral uuid:5c271d0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.504']} DrugCentral uuid:5c2745f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:5c277108-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:5c2799e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:5c27c2ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:5c27ec64-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:5c281540-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:5c283e30-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:5c286798-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.411']} DrugCentral uuid:5c2890e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:5c28b9aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:5c28e268-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UDY8 biolink:molecularly_interacts_with DrugCentral:1688 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pecazine targets Enzyme (Mucosa-associated lymphoid tissue lymphoma translocation protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5c290c2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepenzolate is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5c293222-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepenzolate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:5c295b12-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepenzolate is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:5c298402-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepenzolate targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5c29acf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:5c29d6aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5c29ff72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:5c2a23e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.625']} DrugCentral uuid:5c2a4d24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:5c2a7218-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:5c2a9c02-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5c2ac4e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:5c2aedce-6b31-11ec-b3df-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:5c2b26e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5c2b26e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5c2b26e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5c2b26e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5c2b83b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c2b83b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c2b83b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c2b83b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c2bd0c2-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pethidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:5c2bf994-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephentermine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5c2c4106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5c2c4106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5c2c4106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5c2c4106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5c2c4106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5c2c4106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5c2c4106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5c2c4106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5c2c4106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5c2c4106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mephenytoin is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5c2cccc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5c2cccc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5c2cccc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5c2d060e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5c2d2aa8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:5c2d4f4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:5c2d7454-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:5c2d98e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:5c2dbd88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:5c2de218-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1700 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepivacaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:5c2e073e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprednisone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5c2e2bf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.821']} DrugCentral uuid:5c2e5cf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5c2e5cf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5c2e5cf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) DrugCentral uuid:5c2e9fa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5c2e9fa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5c2e9fa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) DrugCentral uuid:5c2ee1d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5c2ee1d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5c2ee1d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) DrugCentral uuid:5c2f245c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5c2f245c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5c2f245c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprobamate is agonist of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5c2f5ea4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:1705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meproscillarin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:5c2f844c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:5c2fad0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:5c2fd640-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5c2fff26-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:5c3027f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meptazinol is partial agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.06']} DrugCentral uuid:5c3050c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.237']} DrugCentral uuid:5c307b4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.252']} DrugCentral uuid:5c30a430-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:5c30cd0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.276']} DrugCentral uuid:5c30f5de-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.955']} DrugCentral uuid:5c311f14-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:5c3147e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5c3170a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5c31998a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q389T8 biolink:molecularly_interacts_with DrugCentral:1707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequitazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:5c31c2c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.789']} DrugCentral uuid:5c31ebb0-6b31-11ec-b3df-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:5c32102c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:5c32349e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Enzyme (Purine nucleoside phosphorylase) DrugCentral uuid:5c325bc2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06203 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine is inhibitor of Enzyme (Amidophosphoribosyltransferase) DrugCentral uuid:5c328214-6b31-11ec-b3df-0242ac110002 UniProtKB:P51580 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Enzyme (Thiopurine S-methyltransferase) DrugCentral uuid:5c32a6b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WP01 biolink:molecularly_interacts_with DrugCentral:1708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mercaptopurine targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5c32cf76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X6V3 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Penicillin-binding protein 2) DrugCentral uuid:5c32f456-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5D1E9 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Penicillin-binding protein 4) DrugCentral uuid:5c3318d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X6V7 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (D-ala-D-ala-carboxypeptidase; D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase family protein; Penicillin-binding protein 5) DrugCentral uuid:5c333d44-6b31-11ec-b3df-0242ac110002 UniProtKB:A1KS91 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Penicillin-binding protein 1) DrugCentral uuid:5c3361ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7CHG0 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6) DrugCentral uuid:5c338696-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem is inhibitor of Enzyme (D-alanyl-D-alanine carboxypeptidase DacB) DrugCentral uuid:5c33ac02-6b31-11ec-b3df-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5c33d4a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9K2N0 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Unclassified (Beta-lactamase class B VIM-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5c33fd7e-6b31-11ec-b3df-0242ac110002 UniProtKB:C7C422 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Beta-lactamase NDM-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5c342862-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XEC0 biolink:molecularly_interacts_with DrugCentral:1709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meropenem targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5c345242-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5c347b00-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:5c349fa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:5c34c52e-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) DrugCentral uuid:5c34e9c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5c3512c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5c353cde-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5c356614-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WU19 biolink:molecularly_interacts_with DrugCentral:1710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesalazine targets Enzyme (Hydroxyacid oxidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5c358ee6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:5c35b7d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.724']} DrugCentral uuid:5c35e0c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5c360d08-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:5c36392c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.125']} DrugCentral uuid:5c3661fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.804']} DrugCentral uuid:5c368b34-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5c36b3fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:5c36dce2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.744']} DrugCentral uuid:5c3705b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5c372ef4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:5c3757c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.046']} DrugCentral uuid:5c3780a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:5c37a96a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:5c37d5ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesoridazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.041']} DrugCentral uuid:5c3800ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.647']} DrugCentral uuid:5c3829da-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:5c3852c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:5c387c3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.282']} DrugCentral uuid:5c38a522-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.147']} DrugCentral uuid:5c38cdf4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestranol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.958']} DrugCentral uuid:5c38f6ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orciprenaline is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c392024-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:1720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orciprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5c39490a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1721 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metaraminol is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5c396d90-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.562']} DrugCentral uuid:5c3997d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:5c39c3c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:5c39ed56-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.658']} DrugCentral uuid:5c3a1632-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.504']} DrugCentral uuid:5c3a3f7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5c3a6858-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:5c3a9152-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5c3aba24-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5c3ae3fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5c3b0cc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5c3b35a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5c3b5e84-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.124']} DrugCentral uuid:5c3b8a12-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.583']} DrugCentral uuid:5c3bb2f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.319']} DrugCentral uuid:5c3bdcd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.018']} DrugCentral uuid:5c3c05dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5c3c48bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:5c3c721a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:5c3c9b00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:5c3cc440-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5c3ced26-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5c3d1616-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.872']} DrugCentral uuid:5c3d3efc-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5c3d6904-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5c3d91fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5c3dbada-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.867']} DrugCentral uuid:5c3de42e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.839']} DrugCentral uuid:5c3e0d14-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5c3e35fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5c3e5ec2-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5c3e88b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5c3eb188-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5c3eda82-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5c3f0eee-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c3f0eee-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c3f0eee-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c3f0eee-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c3f683a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5c3f683a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5c3f683a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metergoline targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5c3faa5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y478 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Kinase (5'-AMP-activated protein kinase subunit beta-1) DrugCentral uuid:5c3fcf64-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5c3ff836-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.697']} DrugCentral uuid:5c4020fe-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.401']} DrugCentral uuid:5c4049c6-6b31-11ec-b3df-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['2.499']} DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c413246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M9 biolink:molecularly_interacts_with DrugCentral:1725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metformin is inhibitor of Enzyme (Mitochondrial complex I (NADH dehydrogenase)) DrugCentral uuid:5c4353e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:5c437e48-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:5c43a72e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine is agonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:5c43cbbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5c43f4ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:5c441ee8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5c444904-6b31-11ec-b3df-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5c4471e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:1726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methacholine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5c449bfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P43351 biolink:molecularly_interacts_with DrugCentral:1727 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metacycline targets Nuclear other (DNA repair protein RAD52 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5c44c708-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.78']} DrugCentral uuid:5c44f002-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:5c4518ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5c45423c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:5c4566ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZZ6 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets Ion channel (Neuronal acetylcholine receptor subunit alpha-10) DrugCentral uuid:5c458b3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5c45bf64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:5c45bf64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:5c45bf64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:5c45bf64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:5c460c8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylmethadol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5c463566-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetylmethadol is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:5c4659ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.383']} DrugCentral uuid:5c468552-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5c46ae38-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.133']} DrugCentral uuid:5c46d71e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:5c46fffa-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5c47299e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:5c475270-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:5c477b74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.611']} DrugCentral uuid:5c47a4c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5c47ce80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01827 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:5c47f77a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5c482042-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.88']} DrugCentral uuid:5c484a7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:1732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methamphetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5c488294-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:5c488294-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:5c488294-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:5c488294-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:5c488294-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1736 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methanthelinium is antagonist of GPCR (Muscarinic acetylcholine receptor) DrugCentral uuid:5c48d10e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5c48fa76-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:5c492348-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:5c494c38-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.745']} DrugCentral uuid:5c4975f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:5c499ed6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.409']} DrugCentral uuid:5c49c7ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.843']} DrugCentral uuid:5c49f0ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5c4a1b2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:5c4a4624-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.939']} DrugCentral uuid:5c4a6f14-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.228']} DrugCentral uuid:5c4a97fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:5c4ac18a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5c4aea66-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methapyrilene targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:5c4b1aea-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:5c4b1aea-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:5c4b1aea-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:5c4b64f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:5c4b64f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:5c4b64f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:5c4bad2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5c4bad2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5c4bad2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5c4bf780-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:5c4bf780-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:5c4bf780-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:5c4c44ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:5c4c44ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:5c4c44ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:5c4c8e16-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:5c4c8e16-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:5c4c8e16-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:5c4cd678-6b31-11ec-b3df-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is agonist of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3.91']} DrugCentral uuid:5c4cd678-6b31-11ec-b3df-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is agonist of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3.91']} DrugCentral uuid:5c4cd678-6b31-11ec-b3df-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is agonist of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3.91']} DrugCentral uuid:5c4d1afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:5c4d1afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:5c4d57ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5c4d57ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5c4d57ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-2/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5c4da134-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5c4da134-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5c4da134-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1739 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methaqualone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4e1d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metharbital is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c4edf4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5c4f08b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5c4f31c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5c4f5a9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:5c4f836e-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:5c4fad6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5c4fd63e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5c4fff9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide is inhibitor of Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:5c5029fe-6b31-11ec-b3df-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5c50537a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:5c507c60-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5c50a546-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:5c50ce86-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5c50f762-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:5c51203e-6b31-11ec-b3df-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5c514924-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5c51739a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5c519c80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5c51c548-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5c51ee24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5c521778-6b31-11ec-b3df-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5c524072-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:5c526944-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:5c529248-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:5c52bbc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5c52e4b4-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5c530d9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:5c533676-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5c5360d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5c53b344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c53b344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c53b344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c53b344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c53b344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c53b344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c53b344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c53b344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c53b344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c53b344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c53b344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c53b344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5c5465e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5c5465e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5c549b60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5c54c450-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.58']} DrugCentral uuid:5c54ed40-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:1741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methazolamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:5c551766-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methdilazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5c553c6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07944 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin targets Enzyme (Beta-lactam-inducible penicillin-binding protein) DrugCentral uuid:5c5560e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18843 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin targets Enzyme (NH(3)-dependent NAD(+) synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:5c5598da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5c5598da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5c5598da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5c5598da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5c5598da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meticillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5c55e7ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P07202 biolink:molecularly_interacts_with DrugCentral:1745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamazole is inhibitor of Enzyme (Thyroid peroxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5c5610da-6b31-11ec-b3df-0242ac110002 UniProtKB:P80025 biolink:molecularly_interacts_with DrugCentral:1745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamazole targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5c5639ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P22079 biolink:molecularly_interacts_with DrugCentral:1745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamazole targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:5c566332-6b31-11ec-b3df-0242ac110002 UniProtKB:P15101 biolink:molecularly_interacts_with DrugCentral:1745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamazole targets Enzyme (Dopamine beta-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:5c568c18-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1747 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methocarbamol is inhibitor of Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5c56b4f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital targets Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:5c56e140-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5c56e140-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5c56e140-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5c572100-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:5c572100-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1748 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methohexital targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) DrugCentral uuid:5c574fe0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5c577448-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:5c57991e-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:5c57bd86-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:5c57e20c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5c580ae8-6b31-11ec-b3df-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:5c583072-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Folylpolyglutamate synthase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5c585926-6b31-11ec-b3df-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:5c587dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5c58a674-6b31-11ec-b3df-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5c58d158-6b31-11ec-b3df-0242ac110002 UniProtKB:P14207 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Membrane receptor (Folate receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:5c58fa34-6b31-11ec-b3df-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:5c5922e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5c594d04-6b31-11ec-b3df-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5c597658-6b31-11ec-b3df-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.14']} DrugCentral uuid:5c599f3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5c59c7fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:5c59f16e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07382 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.89']} DrugCentral uuid:5c5a1a68-6b31-11ec-b3df-0242ac110002 UniProtKB:P00378 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5c5a4344-6b31-11ec-b3df-0242ac110002 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5c5a6c20-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.68']} DrugCentral uuid:5c5a9664-6b31-11ec-b3df-0242ac110002 UniProtKB:C3SWJ7 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5c5ac08a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:5c5aea60-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A017 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5c5b1346-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WNX1 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.08']} DrugCentral uuid:5c5b3c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q81R22 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.91']} DrugCentral uuid:5c5b6508-6b31-11ec-b3df-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:5c5b8de4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00380 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5c5bb6b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5c5be032-6b31-11ec-b3df-0242ac110002 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:5c5c0922-6b31-11ec-b3df-0242ac110002 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:5c5c3294-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:1751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methotrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:5c5c5bac-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomepromazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.237']} DrugCentral uuid:5c5c8604-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:1752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomepromazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5c5caee0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5c5cd794-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5c5d00e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:5c5d29b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5c5d5a48-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5c5d5a48-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5c5d5a48-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1753 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5c5d9bb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is agonist of Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5df8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:1754 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxyflurane is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5c5ec126-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:5c5eea66-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:5c5f1356-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:5c5f3c32-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.01']} DrugCentral uuid:5c5f6518-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:5c5f8e9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:1757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methscopolamine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:5c5fbf2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methsuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:5c5fbf2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methsuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:5c5fbf2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methsuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:5c5ff8a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylclothiazide is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:5c601f26-6b31-11ec-b3df-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:1761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metildigoxin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:5c604406-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa is agonist of GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:5c606878-6b31-11ec-b3df-0242ac110002 UniProtKB:P20711 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Enzyme (Aromatic-L-amino-acid decarboxylase) DrugCentral uuid:5c608cfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.282']} DrugCentral uuid:5c60b62a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.286']} DrugCentral uuid:5c60df06-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.672']} DrugCentral uuid:5c6107c4-6b31-11ec-b3df-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:1762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopa targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5c6130a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5c6159d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:5c61829e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5c61ac4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Thioredoxin reductase 1, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:5c61d528-6b31-11ec-b3df-0242ac110002 UniProtKB:O15770 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Glutathione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5c620110-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:5c622a32-6b31-11ec-b3df-0242ac110002 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5c625322-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:1763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylthioninium chloride targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5c627d0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.268']} DrugCentral uuid:5c62a5e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.559']} DrugCentral uuid:5c62cece-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.225']} DrugCentral uuid:5c62f7a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.633']} DrugCentral uuid:5c6320e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5c6349d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is partial agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5c6372b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5c639b88-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.928']} DrugCentral uuid:5c63c5cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.678']} DrugCentral uuid:5c63ee9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.244']} DrugCentral uuid:5c64177a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5c64402e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5c6469c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5c6492b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.033']} DrugCentral uuid:5c64bb94-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.39']} DrugCentral uuid:5c64e57e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5c650edc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1764 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylergometrine is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5c6537cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:5c6560b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5c658a2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.93']} DrugCentral uuid:5c65b698-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.99']} DrugCentral uuid:5c65df88-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5c66085a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.34']} DrugCentral uuid:5c6631c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.58']} DrugCentral uuid:5c665a9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:5c668384-6b31-11ec-b3df-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:5c66ac4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:5c66d582-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:5c66fe68-6b31-11ec-b3df-0242ac110002 UniProtKB:P09483 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:5c672726-6b31-11ec-b3df-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.97']} DrugCentral uuid:5c675002-6b31-11ec-b3df-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:5c678586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:5c678586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:5c678586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:5c678586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:5c67d5e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:5c67d5e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1765 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naltrexone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:5c680b64-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5c68345e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5c685d30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5c688616-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:5c68afec-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:5c68d8d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1766 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylparaben targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5c6901ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.252']} DrugCentral uuid:5c692a80-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5c695622-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5c698002-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.615']} DrugCentral uuid:5c69a8d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:5c69d282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5c69fb72-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylphenidate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.08']} DrugCentral uuid:5c6a244e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1768 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5c6a4d0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:1768 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone targets Cytosolic other (Annexin A1) DrugCentral uuid:5c6a720a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1768 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:5c6a9b04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:1768 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone is activator of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5c6ac3d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5c6ae870-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1771 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylprednisolone succinate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5c6b1656-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyprylon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5c6b1656-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyprylon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5c6b1656-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:1774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyprylon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) DrugCentral uuid:5c6b527e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.326']} DrugCentral uuid:5c6b7b5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5c6ba4cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.214']} DrugCentral uuid:5c6bcdb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:5c6bf67a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.509']} DrugCentral uuid:5c6c1f60-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5c6c48a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5c6c717c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.663']} DrugCentral uuid:5c6c9a4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:5c6cc320-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:5c6ced00-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:5c6d15be-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.213']} DrugCentral uuid:5c6d3e86-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.334']} DrugCentral uuid:5c6d6870-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5c6d91e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:5c6dbabe-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.054']} DrugCentral uuid:5c6de390-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5c6e0c58-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5c6e35d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5c6e5ed8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07820 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Cytosolic other (Induced myeloid leukemia cell differentiation protein Mcl-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:5c6e8886-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07817 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Cytosolic other (Bcl-2-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:5c6eb1da-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.967']} DrugCentral uuid:5c6edb1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:5c6f03c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5c6f2cb4-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5c6f55e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5c6f7ed0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5c6fa784-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:5c6fd7ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:5c6fd7ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:5c6fd7ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:5c70196c-6b31-11ec-b3df-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:5c70422a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35364 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5c706b1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5c7094f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5c70bdb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.45']} DrugCentral uuid:5c70e6c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.34']} DrugCentral uuid:5c710fca-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methysergide is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.34']} DrugCentral uuid:5c713a22-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metiazinic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5c716308-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metipranolol is antagonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:5c7187a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1779 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metipranolol is antagonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:5c71ad72-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metixene is antagonist of GPCR (5-hydroxytryptamine receptor 2C) DrugCentral uuid:5c71d2a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metixene is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5c71f71e-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metixene targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5c721fe6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metochalcone targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5c7248c2-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5c727266-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:5c729b42-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:5c72c41e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.979']} DrugCentral uuid:5c72ed04-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.397']} DrugCentral uuid:5c731630-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.904']} DrugCentral uuid:5c733ef8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5c7367de-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5c738c64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.509']} DrugCentral uuid:5c73b608-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:5c73ded0-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5c7407ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5c74316e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5c745acc-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:5c74838a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:5c74ac8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5c74d5c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:5c74feaa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5c752786-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5c75553a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5c75553a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5c759a22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5c759a22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5c759a22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5c759a22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5c759a22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5c75fe36-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5c75fe36-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5c75fe36-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5c75fe36-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5c76535e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5c76535e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5c76535e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5c769bd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:5c769bd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:5c769bd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:5c76e512-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:5c76e512-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:5c76e512-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:5c772b12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5c772b12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5c7760b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P97288 biolink:molecularly_interacts_with DrugCentral:1782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoclopramide is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5c7789ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:1783 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metolazone targets Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.45']} DrugCentral uuid:5c77b294-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:1783 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metolazone is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:5c77d828-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1783 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metolazone targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:5c78056e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metopimazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:5c78307a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metopimazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:5c785992-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metopimazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:5c7882e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5c78abc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c78d49e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5c78fd8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.79']} DrugCentral uuid:5c7926ce-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.83']} DrugCentral uuid:5c795752-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c795752-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c795752-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c799816-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:5c79c200-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:1786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metoprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:5c79eae6-6b31-11ec-b3df-0242ac110002 UniProtKB:C4LW95 biolink:molecularly_interacts_with DrugCentral:1790 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metronidazole targets Enzyme (Thioredoxin reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5c7a1458-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:5c7a3d5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:5c7a66ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P15150 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone targets Enzyme (Cytochrome P450 11B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5c7a8fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:P15393 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5c7ab89a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1791 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metyrapone is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.84']} DrugCentral uuid:5c7ae16c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07101 biolink:molecularly_interacts_with DrugCentral:1792 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metirosine is inhibitor of Enzyme (Tyrosine 3-monooxygenase) DrugCentral uuid:5c7b067e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5c7b2f3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:5c7b53c2-6b31-11ec-b3df-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:5c7b7834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:5c7b9eea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:5c7bc366-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5c7bed32-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:5c7c160e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5c7c3f9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5c7c6870-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:5c7c9160-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5c7cbaaa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:5c7ce390-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:5c7d0c62-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.51']} DrugCentral uuid:5c7d352a-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:5c7d5f50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:5c7d8ab6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62205 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5c7db388-6b31-11ec-b3df-0242ac110002 UniProtKB:A2APX8 biolink:molecularly_interacts_with DrugCentral:1794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mexiletine targets Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5c7ddc50-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5c7e0590-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5c7e2e58-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5c7e5748-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5c7e7fe8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5c7ea4d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:5c7ecdae-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5c7ef694-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5c7f1f52-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5c7f4ab8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5c7f7376-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5c7f9c34-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:5c7fc4fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5c7fef0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:5c8017f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5c8040da-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:5c806a1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5c809364-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5c80bc2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5c80e508-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.33']} DrugCentral uuid:5c810f7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5c81385a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5c816122-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:5c8189ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P02768 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Secreted (Serum albumin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.18']} DrugCentral uuid:5c81b316-6b31-11ec-b3df-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5c81dbd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14778 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Membrane receptor (Interleukin-1 receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5c820474-6b31-11ec-b3df-0242ac110002 UniProtKB:P41222 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c8244de-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5c8244de-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5c8244de-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5c8244de-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5c8244de-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5c8244de-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5c8244de-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:1795 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mezlocillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5c82a78a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5c82d08e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5c82fa50-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.319']} DrugCentral uuid:5c83230e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:5c834bea-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.149']} DrugCentral uuid:5c837520-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:5c83a02c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:5c83c8fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:5c83f202-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5c841b74-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.175']} DrugCentral uuid:5c844450-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:5c846d36-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5c849608-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.569']} DrugCentral uuid:5c84c0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5c84e98c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.245']} DrugCentral uuid:5c851272-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.003']} DrugCentral uuid:5c853b30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.125']} DrugCentral uuid:5c856452-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.465']} DrugCentral uuid:5c858d2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:5c85b60a-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.526']} DrugCentral uuid:5c85dee6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.541']} DrugCentral uuid:5c8608da-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.638']} DrugCentral uuid:5c8631c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:5c865a9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:5c868490-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5c86aefc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.027']} DrugCentral uuid:5c86d7ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5c8700aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5c8729ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5c8752da-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5c877b98-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.06']} DrugCentral uuid:5c87a58c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:5c87cefe-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5c87f7ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:5c8820a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:5c884a0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:5c88746c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5c889d3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5c88c62e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:5c88ef0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5c891836-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5c89411c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5c8969ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5c89a792-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:5c89dac8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5c8a03ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5c8a2da2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5c8a584a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5c8a8518-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5c8a8518-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5c8ac712-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5c8ac712-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5c8ac712-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5c8ac712-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5c8b1b7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5c8b1b7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5c8b1b7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5c8b65be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5c8b65be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5c8b65be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5c8baa74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5c8baa74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5c8be700-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:5c8be700-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:5c8be700-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:5c8c2df0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5c8c2df0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5c8c62d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NG02 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin targets GPCR (G-protein coupled receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:5c8c8bc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:1796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mianserin is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5c8cb50e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c8cdde0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5c8d06c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5c8d2fa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5c8d5c0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c8d84de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5c8dadc4-6b31-11ec-b3df-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5c8dd7ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5c8e00bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5c8e2970-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:5c8e5256-6b31-11ec-b3df-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c8e7b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5c8ea666-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5c8ecf2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5c8ef800-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5c8f217c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07652 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is gating inhibitor of Ion channel (Voltage-dependent R-type calcium channel subunit alpha-1E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5c8f4a58-6b31-11ec-b3df-0242ac110002 UniProtKB:P54282 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is gating inhibitor of Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5c8f7334-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96D31 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Calcium release-activated calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5c8f9c24-6b31-11ec-b3df-0242ac110002 UniProtKB:P15390 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5c8fc80c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5c8ff232-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mibefradil is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.602']} DrugCentral uuid:5c901ae6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AIC4 biolink:molecularly_interacts_with DrugCentral:1798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 micafungin targets Unclassified (Beta-1,3-glucan synthase) DrugCentral uuid:5c9040d4-6b31-11ec-b3df-0242ac110002 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:1798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 micafungin is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) DrugCentral uuid:5c9065b4-6b31-11ec-b3df-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.715']} DrugCentral uuid:5c908e86-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.137']} DrugCentral uuid:5c90b758-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.588']} DrugCentral uuid:5c90e0b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:5c91097e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.609']} DrugCentral uuid:5c91326e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.505']} DrugCentral uuid:5c915b54-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5c9184e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.097']} DrugCentral uuid:5c91adac-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.828']} DrugCentral uuid:5c91d6a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:5c91fb40-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5c92249e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:5c924d84-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.535']} DrugCentral uuid:5c927660-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.183']} DrugCentral uuid:5c92a054-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.952']} DrugCentral uuid:5c92ca16-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.452']} DrugCentral uuid:5c92f310-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.555']} DrugCentral uuid:5c931be2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.296']} DrugCentral uuid:5c9344f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.785']} DrugCentral uuid:5c936ee4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.964']} DrugCentral uuid:5c9397b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.178']} DrugCentral uuid:5c93c092-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:5c93e982-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.812']} DrugCentral uuid:5c94134e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.175']} DrugCentral uuid:5c943cc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.351']} DrugCentral uuid:5c9465b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.386']} DrugCentral uuid:5c948f5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.869']} DrugCentral uuid:5c94b876-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5c94e148-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.136']} DrugCentral uuid:5c950a1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.799']} DrugCentral uuid:5c953490-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.271']} DrugCentral uuid:5c955d6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.825']} DrugCentral uuid:5c958648-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:5c95af4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:5c95d468-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.923']} DrugCentral uuid:5c95fd44-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5c96260c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.729']} DrugCentral uuid:5c964ede-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5c9677f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5c96a0c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.534']} DrugCentral uuid:5c96ca94-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5c96f37a-6b31-11ec-b3df-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:5c97211a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:5c974b40-6b31-11ec-b3df-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:5c9773fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.381']} DrugCentral uuid:5c979d8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.562']} DrugCentral uuid:5c97c64c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.58']} DrugCentral uuid:5c97ef28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5c9817f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5c984144-6b31-11ec-b3df-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.109']} DrugCentral uuid:5c9869f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.792']} DrugCentral uuid:5c9892de-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.326']} DrugCentral uuid:5c98bba6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.029']} DrugCentral uuid:5c98e720-6b31-11ec-b3df-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.922']} DrugCentral uuid:5c991024-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.674']} DrugCentral uuid:5c993900-6b31-11ec-b3df-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.792']} DrugCentral uuid:5c9961dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.692']} DrugCentral uuid:5c998b26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.711']} DrugCentral uuid:5c99b3e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:5c99dcd4-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:5c9a0632-6b31-11ec-b3df-0242ac110002 UniProtKB:P22443 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5c9a2f4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5c9a57fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5c9a80da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5c9aab64-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPP7 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Mycocyclosin synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:5c9ad558-6b31-11ec-b3df-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5c9afe48-6b31-11ec-b3df-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:5c9b274c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96D31 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Ion channel (Calcium release-activated calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5c9b5082-6b31-11ec-b3df-0242ac110002 UniProtKB:K4CF70 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (Fatty acid hydroperoxide lyase, chloroplastic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5c9b795e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:1800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miconazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5c9ba23a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['6']} DrugCentral uuid:5c9bcb16-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.353']} DrugCentral uuid:5c9bf44c-6b31-11ec-b3df-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9c1d3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is antagonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5c9c4dca-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:5c9c4dca-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:5c9c4dca-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:5c9c99b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:5c9c99b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:5c9c99b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:5c9ce2a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:5c9ce2a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:5c9ce2a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9d5c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5c9e4288-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.444']} DrugCentral uuid:5c9e4288-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.444']} DrugCentral uuid:5c9e4288-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.444']} DrugCentral uuid:5c9e8ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.613']} DrugCentral uuid:5c9e8ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.613']} DrugCentral uuid:5c9e8ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.613']} DrugCentral uuid:5c9ed73e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5c9ed73e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5c9ed73e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5c9f2040-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:5c9f2040-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:5c9f2040-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.125']} DrugCentral uuid:5c9f68ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5c9f68ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5c9f68ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:1802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5c9fab3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midodrine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5c9fcfcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:1803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midodrine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:5c9ff894-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.001']} DrugCentral uuid:5ca02260-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.957']} DrugCentral uuid:5ca04d1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5ca075f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.918']} DrugCentral uuid:5ca09f92-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone is antagonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5ca0c8dc-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5ca0f1c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.095']} DrugCentral uuid:5ca11b66-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5ca1444c-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5ca16d96-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:5ca1967c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone is antagonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5ca1c098-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5ca1e974-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:5ca21584-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.081']} DrugCentral uuid:5ca24072-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.255']} DrugCentral uuid:5ca26944-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.256']} DrugCentral uuid:5ca292de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.374']} DrugCentral uuid:5ca2bbce-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5ca2e48c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63449 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.46']} DrugCentral uuid:5ca30d5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21447 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Transporter (P-glycoprotein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5ca33694-6b31-11ec-b3df-0242ac110002 UniProtKB:F1Q298 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5ca35f66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N1U3 biolink:molecularly_interacts_with DrugCentral:1805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifepristone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5ca3891e-6b31-11ec-b3df-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol is inhibitor of Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5ca3b1dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04746 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Pancreatic alpha-amylase) DrugCentral uuid:5ca3d856-6b31-11ec-b3df-0242ac110002 UniProtKB:P04062 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:5ca40394-6b31-11ec-b3df-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol is inhibitor of Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5ca42c70-6b31-11ec-b3df-0242ac110002 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5ca45542-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:5ca47f2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35574 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5ca4a7fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5ca4d0bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P09848 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Lactase-phlorizin hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5ca4f984-6b31-11ec-b3df-0242ac110002 UniProtKB:Q58D55 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:5ca522c4-6b31-11ec-b3df-0242ac110002 UniProtKB:C0HJB3 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Alpha-mannosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:5ca54b96-6b31-11ec-b3df-0242ac110002 UniProtKB:P56526 biolink:molecularly_interacts_with DrugCentral:1806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglitol targets Enzyme (Alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ca57472-6b31-11ec-b3df-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5ca59d4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16739 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat is inhibitor of Enzyme (Ceramide glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5ca5c832-6b31-11ec-b3df-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5ca5f0f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5ca619cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q69ZF3 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Non-lysosomal glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5ca6430c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5ca66bc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCG7 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Non-lysosomal glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5ca6950a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5ca6bde6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35573 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5ca6e744-6b31-11ec-b3df-0242ac110002 UniProtKB:P70699 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5ca71020-6b31-11ec-b3df-0242ac110002 UniProtKB:B5THE3 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Sucrase-isomaltase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5ca738de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9LGC6 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Putative alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5ca76192-6b31-11ec-b3df-0242ac110002 UniProtKB:O70282 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Trehalase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5ca78d16-6b31-11ec-b3df-0242ac110002 UniProtKB:I3LIR5 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5ca7ba16-6b31-11ec-b3df-0242ac110002 UniProtKB:O88693 biolink:molecularly_interacts_with DrugCentral:1807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miglustat targets Enzyme (Ceramide glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5ca7e52c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Ion channel (Glutamate receptor ionotropic, NMDA 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5ca80e08-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:5ca83766-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5ca86038-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5ca88a2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:5ca8b394-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:5ca8dc66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milnacipran targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5ca9054c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5ca92e0a-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:5ca958f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5ca98404-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XSW7 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Cyclic nucleotide phosphodiesterase PDE3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5ca9acd6-6b31-11ec-b3df-0242ac110002 UniProtKB:O77823 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Cyclic AMP-specific phosphodiesterase SSPDE4A1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5ca9d58a-6b31-11ec-b3df-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5ca9fec0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28156 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5caa2792-6b31-11ec-b3df-0242ac110002 UniProtKB:O89085 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5caa544c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5caa544c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5caa94e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5caa94e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5caa94e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5caa94e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:1809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 milrinone targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5caae1aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:1810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miltefosine targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5cab0a68-6b31-11ec-b3df-0242ac110002 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:1810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 miltefosine targets Enzyme (Dual specificity phosphatase Cdc25A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5cab35c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P34896 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Serine hydroxymethyltransferase, cytosolic) DrugCentral uuid:5cab5b3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5cab840c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08543 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Ribonucleoside-diphosphate reductase large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:5cabacc0-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5cabd600-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:1811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mimosine targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5cabfec8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minaprine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5cac27ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minaprine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:5cac508a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minaprine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5cac79d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:1812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minaprine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:5caca29c-6b31-11ec-b3df-0242ac110002 UniProtKB:P02980 biolink:molecularly_interacts_with DrugCentral:1813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minocycline targets Transporter (Tetracycline resistance protein, class B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.638']} DrugCentral uuid:5caccb64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z7H2 biolink:molecularly_interacts_with DrugCentral:1813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minocycline targets Unclassified (30S ribosomal protein S4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ka', 'has_quantitative_value': ['6']} DrugCentral uuid:5cacf616-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z8T8 biolink:molecularly_interacts_with DrugCentral:1813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minocycline targets Unclassified (30S ribosomal protein S9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ka', 'has_quantitative_value': ['5.756']} DrugCentral uuid:5cad1ef2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48048 biolink:molecularly_interacts_with DrugCentral:1814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minoxidil targets Ion channel (ATP-sensitive inward rectifier potassium channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:5cad4bb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minoxidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) DrugCentral uuid:5cad4bb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minoxidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) DrugCentral uuid:5cad7a96-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5cada3e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:5cadccd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5cadf5ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:5cae1e9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5cae47dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:5cae70e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:5cae99bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:5caec298-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:5caef0e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:5caf1a2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5caf42fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:5caf6d4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5caf91b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:5cafb644-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5cafdf20-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5cb0084c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.84']} DrugCentral uuid:5cb0313c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5cb05a18-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5cb082e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5cb0ae00-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5cb0de84-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5cb0de84-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5cb0de84-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirtazapine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5cb11f48-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:1817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 misoprostol is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5cb148b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:1817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 misoprostol is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5cb171b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:1817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 misoprostol is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5cb19a9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:1817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 misoprostol targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.028']} DrugCentral uuid:5cb1c75e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitiglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5cb1c75e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitiglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5cb1fc88-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:1819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitomycin targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5cb22578-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:5cb24e5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:5cb278e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:5cb2a1e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.512']} DrugCentral uuid:5cb2cad2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.186']} DrugCentral uuid:5cb2f3ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5cb31d0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.376']} DrugCentral uuid:5cb3476e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) DrugCentral uuid:5cb36bea-6b31-11ec-b3df-0242ac110002 UniProtKB:P10109 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane targets Unclassified (Adrenodoxin, mitochondrial) DrugCentral uuid:5cb39084-6b31-11ec-b3df-0242ac110002 UniProtKB:P05108 biolink:molecularly_interacts_with DrugCentral:1820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitotane is inhibitor of Enzyme (Cholesterol side-chain cleavage enzyme, mitochondrial) DrugCentral uuid:5cb3b55a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.532']} DrugCentral uuid:5cb3deb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.841']} DrugCentral uuid:5cb40776-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.306']} DrugCentral uuid:5cb4303e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.729']} DrugCentral uuid:5cb45abe-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.744']} DrugCentral uuid:5cb483c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.108']} DrugCentral uuid:5cb4aca8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.047']} DrugCentral uuid:5cb4d570-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:5cb4fa64-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone is inhibitor of Enzyme (DNA topoisomerase 2-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC90', 'has_quantitative_value': ['5.959']} DrugCentral uuid:5cb52322-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.287']} DrugCentral uuid:5cb54d16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kact', 'has_quantitative_value': ['5.155']} DrugCentral uuid:5cb575fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.269']} DrugCentral uuid:5cb59f1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5cb5c804-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.691']} DrugCentral uuid:5cb5f0d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:5cb6199e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:5cb645c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P27695 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Enzyme (DNA-(apurinic or apyrimidinic site) lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5cb66e94-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.748']} DrugCentral uuid:5cb6975c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5cb6c088-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5cb6e946-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5cb7120e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:5cb73bee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5cb7651a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5cb78df6-6b31-11ec-b3df-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5cb7b6b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P29372 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Enzyme (DNA-3-methyladenine glycosylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5cb7df68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63470 biolink:molecularly_interacts_with DrugCentral:1821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoxantrone targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5cb80af6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mivacurium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:5cb83738-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mivacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:5cb83738-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mivacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:5cb83738-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mivacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:5cb87054-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mizolastine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.456']} DrugCentral uuid:5cb89976-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mizolastine targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:5cb8bdf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mizolastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.84']} DrugCentral uuid:5cb8e6c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5cb90fa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5cb93980-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:5cb9628e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5cb98b74-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.97']} DrugCentral uuid:5cb9b446-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5cb9e006-6b31-11ec-b3df-0242ac110002 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:1825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moclobemide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:5cba0be4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5cba34f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.837']} DrugCentral uuid:5cba5dba-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:5cba82ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.396']} DrugCentral uuid:5cbaab80-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets Enzyme (Cytochrome P450 2C19) DrugCentral uuid:5cbad006-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5cbaf8d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 modafinil targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5cbb2312-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moexipril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.59']} DrugCentral uuid:5cbb4be4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5cbb74c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5cbb9edc-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5cbbcaa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mofezolac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5cbbf4a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.157']} DrugCentral uuid:5cbc1d62-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5cbc46ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.907']} DrugCentral uuid:5cbc6f88-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.421']} DrugCentral uuid:5cbc9882-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5cbcc154-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5cbceab2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.997']} DrugCentral uuid:5cbd138e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:5cbd3c74-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:5cbd6550-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.254']} DrugCentral uuid:5cbd91e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5cbdbab4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5cbde390-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5cbe0cda-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.763']} DrugCentral uuid:5cbe35b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5cbe5e88-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5cbe875a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5cbeb090-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molindone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5cbed994-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 molsidomine targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5cbf0248-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mometasone furoate targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.13']} DrugCentral uuid:5cbf2c1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mometasone furoate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:5cbf5658-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mometasone furoate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.9']} DrugCentral uuid:5cbf7f20-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.429']} DrugCentral uuid:5cbfa7ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.992']} DrugCentral uuid:5cbfd0a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.414']} DrugCentral uuid:5cbffa04-6b31-11ec-b3df-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone is inhibitor of Enzyme (Tyrosinase) DrugCentral uuid:5cc01f0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 monobenzone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.311']} DrugCentral uuid:5cc047f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5cc070e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.833']} DrugCentral uuid:5cc09a2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.574']} DrugCentral uuid:5cc0c312-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5cc0ec02-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:5cc114ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.713']} DrugCentral uuid:5cc13edc-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.853']} DrugCentral uuid:5cc167b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.495']} DrugCentral uuid:5cc19080-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.115']} DrugCentral uuid:5cc1b9d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:5cc1e2ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.611']} DrugCentral uuid:5cc20ba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.958']} DrugCentral uuid:5cc23472-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.772']} DrugCentral uuid:5cc25dbc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5cc28698-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.328']} DrugCentral uuid:5cc2b0b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.495']} DrugCentral uuid:5cc2d986-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.328']} DrugCentral uuid:5cc303b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.817']} DrugCentral uuid:5cc32daa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5cc35686-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.068']} DrugCentral uuid:5cc37f4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.895']} DrugCentral uuid:5cc3a88e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5cc3d19c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13304 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast targets GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:5cc3fa82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6NS65 biolink:molecularly_interacts_with DrugCentral:1836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 montelukast is antagonist of GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5cc42336-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5cc44c62-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:5cc47548-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1837 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.134']} DrugCentral uuid:5cc49e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1842 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moracizine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5cc4c408-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.86']} DrugCentral uuid:5cc4ed20-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:5cc515e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5cc53ee2-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5cc56804-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:5cc590ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:5cc5b9c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:5cc5e2b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5cc60bd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5cc6354a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:5cc65e12-6b31-11ec-b3df-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:5cc686e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5cc6b2d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P79350 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5cc6dbbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P47748 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:5cc7100a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5cc7100a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5cc7100a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5cc7100a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5cc76df2-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:5cc76df2-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:5cc76df2-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:5cc76df2-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:5cc76df2-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:5cc7d206-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:5cc7d206-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:5cc7d206-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:5cc7d206-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:5cc81ea0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q98UH1 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Mu opioid receptor-like OR2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:5cc84772-6b31-11ec-b3df-0242ac110002 UniProtKB:B3DH72 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor, delta 1b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5cc871ac-6b31-11ec-b3df-0242ac110002 UniProtKB:O57585 biolink:molecularly_interacts_with DrugCentral:1845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 morphine targets GPCR (Opioid receptor homologue) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:5cc89c22-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapramine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:5cc8c508-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapramine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:5cc8ede4-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:5cc9177e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:5cc9403c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.891']} DrugCentral uuid:5cc96918-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5cc991fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:5cc9bb2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.694']} DrugCentral uuid:5cc9e3fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.725']} DrugCentral uuid:5cca0cec-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.683']} DrugCentral uuid:5cca35b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5cca602a-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5cca89d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5ccab2a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:5ccadc08-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5ccb089a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5ccb089a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5ccb3d92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:1848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mosapride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5ccb6678-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:1851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latamoxef is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.938']} DrugCentral uuid:5ccb8fea-6b31-11ec-b3df-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:1851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latamoxef is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.716']} DrugCentral uuid:5ccbb8a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:1851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latamoxef is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.637']} DrugCentral uuid:5ccbe184-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5ccc05f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5ccc3102-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5ccc5da8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:5ccc5da8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:5ccc911a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin is inhibitor of Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5ccc911a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1854 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxifloxacin is inhibitor of Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5cccc676-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5cccef5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.397']} DrugCentral uuid:5ccd182e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5ccd4114-6b31-11ec-b3df-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5ccd6a36-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5ccd92ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:5ccdbbe4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:1856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxonidine is agonist of Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:5ccde4ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P00956 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin targets Enzyme (Isoleucine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5cce0e8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41252 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin targets Enzyme (Isoleucine--tRNA ligase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5cce3754-6b31-11ec-b3df-0242ac110002 UniProtKB:P41972 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin is inhibitor of Enzyme (Isoleucine--tRNA ligase) DrugCentral uuid:5cce5bf8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99YW3 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin is inhibitor of Enzyme (Isoleucine--tRNA ligase) DrugCentral uuid:5cce816e-6b31-11ec-b3df-0242ac110002 UniProtKB:P56690 biolink:molecularly_interacts_with DrugCentral:1857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mupirocin targets Enzyme (Isoleucine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5cceab12-6b31-11ec-b3df-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolate mofetil is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:5cced434-6b31-11ec-b3df-0242ac110002 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:1859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolate mofetil is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:5ccefe50-6b31-11ec-b3df-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid targets Enzyme (Inosine-5'-monophosphate dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5ccf279a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid targets Enzyme (Inosine-5'-monophosphate dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5ccf5468-6b31-11ec-b3df-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase (IMPDH)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5ccf5468-6b31-11ec-b3df-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase (IMPDH)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5ccf894c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5KP44 biolink:molecularly_interacts_with DrugCentral:1860 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mycophenolic acid targets Unclassified (Inosine-5'-monophosphate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5ccfb228-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabilone is agonist of GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5ccfde24-6b31-11ec-b3df-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:1862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabilone targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5cd0078c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:1862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabilone targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:5cd03054-6b31-11ec-b3df-0242ac110002 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:1862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabilone targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5cd059c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:5cd07e38-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.34']} DrugCentral uuid:5cd0a700-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.732']} DrugCentral uuid:5cd0cfe6-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5cd0f912-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nabumetone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.001']} DrugCentral uuid:5cd124aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nadolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5cd14d90-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nadolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5cd17658-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nadolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5cd1a0e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5cd1cc98-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:5cd1f5c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is inhibitor of Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5cd21e8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06870 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Kallikrein-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5cd24808-6b31-11ec-b3df-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5cd27224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:5cd29b8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00736 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is inhibitor of Enzyme (Complement C1r subcomponent) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5cd2c4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P09871 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Complement C1s subcomponent) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5cd2eeac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16515 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is blocker of Ion channel (Acid-sensing ion channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5cd31774-6b31-11ec-b3df-0242ac110002 UniProtKB:P78348 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is blocker of Ion channel (Acid-sensing ion channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5cd34032-6b31-11ec-b3df-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5cd36a08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHC3 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is blocker of Ion channel (Acid-sensing ion channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5cd39352-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15661 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is inhibitor of Enzyme (Tryptase alpha/beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:5cd3bc10-6b31-11ec-b3df-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:5cd3e4e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04756 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat targets Enzyme (Hepatocyte growth factor activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5cd40e54-6b31-11ec-b3df-0242ac110002 UniProtKB:O15393 biolink:molecularly_interacts_with DrugCentral:1867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafamostat is inhibitor of Enzyme (Transmembrane protease serine 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5cd43794-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:1868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafarelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.699']} DrugCentral uuid:5cd4607a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5cd49428-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5cd49428-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5cd49428-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5cd49428-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5cd49428-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:1869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nafcillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5cd4e284-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftidrofuryl targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5cd50b4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5cd53446-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5cd5613c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14534 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Enzyme (Squalene monooxygenase) DrugCentral uuid:5cd585cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4JEY0 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine is inhibitor of Enzyme (Squalene epoxidase) DrugCentral uuid:5cd5aa3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.51']} DrugCentral uuid:5cd5d34c-6b31-11ec-b3df-0242ac110002 UniProtKB:O07855 biolink:molecularly_interacts_with DrugCentral:1872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftifine targets Enzyme (Dehydrosqualene desaturase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:5cd5fd54-6b31-11ec-b3df-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5cd62dc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5cd62dc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5cd62dc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5cd677de-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:5cd677de-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:5cd677de-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:5cd6b8d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.432']} DrugCentral uuid:5cd6e1c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.921']} DrugCentral uuid:5cd70ab4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naftopidil is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:5cd7376e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalbuphine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5cd76068-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalbuphine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5cd7894e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalbuphine is agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5cd7b2fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalbuphine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5cd7db9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalidixic acid targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5cd8084c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalidixic acid is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5cd8084c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalidixic acid is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5cd83736-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.53']} DrugCentral uuid:5cd860a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:5cd88a24-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.04']} DrugCentral uuid:5cd8b30a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:5cd8dbd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:5cd90724-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalmefene targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5cd93000-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:5cd958f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:5cd9824e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.42']} DrugCentral uuid:5cd9ab48-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5cd9d424-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5cd9fe0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5cda32ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5cda32ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5cda32ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5cda32ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5cda8a90-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:5cda8a90-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:5cda8a90-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:5cda8a90-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:5cdada54-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:5cdb0466-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5cdb2d42-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5cdb5650-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5cdb7f2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.27']} DrugCentral uuid:5cdba81c-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5cdbd0ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5cdbfa1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:5cdc22f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5cdc4bbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5cdc74a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5cdc9e98-6b31-11ec-b3df-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5cdcca08-6b31-11ec-b3df-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone is antagonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5cdcf2da-6b31-11ec-b3df-0242ac110002 UniProtKB:P79350 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5cdd1b98-6b31-11ec-b3df-0242ac110002 UniProtKB:P51682 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.98']} DrugCentral uuid:5cdd5018-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5cdd5018-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5cdd5018-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5cdd5018-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5cdd9e38-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:5cddc2be-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:5cddec1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5cde14f8-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:5cde3dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.678']} DrugCentral uuid:5cde6804-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:5cde90e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:5cdeb570-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.14']} DrugCentral uuid:5cdede56-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5cdf08f4-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5cdf31d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:5cdf5ab6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone decanoate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.65']} DrugCentral uuid:5cdf8392-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone phenpropionate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5cdfacf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nandrolone phenpropionate is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.5']} DrugCentral uuid:5cdfd5cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5cdffec6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5ce027b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5ce0538a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:5ce07fa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5ce0aa2e-6b31-11ec-b3df-0242ac110002 UniProtKB:O09114 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Prostaglandin-H2 D-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5ce0d300-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5ce0fc4a-6b31-11ec-b3df-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5ce12512-6b31-11ec-b3df-0242ac110002 UniProtKB:P15304 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Hormone-sensitive lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5ce152a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5ce152a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naproxen targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5ce18912-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:5ce1b284-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:5ce1db7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.796']} DrugCentral uuid:5ce20446-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5ce22e3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1884 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naratriptan is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5ce2572a-6b31-11ec-b3df-0242ac110002 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5ce28402-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5ce28402-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5ce2bd50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:5ce2bd50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nateglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:5ce2f22a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5ce31b24-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5ce343f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5ce36d36-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5ce39612-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1887 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nebivolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5ce3bef8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:1889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nedocromil targets GPCR (Cysteinyl leukotriene receptor 1) DrugCentral uuid:5ce3e536-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nedocromil is agonist of GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.013']} DrugCentral uuid:5ce410ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.745']} DrugCentral uuid:5ce439e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5ce462cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5ce48c2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.444']} DrugCentral uuid:5ce4b51a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:5ce4de0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5ce507d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.143']} DrugCentral uuid:5ce53120-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.789']} DrugCentral uuid:5ce559e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.635']} DrugCentral uuid:5ce58350-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.432']} DrugCentral uuid:5ce5ac36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.444']} DrugCentral uuid:5ce5d8aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:5ce60460-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5ce62d3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:5ce6567c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:5ce67f62-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5ce6a83e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5ce6d11a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5ce6fa3c-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:5ce722f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5ce74bae-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:5ce77480-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5ce79b22-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:5ce7c534-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:5ce7ee1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.773']} DrugCentral uuid:5ce8185e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.481']} DrugCentral uuid:5ce8419e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.252']} DrugCentral uuid:5ce86a84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nefopam targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:5ce89356-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.232']} DrugCentral uuid:5ce8bcfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.189']} DrugCentral uuid:5ce8e644-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5ce91024-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5ce938ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.057']} DrugCentral uuid:5ce9633a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.209']} DrugCentral uuid:5ce98e0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.592']} DrugCentral uuid:5ce9b70e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.909']} DrugCentral uuid:5ce9dfea-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.078']} DrugCentral uuid:5cea092a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.842']} DrugCentral uuid:5cea31f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.632']} DrugCentral uuid:5cea5ace-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.255']} DrugCentral uuid:5cea838c-6b31-11ec-b3df-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:5ceaa88a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.101']} DrugCentral uuid:5cead15c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.098']} DrugCentral uuid:5ceafa42-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.676']} DrugCentral uuid:5ceb2300-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.648']} DrugCentral uuid:5ceb4ea2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.739']} DrugCentral uuid:5ceb79f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.009']} DrugCentral uuid:5ceba2e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.615']} DrugCentral uuid:5cebcbb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:5cebf53c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.236']} DrugCentral uuid:5cec1ea4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:5cec479e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:5cec70de-6b31-11ec-b3df-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:5cec99b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:1893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nelfinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.68']} DrugCentral uuid:5cecc296-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5ceceb7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:5ced155c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:5ced3f0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:5ced67fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.31']} DrugCentral uuid:5ced90c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nemonapride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:5cedba66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5cede310-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A7S3 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Cytosolic other (30S ribosomal protein S12) DrugCentral uuid:5cee078c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08312 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Enzyme (Phenylalanine--tRNA ligase alpha subunit) DrugCentral uuid:5cee2c1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07395 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Enzyme (Phenylalanine--tRNA ligase beta subunit) DrugCentral uuid:5cee50e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5cee79c4-6b31-11ec-b3df-0242ac110002 UniProtKB:O95237 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Enzyme (Lecithin retinol acyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:5ceea28c-6b31-11ec-b3df-0242ac110002 UniProtKB:O00255 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin targets Unclassified (Menin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.81']} DrugCentral uuid:5ceecb54-6b31-11ec-b3df-0242ac110002 UniProtKB:P48442 biolink:molecularly_interacts_with DrugCentral:1896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 framycetin is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:5ceef714-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:5cef1ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5cef48cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.34']} DrugCentral uuid:5cef7180-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:5cef9af2-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5cefc3b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5cefec8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5cf01540-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5cf04236-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5cf04236-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5cf07ad0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5cf07ad0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:1899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepafenac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5cf0af96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1900 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nepinalone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:5cf0dbd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nesiritide is agonist of Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:5cf10068-6b31-11ec-b3df-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:5cf12a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5cf153ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5cf17cb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5cf1a590-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:1904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nevirapine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5cf1ce62-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets GPCR (Hydroxycarboxylic acid receptor 2) DrugCentral uuid:5cf1f3c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P49019 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets GPCR (Hydroxycarboxylic acid receptor 3) DrugCentral uuid:5cf21836-6b31-11ec-b3df-0242ac110002 UniProtKB:P40261 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (Nicotinamide N-methyltransferase) DrugCentral uuid:5cf23ca8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15274 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (Nicotinate-nucleotide pyrophosphorylase [carboxylating]) DrugCentral uuid:5cf26156-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96EB6 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent protein deacetylase sirtuin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5cf28b54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IXJ6 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent protein deacetylase sirtuin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5cf2b430-6b31-11ec-b3df-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5cf2dcee-6b31-11ec-b3df-0242ac110002 UniProtKB:P53686 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent deacetylase HST2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:5cf305b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NTG7 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent deacetylase sirtuin 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5cf32f14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NXA8 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Enzyme (NAD-dependent protein deacylase sirtuin-5, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:5cf357dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8I6E4 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Unclassified (Putative silent information regulator 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5cf380b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:1906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinamide targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:5cf3a976-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.377']} DrugCentral uuid:5cf3d2ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5cf3fb74-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5cf4243c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:5cf448cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:5cf4723e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5cf49af2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.553']} DrugCentral uuid:5cf4c39c-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.553']} DrugCentral uuid:5cf4ec78-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:5cf515fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5cf53fca-6b31-11ec-b3df-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5cf569d2-6b31-11ec-b3df-0242ac110002 UniProtKB:O54698 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5cf592b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5cf5c3a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5cf5c3a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5cf5c3a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5cf60c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5cf60c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5cf60c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5cf65824-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:5cf65824-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:5cf65824-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:5cf69e24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:5cf69e24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:5cf6cdb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5cf6f68a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15385 biolink:molecularly_interacts_with DrugCentral:1909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicardipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5cf71f52-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.046']} DrugCentral uuid:5cf74806-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:5cf77146-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5cf79a18-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5cf7c2f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5cf7eba8-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5cf81556-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:5cf83e1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:5cf8677c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:5cf8913e-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:5cf8ba7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:5cf8e33c-6b31-11ec-b3df-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:5cf90c18-6b31-11ec-b3df-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:5cf934e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5JUK3 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide is activator of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5cf95e3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5cf98710-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:1912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niclosamide targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5cf9afec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:1919 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicorandil targets Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.886']} DrugCentral uuid:5cf9d8b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P48048 biolink:molecularly_interacts_with DrugCentral:1919 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicorandil targets Ion channel (ATP-sensitive inward rectifier potassium channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:5cfa0280-6b31-11ec-b3df-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1919 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicorandil targets Enzyme (Atrial natriuretic peptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5cfa2b3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5cfa541a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5cfa7d46-6b31-11ec-b3df-0242ac110002 UniProtKB:P11509 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Enzyme (Cytochrome P450 2A6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.356']} DrugCentral uuid:5cfaa604-6b31-11ec-b3df-0242ac110002 UniProtKB:P58154 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Unclassified (Acetylcholine-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5cfaceea-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5cfaf7b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5cfb2142-6b31-11ec-b3df-0242ac110002 UniProtKB:P09483 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.03']} DrugCentral uuid:5cfb4a32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5cfb7304-6b31-11ec-b3df-0242ac110002 UniProtKB:P49582 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:5cfb9d48-6b31-11ec-b3df-0242ac110002 UniProtKB:P43144 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5cfbc6f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit beta-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:5cfbeffa-6b31-11ec-b3df-0242ac110002 UniProtKB:P04757 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:5cfc18e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12389 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5cfc41da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WSF8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Unclassified (Soluble acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5cfc6c0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5cfc94d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21687 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Enzyme (Lycopene cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5cfcbda4-6b31-11ec-b3df-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:5cfce68a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25162 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit beta-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5cfd0fe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P09482 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:5cfd38ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O70174 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5cfd6560-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5cfd6560-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5cfd9ef4-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5cfd9ef4-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5cfdd7c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5cfdd7c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5cfe10fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5cfe10fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5cfe4a52-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5cfe4a52-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5cfe8314-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5cfe8314-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cfee598-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JLB5 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:5cffa37a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5cffa37a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5cffdc46-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:5cffdc46-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:5d0015da-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:5d0015da-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:5d00502c-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:5d00502c-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:5d008902-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5d008902-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5d00cd7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:5d00cd7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:5d00cd7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:5d00cd7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:5d00cd7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.15']} DrugCentral uuid:5d013294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:5d013294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:5d013294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:5d013294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:5d018d0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5d018d0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5d018d0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5d018d0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15825 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5d01de4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5d01de4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5d021e98-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5d021e98-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5d021e98-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5d021e98-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5d027b0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5d027b0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5d027b0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5d027b0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5d027b0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5d02d392-6b31-11ec-b3df-0242ac110002 UniProtKB:P02708 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5d02fc96-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.35']} DrugCentral uuid:5d0328f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5d035218-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62897 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine is blocker of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5d037ad6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:1920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotine targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5d03a43e-6b31-11ec-b3df-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.089']} DrugCentral uuid:5d03cd24-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.65']} DrugCentral uuid:5d03f6f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5d041fb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5d0448e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.495']} DrugCentral uuid:5d0471d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.019']} DrugCentral uuid:5d049ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.348']} DrugCentral uuid:5d04c396-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5d04ee70-6b31-11ec-b3df-0242ac110002 UniProtKB:P00390 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Glutathione reductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:5d051742-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.658']} DrugCentral uuid:5d054154-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5d056a76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d0593e8-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:5d05bcb0-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.672']} DrugCentral uuid:5d05e596-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:5d060e5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09470 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:5d0637a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5d06607a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5d068974-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.355']} DrugCentral uuid:5d06b390-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is antagonist of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5d06dcbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P16389 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium voltage-gated channel subfamily A member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5d07058e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:5d072e4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.731']} DrugCentral uuid:5d0757c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.072']} DrugCentral uuid:5d0780ae-6b31-11ec-b3df-0242ac110002 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d07a976-6b31-11ec-b3df-0242ac110002 UniProtKB:O75311 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is antagonist of Ion channel (Glycine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5d07d32e-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.821']} DrugCentral uuid:5d07fc78-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5d08255e-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5d084e3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:5d08772a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5d08a11e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:5d08ca2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:5d08f312-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5d091c70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5d09454c-6b31-11ec-b3df-0242ac110002 UniProtKB:O35505 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.59']} DrugCentral uuid:5d0975e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:5d0975e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:5d0975e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:5d09be8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:5d09be8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:5d09be8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:5d09ff5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:5d0a2840-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:5d0a5112-6b31-11ec-b3df-0242ac110002 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5d0a7c8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P16388 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5d0aa54a-6b31-11ec-b3df-0242ac110002 UniProtKB:P63142 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5d0acebc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8HY88 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5d0af860-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1922 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifedipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5d0b213c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifekalant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5d0b4b08-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifekalant targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:5d0b73e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifekalant targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5d0b9e5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifekalant targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5d0bc722-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.037']} DrugCentral uuid:5d0beff4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.973']} DrugCentral uuid:5d0c18d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5d0c4256-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5d0c6b32-6b31-11ec-b3df-0242ac110002 UniProtKB:P51800 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid is activator of Ion channel (Chloride channel protein ClC-Ka) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5d0c940e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6UVM3 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid is activator of Ion channel (Potassium channel subfamily T member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:5d0cbccc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5d0ce652-6b31-11ec-b3df-0242ac110002 UniProtKB:P51801 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid is activator of Ion channel (Chloride channel protein ClC-Kb) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5d0d0f06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:1925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niflumic acid targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5d0d37ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:1928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifuroxazide targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5d0d60be-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:5d0d8a1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:5d0db2e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:5d0ddbde-6b31-11ec-b3df-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5d0e05f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:5d0e2f30-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5d0e57f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5d0e80d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:5d0eaa64-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5d0ed34a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5d0efc1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.83']} DrugCentral uuid:5d0f2502-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5d0f4f50-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5d0f78ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.33']} DrugCentral uuid:5d0fa180-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5d0fca52-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5d0ff6b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5d10201a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5d1048f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5d10724a-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5d109b26-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5d10c484-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:5d10ed60-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.13']} DrugCentral uuid:5d11168c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.387']} DrugCentral uuid:5d113f68-6b31-11ec-b3df-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:5d11683a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5d11910c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:5d11bc72-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:5d11e544-6b31-11ec-b3df-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5d120e0c-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.069']} DrugCentral uuid:5d1236e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5d12601e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5d128a30-6b31-11ec-b3df-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:5d12b302-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:5d12dbca-6b31-11ec-b3df-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.318']} DrugCentral uuid:5d130514-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:5d132de6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.096']} DrugCentral uuid:5d1357a8-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5d1381e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:5d13aae6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15759 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:5d13d3b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5d13fc94-6b31-11ec-b3df-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5d1425ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.141']} DrugCentral uuid:5d144e7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5d147782-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5d14a054-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5d14c980-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:5d14f248-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5d151b2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5d154414-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5d156f16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5d1597de-6b31-11ec-b3df-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5d15c0c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:5d15e9a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:5d161308-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5d163bf8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5d1664ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:5d168e00-6b31-11ec-b3df-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5d16b6dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5d16dfae-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5d170876-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5d1732ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5d175df8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5d1786c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5d17afa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5d17d918-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:5d180280-6b31-11ec-b3df-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:5d182b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P54753 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5d185438-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5d187d82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5d18a65e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d18cf3a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5d18f82a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5d192570-6b31-11ec-b3df-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5d1955d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:5d1955d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:1932 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilotinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:5d198ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1933 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d19b404-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:5d19d88a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:5d19fce8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:5d1a254c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:5d1a254c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nilvadipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:5d1a54b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:5d1a7d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5d1aa648-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.927']} DrugCentral uuid:5d1acfec-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5d1afc38-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5d1b2550-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5d1b4f1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.632']} DrugCentral uuid:5d1b785c-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5d1ba12e-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5d1bc9ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2A865 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide is inhibitor of Transporter (Sodium-dependent neutral amino acid transporter B(0)AT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5d1bf2d2-6b31-11ec-b3df-0242ac110002 UniProtKB:L8I2E6 biolink:molecularly_interacts_with DrugCentral:1935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimesulide targets Enzyme (Dipeptidyl peptidase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.16']} DrugCentral uuid:5d1c1c12-6b31-11ec-b3df-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.364']} DrugCentral uuid:5d1c44f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:5d1c6de8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5d1c96a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.072']} DrugCentral uuid:5d1cc16c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5d1cea2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:5d1d0eba-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5d1d378c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) DrugCentral uuid:5d1d5c94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:5d1d8110-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d1da9ba-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.252']} DrugCentral uuid:5d1dd282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d1dfbd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:5d1e2494-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5d1e4e06-6b31-11ec-b3df-0242ac110002 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d1e76ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5d1ea3e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:5d1ecdc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5d1ef69e-6b31-11ec-b3df-0242ac110002 UniProtKB:P27732 biolink:molecularly_interacts_with DrugCentral:1937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nimodipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5d1f1fc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.642']} DrugCentral uuid:5d1f4996-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.638']} DrugCentral uuid:5d1f724a-6b31-11ec-b3df-0242ac110002 UniProtKB:O00555 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) DrugCentral uuid:5d1f96d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.395']} DrugCentral uuid:5d1fc01a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5d1fea54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) DrugCentral uuid:5d200ec6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:5d2037ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d2069ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5d2069ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5d2069ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5d20aaa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01815 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5d20d374-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99246 biolink:molecularly_interacts_with DrugCentral:1942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nisoldipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5d20fca0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:1943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitazoxanide targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5d212572-6b31-11ec-b3df-0242ac110002 UniProtKB:Q968X7 biolink:molecularly_interacts_with DrugCentral:1943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitazoxanide is inhibitor of Enzyme (Pyruvate dehydrogenase [NADP(+)]) DrugCentral uuid:5d214a0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q24982 biolink:molecularly_interacts_with DrugCentral:1943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitazoxanide is inhibitor of Enzyme (Pyruvate:ferredoxin oxidoreductase) DrugCentral uuid:5d216e7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0P8E1 biolink:molecularly_interacts_with DrugCentral:1943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitazoxanide targets Enzyme (Pyruvate-flavodoxin oxidoreductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5d2197c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P32754 biolink:molecularly_interacts_with DrugCentral:1944 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitisinone is inhibitor of Enzyme (4-hydroxyphenylpyruvate dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:5d21c086-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02110 biolink:molecularly_interacts_with DrugCentral:1944 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitisinone targets Enzyme (4-hydroxyphenylpyruvate dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5d21e96c-6b31-11ec-b3df-0242ac110002 UniProtKB:P32755 biolink:molecularly_interacts_with DrugCentral:1944 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitisinone targets Unclassified (4-hydroxyphenylpyruvate dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5d2219f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5d2219f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5d2219f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5d227292-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5d227292-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5d227292-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5d227292-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5d227292-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5d227292-6b31-11ec-b3df-0242ac110002 UniProtKB:P22300 biolink:molecularly_interacts_with DrugCentral:1945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5d22d912-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5d2301ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.081']} DrugCentral uuid:5d232ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is blocker of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5d23539c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) DrugCentral uuid:5d23c5a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.921']} DrugCentral uuid:5d23f194-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01668 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5d241d04-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:5d244662-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.056']} DrugCentral uuid:5d246f48-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:5d2498e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O60840 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d24c1aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5d24eb94-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5d25145c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d253dc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is gating inhibitor of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d2566dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P21556 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:5d259788-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5d259788-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5d259788-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5d25db4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:1947 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrendipine is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:5d260fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5d260fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5d260fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5d260fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1948 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitric oxide is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5d2654c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:1949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrofurantoin targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:5d2679c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:1949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrofurantoin targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:5d26a2a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:1950 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrofurazone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:5d26c766-6b31-11ec-b3df-0242ac110002 UniProtKB:P83512 biolink:molecularly_interacts_with DrugCentral:1950 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitrofurazone targets Enzyme (Snake venom metalloproteinase Bap1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:5d26f04c-6b31-11ec-b3df-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:5d2720c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5d2720c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5d2720c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5d2720c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:1952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glyceryl trinitrate is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:5d27646e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5d278d9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5d27b81a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:5d27e0e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5d2809dc-6b31-11ec-b3df-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5d2832c2-6b31-11ec-b3df-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:1954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroxoline targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5d285c5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nizatidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5d288542-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:1955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nizatidine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.251']} DrugCentral uuid:5d28ae0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5d28d6fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:5d29003a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:5d292916-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5d2951fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:5d297bfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['2.947']} DrugCentral uuid:5d29a5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.963']} DrugCentral uuid:5d29ce84-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5d29f760-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:5d2a21e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5d2a4ada-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5d2a7776-6b31-11ec-b3df-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Enzyme (Hemoglobin HbA) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.678']} DrugCentral uuid:5d2a7776-6b31-11ec-b3df-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:1958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nomifensine targets Enzyme (Hemoglobin HbA) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.678']} DrugCentral uuid:5d2aac5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norelgestromin is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:5d2ad1c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5d2afade-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5d2b23c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5d2b4dae-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5d2b76da-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:5d2b9fe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5d2bc8d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5d2bf36c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.367']} DrugCentral uuid:5d2c1c7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5d2c4556-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.071']} DrugCentral uuid:5d2c6e3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5d2c97ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.69']} DrugCentral uuid:5d2cc094-6b31-11ec-b3df-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:5d2ce97a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5d2d1256-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5d2d3e48-6b31-11ec-b3df-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5d2d683c-6b31-11ec-b3df-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5d2d910e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:5d2dba08-6b31-11ec-b3df-0242ac110002 UniProtKB:P10608 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5d2de37a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:5d2e0cce-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5d2e3e60-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:5d2e3e60-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:5d2e3e60-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:5d2e874e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5d2e874e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5d2e874e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5d2edb36-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5d2edb36-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5d2edb36-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5d2edb36-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5d2edb36-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5d2edb36-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5d2f488c-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d2f488c-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d2f488c-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d2f895a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01337 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5d2fb2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:1960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norepinephrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5d2fdbe4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.618']} DrugCentral uuid:5d3004c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.706']} DrugCentral uuid:5d302e00-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.636']} DrugCentral uuid:5d3056d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:5d307fa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['11.26']} DrugCentral uuid:5d30a86c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.97']} DrugCentral uuid:5d30d2b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5d30fc22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.914']} DrugCentral uuid:5d3129cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:5d3129cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:1962 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethisterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:5d315e9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5d31893a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.533']} DrugCentral uuid:5d31b234-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5d31db10-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:5d32048c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['11.26']} DrugCentral uuid:5d322d36-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:5d325612-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.97']} DrugCentral uuid:5d327eee-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.149']} DrugCentral uuid:5d32a946-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:1963 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethindrone acetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.441']} DrugCentral uuid:5d32d574-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1965 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethynodrel is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:5d32fc0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:1965 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norethynodrel targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:5d3324e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5d334e46-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5d33772c-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5d339fea-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5d33c8d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AFI2 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin is inhibitor of Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5d33f1f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C1U9 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Enzyme (DNA topoisomerase 4 subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5d341ae2-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WG47 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5d3443b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin is inhibitor of Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5d346c86-6b31-11ec-b3df-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5d34968e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5d34bf60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02880 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Enzyme (DNA topoisomerase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5d34e8fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d354ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d36285a-6b31-11ec-b3df-0242ac110002 UniProtKB:P37340 biolink:molecularly_interacts_with DrugCentral:1967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norfloxacin targets Unclassified (Multidrug resistance protein mdtK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.01']} DrugCentral uuid:5d3652d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:1968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norgestimate is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:5d36790e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13507 biolink:molecularly_interacts_with DrugCentral:1968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norgestimate is blocker of Ion channel (Short transient receptor potential channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5d36a1f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y210 biolink:molecularly_interacts_with DrugCentral:1968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 norgestimate is blocker of Ion channel (Short transient receptor potential channel 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5d36cad0-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5d36f596-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5d371e72-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.561']} DrugCentral uuid:5d37476c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:5d3771d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.36']} DrugCentral uuid:5d379b22-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.509']} DrugCentral uuid:5d37c408-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.356']} DrugCentral uuid:5d37ecda-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:5d3815c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5d3840c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:5d3869a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:5d38928e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5d38bc1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:5d38e4f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.033']} DrugCentral uuid:5d390dd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.639']} DrugCentral uuid:5d3936b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:5d395fe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.959']} DrugCentral uuid:5d3988ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:5d39b1d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.076']} DrugCentral uuid:5d39daae-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.013']} DrugCentral uuid:5d3a0470-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.071']} DrugCentral uuid:5d3a2d2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:5d3a5600-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.921']} DrugCentral uuid:5d3a7ee6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['6.225']} DrugCentral uuid:5d3aa88a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:5d3ad15c-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:5d3afa2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5d3b22ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.943']} DrugCentral uuid:5d3b4c54-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.837']} DrugCentral uuid:5d3b7616-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.4']} DrugCentral uuid:5d3b9ed4-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:5d3bc86e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:5d3bf154-6b31-11ec-b3df-0242ac110002 UniProtKB:P78508 biolink:molecularly_interacts_with DrugCentral:1971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nortriptyline is blocker of Ion channel (ATP-sensitive inward rectifier potassium channel 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.796']} DrugCentral uuid:5d3c1a26-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 noscapine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.087']} DrugCentral uuid:5d3c42ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 noscapine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:5d3c6c60-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 noscapine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5d3c953c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 noscapine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5d3cbe18-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:5d3ce6d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:5d3d102a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A4L9 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:5d3d3910-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7X1P7 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (ParE) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:5d3d6250-6b31-11ec-b3df-0242ac110002 UniProtKB:C3SLN2 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5d3d8f1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5d3d8f1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5d3dcad8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5HK04 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5d3dcad8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5HK04 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5d3dfa6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C559 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5d3e2334-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A0K8 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5d3e4cd8-6b31-11ec-b3df-0242ac110002 UniProtKB:A0QNE0 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNULL gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:5d3e7596-6b31-11ec-b3df-0242ac110002 UniProtKB:C3SLN3 biolink:molecularly_interacts_with DrugCentral:1974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 novobiocin targets Enzyme (DNULL gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5d3ea638-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buphenine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5d3ea638-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buphenine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5d3ea638-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 buphenine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5d3ee774-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:5d3f1082-6b31-11ec-b3df-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.699']} DrugCentral uuid:5d3f3a58-6b31-11ec-b3df-0242ac110002 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5d3f6348-6b31-11ec-b3df-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:5d3f8f12-6b31-11ec-b3df-0242ac110002 UniProtKB:P30875 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide targets GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.55']} DrugCentral uuid:5d3fb866-6b31-11ec-b3df-0242ac110002 UniProtKB:P30935 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide targets GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5d3fe138-6b31-11ec-b3df-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5d400a28-6b31-11ec-b3df-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.98']} DrugCentral uuid:5d4033ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:5d405c9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30680 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5d40857a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30936 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5d40aeec-6b31-11ec-b3df-0242ac110002 UniProtKB:O08858 biolink:molecularly_interacts_with DrugCentral:1980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octreotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:5d40d7dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.23']} DrugCentral uuid:5d4100c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5d412994-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:5d415446-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin is inhibitor of Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5d417dd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES7 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Enzyme (DNA gyrase subunit B) DrugCentral uuid:5d41a25c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5d41cb2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P03362 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Polyprotein (Gag-Pro-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d422d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d430b88-6b31-11ec-b3df-0242ac110002 UniProtKB:P47154 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Enzyme (CAAX prenyl protease 1) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:5d43372a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:1981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofloxacin targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:5d4361f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5d438ac2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5d43b39e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:5d43dd1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.523']} DrugCentral uuid:5d440600-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.492']} DrugCentral uuid:5d442edc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5d445812-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5d4480ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5d44a9d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.319']} DrugCentral uuid:5d44d29c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:5d44fc22-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:5d45251c-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:5d454de4-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:5d457800-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:5d45a186-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.086']} DrugCentral uuid:5d45cb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.097']} DrugCentral uuid:5d45f46a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.046']} DrugCentral uuid:5d461d3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:5d46467c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.356']} DrugCentral uuid:5d466f62-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.506']} DrugCentral uuid:5d469848-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.102']} DrugCentral uuid:5d46c1a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.136']} DrugCentral uuid:5d46eafa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.682']} DrugCentral uuid:5d4713d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.046']} DrugCentral uuid:5d473cc6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:5d476606-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.233']} DrugCentral uuid:5d478eba-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.121']} DrugCentral uuid:5d47b796-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:5d47e068-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:5d4809e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:5d4832a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:5d485b88-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:5d488446-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.916']} DrugCentral uuid:5d48aee4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.509']} DrugCentral uuid:5d48d7d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5d4900ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.558']} DrugCentral uuid:5d492982-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:5d4952cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.364']} DrugCentral uuid:5d497cc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5d49a588-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5d49cff4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5d49f8f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5d4a21de-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5d4a4ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5d4a74ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:5d4aa0be-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5d4acb20-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d4af406-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5d4b1d5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:5d4b462c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5d4b6f08-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5d4b97da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5d4bc908-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5d4bc908-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5d4bc908-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5d4c1188-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5d4c1188-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5d4c1188-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5d4c53f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5d4c7cb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:1982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olanzapine targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5d4ca6a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:1985 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olmesartan medoxomil is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5d4ccf4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:1985 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olmesartan medoxomil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.09']} DrugCentral uuid:5d4cf896-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olopatadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.284']} DrugCentral uuid:5d4d217c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:1986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olopatadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5d4d4e54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olprinone is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:5d4d4e54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:1987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olprinone is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:5d4d7f32-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:1988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olsalazine is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:5d4da3b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:1988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olsalazine is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) DrugCentral uuid:5d4dcc26-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olsalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:5d4dcc26-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:1988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olsalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:5d4dfb06-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5d4e257c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08473 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d4e4f16-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5d4e77d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07861 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Enzyme (Neprilysin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5d4ea0a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5d4ec9d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:1989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omapatrilat targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5d4ef286-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.31']} DrugCentral uuid:5d4f1b4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.051']} DrugCentral uuid:5d4f43ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.347']} DrugCentral uuid:5d4f6d60-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:5d4f960a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5d4fc01c-6b31-11ec-b3df-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5d4fee0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5d4fee0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5d5026a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P19156 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5d5026a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P19156 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5d505b8a-6b31-11ec-b3df-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5d50843e-6b31-11ec-b3df-0242ac110002 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5d50ad6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5d50da10-6b31-11ec-b3df-0242ac110002 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:5d50da10-6b31-11ec-b3df-0242ac110002 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:1990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omeprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:5d510ee0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.091']} DrugCentral uuid:5d51394c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:5d51621e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.678']} DrugCentral uuid:5d518ae6-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5d51b3b8-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:5d51dd2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5d5205fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5d522ed8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5d5257be-6b31-11ec-b3df-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5d528130-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5d52aa98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5d52d360-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5d52fcf0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5d5325e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35563 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:5d534ebc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5d5377b6-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d53a128-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5d53ca04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5d53f2d6-6b31-11ec-b3df-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:5d541f7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:5d541f7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:5d5458c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.34']} DrugCentral uuid:5d5458c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.34']} DrugCentral uuid:5d549542-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5d549542-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5d549542-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5d54db92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5d54db92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5d55106c-6b31-11ec-b3df-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:1992 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ondansetron targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5d553952-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:1993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opipramol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5d556238-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:1993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opipramol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5d558cb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:1993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opipramol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5d55b6f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5d55dfec-6b31-11ec-b3df-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Lipoprotein lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.18']} DrugCentral uuid:5d56092c-6b31-11ec-b3df-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5d5631ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4D2 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Sn1-specific diacylglycerol lipase alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5d565ab2-6b31-11ec-b3df-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5d568398-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NCG7 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Sn1-specific diacylglycerol lipase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5d56ad0a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95870 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Abhydrolase domain-containing protein 16A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5d56d5dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N2K0 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Monoacylglycerol lipase ABHD12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5d56feb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13093 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Platelet-activating factor acetylhydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5d5727b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00591 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Pancreatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5d5752a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BV23 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Monoacylglycerol lipase ABHD6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:5d577c8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6WQJ1 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Sn1-specific diacylglycerol lipase alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d57a566-6b31-11ec-b3df-0242ac110002 UniProtKB:P06858 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Lipoprotein lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.18']} DrugCentral uuid:5d57cec4-6b31-11ec-b3df-0242ac110002 UniProtKB:P11150 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Hepatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5d57f7f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5X9 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat targets Enzyme (Endothelial lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5d5820b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16233 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat is inhibitor of Enzyme (Pancreatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.9']} DrugCentral uuid:5d58498a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07098 biolink:molecularly_interacts_with DrugCentral:1996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orlistat is inhibitor of Enzyme (Gastric triacylglycerol lipase) DrugCentral uuid:5d586e24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.886']} DrugCentral uuid:5d5897a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.092']} DrugCentral uuid:5d58c18a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.174']} DrugCentral uuid:5d58ea3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.614']} DrugCentral uuid:5d59141e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.578']} DrugCentral uuid:5d593d68-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.903']} DrugCentral uuid:5d596644-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.666']} DrugCentral uuid:5d598f2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.553']} DrugCentral uuid:5d59b874-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.283']} DrugCentral uuid:5d59e150-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:5d5a0a4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:5d5a3312-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.165']} DrugCentral uuid:5d5a5c52-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:5d5a854c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.873']} DrugCentral uuid:5d5aae32-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:5d5ad70e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5d5b00a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:5d5b2998-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.889']} DrugCentral uuid:5d5b5274-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:5d5b7b50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.764']} DrugCentral uuid:5d5ba4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:5d5bce20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.201']} DrugCentral uuid:5d5bf6f2-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5d5c2032-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:5d5c5ff2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5d5c5ff2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5d5c5ff2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5d5c5ff2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5d5c5ff2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5d5c5ff2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5d5c5ff2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:1999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 orphenadrine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5d5cd4b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P06818 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.83']} DrugCentral uuid:5d5cfd72-6b31-11ec-b3df-0242ac110002 UniProtKB:P16207 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5d5d26e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P03468 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5d5d4fb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P03474 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:5d5d7950-6b31-11ec-b3df-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:5d5da218-6b31-11ec-b3df-0242ac110002 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5d5dcad6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75VQ4 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.81']} DrugCentral uuid:5d5df3f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6Q793 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:5d5e1cd4-6b31-11ec-b3df-0242ac110002 UniProtKB:A5Z252 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5d5e45b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2LFS1 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.31']} DrugCentral uuid:5d5e6eb4-6b31-11ec-b3df-0242ac110002 UniProtKB:C4LRQ6 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:5d5e98c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q20MD3 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:5d5ec1ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P03470 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:5d5eea7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q194T1 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5d5f1346-6b31-11ec-b3df-0242ac110002 UniProtKB:P03469 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.86']} DrugCentral uuid:5d5f3c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07599 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d5f6526-6b31-11ec-b3df-0242ac110002 UniProtKB:P03471 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.96']} DrugCentral uuid:5d5f8df8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XV28 biolink:molecularly_interacts_with DrugCentral:2001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oseltamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5d5fb6b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11172 biolink:molecularly_interacts_with DrugCentral:2002 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oteracil is inhibitor of Enzyme (Uridine 5'-monophosphate synthase) DrugCentral uuid:5d5fdb82-6b31-11ec-b3df-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:2004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ouabain targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.169']} DrugCentral uuid:5d600436-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ouabain targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.009']} DrugCentral uuid:5d602cea-6b31-11ec-b3df-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ouabain targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:5d60529c-6b31-11ec-b3df-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:2004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ouabain targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:5d607e0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5d60a6d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5d60cf7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5d60f404-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5d612c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5d612c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5d612c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5d612c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5d612c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XDB3 biolink:molecularly_interacts_with DrugCentral:2006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxacillin is inhibitor of Enzyme (Penicillin-binding protein) DrugCentral uuid:5d617a50-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxametacin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5d61a390-6b31-11ec-b3df-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:2008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxametacin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5d61d02c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxametacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5d61d02c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxametacin targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5d620506-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2011 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxandrolone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:5d622aae-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5d625556-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.068']} DrugCentral uuid:5d627e1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin targets GPCR (fMet-Leu-Phe receptor) DrugCentral uuid:5d62a2ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin is inhibitor of Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5d62cbf8-6b31-11ec-b3df-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5d62f542-6b31-11ec-b3df-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5d631e1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxaprozin targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:5d6346dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.056']} DrugCentral uuid:5d636f9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.148']} DrugCentral uuid:5d6398c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.203']} DrugCentral uuid:5d63c18e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:5d63eace-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d64160c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxatomide is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:5d6446a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:5d6446a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:5d6446a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:5d6488d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2017 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxcarbazepine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5d64add8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2026 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphencyclimine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5d64d27c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2026 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphencyclimine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:5d64f70c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxprenolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:5d651ff2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxprenolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5d654946-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxprenolol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5d657218-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxprenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:5d659b08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.991']} DrugCentral uuid:5d65c3da-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.589']} DrugCentral uuid:5d65ee8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.298']} DrugCentral uuid:5d6617ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.837']} DrugCentral uuid:5d6640da-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.09']} DrugCentral uuid:5d6669a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:5d6692f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5d66bbdc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.168']} DrugCentral uuid:5d66e4ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:5d670d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.086']} DrugCentral uuid:5d6736ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:5d675fa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.23']} DrugCentral uuid:5d678882-6b31-11ec-b3df-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:5d67b172-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5d67dcc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2028 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybutynin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:5d6805c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:5d682f3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5d685870-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5d68812e-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5d68aa0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5d68d3ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5d68fd20-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5d6925fc-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:5d694ece-6b31-11ec-b3df-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:5d69778c-6b31-11ec-b3df-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5d69a216-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:2029 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycodone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5d69cafc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:5d69f3e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.493']} DrugCentral uuid:5d6a1c96-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5d6a45e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:5d6a6eb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5d6a97a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.111']} DrugCentral uuid:5d6ac06a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.342']} DrugCentral uuid:5d6ae9a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.019']} DrugCentral uuid:5d6b12e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5d6b3bda-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5d6b65ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5d6b9184-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5d6bbace-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5d6be4ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5d6c0dee-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.379']} DrugCentral uuid:5d6c36d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.21']} DrugCentral uuid:5d6c5fba-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.162']} DrugCentral uuid:5d6c88a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.041']} DrugCentral uuid:5d6cb208-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:5d6cdad0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5d6d038e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:5d6d2c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.88']} DrugCentral uuid:5d6d5848-6b31-11ec-b3df-0242ac110002 UniProtKB:P18871 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:5d6d812e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5d6da9f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:5d6ddaf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:5d6ddaf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:5d6ddaf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:5d6e232c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5d6e232c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5d6e232c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5d6e63f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5d6e8e2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetazoline is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5d6eb6fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2033 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetholone targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:5d6edb82-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2033 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetholone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:5d6efffe-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2033 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymetholone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.863']} DrugCentral uuid:5d6f2be6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.444']} DrugCentral uuid:5d6f54c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:5d6f7dda-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone is agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5d6fa800-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.01']} DrugCentral uuid:5d6fd0dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5d6ff9d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.27']} DrugCentral uuid:5d7022d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5d704c38-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5d707514-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:5d709df0-6b31-11ec-b3df-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5d70d234-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:5d70d234-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:5d70d234-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:5d70d234-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.89']} DrugCentral uuid:5d7125cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:5d7125cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2034 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxymorphone targets GPCR (Opioid receptors; mu and delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:5d715a9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone targets GPCR (fMet-Leu-Phe receptor) DrugCentral uuid:5d717f72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16647 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone targets Enzyme (Prostacyclin synthase) DrugCentral uuid:5d71a7e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:5d71a7e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:5d71d6ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2036 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenbutazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5d71ff92-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenonium is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5d7224b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenonium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:5d724970-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyphenonium is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.84']} DrugCentral uuid:5d72722e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A7V8 biolink:molecularly_interacts_with DrugCentral:2041 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytetracycline targets Ribosomal protein (30S ribosomal protein S4) DrugCentral uuid:5d7296a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A7X3 biolink:molecularly_interacts_with DrugCentral:2041 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytetracycline targets Ribosomal protein (30S ribosomal protein S9) DrugCentral uuid:5d72bc3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:5d72e7f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:5d73117a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5d733a38-6b31-11ec-b3df-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin is agonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5d736350-6b31-11ec-b3df-0242ac110002 UniProtKB:P01178 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets Secreted (Oxytocin-neurophysin 1) DrugCentral uuid:5d7388d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5d73b1c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5d73da9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:2042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxytocin is agonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5d74042c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozagrel targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5d742cd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P49430 biolink:molecularly_interacts_with DrugCentral:2043 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozagrel targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5d745594-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5d747e52-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5d74a83c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:5d74d0fa-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Transporter (Bile salt export pump) DrugCentral uuid:5d74f576-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:5d7519de-6b31-11ec-b3df-0242ac110002 UniProtKB:P07437 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Structural (Tubulin beta chain) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d754382-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.621']} DrugCentral uuid:5d756d94-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.954']} DrugCentral uuid:5d759652-6b31-11ec-b3df-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.643']} DrugCentral uuid:5d75bf2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:5d75e8aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.794']} DrugCentral uuid:5d76117c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5d763a4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5d766442-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13509 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Structural (Tubulin beta-3 chain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:5d768d6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC29 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel targets Cytosolic other (Nucleotide-binding oligomerization domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5d76d4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d76d4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d76d4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d76d4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d76d4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d76d4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d76d4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d76d4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d76d4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paclitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5d775e92-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:2045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palmidrol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5d77876e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:2045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palmidrol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5d77b0f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:2045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palmidrol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5d77d9c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:2045 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palmidrol is agonist of GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5d780298-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palonosetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.5']} DrugCentral uuid:5d782f5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palonosetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.74']} DrugCentral uuid:5d782f5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palonosetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.74']} DrugCentral uuid:5d786620-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:2047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pamabrom targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:5d788f1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:2048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pamidronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:5d78b7f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:2048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pamidronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5d78e12c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07010 biolink:molecularly_interacts_with DrugCentral:2048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pamidronic acid targets Enzyme (Hypoxanthine-guanine phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5d790a08-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5d7932ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5d795bca-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.45']} DrugCentral uuid:5d798500-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5d79adbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q81VW8 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Dihydropteroate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.25']} DrugCentral uuid:5d79d6ae-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2049 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminobenzoic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5d79ff76-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WNC6 biolink:molecularly_interacts_with DrugCentral:2050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminosalicylic acid targets Kinase (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase) DrugCentral uuid:5d7a24ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:2050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminosalicylic acid targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['2.92']} DrugCentral uuid:5d7a5188-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminosalicylic acid is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:5d7a5188-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aminosalicylic acid is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:5d7a88c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:5d7a88c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:5d7a88c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:5d7acff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5d7acff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5d7b115e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5d7b115e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5d7b115e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5d7b115e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5d7b5eac-6b31-11ec-b3df-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:5d7b8328-6b31-11ec-b3df-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5d7babfa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5d7bd4cc-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5d7bfee8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5d7c27b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:5d7c5460-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:5d7c5460-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:5d7c83c2-6b31-11ec-b3df-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5d7cb068-6b31-11ec-b3df-0242ac110002 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d7cb068-6b31-11ec-b3df-0242ac110002 UniProtKB:P27112 biolink:molecularly_interacts_with DrugCentral:2054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pantoprazole targets Enzyme (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d7ce524-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5d7d0e00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5d7d3772-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:5d7d5bee-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5d7d84c0-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5d7dad92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5d7dda60-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.118']} DrugCentral uuid:5d7e0774-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.088']} DrugCentral uuid:5d7e32b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5d7e5c1a-6b31-11ec-b3df-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5d7e853c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5d7eae36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM07 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Protein-arginine deiminase type-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:5d7ed708-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5d7f005c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XSW7 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Cyclic nucleotide phosphodiesterase PDE3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5d7f2938-6b31-11ec-b3df-0242ac110002 UniProtKB:O77823 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Cyclic AMP-specific phosphodiesterase SSPDE4A1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d7f5200-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QYJ6 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:5d7f8284-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5d7f8284-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5d7f8284-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5d7fc8ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5d7fc8ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5d800510-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5d800510-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5d800510-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5d8046e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5d807036-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2056 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 papaverine targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5d80a09c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paramethadione is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:5d80a09c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paramethadione is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:5d80a09c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paramethadione is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:5d80dbb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.854']} DrugCentral uuid:5d810492-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:5d812d78-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5d8157ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5d818458-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5d81ad52-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5d81d642-6b31-11ec-b3df-0242ac110002 UniProtKB:P11884 biolink:molecularly_interacts_with DrugCentral:2065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pargyline targets Enzyme (Aldehyde dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:5d81ff78-6b31-11ec-b3df-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paricalcitol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5d822840-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5d825112-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.647']} DrugCentral uuid:5d8279ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.068']} DrugCentral uuid:5d82a34c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:5d82cc46-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.398']} DrugCentral uuid:5d82f522-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.52']} DrugCentral uuid:5d831df4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5d8348f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:5d8371dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.724']} DrugCentral uuid:5d839ac2-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5d83c39e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:5d83ecfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.051']} DrugCentral uuid:5d8415d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:5d843ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5d8467d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d8490b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5d84b984-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d84e242-6b31-11ec-b3df-0242ac110002 UniProtKB:P25098 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Kinase (Beta-adrenergic receptor kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:5d850cc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:5d853896-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:5d856294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5d858b5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.36']} DrugCentral uuid:5d85b4c4-6b31-11ec-b3df-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5d85dda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:5d860690-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5d863016-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99571 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Ion channel (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5d8660fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5d8660fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5d8660fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5d86a96a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5d86a96a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5d86a96a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5d86ecf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:5d8715d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:5d873e98-6b31-11ec-b3df-0242ac110002 UniProtKB:P21146 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Kinase (Beta-adrenergic receptor kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5d876774-6b31-11ec-b3df-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:2068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paroxetine targets Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:5d8790aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES4 biolink:molecularly_interacts_with DrugCentral:2071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pefloxacin targets Enzyme (DNA gyrase subunit A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.785']} DrugCentral uuid:5d87b972-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pefloxacin targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.097']} DrugCentral uuid:5d87e24e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pefloxacin targets Enzyme (DNA gyrase subunit B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.785']} DrugCentral uuid:5d880b16-6b31-11ec-b3df-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed is inhibitor of Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.468']} DrugCentral uuid:5d88346a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.181']} DrugCentral uuid:5d885d28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Folylpolyglutamate synthase, mitochondrial) DrugCentral uuid:5d8881a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5d88aa76-6b31-11ec-b3df-0242ac110002 UniProtKB:P34896 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Serine hydroxymethyltransferase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5d88d64a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14207 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Membrane receptor (Folate receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5d88ff26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:5d8928f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:5d89523c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A884 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5d897afa-6b31-11ec-b3df-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5d89a462-6b31-11ec-b3df-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5d89cd48-6b31-11ec-b3df-0242ac110002 UniProtKB:P45352 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5d89f6a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5d8a1f82-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5d8a485e-6b31-11ec-b3df-0242ac110002 UniProtKB:C3SWJ7 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5d8a7130-6b31-11ec-b3df-0242ac110002 UniProtKB:E2QDN0 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Enzyme (Thymidylate synthase (EC 2.1.1.45) (TS) (TSase)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:5d8a9b56-6b31-11ec-b3df-0242ac110002 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.86']} DrugCentral uuid:5d8ac41e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:5d8aecf0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q64737 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed is inhibitor of Enzyme (Trifunctional purine biosynthetic protein adenosine-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:5d8b1608-6b31-11ec-b3df-0242ac110002 UniProtKB:P22102 biolink:molecularly_interacts_with DrugCentral:2073 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemetrexed is inhibitor of Enzyme (Trifunctional purine biosynthetic protein adenosine-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5d8b3f66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2075 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemoline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:5d8b684c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5d8b9150-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5d8bba72-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5d8be358-6b31-11ec-b3df-0242ac110002 UniProtKB:P02763 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol targets Secreted (Alpha-1-acid glycoprotein 1) DrugCentral uuid:5d8c07ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penbutolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:5d8c30a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2079 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:5d8c5680-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:2079 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penciclovir targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5d8c8150-6b31-11ec-b3df-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:2079 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penciclovir targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:5d8caa18-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5d8cd312-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.83']} DrugCentral uuid:5d8cfc5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5d8d2538-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.45']} DrugCentral uuid:5d8d4f22-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5d8d7808-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5d8da13e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.682']} DrugCentral uuid:5d8dcb46-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5d8df436-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5d8e1d1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:5d8e4954-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5d8e7438-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5d8e9d1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5d8ec5fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5d8eef4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:5d8f182a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:5d8f4110-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5d8f6a6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5d8f9368-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5d8fbc3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d8fe52a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5d901e5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5d901e5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5d901e5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5d901e5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5d901e5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penfluridol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5d9076b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P44514 biolink:molecularly_interacts_with DrugCentral:2081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 penicillamine targets Enzyme (Succinyl-diaminopimelate desuccinylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5d909fd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5d90c472-6b31-11ec-b3df-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5d90ed94-6b31-11ec-b3df-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5d912dfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d912dfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d912dfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d912dfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d912dfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d912dfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d912dfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d9190fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylpenicillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5d91b9d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5d91f82e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d91f82e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d91f82e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d91f82e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d91f82e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d91f82e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d91f82e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxymethylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5d925ba2-6b31-11ec-b3df-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:2088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentagastrin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:5d9284f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:2088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentagastrin targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5d92adc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:2088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentagastrin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:5d92d7d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:2088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentagastrin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5d930098-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.287']} DrugCentral uuid:5d9329e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5d9352aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.658']} DrugCentral uuid:5d937b90-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:5d93a480-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.765']} DrugCentral uuid:5d93ce74-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.867']} DrugCentral uuid:5d93f750-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.295']} DrugCentral uuid:5d942036-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.658']} DrugCentral uuid:5d944a84-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.683']} DrugCentral uuid:5d94736a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5d949c3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.309']} DrugCentral uuid:5d94c536-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.101']} DrugCentral uuid:5d94ee4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5d95172a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5d953ffc-6b31-11ec-b3df-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5d9568ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:5d9592c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P04271 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Cytosolic other (Protein S100-B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5d95bbbc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:5d95e48e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5d960d56-6b31-11ec-b3df-0242ac110002 UniProtKB:P19801 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Amiloride-sensitive amine oxidase [copper-containing]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:5d9636f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.272']} DrugCentral uuid:5d965fc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5d968894-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5d96b15c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5d96dab0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5d970382-6b31-11ec-b3df-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5d9742fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5d9742fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5d9742fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5d9742fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5d9742fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5d9742fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5d9742fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5d97c222-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:5d97c222-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:5d97f814-6b31-11ec-b3df-0242ac110002 UniProtKB:P21673 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Spermidine/spermine N(1)-acetyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5d9820f0-6b31-11ec-b3df-0242ac110002 UniProtKB:O75365 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Protein-tyrosine phosphatase 4A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:5d9849cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08001 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Acrosin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5d98729e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04631 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Unclassified (Protein S100-B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.36']} DrugCentral uuid:5d989bca-6b31-11ec-b3df-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5d98c4b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5d98edf0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12974 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Protein tyrosine phosphatase type IVA 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5d9917e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q93096 biolink:molecularly_interacts_with DrugCentral:2090 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentamidine targets Enzyme (Protein tyrosine phosphatase type IVA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5d994232-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:5d996afa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.553']} DrugCentral uuid:5d999b7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:5d999b7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:5d999b7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9a1586-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5d9afa46-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5d9afa46-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5d9afa46-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentobarbital targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5d9b3bfa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZZ6 biolink:molecularly_interacts_with DrugCentral:2096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentolonium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-10) DrugCentral uuid:5d9b6472-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentolonium is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:5d9b6472-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentolonium is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:5d9b935c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00813 biolink:molecularly_interacts_with DrugCentral:2098 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentostatin is inhibitor of Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.8']} DrugCentral uuid:5d9bbcf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P56658 biolink:molecularly_interacts_with DrugCentral:2098 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentostatin targets Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:5d9be5e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:2099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxifylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5d9c0ee0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:2099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxifylline is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) DrugCentral uuid:5d9c3366-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxifylline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:5d9c5c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentoxifylline is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) DrugCentral uuid:5d9c8118-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5d9ca9fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5d9cd38e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5d9cfc6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5d9d251e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5d9d4dd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5d9d773a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:5d9da106-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:5d9dcafa-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5d9df3e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5d9e1cee-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:5d9e45e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5d9e6e9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5d9e9778-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5d9ec1d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5d9eeaa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:5d9f143c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:5d9f3d22-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:5d9f66b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.838']} DrugCentral uuid:5d9f8fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.398']} DrugCentral uuid:5d9fb87e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:5d9fe1c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5da00aa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5da03376-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5da05c5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:5da086a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:5da0b062-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5da0e0fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:5da0e0fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:5da0e0fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:5da12646-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5da12646-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5da16a34-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:5da16a34-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:5da16a34-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:5da16a34-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:5da16a34-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.51']} DrugCentral uuid:5da1c89e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:5da1c89e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide targets GPCR (Cerebral cortex alpha adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.39']} DrugCentral uuid:5da1fd64-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5da22654-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pergolide is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5da24fda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.962']} DrugCentral uuid:5da27956-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5da2a228-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.486']} DrugCentral uuid:5da2cb0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.185']} DrugCentral uuid:5da2f48a-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5da31d66-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5da34638-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.105']} DrugCentral uuid:5da36f1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.027']} DrugCentral uuid:5da3984a-6b31-11ec-b3df-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:5da3bcc6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.356']} DrugCentral uuid:5da3e6d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) DrugCentral uuid:5da40b54-6b31-11ec-b3df-0242ac110002 UniProtKB:P50416 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine O-palmitoyltransferase 1, liver isoform) DrugCentral uuid:5da43156-6b31-11ec-b3df-0242ac110002 UniProtKB:P23786 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine O-palmitoyltransferase 2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:5da45b9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.828']} DrugCentral uuid:5da48462-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.391']} DrugCentral uuid:5da4ad5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63704 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine O-palmitoyltransferase 1, muscle isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5da4de6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5da4de6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5da4de6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5da5207a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18886 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine palmitoyltransferase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5da549d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P32198 biolink:molecularly_interacts_with DrugCentral:2106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perhexiline targets Enzyme (Carnitine palmitoyltransferase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:5da57318-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 periciazine is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5da59bf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 periciazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5da5c4d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 periciazine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5da5edb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2107 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 periciazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5da619e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2108 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perindopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5da642b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.222']} DrugCentral uuid:5da66b9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.704']} DrugCentral uuid:5da694e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.824']} DrugCentral uuid:5da6bdd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5da6e694-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5da70f66-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:5da738b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perlapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5da7618c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perospirone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5da78a5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perospirone is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:5da7b358-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perospirone is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:5da7de0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perospirone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:5da8084e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.32']} DrugCentral uuid:5da83198-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5da85a92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.462']} DrugCentral uuid:5da8840e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5da8acf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.252']} DrugCentral uuid:5da8d6ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.879']} DrugCentral uuid:5da8ff88-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5da928c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:5da951a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5da97a6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:5da9a438-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.521']} DrugCentral uuid:5da9cd8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.088']} DrugCentral uuid:5da9f65e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.733']} DrugCentral uuid:5daa1f26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.481']} DrugCentral uuid:5daa4898-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5daa7282-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.588']} DrugCentral uuid:5daa9b7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5daac426-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5daaed98-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perphenazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5dab1656-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacemide is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:5dab3adc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacetin targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:5dab5f62-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5dab89f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5dabb2e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5dabdbe0-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5dac04bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:2119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:5dac503e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5dac503e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5dac503e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5dac503e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5dac503e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5dac503e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5dac503e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5dac503e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5dac503e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5dac503e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5dacd3c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P83512 biolink:molecularly_interacts_with DrugCentral:2120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenazopyridine targets Enzyme (Snake venom metalloproteinase Bap1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:5dacfd0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5dad2608-6b31-11ec-b3df-0242ac110002 UniProtKB:P42785 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Enzyme (Lysosomal Pro-X carboxypeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:5dad5006-6b31-11ec-b3df-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:5dad7978-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5dada254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00961 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate receptor ionotropic, NMDA 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5dadcb30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5dadf498-6b31-11ec-b3df-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5dae3458-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5dae3458-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5dae3458-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5dae3458-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5dae3458-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5dae3458-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5dae3458-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5daebbe4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5daebbe4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5daebbe4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5daebbe4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5daebbe4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5daebbe4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5daebbe4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5daf33e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5daf33e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5daf6c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5daf6c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5dafb09e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5dafb09e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5dafb09e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5dafb09e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5dafb09e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2121 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phencyclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5db00a08-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phendimetrazine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:5db02e7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phendimetrazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5db0576a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phendimetrazine is inhibitor of Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:5db07c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5db0a512-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.076']} DrugCentral uuid:5db0ce02-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5db0f7c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine is inhibitor of Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5db1229e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:5db14b84-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5db17488-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.836']} DrugCentral uuid:5db19dd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:5db1c6ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16853 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Membrane primary amine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5db1ef76-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5db21834-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:5db2416a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5db26a3c-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:5db29444-6b31-11ec-b3df-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenelzine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5db2bce4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y478 biolink:molecularly_interacts_with DrugCentral:2126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenformin targets Kinase (5'-AMP-activated protein kinase subunit beta-1) DrugCentral uuid:5db2e37c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2129 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenindamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5db30c6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:2130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenindione is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) DrugCentral uuid:5db330e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenindione targets Enzyme (Prothrombin) DrugCentral uuid:5db3555a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:2130 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5db37ed6-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2131 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniprazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:5db3a348-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2131 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniprazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:5db3c7e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5db3ec5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.378']} DrugCentral uuid:5db41d78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:5db41d78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:5db41d78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2132 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pheniramine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:5db45e46-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenmetrazine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.298']} DrugCentral uuid:5db48718-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenmetrazine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.883']} DrugCentral uuid:5db4b1fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenmetrazine targets Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:5db4d696-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:5db4fc2a-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:5db52858-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5db52858-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5db52858-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5db56a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5db56a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5db56a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenobarbital targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5db5aac6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:2135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5db5d398-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A884 biolink:molecularly_interacts_with DrugCentral:2135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5db5fd00-6b31-11ec-b3df-0242ac110002 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:2135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5db626d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q834R3 biolink:molecularly_interacts_with DrugCentral:2135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenolphthalein targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5db64fda-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5db6797e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:5db6a26e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.456']} DrugCentral uuid:5db6cb5e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5db7033a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5db7033a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5db7033a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5db7033a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5db7033a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5db76460-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5db76460-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5db76460-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5db7add0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:5db7add0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:5db7add0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2136 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenoxybenzamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:5db7ee80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenprocoumon targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5db81752-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6TEK4 biolink:molecularly_interacts_with DrugCentral:2138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenprocoumon targets Unclassified (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5db84042-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6TEK4 biolink:molecularly_interacts_with DrugCentral:2138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenprocoumon targets Unclassified (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5db86aa4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:2138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenprocoumon is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.745']} DrugCentral uuid:5db89b32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phensuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:5db89b32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phensuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:5db89b32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phensuximide is blocker of Ion channel (Voltage-gated T-type calcium channel) DrugCentral uuid:5db8d520-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentermine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:5db8fa46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentermine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.801']} DrugCentral uuid:5db92430-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:5db94d2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5db975fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.784']} DrugCentral uuid:5db99f46-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.667']} DrugCentral uuid:5db9c80e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.609']} DrugCentral uuid:5db9f0ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.616']} DrugCentral uuid:5dba19bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.684']} DrugCentral uuid:5dba43a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:5dba6dc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:5dba9694-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:5dbac02e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:5dbae914-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5dbb11fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.71']} DrugCentral uuid:5dbb3afe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:5dbb6452-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.94']} DrugCentral uuid:5dbb8d38-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:5dbbb600-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5dbbdefa-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:5dbc09fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:5dbc32d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:5dbc5bb4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5dbc849a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.03']} DrugCentral uuid:5dbcae16-6b31-11ec-b3df-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5dbcdea4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5dbcdea4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5dbcdea4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5dbd285a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5dbd285a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5dbd285a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phentolamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5dbd939e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:5dbdbd60-6b31-11ec-b3df-0242ac110002 UniProtKB:O08532 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5dbde89e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63016 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Transporter (L-type amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:5dbe1184-6b31-11ec-b3df-0242ac110002 UniProtKB:P19111 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Enzyme (Intestinal alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5dbe3a6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6DWJ6 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine is agonist of GPCR (Probable G-protein coupled receptor 139) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:5dbe640e-6b31-11ec-b3df-0242ac110002 UniProtKB:P09923 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Enzyme (Intestinal-type alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5dbe8dee-6b31-11ec-b3df-0242ac110002 UniProtKB:P98170 biolink:molecularly_interacts_with DrugCentral:2144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylalanine targets Unclassified (E3 ubiquitin-protein ligase XIAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5dbeb6e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5dbedfb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:5dbf08c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16647 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Prostacyclin synthase) DrugCentral uuid:5dbf2d4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:5dbf5620-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8SPQ9 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Cyclooxygenase 2; Prostaglandin G/H synthase-2; Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5dbf82d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5dbf82d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5dbfb980-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2145 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylbutazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:5dbfe270-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5dc00b74-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5dc03450-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5dc05dea-6b31-11ec-b3df-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5dc086bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5dc0afa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5dc0e2e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5dc0e2e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5dc0e2e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5dc12b80-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5dc12b80-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5dc12b80-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5dc174aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5dc174aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5dc174aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5dc1b596-6b31-11ec-b3df-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:2146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylephrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5dc1de68-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:5dc20744-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:5dc22c74-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:5dc25546-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.155']} DrugCentral uuid:5dc27e22-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine is agonist of GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5dc2a29e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.398']} DrugCentral uuid:5dc2cbe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.171']} DrugCentral uuid:5dc2f4ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.577']} DrugCentral uuid:5dc31daa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.166']} DrugCentral uuid:5dc34780-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:5dc3728c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:5dc39b90-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5dc3c476-6b31-11ec-b3df-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylpropanolamine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5dc3ede8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5dc416ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:5dc440ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5dc46994-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:5dc492fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenyltoloxamine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5dc4b78c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:5dc4dc26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5dc5014c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:5dc526ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5dc54fb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:5dc57474-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:5dc59d50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:5dc5c28a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:5dc5e71a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5dc61794-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5dc61794-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5dc61794-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenytoin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5dc658c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:2153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phloroglucinol targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5dc68576-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5dc68576-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5dc6c3ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5dc6c3ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5dc6c3ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxagrelate targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5dc7069a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5dc72fb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.37']} DrugCentral uuid:5dc7588e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5dc7817e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5dc7aadc-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.17']} DrugCentral uuid:5dc7d49e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:5dc7fd70-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.17']} DrugCentral uuid:5dc82692-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.47']} DrugCentral uuid:5dc84f78-6b31-11ec-b3df-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5dc8785e-6b31-11ec-b3df-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:5dc8a126-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5dc8cab6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5dc8f37e-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:5dc91c64-6b31-11ec-b3df-0242ac110002 UniProtKB:P36196 biolink:molecularly_interacts_with DrugCentral:2159 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 physostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5dc94540-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin is blocker of Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5dc96ed0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin is blocker of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5dc997ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin is blocker of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5dc9c0a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin is blocker of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dca2294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotoxin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5dcb0114-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotin targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5dcb2a04-6b31-11ec-b3df-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:2163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotin is blocker of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5dcb539e-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:2163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotin is blocker of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5dcb7d10-6b31-11ec-b3df-0242ac110002 UniProtKB:O75311 biolink:molecularly_interacts_with DrugCentral:2163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picrotin targets Ion channel (Glycine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5dcba5d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:5dcbcbc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piketoprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:5dcbf0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:5dcc19a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5dcc4272-6b31-11ec-b3df-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5dcc6b44-6b31-11ec-b3df-0242ac110002 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5dcca3fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:5dcca3fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:5dcca3fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:5dcca3fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:5dcca3fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:5dccfc9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5dcd2610-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:5dcd4ee2-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:5dcd77b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5dcda07c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilocarpine is agonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5dcdc9b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilsicainide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:5dcdf3a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:2167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pilsicainide is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.377']} DrugCentral uuid:5dce1c78-6b31-11ec-b3df-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus targets Cytokine (Interleukin-5) DrugCentral uuid:5dce4176-6b31-11ec-b3df-0242ac110002 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus targets Cytokine (Interferon gamma) DrugCentral uuid:5dce6660-6b31-11ec-b3df-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5dce8f3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P60568 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus targets Cytokine (Interleukin-2) DrugCentral uuid:5dceb3b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P48454 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform) DrugCentral uuid:5dced852-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62658 biolink:molecularly_interacts_with DrugCentral:2168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimecrolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5dcf0188-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimethixene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5dcf2a96-6b31-11ec-b3df-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimethixene targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:5dcf5368-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WTS6 biolink:molecularly_interacts_with DrugCentral:2169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimethixene targets Enzyme (Histone-lysine N-methyltransferase SETD7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5dcf7cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:2171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimobendan targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5dcfa980-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimobendan is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5dcfa980-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimobendan is inhibitor of Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5dcfde50-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5dd0072c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.862']} DrugCentral uuid:5dd03210-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.798']} DrugCentral uuid:5dd05ae2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.842']} DrugCentral uuid:5dd083be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:5dd0ac86-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.538']} DrugCentral uuid:5dd0d5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.63']} DrugCentral uuid:5dd0fe84-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.559']} DrugCentral uuid:5dd1274c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.058']} DrugCentral uuid:5dd150a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.149']} DrugCentral uuid:5dd17972-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.301']} DrugCentral uuid:5dd1a23a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.704']} DrugCentral uuid:5dd1cb84-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.086']} DrugCentral uuid:5dd1f744-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:5dd221ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:5dd24aaa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5dd27372-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.709']} DrugCentral uuid:5dd29cd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:5dd2c5a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.424']} DrugCentral uuid:5dd2ee88-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:5dd3176e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5dd3409a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5dd36958-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5dd3922a-6b31-11ec-b3df-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5dd3c3ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:5dd3c3ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:5dd3c3ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:5dd4055c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5dd42e24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0X4 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1I) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5dd4570a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:5dd4804a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16322 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5dd4a930-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5dd4d22a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5dd4fb56-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5dd5243c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5dd54e30-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:5dd5863e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5dd5863e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5dd5863e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5dd5863e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5dd5863e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5dd5e1ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O94782 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide targets Enzyme (Ubiquitin carboxyl-terminal hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5dd60b04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EQ60 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5dd6344e-6b31-11ec-b3df-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:5dd65d34-6b31-11ec-b3df-0242ac110002 UniProtKB:O54898 biolink:molecularly_interacts_with DrugCentral:2172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimozide is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5dd68606-6b31-11ec-b3df-0242ac110002 UniProtKB:O60706 biolink:molecularly_interacts_with DrugCentral:2173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pinacidil targets Ion channel (ATP-binding cassette sub-family C member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:5dd6ae9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12791 biolink:molecularly_interacts_with DrugCentral:2173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pinacidil targets Ion channel (Calcium-activated potassium channel subunit alpha-1) DrugCentral uuid:5dd6d85e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pinacidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5dd6d85e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pinacidil is opener of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5dd70d4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol is partial agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5dd73646-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol is partial agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5dd75f2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5dd78b5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5dd7b436-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5dd7dd30-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.27']} DrugCentral uuid:5dd8067a-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.78']} DrugCentral uuid:5dd83082-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5dd8595e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.209']} DrugCentral uuid:5dd8824e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5dd8ab8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5dd8e05e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5dd8e05e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5dd8e05e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5dd8e05e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5dd935cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5dd935cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5dd935cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pindolol targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5dd977bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.943']} DrugCentral uuid:5dd9a070-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5dd9c942-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5dd9f278-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.455']} DrugCentral uuid:5dda1b40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:5dda4426-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:5dda6ce4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.879']} DrugCentral uuid:5dda9610-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5ddabf00-6b31-11ec-b3df-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transcription factor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:5ddae7d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P37238 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transcription factor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5ddb10a4-6b31-11ec-b3df-0242ac110002 UniProtKB:O88275 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transcription factor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5ddb3dc2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5ddb66da-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5ddb8fca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5ddbb914-6b31-11ec-b3df-0242ac110002 UniProtKB:B0K020 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5ddbe1d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:5ddc0aae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N5K1 biolink:molecularly_interacts_with DrugCentral:2179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pioglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5ddc3380-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:5ddc5cd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.87']} DrugCentral uuid:5ddc859c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:5ddcaf72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:5ddcd858-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.461']} DrugCentral uuid:5ddd03fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.351']} DrugCentral uuid:5ddd2cd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.992']} DrugCentral uuid:5ddd55bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.256']} DrugCentral uuid:5ddd7e98-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.509']} DrugCentral uuid:5ddda800-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:5dddd0dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:5dddf9c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.105']} DrugCentral uuid:5dde2302-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.799']} DrugCentral uuid:5dde4bf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.939']} DrugCentral uuid:5dde753c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:5dde9f58-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.189']} DrugCentral uuid:5ddec938-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5ddef20a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:5ddf1adc-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.848']} DrugCentral uuid:5ddf43cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.864']} DrugCentral uuid:5ddf6d2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.429']} DrugCentral uuid:5ddf961a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:5ddfbece-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:5ddfe7a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5de010cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5de039b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:5de0627a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.066']} DrugCentral uuid:5de08b60-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5de0b8d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5de0e1b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.324']} DrugCentral uuid:5de10aae-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.644']} DrugCentral uuid:5de13402-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:5de15cde-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.602']} DrugCentral uuid:5de185e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5de1aebe-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5de1d808-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5de200e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.538']} DrugCentral uuid:5de229ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5de2527e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipamperone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5de2823a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:5de2823a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:5de2b8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:5de2b8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:5de2b8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:5de2f60c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:5de2f60c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:5de32960-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:5de32960-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:5de3584a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5de37cbc-6b31-11ec-b3df-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5de3a5fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5de3e594-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5de3e594-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5de3e594-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5de3e594-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5de3e594-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5de3e594-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5de3e594-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperacillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5de44c32-6b31-11ec-b3df-0242ac110002 UniProtKB:O18276 biolink:molecularly_interacts_with DrugCentral:2188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperazine targets Ion channel (Gamma-aminobutyric acid receptor subunit beta) DrugCentral uuid:5de470cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipotiazine palmitate is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.699']} DrugCentral uuid:5de499c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2193 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pipotiazine palmitate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.553']} DrugCentral uuid:5de4c2ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2199 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirbuterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:5de4e7be-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:5de510c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:5de5399e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:5de562e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:5de58c32-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5de5b50e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5de5ddf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5de60766-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:5de631f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5de65ac2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WMX0 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:5de683bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5de6ad10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VH26 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5de6d5ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5de70e22-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5de70e22-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5de70e22-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5de70e22-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5de70e22-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5de7765a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5de7765a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5de7765a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5de7765a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5de7765a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2200 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirenzepine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5de7d028-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:2201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piretanide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5de7fbd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P55011 biolink:molecularly_interacts_with DrugCentral:2201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piretanide is inhibitor of Transporter (Solute carrier family 12 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5de8251e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5de84e0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5de876ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5de8a048-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5de8c924-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:5de8f21e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5de91afa-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5de9443a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5de96d16-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5de995e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5de9c04a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piribedil is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5de9e94e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5dea1216-6b31-11ec-b3df-0242ac110002 UniProtKB:P28347 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5dea3c50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15561 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:5dea65a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15562 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:5dea8e94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99594 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole targets Transcription factor (Transcriptional enhancer factor TEF-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:5deab78e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2206 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirlindole is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:5deae060-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirmenol targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5deb055e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5deb2e4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:5deb5716-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5deb84c0-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5deb84c0-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5debc0fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5debc0fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piroxicam targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5debf5c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirprofen targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:5dec1a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pirprofen targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:5dec3f28-6b31-11ec-b3df-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitavastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.168']} DrugCentral uuid:5dec68a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitavastatin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.88']} DrugCentral uuid:5dec918a-6b31-11ec-b3df-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitavastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5decba52-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:5dece392-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5ded0c78-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:5ded3568-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5ded5e44-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5ded8978-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5dedb240-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pizotifen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5deddb30-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:2228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polythiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['9.09']} DrugCentral uuid:5dee0470-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralidoxime is activator of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5dee2d4c-6b31-11ec-b3df-0242ac110002 UniProtKB:O08725 biolink:molecularly_interacts_with DrugCentral:2232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralmorelin is agonist of GPCR (Growth hormone secretagogue receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5dee563c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92847 biolink:molecularly_interacts_with DrugCentral:2232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralmorelin is agonist of GPCR (Growth hormone secretagogue receptor type 1) DrugCentral uuid:5dee7ac2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:5deea40c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5deeccac-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.121']} DrugCentral uuid:5deef59c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:5def1e6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:5def48a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.925']} DrugCentral uuid:5def727e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5def9b64-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.668']} DrugCentral uuid:5defc40e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.571']} DrugCentral uuid:5defed76-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.455']} DrugCentral uuid:5df0165c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:5df03f38-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.282']} DrugCentral uuid:5df06832-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:5df091a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:5df0bbc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5df0e4a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramipexole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:5df1130e-6b31-11ec-b3df-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:5df1130e-6b31-11ec-b3df-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:5df14f36-6b31-11ec-b3df-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:5df14f36-6b31-11ec-b3df-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.45']} DrugCentral uuid:5df187e4-6b31-11ec-b3df-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5df187e4-6b31-11ec-b3df-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramlintide is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5df1bd22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5df1e5f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5df20ed0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5df237ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5df26100-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13304 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5df28a68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast targets Nuclear other (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5df2b34e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:2237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:5df2dc20-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2238 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranoprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5df3063c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2238 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pranoprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5df33008-6b31-11ec-b3df-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pravastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5df358da-6b31-11ec-b3df-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pravastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:5df38238-6b31-11ec-b3df-0242ac110002 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:2239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pravastatin targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5df3b2da-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5df3b2da-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5df3b2da-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5df3ebf6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 praziquantel targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:5df414be-6b31-11ec-b3df-0242ac110002 UniProtKB:P08515 biolink:molecularly_interacts_with DrugCentral:2241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 praziquantel targets Enzyme (Glutathione S-transferase class-mu 26 kDa isozyme) DrugCentral uuid:5df439d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95US7 biolink:molecularly_interacts_with DrugCentral:2241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 praziquantel is blocker of Ion channel (High voltage-activated calcium channel beta subunit CavB1) DrugCentral uuid:5df45e6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q962H3 biolink:molecularly_interacts_with DrugCentral:2241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 praziquantel is blocker of Ion channel (High voltage-activated calcium channel beta subunit CavB2) DrugCentral uuid:5df482e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2243 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednicarbate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5df4a7f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5df4d412-6b31-11ec-b3df-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Cytosolic other (Annexin A1) DrugCentral uuid:5df4f8b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:5df521a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5df54a82-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5df573c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5df59c8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Cytokine (Interleukin-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:5df5c55c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5df5eec4-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:5df61796-6b31-11ec-b3df-0242ac110002 UniProtKB:P15104 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Enzyme (Glutamine synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:5df6405e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:5df66926-6b31-11ec-b3df-0242ac110002 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:5df692e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P78536 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Unclassified (Disintegrin and metalloproteinase domain-containing protein 17) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:5df6bb9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5df6e4a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5df70bc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.28']} DrugCentral uuid:5df734fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:5df75dd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5df786d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5df7b01a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5df7d9a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Cytokine (Interleukin-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.38']} DrugCentral uuid:5df8025e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5df82b4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:5df8542a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15104 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Enzyme (Glutamine synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5df87fea-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:5df8a89e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:5df8d1e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P78536 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Unclassified (Disintegrin and metalloproteinase domain-containing protein 17) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:5df8faec-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone tebutate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5df923c8-6b31-11ec-b3df-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisone targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.772']} DrugCentral uuid:5df94ca4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5df97558-6b31-11ec-b3df-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisone targets Cytosolic other (Annexin A1) DrugCentral uuid:5df99a42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:2255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregabalin targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.801']} DrugCentral uuid:5df9c31e-6b31-11ec-b3df-0242ac110002 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:2255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregabalin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:5df9ec0e-6b31-11ec-b3df-0242ac110002 UniProtKB:O77773 biolink:molecularly_interacts_with DrugCentral:2255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregabalin targets Ion channel (Uncharacterized protein; Voltage-dependent calcium channel alpha-2 delta subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:5dfa14ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY47 biolink:molecularly_interacts_with DrugCentral:2255 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregabalin is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:5dfa3f7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregnenolone succinate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:5dfa68dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:2256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregnenolone succinate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5dfa91c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:2256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pregnenolone succinate targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:5dfaba94-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenalterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5dfae4d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenalterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.97']} DrugCentral uuid:5dfb1566-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5dfb1566-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5dfb1566-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5dfb5dc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5dfb5dc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5dfb5dc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5dfb9f22-6b31-11ec-b3df-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:2261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prenylamine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5dfbc7fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:5dfbf0da-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5dfc1c36-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.194']} DrugCentral uuid:5dfc45bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:5dfc6e98-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pridinol targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.799']} DrugCentral uuid:5dfc9f62-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prilocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:5dfc9f62-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prilocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:5dfc9f62-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prilocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:5dfce120-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.668']} DrugCentral uuid:5dfd0a06-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.075']} DrugCentral uuid:5dfd340e-6b31-11ec-b3df-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:5dfd5916-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:5dfd81ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5dfdaaa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.739']} DrugCentral uuid:5dfdd382-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:5dfdff2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:5dfe23dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:5dfe4dbc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5dfe7684-6b31-11ec-b3df-0242ac110002 UniProtKB:P35869 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Transcription factor (Aryl hydrocarbon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.328']} DrugCentral uuid:5dfe9fce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:5dfec8b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5dfef190-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primaquine targets Unclassified (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5dff2296-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primidone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5dff2296-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primidone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5dff2296-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primidone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5dff5be4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCF6 biolink:molecularly_interacts_with DrugCentral:2267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 primidone is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5dff84a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5dffad7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5dffdac4-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5e0003be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid is inhibitor of Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5e002c90-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid is inhibitor of Transporter (Solute carrier family 22 member 8) DrugCentral uuid:5e005184-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSA0 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid is inhibitor of Transporter (Solute carrier family 22 member 11) DrugCentral uuid:5e007600-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5e009ed2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5e00c7ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5e00f0f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HAW7 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid targets Enzyme (UDP-glucuronosyltransferase 1-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.02']} DrugCentral uuid:5e0119f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WUD2 biolink:molecularly_interacts_with DrugCentral:2268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probenecid is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5e0142ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.686']} DrugCentral uuid:5e016b8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e01959e-6b31-11ec-b3df-0242ac110002 UniProtKB:O95477 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol is inhibitor of Transporter (ATP-binding cassette sub-family A member 1) DrugCentral uuid:5e01ba74-6b31-11ec-b3df-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5e01e436-6b31-11ec-b3df-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:2269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 probucol targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:5e020d12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.86']} DrugCentral uuid:5e02371a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.812']} DrugCentral uuid:5e026000-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5e0288e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P26358 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (DNA (cytosine-5)-methyltransferase 1) DrugCentral uuid:5e02ad6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6K1 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (DNA (cytosine-5)-methyltransferase 3A) DrugCentral uuid:5e02d22e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBC3 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (DNA (cytosine-5)-methyltransferase 3B) DrugCentral uuid:5e02f6aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5e0341a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5e0341a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5e0341a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5e0341a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5e0341a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5e0341a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5e0341a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5e0341a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5e0341a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5e0341a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procainamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5e03cb34-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.569']} DrugCentral uuid:5e03f47e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.529']} DrugCentral uuid:5e041dc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:5e04423a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21817 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Ryanodine receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.222']} DrugCentral uuid:5e0472aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.342']} DrugCentral uuid:5e0472aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.342']} DrugCentral uuid:5e0472aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaine targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.342']} DrugCentral uuid:5e04b490-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:5e04dd4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2273 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procaterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:5e050634-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.712']} DrugCentral uuid:5e052fe2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.108']} DrugCentral uuid:5e055a30-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.764']} DrugCentral uuid:5e058406-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.201']} DrugCentral uuid:5e05ad0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:5e05d64a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5e05ff26-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.207']} DrugCentral uuid:5e062816-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.402']} DrugCentral uuid:5e0650f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.229']} DrugCentral uuid:5e067a3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:5e06a318-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.187']} DrugCentral uuid:5e06cbf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.914']} DrugCentral uuid:5e06f4da-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.907']} DrugCentral uuid:5e0720c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.622']} DrugCentral uuid:5e074cbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.324']} DrugCentral uuid:5e0776bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.611']} DrugCentral uuid:5e079f8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.723']} DrugCentral uuid:5e07c8ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.613']} DrugCentral uuid:5e07f1be-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.956']} DrugCentral uuid:5e081a90-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.493']} DrugCentral uuid:5e0843e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:5e086cb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.801']} DrugCentral uuid:5e08960a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:5e08bef0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:5e08e984-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:5e09126a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:5e093b46-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:5e09654e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5e09906e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.245']} DrugCentral uuid:5e09b94a-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5e09e212-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:5e0a0af8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.919']} DrugCentral uuid:5e0a3442-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.381']} DrugCentral uuid:5e0a5d14-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:5e0a85c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:5e0aafc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prochlorperazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5e0ad9a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.337']} DrugCentral uuid:5e0b0278-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:5e0b2b54-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.907']} DrugCentral uuid:5e0b5494-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:5e0b7d5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:5e0ba62e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5e0be5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5e0be5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5e0be5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5e0be5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5e0be5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5e0be5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5e0be5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 procyclidine targets Ion channel (Glutamate [NMDA] receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5e0c5e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.398']} DrugCentral uuid:5e0c5e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.398']} DrugCentral uuid:5e0c5e02-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.398']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0cd9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0df064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progabide targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e0ed0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.174']} DrugCentral uuid:5e0efa22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5e0f2308-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.32']} DrugCentral uuid:5e0f4bd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5e0f74ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:5e0f9dce-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:5e0fc24a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:5e0febc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['9.876']} DrugCentral uuid:5e10147a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:5e103ee6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.94']} DrugCentral uuid:5e1067cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35610 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Enzyme (Sterol O-acyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5e10909e-6b31-11ec-b3df-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5e10b984-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:5e10e2d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:5e110bbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.441']} DrugCentral uuid:5e11349a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5e115d76-6b31-11ec-b3df-0242ac110002 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:5e1186c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06186 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.98']} DrugCentral uuid:5e11afb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5e11d97c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5e1207bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e1207bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e1240ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:5e1240ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.41']} DrugCentral uuid:5e1275c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NEC5 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:5e129f06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96P56 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:5e12c7f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86XQ3 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:5e12f0c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7RTX7 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is activator of Ion channel (Cation channel sperm-associated protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:5e131ad0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone is blocker of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5e134474-6b31-11ec-b3df-0242ac110002 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:2279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 progesterone targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e136d64-6b31-11ec-b3df-0242ac110002 UniProtKB:P25102 biolink:molecularly_interacts_with DrugCentral:2281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proglumide targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['2.6']} DrugCentral uuid:5e13962c-6b31-11ec-b3df-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:2281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proglumide is antagonist of GPCR (Gastrin/cholecystokinin type B receptor) DrugCentral uuid:5e13babc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0IJY2 biolink:molecularly_interacts_with DrugCentral:2282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proguanil targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) DrugCentral uuid:5e13e082-6b31-11ec-b3df-0242ac110002 UniProtKB:O02604 biolink:molecularly_interacts_with DrugCentral:2282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proguanil targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) DrugCentral uuid:5e140512-6b31-11ec-b3df-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:2282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proguanil is inhibitor of Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) DrugCentral uuid:5e142998-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:2282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proguanil targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5e145256-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.909']} DrugCentral uuid:5e147bbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.704']} DrugCentral uuid:5e14a4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5e14cd9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.943']} DrugCentral uuid:5e14f6a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.337']} DrugCentral uuid:5e151ff6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:5e1548d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.529']} DrugCentral uuid:5e157258-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.796']} DrugCentral uuid:5e159c2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.656']} DrugCentral uuid:5e15c776-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:5e15f05c-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:5e161938-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.226']} DrugCentral uuid:5e164214-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5e166b68-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.799']} DrugCentral uuid:5e169444-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5e16bd2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.551']} DrugCentral uuid:5e16e674-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.825']} DrugCentral uuid:5e170f5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.412']} DrugCentral uuid:5e173840-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.056']} DrugCentral uuid:5e176130-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:5e178be2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.337']} DrugCentral uuid:5e17b7c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.796']} DrugCentral uuid:5e17e092-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:5e180950-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:5e18329a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.427']} DrugCentral uuid:5e185b80-6b31-11ec-b3df-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5e188448-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:5e18ad24-6b31-11ec-b3df-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:5e18d678-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.344']} DrugCentral uuid:5e18ff5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.806']} DrugCentral uuid:5e192862-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:5e19510c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5e197b50-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5e19a508-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:5e19d19a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5e19d19a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5e1a1826-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:5e1a1826-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:5e1a1826-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:5e1a1826-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:5e1a1826-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:5e1a787a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5e1a787a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5e1a787a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5e1ab9d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5e1ae2a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promegestone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5e1b0b8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promegestone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5e1b365c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:5e1b6168-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.609']} DrugCentral uuid:5e1b8a6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.592']} DrugCentral uuid:5e1bb3e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:5e1bdd32-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5e1c060e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.376']} DrugCentral uuid:5e1c2ef4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:5e1c57d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5e1c8106-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.367']} DrugCentral uuid:5e1ca9f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.188']} DrugCentral uuid:5e1cd2dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.948']} DrugCentral uuid:5e1cfd8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5e1d2322-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:5e1d4c08-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.721']} DrugCentral uuid:5e1d7502-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.62']} DrugCentral uuid:5e1d9e60-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.941']} DrugCentral uuid:5e1dc732-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.823']} DrugCentral uuid:5e1df022-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.479']} DrugCentral uuid:5e1e1912-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:5e1e4248-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.382']} DrugCentral uuid:5e1e6b38-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.975']} DrugCentral uuid:5e1e941e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:5e1ebcfa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.292']} DrugCentral uuid:5e1ee84c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.452']} DrugCentral uuid:5e1f1484-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5e1f3dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:5e1f66a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5e1f8ff4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5e1fb8b2-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:5e1fe170-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.678']} DrugCentral uuid:5e200be6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5e203490-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5e205d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:5e208e0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5e208e0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5e208e0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5e20d4d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:5e20fdbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5e212684-6b31-11ec-b3df-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5e214fb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP23 biolink:molecularly_interacts_with DrugCentral:2286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 promethazine targets Cytosolic other (Calmodulin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5e217922-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pronetalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5e21a21c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:5e21cb16-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:5e21f488-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5e221d5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:5e2241cc-6b31-11ec-b3df-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:5e226684-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:5e228c68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:5e22b0ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5e22d9d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:5e2302b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'ED50', 'has_quantitative_value': ['7.056']} DrugCentral uuid:5e232bf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.524']} DrugCentral uuid:5e2354d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.029']} DrugCentral uuid:5e237dbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.728']} DrugCentral uuid:5e23a6a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:5e23d000-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:5e23f904-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.063']} DrugCentral uuid:5e2421e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.602']} DrugCentral uuid:5e244ab2-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.498']} DrugCentral uuid:5e2474ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.829']} DrugCentral uuid:5e249dc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.337']} DrugCentral uuid:5e24c6a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:5e24f0f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.483']} DrugCentral uuid:5e2519e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5e2542b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e256b9a-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5e2594d0-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:5e25bd98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.845']} DrugCentral uuid:5e25e674-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.849']} DrugCentral uuid:5e260f46-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5e263a70-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5e26639c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.602']} DrugCentral uuid:5e269056-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5e269056-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propafenone targets Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5e26c6e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5e26efe2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:5e2718c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:5e2741c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propantheline is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.2']} DrugCentral uuid:5e276b98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5e27949c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:5e27bd82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:5e27e9e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5e27e9e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5e27e9e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proparacaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5e282fd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propentofylline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5e285abc-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (D(1A) dopamine receptor) DrugCentral uuid:5e287f2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (D(2) dopamine receptor) DrugCentral uuid:5e28a4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:5e28c95c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (5-hydroxytryptamine receptor 2C) DrugCentral uuid:5e28edf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5e29127c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5e293766-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:5e295be2-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:5e29805e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M4) DrugCentral uuid:5e29a4d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Muscarinic acetylcholine receptor M5) DrugCentral uuid:5e29c938-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (D(4) dopamine receptor) DrugCentral uuid:5e29ef4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiomazine targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:5e2a13de-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propiram is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:5e2a3864-6b31-11ec-b3df-0242ac110002 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.284']} DrugCentral uuid:5e2a6118-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.417']} DrugCentral uuid:5e2a8a4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.031']} DrugCentral uuid:5e2ab32a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:5e2adc42-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.218']} DrugCentral uuid:5e2b050a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.005']} DrugCentral uuid:5e2b2e36-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:5e2b56f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:5e2b7fbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.119']} DrugCentral uuid:5e2ba9b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5e2bd28c-6b31-11ec-b3df-0242ac110002 UniProtKB:O88704 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5e2c031a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5e2c031a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5e2c031a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5e2c4c1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5e2c4c1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5e2c4c1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2cc7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e2dadbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:5e2dadbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:5e2dadbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propofol is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:5e2dee82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.919']} DrugCentral uuid:5e2e17cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:5e2e4152-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:5e2e6a24-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.913']} DrugCentral uuid:5e2e9404-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.378']} DrugCentral uuid:5e2ebd3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.662']} DrugCentral uuid:5e2ee62a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5e2f0ef2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.847']} DrugCentral uuid:5e2f37ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.699']} DrugCentral uuid:5e2f62bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5e2f8bc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.197']} DrugCentral uuid:5e2fb488-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.346']} DrugCentral uuid:5e2fdd78-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5e3006e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.319']} DrugCentral uuid:5e302fd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:5e305898-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5e308142-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.297']} DrugCentral uuid:5e30aa82-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5e30d354-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.671']} DrugCentral uuid:5e30fc3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5e3125d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:5e314ec4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.01']} DrugCentral uuid:5e317796-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5e31a07c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5e31cb7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5e31f478-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.76']} DrugCentral uuid:5e3224e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:5e3224e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:5e3224e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:5e32670a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5e328ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:5e32b8d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:5e32e1c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.71']} DrugCentral uuid:5e330d40-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propranolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:5e3336b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07202 biolink:molecularly_interacts_with DrugCentral:2308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propylthiouracil is inhibitor of Enzyme (Thyroid peroxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5e335f70-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propylthiouracil targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5e338860-6b31-11ec-b3df-0242ac110002 UniProtKB:P49895 biolink:molecularly_interacts_with DrugCentral:2308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propylthiouracil is inhibitor of Enzyme (Type I iodothyronine deiodinase) DrugCentral uuid:5e33ad72-6b31-11ec-b3df-0242ac110002 UniProtKB:P59533 biolink:molecularly_interacts_with DrugCentral:2308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propylthiouracil targets GPCR (Taste receptor type 2 member 38) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5e33d662-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:2309 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propyphenazone is blocker of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.481']} DrugCentral uuid:5e33ff2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proquazone targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:5e3423b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proquazone targets Enzyme (Prostaglandin G/H synthase 1) DrugCentral uuid:5e344cfa-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proquazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5e344cfa-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proquazone targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5e3481ca-6b31-11ec-b3df-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:2313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proscillaridin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.056']} DrugCentral uuid:5e34aa7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proscillaridin targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:5e34d06c-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protionamide targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5e34fc90-6b31-11ec-b3df-0242ac110002 UniProtKB:P34981 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin is agonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5e352576-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01717 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin targets GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5e354e7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R297 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin targets GPCR (Protein Trhr2; Thyrotropin releasing hormone receptor 2; Thyrotropin-releasing hormone receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5e3577ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P21761 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin targets GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5e35a0aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERT1 biolink:molecularly_interacts_with DrugCentral:2316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protirelin targets GPCR (Thyrotropin-releasing hormone receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5e35c990-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protokylol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:5e35ee0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.928']} DrugCentral uuid:5e36174c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:5e364050-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.39']} DrugCentral uuid:5e366a1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5e369320-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5e36bf62-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5e36e848-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5e37111a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5e3739f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5e376336-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5e378c12-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:5e37b4f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:5e37de24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:5e38070a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protriptyline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:5e383112-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pseudoephedrine targets GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:5e38557a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pseudoephedrine targets GPCR (Alpha-2A adrenergic receptor) DrugCentral uuid:5e387b9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pseudoephedrine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:5e38a0ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pseudoephedrine targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:5e38c53c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5e38edf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5e39173a-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPB6 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Cyclopropane mycolic acid synthase 1) DrugCentral uuid:5e393bc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50575 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Amidase; Nicotinamidase; Nicotinamidase/pyrazinamidase; Pyrazinamidase; Pyrazinamidase/nicotinamidase; Pyrazinamidase/nicotinamidase PncA) DrugCentral uuid:5e396032-6b31-11ec-b3df-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5e398918-6b31-11ec-b3df-0242ac110002 UniProtKB:P95029 biolink:molecularly_interacts_with DrugCentral:2328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrazinamide is inhibitor of Enzyme (3-oxoacyl-ACP synthase; Fatty acid synthase Fas; Probable fatty acid synthase Fas (Fatty acid synthetase)) DrugCentral uuid:5e39ae2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridostigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5e39d724-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridostigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5e3a001e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:2330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5e3a28e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridostigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:5e3a5370-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.952']} DrugCentral uuid:5e3a7e18-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.184']} DrugCentral uuid:5e3aa78a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5e3ad066-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:5e3af99c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5e3b2296-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.751']} DrugCentral uuid:5e3b4b86-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.228']} DrugCentral uuid:5e3b74da-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5e3b9e24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.156']} DrugCentral uuid:5e3bc714-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:5e3befe6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5e3c18cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.5']} DrugCentral uuid:5e3c45d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepyramine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:5e3c6f8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.721']} DrugCentral uuid:5e3c9860-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5e3cc1aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.288']} DrugCentral uuid:5e3cea7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.409']} DrugCentral uuid:5e3d1362-6b31-11ec-b3df-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:5e3d3c48-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:5e3d659c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine is inhibitor of Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:5e3d8e8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5e3db74a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07382 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.602']} DrugCentral uuid:5e3de030-6b31-11ec-b3df-0242ac110002 UniProtKB:P22906 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5e3e0be6-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:5e3e3814-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:5e3e6424-6b31-11ec-b3df-0242ac110002 UniProtKB:Q27793 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.009']} DrugCentral uuid:5e3e8e54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine is inhibitor of Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5e3eb794-6b31-11ec-b3df-0242ac110002 UniProtKB:Q27783 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:5e3ee08e-6b31-11ec-b3df-0242ac110002 UniProtKB:O08966 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5e3f0aaa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K0H1 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Unclassified (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.84']} DrugCentral uuid:5e3f33ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5e3f5cbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P06865 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Beta-hexosaminidase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5e3f8584-6b31-11ec-b3df-0242ac110002 UniProtKB:P07686 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Beta-hexosaminidase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5e3fae56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3V050 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine is inhibitor of Unclassified (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5e3fd87c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:5e400176-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8I1R6 biolink:molecularly_interacts_with DrugCentral:2332 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrimethamine targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:5e402a66-6b31-11ec-b3df-0242ac110002 UniProtKB:F1KRD8 biolink:molecularly_interacts_with DrugCentral:2335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrvinium targets Unclassified (Fumarate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5e4053ec-6b31-11ec-b3df-0242ac110002 UniProtKB:O15056 biolink:molecularly_interacts_with DrugCentral:2335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrvinium targets Enzyme (Synaptojanin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5e407d22-6b31-11ec-b3df-0242ac110002 UniProtKB:O43426 biolink:molecularly_interacts_with DrugCentral:2335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrvinium targets Enzyme (Synaptojanin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5e40a608-6b31-11ec-b3df-0242ac110002 UniProtKB:P34897 biolink:molecularly_interacts_with DrugCentral:2335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrvinium targets Enzyme (Serine hydroxymethyltransferase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5e40d6a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.708']} DrugCentral uuid:5e40d6a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.708']} DrugCentral uuid:5e40d6a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.708']} DrugCentral uuid:5e412010-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.627']} DrugCentral uuid:5e412010-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.627']} DrugCentral uuid:5e412010-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.627']} DrugCentral uuid:5e4168b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:5e4168b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:5e4168b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quazepam is positive allosteric modulator of Ion channel (GABA A receptor alpha-2/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.688']} DrugCentral uuid:5e41ab84-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5e41d5c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5e41feae-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5e422794-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.483']} DrugCentral uuid:5e4250ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5e4279b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.016']} DrugCentral uuid:5e42a296-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5e42cb72-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5e42f4a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:5e431da2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.131']} DrugCentral uuid:5e43464c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:5e436f28-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5e439908-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5e43c1ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.512']} DrugCentral uuid:5e43ead4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.027']} DrugCentral uuid:5e441400-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.127']} DrugCentral uuid:5e443cfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5e4465c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5e448ed0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.35']} DrugCentral uuid:5e44b7e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:5e44e0a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.037']} DrugCentral uuid:5e450982-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.795']} DrugCentral uuid:5e453394-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.266']} DrugCentral uuid:5e455f18-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.524']} DrugCentral uuid:5e4587fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:5e45b0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.822']} DrugCentral uuid:5e45da9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5e4603fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.241']} DrugCentral uuid:5e462cd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e4655d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.457']} DrugCentral uuid:5e467efc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:5e46a7d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.506']} DrugCentral uuid:5e46d0aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5e46f9a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5e472438-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.866']} DrugCentral uuid:5e474d32-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.936']} DrugCentral uuid:5e47760e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.06']} DrugCentral uuid:5e479fa8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5e47c910-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5e47f1f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5e481b18-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5e4843f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5e486d20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e489606-6b31-11ec-b3df-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:2337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quetiapine targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5e48beec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.068']} DrugCentral uuid:5e48e7d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.542']} DrugCentral uuid:5e4913a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.119']} DrugCentral uuid:5e493c96-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.079']} DrugCentral uuid:5e496586-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:5e498eda-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.459']} DrugCentral uuid:5e49b7d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.445']} DrugCentral uuid:5e49e1aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.465']} DrugCentral uuid:5e4a0a9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.575']} DrugCentral uuid:5e4a33da-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.558']} DrugCentral uuid:5e4a5cde-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.571']} DrugCentral uuid:5e4a85b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.481']} DrugCentral uuid:5e4aae8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:5e4ad9b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.994']} DrugCentral uuid:5e4b03d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.574']} DrugCentral uuid:5e4b2c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04156 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Surface antigen (Major prion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5e4b5562-6b31-11ec-b3df-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.72']} DrugCentral uuid:5e4b7ec0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:5e4ba7b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5e4bd096-6b31-11ec-b3df-0242ac110002 UniProtKB:P02752 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Unclassified (Riboflavin-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.58']} DrugCentral uuid:5e4bfdaa-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5e4bfdaa-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5e4c3b80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5e4c3b80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5e4c3b80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5e4c87ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5e4c87ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5e4c87ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5e4c87ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Bacterial DNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5e4cd7fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P00592 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Phospholipase A2 group 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5e4d00d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04055 biolink:molecularly_interacts_with DrugCentral:2338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepacrine targets Enzyme (Phospholipase A2 group 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4d5b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e4e285a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:5e4e285a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:5e4e285a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:5e4e6ce8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5e4e6ce8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5e4eaa46-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5e4eaa46-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5e4eaa46-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinagolide targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5e4eeb0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2340 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.08']} DrugCentral uuid:5e4f144a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2340 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.397']} DrugCentral uuid:5e4f3d08-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinestrol is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:5e4f61a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:2343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinethazone is inhibitor of Transporter (Solute carrier family 12 member 3) DrugCentral uuid:5e4f8628-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quingestanol acetate is agonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:5e4fac52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5e4fd51a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07699 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-1) DrugCentral uuid:5e4ff996-6b31-11ec-b3df-0242ac110002 UniProtKB:O60939 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-2) DrugCentral uuid:5e501e08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY72 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-3) DrugCentral uuid:5e50440a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IWT1 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Sodium channel subunit beta-4) DrugCentral uuid:5e506a20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5e5092fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5e50bbc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.125']} DrugCentral uuid:5e50e50e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:5e510dcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5e5136b2-6b31-11ec-b3df-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e515f8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.106']} DrugCentral uuid:5e5188a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5e51b182-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5e51da40-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.061']} DrugCentral uuid:5e520312-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:5e5236c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5e5236c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5e5236c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5e52787e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5e52a16e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63881 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine targets Ion channel (Potassium voltage-gated channel subfamily D member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5e52cae0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z258 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5e52f3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P15389 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5e531ca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinidine is inhibitor of Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.921']} DrugCentral uuid:5e534592-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.101']} DrugCentral uuid:5e536fe0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.102']} DrugCentral uuid:5e5398a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.119']} DrugCentral uuid:5e53c170-6b31-11ec-b3df-0242ac110002 UniProtKB:P05023 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Transporter (Sodium/potassium-transporting ATPase subunit alpha-1) DrugCentral uuid:5e53e614-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5e540fd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:5e543c90-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:5e543c90-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:5e546c38-6b31-11ec-b3df-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5e54958c-6b31-11ec-b3df-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5e54be72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5e54e744-6b31-11ec-b3df-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5e551034-6b31-11ec-b3df-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5e553974-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:2350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rabeprazole targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:5e556250-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.321']} DrugCentral uuid:5e558b0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.714']} DrugCentral uuid:5e55b3fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.408']} DrugCentral uuid:5e55dda2-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.926']} DrugCentral uuid:5e560688-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.205']} DrugCentral uuid:5e562f5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5e56582c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5e5681c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.721']} DrugCentral uuid:5e56aaa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.553']} DrugCentral uuid:5e56d374-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.383']} DrugCentral uuid:5e56fdf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:5e5726e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5e574fe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5e5779aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.773']} DrugCentral uuid:5e57a380-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:5e57cc66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.538']} DrugCentral uuid:5e57f52e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.523']} DrugCentral uuid:5e581e0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.971']} DrugCentral uuid:5e5847a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.828']} DrugCentral uuid:5e58708a-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:5e589952-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.321']} DrugCentral uuid:5e58c238-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.193']} DrugCentral uuid:5e58eb8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene is antagonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5e59144a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:5e593d30-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.398']} DrugCentral uuid:5e5965f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5e599262-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene is modulator of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5e59be04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5e59e79e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Cytokine (Interleukin-6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5e5a117e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.436']} DrugCentral uuid:5e5a3a32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:5e5a62fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.876']} DrugCentral uuid:5e5a8bcc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13393 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Phospholipase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e5ab520-6b31-11ec-b3df-0242ac110002 UniProtKB:O14939 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Phospholipase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5e5adde8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.827']} DrugCentral uuid:5e5b06d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.073']} DrugCentral uuid:5e5b2fbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.625']} DrugCentral uuid:5e5b5b06-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5e5b84be-6b31-11ec-b3df-0242ac110002 UniProtKB:P06211 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:5e5bad9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transcription factor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:5e5bd680-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:5e5c002e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:5e5c2cca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.73']} DrugCentral uuid:5e5c2cca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.73']} DrugCentral uuid:5e5c617c-6b31-11ec-b3df-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5e5c8ac6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5e5cb398-6b31-11ec-b3df-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raloxifene targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5e5cdc88-6b31-11ec-b3df-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:2352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltegravir is inhibitor of Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.523']} DrugCentral uuid:5e5d0564-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:2352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5e5d3124-6b31-11ec-b3df-0242ac110002 UniProtKB:P32246 biolink:molecularly_interacts_with DrugCentral:2352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltegravir targets GPCR (C-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5e5d5a00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:2352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5e5d82d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5e5dacda-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.678']} DrugCentral uuid:5e5dd674-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.32']} DrugCentral uuid:5e5dff32-6b31-11ec-b3df-0242ac110002 UniProtKB:P14207 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Membrane receptor (Folate receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5e5e2804-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5e5e5144-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A884 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.244']} DrugCentral uuid:5e5e7a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07607 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5e5ea310-6b31-11ec-b3df-0242ac110002 UniProtKB:P45352 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5e5ecbe2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00469 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5e5ef630-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5e5f2146-6b31-11ec-b3df-0242ac110002 UniProtKB:C3SWJ7 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Enzyme (Thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5e5f4a0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5e5f73bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:2353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raltitrexed targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5e5f9dba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.37']} DrugCentral uuid:5e5fc696-6b31-11ec-b3df-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban is inverse agonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:5e5fef72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5e60183a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XKD3 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban is antagonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5e6041e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z2J6 biolink:molecularly_interacts_with DrugCentral:2354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramatroban is antagonist of GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5e606ace-6b31-11ec-b3df-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:2355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramelteon is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.9']} DrugCentral uuid:5e6093dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:2355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramelteon is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.39']} DrugCentral uuid:5e60bd44-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramipril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.342']} DrugCentral uuid:5e60e846-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramipril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5e611122-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2357 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramosetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:5e6139fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.86']} DrugCentral uuid:5e61633e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5e618c06-6b31-11ec-b3df-0242ac110002 UniProtKB:P47747 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5e61b514-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5e61ddd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25102 biolink:molecularly_interacts_with DrugCentral:2358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranitidine is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5e620794-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranolazine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5e623048-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranolazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:5e625910-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranolazine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5e627da0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5YLN7 biolink:molecularly_interacts_with DrugCentral:2359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranolazine targets Unclassified (Voltage-gated sodium channel Nav1.5 cardiac isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5e62a8b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:2360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rebamipide is agonist of GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e62d1ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5e62fad2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:5e6323a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:5e634ce4-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:5e63769c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5e639f78-6b31-11ec-b3df-0242ac110002 UniProtKB:P48051 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.194']} DrugCentral uuid:5e63c85e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5e63f1e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.86']} DrugCentral uuid:5e641ac0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.16']} DrugCentral uuid:5e644766-6b31-11ec-b3df-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.317']} DrugCentral uuid:5e644766-6b31-11ec-b3df-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.317']} DrugCentral uuid:5e6483f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.387']} DrugCentral uuid:5e6483f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48549 biolink:molecularly_interacts_with DrugCentral:2361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reboxetine targets Ion channel (Kir3.1/Kir3.4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.387']} DrugCentral uuid:5e64bab6-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson is agonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.886']} DrugCentral uuid:5e64e36a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.398']} DrugCentral uuid:5e650c82-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5e653540-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5e655e26-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regadenoson targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:5e658720-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remifentanil is agonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:5e65ac5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remifentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5e65d522-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remifentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5e65fe08-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5e662770-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:5e665100-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e6679c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.509']} DrugCentral uuid:5e66a2a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:5e66cb8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5e66f4de-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5e671da6-6b31-11ec-b3df-0242ac110002 UniProtKB:P52702 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5e6746a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P52703 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5e678070-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e678070-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e678070-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e678070-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e678070-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remoxipride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e67d908-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09428 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide targets Ion channel (ATP-binding cassette sub-family C member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5e6801c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide targets Transporter (Solute carrier organic anion transporter family member 1B1) DrugCentral uuid:5e6827f0-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5e6854b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:5e6854b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:5e688d80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:5e688d80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 repaglinide is blocker of Ion channel (Sulfonylurea receptor 2, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:5e68c2dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2368 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reproterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:5e68e76c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:2369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rescinnamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:5e690c1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.773']} DrugCentral uuid:5e6934d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.415']} DrugCentral uuid:5e695e40-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.232']} DrugCentral uuid:5e698708-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5e69afc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.737']} DrugCentral uuid:5e69d8a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.223']} DrugCentral uuid:5e6a039a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:5e6a2c6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5e6a5534-6b31-11ec-b3df-0242ac110002 UniProtKB:Q27963 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5e6a7f50-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A0J7 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Quinolone resistance protein NorA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5e6aa87c-6b31-11ec-b3df-0242ac110002 UniProtKB:P54219 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine is inhibitor of Transporter (Chromaffin granule amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:5e6ad914-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e6ad914-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e6ad914-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e6b1b36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BRU6 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:5e6b44bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2370 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reserpine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.836']} DrugCentral uuid:5e6b6d98-6b31-11ec-b3df-0242ac110002 UniProtKB:P02753 biolink:molecularly_interacts_with DrugCentral:2372 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol acetate targets Secreted (Retinol-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5e6b9674-6b31-11ec-b3df-0242ac110002 UniProtKB:P02754 biolink:molecularly_interacts_with DrugCentral:2372 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol acetate targets Unclassified (Beta-lactoglobulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:5e6bc086-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5e6be9e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P55263 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets Kinase (Adenosine kinase) DrugCentral uuid:5e6c0e74-6b31-11ec-b3df-0242ac110002 UniProtKB:P22413 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets Enzyme (Ectonucleotide pyrophosphatase/phosphodiesterase family member 1) DrugCentral uuid:5e6c32dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P49902 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets Enzyme (Cytosolic purine 5'-nucleotidase) DrugCentral uuid:5e6c57e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5e6c8174-6b31-11ec-b3df-0242ac110002 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5e6caa46-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:5e6cd304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin is inhibitor of Enzyme (NS5B protein) DrugCentral uuid:5e6cf834-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribavirin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5e6d2110-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WGY9 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin targets Enzyme (DNA-directed RNA polymerase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5e6d557c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:5e6d557c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:5e6d557c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:5e6d557c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifabutin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:5e6d9a3c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e6dc2f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5e6debae-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.95']} DrugCentral uuid:5e6e1480-6b31-11ec-b3df-0242ac110002 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5e6e3dac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5e6e6688-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:5e6e8f64-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin is inhibitor of Enzyme (DNA-directed RNA polymerase subunit beta) DrugCentral uuid:5e6eb4e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:5e6edeec-6b31-11ec-b3df-0242ac110002 UniProtKB:P46721 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.29']} DrugCentral uuid:5e6f07e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPD5 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e6f30ae-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5e6f5976-6b31-11ec-b3df-0242ac110002 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:2377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifampicin targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:5e6f8eaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:5e6f8eaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:5e6f8eaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:5e6f8eaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifapentine is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:5e6fd23e-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5e7006dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:5e7006dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:5e7006dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:5e7006dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:2379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifaximin is inhibitor of Enzyme (Bacterial DNA-directed RNA polymerase) DrugCentral uuid:5e704c0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:5e7074f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5e709e94-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:5e70c77a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5e70f060-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:5e711950-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:2381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilmenidine targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.95']} DrugCentral uuid:5e7143bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5e7168c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5e7191a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.765']} DrugCentral uuid:5e71ba90-6b31-11ec-b3df-0242ac110002 UniProtKB:O15554 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Intermediate conductance calcium-activated potassium channel protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5e71e3b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCU5 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole targets Ion channel (Glutamate receptor ionotropic, NMDA 3A) DrugCentral uuid:5e720842-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UGI6 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5e7230f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e725afe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92952 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Small conductance calcium-activated potassium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5e7284fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5e72adba-6b31-11ec-b3df-0242ac110002 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:2382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riluzole is activator of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5e72d682-6b31-11ec-b3df-0242ac110002 UniProtKB:P21430 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Ion channel (Matrix protein 2) DrugCentral uuid:5e72fb08-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:5e73266e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5e735288-6b31-11ec-b3df-0242ac110002 UniProtKB:P63231 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine is inhibitor of Ion channel (Matrix protein 2) DrugCentral uuid:5e73774a-6b31-11ec-b3df-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5e73a03a-6b31-11ec-b3df-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Unclassified (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5e73c9b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P05778 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5e73f29c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DOF8 biolink:molecularly_interacts_with DrugCentral:2383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimantadine targets Unclassified (Matrix protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5e741b78-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimexolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e7478d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripazepam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5e75590c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:2387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risedronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:5e7582a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:2387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risedronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5e75abaa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q197X6 biolink:molecularly_interacts_with DrugCentral:2387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risedronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.13']} DrugCentral uuid:5e75d472-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WS26 biolink:molecularly_interacts_with DrugCentral:2387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risedronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:5e75fd4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5e7626c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:5e764fba-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5e76786e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04274 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:5e76a168-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5e76cc6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levisoprenaline targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5e76f550-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5e771e0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5e7746fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:5e77708e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:5e779974-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5e77c25a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5e77eb22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.788']} DrugCentral uuid:5e781480-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5e783df2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.443']} DrugCentral uuid:5e7866ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.364']} DrugCentral uuid:5e7890ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5e78ba2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5e78e40a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:5e790ce6-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:5e793676-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:5e795f5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5e79884c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:5e79b128-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.023']} DrugCentral uuid:5e79da54-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:5e7a0344-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:5e7a2c2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5e7a54fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.432']} DrugCentral uuid:5e7a8134-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5e7aaa42-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.538']} DrugCentral uuid:5e7ad328-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:5e7afc86-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5e7b254e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.495']} DrugCentral uuid:5e7b4e34-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.278']} DrugCentral uuid:5e7b772e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5e7ba06e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5e7bc92c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:5e7bf1fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5e7c1ab2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.687']} DrugCentral uuid:5e7c46c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5e7c700c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5e7c98f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.967']} DrugCentral uuid:5e7cc1ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5e7cec62-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5e7d1534-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5e7d3e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5e7d670a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:5e7d905e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5e7db93a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5e7de22a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5e7e0c00-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5e7e354a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61168 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5e7e5e1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.84']} DrugCentral uuid:5e7e870c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5e7eb074-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5e7ed964-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.01']} DrugCentral uuid:5e7f0268-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5e7f2b58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5e7f557e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5e7f7e5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e7fb29e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5e7fb29e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5e7fb29e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5e7fb29e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5e8008fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:5e8008fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:5e8008fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:5e80519a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5e80519a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5e80519a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02152 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5e809466-6b31-11ec-b3df-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:2389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risperidone targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5e80bd6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritodrine is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:5e80e61e-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritodrine targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5e810efa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.575']} DrugCentral uuid:5e813830-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5e816120-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:5e8189de-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.301']} DrugCentral uuid:5e81b346-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:5e81d948-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:5e82022e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:5e822b00-6b31-11ec-b3df-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.303']} DrugCentral uuid:5e8255c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:5e827ec0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.119']} DrugCentral uuid:5e82a79c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:5e82d096-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.058']} DrugCentral uuid:5e82f9fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir is inhibitor of Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5e8322ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:5e834bfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22309 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir is inhibitor of Enzyme (UDP-glucuronosyltransferase 1-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5e8374c4-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:5e839ff8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5e83ca32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:5e83f304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:2391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ritonavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.47']} DrugCentral uuid:5e841c12-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:5e8445ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine is inhibitor of Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5e846f8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:5e84985e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5e84c194-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5e84ea7a-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5e851338-6b31-11ec-b3df-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5e853c14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5e856644-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5e858f98-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivastigmine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:5e85b8ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5e85e1be-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5e860b4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5e86343e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5e865d2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5e868600-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.854']} DrugCentral uuid:5e86af40-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5e86d808-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5e8700ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5e8729c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P79400 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5e875a26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e875a26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rizatriptan targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5e8797ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5e8797ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5e8797ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5e87e482-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5e87e482-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5e87e482-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5e87e482-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rocuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5e88327a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.51']} DrugCentral uuid:5e885b4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5e88846e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.466']} DrugCentral uuid:5e88ae76-6b31-11ec-b3df-0242ac110002 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5e88d748-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5e890006-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:5e8929a0-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5e895268-6b31-11ec-b3df-0242ac110002 UniProtKB:P35355 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5e897b26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:5e89a4b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:2397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rofecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5e89cda6-6b31-11ec-b3df-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolitetracycline targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5e89f664-6b31-11ec-b3df-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:2399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolitetracycline targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5e8a1f68-6b31-11ec-b3df-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:2399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolitetracycline targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5e8a4894-6b31-11ec-b3df-0242ac110002 UniProtKB:P43351 biolink:molecularly_interacts_with DrugCentral:2399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolitetracycline targets Nuclear other (DNA repair protein RAD52 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5e8a715c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5e8a9a42-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:5e8ac314-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:5e8aed3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:5e8b1616-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5e8b3ed4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5e8b67a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5e8b9104-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5e8bb9fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:5e8be3de-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:5e8c0ca6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.86']} DrugCentral uuid:5e8c36a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5e8c5f8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5e8c8866-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5e8cb25a-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5e8cde9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropinirole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:5e8d07fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:5e8d30cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:5e8d55fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) DrugCentral uuid:5e8d7afa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 3 subunit alpha) DrugCentral uuid:5e8d9f6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35499 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 4 subunit alpha) DrugCentral uuid:5e8dc3fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 8 subunit alpha) DrugCentral uuid:5e8de92c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) DrugCentral uuid:5e8e0dbc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:5e8e3238-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5e8e5b0a-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropivacaine targets Ion channel (Potassium channel subfamily K member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5e8e847c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5e8eaf10-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.391']} DrugCentral uuid:5e8ed7e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5e8f00b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5e8f29ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.56']} DrugCentral uuid:5e8f5410-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:5e8f7cec-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:5e8fa5d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5e8fcf76-6b31-11ec-b3df-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5e8ff960-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.449']} DrugCentral uuid:5e902228-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5e904afa-6b31-11ec-b3df-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5e9075ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5e909ea6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5e90c7a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transcription factor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5e90f05e-6b31-11ec-b3df-0242ac110002 UniProtKB:P37238 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transcription factor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5e9119a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:5e91427a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone is activator of Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:5e916b56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5e91948c-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5e91be08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5e91e6f8-6b31-11ec-b3df-0242ac110002 UniProtKB:B0K020 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5e920fde-6b31-11ec-b3df-0242ac110002 UniProtKB:P23204 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5e92395a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5e926254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5e928b08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N5K1 biolink:molecularly_interacts_with DrugCentral:2405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosiglitazone targets Unclassified (CDGSH iron-sulfur domain-containing protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5e92b3ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosuvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:5e92dd56-6b31-11ec-b3df-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosuvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:5e930632-6b31-11ec-b3df-0242ac110002 UniProtKB:O43924 biolink:molecularly_interacts_with DrugCentral:2406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rosuvastatin targets Enzyme (Phosphodiesterase 6D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5e932f0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5e9357ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:5e938148-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5e93aa2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5e93d40e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:5e93fce0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95136 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5e9426a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P20288 biolink:molecularly_interacts_with DrugCentral:2407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rotigotine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5e944fb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxatidine acetate is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5e947878-6b31-11ec-b3df-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:2410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxithromycin targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:5e949d08-6b31-11ec-b3df-0242ac110002 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:2410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxithromycin is agonist of GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5e94c67a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxithromycin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.261']} DrugCentral uuid:5e94ef74-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rupatadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.41']} DrugCentral uuid:5e951832-6b31-11ec-b3df-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:2413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rupatadine targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5e954186-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5e956a62-6b31-11ec-b3df-0242ac110002 UniProtKB:P17708 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Enzyme (S-adenosylmethionine decarboxylase proenzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5e959348-6b31-11ec-b3df-0242ac110002 UniProtKB:C3SIU2 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Unclassified (Met repressor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5e95bc06-6b31-11ec-b3df-0242ac110002 UniProtKB:P11086 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Enzyme (Phenylethanolamine N-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5e95e596-6b31-11ec-b3df-0242ac110002 UniProtKB:P22061 biolink:molecularly_interacts_with DrugCentral:2414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ademetionine targets Enzyme (Protein-beta-aspartate methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:5e960e7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5e9638a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5e96616a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.95']} DrugCentral uuid:5e968b04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6RYA0 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Salicylic acid-binding protein 2) DrugCentral uuid:5e96af8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5e96d8a2-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5e970174-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:5e972ad2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5e9753a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5e977c94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:5e97a61a-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5e97cfdc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5e97f9da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.36']} DrugCentral uuid:5e9822c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5e984c46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salicylic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:5e98754a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5e989e30-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.41']} DrugCentral uuid:5e98c716-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5e98f056-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:5e991928-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.004']} DrugCentral uuid:5e9941f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5e996ac2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5e999574-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5e99beb4-6b31-11ec-b3df-0242ac110002 UniProtKB:P34971 biolink:molecularly_interacts_with DrugCentral:2419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 salmeterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5e99e79a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.408']} DrugCentral uuid:5e9a10c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:5e9a3a42-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.921']} DrugCentral uuid:5e9a630a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.612']} DrugCentral uuid:5e9a8bf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.282']} DrugCentral uuid:5e9ab4d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Canalicular multispecific organic anion transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.699']} DrugCentral uuid:5e9ade34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.555']} DrugCentral uuid:5e9b072e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.556']} DrugCentral uuid:5e9b3000-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:5e9b551c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.003']} DrugCentral uuid:5e9b7fd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.153']} DrugCentral uuid:5e9ba8b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.187']} DrugCentral uuid:5e9bd19a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.661']} DrugCentral uuid:5e9bfad0-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.684']} DrugCentral uuid:5e9c24b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:5e9c4d8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5e9c765e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5e9ca052-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:5e9cc94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5e9cf368-6b31-11ec-b3df-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:5e9d1c58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:2422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saquinavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:5e9d45f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5e9d6ece-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5e9d97c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5e9dc946-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:5e9dc946-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:5e9dc946-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarpogrelate targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:5e9e0a32-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5e9e3304-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.86']} DrugCentral uuid:5e9e5bea-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5e9e8584-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:5e9eae88-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.75']} DrugCentral uuid:5e9ed782-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5e9f0162-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.28']} DrugCentral uuid:5e9f2a52-6b31-11ec-b3df-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:5e9f5324-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WMX0 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:5e9f7c1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:5e9fb490-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:5e9fb490-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:5e9fb490-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:5e9fb490-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:5e9fb490-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 scopolamine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:5ea00e90-6b31-11ec-b3df-0242ac110002 UniProtKB:C3TDZ2 biolink:molecularly_interacts_with DrugCentral:2427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secnidazole targets Enzyme (3-oxoacyl-[acyl-carrier-protein] synthase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5ea037f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:2428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secobarbital targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.578']} DrugCentral uuid:5ea06890-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5ea06890-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5ea06890-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secobarbital is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5ea0a1de-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.171']} DrugCentral uuid:5ea0cac4-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.764']} DrugCentral uuid:5ea0f51c-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:5ea11e0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5ea146f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:5ea1703c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5ea19936-6b31-11ec-b3df-0242ac110002 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5ea1c212-6b31-11ec-b3df-0242ac110002 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5ea1eed6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5ea1eed6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selegiline targets Enzyme (Monoamine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5ea2245a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:2432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 seratrodast targets GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:5ea24d22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02643 biolink:molecularly_interacts_with DrugCentral:2433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sermorelin is agonist of GPCR (Growth hormone-releasing hormone receptor) DrugCentral uuid:5ea271d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertaconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:5ea29656-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:2434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertaconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5ea2bfbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5ea2e9da-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5ea312b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5ea33b92-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.194']} DrugCentral uuid:5ea365c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:5ea38ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5ea3b7fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5ea3e16e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5ea40a40-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.553']} DrugCentral uuid:5ea4333a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.745']} DrugCentral uuid:5ea45c0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.347']} DrugCentral uuid:5ea48650-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:5ea4af86-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.29']} DrugCentral uuid:5ea4d858-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5ea5013e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:5ea52a9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5ea55364-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.347']} DrugCentral uuid:5ea57c72-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5ea5a544-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5ea5cf10-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5ea5f7d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:5ea620b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:5ea6497c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:5ea67334-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5ea69c1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5ea6c51e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.29']} DrugCentral uuid:5ea6ee4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:5ea7173a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.48']} DrugCentral uuid:5ea747a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5ea747a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5ea747a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5ea7920a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.41']} DrugCentral uuid:5ea7920a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.41']} DrugCentral uuid:5ea7920a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.41']} DrugCentral uuid:5ea7d2ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:5ea7fbaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5ea824a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2435 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertindole is inverse agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5ea84f2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.965']} DrugCentral uuid:5ea87814-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:5ea8a10e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.167']} DrugCentral uuid:5ea8ca8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.54']} DrugCentral uuid:5ea8f35c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5ea91c42-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.106']} DrugCentral uuid:5ea94690-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.666']} DrugCentral uuid:5ea97020-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.246']} DrugCentral uuid:5ea99924-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.863']} DrugCentral uuid:5ea9c200-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.082']} DrugCentral uuid:5ea9eb86-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.128']} DrugCentral uuid:5eaa1656-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:5eaa3f3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.886']} DrugCentral uuid:5eaa6804-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.854']} DrugCentral uuid:5eaa90fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.721']} DrugCentral uuid:5eaaba5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.187']} DrugCentral uuid:5eaae32e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5eab0d04-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5eab3694-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.475']} DrugCentral uuid:5eab5f66-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.365']} DrugCentral uuid:5eab8856-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.885']} DrugCentral uuid:5eabb132-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:5eabdbb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:5eac0574-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5eac2e5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sertraline targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5eac5736-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5eac7c34-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive modulator of Ion channel (Glycine receptor subunit alpha-1) DrugCentral uuid:5eaca0c4-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 2) DrugCentral uuid:5eacc554-6b31-11ec-b3df-0242ac110002 UniProtKB:O14649 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 3) DrugCentral uuid:5eacea0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 9) DrugCentral uuid:5ead0f5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P57789 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 10) DrugCentral uuid:5ead33f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7Z418 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is opener of Ion channel (Potassium channel subfamily K member 18) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5ead9146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sevoflurane is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5eae5978-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.526']} DrugCentral uuid:5eae8394-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.263']} DrugCentral uuid:5eaeac7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.962']} DrugCentral uuid:5eaed560-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine targets GPCR (Alpha-2C adrenergic receptor) DrugCentral uuid:5eaefa9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.026']} DrugCentral uuid:5eaf2380-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK17 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine targets Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5eaf4c3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is inhibitor of Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5eaf74f2-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.538']} DrugCentral uuid:5eafa198-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62897 biolink:molecularly_interacts_with DrugCentral:2440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sibutramine is blocker of Ion channel (Potassium voltage-gated channel subfamily D member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5eafcaba-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5eaff382-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5eb01cb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5eb04620-6b31-11ec-b3df-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Transporter (Multidrug resistance-associated protein 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5eb06ef2-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5eb097a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P16499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) DrugCentral uuid:5eb0bc7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5eb0e526-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5eb10e0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5eb136d4-6b31-11ec-b3df-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5eb1619a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13946 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5eb18a6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51160 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:5eb1b316-6b31-11ec-b3df-0242ac110002 UniProtKB:O76083 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5eb1dbe8-6b31-11ec-b3df-0242ac110002 UniProtKB:O60658 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5eb2065e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.094']} DrugCentral uuid:5eb22f58-6b31-11ec-b3df-0242ac110002 UniProtKB:O54735 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.74']} DrugCentral uuid:5eb25820-6b31-11ec-b3df-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5eb281c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28156 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5eb2ab18-6b31-11ec-b3df-0242ac110002 UniProtKB:P16586 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5eb2d3f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P11541 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5eb2fcc6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5eb326a6-6b31-11ec-b3df-0242ac110002 UniProtKB:O77746 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5eb3534c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5eb3534c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5eb3937a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5eb3937a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5eb3937a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5eb3937a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5eb3ec62-6b31-11ec-b3df-0242ac110002 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5eb3ec62-6b31-11ec-b3df-0242ac110002 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5eb3ec62-6b31-11ec-b3df-0242ac110002 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5eb3ec62-6b31-11ec-b3df-0242ac110002 UniProtKB:P54748 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5eb440a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5eb440a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5eb440a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5eb48708-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5eb48708-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5eb4ceb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5eb4ceb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5eb4ceb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5eb4ceb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5eb4ceb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5eb4ceb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5eb53c7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5eb53c7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5eb53c7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EPR9 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5eb57d20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPD5 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5eb5a6b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14099 biolink:molecularly_interacts_with DrugCentral:2441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sildenafil targets Enzyme (Phosphodiesterase 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:5eb5cf6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5eb5f836-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5eb620fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:5eb64a52-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5eb67342-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.99']} DrugCentral uuid:5eb69c28-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5eb6c4dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.73']} DrugCentral uuid:5eb6ef70-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5eb718e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5eb741c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5eb76b44-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5eb7942a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:5eb7bd06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.93']} DrugCentral uuid:5eb7e5e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:5eb80f04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5eb837d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5eb860bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22985 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5eb88a74-6b31-11ec-b3df-0242ac110002 UniProtKB:P21447 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Transporter (P-glycoprotein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5eb8b59e-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:5eb8dfc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14142 biolink:molecularly_interacts_with DrugCentral:2443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silymarin targets Transporter (Solute carrier family 2, facilitated glucose transporter member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5eb908aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:5eb92d3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin is inhibitor of Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5eb95698-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5eb97f92-6b31-11ec-b3df-0242ac110002 UniProtKB:P51639 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:5eb9a86e-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5eb9d14a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q10283 biolink:molecularly_interacts_with DrugCentral:2445 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simvastatin targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:5eb9fa80-6b31-11ec-b3df-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.431']} DrugCentral uuid:5eba235c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5eba4c1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5eba76e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:5ebaa0ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:5ebac99c-6b31-11ec-b3df-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:5ebaf246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00688 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5ebb1bc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:5ebb4502-6b31-11ec-b3df-0242ac110002 UniProtKB:P68106 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5ebb6dd4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13451 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5ebb96ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q53EL6 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Nuclear other (Programmed cell death protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5ebbbffa-6b31-11ec-b3df-0242ac110002 UniProtKB:P06730 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Nuclear other (Eukaryotic translation initiation factor 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5ebbe8cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P26883 biolink:molecularly_interacts_with DrugCentral:2446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:5ebc1194-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A7S3 biolink:molecularly_interacts_with DrugCentral:2447 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sisomicin targets Cytosolic other (30S ribosomal protein S12) DrugCentral uuid:5ebc361a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14740 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5ebc6068-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5ebc8ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.774']} DrugCentral uuid:5ebcb3a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28843 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:5ebcdc64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:5ebd05ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5ebd2eb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5ebd5784-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHL4 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Enzyme (Dipeptidyl peptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5ebd804c-6b31-11ec-b3df-0242ac110002 UniProtKB:O31048 biolink:molecularly_interacts_with DrugCentral:2448 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitagliptin targets Unclassified (Dipeptidyl peptidase IV) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:5ebda98c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES7 biolink:molecularly_interacts_with DrugCentral:2449 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitafloxacin targets Enzyme (DNA gyrase subunit B) DrugCentral uuid:5ebdcdf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P72525 biolink:molecularly_interacts_with DrugCentral:2449 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitafloxacin targets Enzyme (DNA topoisomerase 4 subunit A) DrugCentral uuid:5ebdf28e-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:5ebe1b60-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:5ebe4572-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5ebe6e4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5ebe9716-6b31-11ec-b3df-0242ac110002 UniProtKB:P19838 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Cytosolic other (Nuclear factor NF-kappa-B p105 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5ebec09c-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5ebee96e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5ebf1240-6b31-11ec-b3df-0242ac110002 UniProtKB:P06746 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (DNA polymerase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:5ebf3b08-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5ebf6420-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5ebf8cfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:5ebfb5d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitosterol targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:5ebfdedc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:2452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sivelestat targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5ec00952-6b31-11ec-b3df-0242ac110002 UniProtKB:P24158 biolink:molecularly_interacts_with DrugCentral:2452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sivelestat targets Enzyme (Myeloblastin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5ec031fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3UP87 biolink:molecularly_interacts_with DrugCentral:2452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sivelestat targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:5ec05ace-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5ec083be-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5ec0ae3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.88']} DrugCentral uuid:5ec0d6fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5ec0ffce-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5ec129e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5ec15320-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5ec17bfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solifenacin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5ec1a4ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5ec1cf9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:5ec1f8d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.71']} DrugCentral uuid:5ec221ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.25']} DrugCentral uuid:5ec24a8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5ec2741c-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5ec29cee-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5ec2c5ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5ec2eec4-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:5ec31818-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5ec3411c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5ec36a0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:5ec392e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5ec3bcdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5ec3e5a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5ec40e62-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:5ec43734-6b31-11ec-b3df-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5ec460e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:5ec489be-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5ec4b39e-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.35']} DrugCentral uuid:5ec4dd06-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:5ec50600-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5ec52efa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.68']} DrugCentral uuid:5ec557fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5ec581f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5ec5aad8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5ec5d3aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5ec5fc86-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5ec62616-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5ec64ef2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5ec677ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5ec6a0aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5ec6c9ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5ec6f2b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5ec71b8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:5ec7446a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5ec770de-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5ec79cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5ec7c82c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5ec7f194-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00535 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent-like kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5ec81b92-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5ec84478-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5ec86d36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5ec89662-6b31-11ec-b3df-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5ec8c038-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5ec8e91e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15759 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5ec911fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5ec93bee-6b31-11ec-b3df-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5ec964b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5ec98d74-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5ec9b646-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5ec9dfae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5eca086c-6b31-11ec-b3df-0242ac110002 UniProtKB:P53778 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5eca3170-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5eca5aba-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5eca83f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5ecaacb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5ecad594-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5ecaff24-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5ecb2800-6b31-11ec-b3df-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5ecb50dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5ecb79b8-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5ecba33e-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5ecbcc24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5ecbf4ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5ecc1dbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5ecc46fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5ecc6fc6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5ecc98a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5eccc282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96Q40 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5eccec8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5ecd1552-6b31-11ec-b3df-0242ac110002 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5ecd3e24-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5ecd67b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5ecd90a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5ecdb96c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5ecde23e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5ece0b88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5ece345a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5ece5db8-6b31-11ec-b3df-0242ac110002 UniProtKB:O15264 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.18']} DrugCentral uuid:5ece868a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5eceb0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5ecedacc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5ecf03a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.17']} DrugCentral uuid:5ecf2c84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5ecf55ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5ecf7e82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5ecfa74a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5ecfd012-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5ecff98e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5ed0227e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.18']} DrugCentral uuid:5ed04b5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5ed07558-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5ed09e2a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5ed0c7e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5ed0f0d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5ed119fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P49336 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:5ed142d0-6b31-11ec-b3df-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5ed16bac-6b31-11ec-b3df-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5ed1947e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5ed1bdaa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00526 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5ed1e67c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:5ed20f58-6b31-11ec-b3df-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5ed2382a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:5ed26480-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5ed28d52-6b31-11ec-b3df-0242ac110002 UniProtKB:P00520 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:5ed2b624-6b31-11ec-b3df-0242ac110002 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5ed2ded8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5ed3080e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVW4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Cyclin-dependent kinase-like 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:5ed330d6-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5ed359b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5ed382e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5ed3abb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.57']} DrugCentral uuid:5ed3d48c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:5ed3fd5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:5ed42842-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5ed452ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:5ed47b9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5ed4a47a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:5ed4ce96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5ed4f772-6b31-11ec-b3df-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5ed52044-6b31-11ec-b3df-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5ed54934-6b31-11ec-b3df-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5ed572f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5GIT4 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5ed59bbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P10398 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase A-Raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5ed5c5d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8T9Z7 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5ed5efe2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35917 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5ed61b20-6b31-11ec-b3df-0242ac110002 UniProtKB:P05622 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:5ed643fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:5ed66cce-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5ed6960e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28028 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5ed6becc-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5ed6e7a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5ed71084-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:2459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:5ed739a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QNF7 biolink:molecularly_interacts_with DrugCentral:2463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5ed7626e-6b31-11ec-b3df-0242ac110002 UniProtKB:P09250 biolink:molecularly_interacts_with DrugCentral:2463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorivudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5ed78b22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XZT6 biolink:molecularly_interacts_with DrugCentral:2463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorivudine targets Kinase (Deoxynucleoside kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:5ed7b3f4-6b31-11ec-b3df-0242ac110002 UniProtKB:O00142 biolink:molecularly_interacts_with DrugCentral:2463 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sorivudine targets Kinase (Thymidine kinase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5ed7df6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5ed80872-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5ed8314e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:5ed85a3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5ed8839c-6b31-11ec-b3df-0242ac110002 UniProtKB:P54833 biolink:molecularly_interacts_with DrugCentral:2464 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5ed8ac82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.413']} DrugCentral uuid:5ed8da36-6b31-11ec-b3df-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:5ed8da36-6b31-11ec-b3df-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:5ed90d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5ed90d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sparfloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5ed93c56-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A7S3 biolink:molecularly_interacts_with DrugCentral:2468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spectinomycin targets Cytosolic other (30S ribosomal protein S12) DrugCentral uuid:5ed960c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:2469 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiclomazine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:5ed989a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5ed9b62c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:5ed9dfb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:5eda0884-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5eda317e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.65']} DrugCentral uuid:5eda5ab4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5eda83ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:5edaac8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5edad674-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5edaff50-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5edb2822-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.92']} DrugCentral uuid:5edb511c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5edb7be2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.322']} DrugCentral uuid:5edba55e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5edbce30-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5edbf70c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5edc202e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:5edc4a4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5edc72fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5edc9bda-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.297']} DrugCentral uuid:5edcc524-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5edceefa-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5edd17d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:5edd41b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5edd6d12-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:5edd95ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5eddbec0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5edde800-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5ede10c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5ede39ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5ede6276-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.87']} DrugCentral uuid:5ede8bc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5edeb4a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:5edeecdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5edeecdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5edeecdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5edeecdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5edeecdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5edf56b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5edf56b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5edf56b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5edf56b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5edfb504-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5edfb504-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5edfb504-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5edfb504-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5edfb504-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5ee01670-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5ee01670-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5ee01670-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5ee05f18-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:5ee05f18-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:5ee05f18-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:5ee0af22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5ee0af22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5ee0af22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5ee0af22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5ee0af22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BLD9 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5ee10a1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P02665 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Unclassified (Beta-casein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:5ee1330c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5ee15d00-6b31-11ec-b3df-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:2470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spiperone targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5ee18654-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spirapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5ee1af1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:2474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spirapril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.17']} DrugCentral uuid:5ee1d7ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.227']} DrugCentral uuid:5ee2012e-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:5ee22622-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone is antagonist of Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.884']} DrugCentral uuid:5ee24ee0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5ee277a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.029']} DrugCentral uuid:5ee2a070-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5ee2cac8-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:5ee2f692-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5ee3223e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.663']} DrugCentral uuid:5ee34d86-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2475 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spironolactone targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:5ee376e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.033']} DrugCentral uuid:5ee39fa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.327']} DrugCentral uuid:5ee3c87e-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:5ee3f164-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:5ee4164e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.948']} DrugCentral uuid:5ee43f20-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.319']} DrugCentral uuid:5ee467e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:5ee490e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stanozolol targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.316']} DrugCentral uuid:5ee4bdc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:2478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stavudine targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:5ee4e3b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stavudine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5ee50c5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2478 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stavudine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5ee5359c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stiripentol targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:5ee55a18-6b31-11ec-b3df-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:2480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stiripentol targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5ee582b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stiripentol targets Enzyme (Cytochrome P450 1A2) DrugCentral uuid:5ee5a72a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stiripentol targets Enzyme (Cytochrome P450 2C19) DrugCentral uuid:5ee5cbce-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WH62 biolink:molecularly_interacts_with DrugCentral:2481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 streptomycin targets Ribosomal protein (30S ribosomal protein S12) DrugCentral uuid:5ee5f05e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:5ee6193a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:5ee6420c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5ee66c1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:5ee69680-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5ee6c72c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5ee6c72c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5ee6c72c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5ee70886-6b31-11ec-b3df-0242ac110002 UniProtKB:P07727 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:5ee7325c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYW0 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine targets GPCR (Taste receptor type 2 member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5ee75b2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P59540 biolink:molecularly_interacts_with DrugCentral:2484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 strychnine is agonist of GPCR (Taste receptor type 2 member 46) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.367']} DrugCentral uuid:5ee783e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:2487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 succinic acid targets Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5ee7ad04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BXA5 biolink:molecularly_interacts_with DrugCentral:2487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 succinic acid is agonist of GPCR (Succinate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5ee7d6da-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5ee80f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:5ee80f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:5ee80f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:5ee80f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:5ee80f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2489 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suxamethonium is agonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:5ee85fce-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:5ee88878-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5ee8b12c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.301']} DrugCentral uuid:5ee8dae4-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:5ee90410-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:5ee92d0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5ee9613a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:5ee9613a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:5ee9613a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:5ee9613a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.7']} DrugCentral uuid:5ee9ae2e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:5ee9d700-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:2491 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sufentanil targets Unclassified (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5ee9ffd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00807 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5eea2b38-6b31-11ec-b3df-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam is inhibitor of Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5eea569e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:5eea8056-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD63 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5eeaaa22-6b31-11ec-b3df-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5eead3b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P13661 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase OXA-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5eeafc70-6b31-11ec-b3df-0242ac110002 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5eeb2538-6b31-11ec-b3df-0242ac110002 UniProtKB:A1E3K9 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5eeb4e6e-6b31-11ec-b3df-0242ac110002 UniProtKB:A8RR46 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:5eeb7736-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6JP75 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Carbapenem-hydrolizing beta-lactamase SFC-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5eeb9fd6-6b31-11ec-b3df-0242ac110002 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5eebc8b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50H31 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Unclassified (Class D beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5eebf2ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7X575 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5eec1c72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0VTR6 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:5eec451c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0VTR8 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5eec6dee-6b31-11ec-b3df-0242ac110002 UniProtKB:D5HSX5 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5eec9760-6b31-11ec-b3df-0242ac110002 UniProtKB:P83111 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Serine beta-lactamase-like protein LACTB, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:5eecc01e-6b31-11ec-b3df-0242ac110002 UniProtKB:P62594 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5eece8e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0VTS0 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (ADC-18 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.93']} DrugCentral uuid:5eed11a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00809 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5eed3ad0-6b31-11ec-b3df-0242ac110002 UniProtKB:D2SSQ3 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5eed63b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3SAW3 biolink:molecularly_interacts_with DrugCentral:2492 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5eed8d00-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.819']} DrugCentral uuid:5eedb5b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.155']} DrugCentral uuid:5eeddf58-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.125']} DrugCentral uuid:5eee096a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.697']} DrugCentral uuid:5eee3278-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:5eee5c30-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.716']} DrugCentral uuid:5eee850c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.836']} DrugCentral uuid:5eeeadf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.786']} DrugCentral uuid:5eeed7be-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.977']} DrugCentral uuid:5eef014e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.053']} DrugCentral uuid:5eef2a34-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.142']} DrugCentral uuid:5eef531a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.258']} DrugCentral uuid:5eef7c0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.727']} DrugCentral uuid:5eeff70c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.144']} DrugCentral uuid:5ef023da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:5ef04d9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:5ef0772c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.828']} DrugCentral uuid:5ef0a04e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:5ef0c4de-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:5ef0ee3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5ef116fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:5ef13fe0-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:5ef16a24-6b31-11ec-b3df-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5ef1930a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.431']} DrugCentral uuid:5ef1bbf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.738']} DrugCentral uuid:5ef1e4e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5ef20dee-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5ef236fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.782']} DrugCentral uuid:5ef25fd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5ef28878-6b31-11ec-b3df-0242ac110002 UniProtKB:P40925 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Malate dehydrogenase cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5ef2b1ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:2495 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5ef2da6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfacetamide targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:5ef3038e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfacetamide is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:5ef32814-6b31-11ec-b3df-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:2497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfacetamide targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5ef353f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q25704 biolink:molecularly_interacts_with DrugCentral:2499 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfacytine is inhibitor of Kinase (7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase; Dihydropteroate synthetase) DrugCentral uuid:5ef37878-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5ef3a154-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5ef3ca44-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08210 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) DrugCentral uuid:5ef3ef42-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:5ef413b4-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:5ef43c54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZV3 biolink:molecularly_interacts_with DrugCentral:2500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ef4654e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadimethoxine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.206']} DrugCentral uuid:5ef48efc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadimidine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:5ef4b364-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:2502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadimidine targets Enzyme (Lactoylglutathione lyase) DrugCentral uuid:5ef4d7f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q25704 biolink:molecularly_interacts_with DrugCentral:2503 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadoxine is inhibitor of Kinase (7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase; Dihydropteroate synthetase) DrugCentral uuid:5ef4fe28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IAU3 biolink:molecularly_interacts_with DrugCentral:2503 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadoxine targets Unclassified (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.14']} DrugCentral uuid:5ef5284e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:2504 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaethidole targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5ef55152-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaguanidine targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5ef581cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:2505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaguanidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:5ef581cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:2505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaguanidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:5ef581cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35030 biolink:molecularly_interacts_with DrugCentral:2505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaguanidine targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:5ef5c3b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2510 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamerazine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:5ef5e84c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfameter is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:5ef60cdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethizole is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:5ef6313a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08192 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole targets Enzyme (Bifunctional protein FolC) DrugCentral uuid:5ef6567e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole is inhibitor of Enzyme (Dihydropteroate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5ef67f50-6b31-11ec-b3df-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5ef6a804-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5ef6d0d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:2514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfamethoxazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5ef6fb24-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2517 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfalene is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:5ef71fa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5ef7487c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5ef7725c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5ef79ba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5ef7c48c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:5ef7ed72-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:5ef81202-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5ef83b60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5ef864aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5ef88dcc-6b31-11ec-b3df-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5ef8b75c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5ef8e0e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5ef909c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5ef9329a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:5ef95bda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5ef984ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5ef9ad7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ef9d632-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:5ef9ffb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5efa28b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:5efa518e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5efa7a88-6b31-11ec-b3df-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5efaa594-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5eface70-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5efaf74c-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5efb2028-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:5efb495e-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5efb7244-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:5efb9cf6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5efbc690-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5efbef6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00921 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5efc1852-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5efc4138-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5efc6b7c-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfanilamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5efc9458-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaphenazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5efcbd2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfaphenazole is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:5efce1a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfapyridine is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:5efd0672-6b31-11ec-b3df-0242ac110002 UniProtKB:Q49184 biolink:molecularly_interacts_with DrugCentral:2524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfapyridine targets Enzyme (Dihydropteroate synthase type-1) DrugCentral uuid:5efd2ae4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5efd53c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5efd7c74-6b31-11ec-b3df-0242ac110002 UniProtKB:P24752 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Acetyl-CoA acetyltransferase, mitochondrial) DrugCentral uuid:5efda1b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:5efdc652-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPY5 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Transporter (Cystine/glutamate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:5efdef1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5efe186e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.707']} DrugCentral uuid:5efe41f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.628']} DrugCentral uuid:5efe6ac6-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.533']} DrugCentral uuid:5efe93ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine is inhibitor of Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5efebc88-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.768']} DrugCentral uuid:5efee5b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.198']} DrugCentral uuid:5eff125a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:5eff125a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:5eff4162-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5eff6a3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfasalazine targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5eff93f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfathiazole is inhibitor of Enzyme (Dihydropteroate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5effbdb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:2527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfathiazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.161']} DrugCentral uuid:5effe676-6b31-11ec-b3df-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:2527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfathiazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:5f00106a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25084 biolink:molecularly_interacts_with DrugCentral:2527 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfathiazole targets Unclassified (Transcriptional activator protein LasR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5f003a40-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfinpyrazone targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:5f005eb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:2528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfinpyrazone targets GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5f0087ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:2528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfinpyrazone is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5f00b0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:2528 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfinpyrazone targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5f00d996-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5f01025e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08210 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) DrugCentral uuid:5f0126ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:5f014bf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:5f0174b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:5f019d7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:2529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfafurazole targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:5f01c64e-6b31-11ec-b3df-0242ac110002 UniProtKB:O60760 biolink:molecularly_interacts_with DrugCentral:2531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfobromophthalein targets Enzyme (Hematopoietic prostaglandin D synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5f01f10a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulforidazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.611']} DrugCentral uuid:5f021c16-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2532 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulforidazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:5f0244f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C0X1 biolink:molecularly_interacts_with DrugCentral:2533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesulfone is inhibitor of Enzyme (Dihydropteroate synthase 1) DrugCentral uuid:5f02696e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:2533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesulfone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) DrugCentral uuid:5f028e62-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:5f02b72a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5f02e01a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5f0308d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5f033236-6b31-11ec-b3df-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.08']} DrugCentral uuid:5f035aea-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (72 kDa type IV collagenase) DrugCentral uuid:5f037f70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:5f03a842-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.362']} DrugCentral uuid:5f03d3da-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5f03fda6-6b31-11ec-b3df-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5f0426f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5f045008-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.06']} DrugCentral uuid:5f0478d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:2534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulindac targets Unclassified (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5f04a1b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5f04ca88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.307']} DrugCentral uuid:5f04f440-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.177']} DrugCentral uuid:5f051d1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.857']} DrugCentral uuid:5f054616-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.508']} DrugCentral uuid:5f056efc-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.224']} DrugCentral uuid:5f0598e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.146']} DrugCentral uuid:5f05c1cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.606']} DrugCentral uuid:5f05eabc-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.053']} DrugCentral uuid:5f061398-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.965']} DrugCentral uuid:5f063cf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.009']} DrugCentral uuid:5f0665d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.196']} DrugCentral uuid:5f068ecc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.492']} DrugCentral uuid:5f06b7a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.426']} DrugCentral uuid:5f06e142-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5f070a28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:5f0732f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.679']} DrugCentral uuid:5f075bd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5f07878c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.141']} DrugCentral uuid:5f07b0cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.645']} DrugCentral uuid:5f07d99e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suloctidil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5f0803ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:5f082cc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.121']} DrugCentral uuid:5f08559a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5f087e76-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5f08a7f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:5f08d0ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5f08faea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5f0923da-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:5f094de2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:5f0976d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5f09a012-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:5f09c902-6b31-11ec-b3df-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:5f09f242-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:5f0a1ba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5f0a447c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5f0a6e16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GJU1 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5f0a96e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:5f0ac064-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:5f0ae940-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5f0b12da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:5f0b3bc0-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5f0b649c-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5f0b8d64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:5f0bb6ae-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5f0bdf94-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5f0c087a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:5f0c3246-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:5f0c6b08-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5f0c6b08-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5f0c6b08-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5f0c6b08-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5f0c6b08-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5f0cc3a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:5f0cedb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5f0d1698-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2537 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulpiride targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:5f0d3f74-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5f0d685a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.46']} DrugCentral uuid:5f0d9186-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone targets GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.111']} DrugCentral uuid:5f0dba6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5f0de352-6b31-11ec-b3df-0242ac110002 UniProtKB:P35375 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5f0e0c2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30557 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:5f0e355a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34980 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.38']} DrugCentral uuid:5f0e5e22-6b31-11ec-b3df-0242ac110002 UniProtKB:P70597 biolink:molecularly_interacts_with DrugCentral:2538 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulprostone is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5f0e86ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5f0eb052-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5f0edc94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:5f0f05ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:5f0f2e92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5f0f5930-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:5f0f8216-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5f0faaf2-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:5f0fd3ce-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.91']} DrugCentral uuid:5f0ffe76-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:5f102748-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5f105024-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5f107900-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5f10a2a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:5f10cb94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5f10f466-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2540 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultiame targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:5f111d24-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2541 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultopride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.571']} DrugCentral uuid:5f114696-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2541 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sultopride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5f116f72-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5f119844-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5f11c18e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:5f11ea4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5f12131e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5f123c22-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5f1265c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:5f128e8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:5f12b742-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5f12dff6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:5f13097c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:5f133230-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5f135b16-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5f1383ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5f13acf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P79400 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5f13d5aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:5f13ff62-6b31-11ec-b3df-0242ac110002 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:5f142834-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5f1453cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5f147c80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N2B7 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:5f14a552-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8MI13 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan targets Unclassified (5-hydroxytryptamine 1D receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:5f14cec4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:2543 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sumatriptan is agonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5f14f7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5f15205e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5f15491c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:5f157266-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.12']} DrugCentral uuid:5f159b2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:5f15c3f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.68']} DrugCentral uuid:5f15ed54-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5f161748-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5f16415a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5f166a22-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5f1692ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5f16bc8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.66']} DrugCentral uuid:5f16e5d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5f170ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5f1737b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5f176102-6b31-11ec-b3df-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:5f1789ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.23']} DrugCentral uuid:5f17b2ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:5f17dc9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5f180774-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5f18303c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5f18590e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5f188262-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:5f18ab34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:5f18d406-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5f18fce2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:5f192618-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5f194efe-6b31-11ec-b3df-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5f1977d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5f19a0a2-6b31-11ec-b3df-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5f19cc8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:5f19f5c0-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5f1a1e88-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5f1a4746-6b31-11ec-b3df-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5f1a70cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5f1a99a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:5f1ac266-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5f1aeba6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5f1b1496-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:5f1b3d72-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5f1b663a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5f1b8fde-6b31-11ec-b3df-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5f1bb89c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5f1be16e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5f1c0b44-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5f1c34c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5f1c5e28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5f1c8704-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00535 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent-like kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5f1cafe0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5f1cd920-6b31-11ec-b3df-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5f1d031e-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5f1d2be6-6b31-11ec-b3df-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5f1d54b8-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5f1d8154-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5f1daa8a-6b31-11ec-b3df-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5f1dd352-6b31-11ec-b3df-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5f1dfca6-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5f1e256e-6b31-11ec-b3df-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5f1e4e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5f1e771c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5f1ea08e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:5f1ec94c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5f1ef214-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:5f1f1af0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5f1f45a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5f1f6e6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5f1f9732-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5f1fbffa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:5f1fe98a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5f201342-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.26']} DrugCentral uuid:5f203c00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P1W9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase pim-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5f206536-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5f208e08-6b31-11ec-b3df-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5f20b6d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5f20dfac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2H1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 38-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5f210996-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:5f21325e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:5f215b3a-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5f218402-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:5f21ad88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5f21d650-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5f21ff40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:5f2227fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:5f225134-6b31-11ec-b3df-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5f227a06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:5f22a2c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:5f22cba0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:5f22f6de-6b31-11ec-b3df-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5f231fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5f23490e-6b31-11ec-b3df-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5f23728a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:5f239b48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:5f23c442-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5f23ee4a-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:5f241870-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5f244142-6b31-11ec-b3df-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5f246a0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5f249304-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5f24bce4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5f24e5c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JI10 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5f250e92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3U3Q1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5f253764-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:5f2560c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5f25899e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5f25b270-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:5f25db2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:5f2604aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5f262e08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:5f2656d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:5f268092-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5f26aa0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31751 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (RAC-beta serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5f26d2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5f26fba8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:5f2724de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5f274da6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5f27768c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5f279f72-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5f27c8f8-6b31-11ec-b3df-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:5f27f1de-6b31-11ec-b3df-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5f281baa-6b31-11ec-b3df-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5f284454-6b31-11ec-b3df-0242ac110002 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5f286efc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5f2897c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07002 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 18) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5f28c096-6b31-11ec-b3df-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:5f28e97c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5f2912bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:5f293b84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5f296456-6b31-11ec-b3df-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5f298ddc-6b31-11ec-b3df-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:5f29b6ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5f29e016-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:5f2a08e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N752 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform alpha-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5f2a3322-6b31-11ec-b3df-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5f2a5c3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P78368 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5f2a8502-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5f2aaf00-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5f2ad82c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:5f2b00ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86UE8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase tousled-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5f2b29b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5f2b5298-6b31-11ec-b3df-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5f2b7c14-6b31-11ec-b3df-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5f2ba4e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5f2bcdae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5f2bf680-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5f2c2178-6b31-11ec-b3df-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5f2c4a54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5f2c7330-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5f2c9c70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:5f2cc542-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5f2cee14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5f2d16d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:5f2d3ff4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5f2d68bc-6b31-11ec-b3df-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5f2d917a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5f2dba4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5f2de54e-6b31-11ec-b3df-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5f2e1172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5f2e3a6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:5f2e633e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:5f2e8cc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5f2eb5a0-6b31-11ec-b3df-0242ac110002 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:5f2ede68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:5f2f0730-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5f2f3070-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5f2f5938-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5f2f8200-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5f2fac1c-6b31-11ec-b3df-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:5f2fd84a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5f300414-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5f302dcc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5f305752-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:5f308010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5f30a950-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDC3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase BRSK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5f30d22c-6b31-11ec-b3df-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5f30fb58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5f31242a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:5f314cfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5f3175b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:5f31a3a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:5f31cc68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16566 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type IV) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5f31f530-6b31-11ec-b3df-0242ac110002 UniProtKB:P11799 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5f321eac-6b31-11ec-b3df-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5f32477e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5f32705a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5f329922-6b31-11ec-b3df-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:5f32c258-6b31-11ec-b3df-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5f32eb20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCP0 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform gamma-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5f3313f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5f333ce2-6b31-11ec-b3df-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5f336988-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5f339246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NEV4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin-IIIa) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5f33bb04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5f33e3cc-6b31-11ec-b3df-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5f340d16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IWQ3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase BRSK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5f343714-6b31-11ec-b3df-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5f345ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:5f34891c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5f34b1e4-6b31-11ec-b3df-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:5f34dac0-6b31-11ec-b3df-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5f350392-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5f352e26-6b31-11ec-b3df-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:5f3557b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5f3580f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5f35a9c8-6b31-11ec-b3df-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5f35d312-6b31-11ec-b3df-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5f35fbd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:5f3624a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5f364d60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:5f367696-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5f369f7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:5f36c844-6b31-11ec-b3df-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5f36f116-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5f371c36-6b31-11ec-b3df-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5f374508-6b31-11ec-b3df-0242ac110002 UniProtKB:P80370 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Unclassified (Protein delta homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:5f376e5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5f37979c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:5f37c06e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5f37e922-6b31-11ec-b3df-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5f3811f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:5f383ce2-6b31-11ec-b3df-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5f3866cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5f388f9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5f38b85c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:5f38e3a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5f390eec-6b31-11ec-b3df-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5f3937be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:5f396090-6b31-11ec-b3df-0242ac110002 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5f3989d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5f39b2ac-6b31-11ec-b3df-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5f39db6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:5f3a0450-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5f3a2d90-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5f3a5658-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15208 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5f3a7f16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5f3aa978-6b31-11ec-b3df-0242ac110002 UniProtKB:O95747 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase OSR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5f3ad29a-6b31-11ec-b3df-0242ac110002 UniProtKB:O43172 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Nuclear other (U4/U6 small nuclear ribonucleoprotein Prp4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5f3afb6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:5f3b243e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.23']} DrugCentral uuid:5f3b4d7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5f3b7650-6b31-11ec-b3df-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:5f3b9fcc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5f3bc89e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:5f3bf206-6b31-11ec-b3df-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5f3c1bc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5f3c449a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:5f3c6d62-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5f3c97ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:5f3cc096-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5f3ce972-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:5f3d1244-6b31-11ec-b3df-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5f3d3cc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5f3d6596-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5f3d8e72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5f3db79e-6b31-11ec-b3df-0242ac110002 UniProtKB:P42679 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Megakaryocyte-associated tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5f3de05c-6b31-11ec-b3df-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5f3e0938-6b31-11ec-b3df-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5f3e320a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5f3e5c8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:5f3e855c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5f3eaec4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRH2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (SNF-related serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5f3ed796-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:5f3f00c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:5f3f2980-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:5f3f539c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5f3f7c6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5f3fa5a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:5f3fce80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H8M2 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Unclassified (Bromodomain-containing protein 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.77']} DrugCentral uuid:5f3ff75c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5f402254-6b31-11ec-b3df-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.509']} DrugCentral uuid:5f404d7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5f407664-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.229']} DrugCentral uuid:5f409f4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:2544 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sunitinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.959']} DrugCentral uuid:5f40c876-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5f40f170-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suprofen is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5f411a1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2546 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suprofen targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.347']} DrugCentral uuid:5f4142f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P47872 biolink:molecularly_interacts_with DrugCentral:2548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secretin human is agonist of GPCR (Secretin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5f416c04-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5f4194c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:5f41bd6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.523']} DrugCentral uuid:5f41e63e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.954']} DrugCentral uuid:5f42108c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:5f423972-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04844 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Acetylcholine receptor subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:5f426244-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5f428b0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5f42b492-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:5f42dd32-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5f4305e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5f432f26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:5f4357e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:5f438098-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5f43a956-6b31-11ec-b3df-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5f43d37c-6b31-11ec-b3df-0242ac110002 UniProtKB:P32738 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Choline O-acetyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:5f43fc8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5f442638-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ERZ4 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:5f444f3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5f4478c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03311 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5f44a20c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01984 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Histamine N-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5f44cb38-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5f44f400-6b31-11ec-b3df-0242ac110002 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5f451d0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.61']} DrugCentral uuid:5f4549aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:5f4549aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13224 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:5f45824e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5f45824e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12879 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Ion channel (Glutamate NMDA receptor; GRIN1/GRIN2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5f45c894-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:5f45c894-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:5f45c894-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:5f45c894-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:5f45c894-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:5f46229e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.91']} DrugCentral uuid:5f464c38-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:2551 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrine is inhibitor of Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.301']} DrugCentral uuid:5f467500-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5f469dd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5f46c690-6b31-11ec-b3df-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:5f46efa8-6b31-11ec-b3df-0242ac110002 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Cytokine (Interferon gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.22']} DrugCentral uuid:5f47187a-6b31-11ec-b3df-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.398']} DrugCentral uuid:5f47412e-6b31-11ec-b3df-0242ac110002 UniProtKB:P60568 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Cytokine (Interleukin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.72']} DrugCentral uuid:5f4769e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48454 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:5f47966a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:5f47bf32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5f47e7f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P68106 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5f48111c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13451 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5f483a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15393 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Nuclear other (Splicing factor 3B subunit 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5f4862f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96AY3 biolink:molecularly_interacts_with DrugCentral:2552 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacrolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.02']} DrugCentral uuid:5f488bb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5f48b4f0-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5f48ddd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5f49069e-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:5f492f52-6b31-11ec-b3df-0242ac110002 UniProtKB:O54735 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5f495950-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28156 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:5f49822c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11541 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5f49be22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5f49be22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5f49be22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5f49be22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5f49be22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5f49be22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13956 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:5f4a3604-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5f4a3604-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5f4a3604-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5f4a3604-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5f4a3604-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5f4a3604-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95142 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Phosphodiesterase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:5f4a9b9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:2553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tadalafil targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4afda0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2556 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talbutal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f4bc2c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5f4beb7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5f4c1442-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5f4c38e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5f4c61f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5f4c8af8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talinolol targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:5f4cb3ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.309']} DrugCentral uuid:5f4cdc92-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.915']} DrugCentral uuid:5f4d06f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5f4d2fb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:5f4d5884-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:5f4d825a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5f4dabae-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.695']} DrugCentral uuid:5f4dd462-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:5f4dfd34-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5f4e25f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:5f4e4f5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:5f4e7fde-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5f4e7fde-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5f4e7fde-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2558 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talipexole targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5f4ec0a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34981 biolink:molecularly_interacts_with DrugCentral:2560 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 taltirelin is agonist of GPCR (Thyrotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:5f4eeab4-6b31-11ec-b3df-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.807']} DrugCentral uuid:5f4f1390-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.001']} DrugCentral uuid:5f4f3c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5f4f6570-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.357']} DrugCentral uuid:5f4f8e4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.146']} DrugCentral uuid:5f4fb728-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.372']} DrugCentral uuid:5f4fdff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.335']} DrugCentral uuid:5f500926-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5f5031f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.139']} DrugCentral uuid:5f505c14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5f50850e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5f50aec6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.301']} DrugCentral uuid:5f50d798-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5f510088-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.907']} DrugCentral uuid:5f51296e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.836']} DrugCentral uuid:5f5153b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.158']} DrugCentral uuid:5f517cac-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.863']} DrugCentral uuid:5f51a588-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.877']} DrugCentral uuid:5f51ce6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.618']} DrugCentral uuid:5f51f79a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:5f522120-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.794']} DrugCentral uuid:5f5249e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:5f527436-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.034']} DrugCentral uuid:5f529e34-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.167']} DrugCentral uuid:5f52c706-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.557']} DrugCentral uuid:5f52efec-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.201']} DrugCentral uuid:5f53192c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.173']} DrugCentral uuid:5f534208-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.731']} DrugCentral uuid:5f536ada-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.658']} DrugCentral uuid:5f5393a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.238']} DrugCentral uuid:5f53bcce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.835']} DrugCentral uuid:5f53e5a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.858']} DrugCentral uuid:5f540f1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.679']} DrugCentral uuid:5f5437e4-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:5f5461c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.407']} DrugCentral uuid:5f548aa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.611']} DrugCentral uuid:5f54b37c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.204']} DrugCentral uuid:5f54dc76-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5f5505b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5f552e74-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.328']} DrugCentral uuid:5f555840-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:5f558176-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99527 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (G-protein coupled estrogen receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.5']} DrugCentral uuid:5f55aa3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P62508 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Estrogen-related receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5f55d306-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.449']} DrugCentral uuid:5f55fbd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.069']} DrugCentral uuid:5f56266c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.095']} DrugCentral uuid:5f5650f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.923']} DrugCentral uuid:5f5679d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:5f56a29a-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.038']} DrugCentral uuid:5f56cbda-6b31-11ec-b3df-0242ac110002 UniProtKB:P11474 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Nuclear hormone receptor (Steroid hormone receptor ERR1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5f56f498-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.913']} DrugCentral uuid:5f571dc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.821']} DrugCentral uuid:5f5747cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30411 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.919']} DrugCentral uuid:5f57712a-6b31-11ec-b3df-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.533']} DrugCentral uuid:5f5799de-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.604']} DrugCentral uuid:5f57c2b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.761']} DrugCentral uuid:5f57eb96-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.419']} DrugCentral uuid:5f581698-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.515']} DrugCentral uuid:5f583f4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.587']} DrugCentral uuid:5f58681e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5f589154-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5f58ba30-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5f58e2ee-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.061']} DrugCentral uuid:5f590bac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BY08 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Emopamil-binding protein-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.55']} DrugCentral uuid:5f5938c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBM7 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Anti-estrogen binding site (AEBS)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5f5938c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBM7 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Enzyme (Anti-estrogen binding site (AEBS)) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:5f596ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2561 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamoxifen targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5f599766-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5f59c038-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.87']} DrugCentral uuid:5f59ea90-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5f5a1376-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:5f5a3c48-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.54']} DrugCentral uuid:5f5a659c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:5f5a8e78-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5f5ab754-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.24']} DrugCentral uuid:5f5ae044-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:5f5b097a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.52']} DrugCentral uuid:5f5b3256-6b31-11ec-b3df-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:5f5b5b3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:5f5b83fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:5f5bae48-6b31-11ec-b3df-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:5f5be278-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5f5be278-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5f5be278-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5f5be278-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamsulosin targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5f5c2f4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tandospirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5f5c58ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tandospirone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:5f5c81a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2563 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tandospirone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:5f5caaa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:2571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5f5cd3ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:2571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5f5cfdca-6b31-11ec-b3df-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:2571 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5f5d267e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00808 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:5f5d4f32-6b31-11ec-b3df-0242ac110002 UniProtKB:P00807 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.527']} DrugCentral uuid:5f5d7930-6b31-11ec-b3df-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam is inhibitor of Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.602']} DrugCentral uuid:5f5da338-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:5f5dcc0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59401 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5f5df4c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD63 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:5f5e1e3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10424 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.524']} DrugCentral uuid:5f5e46f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q46991 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (IMI-1; IMI-1 carbapenemase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5f5e6fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5f5e98a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6W9J1 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5f5ec1d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:5f5eea90-6b31-11ec-b3df-0242ac110002 UniProtKB:P94958 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5f5f134e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05193 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:5f5f3c16-6b31-11ec-b3df-0242ac110002 UniProtKB:A4KCT8 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5f5f6588-6b31-11ec-b3df-0242ac110002 UniProtKB:A1E3K9 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5f5f8e46-6b31-11ec-b3df-0242ac110002 UniProtKB:A8RR46 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5f5fb704-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6JP75 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Carbapenem-hydrolizing beta-lactamase SFC-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5f5fe08a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9F663 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Carbepenem-hydrolyzing beta-lactamase KPC) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:5f600948-6b31-11ec-b3df-0242ac110002 UniProtKB:A2RP81 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:5f603206-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EXV5 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5f605ace-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD64 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase SHV-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5f6083fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6GWS8 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5f60acae-6b31-11ec-b3df-0242ac110002 UniProtKB:D1MIX9 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase GES-13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5f60d576-6b31-11ec-b3df-0242ac110002 UniProtKB:A0ZX81 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5f60fe52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50H31 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Unclassified (Class D beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5f612922-6b31-11ec-b3df-0242ac110002 UniProtKB:B8R6A5 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5f6151f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2XPY6 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:5f617aa8-6b31-11ec-b3df-0242ac110002 UniProtKB:D2SSQ3 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5f61a370-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3SAW3 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5f61ccd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q670S6 biolink:molecularly_interacts_with DrugCentral:2572 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazobactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5f61f5aa-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5f621e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod targets GPCR (5-hydroxytryptamine receptor 1A) DrugCentral uuid:5f6242da-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5f626be8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod targets GPCR (5-hydroxytryptamine receptor 1D) DrugCentral uuid:5f62906e-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5f62b940-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:2579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tegaserod is partial agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5f62e226-6b31-11ec-b3df-0242ac110002 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:2580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teicoplanin aglycone is inhibitor of Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.78']} DrugCentral uuid:5f630be8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2581 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telithromycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5f6334b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5f635e0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:5f6387ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.31']} DrugCentral uuid:5f63b0d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5f63d992-6b31-11ec-b3df-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:5f64025a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5f642b72-6b31-11ec-b3df-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:5f64544e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2583 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telmisartan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:5f647e6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temazepam targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:5f64aaa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5f64aaa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5f64aaa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2585 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temazepam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5f64e7e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temocapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.444']} DrugCentral uuid:5f6511b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temocapril is inhibitor of Enzyme (Angiotensin-converting enzyme) DrugCentral uuid:5f65362a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5f655ae2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:5f657fea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:5f65a466-6b31-11ec-b3df-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:5f65c8ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O15438 biolink:molecularly_interacts_with DrugCentral:2590 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teniposide targets Transporter (Canalicular multispecific organic anion transporter 2) DrugCentral uuid:5f65ed54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenofovir targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5f66168a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:2592 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenofovir targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5f663f52-6b31-11ec-b3df-0242ac110002 UniProtKB:P03369 biolink:molecularly_interacts_with DrugCentral:2593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenofovir disoproxil targets Polyprotein (Gag-Pol polyprotein) DrugCentral uuid:5f6663ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2593 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenofovir disoproxil is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:5f668836-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2595 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenoxicam targets Enzyme (Prostaglandin G/H synthase 2) DrugCentral uuid:5f66adf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2595 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenoxicam targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.943']} DrugCentral uuid:5f66d6b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.67']} DrugCentral uuid:5f66ff96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.628']} DrugCentral uuid:5f67285e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.388']} DrugCentral uuid:5f6751c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:5f677a8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14534 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5f67a34c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4JEY0 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine is inhibitor of Enzyme (Squalene epoxidase) DrugCentral uuid:5f67c7e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.662']} DrugCentral uuid:5f67f112-6b31-11ec-b3df-0242ac110002 UniProtKB:P52020 biolink:molecularly_interacts_with DrugCentral:2597 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbinafine targets Enzyme (Squalene monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:5f6819f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2598 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbutaline is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5f6842ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2598 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terbutaline targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5f686cb4-6b31-11ec-b3df-0242ac110002 UniProtKB:O00337 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Transporter (Sodium/nucleoside cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.373']} DrugCentral uuid:5f6897b6-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.609']} DrugCentral uuid:5f68c0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.895']} DrugCentral uuid:5f68e978-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.433']} DrugCentral uuid:5f6912f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:5f693d42-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.216']} DrugCentral uuid:5f69661e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.599']} DrugCentral uuid:5f698ef0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.632']} DrugCentral uuid:5f69b844-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.438']} DrugCentral uuid:5f69e102-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.904']} DrugCentral uuid:5f6a09f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:5f6a32ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.862']} DrugCentral uuid:5f6a5ca4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.338']} DrugCentral uuid:5f6a856c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.511']} DrugCentral uuid:5f6aae3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.718']} DrugCentral uuid:5f6ad83c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.504']} DrugCentral uuid:5f6b01b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:5f6b2a94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.362']} DrugCentral uuid:5f6b5370-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:5f6b7cce-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:5f6ba154-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.666']} DrugCentral uuid:5f6bca26-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.963']} DrugCentral uuid:5f6bf2da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5f6c1d14-6b31-11ec-b3df-0242ac110002 UniProtKB:P23711 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Heme oxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5f6c45f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.612']} DrugCentral uuid:5f6c6ea4-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.102']} DrugCentral uuid:5f6c978a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.389']} DrugCentral uuid:5f6cc106-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:5f6ce9ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:5f6d12aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P23711 biolink:molecularly_interacts_with DrugCentral:2599 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terconazole targets Enzyme (Heme oxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5f6d3c58-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.874']} DrugCentral uuid:5f6d6584-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.687']} DrugCentral uuid:5f6d8e60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.252']} DrugCentral uuid:5f6db71e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:5f6ddff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.719']} DrugCentral uuid:5f6e0b10-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.137']} DrugCentral uuid:5f6e33f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:5f6e5cc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5f6e8676-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:5f6eaf48-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.292']} DrugCentral uuid:5f6ed838-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5f6f0196-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5f6f2ac2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.264']} DrugCentral uuid:5f6f53a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.693']} DrugCentral uuid:5f6f7ca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.448']} DrugCentral uuid:5f6fa556-6b31-11ec-b3df-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.07']} DrugCentral uuid:5f6fd06c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.213']} DrugCentral uuid:5f6ff920-6b31-11ec-b3df-0242ac110002 UniProtKB:P51589 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Enzyme (Cytochrome P450 2J2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:5f7021e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5f704aba-6b31-11ec-b3df-0242ac110002 UniProtKB:O95259 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine is blocker of Ion channel (Potassium voltage-gated channel subfamily H member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5f70742c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.734']} DrugCentral uuid:5f709cfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.45']} DrugCentral uuid:5f70c5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5f70f6a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:5f70f6a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:5f70f6a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:5f713894-6b31-11ec-b3df-0242ac110002 UniProtKB:P12746 biolink:molecularly_interacts_with DrugCentral:2600 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terfenadine targets Unclassified (Transcriptional activator protein luxR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:5f716148-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:5f718b64-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5f71b508-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5f71dde4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5f7206ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:5f72306e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5f725936-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5f728262-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.5']} DrugCentral uuid:5f72ab70-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5f72d4b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:5f72fd78-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:5f732672-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5f734f3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5f73792e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5f73a200-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5f73cad2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:5f73f390-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:5f741cf8-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5f7445ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5f746e9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:5f749764-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5f74c0f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terguride is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5f74e9c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2603 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terodiline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5f75139c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.087']} DrugCentral uuid:5f753d54-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:5f75691e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:5f7591dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P25962 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5f75bac2-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tertatolol is antagonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5f75e470-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:2606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testolactone is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5f760d56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5f763632-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.837']} DrugCentral uuid:5f765f18-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:5f768880-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:5f76b148-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5f76da06-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:5f7702e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5f772ef2-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5f775882-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.599']} DrugCentral uuid:5f778136-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5f77ae54-6b31-11ec-b3df-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5f77ae54-6b31-11ec-b3df-0242ac110002 UniProtKB:P31214 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Enzyme (Steroid 5-alpha-reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5f77e2fc-6b31-11ec-b3df-0242ac110002 UniProtKB:O35627 biolink:molecularly_interacts_with DrugCentral:2607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone targets Nuclear hormone receptor (Constitutive androstane receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:5f780be2-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2608 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone undecanoate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:5f7831a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:5f785b1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.018']} DrugCentral uuid:5f7883ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.886']} DrugCentral uuid:5f78ace6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5f78d5cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q27963 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5f7901d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01827 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.12']} DrugCentral uuid:5f792ae0-6b31-11ec-b3df-0242ac110002 UniProtKB:P54219 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine is inhibitor of Transporter (Chromaffin granule amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5f795b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:5f795b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:5f795b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetrabenazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:5f799cd2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5f79c590-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.153']} DrugCentral uuid:5f79ee6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.011']} DrugCentral uuid:5f7a177a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.766']} DrugCentral uuid:5f7a4114-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99250 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5f7a69e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQD0 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (Sodium channel protein type 8 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:5f7a92cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5f7abc84-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.499']} DrugCentral uuid:5f7ae560-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00194 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (cGMP-gated cation channel alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5f7b15f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5f7b15f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5f7b15f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5f7b5f5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5f7b5f5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5f7b5f5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:2610 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5f7b9fe6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A7V8 biolink:molecularly_interacts_with DrugCentral:2611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracycline targets Ribosomal protein (30S ribosomal protein S4) DrugCentral uuid:5f7bc444-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A7X3 biolink:molecularly_interacts_with DrugCentral:2611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracycline targets Ribosomal protein (30S ribosomal protein S9) DrugCentral uuid:5f7be8c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P29475 biolink:molecularly_interacts_with DrugCentral:2612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sapropterin targets Enzyme (Nitric oxide synthase, brain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.95']} DrugCentral uuid:5f7c1232-6b31-11ec-b3df-0242ac110002 UniProtKB:P00439 biolink:molecularly_interacts_with DrugCentral:2612 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sapropterin is activator of Enzyme (Phenylalanine-4-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5f7c3bf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:2615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:5f7c64a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:5f7c8e24-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5f7cb82c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8Z9J9 biolink:molecularly_interacts_with DrugCentral:2615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetroxoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.35']} DrugCentral uuid:5f7ce0fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.301']} DrugCentral uuid:5f7d099e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.432']} DrugCentral uuid:5f7d3298-6b31-11ec-b3df-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5f7d5b42-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5f7d841e-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5f7dacf0-6b31-11ec-b3df-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:5f7dd6b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:2616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thalidomide is modulator of Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.393']} DrugCentral uuid:5f7dff98-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5f7e2892-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is inhibitor of Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.85']} DrugCentral uuid:5f7e518c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:5f7e7c98-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5f7ea588-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5f7ece8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:5f7ef75e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:5f7f20b2-6b31-11ec-b3df-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:5f7f4970-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5f7f74d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:5f7f9e52-6b31-11ec-b3df-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:5f7fc724-6b31-11ec-b3df-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:5f7fefec-6b31-11ec-b3df-0242ac110002 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:5f8018d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:5f804848-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5f804848-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:5f80809c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5f80b4d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5f80b4d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5f80b4d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5f80b4d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5f81099a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:5f81099a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:5f81099a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:5f814a36-6b31-11ec-b3df-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5f8173ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60614 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.25']} DrugCentral uuid:5f819cd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS9 biolink:molecularly_interacts_with DrugCentral:2620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 theophylline targets Unclassified (Transmembrane domain-containing protein TMIGD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.06']} DrugCentral uuid:5f81c678-6b31-11ec-b3df-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.22']} DrugCentral uuid:5f81ef9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.097']} DrugCentral uuid:5f821a1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09508 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial) DrugCentral uuid:5f82406c-6b31-11ec-b3df-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:5f82693e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:5f829206-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AE18 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Methionine aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:5f82bb32-6b31-11ec-b3df-0242ac110002 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5f82eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5f82eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5f82eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:C4PKZ6 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5f833b98-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5f833b98-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5f833b98-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5f833b98-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5f833b98-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5f833b98-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5f833b98-6b31-11ec-b3df-0242ac110002 UniProtKB:F1LCS0 biolink:molecularly_interacts_with DrugCentral:2621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiabendazole is inhibitor of Structural (Tubulin) DrugCentral uuid:5f83a010-6b31-11ec-b3df-0242ac110002 UniProtKB:P15825 biolink:molecularly_interacts_with DrugCentral:2624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamphenicol targets Ribosomal protein (50S ribosomal protein L10) DrugCentral uuid:5f83c5b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamphenicol targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:5f83f04c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10520 biolink:molecularly_interacts_with DrugCentral:2624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamphenicol targets Enzyme (Streptokinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f845172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2626 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamylal is positive allosteric modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5f85113e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.301']} DrugCentral uuid:5f853b78-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5f856468-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:5f858d30-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.155']} DrugCentral uuid:5f85b6de-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5f85e0a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5f860968-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5f863258-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5f865cce-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5f8685a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.602']} DrugCentral uuid:5f86ae86-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5f86d2f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:5f86f7e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:5f871c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M4) DrugCentral uuid:5f8740da-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets GPCR (Muscarinic acetylcholine receptor M5) DrugCentral uuid:5f87656a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:5f878f7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiethylperazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5f87b8bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.221']} DrugCentral uuid:5f87e184-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.912']} DrugCentral uuid:5f880a74-6b31-11ec-b3df-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:5f882f40-6b31-11ec-b3df-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:5f8853c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P20839 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 1) DrugCentral uuid:5f887838-6b31-11ec-b3df-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:5f88a114-6b31-11ec-b3df-0242ac110002 UniProtKB:P12268 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine is inhibitor of Enzyme (Inosine-5'-monophosphate dehydrogenase 2) DrugCentral uuid:5f88c63a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00492 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Enzyme (Hypoxanthine-guanine phosphoribosyltransferase) DrugCentral uuid:5f88ec8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.258']} DrugCentral uuid:5f89155e-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.792']} DrugCentral uuid:5f893e44-6b31-11ec-b3df-0242ac110002 UniProtKB:P26281 biolink:molecularly_interacts_with DrugCentral:2632 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioguanine targets Kinase (2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.75']} DrugCentral uuid:5f897080-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5f897080-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5f897080-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f89e2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:5f8ac0ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63734 biolink:molecularly_interacts_with DrugCentral:2633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiopental is gating inhibitor of Ion channel (Potassium voltage-gated channel subfamily C member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5f8ae960-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioproperazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.347']} DrugCentral uuid:5f8b1250-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioproperazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.921']} DrugCentral uuid:5f8b3c6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) DrugCentral uuid:5f8b60f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5f8b89d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5f8bb28c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.872']} DrugCentral uuid:5f8bdc12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.815']} DrugCentral uuid:5f8c04f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5f8c2dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5f8c56c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.813']} DrugCentral uuid:5f8c7ffa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5f8ca8e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5f8cd1b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.086']} DrugCentral uuid:5f8cfbce-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5f8d255e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5f8d4e62-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:5f8d7734-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5f8da006-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.466']} DrugCentral uuid:5f8dc996-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5f8df3b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5f8e1ca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:5f8e45ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.866']} DrugCentral uuid:5f8e6ed2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5f8e97b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.569']} DrugCentral uuid:5f8ec094-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:5f8eeb00-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.595']} DrugCentral uuid:5f8f1724-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.046']} DrugCentral uuid:5f8f4258-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:5f8f6b34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.796']} DrugCentral uuid:5f8f949c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.963']} DrugCentral uuid:5f8fbd6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.237']} DrugCentral uuid:5f8fe64a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.126']} DrugCentral uuid:5f900f1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.774']} DrugCentral uuid:5f903866-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.751']} DrugCentral uuid:5f906138-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.979']} DrugCentral uuid:5f908a14-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.686']} DrugCentral uuid:5f90b3f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:5f90dfdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.002']} DrugCentral uuid:5f910a84-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:5f9133c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:5f915d5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.712']} DrugCentral uuid:5f91864e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.531']} DrugCentral uuid:5f91af20-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.195']} DrugCentral uuid:5f91d7f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.297']} DrugCentral uuid:5f920128-6b31-11ec-b3df-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5f9229fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:5f9252ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.284']} DrugCentral uuid:5f927bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:5f92a574-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:5f92ce46-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5f92f722-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.76']} DrugCentral uuid:5f931fe0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:5f93497a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:5f937260-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5f93aa5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5f93aa5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5f93aa5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5f93aa5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5f93aa5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5f940ed2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5f940ed2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5f940ed2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5f940ed2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:5f9466e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5f9466e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5f9466e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5f94b6d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5f94b6d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5f94b6d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5f94b6d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5f94b6d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5f9517e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5f9517e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5f9517e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5f956034-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5f956034-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5f956034-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5f95a15c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48542 biolink:molecularly_interacts_with DrugCentral:2637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioridazine is gating inhibitor of Ion channel (G protein-activated inward rectifier potassium channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:5f95ca06-6b31-11ec-b3df-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2638 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiotepa is inhibitor of Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5f95f314-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.292']} DrugCentral uuid:5f961bf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.347']} DrugCentral uuid:5f9646c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.097']} DrugCentral uuid:5f966f92-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.411']} DrugCentral uuid:5f969864-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.387']} DrugCentral uuid:5f96c154-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5f96eac6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.868']} DrugCentral uuid:5f9713a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.681']} DrugCentral uuid:5f973c7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.817']} DrugCentral uuid:5f976636-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.94']} DrugCentral uuid:5f978f58-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5f97b83e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.412']} DrugCentral uuid:5f97e106-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.583']} DrugCentral uuid:5f980b04-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5f983502-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.386']} DrugCentral uuid:5f985de8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.585']} DrugCentral uuid:5f9886ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:5f98b02c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.398']} DrugCentral uuid:5f98d994-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.812']} DrugCentral uuid:5f99027a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.318']} DrugCentral uuid:5f992b56-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:5f9954c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.181']} DrugCentral uuid:5f997d90-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:5f99a676-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.693']} DrugCentral uuid:5f99cf34-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:5f99faae-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.456']} DrugCentral uuid:5f9a2380-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiothixene targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.442']} DrugCentral uuid:5f9a4c8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor alpha) DrugCentral uuid:5f9a7128-6b31-11ec-b3df-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine is agonist of Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5f9a9aa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5f9ac380-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5f9aec52-6b31-11ec-b3df-0242ac110002 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:5f9b1588-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Unclassified (THAP domain-containing protein 1) DrugCentral uuid:5f9b3a0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14174 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Unclassified (Macrophage migration inhibitory factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5f9b63b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P40926 biolink:molecularly_interacts_with DrugCentral:2646 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levothyroxine targets Enzyme (Malate dehydrogenase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.36']} DrugCentral uuid:5f9b8c98-6b31-11ec-b3df-0242ac110002 UniProtKB:P30531 biolink:molecularly_interacts_with DrugCentral:2648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiagabine is inhibitor of Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5f9bb6c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23978 biolink:molecularly_interacts_with DrugCentral:2648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiagabine targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:5f9bdfae-6b31-11ec-b3df-0242ac110002 UniProtKB:P31648 biolink:molecularly_interacts_with DrugCentral:2648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiagabine targets Transporter (Sodium- and chloride-dependent GABA transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:5f9c089e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31651 biolink:molecularly_interacts_with DrugCentral:2648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiagabine targets Transporter (Sodium- and chloride-dependent betaine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5f9c3904-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.04']} DrugCentral uuid:5f9c3904-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.04']} DrugCentral uuid:5f9c3904-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.04']} DrugCentral uuid:5f9c824c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5f9c824c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5f9c824c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2649 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiamenidine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5f9cc2fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2650 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tianeptine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:5f9cec6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiapride targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.077']} DrugCentral uuid:5f9d1536-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiapride targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.108']} DrugCentral uuid:5f9d3e08-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiapride targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.756']} DrugCentral uuid:5f9d66c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiapride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:5f9d913c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiaprofenic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5f9dba0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiaprofenic acid is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5f9de2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.317']} DrugCentral uuid:5f9e0bd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.907']} DrugCentral uuid:5f9e3538-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:5f9e59a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:5f9e7e26-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:5f9ea6e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Enzyme (Steryl-sulfatase) DrugCentral uuid:5f9ecc14-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.123']} DrugCentral uuid:5f9ef4dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tibolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.542']} DrugCentral uuid:5f9f1eb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8XJ01 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin targets Enzyme (Penicillin-binding protein 1A) DrugCentral uuid:5f9f5b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5f9f5b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5f9f5b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5f9f5b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5f9f5b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5f9f5b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5f9f5b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:2656 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticarcillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:5f9fbf16-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:5f9fe7de-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5fa0110a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.845']} DrugCentral uuid:5fa039f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.747']} DrugCentral uuid:5fa06344-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.857']} DrugCentral uuid:5fa08c34-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.767']} DrugCentral uuid:5fa0b5ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.201']} DrugCentral uuid:5fa0deaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P11509 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Cytochrome P450 2A6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5fa10772-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:5fa1310c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine is antagonist of GPCR (P2Y purinoceptor 12) DrugCentral uuid:5fa15588-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.175']} DrugCentral uuid:5fa17e5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine is inhibitor of Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5fa1a72c-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.697']} DrugCentral uuid:5fa1d062-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2657 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticlopidine targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:5fa1f920-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tienilic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.494']} DrugCentral uuid:5fa221fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tilidine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:5fa24ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:2664 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiliquinol targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:5fa27440-6b31-11ec-b3df-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) DrugCentral uuid:5fa298c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13488 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (V-type proton ATPase 116 kDa subunit a isoform 3) DrugCentral uuid:5fa2bd60-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:5fa2e722-6b31-11ec-b3df-0242ac110002 UniProtKB:P50281 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (Matrix metalloproteinase-14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:5fa31152-6b31-11ec-b3df-0242ac110002 UniProtKB:P22894 biolink:molecularly_interacts_with DrugCentral:2666 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiludronic acid targets Enzyme (Neutrophil collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:5fa33a10-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:2672 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tinoridine is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.987']} DrugCentral uuid:5fa362d8-6b31-11ec-b3df-0242ac110002 UniProtKB:O69638 biolink:molecularly_interacts_with DrugCentral:2673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiocarlide targets Enzyme (Epoxide hydrolase EphE; Hydrolase, alpha/beta hydrolase fold family) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:5fa38bb4-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2675 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:5fa3b094-6b31-11ec-b3df-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:2675 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioconazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5fa3d97a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiopronin targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:5fa40260-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:5fa42b32-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:5fa454b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11.1']} DrugCentral uuid:5fa47d94-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:5fa4a670-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:5fa4cf4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:5fa4fb84-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:5fa52762-6b31-11ec-b3df-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2677 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiotropium bromide targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:5fa5505c-6b31-11ec-b3df-0242ac110002 UniProtKB:F1PT23 biolink:molecularly_interacts_with DrugCentral:2678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiquizium targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5fa57a3c-6b31-11ec-b3df-0242ac110002 UniProtKB:F1PWR7 biolink:molecularly_interacts_with DrugCentral:2678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiquizium targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.94']} DrugCentral uuid:5fa5a318-6b31-11ec-b3df-0242ac110002 UniProtKB:F1PGZ2 biolink:molecularly_interacts_with DrugCentral:2678 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiquizium targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:5fa5cc1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14994 biolink:molecularly_interacts_with DrugCentral:2679 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiracizine targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:5fa5f8d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:2680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirofiban is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.959']} DrugCentral uuid:5fa5f8d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:2680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirofiban is inhibitor of Adhesion (Integrin alpha-IIb/beta-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.959']} DrugCentral uuid:5fa62e8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:5fa65880-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine is agonist of GPCR (Alpha-2B adrenergic receptor) DrugCentral uuid:5fa67d2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:5fa6a5e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:5fa6d0a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.58']} DrugCentral uuid:5fa6f97a-6b31-11ec-b3df-0242ac110002 UniProtKB:G3HDX1 biolink:molecularly_interacts_with DrugCentral:2683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tizanidine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:5fa72242-6b31-11ec-b3df-0242ac110002 UniProtKB:O32553 biolink:molecularly_interacts_with DrugCentral:2684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tobramycin targets Enzyme (Macrolide 2'-phosphotransferase II; Macrolide 2'-phosphotransferase II protein MphB; Macrolide 2-phosphotransferase, mph(B)) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['5.824']} DrugCentral uuid:5fa76dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5fa76dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5fa76dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5fa76dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5fa76dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5fa76dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5fa76dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5fa76dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5fa76dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5fa76dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:2686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocainide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:5fa7f032-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2693 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofisopam targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5fa818f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2693 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofisopam targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:5fa841c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazamide targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.292']} DrugCentral uuid:5fa86e86-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) DrugCentral uuid:5fa86e86-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2694 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) DrugCentral uuid:5fa8a004-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:5fa8c908-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:5fa8f1f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:5fa91ade-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:5fa94428-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:5fa974b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5fa974b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5fa974b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:5fa9bd9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5fa9bd9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5fa9bd9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2695 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:5fa9ff6c-6b31-11ec-b3df-0242ac110002 UniProtKB:O35956 biolink:molecularly_interacts_with DrugCentral:2696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolbutamide targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:5faa2866-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61743 biolink:molecularly_interacts_with DrugCentral:2696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolbutamide is blocker of Ion channel (ATP-sensitive inward rectifier potassium channel 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5faa55fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:5faa55fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14654 biolink:molecularly_interacts_with DrugCentral:2696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolbutamide is blocker of Ion channel (Sulfonylurea receptor 1, Kir6.2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.046']} DrugCentral uuid:5faa8ea0-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.69']} DrugCentral uuid:5faab772-6b31-11ec-b3df-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:5faae030-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5fab0998-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13118 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets Nuclear other (Krueppel-like factor 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:5fab32d8-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:5fab5bbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:2697 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolcapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.569']} DrugCentral uuid:5fab84ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5fabaf24-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5fabd80a-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5fac00d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.33']} DrugCentral uuid:5fac2a76-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:2698 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolfenamic acid targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5fac5546-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:5fac7e22-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:5faca6e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5facd048-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.06']} DrugCentral uuid:5facf92e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10145 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin targets Cytokine (Interleukin-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:5fad2214-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2699 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolmetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.667']} DrugCentral uuid:5fad4adc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:2701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolonium targets Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.16']} DrugCentral uuid:5fad7426-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:2701 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolonium targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:5fad9cda-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5fadc69c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5fadef78-6b31-11ec-b3df-0242ac110002 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:5fae1b42-6b31-11ec-b3df-0242ac110002 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5fae457c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toloxatone is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:5fae6e62-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolperisone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.253']} DrugCentral uuid:5fae973e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolperisone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.341']} DrugCentral uuid:5faec0f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P70634 biolink:molecularly_interacts_with DrugCentral:2703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolperisone targets Unclassified (SMR1-alpha3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.685']} DrugCentral uuid:5faee9be-6b31-11ec-b3df-0242ac110002 UniProtKB:P70635 biolink:molecularly_interacts_with DrugCentral:2703 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolperisone targets Unclassified (BetaB2-crystallin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.474']} DrugCentral uuid:5faf1286-6b31-11ec-b3df-0242ac110002 UniProtKB:P14550 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:5faf3bd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:5faf64a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P80276 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5faf8d56-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5fafb68c-6b31-11ec-b3df-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5fafe012-6b31-11ec-b3df-0242ac110002 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:5fb008d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q91WR5 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldo-keto reductase family 1 member C21) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:5fb031a2-6b31-11ec-b3df-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:5fb05a88-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolrestat is inhibitor of Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.509']} DrugCentral uuid:5fb083d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5fb0acb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5fb0d5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.57']} DrugCentral uuid:5fb0feb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.49']} DrugCentral uuid:5fb12850-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:5fb151cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:5fb17aa8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:5fb1a3a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5fb1ce9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5fb1f78a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08911 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:5fb22084-6b31-11ec-b3df-0242ac110002 UniProtKB:P08485 biolink:molecularly_interacts_with DrugCentral:2705 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolterodine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.51']} DrugCentral uuid:5fb249d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is blocker of Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:5fb26fb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:5fb2944c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:5fb2b8d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is inhibitor of Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:5fb2e294-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:5fb30b98-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is inhibitor of Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5fb33492-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:5fb35d64-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5fb387b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5fb3b3b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5fb3dcbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:5fb40598-6b31-11ec-b3df-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:5fb42ee2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:5fb457be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.84']} DrugCentral uuid:5fb480a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:5fb4a958-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.27']} DrugCentral uuid:5fb4d2e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:5fb4fbce-6b31-11ec-b3df-0242ac110002 UniProtKB:P27139 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5fb524a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5fb54d7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.63']} DrugCentral uuid:5fb57a5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:5fb5a3b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.11']} DrugCentral uuid:5fb5cc98-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5fb5f6b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5fb61fc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:5fb648b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:5fb671a2-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:5fb69bb4-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:5fb6c490-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5fb6ed62-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.42']} DrugCentral uuid:5fb71648-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5fb741f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.41']} DrugCentral uuid:5fb76d00-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:5fb79da2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5fb79da2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5fb79da2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) DrugCentral uuid:5fb7db28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5fb7db28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:5fb81f5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:5fb81f5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:5fb81f5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:5fb81f5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:5fb81f5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic kainate) DrugCentral uuid:5fb879a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:5fb879a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:5fb879a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:5fb879a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) DrugCentral uuid:5fb8bed0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:5fb8e7ac-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiramate targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:5fb91254-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.818']} DrugCentral uuid:5fb93b26-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:5fb960d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:5fb98572-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) DrugCentral uuid:5fb9aa52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:5fb9cece-6b31-11ec-b3df-0242ac110002 UniProtKB:O15439 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Multidrug resistance-associated protein 4) DrugCentral uuid:5fb9f390-6b31-11ec-b3df-0242ac110002 UniProtKB:Q969P6 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan is inhibitor of Enzyme (DNA topoisomerase I, mitochondrial) DrugCentral uuid:5fba180c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.58']} DrugCentral uuid:5fba416a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:5fba6a46-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:5fba9322-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5fbabbfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fbae73c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04750 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Enzyme (DNA topoisomerase I) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5fbb1018-6b31-11ec-b3df-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:5fbb38d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WIQ1 biolink:molecularly_interacts_with DrugCentral:2707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topotecan targets Enzyme (UDP-galactopyranose mutase) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5fbb619e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:2708 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 torsemide is inhibitor of Transporter (Solute carrier family 12 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5fbb8ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toremifene targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:5fbbb3c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:2709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toremifene is modulator of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:5fbbd840-6b31-11ec-b3df-0242ac110002 UniProtKB:P62508 biolink:molecularly_interacts_with DrugCentral:2709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toremifene targets Nuclear hormone receptor (Estrogen-related receptor gamma) DrugCentral uuid:5fbbfcc6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05320 biolink:molecularly_interacts_with DrugCentral:2709 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toremifene targets Unclassified (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5fbc2656-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:5fbc5022-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:5fbc78ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:5fbca1bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:5fbccba6-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.03']} DrugCentral uuid:5fbcf482-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5fbd1d40-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2711 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramadol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:5fbd46c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2712 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trandolapril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:5fbd6fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranexamic acid is inhibitor of Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:5fbd99a0-6b31-11ec-b3df-0242ac110002 UniProtKB:O60760 biolink:molecularly_interacts_with DrugCentral:2714 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranilast targets Enzyme (Hematopoietic prostaglandin D synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.94']} DrugCentral uuid:5fbdc27c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.229']} DrugCentral uuid:5fbdec0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.225']} DrugCentral uuid:5fbe14f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:5fbe3de2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11509 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Cytochrome P450 2A6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.187']} DrugCentral uuid:5fbe66f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.48']} DrugCentral uuid:5fbe9198-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.62']} DrugCentral uuid:5fbebb32-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5fbee666-6b31-11ec-b3df-0242ac110002 UniProtKB:P20813 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Cytochrome P450 2B6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:5fbf0f60-6b31-11ec-b3df-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.88']} DrugCentral uuid:5fbf38be-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:5fbf61b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:5fbf8a8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:5fbfb406-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:5fbfdd14-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5fc0060e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NB78 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (Lysine-specific histone demethylase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5fc02ef4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:2715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tranylcypromine targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5fc05956-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:2716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 travoprost targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:5fc08494-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:2716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 travoprost is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.284']} DrugCentral uuid:5fc0ad7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.428']} DrugCentral uuid:5fc0d70a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:5fc10040-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:5fc12912-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.033']} DrugCentral uuid:5fc15202-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:5fc17ae8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:5fc1a55e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fc1ce3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:5fc1f748-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:5fc2201a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.08']} DrugCentral uuid:5fc24a18-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:5fc272ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.749']} DrugCentral uuid:5fc29bda-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.551']} DrugCentral uuid:5fc2c510-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:5fc2edf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.896']} DrugCentral uuid:5fc316dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:5fc33f9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.483']} DrugCentral uuid:5fc36916-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.975']} DrugCentral uuid:5fc391e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:5fc3bae2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5fc3e3b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.153']} DrugCentral uuid:5fc40e48-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.328']} DrugCentral uuid:5fc43756-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:5fc46046-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.081']} DrugCentral uuid:5fc48936-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.083']} DrugCentral uuid:5fc4b280-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.93']} DrugCentral uuid:5fc4db48-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:5fc50442-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:5fc52d0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5fc556b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04439 biolink:molecularly_interacts_with DrugCentral:2717 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trazodone targets Unclassified (HLA class I histocompatibility antigen, A-3 alpha chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5fc57f94-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5fc5a992-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5fc5d520-6b31-11ec-b3df-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:5fc60158-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5fc62c78-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5fc6554a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:2720 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 treprostinil is agonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:5fc67ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.642']} DrugCentral uuid:5fc6a798-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.525']} DrugCentral uuid:5fc6d092-6b31-11ec-b3df-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5fc6f950-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92781 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Enzyme (11-cis retinol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5fc722cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35398 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Nuclear receptor ROR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5fc74b9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5fc77484-6b31-11ec-b3df-0242ac110002 UniProtKB:P28702 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5fc79d9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5fc7c8da-6b31-11ec-b3df-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5fc7f22e-6b31-11ec-b3df-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5fc81af6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5fc84440-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92753 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is antagonist of Nuclear hormone receptor (Nuclear receptor ROR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.82']} DrugCentral uuid:5fc86cf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P51449 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:5fc895e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:5fc8bed4-6b31-11ec-b3df-0242ac110002 UniProtKB:P40220 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5fc8e7ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P28704 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:5fc910c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28705 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5fc9399a-6b31-11ec-b3df-0242ac110002 UniProtKB:P62965 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.4']} DrugCentral uuid:5fc96280-6b31-11ec-b3df-0242ac110002 UniProtKB:P22935 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Cytosolic other (Cellular retinoic acid-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5fc98eb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11416 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5fc9b942-6b31-11ec-b3df-0242ac110002 UniProtKB:P28700 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5fc9e232-6b31-11ec-b3df-0242ac110002 UniProtKB:P22605 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:5fca0b18-6b31-11ec-b3df-0242ac110002 UniProtKB:P18911 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Transcription factor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:5fca34b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:5fca5d8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear hormone receptor (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5fca8656-6b31-11ec-b3df-0242ac110002 UniProtKB:P49116 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear other (Nuclear receptor subfamily 2 group C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:5fcaafd2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13526 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin targets Unclassified (Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:5fcad8cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y466 biolink:molecularly_interacts_with DrugCentral:2722 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretinoin is agonist of Nuclear other (Nuclear receptor subfamily 2 group E member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:5fcb0176-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.27']} DrugCentral uuid:5fcb2a84-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:5fcb54d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:5fcb80e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:5fcba9fa-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.76']} DrugCentral uuid:5fcbda6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5fcbda6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5fcbda6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:5fcc2b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5fcc2b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5fcc2b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5fcc2b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5fcc2b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5fcc984c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5fcc984c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5fcc984c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5fcc984c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5fcc984c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5fcc984c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:5fcd058e-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5fcd058e-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5fcd058e-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:2723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tretoquinol targets GPCR (Adrenergic receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:5fcd4abc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.585']} DrugCentral uuid:5fcd76a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone targets Cytosolic other (Annexin A1) DrugCentral uuid:5fcd9c7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:2725 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone targets Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:5fcdc1ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone acetonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:5fcdeada-6b31-11ec-b3df-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:2726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone acetonide targets Cytosolic other (Annexin A1) DrugCentral uuid:5fce0f60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:2726 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone acetonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:5fce38dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:2727 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone diacetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:5fce5de4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13621 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Transporter (Solute carrier family 12 member 1) DrugCentral uuid:5fce8300-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:5fceabdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P29466 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Enzyme (Caspase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.436']} DrugCentral uuid:5fced4a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08311 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Enzyme (Cathepsin G) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5fcefeca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01782 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene targets Enzyme (Pteridine reductase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5fcf30ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5fcf30ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5fcf30ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P51170 biolink:molecularly_interacts_with DrugCentral:2728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamterene is blocker of Ion channel (Amiloride-sensitive sodium channel, ENaC) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5fcf718e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.27']} DrugCentral uuid:5fcf9c0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25105 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets GPCR (Platelet-activating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.879']} DrugCentral uuid:5fcfc4f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:5fcff56e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:5fcff56e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:5fcff56e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:5fd03f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:5fd03f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:5fd03f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:5fd08826-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:5fd08826-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:5fd08826-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.845']} DrugCentral uuid:5fd0d24a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:5fd0d24a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:5fd0d24a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.02']} DrugCentral uuid:5fd11be2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.638']} DrugCentral uuid:5fd11be2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.638']} DrugCentral uuid:5fd11be2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.638']} DrugCentral uuid:5fd16692-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:5fd16692-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:5fd16692-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd1e00e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd2eb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA-A receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fd3ac54-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.876']} DrugCentral uuid:5fd3ac54-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.876']} DrugCentral uuid:5fd3ac54-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.876']} DrugCentral uuid:5fd3f682-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.108']} DrugCentral uuid:5fd3f682-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.108']} DrugCentral uuid:5fd3f682-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.108']} DrugCentral uuid:5fd43f0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5fd43f0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5fd43f0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5fd48ab6-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:5fd48ab6-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:5fd48ab6-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:5fd4d34a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5fd4d34a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5fd4d34a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2729 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triazolam is positive allosteric modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.699']} DrugCentral uuid:5fd51454-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.04']} DrugCentral uuid:5fd53d62-6b31-11ec-b3df-0242ac110002 UniProtKB:P55017 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide is inhibitor of Transporter (Solute carrier family 12 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'A2', 'has_quantitative_value': ['7']} DrugCentral uuid:5fd56616-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:5fd58f10-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.35']} DrugCentral uuid:5fd5b832-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:5fd5e136-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.51']} DrugCentral uuid:5fd60a9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:5fd63384-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:5fd65e04-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5fd686fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:5fd6afd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:5fd6d99c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trichlormethiazide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:5fd702dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P25779 biolink:molecularly_interacts_with DrugCentral:2734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclabendazole targets Enzyme (Cruzipain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd7645c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2735 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclofos is positive modulator of Ion channel (GABA-A receptor; anion channel) DrugCentral uuid:5fd826bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2737 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tridihexethyl is antagonist of GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5fd84b92-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2737 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tridihexethyl is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:5fd87036-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:5fd89912-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:5fd8c266-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:5fd8eb60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:5fd91428-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5fd93e4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:5fd9678e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.31']} DrugCentral uuid:5fd9907e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:5fd9b96e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:5fd9e33a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.37']} DrugCentral uuid:5fda0d4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5fda3650-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.28']} DrugCentral uuid:5fda5f4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2738 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trientine targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.23']} DrugCentral uuid:5fda883a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.841']} DrugCentral uuid:5fdab184-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.185']} DrugCentral uuid:5fdada7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:5fdb0364-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.292']} DrugCentral uuid:5fdb2ca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5fdb558a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:5fdb7e7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.022']} DrugCentral uuid:5fdba760-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:5fdbd212-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:5fdbfddc-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.849']} DrugCentral uuid:5fdc276c-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.536']} DrugCentral uuid:5fdc505c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:5fdc7992-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.786']} DrugCentral uuid:5fdca2fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.251']} DrugCentral uuid:5fdccbf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5fdcf4da-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5fdd1dfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.407']} DrugCentral uuid:5fdd4700-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.377']} DrugCentral uuid:5fdd7810-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5fdd7810-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5fdd7810-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:5fddbcee-6b31-11ec-b3df-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.64']} DrugCentral uuid:5fdde5d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.27']} DrugCentral uuid:5fde0eba-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:5fde3818-6b31-11ec-b3df-0242ac110002 UniProtKB:P78527 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Kinase (DNA-dependent protein kinase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:5fde60ea-6b31-11ec-b3df-0242ac110002 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.15']} DrugCentral uuid:5fde89da-6b31-11ec-b3df-0242ac110002 UniProtKB:P06760 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (Beta-glucuronidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.11']} DrugCentral uuid:5fdeb28e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00697 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (Lysozyme C-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:5fdedbce-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5fdf04aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:5fdf2da4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BY08 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Enzyme (Emopamil-binding protein-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:5fdf5e1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:5fdf5e1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:5fdf5e1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:5fdfaaea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5fdfaaea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5fdfaaea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5fdff360-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.98']} DrugCentral uuid:5fdff360-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.98']} DrugCentral uuid:5fdff360-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.98']} DrugCentral uuid:5fe034ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:2740 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluoperazine targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:5fe05d8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.699']} DrugCentral uuid:5fe08686-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:5fe0b016-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:5fe0d8f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.456']} DrugCentral uuid:5fe101ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.456']} DrugCentral uuid:5fe12bc2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:5fe155fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluperidol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:5fe17f14-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:5fe1a7f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5fe1d0cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.398']} DrugCentral uuid:5fe1fa02-6b31-11ec-b3df-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:5fe22306-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:5fe24bec-6b31-11ec-b3df-0242ac110002 UniProtKB:P33302 biolink:molecularly_interacts_with DrugCentral:2742 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triflupromazine targets Transporter (Pleiotropic ABC efflux transporter of multiple drugs) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:5fe274be-6b31-11ec-b3df-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:2743 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluridine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5fe29e3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WKE1 biolink:molecularly_interacts_with DrugCentral:2743 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifluridine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.01']} DrugCentral uuid:5fe2c7ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.347']} DrugCentral uuid:5fe2f0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5fe31a72-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.73']} DrugCentral uuid:5fe3434e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:5fe36c20-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:5fe39510-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.99']} DrugCentral uuid:5fe3bed2-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2745 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trihexyphenidyl targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.611']} DrugCentral uuid:5fe3e7c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P26439 biolink:molecularly_interacts_with DrugCentral:2746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilostane is inhibitor of Enzyme (3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2) DrugCentral uuid:5fe40c48-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alimemazine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:5fe430f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:2749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alimemazine targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:5fe45a4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63704 biolink:molecularly_interacts_with DrugCentral:2750 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetazidine targets Enzyme (Carnitine O-palmitoyltransferase 1, muscle isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:5fe4831c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2751 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethadione is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:5fe4a7a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZZ6 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan targets Ion channel (Neuronal acetylcholine receptor subunit alpha-10) DrugCentral uuid:5fe4cc14-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) DrugCentral uuid:5fe4f1bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:5fe51a98-6b31-11ec-b3df-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:5fe54874-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:5fe54874-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetaphan is antagonist of Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) DrugCentral uuid:5fe5775e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5fe5a0a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:5fe5c97a-6b31-11ec-b3df-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:5fe5f38c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:5fe61c68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q27713 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:5fe645da-6b31-11ec-b3df-0242ac110002 UniProtKB:P13922 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.99']} DrugCentral uuid:5fe66eca-6b31-11ec-b3df-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5fe6979c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:5fe6c136-6b31-11ec-b3df-0242ac110002 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5fe6eb0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:5fe71406-6b31-11ec-b3df-0242ac110002 UniProtKB:P07807 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:5fe73cc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07382 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.921']} DrugCentral uuid:5fe765fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P22906 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:5fe78ec2-6b31-11ec-b3df-0242ac110002 UniProtKB:O30463 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:5fe7b7a8-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5fe7e0fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q27793 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:5fe80a64-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A017 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:5fe83336-6b31-11ec-b3df-0242ac110002 UniProtKB:Q27783 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:5fe85c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04174 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:5fe88516-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59487 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:5fe8aee2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q81R22 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.62']} DrugCentral uuid:5fe8d7c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q27552 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:5fe900a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00382 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:5fe92a5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8Z9J9 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.08']} DrugCentral uuid:5fe953c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q54801 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:5fe97ca0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UUP5 biolink:molecularly_interacts_with DrugCentral:2755 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimethoprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:5fe9a57c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:5fe9cec6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05932 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Folylpolyglutamate synthase, mitochondrial) DrugCentral uuid:5fe9f356-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07422 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.29']} DrugCentral uuid:5fea1c46-6b31-11ec-b3df-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:5fea4522-6b31-11ec-b3df-0242ac110002 UniProtKB:P00375 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:5fea6f02-6b31-11ec-b3df-0242ac110002 UniProtKB:Q920D2 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:5fea97d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P0ABQ4 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5feac0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P00381 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:5feae98c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07807 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:5feb12b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22906 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:5feb3b8a-6b31-11ec-b3df-0242ac110002 UniProtKB:O30463 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:5feb647a-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:5feb8d42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q27793 biolink:molecularly_interacts_with DrugCentral:2757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimetrexate targets Enzyme (Bifunctional dihydrofolate reductase-thymidylate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.18']} DrugCentral uuid:5febb704-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.827']} DrugCentral uuid:5febdffe-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:5fec08ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.854']} DrugCentral uuid:5fec31de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.423']} DrugCentral uuid:5fec5df8-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trimipramine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.56']} DrugCentral uuid:5fec8724-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:2759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trioxsalen targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.133']} DrugCentral uuid:5fecb140-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trioxsalen targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.909']} DrugCentral uuid:5fecda8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2759 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trioxsalen targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:5fed03b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triparanol targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:5fed2d96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15125 biolink:molecularly_interacts_with DrugCentral:2761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triparanol targets Enzyme (3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:5fed5686-6b31-11ec-b3df-0242ac110002 UniProtKB:P32352 biolink:molecularly_interacts_with DrugCentral:2761 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triparanol targets Enzyme (C-8 sterol isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:5fed80a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2762 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tripelennamine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:5feda988-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triprolidine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:5fedd264-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2763 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triprolidine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.9']} DrugCentral uuid:5fedfb54-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.208']} DrugCentral uuid:5fee257a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.078']} DrugCentral uuid:5fee4e6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.531']} DrugCentral uuid:5fee7746-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.013']} DrugCentral uuid:5feea022-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:5feec930-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:5feef202-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:5fef1ae8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:5fef4400-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Aldose reductase) DrugCentral uuid:5fef6944-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:5fef91f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:5fefbac0-6b31-11ec-b3df-0242ac110002 UniProtKB:P54840 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Glycogen [starch] synthase, liver) DrugCentral uuid:5fefdf46-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.528']} DrugCentral uuid:5ff00b74-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.691']} DrugCentral uuid:5ff03540-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.907']} DrugCentral uuid:5ff05e08-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:5ff0875c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5ff0b042-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R0V5 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Indoleamine 2,3-dioxygenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:5ff0d91e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19224 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (UDP-glucuronosyltransferase 1-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5ff101f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28776 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:5ff12b58-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:5ff1552e-6b31-11ec-b3df-0242ac110002 UniProtKB:P39654 biolink:molecularly_interacts_with DrugCentral:2767 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troglitazone targets Enzyme (Polyunsaturated fatty acid lipoxygenase ALOX15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:5ff17e0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2769 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 troleandomycin is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:5ff1a704-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.167']} DrugCentral uuid:5ff1d21a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:5ff1fbdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.523']} DrugCentral uuid:5ff224ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:5ff24d9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:5ff276de-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5ff29fce-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2774 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropicamide targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:5ff2c8aa-6b31-11ec-b3df-0242ac110002 UniProtKB:O70528 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:5ff2f1a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.587']} DrugCentral uuid:5ff31b34-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:5ff3441a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.606']} DrugCentral uuid:5ff36d96-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5ff39910-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5ff3c520-6b31-11ec-b3df-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:5ff3f004-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:5ff418f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:5ff4422a-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of Ion channel (Glycine receptor subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:5ff46b24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:5ff493ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5ff4bcdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P49582 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:5ff4e66c-6b31-11ec-b3df-0242ac110002 UniProtKB:O70212 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:5ff51326-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5ff51326-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:5ff54cf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:5ff54cf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.26']} DrugCentral uuid:5ff59166-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5ff59166-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5ff59166-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5ff59166-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:5ff5e4f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5ff5e4f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JHJ5 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:5ff61a5a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:5ff64340-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron targets Ion channel (Neuronal acetylcholine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:5ff66c58-6b31-11ec-b3df-0242ac110002 UniProtKB:P97288 biolink:molecularly_interacts_with DrugCentral:2775 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tropisetron is antagonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5ff6952a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trospium targets GPCR (Muscarinic acetylcholine receptor M1) DrugCentral uuid:5ff6ba6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trospium is antagonist of GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:5ff6defe-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trospium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:5ff7038e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2776 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trospium targets GPCR (Muscarinic acetylcholine receptor M5) DrugCentral uuid:5ff72828-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.306']} DrugCentral uuid:5ff7538e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.395']} DrugCentral uuid:5ff781ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:5ff781ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:5ff7b48c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5ff7b48c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:2777 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trovafloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:5ff7e3ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:2780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tryptophan is allosteric modulator of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:5ff80cca-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tryptophan targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:5ff835a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6DWJ6 biolink:molecularly_interacts_with DrugCentral:2780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tryptophan is agonist of GPCR (Probable G-protein coupled receptor 139) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5ff85e64-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:2780 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tryptophan targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:5ff887b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.013']} DrugCentral uuid:5ff8b080-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:5ff8da6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:5ff9033c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UGI6 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5ff92e2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2S1 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5ff956f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:5ff98104-6b31-11ec-b3df-0242ac110002 UniProtKB:P70605 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:5ff9aa6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q401N2 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Zinc-activated ligand-gated ion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:5ff9d398-6b31-11ec-b3df-0242ac110002 UniProtKB:P23979 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5ff9fca6-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:5ffa2578-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:5ffa4efe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:5ffa77e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:5ffaa0ac-6b31-11ec-b3df-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:5ffacd66-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:5ffacd66-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:5ffb0dee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:5ffb0dee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:5ffb0dee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:5ffb52d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:5ffb52d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.38']} DrugCentral uuid:5ffb8bf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:5ffb8bf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.579']} DrugCentral uuid:5ffbc4b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5ffbc4b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:5ffbfd6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.066']} DrugCentral uuid:5ffbfd6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.066']} DrugCentral uuid:5ffc4056-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5ffc4056-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5ffc4056-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5ffc4056-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:5ffc90ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5ffc90ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is antagonist of Ion channel (Serotonin 3 receptor (5HT3)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:5ffcc76a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92952 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffd28b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:5ffe077e-6b31-11ec-b3df-0242ac110002 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:2781 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tubocurarine is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:5ffe303c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:2782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tulobuterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:5ffe592c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2782 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tulobuterol is agonist of GPCR (Beta-2 adrenergic receptor) DrugCentral uuid:5ffe7dc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.59']} DrugCentral uuid:5ffea904-6b31-11ec-b3df-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['2.7']} DrugCentral uuid:5ffed4d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:5ffeffbc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:5fff2898-6b31-11ec-b3df-0242ac110002 UniProtKB:H9TVJ1 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (TyR1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:5fff82fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine targets GPCR (Serotonin (5-HT) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:60004746-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:2784 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyramine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:600071b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:2786 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tyrosine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:60009ae8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:6000c3a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P15144 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:6000ed5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28838 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:60011734-6b31-11ec-b3df-0242ac110002 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:60014010-6b31-11ec-b3df-0242ac110002 UniProtKB:P15145 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:600168e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O96935 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (M1 family aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.72']} DrugCentral uuid:600191aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VCT3 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:6001bb12-6b31-11ec-b3df-0242ac110002 UniProtKB:P97629 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Leucyl-cystinyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:6001e3ee-6b31-11ec-b3df-0242ac110002 UniProtKB:O09175 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:60020cb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00727 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:60023588-6b31-11ec-b3df-0242ac110002 UniProtKB:P97449 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:60026076-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01693 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Bacterial leucyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:60028948-6b31-11ec-b3df-0242ac110002 UniProtKB:P28839 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:6002b206-6b31-11ec-b3df-0242ac110002 UniProtKB:P15684 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Aminopeptidase N) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:6002db46-6b31-11ec-b3df-0242ac110002 UniProtKB:P55786 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Puromycin-sensitive aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:60030422-6b31-11ec-b3df-0242ac110002 UniProtKB:P28839 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:60032d26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZ08 biolink:molecularly_interacts_with DrugCentral:2787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubenimex targets Enzyme (Endoplasmic reticulum aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:600356fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urapidil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.456']} DrugCentral uuid:60038096-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urapidil is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.85']} DrugCentral uuid:6003a972-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urapidil is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:6003d26c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urapidil is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:6003fb34-6b31-11ec-b3df-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol targets Enzyme (Aldo-keto reductase family 1 member C2) DrugCentral uuid:600421e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol is agonist of Nuclear hormone receptor (Bile acid receptor) DrugCentral uuid:600446ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:60046f60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:6004983c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZ45 biolink:molecularly_interacts_with DrugCentral:2797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ursodiol targets Unclassified (CDGSH iron-sulfur domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:6004c17c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2798 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valaciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:6004e602-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:60050fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.57']} DrugCentral uuid:60053882-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.537']} DrugCentral uuid:600561a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:60058a76-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.37']} DrugCentral uuid:6005b33e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.27']} DrugCentral uuid:6005dc10-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.87']} DrugCentral uuid:600606fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:60062fe4-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:600658de-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.04']} DrugCentral uuid:60068264-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:6006ab7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:6006d4f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:6006fdc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.24']} DrugCentral uuid:60072700-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:60074fc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00403 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Cytochrome c oxidase subunit 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:600778a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:6007a176-6b31-11ec-b3df-0242ac110002 UniProtKB:Q95323 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:6007cb2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P40881 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:6007f40a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q50565 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:60081cf0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:600845b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.18']} DrugCentral uuid:60086f5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:60089838-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:6008c11e-6b31-11ec-b3df-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:6008e9fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:6009143e-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60093d1a-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:60096614-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:60098ff4-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.29']} DrugCentral uuid:6009ba60-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:6009e332-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:600a0c36-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:600a36f2-6b31-11ec-b3df-0242ac110002 UniProtKB:O78749 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Cytochrome c oxidase subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:600a5f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:600a8878-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:600ab154-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valdecoxib targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.28']} DrugCentral uuid:600adabc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:600b038e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.56']} DrugCentral uuid:600b2c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:600b55c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.25']} DrugCentral uuid:600b811a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:600ba9f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:600bd2c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:2800 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valethamate targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:600bfc26-6b31-11ec-b3df-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valganciclovir is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:600c2160-6b31-11ec-b3df-0242ac110002 UniProtKB:P51649 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid is inhibitor of Enzyme (Succinate-semialdehyde dehydrogenase, mitochondrial) DrugCentral uuid:600c45dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:600c6ea4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:600c976c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14550 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:600cc08e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:600ce988-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:600d1246-6b31-11ec-b3df-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:600d3ce4-6b31-11ec-b3df-0242ac110002 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:600d65b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35504 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (UDP-glucuronosyltransferase 1-5) DrugCentral uuid:600d8a3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5RJP0 biolink:molecularly_interacts_with DrugCentral:2803 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valproic acid targets Enzyme (Aldose reductase-related protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:600db304-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:2805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valrubicin is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:600dd85c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.33']} DrugCentral uuid:600e012e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:600e2a00-6b31-11ec-b3df-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:600e569c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:600e569c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:2806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valsartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:600e8bd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vancomycin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:600eb4ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06241 biolink:molecularly_interacts_with DrugCentral:2807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vancomycin targets Enzyme (D-alanyl-D-alanine dipeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:600edd88-6b31-11ec-b3df-0242ac110002 UniProtKB:P17443 biolink:molecularly_interacts_with DrugCentral:2807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vancomycin targets Enzyme (UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:600f065a-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:600f2ffe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:600f5ca4-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:600f5ca4-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.66']} DrugCentral uuid:600f9548-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:600f9548-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:600fceaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:600fceaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.07']} DrugCentral uuid:60100758-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:60100758-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:60104010-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:60104010-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:60107a80-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:60107a80-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline is agonist of Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:6010b45a-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:6010b45a-6b31-11ec-b3df-0242ac110002 UniProtKB:P32297 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.066']} DrugCentral uuid:6010ee84-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:6010ee84-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:60112eee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:60112eee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:60112eee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:60112eee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:60118056-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:60118056-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:6011c0c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:6011c0c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:6011c0c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:6011c0c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:2808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 varenicline targets Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:60120d96-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:601236b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.465']} DrugCentral uuid:60125f8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCR9 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:60128866-6b31-11ec-b3df-0242ac110002 UniProtKB:P54750 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.041']} DrugCentral uuid:6012b1ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:6012de4c-6b31-11ec-b3df-0242ac110002 UniProtKB:O00408 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (cGMP-dependent 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:601307a0-6b31-11ec-b3df-0242ac110002 UniProtKB:O76083 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:60133428-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:60133428-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:60137604-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:60137604-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:60137604-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:60137604-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:6013c690-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:6013c690-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vardenafil targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:6013fbf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin is agonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.59']} DrugCentral uuid:60142536-6b31-11ec-b3df-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin is agonist of GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:60144e30-6b31-11ec-b3df-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin is agonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:60147720-6b31-11ec-b3df-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.78']} DrugCentral uuid:6014a1f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P32307 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:6014cab8-6b31-11ec-b3df-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.93']} DrugCentral uuid:6014f394-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.35']} DrugCentral uuid:60151c52-6b31-11ec-b3df-0242ac110002 UniProtKB:P48044 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:601545d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:60156ea0-6b31-11ec-b3df-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:60159b96-6b31-11ec-b3df-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:60159b96-6b31-11ec-b3df-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:2810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vasopressin targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:6015d228-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:6015fb04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:601623e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:60165072-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:60165072-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta4) DrugCentral uuid:601688d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:601688d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:601688d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium is antagonist of Ion channel (Acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:6016ce58-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:6016ce58-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) DrugCentral uuid:601701de-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:601701de-6b31-11ec-b3df-0242ac110002 UniProtKB:P43681 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) DrugCentral uuid:60173c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:60173c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:60173c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:60173c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vecuronium targets Ion channel (Acetylcholine receptor; alpha1/beta1/delta/gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:6017892e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.051']} DrugCentral uuid:6017b2a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.975']} DrugCentral uuid:6017db7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.652']} DrugCentral uuid:60180462-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.698']} DrugCentral uuid:60182d34-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.554']} DrugCentral uuid:601858e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:601881d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:6018aaac-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:6018d432-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:6018fd90-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:60192680-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venlafaxine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:60194f3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Sodium channel protein type 5 subunit alpha) DrugCentral uuid:6019743c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.664']} DrugCentral uuid:60199d04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:6019c5d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:6019eec6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.52']} DrugCentral uuid:601a19aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.896']} DrugCentral uuid:601a42ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.763']} DrugCentral uuid:601a6cb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:601a9600-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.979']} DrugCentral uuid:601abf90-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:601ae876-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.201']} DrugCentral uuid:601b1152-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.594']} DrugCentral uuid:601b3a06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:601b6350-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.072']} DrugCentral uuid:601b8d9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:601bb68e-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.88']} DrugCentral uuid:601be078-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.43']} DrugCentral uuid:601c0bac-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Enzyme (Carbonic anhydrase 1) DrugCentral uuid:601c303c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48051 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (G protein-activated inward rectifier potassium channel 2) DrugCentral uuid:601c54c2-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.485']} DrugCentral uuid:601c7e7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13698 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) DrugCentral uuid:601ca314-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16322 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:601ccbfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P22001 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily A member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:601cf4cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96PR1 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:601d1e0c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:601d46d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.348']} DrugCentral uuid:601d6f92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RP8 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:601d9864-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:601dc30c-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:601debca-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:601e149c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:601e3d64-6b31-11ec-b3df-0242ac110002 UniProtKB:P15381 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:601e67d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:601e9098-6b31-11ec-b3df-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:601eb960-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1S) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:601ee228-6b31-11ec-b3df-0242ac110002 UniProtKB:P06199 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:601f0b54-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.071']} DrugCentral uuid:601f3c78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:601f3c78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:601f3c78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:601f858e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:601f858e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:601f858e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02485 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.43']} DrugCentral uuid:601fc710-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.73']} DrugCentral uuid:601ff00a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N623 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil targets Transporter (Chloroquine resistance transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:602018d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22462 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:6020423a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULQ1 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Two pore calcium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:60206b02-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NHX9 biolink:molecularly_interacts_with DrugCentral:2815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 verapamil is blocker of Ion channel (Two pore calcium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:602093e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:6020bd28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:6020e5dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13370 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (cGMP-inhibited 3',5'-cyclic phosphodiesterase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:60211282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:60211282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:6021475c-6b31-11ec-b3df-0242ac110002 UniProtKB:P55072 biolink:molecularly_interacts_with DrugCentral:2817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vesnarinone targets Enzyme (Transitional endoplasmic reticulum ATPase) DrugCentral uuid:60216dfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P04293 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine is inhibitor of Enzyme (DNA polymerase catalytic subunit) DrugCentral uuid:6021932e-6b31-11ec-b3df-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:6021b7a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P09884 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (DNA polymerase alpha catalytic subunit) DrugCentral uuid:6021de10-6b31-11ec-b3df-0242ac110002 UniProtKB:P23921 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Ribonucleoside-diphosphate reductase large subunit) DrugCentral uuid:60220318-6b31-11ec-b3df-0242ac110002 UniProtKB:P31350 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Ribonucleoside-diphosphate reductase subunit M2) DrugCentral uuid:60222794-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16854 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Kinase (Deoxyguanosine kinase, mitochondrial) DrugCentral uuid:60224c10-6b31-11ec-b3df-0242ac110002 UniProtKB:P60891 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Kinase (Ribose-phosphate pyrophosphokinase 1) DrugCentral uuid:60227096-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:6022b9fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04400 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Adenylate cyclase type V) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:6022f02a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50247 biolink:molecularly_interacts_with DrugCentral:2818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vidarabine targets Enzyme (Adenosylhomocysteinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:60231938-6b31-11ec-b3df-0242ac110002 UniProtKB:P80404 biolink:molecularly_interacts_with DrugCentral:2819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vigabatrin is inhibitor of Enzyme (4-aminobutyrate aminotransferase, mitochondrial) DrugCentral uuid:60233f94-6b31-11ec-b3df-0242ac110002 UniProtKB:P50554 biolink:molecularly_interacts_with DrugCentral:2819 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vigabatrin targets Enzyme (Gamma-amino-N-butyrate transaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:60236870-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.76']} DrugCentral uuid:60239156-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.81']} DrugCentral uuid:6023ba3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.78']} DrugCentral uuid:6023e3c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:60240cd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTR4 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:602435c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viloxazine is antagonist of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:60245eb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:6024880e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:6024ac8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:6024d106-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:6024f58c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.728']} DrugCentral uuid:60251fee-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.298']} DrugCentral uuid:602548a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:60259118-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:60259118-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:60259118-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:60259118-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:60259118-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:60259118-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:60259118-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:60259118-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:60259118-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinblastine is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:60261b74-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:602644be-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.2']} DrugCentral uuid:60266da4-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:60269680-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinburnine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.6']} DrugCentral uuid:6026bf3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:6026e568-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:60270c96-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:602733d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5T3U5 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Transporter (Multidrug resistance-associated protein 7) DrugCentral uuid:60276006-6b31-11ec-b3df-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:60276006-6b31-11ec-b3df-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:60276006-6b31-11ec-b3df-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:6027c12c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6027c12c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6027c12c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6027c12c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6027c12c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6027c12c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6027c12c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6027c12c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6027c12c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2825 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincristine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:602838c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vindesine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['4.607']} DrugCentral uuid:602861ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60288a9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.271']} DrugCentral uuid:6028d4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6028d4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6028d4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6028d4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6028d4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6028d4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6028d4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6028d4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6028d4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:2827 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinorelbine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:60294e70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:6029774c-6b31-11ec-b3df-0242ac110002 UniProtKB:P54750 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine targets Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:6029a01e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14123 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine is inhibitor of Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:6029ccce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:6029ccce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:2828 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinpocetine targets Enzyme (Phosphodiesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:602a0266-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92781 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (11-cis retinol dehydrogenase) DrugCentral uuid:602a26d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NR8 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (Retinol dehydrogenase 12) DrugCentral uuid:602a4b36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NBN7 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (Retinol dehydrogenase 13) DrugCentral uuid:602a6fb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P10745 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Surface antigen (Retinol-binding protein 3) DrugCentral uuid:602a9640-6b31-11ec-b3df-0242ac110002 UniProtKB:P82980 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Cytosolic other (Retinol-binding protein 5) DrugCentral uuid:602ababc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96R05 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Cytosolic other (Retinoid-binding protein 7) DrugCentral uuid:602adf42-6b31-11ec-b3df-0242ac110002 UniProtKB:P02753 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Secreted (Retinol-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:602b0814-6b31-11ec-b3df-0242ac110002 UniProtKB:P50120 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Cytosolic other (Retinol-binding protein 2) DrugCentral uuid:602b2cea-6b31-11ec-b3df-0242ac110002 UniProtKB:O94788 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (Retinal dehydrogenase 2) DrugCentral uuid:602b515c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00352 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Enzyme (Retinal dehydrogenase 1) DrugCentral uuid:602b75ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P12271 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Transporter (Retinaldehyde-binding protein 1) DrugCentral uuid:602b9a40-6b31-11ec-b3df-0242ac110002 UniProtKB:P02754 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Unclassified (Beta-lactoglobulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:602bc358-6b31-11ec-b3df-0242ac110002 UniProtKB:P09455 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol targets Cytosolic other (Retinol-binding protein 1) DrugCentral uuid:602be7de-6b31-11ec-b3df-0242ac110002 UniProtKB:P49116 biolink:molecularly_interacts_with DrugCentral:2831 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retinol is agonist of Nuclear other (Nuclear receptor subfamily 2 group C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.71']} DrugCentral uuid:602c1092-6b31-11ec-b3df-0242ac110002 UniProtKB:O60779 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Transporter (Thiamine transporter 1) DrugCentral uuid:602c359a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29401 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Enzyme (Transketolase) DrugCentral uuid:602c5b1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3S4 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Kinase (Thiamin pyrophosphokinase 1) DrugCentral uuid:602c80b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BU02 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Enzyme (Thiamine-triphosphatase) DrugCentral uuid:602ca61a-6b31-11ec-b3df-0242ac110002 UniProtKB:P51854 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Enzyme (Transketolase-like protein 1) DrugCentral uuid:602cca8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07900 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Cytosolic other (Heat shock protein HSP 90-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:602cf3ea-6b31-11ec-b3df-0242ac110002 UniProtKB:A2RI47 biolink:molecularly_interacts_with DrugCentral:2832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiamine targets Transporter (Thiamine transporter ThiT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.91']} DrugCentral uuid:602d1cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30043 biolink:molecularly_interacts_with DrugCentral:2834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riboflavin targets Enzyme (Flavin reductase (NADPH)) DrugCentral uuid:602d4142-6b31-11ec-b3df-0242ac110002 UniProtKB:Q969G6 biolink:molecularly_interacts_with DrugCentral:2834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riboflavin targets Kinase (Riboflavin kinase) DrugCentral uuid:602d65c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P02752 biolink:molecularly_interacts_with DrugCentral:2834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riboflavin targets Unclassified (Riboflavin-binding protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:602d8ed6-6b31-11ec-b3df-0242ac110002 UniProtKB:P49019 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid is agonist of GPCR (Hydroxycarboxylic acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:602db780-6b31-11ec-b3df-0242ac110002 UniProtKB:P40261 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets Enzyme (Nicotinamide N-methyltransferase) DrugCentral uuid:602ddbf2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15274 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets Enzyme (Nicotinate-nucleotide pyrophosphorylase [carboxylating]) DrugCentral uuid:602e006e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets Enzyme (Nicotinamide phosphoribosyltransferase) DrugCentral uuid:602e24f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q80Z39 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:602e4efc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EP66 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:602e77c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.88']} DrugCentral uuid:602ea0b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:2835 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nicotinic acid is agonist of GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:602ec9f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P34896 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Serine hydroxymethyltransferase, cytosolic) DrugCentral uuid:602eee7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NVS9 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Pyridoxine-5'-phosphate oxidase) DrugCentral uuid:602f12f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD0 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Pyridoxal phosphate phosphatase) DrugCentral uuid:602f3768-6b31-11ec-b3df-0242ac110002 UniProtKB:O00764 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Kinase (Pyridoxal kinase) DrugCentral uuid:602f5c02-6b31-11ec-b3df-0242ac110002 UniProtKB:P35520 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Cystathionine beta-synthase) DrugCentral uuid:602f80ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y617 biolink:molecularly_interacts_with DrugCentral:2836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxine targets Enzyme (Phosphoserine aminotransferase) DrugCentral uuid:602fa540-6b31-11ec-b3df-0242ac110002 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:2838 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergocalciferol targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) DrugCentral uuid:602fc9c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2838 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergocalciferol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:602fee42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6VVX0 biolink:molecularly_interacts_with DrugCentral:2838 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ergocalciferol targets Enzyme (Vitamin D 25-hydroxylase) DrugCentral uuid:60301552-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:60303f00-6b31-11ec-b3df-0242ac110002 UniProtKB:O15528 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol targets Enzyme (25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial) DrugCentral uuid:6030639a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.68']} DrugCentral uuid:60308c44-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6VVX0 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol targets Enzyme (Vitamin D 25-hydroxylase) DrugCentral uuid:6030b11a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02318 biolink:molecularly_interacts_with DrugCentral:2840 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colecalciferol targets Enzyme (Sterol 26-hydroxylase, mitochondrial) DrugCentral uuid:6030d58c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:2841 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydrotachysterol targets Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:6030fa1c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose targets Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:603123d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23739 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:60314d0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6P7A9 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:603175d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35574 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.15']} DrugCentral uuid:60319eb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:2845 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voglibose is inhibitor of Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:6031c776-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:6031f3e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['8.73']} DrugCentral uuid:60321e60-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:60324732-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:60327040-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['5.844']} DrugCentral uuid:60329944-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:6032c2ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:6032ecbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P00189 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cytochrome P450 11A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:603315ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P00189 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cholesterol side-chain cleavage enzyme, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:60333eda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6A2 biolink:molecularly_interacts_with DrugCentral:2846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voriconazole targets Enzyme (Cholesterol 24-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:603367b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['3.98']} DrugCentral uuid:6033907e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.867']} DrugCentral uuid:6033bbd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BQB6 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin is inhibitor of Enzyme (Vitamin K epoxide reductase complex subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:6033e4ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16549 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin targets Enzyme (Proprotein convertase subtilisin/kexin type 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:60340d7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N0U8 biolink:molecularly_interacts_with DrugCentral:2847 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 warfarin targets Enzyme (Vitamin K epoxide reductase complex subunit 1-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.284']} DrugCentral uuid:60343664-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xamoterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.75']} DrugCentral uuid:60345fb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xamoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:60348894-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:2848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xamoterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:6034b170-6b31-11ec-b3df-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:6034da4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:60350378-6b31-11ec-b3df-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:60352d3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:60355616-6b31-11ec-b3df-0242ac110002 UniProtKB:P08709 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Coagulation factor VII) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:60358028-6b31-11ec-b3df-0242ac110002 UniProtKB:P04070 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Vitamin K-dependent protein C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:6035a8f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:6035d1d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P03951 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Coagulation factor XI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:6035fa94-6b31-11ec-b3df-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:603623f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2852 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ximelagatran is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.432']} DrugCentral uuid:60364cd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.873']} DrugCentral uuid:603675aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.114']} DrugCentral uuid:60369e9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.646']} DrugCentral uuid:6036c7da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y271 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.5']} DrugCentral uuid:6036f0ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P47712 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Cytosolic phospholipase A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:60371974-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:6037425a-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.61']} DrugCentral uuid:60376e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.419']} DrugCentral uuid:603796f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.359']} DrugCentral uuid:6037bfdc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast is antagonist of GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:6037e8ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.452']} DrugCentral uuid:603811d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15722 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets GPCR (Leukotriene B4 receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.147']} DrugCentral uuid:60383ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:6038643c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.269']} DrugCentral uuid:60388d68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2NNR5 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets GPCR (Cysteinyl leukotriene receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:6038b63a-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:6038def8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:603907de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:6039334e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:60395c20-6b31-11ec-b3df-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:60398510-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:2855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zafirlukast targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:6039adc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P27707 biolink:molecularly_interacts_with DrugCentral:2856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zalcitabine targets Kinase (Deoxycytidine kinase) DrugCentral uuid:6039d3f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2856 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zalcitabine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:603a0490-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.789']} DrugCentral uuid:603a0490-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.789']} DrugCentral uuid:603a0490-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.789']} DrugCentral uuid:603a4cde-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:603a4cde-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:603a4cde-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zaleplon is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:603a8de8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16207 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:603ab6ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P03468 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:603adfaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P03474 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:603b09b2-6b31-11ec-b3df-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:603b3270-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75VQ4 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:603b5b38-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6Q793 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:603b840a-6b31-11ec-b3df-0242ac110002 UniProtKB:A5Z252 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:603bad5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2LFS1 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:603bd644-6b31-11ec-b3df-0242ac110002 UniProtKB:C4LRQ6 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:603bff3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q20MD3 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:603c2810-6b31-11ec-b3df-0242ac110002 UniProtKB:P03470 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:603c5150-6b31-11ec-b3df-0242ac110002 UniProtKB:Q194T1 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:603c7a18-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ49 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Sialidase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:603ca2e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3R4 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Sialidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.77']} DrugCentral uuid:603cccca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07599 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:603cf6d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3S340 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:603d2044-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WWR8 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Sialidase-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.58']} DrugCentral uuid:603d4966-6b31-11ec-b3df-0242ac110002 UniProtKB:D5F1R0 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:603d7364-6b31-11ec-b3df-0242ac110002 UniProtKB:P03471 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.76']} DrugCentral uuid:603d9c90-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XV28 biolink:molecularly_interacts_with DrugCentral:2859 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanamivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:603dc53a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:603dee0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:603e1738-6b31-11ec-b3df-0242ac110002 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:603e4000-6b31-11ec-b3df-0242ac110002 UniProtKB:P23919 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:603e68dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:603e91cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:603ebbd4-6b31-11ec-b3df-0242ac110002 UniProtKB:P03362 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Polyprotein (Gag-Pro-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:603ee488-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72549 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:603f0de6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:603f36cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WKE1 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.55']} DrugCentral uuid:603f6016-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9PPP5 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:603f88e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:2861 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zidovudine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:603fb1ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton is inhibitor of Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:603fda96-6b31-11ec-b3df-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:604003c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NS75 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets GPCR (Cysteinyl leukotriene receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:60402d98-6b31-11ec-b3df-0242ac110002 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.071']} DrugCentral uuid:6040566a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15722 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets GPCR (Leukotriene B4 receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:604080d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P20292 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Cytosolic other (Arachidonate 5-lipoxygenase-activating protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:6040aade-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:6040d39c-6b31-11ec-b3df-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:6040fd5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P48999 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:604126a8-6b31-11ec-b3df-0242ac110002 UniProtKB:O14684 biolink:molecularly_interacts_with DrugCentral:2862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zileuton targets Enzyme (Prostaglandin E synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:60414f7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zimeldine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.727']} DrugCentral uuid:6041784c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zimeldine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.818']} DrugCentral uuid:6041a114-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zimeldine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.027']} DrugCentral uuid:6041ca4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.59']} DrugCentral uuid:6041f326-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:60421c02-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.02']} DrugCentral uuid:604244de-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:604271a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:60429dc6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:6042c9d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:6042f32a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:60431d46-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:6043462c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:60436f08-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.565']} DrugCentral uuid:6043985c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:6043c12e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:6043ea14-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:60441304-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:60443e74-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:60446750-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.14']} DrugCentral uuid:6044904a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.818']} DrugCentral uuid:6044b926-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:6044e2b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.456']} DrugCentral uuid:60450c78-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:60453554-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.523']} DrugCentral uuid:60455ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:6045877a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:6045b060-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.796']} DrugCentral uuid:6045d950-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:60460394-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:60462fae-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.114']} DrugCentral uuid:604658f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:60467d74-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:6046a70e-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:6046cfcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.046']} DrugCentral uuid:6046f8b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.536']} DrugCentral uuid:604722ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:60474bfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:604774d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31389 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:60479de4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:6047c6c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:6047f320-6b31-11ec-b3df-0242ac110002 UniProtKB:P31390 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:60481c42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63380 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Transporter (Transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.32']} DrugCentral uuid:60484cc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:60484cc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:60484cc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:60488ea2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07305 biolink:molecularly_interacts_with DrugCentral:2865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziprasidone targets Nuclear other (Histone H1.0) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:6048b788-6b31-11ec-b3df-0242ac110002 UniProtKB:P12822 biolink:molecularly_interacts_with DrugCentral:2866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zofenopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:6048e064-6b31-11ec-b3df-0242ac110002 UniProtKB:P47820 biolink:molecularly_interacts_with DrugCentral:2866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zofenopril targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:60490a9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:2866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zofenopril is inhibitor of Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:6049337a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:60495c56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:60498532-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:6049afd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:6049dba4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:604a048a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:604a2d7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50281 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Matrix metalloproteinase-14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:604a57a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:604a8072-6b31-11ec-b3df-0242ac110002 UniProtKB:P22894 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Neutrophil collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:604aa944-6b31-11ec-b3df-0242ac110002 UniProtKB:O95749 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:604ad234-6b31-11ec-b3df-0242ac110002 UniProtKB:P22939 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:604afb60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0GKD7 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:604b245a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12051 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:604b4d40-6b31-11ec-b3df-0242ac110002 UniProtKB:P05369 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid is inhibitor of Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:604b76a8-6b31-11ec-b3df-0242ac110002 UniProtKB:O00481 biolink:molecularly_interacts_with DrugCentral:2868 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zoledronic acid targets Unclassified (Butyrophilin subfamily 3 member A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:604ba0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:604bc9aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:604bf286-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:604c1bf8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.45']} DrugCentral uuid:604c44c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:604c6da6-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.4']} DrugCentral uuid:604c966e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.52']} DrugCentral uuid:604cc77e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:604cc77e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:604cc77e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:2869 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolmitriptan targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:604d0982-6b31-11ec-b3df-0242ac110002 UniProtKB:P14867 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:604d3268-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:604d5c3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:604d8664-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Km', 'has_quantitative_value': ['3.703']} DrugCentral uuid:604daf36-6b31-11ec-b3df-0242ac110002 UniProtKB:P16257 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Membrane receptor (Translocator protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:604dd812-6b31-11ec-b3df-0242ac110002 UniProtKB:P62813 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:604e018e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23576 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.12']} DrugCentral uuid:604e2a7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19969 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (Gamma-aminobutyric acid receptor subunit alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:604e5b02-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:604e5b02-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:604e5b02-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.703']} DrugCentral uuid:604ea404-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:604ea404-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:604ea404-6b31-11ec-b3df-0242ac110002 UniProtKB:P47869 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-2/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.807']} DrugCentral uuid:604eeca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:604eeca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:604eeca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34903 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-3/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.417']} DrugCentral uuid:604f3766-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.574']} DrugCentral uuid:604f3766-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.574']} DrugCentral uuid:604f3766-6b31-11ec-b3df-0242ac110002 UniProtKB:P28472 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.574']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:604fb25e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:6050976e-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:6050976e-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:6050976e-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.42']} DrugCentral uuid:6050dfd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:6050dfd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:6050dfd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-6/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:605129f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:605129f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:605129f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:6051726a-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:6051726a-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:6051726a-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.81']} DrugCentral uuid:6051bdd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:6051bdd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:6051bdd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem is positive allosteric modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.164']} DrugCentral uuid:6051fe92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03530 biolink:molecularly_interacts_with DrugCentral:2870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zolpidem targets Enzyme (CAAX prenyl protease 2) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:6052273c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:2871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zomepirac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:605250ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:2871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zomepirac targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.367']} DrugCentral uuid:60527d5e-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zomepirac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:60527d5e-6b31-11ec-b3df-0242ac110002 UniProtKB:O62698 biolink:molecularly_interacts_with DrugCentral:2871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zomepirac targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:6052b242-6b31-11ec-b3df-0242ac110002 UniProtKB:P35498 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide is blocker of Ion channel (Sodium channel protein type 1 subunit alpha) DrugCentral uuid:6052d862-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.99']} DrugCentral uuid:60530350-6b31-11ec-b3df-0242ac110002 UniProtKB:O43497 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1G) DrugCentral uuid:605327b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.252']} DrugCentral uuid:605350a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:605379de-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:6053a2b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.301']} DrugCentral uuid:6053cbaa-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide is inhibitor of Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:6053f49a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:60541e20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:60544710-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:60546fe2-6b31-11ec-b3df-0242ac110002 UniProtKB:O24855 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:605498c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:6054c262-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.28']} DrugCentral uuid:6054eb52-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:60551438-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:60553d8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:60556758-6b31-11ec-b3df-0242ac110002 UniProtKB:P53615 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:6055902a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:6055b924-6b31-11ec-b3df-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:6055e2b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.94']} DrugCentral uuid:60560b90-6b31-11ec-b3df-0242ac110002 UniProtKB:B5SU02 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Alpha carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.59']} DrugCentral uuid:6056346c-6b31-11ec-b3df-0242ac110002 UniProtKB:C0IX24 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.19']} DrugCentral uuid:60565d52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.01']} DrugCentral uuid:605687fa-6b31-11ec-b3df-0242ac110002 UniProtKB:A6YCJ1 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Astrosclerin-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.78']} DrugCentral uuid:6056b0e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.54']} DrugCentral uuid:6056d9bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U9J1 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Unclassified (Delta carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:605702b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ9 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:60573088-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:60573088-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase V) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.69']} DrugCentral uuid:6057658a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3SZX4 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:60578e5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6NSN2 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Amine oxidase [flavin-containing]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.51']} DrugCentral uuid:6057b97c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TU56 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.58']} DrugCentral uuid:6057e276-6b31-11ec-b3df-0242ac110002 UniProtKB:Q31FD6 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Unclassified (Carbonic anhydrase, alpha family) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:60580b48-6b31-11ec-b3df-0242ac110002 UniProtKB:B2V8E3 biolink:molecularly_interacts_with DrugCentral:2872 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zonisamide targets Enzyme (Carbonate dehydratase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:60586ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:605953ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.176']} DrugCentral uuid:605953ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.176']} DrugCentral uuid:605953ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.176']} DrugCentral uuid:60599cf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:60599cf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:60599cf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31644 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-5/beta-3/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:6059e5a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:6059e5a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:6059e5a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:605a303a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:605a303a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:605a303a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.582']} DrugCentral uuid:605a7ab8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:605a7ab8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:605a7ab8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.488']} DrugCentral uuid:605ac4b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:605ac4b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:605ac4b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-3/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:605b0d3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:605b0d3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:605b0d3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.278']} DrugCentral uuid:605b567c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:605b567c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:605b567c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:2873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zopiclone is positive modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:605b9894-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.394']} DrugCentral uuid:605bc17a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.638']} DrugCentral uuid:605bea42-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.54']} DrugCentral uuid:605c14b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:605c3d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.686']} DrugCentral uuid:605c6652-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.821']} DrugCentral uuid:605c8f92-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:605cb85a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:605ce140-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.04']} DrugCentral uuid:605d0a44-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:605d33ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:605d5c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:605d8578-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.155']} DrugCentral uuid:605dae4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.273']} DrugCentral uuid:605dd96a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.19']} DrugCentral uuid:605e0480-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.606']} DrugCentral uuid:605e2e42-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.21']} DrugCentral uuid:605e5732-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.301']} DrugCentral uuid:605e807c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.704']} DrugCentral uuid:605ea93a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.745']} DrugCentral uuid:605ed2ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:605efb74-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.137']} DrugCentral uuid:605f250e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:605f4dd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.585']} DrugCentral uuid:605f76a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:605fa0b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:605fca22-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.016']} DrugCentral uuid:605ff2f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.441']} DrugCentral uuid:60601bd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.41']} DrugCentral uuid:6060451a-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.326']} DrugCentral uuid:60606dd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.301']} DrugCentral uuid:606096b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:6060bf7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:6060e920-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:606111fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:2875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotepine is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:60613ad8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol targets GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:60615f4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:606188f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol targets GPCR (Alpha-1A adrenergic receptor) DrugCentral uuid:6061ad7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol is antagonist of GPCR (D(1A) dopamine receptor) DrugCentral uuid:6061d20e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:2877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zuclopenthixol is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:6061f694-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00975 biolink:molecularly_interacts_with DrugCentral:2878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziconotide is blocker of Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) DrugCentral uuid:60621e6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02294 biolink:molecularly_interacts_with DrugCentral:2878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziconotide is blocker of Ion channel (Voltage-dependent N-type calcium channel subunit alpha-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.3']} DrugCentral uuid:6062495a-6b31-11ec-b3df-0242ac110002 UniProtKB:P54282 biolink:molecularly_interacts_with DrugCentral:2878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ziconotide is blocker of Ion channel (Voltage-dependent P/Q-type calcium channel subunit alpha-1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:6062722c-6b31-11ec-b3df-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:2949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotarolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:60629afe-6b31-11ec-b3df-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:2949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zotarolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:6062c434-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:2955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eledoisin is agonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:6062ecfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P29371 biolink:molecularly_interacts_with DrugCentral:2955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eledoisin targets GPCR (Neuromedin-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.66']} DrugCentral uuid:606315d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:2958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gonadorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:60633eb4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:2958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gonadorelin targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:60636b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P16235 biolink:molecularly_interacts_with DrugCentral:2958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gonadorelin targets GPCR (Lutropin-choriogonadotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:60639f6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lypressin is agonist of GPCR (Vasopressin receptor) DrugCentral uuid:60639f6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lypressin is agonist of GPCR (Vasopressin receptor) DrugCentral uuid:60639f6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:2959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lypressin is agonist of GPCR (Vasopressin receptor) DrugCentral uuid:6063d96e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC29 biolink:molecularly_interacts_with DrugCentral:2960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mifamurtide is activator of Cytosolic other (Nucleotide-binding oligomerization domain-containing protein 2) DrugCentral uuid:6063febc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96EB6 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (NAD-dependent protein deacetylase sirtuin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:6064278e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15077 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kb', 'has_quantitative_value': ['4']} DrugCentral uuid:60645060-6b31-11ec-b3df-0242ac110002 UniProtKB:P47900 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:6064793c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IXJ6 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (NAD-dependent protein deacetylase sirtuin-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:6064a27c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:6064cb4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96G91 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:6064f416-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:60651e00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BPV8 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of GPCR (P2Y purinoceptor 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:6065488a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:60657152-6b31-11ec-b3df-0242ac110002 UniProtKB:P78527 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (DNA-dependent protein kinase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:60659a9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5VLE3 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (RmtA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:6065c404-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99571 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Ion channel (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.749']} DrugCentral uuid:6065ecd6-6b31-11ec-b3df-0242ac110002 UniProtKB:O15648 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (ATP-dependent 6-phosphofructokinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:60663b64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:60663b64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:60663b64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:60663b64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:60663b64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:60663b64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:60663b64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:60663b64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:60663b64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:60663b64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:60663b64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:6066dccc-6b31-11ec-b3df-0242ac110002 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.963']} DrugCentral uuid:60670756-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NXA8 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (NAD-dependent protein deacylase sirtuin-5, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:60673046-6b31-11ec-b3df-0242ac110002 UniProtKB:Q80Z26 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (Nucleoside triphosphate diphosphohydrolase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:60675940-6b31-11ec-b3df-0242ac110002 UniProtKB:O35795 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Enzyme (Ectonucleoside triphosphate diphosphohydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.18']} DrugCentral uuid:60678226-6b31-11ec-b3df-0242ac110002 UniProtKB:P49654 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:6067ab5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P49653 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:6067d42e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47824 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:6067fe4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P51578 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin is antagonist of Unclassified (P2X purinoceptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:60682794-6b31-11ec-b3df-0242ac110002 UniProtKB:P42224 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Unclassified (Signal transducer and activator of transcription 1-alpha/beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.04']} DrugCentral uuid:60685098-6b31-11ec-b3df-0242ac110002 UniProtKB:P42229 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Unclassified (Signal transducer and activator of transcription 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:60687988-6b31-11ec-b3df-0242ac110002 UniProtKB:P51692 biolink:molecularly_interacts_with DrugCentral:2966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suramin targets Unclassified (Signal transducer and activator of transcription 5B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.98']} DrugCentral uuid:6068a25a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:2968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triptorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.025']} DrugCentral uuid:6068cca8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:2968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triptorelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:6068f584-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium targets GPCR (Muscarinic acetylcholine receptor M2) DrugCentral uuid:606919f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15822 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium targets Ion channel (Neuronal acetylcholine receptor subunit alpha-2) DrugCentral uuid:60694728-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:60694728-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:60694728-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:2974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doxacurium is antagonist of Ion channel (Acetylcholine receptor) DrugCentral uuid:6069810c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:2975 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 histrelin is agonist of GPCR (Gonadotropin-releasing hormone receptor) DrugCentral uuid:6069a5b0-6b31-11ec-b3df-0242ac110002 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:2977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caspofungin is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:6069cea0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4WLT4 biolink:molecularly_interacts_with DrugCentral:2977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caspofungin is inhibitor of Enzyme (1,3-beta-glucan synthase catalytic subunit FksP) DrugCentral uuid:6069f344-6b31-11ec-b3df-0242ac110002 UniProtKB:O13383 biolink:molecularly_interacts_with DrugCentral:2977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caspofungin targets Unclassified (1,3-beta-D-glucan synthase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:606a206c-6b31-11ec-b3df-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.65']} DrugCentral uuid:606a206c-6b31-11ec-b3df-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.65']} DrugCentral uuid:606a5956-6b31-11ec-b3df-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.873']} DrugCentral uuid:606a5956-6b31-11ec-b3df-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.873']} DrugCentral uuid:606a9236-6b31-11ec-b3df-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.499']} DrugCentral uuid:606a9236-6b31-11ec-b3df-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.499']} DrugCentral uuid:606aca62-6b31-11ec-b3df-0242ac110002 UniProtKB:P30988 biolink:molecularly_interacts_with DrugCentral:2989 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin (salmon synthetic) is agonist of GPCR (Calcitonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.086']} DrugCentral uuid:606af33e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desirudin is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['12.7']} DrugCentral uuid:606b1c2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:606b4582-6b31-11ec-b3df-0242ac110002 UniProtKB:P47871 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon is agonist of GPCR (Glucagon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:606b6e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30082 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets GPCR (Glucagon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:606bb1e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:606bb1e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:606bb1e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:606bb1e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:606bb1e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:606bb1e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:606bb1e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:606bb1e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8CFM9 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets Enzyme (Adenylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:606c30aa-6b31-11ec-b3df-0242ac110002 UniProtKB:F8V479 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.51']} DrugCentral uuid:606c5954-6b31-11ec-b3df-0242ac110002 UniProtKB:O35659 biolink:molecularly_interacts_with DrugCentral:2994 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glucagon targets GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.36']} DrugCentral uuid:606c84ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:2995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lepirudin is inhibitor of Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['13']} DrugCentral uuid:606cae0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:606cd6cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:606cff94-6b31-11ec-b3df-0242ac110002 UniProtKB:P30875 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.55']} DrugCentral uuid:606d28c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30935 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.1']} DrugCentral uuid:606d5188-6b31-11ec-b3df-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:606d8ab8-6b31-11ec-b3df-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:606d8ab8-6b31-11ec-b3df-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:606d8ab8-6b31-11ec-b3df-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:606d8ab8-6b31-11ec-b3df-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:606d8ab8-6b31-11ec-b3df-0242ac110002 UniProtKB:P49660 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:606df32c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:606df32c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:606df32c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:606df32c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:606df32c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30938 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin targets GPCR (Somatostatin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:606e4c82-6b31-11ec-b3df-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.46']} DrugCentral uuid:606e75a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:606e9e8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:606ec78e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31391 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.23']} DrugCentral uuid:606ef0f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:2997 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatostatin is agonist of GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.54']} DrugCentral uuid:606f19d2-6b31-11ec-b3df-0242ac110002 UniProtKB:O96529 biolink:molecularly_interacts_with DrugCentral:2999 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrantel targets Enzyme (Acetylcholinesterase) DrugCentral uuid:606f3e4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:606f6720-6b31-11ec-b3df-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban targets GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.36']} DrugCentral uuid:606f91c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:606fbab8-6b31-11ec-b3df-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:606fe3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:3008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atosiban is antagonist of GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:60700cca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel protein type 10 subunit alpha) DrugCentral uuid:60703ace-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:60703ace-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:60703ace-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybuprocaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:60707b88-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.934']} DrugCentral uuid:6070a48c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.051']} DrugCentral uuid:6070cde0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.888']} DrugCentral uuid:6070f6da-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.046']} DrugCentral uuid:60711fb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.432']} DrugCentral uuid:607148b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.269']} DrugCentral uuid:6071724a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.532']} DrugCentral uuid:60719bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.004']} DrugCentral uuid:6071c48e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:6071ee6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.092']} DrugCentral uuid:6072175e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.444']} DrugCentral uuid:60724030-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:60726902-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.545']} DrugCentral uuid:60729242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.965']} DrugCentral uuid:6072bb64-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.649']} DrugCentral uuid:6072e422-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.115']} DrugCentral uuid:60730cea-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.681']} DrugCentral uuid:6073365c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.192']} DrugCentral uuid:60736136-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.155']} DrugCentral uuid:60738a30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q969F8 biolink:molecularly_interacts_with DrugCentral:3018 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzethonium targets GPCR (KiSS-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:6073b30c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bergapten targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:6073de9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63470 biolink:molecularly_interacts_with DrugCentral:3021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bergapten targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:6074076c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04798 biolink:molecularly_interacts_with DrugCentral:3021 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bergapten targets Enzyme (Cytochrome P450 1A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:6074305c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bietamiverine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.57']} DrugCentral uuid:60745942-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bietamiverine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.99']} DrugCentral uuid:6074828c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bietamiverine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:6074ab54-6b31-11ec-b3df-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.299']} DrugCentral uuid:6074d426-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.651']} DrugCentral uuid:6074fdca-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.184']} DrugCentral uuid:607526a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.843']} DrugCentral uuid:60754fa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.912']} DrugCentral uuid:60757890-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.501']} DrugCentral uuid:6075a31a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.365']} DrugCentral uuid:6075cbf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.337']} DrugCentral uuid:6075f4dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:60761dc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.844']} DrugCentral uuid:607647a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.195']} DrugCentral uuid:60767088-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.761']} DrugCentral uuid:60769978-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:6076c25e-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:6076ec0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:60771506-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.212']} DrugCentral uuid:60773df6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.647']} DrugCentral uuid:60776862-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.668']} DrugCentral uuid:60779454-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.735']} DrugCentral uuid:6077bd30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.498']} DrugCentral uuid:6077e60c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:60780f74-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.809']} DrugCentral uuid:6078385a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.415']} DrugCentral uuid:60786118-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:607889ea-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6078b334-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:6078dc10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:607904e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O75751 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Transporter (Solute carrier family 22 member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:60792daa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:607957da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol targets Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:607980ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z258 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol is activator of Ion channel (Potassium channel subfamily T member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:6079a99c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6IQ20 biolink:molecularly_interacts_with DrugCentral:3032 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bithionol is inhibitor of Unclassified (N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:6079d282-6b31-11ec-b3df-0242ac110002 UniProtKB:P04183 biolink:molecularly_interacts_with DrugCentral:3042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 broxuridine targets Kinase (Thymidine kinase, cytosolic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:6079fc1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WKE1 biolink:molecularly_interacts_with DrugCentral:3042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 broxuridine targets Kinase (Thymidylate kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:607a262e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:3047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufexamac is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.97']} DrugCentral uuid:607a4f1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:3047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufexamac is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.91']} DrugCentral uuid:607a78a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:3047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufexamac targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:607aa158-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IEK1 biolink:molecularly_interacts_with DrugCentral:3047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufexamac targets Enzyme (M1-family alanyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:607ad1dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:607ad1dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:607ad1dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:607b1be2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butethamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:607b1be2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butethamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:607b1be2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3053 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butethamine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.26']} DrugCentral uuid:607b5dd2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is opener of Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:607b86c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:607bb048-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:607bd924-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:607c01e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09470 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:607c2ac8-6b31-11ec-b3df-0242ac110002 UniProtKB:P54577 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Tyrosine--tRNA ligase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:607c54b2-6b31-11ec-b3df-0242ac110002 UniProtKB:O35433 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:607c7db6-6b31-11ec-b3df-0242ac110002 UniProtKB:P03887 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Unclassified (NADH-ubiquinone oxidoreductase chain 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:607ca700-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R4D5 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:607cd004-6b31-11ec-b3df-0242ac110002 UniProtKB:Q704Y3 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is activator of Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8']} DrugCentral uuid:607cf9ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:607d22c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P16388 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:607d4b88-6b31-11ec-b3df-0242ac110002 UniProtKB:P63142 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.4']} DrugCentral uuid:607d7478-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capsaicin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.25']} DrugCentral uuid:607d9dae-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:607dc680-6b31-11ec-b3df-0242ac110002 UniProtKB:P23795 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:607def52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NJH6 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Unclassified (Ace-orthologous acetylcholinesterase; Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:607e1842-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7YWJ9 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:607e41c8-6b31-11ec-b3df-0242ac110002 UniProtKB:K4JQ36 biolink:molecularly_interacts_with DrugCentral:3066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbaryl targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:607e6a90-6b31-11ec-b3df-0242ac110002 UniProtKB:P05181 biolink:molecularly_interacts_with DrugCentral:3067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbon tetrachloride targets Enzyme (Cytochrome P450 2E1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.959']} DrugCentral uuid:607e9358-6b31-11ec-b3df-0242ac110002 UniProtKB:P31327 biolink:molecularly_interacts_with DrugCentral:3068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carglumic acid is positive allosteric modulator of Enzyme (Carbamoyl-phosphate synthase [ammonia], mitochondrial) DrugCentral uuid:607ec094-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3070 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 articaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:607ec094-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3070 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 articaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:607ec094-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3070 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 articaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:607f0270-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05193 biolink:molecularly_interacts_with DrugCentral:3082 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetrimonium targets Structural (Dynamin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:607f2b38-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:3083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetylpyridinium targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:607f5400-6b31-11ec-b3df-0242ac110002 UniProtKB:P42575 biolink:molecularly_interacts_with DrugCentral:3083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetylpyridinium targets Enzyme (Caspase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:607f7d2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxylenol targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.928']} DrugCentral uuid:607fa608-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chloroxylenol targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.738']} DrugCentral uuid:607fceda-6b31-11ec-b3df-0242ac110002 UniProtKB:P10845 biolink:molecularly_interacts_with DrugCentral:3095 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorquinaldol targets Enzyme (Botulinum neurotoxin type A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:607ff81a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:3096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cholic acid targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:608020f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:3096 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cholic acid is agonist of GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:608049b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:608073e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:6080a274-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:6080a274-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha2/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.74']} DrugCentral uuid:6080dc76-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:6080dc76-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:60811538-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:60811538-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha3/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.32']} DrugCentral uuid:60814eb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:60814eb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P12390 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.43']} DrugCentral uuid:6081877a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:6081877a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12392 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Ion channel (Neuronal acetylcholine receptor; alpha4/beta4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:6081bc5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28570 biolink:molecularly_interacts_with DrugCentral:3097 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline targets Transporter (Creatine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:6081e5c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:3101 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinchophen targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['3.9']} DrugCentral uuid:60820fe2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q695T7 biolink:molecularly_interacts_with DrugCentral:3102 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cinromide is inhibitor of Transporter (Sodium-dependent neutral amino acid transporter B(0)AT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:60823940-6b31-11ec-b3df-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:3111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorindione targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:60826212-6b31-11ec-b3df-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:3114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxiquine targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:60828ddc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:3114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxiquine targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:6082b6c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:3114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cloxiquine targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:6082e75a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclomethycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:6082e75a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclomethycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:6082e75a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyclomethycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:608328e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:3124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cynarine targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:608351c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P70536 biolink:molecularly_interacts_with DrugCentral:3126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 demoxytocin targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:608385fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:608385fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:608385fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:608385fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desomorphine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:6083d32c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:6083f7b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibrompropamidine targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:608420a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibrompropamidine targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:60844b7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:3137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibrompropamidine targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.27']} DrugCentral uuid:6084744e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08001 biolink:molecularly_interacts_with DrugCentral:3137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibrompropamidine targets Enzyme (Acrosin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:60849d48-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 difluprednate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:6084c994-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinisocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:6084c994-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinisocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:6084c994-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinisocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:60850ae4-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:608533ac-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:60855d8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:3158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dioxadrol targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:6085874e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q39829 biolink:molecularly_interacts_with DrugCentral:3162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disufenton targets Unclassified (Lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:6085b020-6b31-11ec-b3df-0242ac110002 UniProtKB:Q39829 biolink:molecularly_interacts_with DrugCentral:3162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 disufenton targets Unclassified (Lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:6085d91a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:3165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domitroban is antagonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:60860340-6b31-11ec-b3df-0242ac110002 UniProtKB:P30987 biolink:molecularly_interacts_with DrugCentral:3165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 domitroban is antagonist of GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:60862df2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:608656d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.2']} DrugCentral uuid:60867fd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:6086a8cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eburnamonine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.6']} DrugCentral uuid:6086d23e-6b31-11ec-b3df-0242ac110002 UniProtKB:A3RLP8 biolink:molecularly_interacts_with DrugCentral:3173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edoxudine targets Kinase (Thymidine kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:6086fb06-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:608723d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:60874d22-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:608775ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:60879ed0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:6087c7ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:6087f222-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:60881aea-6b31-11ec-b3df-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:60884452-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDS5 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets GPCR (Oxoeicosanoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:60886d2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:3174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eicosapentaenoic acid targets Nuclear other (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:608896dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:3177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enilconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:6088bfd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:6088e8b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:608911a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23141 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Liver carboxylesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:60893bfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P24723 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Kinase (Protein kinase C eta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:608964d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P80365 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.91']} DrugCentral uuid:60898da8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28845 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:6089b67a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00489 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Glycogen phosphorylase, muscle form) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:6089e15e-6b31-11ec-b3df-0242ac110002 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:608a0a3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50172 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:608a330c-6b31-11ec-b3df-0242ac110002 UniProtKB:O60218 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Aldo-keto reductase family 1 member B10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:608a5c88-6b31-11ec-b3df-0242ac110002 UniProtKB:P16232 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:608a856e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50233 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Corticosteroid 11-beta-dehydrogenase isozyme 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:608aae4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06124 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Tyrosine-protein phosphatase non-receptor type 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:608ad726-6b31-11ec-b3df-0242ac110002 UniProtKB:P29350 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Protein-tyrosine phosphatase 1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:608b0066-6b31-11ec-b3df-0242ac110002 UniProtKB:P09429 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Nuclear other (High mobility group protein B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.06']} DrugCentral uuid:608b296a-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:608b5228-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9CPU0 biolink:molecularly_interacts_with DrugCentral:3178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxolone targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.54']} DrugCentral uuid:608b7b04-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eseridine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:608ba62e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:3186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eseridine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:608bcee2-6b31-11ec-b3df-0242ac110002 UniProtKB:P04058 biolink:molecularly_interacts_with DrugCentral:3186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eseridine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:608bf7aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:608c209a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.748']} DrugCentral uuid:608c4a48-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:608c7324-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol is agonist of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:608c9c00-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:608cc54a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.63']} DrugCentral uuid:608cef98-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.064']} DrugCentral uuid:608d1888-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPP9 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:608d4268-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:3187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estriol targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:608d6cc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.55']} DrugCentral uuid:608d9736-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.062']} DrugCentral uuid:608dc044-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:608de902-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:608e1288-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:608e3b64-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:608e6440-6b31-11ec-b3df-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Enzyme (Steryl-sulfatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:608e8cfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.18']} DrugCentral uuid:608eb648-6b31-11ec-b3df-0242ac110002 UniProtKB:P14061 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Enzyme (Estradiol 17-beta-dehydrogenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:608edf24-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.111']} DrugCentral uuid:608f080a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.181']} DrugCentral uuid:608f30be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.678']} DrugCentral uuid:608f5c60-6b31-11ec-b3df-0242ac110002 UniProtKB:O14746 biolink:molecularly_interacts_with DrugCentral:3194 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacridine targets Enzyme (Telomerase reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:608f8532-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:3194 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethacridine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:608fae18-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:608fd794-6b31-11ec-b3df-0242ac110002 UniProtKB:P42261 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.13']} DrugCentral uuid:60900098-6b31-11ec-b3df-0242ac110002 UniProtKB:P39086 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.75']} DrugCentral uuid:609029b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P42262 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.91']} DrugCentral uuid:609052a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16478 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:60907bd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.77']} DrugCentral uuid:6090a4d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13002 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:6090cdc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13003 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:6090f69c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19491 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:609120d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P42263 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:60914aa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16099 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:60917388-6b31-11ec-b3df-0242ac110002 UniProtKB:P42260 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.43']} DrugCentral uuid:60919c50-6b31-11ec-b3df-0242ac110002 UniProtKB:P22756 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:6091c5d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P19490 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.32']} DrugCentral uuid:6091eec6-6b31-11ec-b3df-0242ac110002 UniProtKB:P19492 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:609217a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:6092409c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01812 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.33']} DrugCentral uuid:609269e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:609292b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P42264 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:6092c71a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:6092c71a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:6092c71a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:6092c71a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19493 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:60932872-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:60932872-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:60932872-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:60932872-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:60932872-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63273 biolink:molecularly_interacts_with DrugCentral:3201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kainic acid targets Ion channel (Glutamate receptor ionotropic, kainate) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.37']} DrugCentral uuid:60938aa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordefrin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:60938aa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordefrin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:60938aa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nordefrin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:6093e244-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:6093e244-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:6093e244-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:6093e244-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:6093e244-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:6093e244-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:6093e244-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:3215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoxadrol targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:60945454-6b31-11ec-b3df-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:60947d58-6b31-11ec-b3df-0242ac110002 UniProtKB:P25044 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Enzyme (Tyrosine-protein phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:6094a620-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7TSF2 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Transporter (Vesicular glutamate transporter 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:6094d168-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13822 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Enzyme (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:6094fa4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08659 biolink:molecularly_interacts_with DrugCentral:3217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evans blue targets Unclassified (Luciferin 4-monooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:60952320-6b31-11ec-b3df-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:3219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exisulind targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.217']} DrugCentral uuid:60954c10-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:3219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exisulind targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:60957582-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:3219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 exisulind targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.859']} DrugCentral uuid:60959e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.229']} DrugCentral uuid:6095c730-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.959']} DrugCentral uuid:6095f084-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.119']} DrugCentral uuid:60961956-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.641']} DrugCentral uuid:60964232-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.377']} DrugCentral uuid:60966b22-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.036']} DrugCentral uuid:60969570-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.824']} DrugCentral uuid:6096beba-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.658']} DrugCentral uuid:6096e782-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.328']} DrugCentral uuid:6097105e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.398']} DrugCentral uuid:609739bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.688']} DrugCentral uuid:609762a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61327 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.04']} DrugCentral uuid:60978b7e-6b31-11ec-b3df-0242ac110002 UniProtKB:O55192 biolink:molecularly_interacts_with DrugCentral:3220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 femoxetine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:6097b45a-6b31-11ec-b3df-0242ac110002 UniProtKB:P05121 biolink:molecularly_interacts_with DrugCentral:3224 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fendosal is inhibitor of Secreted (Plasminogen activator inhibitor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.824']} DrugCentral uuid:6097de94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:3225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenoxazoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:609807a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P04303 biolink:molecularly_interacts_with DrugCentral:3227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenticlor targets Enzyme (Uracil-DNA glycosylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:60983060-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:3229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fumaric acid targets Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.72']} DrugCentral uuid:60985950-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:3236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flusalan targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:60988452-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:3236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flusalan targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.07']} DrugCentral uuid:6098ad10-6b31-11ec-b3df-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:3236 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flusalan targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:6098d9c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfestrol is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:6098d9c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosfestrol is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:60993834-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:3249 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fospropofol is positive allosteric modulator of Ion channel (GABA-A receptor) DrugCentral uuid:6099d988-6b31-11ec-b3df-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:3253 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fumagillin targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.2']} DrugCentral uuid:609a0250-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:609a2b54-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.5']} DrugCentral uuid:609a5700-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:609a7ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 furtrethonium is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:609aa976-6b31-11ec-b3df-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:609ad310-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:609afcd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:609b25b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:609b4e94-6b31-11ec-b3df-0242ac110002 UniProtKB:P00750 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Tissue-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.81']} DrugCentral uuid:609b77ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:609ba07e-6b31-11ec-b3df-0242ac110002 UniProtKB:O08590 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Membrane primary amine oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:609bc95a-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:609bf218-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:609c1c5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.97']} DrugCentral uuid:609c454c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15661 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate is inhibitor of Enzyme (Tryptase alpha/beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:609c6e1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05981 biolink:molecularly_interacts_with DrugCentral:3257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabexate targets Enzyme (Serine protease hepsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:609c96e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:609cc044-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:609ce920-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:609d1206-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:609d3af6-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:609d6440-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:609d8d08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentisic acid targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:609db5ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.84']} DrugCentral uuid:609de03c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:609e0c06-6b31-11ec-b3df-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:609e34e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.03']} DrugCentral uuid:609e5ddc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:3275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hexamidine targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:609e883e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:609eb142-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:609eda14-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:609f02fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.49']} DrugCentral uuid:609f2d48-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:609f5638-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:609f7f32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:609fa822-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:609fd284-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.38']} DrugCentral uuid:609ffb6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:60a024dc-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.91']} DrugCentral uuid:60a04e1c-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:60a076f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:60a09fd4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:3282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroquinone targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:60a0c8ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['3.89']} DrugCentral uuid:60a0f1e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:60a11ac2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50579 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Methionine aminopeptidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:60a14394-6b31-11ec-b3df-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:60a16c52-6b31-11ec-b3df-0242ac110002 UniProtKB:P53582 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Methionine aminopeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:60a19768-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01693 biolink:molecularly_interacts_with DrugCentral:3290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxyquinoline targets Enzyme (Bacterial leucyl aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:60a1c38c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:3293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibufenac targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:60a1ef7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.67']} DrugCentral uuid:60a218c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.969']} DrugCentral uuid:60a241ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:60a26ae4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:60a293b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:60a2bc7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.181']} DrugCentral uuid:60a2e5d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.859']} DrugCentral uuid:60a30ec2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.227']} DrugCentral uuid:60a338a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.37']} DrugCentral uuid:60a362fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:60a38eec-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:60a3b804-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.79']} DrugCentral uuid:60a3e0e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.15']} DrugCentral uuid:60a40a2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.496']} DrugCentral uuid:60a4334c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.91']} DrugCentral uuid:60a45c1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:60a484fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:60a4ae4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:60a4d72a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:60a5001a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:60a528d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.79']} DrugCentral uuid:60a55312-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:60a57d42-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:60a5a628-6b31-11ec-b3df-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:60a5cf86-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:60a5f858-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:60a62134-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:60a64a24-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:60a67364-6b31-11ec-b3df-0242ac110002 UniProtKB:Q64264 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:60a69c40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q61616 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:60a6c512-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75Z89 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:60a6edee-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone is antagonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:60a72160-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:60a72160-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:60a72160-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3294 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iloperidone targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:60a76440-6b31-11ec-b3df-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:3309 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoconazole targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:60a78d12-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:3309 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isoconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:60a7b670-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:60a7df4c-6b31-11ec-b3df-0242ac110002 UniProtKB:O88704 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:60a80832-6b31-11ec-b3df-0242ac110002 UniProtKB:O88703 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine targets Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:60a8310e-6b31-11ec-b3df-0242ac110002 UniProtKB:O60741 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:60a85a76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL51 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) DrugCentral uuid:60a87f10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P1Z3 biolink:molecularly_interacts_with DrugCentral:3312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivabradine is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:60a8a81e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04798 biolink:molecularly_interacts_with DrugCentral:3313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 khellin targets Enzyme (Cytochrome P450 1A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:60a8d0fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:3317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenalidomide targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.886']} DrugCentral uuid:60a8fd96-6b31-11ec-b3df-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:3317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:60a92898-6b31-11ec-b3df-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:3317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:60a9519c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:3317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenalidomide is modulator of Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.527']} DrugCentral uuid:60a97adc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:60a9a3b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.32']} DrugCentral uuid:60a9cc8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:60a9f57a-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:60aa1eb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15090 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Cytosolic other (Fatty acid-binding protein, adipocyte) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60aa4796-6b31-11ec-b3df-0242ac110002 UniProtKB:P05413 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Cytosolic other (Fatty acid-binding protein, heart) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:60aa7072-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:60aa9944-6b31-11ec-b3df-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:60aac48c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14721 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid is activator of Ion channel (Potassium voltage-gated channel subfamily B member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:60aaee6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.19']} DrugCentral uuid:60ab172a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08170 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Enzyme (Seed linoleate 13S-lipoxygenase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60ab3fde-6b31-11ec-b3df-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.39']} DrugCentral uuid:60ab6932-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:60ab91fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5NUL3 biolink:molecularly_interacts_with DrugCentral:3323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linoleic acid is agonist of GPCR (Free fatty acid receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:60abbae0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:3325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lodoxamide is agonist of GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.793']} DrugCentral uuid:60abe3a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:3328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lubeluzole targets Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:60ac0e1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P62157 biolink:molecularly_interacts_with DrugCentral:3328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lubeluzole targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:60ac3704-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestanolone is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:60ac5b8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mestanolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.81']} DrugCentral uuid:60ac8592-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesterolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.6']} DrugCentral uuid:60acaf0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mesterolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:60acd7f4-6b31-11ec-b3df-0242ac110002 UniProtKB:O34667 biolink:molecularly_interacts_with DrugCentral:3347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methionine targets Unclassified (S-ribosylhomocysteine lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.21']} DrugCentral uuid:60ad00c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.077']} DrugCentral uuid:60ad2a2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.66']} DrugCentral uuid:60ad52ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.43']} DrugCentral uuid:60ad7bfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:60ada4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyltestosterone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:60adcdee-6b31-11ec-b3df-0242ac110002 UniProtKB:P17708 biolink:molecularly_interacts_with DrugCentral:3362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoguazone targets Enzyme (S-adenosylmethionine decarboxylase proenzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60adf6ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P36633 biolink:molecularly_interacts_with DrugCentral:3362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mitoguazone targets Enzyme (Amiloride-sensitive amine oxidase [copper-containing]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:60ae235c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxestrol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:60ae235c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxestrol targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:60ae5944-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.68']} DrugCentral uuid:60ae8252-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:60aeab38-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:60aed518-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:60aefe4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:60af2edc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:60af2edc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:60af2edc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:60af773e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:60af773e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:60af773e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:60afcb6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:60afcb6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:60afcb6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:60afcb6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:60afcb6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:60afcb6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3369 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naphazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:60b0311a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:3377 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neridronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:60b05a14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:3380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nifenalol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.88']} DrugCentral uuid:60b082f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:60b0abb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:60b0d4d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:60b0fda2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:60b1267e-6b31-11ec-b3df-0242ac110002 UniProtKB:H9TVJ1 biolink:molecularly_interacts_with DrugCentral:3396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octopamine targets GPCR (TyR1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:60b14f5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01705 biolink:molecularly_interacts_with DrugCentral:3399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleandrin targets Unclassified (Neurogenic locus notch homolog protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:60b178b8-6b31-11ec-b3df-0242ac110002 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.22']} DrugCentral uuid:60b1a1bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:60b1ca84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:60b1f55e-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:60b221c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15090 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Cytosolic other (Fatty acid-binding protein, adipocyte) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:60b24b3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:60b273f8-6b31-11ec-b3df-0242ac110002 UniProtKB:O14746 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (Telomerase reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:60b29d10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01469 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Cytosolic other (Fatty acid-binding protein, epidermal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.61']} DrugCentral uuid:60b2c682-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.28']} DrugCentral uuid:60b2ef5e-6b31-11ec-b3df-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:60b31826-6b31-11ec-b3df-0242ac110002 UniProtKB:P07148 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:60b34170-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:60b36ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08170 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Enzyme (Seed linoleate 13S-lipoxygenase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:60b393b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:60b3bc86-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5NUL3 biolink:molecularly_interacts_with DrugCentral:3400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oleic acid is agonist of GPCR (Free fatty acid receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:60b3e79c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5T6X5 biolink:molecularly_interacts_with DrugCentral:3401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ornithine is agonist of GPCR (G-protein coupled receptor family C group 6 member A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:60b41884-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxetacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:60b41884-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxetacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:60b41884-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3407 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxetacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:60b45948-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.684']} DrugCentral uuid:60b482a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.815']} DrugCentral uuid:60b4ab8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.046']} DrugCentral uuid:60b4d47c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.372']} DrugCentral uuid:60b4fd94-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.723']} DrugCentral uuid:60b526de-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:60b54fce-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.925']} DrugCentral uuid:60b578b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.533']} DrugCentral uuid:60b5a28a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.778']} DrugCentral uuid:60b5cd3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.169']} DrugCentral uuid:60b5f62c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.943']} DrugCentral uuid:60b61f1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.018']} DrugCentral uuid:60b6487a-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.449']} DrugCentral uuid:60b6716a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:60b69a5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.676']} DrugCentral uuid:60b6c336-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60b6ec62-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.445']} DrugCentral uuid:60b71552-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:60b739ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.728']} DrugCentral uuid:60b762be-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.333']} DrugCentral uuid:60b78d98-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:60b7b9da-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.398']} DrugCentral uuid:60b7e540-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.209']} DrugCentral uuid:60b80e08-6b31-11ec-b3df-0242ac110002 UniProtKB:P14902 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets Enzyme (Indoleamine 2,3-dioxygenase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:60b83748-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.969']} DrugCentral uuid:60b86038-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxiconazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:60b88aea-6b31-11ec-b3df-0242ac110002 UniProtKB:P15304 biolink:molecularly_interacts_with DrugCentral:3412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxybenzone targets Enzyme (Hormone-sensitive lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:60b8b3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:3413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycinchophen targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:60b8dd06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y233 biolink:molecularly_interacts_with DrugCentral:3413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxycinchophen targets Enzyme (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.82']} DrugCentral uuid:60b905e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.409']} DrugCentral uuid:60b92ee6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine is modulator of Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.76']} DrugCentral uuid:60b9592a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.658']} DrugCentral uuid:60b98530-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.307']} DrugCentral uuid:60b9af10-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.16']} DrugCentral uuid:60b9d80a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.12']} DrugCentral uuid:60ba0172-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:60ba2a6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.27']} DrugCentral uuid:60ba5eb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:60ba5eb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:60ba5eb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:60ba5eb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:3424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pentazocine targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:60bab374-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:60bab374-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:60bab374-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenacaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:60baf410-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3467 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picloxydine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:60bb1d14-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:3467 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 picloxydine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:60bb496a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VC69 biolink:molecularly_interacts_with DrugCentral:3474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adipic acid targets Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:60bb72b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.222']} DrugCentral uuid:60bb9b7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:60bbc4a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.398']} DrugCentral uuid:60bbeda2-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.301']} DrugCentral uuid:60bc167e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04015 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Unclassified (Regulatory protein E2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.7']} DrugCentral uuid:60bc3f82-6b31-11ec-b3df-0242ac110002 UniProtKB:P02550 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:60bc68cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P03118 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Unclassified (Regulatory protein E2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.98']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bcc68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B7 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60bda41c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:60bda41c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:60bda41c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q862L2 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.34']} DrugCentral uuid:60bde8aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:60bde8aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P02554 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Structural (Tubulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:60be1d98-6b31-11ec-b3df-0242ac110002 UniProtKB:P03120 biolink:molecularly_interacts_with DrugCentral:3481 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 podophyllotoxin targets Unclassified (Human papillomavirus regulatory protein E2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.15']} DrugCentral uuid:60be46f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:3482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polyestradiol phosphate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:60be6b72-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:60be9002-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'MIC', 'has_quantitative_value': ['9.398']} DrugCentral uuid:60beb8fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4WNT5 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (14-alpha sterol demethylase Cyp51A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:60bee430-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96W81 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (14-alpha sterol demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:60bf10a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7Z1V1 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (Sterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:60bf3c8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNU6 biolink:molecularly_interacts_with DrugCentral:3483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 posaconazole targets Enzyme (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:60bf6784-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:60bf90c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:60bfbaa4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.69']} DrugCentral uuid:60bfe36c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18090 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:60c00cd4-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.98']} DrugCentral uuid:60c035a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18762 biolink:molecularly_interacts_with DrugCentral:3486 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 practolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.87']} DrugCentral uuid:60c05e8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.292']} DrugCentral uuid:60c0877c-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.199']} DrugCentral uuid:60c0ba30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:60c0ba30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:60c0ba30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3487 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pramocaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:60c0fad6-6b31-11ec-b3df-0242ac110002 UniProtKB:P07477 biolink:molecularly_interacts_with DrugCentral:3493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propamidine targets Enzyme (Trypsin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.48']} DrugCentral uuid:60c123b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08001 biolink:molecularly_interacts_with DrugCentral:3493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propamidine targets Enzyme (Acrosin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.46']} DrugCentral uuid:60c154c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propoxycaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:60c154c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propoxycaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:60c154c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 propoxycaine is blocker of Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:60c19572-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XUB2 biolink:molecularly_interacts_with DrugCentral:3500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protoporphyrin targets Cytosolic other (Zinc finger protein mex-5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:60c1be26-6b31-11ec-b3df-0242ac110002 UniProtKB:G5EF15 biolink:molecularly_interacts_with DrugCentral:3500 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 protoporphyrin targets Unclassified (Cytoplasmic zinc-finger protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:60c1e734-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prucalopride targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.629']} DrugCentral uuid:60c21006-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:3502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prucalopride targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:60c238d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:3502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prucalopride targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.58']} DrugCentral uuid:60c261aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:3502 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prucalopride is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:60c28c84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:3505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 homonicotinic acid is agonist of GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:60c2b650-6b31-11ec-b3df-0242ac110002 UniProtKB:P51575 biolink:molecularly_interacts_with DrugCentral:3506 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxal phosphate targets Ion channel (P2X purinoceptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:60c2df22-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:60c307fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:60c33166-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:60c35b3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:60c38418-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:60c3ae2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:60c3d7ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:60c400aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:60c42990-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:60c4542e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:60c47e18-6b31-11ec-b3df-0242ac110002 UniProtKB:P55789 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (FAD-linked sulfhydryl oxidase ALR) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:60c4a6e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28300 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Protein-lysine 6-oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:60c4cfb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P58215 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Lysyl oxidase homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:60c4f8d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96JB6 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Lysyl oxidase homolog 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:60c521ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K0 biolink:molecularly_interacts_with DrugCentral:3508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione targets Enzyme (Lysyl oxidase homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:60c54a82-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:3511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrovalerone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:60c5735e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrovalerone targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:60c59cf8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3511 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrovalerone targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.1']} DrugCentral uuid:60c5c5de-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:60c5eeb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00749 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Urokinase-type plasminogen activator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:60c61764-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:60c6428e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:60c66b74-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:60c69450-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:60c6bd36-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:60c6e676-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:60c70f52-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:60c738b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:60c76aec-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:60c76aec-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:60c76aec-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DP25 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Cytosolic other (Calmodulin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:60c7ab9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:60c7d46e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:60c7fe80-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.42']} DrugCentral uuid:60c828b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:60c85164-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.17']} DrugCentral uuid:60c87a5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.58']} DrugCentral uuid:60c8a376-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:60c8cc34-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:60c8f4fc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:60c91dce-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:60c94736-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:60c9708a-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:60c9995c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:60c9c238-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:60c9edf8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:60ca16b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:60ca3f88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:60ca69fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:60ca92ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:60cabbac-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:60cae460-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:60cb0e04-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:60cb36d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:60cb60a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:60cb8960-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:60cbb322-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:60cbdbf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05164 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Myeloperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:60cc04d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08253 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (72 kDa type IV collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:60cc2d8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:60cc56ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:60cc7f78-6b31-11ec-b3df-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:60cca82c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:60ccd0f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04760 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lactoylglutathione lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:60ccfa66-6b31-11ec-b3df-0242ac110002 UniProtKB:P04745 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Alpha-amylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:60cd232e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:60cd4bf6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:60cd74b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P16050 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:60cd9f16-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:60cdc7f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08254 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Stromelysin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.25']} DrugCentral uuid:60cdf09c-6b31-11ec-b3df-0242ac110002 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:60ce19d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:60ce42cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P37059 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Estradiol 17-beta-dehydrogenase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.81']} DrugCentral uuid:60ce6b94-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:60ce945c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48147 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Prolyl endopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:60cebdba-6b31-11ec-b3df-0242ac110002 UniProtKB:P18054 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 12-lipoxygenase, 12S-type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:60cee6b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:60cf0f7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:60cf3844-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:60cf6300-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:60cf8c4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:60cfb51c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:60cfddbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04054 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Phospholipase A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:60d006de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:60d02fb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:60d0586e-6b31-11ec-b3df-0242ac110002 UniProtKB:P39900 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Macrophage metalloelastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:60d08140-6b31-11ec-b3df-0242ac110002 UniProtKB:P45452 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Collagenase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:60d0aabc-6b31-11ec-b3df-0242ac110002 UniProtKB:P17538 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Chymotrypsinogen B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:60d0d37a-6b31-11ec-b3df-0242ac110002 UniProtKB:P56817 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-secretase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:60d0fc42-6b31-11ec-b3df-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:60d12744-6b31-11ec-b3df-0242ac110002 UniProtKB:P50578 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:60d15070-6b31-11ec-b3df-0242ac110002 UniProtKB:P80276 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:60d17938-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:60d1a1e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P06737 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Glycogen phosphorylase, liver form) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:60d1caf0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15046 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lysine--tRNA ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:60d1f426-6b31-11ec-b3df-0242ac110002 UniProtKB:P00760 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cationic trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:60d21ce4-6b31-11ec-b3df-0242ac110002 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:60d245d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:60d26f3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:60d297fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:60d2c0d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.22']} DrugCentral uuid:60d2e994-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:60d315ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P16116 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:60d33e9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:60d3678e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51635 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Alcohol dehydrogenase [NADP(+)]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:60d3918c-6b31-11ec-b3df-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:60d3ba72-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:60d3e34e-6b31-11ec-b3df-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:60d40c16-6b31-11ec-b3df-0242ac110002 UniProtKB:P21398 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:60d43588-6b31-11ec-b3df-0242ac110002 UniProtKB:P56560 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:60d45e50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:60d48718-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AEK4 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:60d4afd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q965D5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Enoyl-acyl-carrier protein reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:60d4da60-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:60d5065c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q91WR5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Aldo-keto reductase family 1 member C21) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:60d52fa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:60d55864-6b31-11ec-b3df-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:60d5819a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25024 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (C-X-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:60d5aa6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.93']} DrugCentral uuid:60d5d3b6-6b31-11ec-b3df-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:60d5fc7e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:60d625dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:60d64e90-6b31-11ec-b3df-0242ac110002 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:60d67744-6b31-11ec-b3df-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.86']} DrugCentral uuid:60d6a0f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC97 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets GPCR (G-protein coupled receptor 35) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.81']} DrugCentral uuid:60d6c9ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:60d6f28c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:60d71b2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10584 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Malate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:60d74444-6b31-11ec-b3df-0242ac110002 UniProtKB:P21588 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (5'-nucleotidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:60d76d0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q965D6 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (3-oxoacyl-acyl-carrier protein reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:60d796ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q965D7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-hydroxyacyl-ACP dehydratase; Fatty acid synthesis protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:60d7bf78-6b31-11ec-b3df-0242ac110002 UniProtKB:P27986 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Phosphatidylinositol 3-kinase regulatory subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.42']} DrugCentral uuid:60d7e8f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPH5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (NADPH oxidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:60d81306-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C6X7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:60d83bc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P80025 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lactoperoxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:60d86482-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:60d8902e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q1CTD3 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (D-alanine--D-alanine ligase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:60d8b914-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC98 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Serine/threonine-protein kinase Nek6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:60d8e1dc-6b31-11ec-b3df-0242ac110002 UniProtKB:O96394 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Arginase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:60d90e82-6b31-11ec-b3df-0242ac110002 UniProtKB:P14635 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:60d90e82-6b31-11ec-b3df-0242ac110002 UniProtKB:P14635 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:60d9479e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15078 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 5/CDK5 activator 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:60d9479e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15078 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 5/CDK5 activator 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.64']} DrugCentral uuid:60d987ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:60d987ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:60d987ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:60d987ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WWL7 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 1/cyclin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:60d9d93e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:60d9d93e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:60da11e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Glycogen synthase kinase-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:60da11e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Glycogen synthase kinase-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:60da468a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:60da702e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29477 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:60da9900-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00796 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Sorbitol dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.45']} DrugCentral uuid:60dac1b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99895 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Chymotrypsin C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:60daebd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03114 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Cell division protein kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.2']} DrugCentral uuid:60db14a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NWT6 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Hypoxia-inducible factor 1-alpha inhibitor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.99']} DrugCentral uuid:60db3d74-6b31-11ec-b3df-0242ac110002 UniProtKB:P07862 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (D-alanylalanine synthetase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:60db6646-6b31-11ec-b3df-0242ac110002 UniProtKB:P28907 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Tumour-associated antigen (Lymphocyte differentiation antigen CD38) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:60db8fb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01062 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Phosphodiesterase 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.09']} DrugCentral uuid:60dbb876-6b31-11ec-b3df-0242ac110002 UniProtKB:P28839 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cytosol aminopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:60dbe134-6b31-11ec-b3df-0242ac110002 UniProtKB:P41921 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Glutathione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.31']} DrugCentral uuid:60dc0a74-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:60dc35d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P04798 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Cytochrome P450 1A1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:60dc61fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P11168 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (Solute carrier family 2, facilitated glucose transporter member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:60dc8d00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14576 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Unclassified (ELAV-like protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:60dcb5c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15717 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Unclassified (ELAV-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:60dcdeea-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:60dd07d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:60dd30ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P19357 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Transporter (Solute carrier family 2, facilitated glucose transporter member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:60dd5a32-6b31-11ec-b3df-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:60dd8322-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFU5 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Inositol polyphosphate multikinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:60ddabf4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHH9 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Kinase (Inositol hexakisphosphate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:60ddd4d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL62 biolink:molecularly_interacts_with DrugCentral:3514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quercetin targets Ion channel (Short transient receptor potential channel 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.19']} DrugCentral uuid:60de0f22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:60de0f22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:60de0f22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:60de0f22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:60de0f22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07001 biolink:molecularly_interacts_with DrugCentral:3520 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rapacuronium is antagonist of Ion channel (Muscle-type nicotinic acetylcholine receptor) DrugCentral uuid:60de5eb4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:60de87ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:60deb1fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:60dedace-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:60df03be-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.36']} DrugCentral uuid:60df2d30-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:3521 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rasagiline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:60df560c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:60df7ed4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.16']} DrugCentral uuid:60dfa7ba-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:60dfd208-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:60dffb3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.15']} DrugCentral uuid:60e0241a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:60e04cf6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:60e07622-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.06']} DrugCentral uuid:60e09f08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:3524 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 resorcinol targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.19']} DrugCentral uuid:60e0cbd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revaprazan is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:60e0cbd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3525 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revaprazan is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:60e0fade-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:3529 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rioprostil is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) DrugCentral uuid:60e120ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:60e149da-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.46']} DrugCentral uuid:60e17298-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.57']} DrugCentral uuid:60e1a894-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:60e1a894-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:60e1a894-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:60e1a894-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:60e1f5c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WQX9 biolink:molecularly_interacts_with DrugCentral:3531 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roflumilast targets Enzyme (Phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.5']} DrugCentral uuid:60e21e82-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:60e247b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:60e27184-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:60e29a56-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:60e2c328-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:60e2eca4-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:60e31576-6b31-11ec-b3df-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:60e33e48-6b31-11ec-b3df-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:60e3671a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:60e3926c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:60e3bb3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:60e3e410-6b31-11ec-b3df-0242ac110002 UniProtKB:P05771 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C beta type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.33']} DrugCentral uuid:60e40d1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:60e43730-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:60e46034-6b31-11ec-b3df-0242ac110002 UniProtKB:P22694 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:60e488fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:60e4b25a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:60e4db22-6b31-11ec-b3df-0242ac110002 UniProtKB:P05129 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C gamma type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:60e503ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:60e52cc6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:60e55796-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:60e58374-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:60e5af48-6b31-11ec-b3df-0242ac110002 UniProtKB:P24723 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C eta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:60e5d9d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:60e6031c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:60e62c02-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:60e65600-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:60e67f7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:60e6a858-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:60e6d13e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:60e6fa2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:60e7245e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.6']} DrugCentral uuid:60e74fb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:60e77918-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:60e7a1f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P1W9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase pim-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:60e7cb48-6b31-11ec-b3df-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:60e7f41a-6b31-11ec-b3df-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:60e81cf6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:60e845d2-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:60e86f12-6b31-11ec-b3df-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:60e897ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:60e8c0c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:60e8e99c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:60e9149e-6b31-11ec-b3df-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:60e93d52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:60e96624-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:60e98fa0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:60e9b87c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:60e9e144-6b31-11ec-b3df-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:60ea0a0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JI10 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:60ea3360-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:60ea5d4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:60ea8608-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:60eaaee4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31751 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (RAC-beta serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:60ead9f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:60eb0484-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:60eb2d92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:60eb566e-6b31-11ec-b3df-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:60eb7ff4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:60eba8c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:60ebd1a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:60ebfa88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:60ec23c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:60ec4cae-6b31-11ec-b3df-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:60ec758a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:60ec9fce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:60ecc990-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:60ecf26c-6b31-11ec-b3df-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:60ed1b48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:60ed44d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:60ed6dbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:60ed96a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:60edbf8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y243 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (RAC-gamma serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:60ede8de-6b31-11ec-b3df-0242ac110002 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:60ee123c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:60ee3b04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:60ee64e4-6b31-11ec-b3df-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:60ee8fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:60eeb8ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:60eee194-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:60ef0b24-6b31-11ec-b3df-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:60ef33f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:60ef5cbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:60ef859a-6b31-11ec-b3df-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:60efaebc-6b31-11ec-b3df-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:60efd78e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:60f00060-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:60f02932-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:60f052cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:60f07c20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:60f0a4f2-6b31-11ec-b3df-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:60f0cdc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:60f0f736-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:60f12030-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:60f148f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:60f171c0-6b31-11ec-b3df-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:60f19af6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:60f1c3c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:60f1edd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:60f21756-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:60f241d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:60f26aa8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.11']} DrugCentral uuid:60f2938e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:60f2bd0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:60f2e5e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:60f30ecc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:60f337a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:60f360e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:60f389ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:60f3b296-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:60f3db72-6b31-11ec-b3df-0242ac110002 UniProtKB:O76039 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Cyclin-dependent kinase-like 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:60f4070a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41743 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C iota type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:60f42fdc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:60f458b8-6b31-11ec-b3df-0242ac110002 UniProtKB:O60331 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:60f4818a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:60f4ab4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:60f4d428-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:60f4fd04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:60f540ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:60f540ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:60f540ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:60f540ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:60f540ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:60f540ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:60f540ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:60f540ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WTQ0 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (Protein kinase C (PKC)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:60f5cad6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:60f5cad6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:60f5cad6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:60f5cad6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:3533 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruboxistaurin targets Kinase (CaM kinase II) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:60f61798-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:60f66306-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:60f66306-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:60f66306-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:60f66306-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:60f66306-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:60f66306-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:60f66306-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:60f66306-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:60f66306-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:60f66306-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:60f6e61e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:3534 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rufinamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.46']} DrugCentral uuid:60f70f68-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:60f7384e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.454']} DrugCentral uuid:60f7612a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:60f789fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:60f7b4ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:60f7ddb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:60f8067a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.89']} DrugCentral uuid:60f82f56-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.16']} DrugCentral uuid:60f8586e-6b31-11ec-b3df-0242ac110002 UniProtKB:P02769 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Secreted (Serum albumin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:60f88136-6b31-11ec-b3df-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.47']} DrugCentral uuid:60f8a9ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.51']} DrugCentral uuid:60f8d424-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:60f8fce2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZQ4 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets GPCR (Neuromedin-U receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:60f92582-6b31-11ec-b3df-0242ac110002 UniProtKB:P03469 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:60f94e40-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:3535 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rutoside targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.67']} DrugCentral uuid:60f9791a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:60f9a1e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:60f9cac8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:60f9f39a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.24']} DrugCentral uuid:60fa1cf8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline is agonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:60fa54fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:60fa54fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:60fa54fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:60fa54fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:60fa54fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sabcomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:60faae0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:60fad6f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin targets GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:60faffd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:60fb28a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35351 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin is antagonist of GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:60fb562c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:60fb562c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3542 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saralasin targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:60fb8b9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:3548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitaxentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:60fbb4aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:3548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitaxentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:60fbddea-6b31-11ec-b3df-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:3548 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sitaxentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:60fc06c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:3553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stallimycin targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:60fc2fa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P01112 biolink:molecularly_interacts_with DrugCentral:3553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stallimycin targets Cytosolic other (GTPase HRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:60fc5d42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stallimycin targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:60fc5d42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:3553 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stallimycin targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:60fc929e-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:3557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbentine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:60fcbb5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:3557 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulbentine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:60fce438-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:3574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulmazole targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:60fd1214-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:3574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulmazole targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:60fd1214-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:3574 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulmazole targets Enzyme (Phosphodiesterase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:60fd47de-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxedrine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.2']} DrugCentral uuid:60fd70b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZQ4 biolink:molecularly_interacts_with DrugCentral:3577 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxedrine targets GPCR (Neuromedin-U receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:60fd9978-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3579 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talastine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:60fdbe76-6b31-11ec-b3df-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:3580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamibarotene targets Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:60fde766-6b31-11ec-b3df-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:3580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamibarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:60fe1038-6b31-11ec-b3df-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:3580 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tamibarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:60fe38ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:60fe622c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:60fe8ad6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:60feb3c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.95']} DrugCentral uuid:60fedca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:60ff090c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:60ff33be-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:60ff5c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:60ff85da-6b31-11ec-b3df-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) DrugCentral uuid:60ffaa60-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.63']} DrugCentral uuid:60ffd3aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:60fffc9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.09']} DrugCentral uuid:610025d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.11']} DrugCentral uuid:61004fa6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:61007878-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.59']} DrugCentral uuid:6100a15e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:3584 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 terazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.16']} DrugCentral uuid:6100d35e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:6100d35e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:6100d35e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:61011bf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61011bf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61011bf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61016fd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:61016fd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:61016fd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:61016fd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:61016fd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:61016fd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:6101e80c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:6101e80c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:6101e80c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:6101e80c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:6101e80c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:6101e80c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3591 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetryzoline is agonist of GPCR (Adrenergic receptor alpha) DrugCentral uuid:61024220-6b31-11ec-b3df-0242ac110002 UniProtKB:O00519 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:61026ae8-6b31-11ec-b3df-0242ac110002 UniProtKB:O75936 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Gamma-butyrobetaine dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:61029522-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99685 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Monoglyceride lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.01']} DrugCentral uuid:6102bfa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WMN3 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Bifunctional protein GlmU) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:6102e874-6b31-11ec-b3df-0242ac110002 UniProtKB:P28300 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Protein-lysine 6-oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:61031164-6b31-11ec-b3df-0242ac110002 UniProtKB:P58215 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Lysyl oxidase homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:61033cf2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96JB6 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Lysyl oxidase homolog 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:61036920-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96KQ7 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Histone-lysine N-methyltransferase EHMT2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.26']} DrugCentral uuid:61039242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H9B1 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Histone-lysine N-methyltransferase EHMT1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:6103bb28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K0 biolink:molecularly_interacts_with DrugCentral:3601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiram targets Enzyme (Lysyl oxidase homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:6103e472-6b31-11ec-b3df-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:3604 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thyropropic acid targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.39']} DrugCentral uuid:61040d30-6b31-11ec-b3df-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:3604 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thyropropic acid targets Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.72']} DrugCentral uuid:61043616-6b31-11ec-b3df-0242ac110002 UniProtKB:P12004 biolink:molecularly_interacts_with DrugCentral:3604 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thyropropic acid targets Nuclear other (Proliferating cell nuclear antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:61045ef2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioxolone targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:61048b70-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:3607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioxolone targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:6104b55a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3607 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tioxolone targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:6104de18-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:61050302-6b31-11ec-b3df-0242ac110002 UniProtKB:P07339 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Enzyme (Cathepsin D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:61052bfc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:610554c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q80W54 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Enzyme (CAAX prenyl protease 1 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:61057d8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14091 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Enzyme (Cathepsin E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.05']} DrugCentral uuid:6105a6c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DJD9 biolink:molecularly_interacts_with DrugCentral:3609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipranavir targets Enzyme (Pepsin A-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:6105cf94-6b31-11ec-b3df-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.85']} DrugCentral uuid:6105f85c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10828 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Nuclear hormone receptor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.39']} DrugCentral uuid:61062142-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:61064bc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18113 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Transcription factor (Thyroid hormone receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.82']} DrugCentral uuid:6106748a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12004 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Nuclear other (Proliferating cell nuclear antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:61069d5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:6106c6d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:3611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tiratricol targets Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:6106eff0-6b31-11ec-b3df-0242ac110002 UniProtKB:P09211 biolink:molecularly_interacts_with DrugCentral:3613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Vitamin E targets Enzyme (Glutathione S-transferase P) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:610718b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P49638 biolink:molecularly_interacts_with DrugCentral:3613 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Vitamin E targets Transporter (Alpha-tocopherol transfer protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:61074284-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:3616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toliprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.42']} DrugCentral uuid:61076b4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:3616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toliprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.92']} DrugCentral uuid:61079496-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28044 biolink:molecularly_interacts_with DrugCentral:3616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toliprolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.36']} DrugCentral uuid:6107bd86-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:3616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 toliprolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.75']} DrugCentral uuid:6107e64e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3617 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolnaftate targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.894']} DrugCentral uuid:61081024-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:3617 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolnaftate targets Enzyme (Cytochrome P450 2C19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:610839be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16850 biolink:molecularly_interacts_with DrugCentral:3617 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolnaftate targets Enzyme (Lanosterol 14-alpha demethylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:61086290-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:61088b6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.86']} DrugCentral uuid:6108b4a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.56']} DrugCentral uuid:6108e51c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:6108e51c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:6108e51c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:61092f22-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:61092f22-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:61092f22-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3620 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tramazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:61097054-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:3630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclocarban targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:6109993a-6b31-11ec-b3df-0242ac110002 UniProtKB:P95276 biolink:molecularly_interacts_with DrugCentral:3630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclocarban targets Enzyme (Epoxide hydrolase; Epoxide hydrolase EphB) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:6109c1ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P07099 biolink:molecularly_interacts_with DrugCentral:3630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclocarban targets Enzyme (Epoxide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:6109ec82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D379 biolink:molecularly_interacts_with DrugCentral:3630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclocarban targets Enzyme (Epoxide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:610a18ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WGR1 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:610a42ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P16152 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Carbonyl reductase [NADPH] 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.22']} DrugCentral uuid:610a6ba8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6GI75 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:610a94e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AEK4 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan is inhibitor of Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:610abdba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q965D5 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-acyl-carrier protein reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.28']} DrugCentral uuid:610ae772-6b31-11ec-b3df-0242ac110002 UniProtKB:P54616 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH] FabI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:610b1062-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6UCJ9 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-acyl carrier reductase; Enoyl-acyl carrier reductase ENR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:610b398e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BJJ9 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-ACP reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:610b6274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9RMI3 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADPH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:610b8b50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5NGQ3 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NADH]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:610bb42c-6b31-11ec-b3df-0242ac110002 UniProtKB:M9TGV3 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Enzyme (Enoyl-[acyl-carrier-protein] reductase [NULLDH]) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.7']} DrugCentral uuid:610bdeac-6b31-11ec-b3df-0242ac110002 UniProtKB:P11021 biolink:molecularly_interacts_with DrugCentral:3631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triclosan targets Unclassified (78 kDa glucose-regulated protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:610c079c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51582 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:610c3064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15077 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:610c597c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:610c82bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96G91 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:610cab8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P56373 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate targets Ion channel (P2X purinoceptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.583']} DrugCentral uuid:610cd474-6b31-11ec-b3df-0242ac110002 UniProtKB:O35811 biolink:molecularly_interacts_with DrugCentral:3639 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 uridine triphosphate is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:610cfd8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:610d2668-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.09']} DrugCentral uuid:610d4f3a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.17']} DrugCentral uuid:610d782a-6b31-11ec-b3df-0242ac110002 UniProtKB:P97321 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:610da264-6b31-11ec-b3df-0242ac110002 UniProtKB:E1BI31 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Unclassified (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:610dcb36-6b31-11ec-b3df-0242ac110002 UniProtKB:O31048 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin targets Unclassified (Dipeptidyl peptidase IV) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:610df41c-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:3642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vildagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:610e1d0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:610e464c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:610e6f14-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:610e97f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3643 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vincamine is allosteric modulator of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.2']} DrugCentral uuid:610edfd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:610edfd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:610edfd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:610edfd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:610edfd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:610edfd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:610edfd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:610edfd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:610edfd0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:3644 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vinflunine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:610f5a82-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3651 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorozole is inhibitor of Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.86']} DrugCentral uuid:610f849e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:610fad84-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:610fd656-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:610fff82-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:6110287c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:61105162-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:61107a48-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.9']} DrugCentral uuid:6110a388-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:6110cc6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:6110f55e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.92']} DrugCentral uuid:61111e3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:61114874-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:61117150-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:61119a2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:6111c312-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:6111ec52-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61121538-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:61123e0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:611267f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:6112912a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:6112ba06-6b31-11ec-b3df-0242ac110002 UniProtKB:P12657 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:6112f28c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:6112f28c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:6112f28c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:6112f28c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:6112f28c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:3652 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xanomeline targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.01']} DrugCentral uuid:6113518c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.82']} DrugCentral uuid:61137a68-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.04']} DrugCentral uuid:6113a326-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:6113cc70-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:6113f538-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:611425bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:611425bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:611425bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:61146ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:61146ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:61146ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:6114c24c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:6114c24c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:6114c24c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:6114c24c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:6114c24c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:6114c24c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline targets GPCR (Adrenergic receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.32']} DrugCentral uuid:61152ae8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3658 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 xylometazoline is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:611553ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.163']} DrugCentral uuid:61157d0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:6115a5f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:6115cebc-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:6115f7ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.106']} DrugCentral uuid:6116210a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:611649dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:611672e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:61169bb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:6116c592-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:6116ee64-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:61171768-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:61174044-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.692']} DrugCentral uuid:61176984-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.02']} DrugCentral uuid:61179260-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:6117bb1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:6117e404-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.3']} DrugCentral uuid:61180d26-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:6118362a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:61185efc-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:611887c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.182']} DrugCentral uuid:6118b49c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.91']} DrugCentral uuid:6118e08e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19328 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:61190c80-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.28']} DrugCentral uuid:6119373c-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.95']} DrugCentral uuid:61195ffa-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:611988ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:6119b18a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:6119db4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22002 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:611a043c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.44']} DrugCentral uuid:611a2d18-6b31-11ec-b3df-0242ac110002 UniProtKB:P18871 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:611a55f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.61']} DrugCentral uuid:611a81fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:611ab26a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:611ab26a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:611ab26a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:611b03fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:611b03fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:611b03fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:611b03fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:611b03fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:611b643a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:611b643a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:611b643a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:611bace2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:611bace2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:611bace2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:611bed9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30304 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine targets Enzyme (Dual specificity phosphatase Cdc25A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.65']} DrugCentral uuid:611c166e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28334 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:611c40f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30966 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:611c69e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:3659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 yohimbine is antagonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:611c92c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacyclonol targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:611cc35c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacyclonol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:611cc35c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacyclonol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:611cc35c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3680 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azacyclonol targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:611d048e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:3686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.67']} DrugCentral uuid:611d2d7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:3686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.93']} DrugCentral uuid:611d5646-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:3686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:611d7fcc-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:3686 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzylsulfamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:611da89e-6b31-11ec-b3df-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:3689 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bropirimine targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:611dd17a-6b31-11ec-b3df-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:3707 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chlorthenoxazine targets Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:611dfa56-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:3713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ciramadol is modulator of GPCR (Mu-type opioid receptor) DrugCentral uuid:611e2148-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:3715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobenztropine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:611e5460-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diperodon targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:611e5460-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diperodon targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:611e5460-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3734 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diperodon targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:611e9cc2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprylcaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:611e9cc2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprylcaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:611e9cc2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3770 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meprylcaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:611eddb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3787 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 myrtecaine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.316']} DrugCentral uuid:611f0e50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parethoxycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:611f0e50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parethoxycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:611f0e50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:3805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parethoxycaine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:611f543c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:611f543c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:3839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasosartan targets GPCR (Angiotensin II receptor (AT-1) type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:611f892a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:3839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasosartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:611fb288-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:611fdb3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:612004ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:61202ef2-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:612057e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9N1N9 biolink:molecularly_interacts_with DrugCentral:3848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velnacrine targets Enzyme (Butyrylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.27']} DrugCentral uuid:6120817c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:6120aa44-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.01']} DrugCentral uuid:6120d334-6b31-11ec-b3df-0242ac110002 UniProtKB:P52895 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Aldo-keto reductase family 1 member C2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.37']} DrugCentral uuid:6120fc1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42330 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Aldo-keto reductase family 1 member C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:6121253c-6b31-11ec-b3df-0242ac110002 UniProtKB:P05979 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:61214dfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:3851 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexibuprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:612176cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:3855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:61219fbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:3855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:6121cb40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:3855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 docosanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:6121f66a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:61221f3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:61224822-6b31-11ec-b3df-0242ac110002 UniProtKB:P28702 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:612271bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P48443 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.66']} DrugCentral uuid:61229a8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:6122c360-6b31-11ec-b3df-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.13']} DrugCentral uuid:6122ecaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P51449 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear hormone receptor (Nuclear receptor ROR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:6123166c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28704 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor RXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:61233f34-6b31-11ec-b3df-0242ac110002 UniProtKB:P28705 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor RXR-gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:6123681a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11416 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:612391e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28700 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:6123bae0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22605 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:6123e3c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18911 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Transcription factor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:61240ca2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05343 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:6124360a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22736 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear other (Nuclear receptor subfamily 4 group A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:61245ef0-6b31-11ec-b3df-0242ac110002 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:612487b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13133 biolink:molecularly_interacts_with DrugCentral:3862 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alitretinoin targets Nuclear other (Oxysterols receptor LXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:6124b062-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:3871 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 artemisinin targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:6124da4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.41']} DrugCentral uuid:6125031e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:61252be6-6b31-11ec-b3df-0242ac110002 UniProtKB:O43193 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets GPCR (Motilin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:612554a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:61257e34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:3875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzamycin targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.01']} DrugCentral uuid:6125a71a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95180 biolink:molecularly_interacts_with DrugCentral:3880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benidipine is blocker of Ion channel (Voltage-dependent T-type calcium channel subunit alpha-1H) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.843']} DrugCentral uuid:6125d3d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:3880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:6125d3d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:3880 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:612614ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:612614ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:612614ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:612614ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:3881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzydamine targets Enzyme (Soluble guanylate cyclase) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:61266164-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biriperone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:61268b62-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biriperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.88']} DrugCentral uuid:6126b592-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:3883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biriperone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:6126de6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:3883 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 biriperone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:6127074a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3911 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasone butyrate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:61272be4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:61275862-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:612783aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.665']} DrugCentral uuid:6127ac68-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.372']} DrugCentral uuid:6127d5f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:6127feb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:61282792-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.307']} DrugCentral uuid:6128506e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:612879ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.11']} DrugCentral uuid:6128a294-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:6128cb70-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:6128f44c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:61291e18-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:6129471c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:61297002-6b31-11ec-b3df-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.25']} DrugCentral uuid:6129a8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:6129a8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:6129a8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:6129a8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:6129a8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:612a08f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:612a08f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:612a08f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:612a529c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:612a529c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:612a529c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:612a934c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPC2 biolink:molecularly_interacts_with DrugCentral:3912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clorotepine targets Ion channel (Potassium channel subfamily K member 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.13']} DrugCentral uuid:612abc32-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:612ae680-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:612b0fde-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:612b38e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:612b61d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.79']} DrugCentral uuid:612b8b80-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:612bb452-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.52']} DrugCentral uuid:612bdd4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:3920 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexamethasone phosphate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:612c0628-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:612c2f5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:612c581c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:612c8116-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:612cab14-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:612cd5ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:612cfeac-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.74']} DrugCentral uuid:612d279c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.57']} DrugCentral uuid:612d5122-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.788']} DrugCentral uuid:612d7a12-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:612da33e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19091 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:612dcc1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06186 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:612df62c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22199 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Transcription factor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:612e1f08-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:3927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 androstanolone targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:612e47d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:3931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolasetron targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.226']} DrugCentral uuid:612e70ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:3931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolasetron is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.698']} DrugCentral uuid:612e9a5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:3944 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etoposide phosphate is inhibitor of Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:612ebef4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz is agonist of GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:612ee7e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.928']} DrugCentral uuid:612f10ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.951']} DrugCentral uuid:612f3a3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.208']} DrugCentral uuid:612f6318-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.971']} DrugCentral uuid:612f8c12-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz is agonist of GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.167']} DrugCentral uuid:612fb548-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz is agonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.793']} DrugCentral uuid:612fde9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.801']} DrugCentral uuid:61300778-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.748']} DrugCentral uuid:6130304a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:61305a02-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.46']} DrugCentral uuid:613083c4-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.31']} DrugCentral uuid:6130ac8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.122']} DrugCentral uuid:6130d568-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:6130feb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:61312f22-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:61312f22-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:61312f22-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:3952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guanabenz targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:61316fd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:3959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone butyrate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:613198ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ilaprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:613198ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:3961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ilaprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:6131c8ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.646']} DrugCentral uuid:6131f1aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.66']} DrugCentral uuid:61321a68-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:61324592-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.407']} DrugCentral uuid:61326e96-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.125']} DrugCentral uuid:6132977c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.924']} DrugCentral uuid:6132c04e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.891']} DrugCentral uuid:6132e9c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.586']} DrugCentral uuid:613313c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.244']} DrugCentral uuid:61333ca4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.451']} DrugCentral uuid:613365e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.539']} DrugCentral uuid:61338eca-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is allosteric modulator of Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:6133b792-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:6133ebcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:6133ebcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:6133ebcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:6133ebcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P48167 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is agonist of Ion channel (Glycine Receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:61343a6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P91730 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is modulator of Ion channel (Glutamate-gated chloride channel) DrugCentral uuid:61345efe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q25634 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is modulator of Ion channel (Glutamate-gated chloride channel) DrugCentral uuid:61348370-6b31-11ec-b3df-0242ac110002 UniProtKB:P11507 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Enzyme (Sarcoplasmic/endoplasmic reticulum calcium ATPase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:6134acce-6b31-11ec-b3df-0242ac110002 UniProtKB:P06685 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Enzyme (Sodium/potassium-transporting ATPase subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:6134d58c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q64578 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin targets Enzyme (Sarcoplasmic/endoplasmic reticulum calcium ATPase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:6134fe7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51577 biolink:molecularly_interacts_with DrugCentral:3972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivermectin is allosteric modulator of Unclassified (P2X purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:6135273a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29029 biolink:molecularly_interacts_with DrugCentral:3976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kinetin targets Enzyme (Endochitinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:6135505c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:61357a1e-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.65']} DrugCentral uuid:6135a304-6b31-11ec-b3df-0242ac110002 UniProtKB:P14920 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:6135cbe0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00371 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Unclassified (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.68']} DrugCentral uuid:6135f728-6b31-11ec-b3df-0242ac110002 UniProtKB:P11344 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.21']} DrugCentral uuid:61362018-6b31-11ec-b3df-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:613648cc-6b31-11ec-b3df-0242ac110002 UniProtKB:B2ZB02 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Unclassified (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:61367356-6b31-11ec-b3df-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Unclassified (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.91']} DrugCentral uuid:61369c8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00024 biolink:molecularly_interacts_with DrugCentral:3977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 kojic acid targets Enzyme (Polyphenol oxidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:6136c572-6b31-11ec-b3df-0242ac110002 UniProtKB:O75936 biolink:molecularly_interacts_with DrugCentral:3995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 meldonium targets Enzyme (Gamma-butyrobetaine dioxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:6136ee4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NQS5 biolink:molecularly_interacts_with DrugCentral:3998 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octanoic acid targets GPCR (G-protein coupled receptor 84) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:61371798-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NQS5 biolink:molecularly_interacts_with DrugCentral:3998 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 octanoic acid targets GPCR (G-protein coupled receptor 84) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.71']} DrugCentral uuid:6137407e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4002 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niperotidine is antagonist of GPCR (Histamine H2 receptor) DrugCentral uuid:61376522-6b31-11ec-b3df-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.71']} DrugCentral uuid:61378df4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47901 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan is antagonist of GPCR (Vasopressin V1b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.8']} DrugCentral uuid:6137b86a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30559 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Oxytocin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.18']} DrugCentral uuid:6137e3da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:61380cac-6b31-11ec-b3df-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:61383948-6b31-11ec-b3df-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:61383948-6b31-11ec-b3df-0242ac110002 UniProtKB:P48974 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan targets GPCR (Vasopressin V1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:61386f12-6b31-11ec-b3df-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:4004 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mozavaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.03']} DrugCentral uuid:613897f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.04']} DrugCentral uuid:6138c0de-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:6138ea00-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:613912b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.74']} DrugCentral uuid:61393b4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oxitriptan targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.67']} DrugCentral uuid:6139646c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14832 biolink:molecularly_interacts_with DrugCentral:4050 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spaglumic acid is agonist of GPCR (Metabotropic glutamate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:61399126-6b31-11ec-b3df-0242ac110002 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.84']} DrugCentral uuid:6139b9f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P48147 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Enzyme (Prolyl endopeptidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:6139e2b6-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613a44f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UN88 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:613b20fe-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4055 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baicalin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:613b49d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:613b7568-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:613b9e3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.81']} DrugCentral uuid:613bc716-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:613befe8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:613c1a86-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.78']} DrugCentral uuid:613c436c-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:4061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 timolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.44']} DrugCentral uuid:613c6c52-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.807']} DrugCentral uuid:613c95a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.243']} DrugCentral uuid:613cbf22-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.929']} DrugCentral uuid:613ce876-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.425']} DrugCentral uuid:613d1152-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.857']} DrugCentral uuid:613d3c22-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:613d64fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.69']} DrugCentral uuid:613d8dc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.802']} DrugCentral uuid:613db684-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.952']} DrugCentral uuid:613de00a-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.789']} DrugCentral uuid:613e08dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:4063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirilazad targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:613e31ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:613e5a62-6b31-11ec-b3df-0242ac110002 UniProtKB:P13674 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Enzyme (Prolyl 4-hydroxylase subunit alpha-1) DrugCentral uuid:613e7f4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02809 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Enzyme (Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1) DrugCentral uuid:613ea3be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UGH3 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Transporter (Solute carrier family 23 member 2) DrugCentral uuid:613ec966-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHI7 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Transporter (Solute carrier family 23 member 1) DrugCentral uuid:613eede2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00689 biolink:molecularly_interacts_with DrugCentral:4072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ascorbic acid targets Enzyme (Pancreatic alpha-amylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:613f1998-6b31-11ec-b3df-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:4074 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minodronic acid targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:613f44c2-6b31-11ec-b3df-0242ac110002 UniProtKB:O95749 biolink:molecularly_interacts_with DrugCentral:4074 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minodronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:613f6d94-6b31-11ec-b3df-0242ac110002 UniProtKB:P22939 biolink:molecularly_interacts_with DrugCentral:4074 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minodronic acid targets Enzyme (Farnesyl diphosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:613f965c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12051 biolink:molecularly_interacts_with DrugCentral:4074 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 minodronic acid targets Enzyme (Geranylgeranyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:613fc3e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamlodipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:613fc3e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4099 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levamlodipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:613ff2e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DJD9 biolink:molecularly_interacts_with DrugCentral:4106 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sucralfate is inhibitor of Enzyme (Pepsin A-5) DrugCentral uuid:61401762-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is agonist of GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:61404174-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.99']} DrugCentral uuid:61406a28-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:614092fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P23416 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is allosteric modulator of Ion channel (Glycine receptor subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:6140bbae-6b31-11ec-b3df-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:6140e692-6b31-11ec-b3df-0242ac110002 UniProtKB:O75311 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is allosteric modulator of Ion channel (Glycine receptor subunit alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:6141125c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14330 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (N-arachidonyl glycine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:61413d9a-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:61416662-6b31-11ec-b3df-0242ac110002 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.43']} DrugCentral uuid:61418fde-6b31-11ec-b3df-0242ac110002 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.04']} DrugCentral uuid:6141b8b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47746 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.4']} DrugCentral uuid:6141e1a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:61420ec8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:61420ec8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:61424780-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QZN9 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:61424780-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QZN9 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol targets GPCR (Cannabinoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:61427c64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WUD2 biolink:molecularly_interacts_with DrugCentral:4109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronabinol is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:6142a518-6b31-11ec-b3df-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:4110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.9']} DrugCentral uuid:6142cf34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00788 biolink:molecularly_interacts_with DrugCentral:4110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:6142f7fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30560 biolink:molecularly_interacts_with DrugCentral:4110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V1a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:6143216e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30518 biolink:molecularly_interacts_with DrugCentral:4110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tolvaptan is antagonist of GPCR (Vasopressin V2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:61434ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:4111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 besifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:61434ebe-6b31-11ec-b3df-0242ac110002 UniProtKB:P20083 biolink:molecularly_interacts_with DrugCentral:4111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 besifloxacin is inhibitor of Enzyme (Topoisomerase IV) DrugCentral uuid:61438190-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:4111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 besifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:61438190-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AES6 biolink:molecularly_interacts_with DrugCentral:4111 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 besifloxacin is inhibitor of Enzyme (DNA gyrase) DrugCentral uuid:6143b066-6b31-11ec-b3df-0242ac110002 UniProtKB:P10827 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Nuclear hormone receptor (Thyroid hormone receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.229']} DrugCentral uuid:6143d942-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:6144035e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06432 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Ion channel (Voltage-dependent calcium channel gamma-1 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:61442c30-6b31-11ec-b3df-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:61445502-6b31-11ec-b3df-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:61447f0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NVV9 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone targets Unclassified (THAP domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.229']} DrugCentral uuid:6144a91c-6b31-11ec-b3df-0242ac110002 UniProtKB:O60741 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1) DrugCentral uuid:6144cdde-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL51 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2) DrugCentral uuid:6144f278-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P1Z3 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3) DrugCentral uuid:614518a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3Q4 biolink:molecularly_interacts_with DrugCentral:4112 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dronedarone is blocker of Ion channel (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) DrugCentral uuid:61453d3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:4113 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prasugrel is antagonist of GPCR (P2Y purinoceptor 12) DrugCentral uuid:614561b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin targets Enzyme (Cytochrome P450 3A4) DrugCentral uuid:61458620-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:6145aac4-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:6145d3f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:6145fce0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4114 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saxagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:614625a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:61464e84-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:614678c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:6146a1ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.75']} DrugCentral uuid:6146ca6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.187']} DrugCentral uuid:6146f3b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.97']} DrugCentral uuid:61471c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.61']} DrugCentral uuid:61474564-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:61476e22-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.93']} DrugCentral uuid:6147974e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:6147c02a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.47']} DrugCentral uuid:6147e906-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:614812be-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.73']} DrugCentral uuid:61483d5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:61486638-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.644']} DrugCentral uuid:61488f00-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:6148b7d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:6148e108-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.107']} DrugCentral uuid:614909d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.039']} DrugCentral uuid:614932ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.491']} DrugCentral uuid:61495b74-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.565']} DrugCentral uuid:614984c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:6149ada4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.4']} DrugCentral uuid:6149d66c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:614a0074-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.504']} DrugCentral uuid:614a2946-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.71']} DrugCentral uuid:614a520e-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.349']} DrugCentral uuid:614a7b62-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.409']} DrugCentral uuid:614aa498-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:614acd56-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:4115 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asenapine is agonist of GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:614af65a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralatrexate is inhibitor of Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.35']} DrugCentral uuid:614b1f4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NT5 biolink:molecularly_interacts_with DrugCentral:4117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralatrexate targets Transporter (Proton-coupled folate transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:614b4880-6b31-11ec-b3df-0242ac110002 UniProtKB:P41440 biolink:molecularly_interacts_with DrugCentral:4117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralatrexate targets Transporter (Folate transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.16']} DrugCentral uuid:614b715c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15328 biolink:molecularly_interacts_with DrugCentral:4117 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralatrexate targets Membrane receptor (Folate receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:614b9a2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:614bc42c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:614bf096-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:614c1b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:614c4442-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.74']} DrugCentral uuid:614c6d96-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:614c9672-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:614cbf58-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:614ce848-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:614d1174-6b31-11ec-b3df-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:614d3a46-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:614d6318-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:614d8bf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:614db6ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:614ddf96-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:614e087c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:614e316c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.1']} DrugCentral uuid:614e5ac0-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.31']} DrugCentral uuid:614e839c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:614eac6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:614ed55e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:614efec6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:614f27a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:614f507e-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:614f7a72-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:614fa45c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:614fcd42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:614ff614-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:61502044-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:6150490c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:61507256-6b31-11ec-b3df-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:61509b28-6b31-11ec-b3df-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:6150c472-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:6150ed3a-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:615115f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:61513eca-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:615169f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:615192da-6b31-11ec-b3df-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:6151bba2-6b31-11ec-b3df-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:6151e47e-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:6152105c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:61523942-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:61526200-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61528b68-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:6152b566-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:6152de2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:615306ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:615331bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:61535ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:615383b0-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:6153ac8c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:6153d5c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:6153fe9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:61542874-6b31-11ec-b3df-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:61545146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:61547a72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:6154a34e-6b31-11ec-b3df-0242ac110002 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:6154cc3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib is inhibitor of Kinase (Tyrosine-protein kinase ITK/TSK) DrugCentral uuid:6154f0ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:61551ab8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:6155439e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:61556c84-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:615595d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:6155bea0-6b31-11ec-b3df-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:6155e790-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:61561058-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:6156397a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:61566256-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13705 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Activin receptor type-2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:61568b32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:6156b3f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:6156de48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:61570706-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61572fec-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:61575940-6b31-11ec-b3df-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:61578302-6b31-11ec-b3df-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:6157abde-6b31-11ec-b3df-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:6157d49c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:6157fd6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21127 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Cyclin-dependent kinase 11B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:6158285c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ88 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Cyclin-dependent kinase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:61585142-6b31-11ec-b3df-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:61587a28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:6158a46c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:6158cd70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6P3R8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase Nek5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:6158f642-6b31-11ec-b3df-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:61591f14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:615948ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:615972f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:61599bd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:6159c4a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:6159ede0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:615a16bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:615a3f98-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:615a6874-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:615a933a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:615abc20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:615ae4de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:615b0dc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:615b370e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:615b604e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:615b8916-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:615bb24c-6b31-11ec-b3df-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:615bdb14-6b31-11ec-b3df-0242ac110002 UniProtKB:O60331 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:615c04e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:615c2dbc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:615c57c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:615c80a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:4118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pazopanib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:615ca968-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.26']} DrugCentral uuid:615cd262-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.328']} DrugCentral uuid:615cfb7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:615d2456-6b31-11ec-b3df-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.604']} DrugCentral uuid:615d4d28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.523']} DrugCentral uuid:615d7604-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:615d9f44-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:615dc816-6b31-11ec-b3df-0242ac110002 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.292']} DrugCentral uuid:615df0ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:615e19b0-6b31-11ec-b3df-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.44']} DrugCentral uuid:615e48ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:615e48ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.74']} DrugCentral uuid:615e81a2-6b31-11ec-b3df-0242ac110002 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:615e81a2-6b31-11ec-b3df-0242ac110002 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.82']} DrugCentral uuid:615eb654-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z2V5 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:615f0550-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:615f0550-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:615f0550-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:615f0550-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:615f0550-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:615f0550-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:615f0550-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:615f0550-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:615f0550-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:615f0550-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:615f0550-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4119 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romidepsin is inhibitor of Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:615fa848-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14833 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:615fd11a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14831 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine is agonist of GPCR (Metabotropic glutamate receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:615ffba4-6b31-11ec-b3df-0242ac110002 UniProtKB:O15303 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine is agonist of GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:616025ac-6b31-11ec-b3df-0242ac110002 UniProtKB:O00222 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine is agonist of GPCR (Metabotropic glutamate receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:61604e60-6b31-11ec-b3df-0242ac110002 UniProtKB:P31423 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine targets GPCR (Metabotropic glutamate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:6160771e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35349 biolink:molecularly_interacts_with DrugCentral:4120 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexfosfoserine targets GPCR (Metabotropic glutamate receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:6160a054-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:6160c944-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:6160f23e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:61611b1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.223']} DrugCentral uuid:61614450-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.02']} DrugCentral uuid:61616d40-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.405']} DrugCentral uuid:616195f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets Enzyme (Arachidonate 5-lipoxygenase) DrugCentral uuid:6161ba70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets Enzyme (Thioredoxin reductase 1, cytoplasmic) DrugCentral uuid:6161e1d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.922']} DrugCentral uuid:61620bc4-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4122 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 auranofin is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:6162348c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51788 biolink:molecularly_interacts_with DrugCentral:4123 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lubiprostone is opener of Ion channel (Chloride channel protein 2) DrugCentral uuid:61625908-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:61628248-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:6162ab4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:6162d43c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.3']} DrugCentral uuid:6162fe4e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:6163278e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.89']} DrugCentral uuid:6163507e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:61637950-6b31-11ec-b3df-0242ac110002 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:6163a3a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:6163cc7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P09960 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:6163f54c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:61641e32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q94F81 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (HD2 type histone deacetylase HDA106; Histone deacetylase 2b; Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:6164479a-6b31-11ec-b3df-0242ac110002 UniProtKB:O09106 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:6164706c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ZTP8 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:61649952-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XYC7 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:6164c29c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q70I53 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase-like amidohydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:6164ebd2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:616514c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7K6A1 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:61653d8a-6b31-11ec-b3df-0242ac110002 UniProtKB:B2RXH2 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Lysine-specific demethylase 4E) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.85']} DrugCentral uuid:61656652-6b31-11ec-b3df-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:616594c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:616594c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y618 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:6165ced0-6b31-11ec-b3df-0242ac110002 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:6165ced0-6b31-11ec-b3df-0242ac110002 UniProtKB:O75376 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Transcription factor (Histone deacetylase 3/NCoR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.92']} DrugCentral uuid:616629f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:616629f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:616629f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:616629f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:616629f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:616629f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:616629f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:616629f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:616629f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:616629f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:616629f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:6166d712-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:6166d712-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:6166d712-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:6166d712-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase 1/3/5/8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:61672780-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase (HDAC1 and HDAC2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:61672780-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase (HDAC1 and HDAC2)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:6167776c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:6167776c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:6167776c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:6167776c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:6167776c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:6167776c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:6167776c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99P99 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.78']} DrugCentral uuid:6167e8aa-6b31-11ec-b3df-0242ac110002 UniProtKB:A5H660 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Unclassified (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:61681186-6b31-11ec-b3df-0242ac110002 UniProtKB:P24527 biolink:molecularly_interacts_with DrugCentral:4124 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorinostat targets Enzyme (Leukotriene A-4 hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:61683a62-6b31-11ec-b3df-0242ac110002 UniProtKB:P12821 biolink:molecularly_interacts_with DrugCentral:4125 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proline targets Enzyme (Angiotensin-converting enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:6168632a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35439 biolink:molecularly_interacts_with DrugCentral:4125 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 proline targets Ion channel (Glutamate receptor ionotropic, NMDA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.76']} DrugCentral uuid:61688c4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z1J7 biolink:molecularly_interacts_with DrugCentral:4126 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asparagine targets Transporter (Amino acid transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:6168b514-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:6168dddc-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:6169078a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07314 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Enzyme (Gamma-glutamyltranspeptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.3']} DrugCentral uuid:61693232-6b31-11ec-b3df-0242ac110002 UniProtKB:P63116 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Unclassified (Asc-type amino acid transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:61695af0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z1J7 biolink:molecularly_interacts_with DrugCentral:4127 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 serine targets Transporter (Amino acid transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:616983e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01650 biolink:molecularly_interacts_with DrugCentral:4128 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valine targets Transporter (Large neutral amino acids transporter small subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.17']} DrugCentral uuid:6169ac9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06278 biolink:molecularly_interacts_with DrugCentral:4134 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyridoxal targets Enzyme (Aldehyde oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:6169d5fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisdexamfetamine is releasing agent of Transporter (Sodium-dependent noradrenaline transporter) DrugCentral uuid:6169fa8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisdexamfetamine is releasing agent of Transporter (Sodium-dependent dopamine transporter) DrugCentral uuid:616a1f26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:4135 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lisdexamfetamine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:616a43a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:616a6cc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.301']} DrugCentral uuid:616a96ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.387']} DrugCentral uuid:616ac0c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.925']} DrugCentral uuid:616ae992-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:616b1642-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:616b423e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.218']} DrugCentral uuid:616b6b38-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.209']} DrugCentral uuid:616b9464-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:616bbd4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.617']} DrugCentral uuid:616be61c-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.569']} DrugCentral uuid:616c0f02-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.553']} DrugCentral uuid:616c3810-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.635']} DrugCentral uuid:616c60e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:616c89d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:616cb29a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.251']} DrugCentral uuid:616cdcfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.916']} DrugCentral uuid:616d05d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3N8 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Histamine H4 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.061']} DrugCentral uuid:616d2f9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:616d5880-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:616d81ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.195']} DrugCentral uuid:616daa9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.265']} DrugCentral uuid:616dd346-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.155']} DrugCentral uuid:616dfc18-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.556']} DrugCentral uuid:616e256c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28566 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (5-hydroxytryptamine receptor 1E) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.991']} DrugCentral uuid:616e4e66-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:616e7742-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.47']} DrugCentral uuid:616ea19a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:616eccb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.06']} DrugCentral uuid:616ef596-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.809']} DrugCentral uuid:616f1e5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.975']} DrugCentral uuid:616f47bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:616f7084-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.697']} DrugCentral uuid:616f9974-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:616fc228-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.124']} DrugCentral uuid:616febcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.241']} DrugCentral uuid:61701494-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.55']} DrugCentral uuid:61703d7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.945']} DrugCentral uuid:61706656-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.578']} DrugCentral uuid:617090d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.294']} DrugCentral uuid:6170b9b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.037']} DrugCentral uuid:6170e28e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:61710bce-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.416']} DrugCentral uuid:617135a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.562']} DrugCentral uuid:61715fc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:61718892-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.084']} DrugCentral uuid:6171b2ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.628']} DrugCentral uuid:6171dc7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.012']} DrugCentral uuid:6172056a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.21']} DrugCentral uuid:61722e3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.233']} DrugCentral uuid:6172595c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.325']} DrugCentral uuid:6172831e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.668']} DrugCentral uuid:6172ac04-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.252']} DrugCentral uuid:6172d4d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:6172fe3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:4138 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentian violet targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.701']} DrugCentral uuid:61732788-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 udenafil targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:61734c18-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:4141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 udenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.084']} DrugCentral uuid:617374fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:4142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine silver is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:61739a24-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfadiazine silver targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:6173c2f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:6173ebc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.658']} DrugCentral uuid:617414c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72874 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir is inhibitor of Enzyme (Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.85']} DrugCentral uuid:61743eac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.21']} DrugCentral uuid:61746788-6b31-11ec-b3df-0242ac110002 UniProtKB:O90781 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.96']} DrugCentral uuid:6174905a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:6174b99a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ30 biolink:molecularly_interacts_with DrugCentral:4143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darunavir targets Unclassified (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.82']} DrugCentral uuid:6174e28a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:4144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium lauryl sulfate targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:61750b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:4144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium lauryl sulfate targets Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:61753424-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone propionate is agonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:61755ea4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:4146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone propionate targets Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.25']} DrugCentral uuid:61758780-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4146 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone propionate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6175c704-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6175c704-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6175c704-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6175c704-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6175c704-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6175c704-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6175c704-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doripenem is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:61762abe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.55']} DrugCentral uuid:6176537c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:61767c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:6176a5ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14330 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (N-arachidonyl glycine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:6176ce74-6b31-11ec-b3df-0242ac110002 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:6176f75a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:617720d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P47746 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:61774a98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant targets GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:6177737e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:4150 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimonabant is antagonist of GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.72']} DrugCentral uuid:61779db8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:6177c78e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:6177ec3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin is antagonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.44']} DrugCentral uuid:6178150e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:61783dfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:61786748-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 silodosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:6178902e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2VKV7 biolink:molecularly_interacts_with DrugCentral:4152 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 permethrin is blocker of Ion channel (Sodium channel protein) DrugCentral uuid:6178d354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6178d354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6178d354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6178d354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6178d354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6178d354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6178d354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6178d354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6178d354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4153 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabazitaxel is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:61794ce4-6b31-11ec-b3df-0242ac110002 UniProtKB:P39654 biolink:molecularly_interacts_with DrugCentral:4156 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edaravone targets Enzyme (Polyunsaturated fatty acid lipoxygenase ALOX15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.47']} DrugCentral uuid:61797994-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lercanidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:61797994-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:4157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lercanidipine is blocker of Ion channel (Voltage-gated L-type calcium channel) DrugCentral uuid:6179aa36-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temsirolimus targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:6179cebc-6b31-11ec-b3df-0242ac110002 UniProtKB:P62942 biolink:molecularly_interacts_with DrugCentral:4161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temsirolimus is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP1A) DrugCentral uuid:6179f3c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:4161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temsirolimus targets Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:617a1c78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00688 biolink:molecularly_interacts_with DrugCentral:4161 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 temsirolimus targets Enzyme (Peptidyl-prolyl cis-trans isomerase FKBP3) DrugCentral uuid:617a454a-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexlansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:617a454a-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexlansoprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:617a7448-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:4162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexlansoprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:617a9d42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:4162 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexlansoprazole targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617b5b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Voltage-gated potassium channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:617d5f32-6b31-11ec-b3df-0242ac110002 UniProtKB:P15388 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:617d880e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22462 biolink:molecularly_interacts_with DrugCentral:4163 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fampridine is blocker of Ion channel (Potassium voltage-gated channel subfamily C member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:617db0e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 liraglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.2']} DrugCentral uuid:617dd9b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alcaftadine is antagonist of GPCR (Histamine H1 receptor) DrugCentral uuid:617dfece-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4166 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ulipristal is antagonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:617e282c-6b31-11ec-b3df-0242ac110002 UniProtKB:O95470 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod targets Enzyme (Sphingosine-1-phosphate lyase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:617e5108-6b31-11ec-b3df-0242ac110002 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:617e7a3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:617ea324-6b31-11ec-b3df-0242ac110002 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:617ecbec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is agonist of GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:617ef4b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923J1 biolink:molecularly_interacts_with DrugCentral:4167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fingolimod is blocker of Ion channel (Transient receptor potential cation channel subfamily M member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:617f1eda-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.39']} DrugCentral uuid:617f47fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.195']} DrugCentral uuid:617f70ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.305']} DrugCentral uuid:617f99be-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.967']} DrugCentral uuid:617fc330-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:617fec2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.17']} DrugCentral uuid:618014fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.69']} DrugCentral uuid:61803f22-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.003']} DrugCentral uuid:6180695c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4168 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lurasidone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.328']} DrugCentral uuid:6180a908-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6180a908-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6180a908-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6180a908-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6180a908-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6180a908-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6180a908-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftaroline fosamil is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:61810f2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02643 biolink:molecularly_interacts_with DrugCentral:4170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tesamorelin is agonist of GPCR (Growth hormone-releasing hormone receptor) DrugCentral uuid:61815254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:61815254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:61815254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:61815254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:61815254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:61815254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:61815254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:61815254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:61815254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4171 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eribulin is inhibitor of Tumour-associated antigen (Tubulin beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.23']} DrugCentral uuid:6181db7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:61820438-6b31-11ec-b3df-0242ac110002 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:61822d5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:61825622-6b31-11ec-b3df-0242ac110002 UniProtKB:P23946 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Chymase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:61827ed6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir is inhibitor of Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:6182a78a-6b31-11ec-b3df-0242ac110002 UniProtKB:O60911 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin L2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:6182d16a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43235 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin K) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:6182fa32-6b31-11ec-b3df-0242ac110002 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:618322fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBX1 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Enzyme (Cathepsin F) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:618350a4-6b31-11ec-b3df-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:618350a4-6b31-11ec-b3df-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:618385e2-6b31-11ec-b3df-0242ac110002 UniProtKB:A0A0K1CY61 biolink:molecularly_interacts_with DrugCentral:4172 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 boceprevir targets Unclassified (Nonstructural protein NS3-4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:6183aec8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:6183d79a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08246 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Neutrophil elastase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:61840102-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNI1 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Chymotrypsin-like elastase family member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:618429b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:6184526a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:61847b1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23946 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Chymase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:6184a60c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10619 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir is inhibitor of Enzyme (Lysosomal protective protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:6184d168-6b31-11ec-b3df-0242ac110002 UniProtKB:O60911 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin L2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:6184fa3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43235 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin K) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:618523a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:618550b6-6b31-11ec-b3df-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) DrugCentral uuid:618550b6-6b31-11ec-b3df-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) DrugCentral uuid:61858108-6b31-11ec-b3df-0242ac110002 UniProtKB:C1KIQ2 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.89']} DrugCentral uuid:6185a9d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0ZMF1 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.09']} DrugCentral uuid:6185d36a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q91RS4 biolink:molecularly_interacts_with DrugCentral:4173 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telaprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:6185fc46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:61862522-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) DrugCentral uuid:618649a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:6186731a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:61869bd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WJQ2 biolink:molecularly_interacts_with DrugCentral:4174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilpivirine targets Unclassified (Reverse transcriptase protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:6186c4a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:6186ed72-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:6187169e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:61874056-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:61876928-6b31-11ec-b3df-0242ac110002 UniProtKB:P97321 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:618791e6-6b31-11ec-b3df-0242ac110002 UniProtKB:O31048 biolink:molecularly_interacts_with DrugCentral:4175 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linagliptin targets Unclassified (Dipeptidyl peptidase IV) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:6187bb62-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:6187e42a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:61880d24-6b31-11ec-b3df-0242ac110002 UniProtKB:P05093 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate is inhibitor of Enzyme (Steroid 17-alpha-hydroxylase/17,20 lyase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.54']} DrugCentral uuid:618835f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.79']} DrugCentral uuid:61886026-6b31-11ec-b3df-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:6188890c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11715 biolink:molecularly_interacts_with DrugCentral:4176 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abiraterone acetate targets Enzyme (Cytochrome P450 17A1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:6188b1e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P54289 biolink:molecularly_interacts_with DrugCentral:4177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin enacarbil is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-1) DrugCentral uuid:6188d68c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY47 biolink:molecularly_interacts_with DrugCentral:4177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gabapentin enacarbil is modulator of Ion channel (Voltage-dependent calcium channel subunit alpha-2/delta-2) DrugCentral uuid:6188fb76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:61892448-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:61894d92-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:6189772c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.47']} DrugCentral uuid:6189a01c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:6189c902-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.15']} DrugCentral uuid:6189f1de-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:618a1c2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:618a45f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:618a6ede-6b31-11ec-b3df-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:618a97b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:618ac190-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:618aea80-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:618b1366-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:618b3d50-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:618b66ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:618b8fa8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:618bb88e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:618be16a-6b31-11ec-b3df-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:618c0c80-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:618c3570-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:618c5e4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:618c8796-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:618cb07c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:618cd962-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:618d0252-6b31-11ec-b3df-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:618d2bb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:618d5496-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:618d7d5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:618da630-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:618dd15a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:618dfa36-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:618e2308-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:618e4c0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:618e751a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.16']} DrugCentral uuid:618e9e00-6b31-11ec-b3df-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:618ec6e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:618eefb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:618f1952-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.3']} DrugCentral uuid:618f431e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:618f6c0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:618f9648-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:618fbfe2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:618fe8c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:6190119a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:61903ada-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:619063ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:61908c92-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:6190b56e-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.34']} DrugCentral uuid:6190def4-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:619107d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:619130b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:61915a14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:61918462-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:6191ad48-6b31-11ec-b3df-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:6191d61a-6b31-11ec-b3df-0242ac110002 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:6191feec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:61922836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:619250fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:619279ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:6192a37e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:6192cc6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:6192f6b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:61931f98-6b31-11ec-b3df-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:61934b8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:619375ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61939eb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:6193c790-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:6193f0d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:619419a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:61944274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:61946b3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:619494b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:6194bd8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:6194e65c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:61951014-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:619538f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6DT37 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase MRCK gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:619561cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:61958ab2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:6195b6ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:6195df8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:61960866-6b31-11ec-b3df-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:6196312e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:61965aa0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5VT25 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase MRCK alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:6196837c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:6196ac44-6b31-11ec-b3df-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:6196d520-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:619700ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:619729b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6197536a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:61977c5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:6197a5d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:6197ceb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16659 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:6197f77a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:6198215a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:61984a2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61987308-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:61989c48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:6198c5ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:6198eea0-6b31-11ec-b3df-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:6199177c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:6199404e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:619969d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:619992b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:6199bcfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:6199e5ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:619a0f24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:619a3800-6b31-11ec-b3df-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:619a60dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WU08 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Serine/threonine-protein kinase 32A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:619a89c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4178 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vandetanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:619ac144-6b31-11ec-b3df-0242ac110002 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:619ac144-6b31-11ec-b3df-0242ac110002 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:619ac144-6b31-11ec-b3df-0242ac110002 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:619ac144-6b31-11ec-b3df-0242ac110002 UniProtKB:Q18CI5 biolink:molecularly_interacts_with DrugCentral:4180 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fidaxomicin is inhibitor of Enzyme (DNA-directed RNA polymerase) DrugCentral uuid:619b0514-6b31-11ec-b3df-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:619b2f9e-6b31-11ec-b3df-0242ac110002 UniProtKB:O43525 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:619b5866-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:619b812e-6b31-11ec-b3df-0242ac110002 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:619ba9f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z351 biolink:molecularly_interacts_with DrugCentral:4181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 retigabine targets Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:619bd336-6b31-11ec-b3df-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:4182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivaroxaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:619bfbfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y6 biolink:molecularly_interacts_with DrugCentral:4182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivaroxaban targets Enzyme (Suppressor of tumorigenicity 14 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.47']} DrugCentral uuid:619c24e4-6b31-11ec-b3df-0242ac110002 UniProtKB:O19045 biolink:molecularly_interacts_with DrugCentral:4182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rivaroxaban targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.29']} DrugCentral uuid:619c4db6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.04']} DrugCentral uuid:619c7958-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:619ca41e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:619cccd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.98']} DrugCentral uuid:619cf5a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 indacaterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.1']} DrugCentral uuid:619d1f3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:4184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticagrelor is negative allosteric modulator of GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:619d4842-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99808 biolink:molecularly_interacts_with DrugCentral:4184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticagrelor is inhibitor of Transporter (Equilibrative nucleoside transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:619d7100-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EPX4 biolink:molecularly_interacts_with DrugCentral:4184 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ticagrelor targets GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:619d9a36-6b31-11ec-b3df-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:619dc31c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:619debe4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:619e1498-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:619e3e96-6b31-11ec-b3df-0242ac110002 UniProtKB:P10398 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (Serine/threonine-protein kinase A-Raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:619e6a88-6b31-11ec-b3df-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.78']} DrugCentral uuid:619e9350-6b31-11ec-b3df-0242ac110002 UniProtKB:P22830 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Enzyme (Ferrochelatase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:619ebc18-6b31-11ec-b3df-0242ac110002 UniProtKB:P28028 biolink:molecularly_interacts_with DrugCentral:4185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vemurafenib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:619ee594-6b31-11ec-b3df-0242ac110002 UniProtKB:P30411 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant is antagonist of GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.22']} DrugCentral uuid:619f0e84-6b31-11ec-b3df-0242ac110002 UniProtKB:P25023 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.11']} DrugCentral uuid:619f3846-6b31-11ec-b3df-0242ac110002 UniProtKB:O70526 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant targets GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.96']} DrugCentral uuid:619f610e-6b31-11ec-b3df-0242ac110002 UniProtKB:P46663 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant is antagonist of GPCR (B1 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:619f8b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P32299 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant is antagonist of GPCR (B2 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.6']} DrugCentral uuid:619fb44c-6b31-11ec-b3df-0242ac110002 UniProtKB:P97583 biolink:molecularly_interacts_with DrugCentral:4186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icatibant is antagonist of GPCR (B1 bradykinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.4']} DrugCentral uuid:619fdd1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:61a005e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.6']} DrugCentral uuid:61a02fda-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:61a05a00-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:61a082c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:61a0ac4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:61a0d548-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:61a0fe24-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:61a126f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:61a15040-6b31-11ec-b3df-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:61a1791c-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:61a1a1f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:61a1caca-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:61a1f5e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:61a220ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:61a249be-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:61a272a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:61a29c2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:61a2c506-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:61a2edd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:61a31718-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:61a340f8-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:61a369d4-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:61a392c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:61a3bce0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:61a3e620-6b31-11ec-b3df-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:61a40ee8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:61a4380a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.26']} DrugCentral uuid:61a461ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:61a48a80-6b31-11ec-b3df-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:61a4b352-6b31-11ec-b3df-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:61a4dc1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:61a505dc-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.36']} DrugCentral uuid:61a52e9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:61a55776-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.22']} DrugCentral uuid:61a58048-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:61a5ab5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:61a5d41c-6b31-11ec-b3df-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:61a5fcf8-6b31-11ec-b3df-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:61a6266a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:61a64f50-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:61a6782c-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:61a6a112-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.13']} DrugCentral uuid:61a6ca3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:61a6f310-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:61a71d04-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:61a746da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:61a770b0-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:61a799b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:61a7c2f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:61a7ebe4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:61a8154c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:61a83e3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:61a86718-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:61a88fea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:61a8b92a-6b31-11ec-b3df-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:61a8e206-6b31-11ec-b3df-0242ac110002 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:61a90ace-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:61a9349a-6b31-11ec-b3df-0242ac110002 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:61a95e16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:61a986e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:61a9afba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:61a9d922-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:61aa01f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:61aa2ad0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:61aa5398-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:61aa7cce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:61aaa5b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:61aace9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:61aaf762-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:61ab2250-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:61ab4c1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:61ab74f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:61ab9dca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:61abc7e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:61abf0ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:61ac198a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:61ac42ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:61ac6b92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:61ac946e-6b31-11ec-b3df-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:61acbd4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:61ace69e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:61ad0f70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:61ad3860-6b31-11ec-b3df-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:61ad613c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:61ad8b94-6b31-11ec-b3df-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:61adb45c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:61addd2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:61ae0736-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:61ae3080-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:61ae5948-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:61ae824c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:61aeab32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:61aed7a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:61af00c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:61af297c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:61af53e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:61af7cba-6b31-11ec-b3df-0242ac110002 UniProtKB:P21127 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase 11B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:61afa58c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ88 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase 11A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:61afce54-6b31-11ec-b3df-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:61aff78a-6b31-11ec-b3df-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:61b0205c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:61b0492e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TD19 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase Nek9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:61b0720a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:61b09cbc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:61b0c58e-6b31-11ec-b3df-0242ac110002 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:61b0ee6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:61b11750-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:61b140cc-6b31-11ec-b3df-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:61b169a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:61b19284-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61b1bb56-6b31-11ec-b3df-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:61b1e4be-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.39']} DrugCentral uuid:61b20dae-6b31-11ec-b3df-0242ac110002 UniProtKB:P00520 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:61b23680-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:61b26024-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:61b288f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:61b2b254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:61b2db30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:61b304ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:61b32d9c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:61b3575e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:61b3803a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:61b3a970-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:61b3d242-6b31-11ec-b3df-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:61b3fb1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:61b423f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:61b45000-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:61b478dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.09']} DrugCentral uuid:61b4a1a4-6b31-11ec-b3df-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:61b4cc74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:61b4f550-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:61b51e2c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:61b546fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61b57048-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:61b5992e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:61b5c20a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:61b5eae6-6b31-11ec-b3df-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:61b614d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:61b63da2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:61b66692-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:61b68f50-6b31-11ec-b3df-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:61b6b8f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62190 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:61b6e1c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02858 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:61b70b10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:61b734c8-6b31-11ec-b3df-0242ac110002 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:61b75e08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:61b78702-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:61b7afde-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:61b7dd6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:61b7dd6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.29']} DrugCentral uuid:61b81258-6b31-11ec-b3df-0242ac110002 UniProtKB:O15357 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Enzyme (Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.26']} DrugCentral uuid:61b83b20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:61b86410-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NB16 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Mixed lineage kinase domain-like protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:61b88da0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4187 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizotinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:61b8b672-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BU89 biolink:molecularly_interacts_with DrugCentral:4188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deferiprone targets Enzyme (Deoxyhypusine hydroxylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:61b8dff8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.638']} DrugCentral uuid:61b908e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.261']} DrugCentral uuid:61b9323c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.573']} DrugCentral uuid:61b95b18-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.74']} DrugCentral uuid:61b983f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04278 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Secreted (Sex hormone-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:61b9adb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.501']} DrugCentral uuid:61b9d6ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.307']} DrugCentral uuid:61b9ffaa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.81']} DrugCentral uuid:61ba289a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4189 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydroxyprogesterone caproate is agonist of Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.664']} DrugCentral uuid:61ba520c-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:61ba7ae8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:61baa3a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:61bacc8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:61baf6e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:61bb1fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:61bb487e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:61bb7150-6b31-11ec-b3df-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:61bb9e3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:61bbc8bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:61bbf17a-6b31-11ec-b3df-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:61bc1a60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.22']} DrugCentral uuid:61bc4422-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:61bc6cf4-6b31-11ec-b3df-0242ac110002 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:61bc95d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:61bcbf10-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:61bce7f6-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.44']} DrugCentral uuid:61bd10c8-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:61bd399a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:61bd630c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:61bd8bde-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:61bdb4b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:61bddd8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:61be071c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:61be300c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:61be58e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:61be81d8-6b31-11ec-b3df-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:61beab0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:61bed4f8-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:61befe60-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:61bf2728-6b31-11ec-b3df-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:61bf51e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:61bf7aac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:61bfa374-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:61bfcd18-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:61bff5fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:61c01eda-6b31-11ec-b3df-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:61c047ac-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:61c070ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:61c099c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:61c0c290-6b31-11ec-b3df-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:61c0eb58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:61c11664-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:61c13f4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:61c16812-6b31-11ec-b3df-0242ac110002 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:61c190f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:61c1ba88-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:61c1e346-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:61c20c18-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:61c234f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:61c25f74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:61c2883c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.49']} DrugCentral uuid:61c2b12c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:61c2dc6a-6b31-11ec-b3df-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:61c305dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:61c32eea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:61c357bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:61c38142-6b31-11ec-b3df-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:61c3aa1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:61c3d2fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:61c3fbd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:61c42516-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:61c44dde-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:61c476b0-6b31-11ec-b3df-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:61c49f78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:61c4ca34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:61c4f310-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:61c51bf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:61c54554-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:61c56e3a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:61c59716-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:61c5c088-6b31-11ec-b3df-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:61c5e9be-6b31-11ec-b3df-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:61c612a4-6b31-11ec-b3df-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.17']} DrugCentral uuid:61c63b6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:61c664c0-6b31-11ec-b3df-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61c68e78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:61c6b74a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:61c6e12a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:61c70a10-6b31-11ec-b3df-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:61c73382-6b31-11ec-b3df-0242ac110002 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:61c75c4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:61c78512-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:61c7adf8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:61c7d74c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:61c80014-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:61c828f0-6b31-11ec-b3df-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:61c85244-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:61c87d78-6b31-11ec-b3df-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:61c8a62c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:61c8cefe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:61c8f83e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:61c92124-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:61c94b22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:61c973ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:61c99d5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:61c9c642-6b31-11ec-b3df-0242ac110002 UniProtKB:O95747 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase OSR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:61c9ef00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:61ca17f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:61ca4216-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:61ca6ae8-6b31-11ec-b3df-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:61ca93a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:61cabd68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:61cae6a8-6b31-11ec-b3df-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:61cb0f84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:61cb3856-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:61cb61a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:61cb8a7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:61cbb358-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:61cbdc20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:61cc065a-6b31-11ec-b3df-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:61cc3242-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:61cc5bb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:61cc847c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:61ccae0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:61ccd6f2-6b31-11ec-b3df-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:61ccffce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:61cd28a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P51956 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase Nek3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:61cd51e0-6b31-11ec-b3df-0242ac110002 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:61cd7ad0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86Y07 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase VRK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:61cda3a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:61cdcc6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:61cdf7b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62120 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.73']} DrugCentral uuid:61ce2066-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:61ce4d20-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:61ce4d20-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:61ce86a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:61ce86a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:61cec07a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:61cec07a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:61cefcf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:61cefcf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:61cefcf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:61cf420c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:61cf420c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:61cf77fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:61cfa0f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P55055 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Nuclear other (Oxysterols receptor LXR-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.35']} DrugCentral uuid:61cfcb3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62120 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.73']} DrugCentral uuid:61cff3fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4190 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ruxolitinib targets Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:61d01cae-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.393']} DrugCentral uuid:61d0465c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.401']} DrugCentral uuid:61d06f42-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.271']} DrugCentral uuid:61d0980a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.187']} DrugCentral uuid:61d0c0d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4191 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fesoterodine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.979']} DrugCentral uuid:61d0ea26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:4192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafamidis is inhibitor of Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.936']} DrugCentral uuid:61d11302-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:4192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafamidis is inhibitor of Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.538']} DrugCentral uuid:61d13be8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:4192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafamidis is inhibitor of Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.627']} DrugCentral uuid:61d164d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:4192 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafamidis is binding agent of Secreted (Transthyretin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.812']} DrugCentral uuid:61d18fee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99707 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Enzyme (Methionine synthase) DrugCentral uuid:61d1b460-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBK8 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Enzyme (Methionine synthase reductase) DrugCentral uuid:61d1d8d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BXJ7 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Unclassified (Protein amnionless) DrugCentral uuid:61d1fd30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96EY8 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Enzyme (Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial) DrugCentral uuid:61d22242-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH4 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Enzyme (Methylmalonic aciduria type A protein, mitochondrial) DrugCentral uuid:61d24826-6b31-11ec-b3df-0242ac110002 UniProtKB:P20062 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Secreted (Transcobalamin-2) DrugCentral uuid:61d26ca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P20061 biolink:molecularly_interacts_with DrugCentral:4196 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cyanocobalamin targets Secreted (Transcobalamin-1) DrugCentral uuid:61d2911e-6b31-11ec-b3df-0242ac110002 UniProtKB:P02753 biolink:molecularly_interacts_with DrugCentral:4197 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vitamin A palmitate targets Secreted (Retinol-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:61d2ba54-6b31-11ec-b3df-0242ac110002 UniProtKB:P02754 biolink:molecularly_interacts_with DrugCentral:4197 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vitamin A palmitate targets Unclassified (Beta-lactoglobulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:61d2e33a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4199 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 potassium chloride targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.05']} DrugCentral uuid:61d30c16-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium acetate targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.97']} DrugCentral uuid:61d334e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium acetate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.44']} DrugCentral uuid:61d36288-6b31-11ec-b3df-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium carbonate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:61d36288-6b31-11ec-b3df-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium carbonate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:61d39186-6b31-11ec-b3df-0242ac110002 UniProtKB:P29218 biolink:molecularly_interacts_with DrugCentral:4207 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium carbonate is inhibitor of Enzyme (Inositol-1(or 4)-monophosphatase 1) DrugCentral uuid:61d3b602-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:61d3ded4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61d40814-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.73']} DrugCentral uuid:61d43104-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.582']} DrugCentral uuid:61d45a08-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin is inverse agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:61d482ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:61d4acb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.48']} DrugCentral uuid:61d4d58c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:61d4fe68-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:61d5283e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:61d551ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin is inverse agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:61d57aaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin is inverse agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.68']} DrugCentral uuid:61d5a408-6b31-11ec-b3df-0242ac110002 UniProtKB:P16083 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Enzyme (Ribosyldihydronicotinamide dehydrogenase [quinone]) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:61d5cd2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14780 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Enzyme (Matrix metalloproteinase-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.157']} DrugCentral uuid:61d5f5fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P03956 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Enzyme (Interstitial collagenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.394']} DrugCentral uuid:61d61ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:61d649b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10']} DrugCentral uuid:61d67356-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:61d69c46-6b31-11ec-b3df-0242ac110002 UniProtKB:P23944 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:61d6c52c-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:61d6edfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:61d71a40-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.63']} DrugCentral uuid:61d743da-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.82']} DrugCentral uuid:61d76cca-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.78']} DrugCentral uuid:61d795f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P18130 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:61d7bedc-6b31-11ec-b3df-0242ac110002 UniProtKB:P18871 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.39']} DrugCentral uuid:61d7e830-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28838 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:61d81134-6b31-11ec-b3df-0242ac110002 UniProtKB:P18841 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:61d83aa6-6b31-11ec-b3df-0242ac110002 UniProtKB:O15244 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Transporter (Solute carrier family 22 member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.87']} DrugCentral uuid:61d8636e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96FL8 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Transporter (Multidrug and toxin extrusion protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61d88c40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86VL8 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Transporter (Multidrug and toxin extrusion protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:61d8bcba-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:61d8bcba-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:61d8bcba-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.4']} DrugCentral uuid:61d908aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.99']} DrugCentral uuid:61d908aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.99']} DrugCentral uuid:61d908aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.99']} DrugCentral uuid:61d9512a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:61d9512a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:61d9512a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:61d99a04-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:61d99a04-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:61d99a04-6b31-11ec-b3df-0242ac110002 UniProtKB:P30994 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Serotonin 2 (5-HT2) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:61d9e37e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:61d9e37e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:61d9e37e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01338 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets GPCR (Alpha-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:61da24d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P02665 biolink:molecularly_interacts_with DrugCentral:4209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prazosin targets Unclassified (Beta-casein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:61da4db4-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetic acid targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:61da7672-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetic acid targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:61da9f4e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15552 biolink:molecularly_interacts_with DrugCentral:4211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetic acid is agonist of GPCR (Free fatty acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:61dac94c-6b31-11ec-b3df-0242ac110002 UniProtKB:O14843 biolink:molecularly_interacts_with DrugCentral:4211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acetic acid targets GPCR (Free fatty acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:61daf21e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:61db169a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08185 biolink:molecularly_interacts_with DrugCentral:4213 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone acetate targets Secreted (Corticosteroid-binding globulin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:61db480e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopate is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:61db480e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopate is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:61db480e-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methyldopate is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:61db8166-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4219 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium phosphate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:61dbab8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03732 biolink:molecularly_interacts_with DrugCentral:4220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telbivudine targets Unclassified (Capsid protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:61dbd472-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9IF40 biolink:molecularly_interacts_with DrugCentral:4220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telbivudine is inhibitor of Polyprotein (Protein P) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.886']} DrugCentral uuid:61dbfda8-6b31-11ec-b3df-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4221 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mequinol is inhibitor of Enzyme (Tyrosinase) DrugCentral uuid:61dc2242-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:61dc4b14-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:61dc73fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:61dca082-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:61dccc56-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:61dcf758-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:61dd20a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13639 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone is agonist of GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:61dd496a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28564 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:61dd7340-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:61dd9c1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:61ddc552-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:61ddee9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:61de175a-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:61de4018-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.67']} DrugCentral uuid:61de6b1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08909 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:61de93d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62758 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:61debc96-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:61dee554-6b31-11ec-b3df-0242ac110002 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:61df0ebc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:61df377a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:61df642a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:61df642a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JJ16 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets Ion channel (Serotonin 3 (5-HT3) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.37']} DrugCentral uuid:61dfa110-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:61dfa110-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:61dfa110-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:61dfe9a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:61dfe9a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:61dfe9a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:61e02b6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilazodone targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.41']} DrugCentral uuid:61e05448-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:61e07d06-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:61e0a5c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:61e0cf40-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.31']} DrugCentral uuid:61e0f916-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:61e121fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:61e14ad8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:61e17404-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:61e19ce0-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:61e1c5da-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.24']} DrugCentral uuid:61e1eeca-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.23']} DrugCentral uuid:61e21be8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:61e244c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:61e26d96-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.29']} DrugCentral uuid:61e29712-6b31-11ec-b3df-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:61e2bfe4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:61e2e8ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:61e311a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:61e33ae6-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:61e363ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:61e38cda-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:61e3b5b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:61e3dfe6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:61e408c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:61e43194-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:61e45a70-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:61e483e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:61e4acc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.89']} DrugCentral uuid:61e4d61c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:61e5004c-6b31-11ec-b3df-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:61e5296e-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.15']} DrugCentral uuid:61e5524a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:61e57b30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:61e5a542-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:61e5cf0e-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:61e5f7d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:61e620b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:61e64a2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.25']} DrugCentral uuid:61e672ec-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:61e69bd2-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:61e6c4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:61e6ee0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:61e716e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:61e73fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:61e76896-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:61e79334-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:61e7bc10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:61e7e4ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:61e80dd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:61e83762-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:61e86034-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:61e88910-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:61e8b264-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:61e8dc6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:61e90638-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:61e92f0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:61e958ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:61e981d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:61e9aaa2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:61e9d374-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:61e9fcdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:61ea25c2-6b31-11ec-b3df-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:61ea4ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:61ea777a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13705 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Activin receptor type-2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:61eaa0ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:61eac9be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:61eaf290-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:61eb1b6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:61eb452e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:61eb6dec-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:61eb96b4-6b31-11ec-b3df-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:61ebc080-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:61ebe966-6b31-11ec-b3df-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:61ec1238-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5S2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase MRCK beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:61ec3b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NEV4 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Myosin-IIIa) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:61ec647c-6b31-11ec-b3df-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:61ec8d44-6b31-11ec-b3df-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:61ecb602-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:61ecdf2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:61ed0b02-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:61ed33de-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:61ed5cc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:61ed8596-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:61edaef4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:61edd7d0-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:61ee00a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:61ee29f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:61ee52dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:61ee7bb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:61eea49e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:61eecea6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:61eef836-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:61ef2108-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:61ef49e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:61ef7324-6b31-11ec-b3df-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:61ef9bec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:61efc5fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:61efeeda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:61f01856-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4225 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 axitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:61f04132-6b31-11ec-b3df-0242ac110002 UniProtKB:P05129 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate is activator of Kinase (Protein kinase C gamma type) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.79']} DrugCentral uuid:61f06a22-6b31-11ec-b3df-0242ac110002 UniProtKB:P05771 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate targets Kinase (Protein kinase C beta type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.836']} DrugCentral uuid:61f092f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.197']} DrugCentral uuid:61f0bcc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.959']} DrugCentral uuid:61f0e588-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.523']} DrugCentral uuid:61f10fae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:4226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ingenol mebutate is activator of Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.328']} DrugCentral uuid:61f138e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62226 biolink:molecularly_interacts_with DrugCentral:4227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vismodegib targets Enzyme (Sonic hedgehog protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:61f161de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15465 biolink:molecularly_interacts_with DrugCentral:4227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vismodegib targets Enzyme (Sonic hedgehog protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:61f18ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:4227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vismodegib is inhibitor of GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.79']} DrugCentral uuid:61f1b3b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P56726 biolink:molecularly_interacts_with DrugCentral:4227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vismodegib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:61f1ddd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:4228 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivacaftor is positive modulator of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:61f20698-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:4229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafluprost is agonist of GPCR (Prostaglandin F2-alpha receptor) DrugCentral uuid:61f22b32-6b31-11ec-b3df-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:4234 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginesatide is agonist of Membrane receptor (Erythropoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.43']} DrugCentral uuid:61f25422-6b31-11ec-b3df-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avobenzone is inhibitor of Enzyme (Tyrosinase) DrugCentral uuid:61f27a06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin targets Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:61f2a350-6b31-11ec-b3df-0242ac110002 UniProtKB:P15917 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin targets Enzyme (Lethal factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.3']} DrugCentral uuid:61f2cc4a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95237 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin targets Enzyme (Lecithin retinol acyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.83']} DrugCentral uuid:61f2f530-6b31-11ec-b3df-0242ac110002 UniProtKB:O00255 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin targets Unclassified (Menin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.81']} DrugCentral uuid:61f31e66-6b31-11ec-b3df-0242ac110002 UniProtKB:P48442 biolink:molecularly_interacts_with DrugCentral:4247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neomycin is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4']} DrugCentral uuid:61f34742-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.21']} DrugCentral uuid:61f37032-6b31-11ec-b3df-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:61f3990e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.76']} DrugCentral uuid:61f3c2a8-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.27']} DrugCentral uuid:61f3eb84-6b31-11ec-b3df-0242ac110002 UniProtKB:P51787 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:61f41460-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:61f43dbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.45']} DrugCentral uuid:61f46816-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:61f49124-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:61f4b9d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.79']} DrugCentral uuid:61f4e32c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:61f50d02-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:61f535f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc is activator of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:61f55eba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:4248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pyrithione zinc targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.38']} DrugCentral uuid:61f58c32-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:4257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bismuth subsalicylate is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:61f58c32-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:4257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bismuth subsalicylate is inhibitor of Enzyme (Cyclooxygenase) DrugCentral uuid:61f5bb12-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thymol targets Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:61f5e3f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8R455 biolink:molecularly_interacts_with DrugCentral:4258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thymol targets Ion channel (Transient receptor potential cation channel subfamily M member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:61f60cb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4QYD9 biolink:molecularly_interacts_with DrugCentral:4258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thymol targets Unclassified (Heat sensitive channel TRPV3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:61f63894-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfur targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.4']} DrugCentral uuid:61f663d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfur targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.22']} DrugCentral uuid:61f68cc2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H255 biolink:molecularly_interacts_with DrugCentral:4264 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carbamide targets GPCR (Olfactory receptor 51E2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.64']} DrugCentral uuid:61f6b5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentamicin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:61f6de98-6b31-11ec-b3df-0242ac110002 UniProtKB:P00376 biolink:molecularly_interacts_with DrugCentral:4265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentamicin targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:61f70760-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BLA8 biolink:molecularly_interacts_with DrugCentral:4265 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gentamicin is gating inhibitor of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:61f7303c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:61f75a4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:61f78334-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.02']} DrugCentral uuid:61f7ac24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:61f7d50a-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.04']} DrugCentral uuid:61f7ff30-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:61f8280c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.94']} DrugCentral uuid:61f850de-6b31-11ec-b3df-0242ac110002 UniProtKB:P00720 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Endolysin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.04']} DrugCentral uuid:61f879b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.98']} DrugCentral uuid:61f8a304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.76']} DrugCentral uuid:61f8cbea-6b31-11ec-b3df-0242ac110002 UniProtKB:P96878 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Probable transmembrane carbonic anhydrase (Carbonate dehydratase) (Carbonic dehydratase); Transmembrane carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:61f8f4da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.59']} DrugCentral uuid:61f91eba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.86']} DrugCentral uuid:61f94854-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPJ7 biolink:molecularly_interacts_with DrugCentral:4266 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenol targets Enzyme (Beta-carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.19']} DrugCentral uuid:61f97126-6b31-11ec-b3df-0242ac110002 UniProtKB:P14679 biolink:molecularly_interacts_with DrugCentral:4267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arbutin targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:61f999da-6b31-11ec-b3df-0242ac110002 UniProtKB:O42713 biolink:molecularly_interacts_with DrugCentral:4267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arbutin targets Enzyme (Polyphenol oxidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:61f9c342-6b31-11ec-b3df-0242ac110002 UniProtKB:P11344 biolink:molecularly_interacts_with DrugCentral:4267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arbutin targets Enzyme (Tyrosinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:61f9ec6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fa957e-6b31-11ec-b3df-0242ac110002 UniProtKB:E0W4F7 biolink:molecularly_interacts_with DrugCentral:4276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piperonyl butoxide is inhibitor of Enzyme (Cytochrome P450) DrugCentral uuid:61fc1f2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tapentadol is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.018']} DrugCentral uuid:61fc487e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tapentadol is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.319']} DrugCentral uuid:61fc7178-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tapentadol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:61fc9a4a-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tapentadol targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:61fcc308-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:4285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Florbetapir F-18 targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.54']} DrugCentral uuid:61fceca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:61fd157e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Nuclear hormone receptor (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:61fd3e8c-6b31-11ec-b3df-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent is agonist of GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:61fd6754-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:61fd92d8-6b31-11ec-b3df-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.82']} DrugCentral uuid:61fdbbbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDS5 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets GPCR (Oxoeicosanoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:61fde49a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6RI86 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:61fe0e66-6b31-11ec-b3df-0242ac110002 UniProtKB:P19793 biolink:molecularly_interacts_with DrugCentral:4289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doconexent targets Nuclear other (Retinoic acid receptor RXR-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:61fe3742-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 potassium iodide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.1']} DrugCentral uuid:61fe6028-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:4298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apixaban targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.51']} DrugCentral uuid:61fe890e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:4298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apixaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:61feb258-6b31-11ec-b3df-0242ac110002 UniProtKB:O19045 biolink:molecularly_interacts_with DrugCentral:4298 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apixaban targets Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:61fee6e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:61fee6e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:61fee6e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:61fee6e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HB55 biolink:molecularly_interacts_with DrugCentral:4299 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobicistat is inhibitor of Enzyme (Cytochrome P450 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.027']} DrugCentral uuid:61ff34b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P03367 biolink:molecularly_interacts_with DrugCentral:4300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elvitegravir targets Polyprotein (Gag-Pol polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:61ff60cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:4300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elvitegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:61ff89bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:4300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elvitegravir targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:61ffb266-6b31-11ec-b3df-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:4300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elvitegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:61ffdb10-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:4301 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Flutemetamol (18F) targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:6200045a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.69']} DrugCentral uuid:62002e94-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.25']} DrugCentral uuid:6200578e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:62008132-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:6200aa40-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glycopyrronium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.91']} DrugCentral uuid:6200f540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:6200f540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:6200f540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:6200f540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:6200f540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:6200f540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:6200f540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:6200f540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:6200f540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:6200f540-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y9 biolink:molecularly_interacts_with DrugCentral:4303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eslicarbazepine acetate is blocker of Ion channel (Sodium channel alpha subunit) DrugCentral uuid:62017b96-6b31-11ec-b3df-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:6201a47c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:6201cdd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P53792 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin targets Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:6201f698-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WWX8 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin targets Transporter (Sodium/myo-inositol cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.42']} DrugCentral uuid:62022064-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY91 biolink:molecularly_interacts_with DrugCentral:4304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapagliflozin targets Transporter (Low affinity sodium-glucose cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.87']} DrugCentral uuid:62024954-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:4305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avanafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.284']} DrugCentral uuid:620272e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P51160 biolink:molecularly_interacts_with DrugCentral:4305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avanafil targets Enzyme (Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.201']} DrugCentral uuid:62029ba2-6b31-11ec-b3df-0242ac110002 UniProtKB:O77746 biolink:molecularly_interacts_with DrugCentral:4305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avanafil targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:6202c848-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:4308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasofoxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:6202c848-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62986 biolink:molecularly_interacts_with DrugCentral:4308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasofoxifene targets Transcription factor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:6202ff3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasofoxifene is agonist of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:6203286a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasofoxifene is agonist of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:620351e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide is blocker of Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:62037b3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:6203a47a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.44']} DrugCentral uuid:6203cd4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.28']} DrugCentral uuid:6203f63c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.45']} DrugCentral uuid:62041f0e-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.43']} DrugCentral uuid:6204489e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:62047184-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.47']} DrugCentral uuid:62049a74-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:6204c472-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.43']} DrugCentral uuid:6204efc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.39']} DrugCentral uuid:6205188c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:6205417c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04775 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide is blocker of Ion channel (Sodium channel protein type 2 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:62056a9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.92']} DrugCentral uuid:6205937a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99N23 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Carbonic anhydrase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.34']} DrugCentral uuid:6205bc60-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Ion channel (Sodium channel protein type 3 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:6205e528-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16555 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Enzyme (Dihydropyrimidinase-related protein 2) DrugCentral uuid:62060c74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62968 biolink:molecularly_interacts_with DrugCentral:4310 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lacosamide targets Ion channel (Sodium channel protein type X alpha subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:6206353c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:62065dfa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:620686ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:6206b034-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:6206d8e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine is agonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:620701b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:62073a4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:62073a4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:62073a4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:62073a4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:62073a4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aceclidine targets GPCR (Muscarinic acetylcholine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.08']} DrugCentral uuid:62079300-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:4317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 euflavine targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:6207bbb4-6b31-11ec-b3df-0242ac110002 UniProtKB:O40947 biolink:molecularly_interacts_with DrugCentral:4317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 euflavine targets Unclassified (ORF 73) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:6207e512-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16665 biolink:molecularly_interacts_with DrugCentral:4317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 euflavine targets Transcription factor (Hypoxia-inducible factor 1-alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:62080dda-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:620836d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:62085fb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:62088b2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:6208b406-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:6208dcf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.3']} DrugCentral uuid:62090640-6b31-11ec-b3df-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:62092f1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:6209580c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:620980e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:6209ab4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:6209d4c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:6209fdac-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:620a2688-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:620a5162-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:620a7a84-6b31-11ec-b3df-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:620aa36a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:620acc46-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:620af590-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:620b1e80-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:620b473e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:620b7010-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:620b99a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:620bc286-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:620beb62-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:620c151a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:620c3df6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:620c6812-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:620c90ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:620cba1a-6b31-11ec-b3df-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:620ce2ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:620d0bd2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92630 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:620d34cc-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:620d5e3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:620d871a-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:620db0e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:620dd9c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:620e03d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4318 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afatinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:620e2cb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:4322 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azilsartan medoxomil is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:620e558c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:4322 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 azilsartan medoxomil targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.38']} DrugCentral uuid:620e7e40-6b31-11ec-b3df-0242ac110002 UniProtKB:P34995 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin E2 receptor EP1 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:620ea79e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5Y4 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin D2 receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.13']} DrugCentral uuid:620ed08e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43115 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin E2 receptor EP3 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:620ef988-6b31-11ec-b3df-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:620f234a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21731 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Thromboxane A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.53']} DrugCentral uuid:620f4c30-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:620f7534-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:620f9e42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:4326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laropiprant is antagonist of GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.52']} DrugCentral uuid:620fc8cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:620ff414-6b31-11ec-b3df-0242ac110002 UniProtKB:P32745 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:62101cf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35346 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.8']} DrugCentral uuid:621045e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30872 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:62106f0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30680 biolink:molecularly_interacts_with DrugCentral:4329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pasireotide is agonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.07']} DrugCentral uuid:6210986a-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bazedoxifene is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.22']} DrugCentral uuid:6210c146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bazedoxifene is modulator of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62117e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQ05 biolink:molecularly_interacts_with DrugCentral:4336 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 amifampridine is blocker of Ion channel (Voltage-gated potassium channel) DrugCentral uuid:62133de0-6b31-11ec-b3df-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:4337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambrisentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.98']} DrugCentral uuid:621367ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ambrisentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.65']} DrugCentral uuid:621390ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4340 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alogliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:6213b9be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:4342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zucapsaicin is opener of Ion channel (Transient receptor potential cation channel subfamily V member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.71']} DrugCentral uuid:6213e290-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.158']} DrugCentral uuid:62140bd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.936']} DrugCentral uuid:621434c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:62145d92-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.726']} DrugCentral uuid:62148678-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.363']} DrugCentral uuid:6214affe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08209 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Enzyme (Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.958']} DrugCentral uuid:6214d8da-6b31-11ec-b3df-0242ac110002 UniProtKB:O43194 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets GPCR (G-protein coupled receptor 39) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.44']} DrugCentral uuid:621501ac-6b31-11ec-b3df-0242ac110002 UniProtKB:A6QR73 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets GPCR (G protein-coupled receptor 39-1b) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:62152a88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPD8 biolink:molecularly_interacts_with DrugCentral:4344 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zinc chloride targets Unclassified (Ubiquitin-conjugating enzyme E2 T) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:62155652-6b31-11ec-b3df-0242ac110002 UniProtKB:P62593 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin targets Enzyme (Beta-lactamase TEM) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:621597ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:621597ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:621597ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:621597ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:621597ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:621597ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:621597ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P24228 biolink:molecularly_interacts_with DrugCentral:4347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzathine benzylpenicillin is inhibitor of Enzyme (Bacterial penicillin-binding protein) DrugCentral uuid:6215fc42-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.5']} DrugCentral uuid:6216251e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Enzyme (Thioredoxin reductase 1, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.398']} DrugCentral uuid:62164e18-6b31-11ec-b3df-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.85']} DrugCentral uuid:621678a2-6b31-11ec-b3df-0242ac110002 UniProtKB:O95264 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Ion channel (5-hydroxytryptamine receptor 3B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.85']} DrugCentral uuid:6216a192-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6N5 biolink:molecularly_interacts_with DrugCentral:4349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aurothioglucose targets Unclassified (Sulfide:quinone oxidoreductase, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.03']} DrugCentral uuid:6216ca8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bilastine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.194']} DrugCentral uuid:6216f3a4-6b31-11ec-b3df-0242ac110002 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:4357 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anidulafungin is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:62171e1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35228 biolink:molecularly_interacts_with DrugCentral:4358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arginine glutamate targets Enzyme (Nitric oxide synthase, inducible) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:6217470a-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:62176ff0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:62179962-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:6217c2ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.54']} DrugCentral uuid:6217ebb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:62181496-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:62183d90-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:62186720-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.23']} DrugCentral uuid:6218901a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.4']} DrugCentral uuid:6218b8f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:6218e1fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:62190cfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:621935ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:62195edc-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:62198826-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:6219b102-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:6219d9de-6b31-11ec-b3df-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:621a02ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:621a2c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:621a5526-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:621a7f10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:621aa80a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib is inhibitor of Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.47']} DrugCentral uuid:621ad1a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:621afa8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:621b2370-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:621b4c42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:621b75a0-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:621b9e7c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:621bc758-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:621bf0ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:621c199c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:621c43cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:621c6cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:621c96f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:621cbfdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:621ce8d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.38']} DrugCentral uuid:621d11bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:621d3afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:621d63ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:621d8cd2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:621db59a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:621ddf20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:621e081a-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:621e3196-6b31-11ec-b3df-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:621e5a5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:621e863c-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:621eaf18-6b31-11ec-b3df-0242ac110002 UniProtKB:P54756 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:621ed7f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:621f0148-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:621f2a38-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:621f5314-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:621f7bf0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:621fa580-6b31-11ec-b3df-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:621fce5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:621ff742-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:62202014-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:62204b02-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.24']} DrugCentral uuid:622073de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:62209cba-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.85']} DrugCentral uuid:6220c596-6b31-11ec-b3df-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:6220eeea-6b31-11ec-b3df-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:622117bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P49761 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:622140ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:62216988-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:622192dc-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.89']} DrugCentral uuid:6221bbc2-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:6221e4a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.48']} DrugCentral uuid:62220f0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:622238f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:622261da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:62228bb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:6222b536-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.33']} DrugCentral uuid:6222de1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:62230824-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:6223313c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:62235a90-6b31-11ec-b3df-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.04']} DrugCentral uuid:6223836c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:6223ac48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96Q40 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:6223d524-6b31-11ec-b3df-0242ac110002 UniProtKB:O14733 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:62240094-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:6224297a-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:62245256-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:62247b3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:6224a4ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:6224cda8-6b31-11ec-b3df-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:6224f67a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:62252050-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:6225494a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:62257226-6b31-11ec-b3df-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.08']} DrugCentral uuid:62259b02-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:6225c4ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:6225edbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:622616ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:62263f94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:62266924-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:62269318-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:6226bbfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:6226e4c6-6b31-11ec-b3df-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:62270e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:622736f6-6b31-11ec-b3df-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:62275fc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:62278930-6b31-11ec-b3df-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:6227b3a6-6b31-11ec-b3df-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:6227dc82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:62280572-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:62282ec6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:622857b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N752 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Casein kinase I isoform alpha-like) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:62288092-6b31-11ec-b3df-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:6228a96e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:6228d2f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:6228fbc6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86UE8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase tousled-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:622924ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:62294d7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:62297916-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:6229a54e-6b31-11ec-b3df-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:6229ce5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:6229f8a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBE8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase NLK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:622a21ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:622a4ac6-6b31-11ec-b3df-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:622a73ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:622a9e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:622ac726-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:622af016-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:622b18e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:622b43ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:622b6d8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:622b9660-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:622bbf3c-6b31-11ec-b3df-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:622be872-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99640 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:622c11da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.29']} DrugCentral uuid:622c3aac-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.48']} DrugCentral uuid:622c6392-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:622c8d22-6b31-11ec-b3df-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.09']} DrugCentral uuid:622cb612-6b31-11ec-b3df-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:622cdeee-6b31-11ec-b3df-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:622d0874-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:622d3150-6b31-11ec-b3df-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:622d5a22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:622d833a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:622dac70-6b31-11ec-b3df-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:622dd538-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NEV4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Myosin-IIIa) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:622dffa4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:622e2894-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:622e521a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:622e7aec-6b31-11ec-b3df-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:622ea4cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:622ecda8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:622ef756-6b31-11ec-b3df-0242ac110002 UniProtKB:P54753 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:622f203c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:622f4922-6b31-11ec-b3df-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:622f71fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:622f9b3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P48729 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Casein kinase I isoform alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:622fc41a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.51']} DrugCentral uuid:622fecec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.49']} DrugCentral uuid:62301686-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:62303f58-6b31-11ec-b3df-0242ac110002 UniProtKB:P16277 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:6230682a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:62309106-6b31-11ec-b3df-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:6230bc76-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:6230e5d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:62310eba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:623137a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:62316144-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:62318a20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:6231b306-6b31-11ec-b3df-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:6231dbd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:62320824-6b31-11ec-b3df-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.32']} DrugCentral uuid:62323240-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.52']} DrugCentral uuid:62325b30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.27']} DrugCentral uuid:62328416-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:6232aef0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:6232d7d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:6233013e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:62332a7e-6b31-11ec-b3df-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:62335364-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:62337c36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:6233a512-6b31-11ec-b3df-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:6233ce98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:6233f77e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:62342050-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:62344940-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:62347410-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:62349d00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:6234c5d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P42679 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Megakaryocyte-associated tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:6234eea4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.11']} DrugCentral uuid:623517d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13233 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:623540ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:6235697e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:623592dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WU08 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase 32A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:6235bbcc-6b31-11ec-b3df-0242ac110002 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:6235e4a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86Y07 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase VRK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:62360d7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:623637b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BQI3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:62366090-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:62368a52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.09']} DrugCentral uuid:6236b428-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NG66 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase Nek11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:6236ddd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:623706a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:62372f8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:62375c48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:62375c48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (NPM/ALK (Nucleophosmin/ALK tyrosine kinase receptor)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:62379686-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:62379686-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Tyrosine-protein kinase ABL) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:6237cf20-6b31-11ec-b3df-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:6237cf20-6b31-11ec-b3df-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bosutinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:623804a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05193 biolink:molecularly_interacts_with DrugCentral:4360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetrimide targets Structural (Dynamin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:62382f60-6b31-11ec-b3df-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:4361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chenodiol is antagonist of GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:62385864-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:4361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chenodiol is agonist of Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:6238812c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:4361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chenodiol is agonist of GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:6238aa80-6b31-11ec-b3df-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:4362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chiniofon targets Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:6238d352-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:4365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vernakalant targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.73']} DrugCentral uuid:6238fc24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vernakalant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.16']} DrugCentral uuid:623924f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZV8 biolink:molecularly_interacts_with DrugCentral:4365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vernakalant targets Ion channel (Potassium voltage-gated channel subfamily D member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:62394e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22460 biolink:molecularly_interacts_with DrugCentral:4365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vernakalant is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.875']} DrugCentral uuid:6239778a-6b31-11ec-b3df-0242ac110002 UniProtKB:P62937 biolink:molecularly_interacts_with DrugCentral:4366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voclosporin is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:6239a070-6b31-11ec-b3df-0242ac110002 UniProtKB:P62937 biolink:molecularly_interacts_with DrugCentral:4366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voclosporin is inhibitor of Enzyme (Peptidyl-prolyl cis-trans isomerase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:6239c92e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium benzoate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:6239f4ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium benzoate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.13']} DrugCentral uuid:623a1ec4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4373 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium benzoate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.61']} DrugCentral uuid:623a47b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcaserin targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.58']} DrugCentral uuid:623a718a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcaserin targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.036']} DrugCentral uuid:623a9b42-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcaserin targets GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.833']} DrugCentral uuid:623ac43c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4374 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorcaserin is agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:623aed2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:623b1658-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UGI6 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:623b3f34-6b31-11ec-b3df-0242ac110002 UniProtKB:P70605 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium targets Ion channel (Small conductance calcium-activated potassium channel protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:623b6838-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92952 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:623b911e-6b31-11ec-b3df-0242ac110002 UniProtKB:P70604 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium is blocker of Ion channel (Small conductance calcium-activated potassium channel protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:623bbae0-6b31-11ec-b3df-0242ac110002 UniProtKB:P29973 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium is blocker of Ion channel (cGMP-gated cation channel alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:623be3a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16280 biolink:molecularly_interacts_with DrugCentral:4376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dequalinium is blocker of Ion channel (Cyclic nucleotide-gated olfactory channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:623c0ca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:4379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 degarelix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:623c35a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desvenlafaxine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.325']} DrugCentral uuid:623c5f18-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desvenlafaxine is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.275']} DrugCentral uuid:623c8808-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 desvenlafaxine targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:623cb102-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dapoxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.95']} DrugCentral uuid:623cd9e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirabegron is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.65']} DrugCentral uuid:623d036e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:623d2c5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:623d5558-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:623d7e5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:623da904-6b31-11ec-b3df-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:623dd1fe-6b31-11ec-b3df-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:623dfac6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:623e255a-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:623e4f08-6b31-11ec-b3df-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:623e77da-6b31-11ec-b3df-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:623ea0d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:623eca8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:623ef746-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:623ef746-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:623f30bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:623f30bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:623f6d34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:623f6d34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:623f6d34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:623f6d34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:623fb9ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:623fee30-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:623fee30-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:623fee30-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:623fee30-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:62403f52-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:62403f52-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:62407bf2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:62407bf2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:62407bf2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:6240bde2-6b31-11ec-b3df-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:4390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline theophyllinate targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:6240e6d2-6b31-11ec-b3df-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.026']} DrugCentral uuid:62410fa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.95']} DrugCentral uuid:62413a10-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:624162e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92887 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Transporter (Canalicular multispecific organic anion transporter 1) DrugCentral uuid:62418768-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:6241b026-6b31-11ec-b3df-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:6241d4e8-6b31-11ec-b3df-0242ac110002 UniProtKB:O15440 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Transporter (Multidrug resistance-associated protein 5) DrugCentral uuid:6241f978-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.582']} DrugCentral uuid:62422236-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.639']} DrugCentral uuid:62424b08-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.321']} DrugCentral uuid:62427470-6b31-11ec-b3df-0242ac110002 UniProtKB:P25025 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (C-X-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.024']} DrugCentral uuid:62429d42-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.029']} DrugCentral uuid:6242c600-6b31-11ec-b3df-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.154']} DrugCentral uuid:6242ef04-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.335']} DrugCentral uuid:62431a6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cisplatin targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.219']} DrugCentral uuid:62434378-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clofenotane targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:62436c22-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clopenthixol targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.77']} DrugCentral uuid:624394f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltrombopag targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.16']} DrugCentral uuid:6243be2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:4399 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eltrombopag is agonist of Membrane receptor (Thrombopoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:6243e81e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:4401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 casopitant targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.53']} DrugCentral uuid:6244110e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:4401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 casopitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:62443a80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7DHH4 biolink:molecularly_interacts_with DrugCentral:4402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceftobiprole medocaril targets Enzyme (MecA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:62446370-6b31-11ec-b3df-0242ac110002 UniProtKB:P61073 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor is partial agonist of GPCR (C-X-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:62448c2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41597 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor targets GPCR (C-C chemokine receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.4']} DrugCentral uuid:6244b4f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P48061 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor targets Cytokine (Stromal cell-derived factor 1) DrugCentral uuid:6244da80-6b31-11ec-b3df-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor is antagonist of GPCR (C-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.19']} DrugCentral uuid:62450348-6b31-11ec-b3df-0242ac110002 UniProtKB:O08565 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor targets GPCR (C-X-C chemokine receptor type 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:62452c10-6b31-11ec-b3df-0242ac110002 UniProtKB:P25106 biolink:molecularly_interacts_with DrugCentral:4410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plerixafor is agonist of GPCR (Atypical chemokine receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:62455668-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.118']} DrugCentral uuid:62457fa8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99720 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.157']} DrugCentral uuid:6245a8a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.886']} DrugCentral uuid:6245d174-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.308']} DrugCentral uuid:6245fa46-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.977']} DrugCentral uuid:624624bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.915']} DrugCentral uuid:62464dde-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.677']} DrugCentral uuid:62467700-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:62469fdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.085']} DrugCentral uuid:6246cb2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.478']} DrugCentral uuid:6246f41e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.604']} DrugCentral uuid:62471d0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.262']} DrugCentral uuid:62474630-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.559']} DrugCentral uuid:62476f20-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.126']} DrugCentral uuid:62479810-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.131']} DrugCentral uuid:6247c0f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.781']} DrugCentral uuid:6247ea86-6b31-11ec-b3df-0242ac110002 UniProtKB:P15823 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.065']} DrugCentral uuid:62481358-6b31-11ec-b3df-0242ac110002 UniProtKB:P70580 biolink:molecularly_interacts_with DrugCentral:4411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexchlorpheniramine targets Membrane receptor (Membrane-associated progesterone receptor component 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.931']} DrugCentral uuid:62483c48-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:4412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diamorphine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:62486506-6b31-11ec-b3df-0242ac110002 UniProtKB:P18901 biolink:molecularly_interacts_with DrugCentral:4412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diamorphine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.62']} DrugCentral uuid:62488fe0-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:4412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diamorphine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.44']} DrugCentral uuid:6248b93e-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dibutylphthalate is activator of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:6248e224-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:4420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocryptine is agonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:62490b00-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:4420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocryptine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.5']} DrugCentral uuid:62493558-6b31-11ec-b3df-0242ac110002 UniProtKB:P32304 biolink:molecularly_interacts_with DrugCentral:4420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dihydroergocryptine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:62495e34-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:62498710-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.018']} DrugCentral uuid:6249b000-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.652']} DrugCentral uuid:6249d972-6b31-11ec-b3df-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.092']} DrugCentral uuid:624a024e-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.604']} DrugCentral uuid:624a2b20-6b31-11ec-b3df-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:4425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 colistin targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.775']} DrugCentral uuid:624a54ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:624a7e18-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:624aa8ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.57']} DrugCentral uuid:624ad1b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:624afae6-6b31-11ec-b3df-0242ac110002 UniProtKB:P05186 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Alkaline phosphatase, tissue-nonspecific isozyme) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.09']} DrugCentral uuid:624b23ae-6b31-11ec-b3df-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:624b4cee-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.15']} DrugCentral uuid:624b75b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.17']} DrugCentral uuid:624b9f32-6b31-11ec-b3df-0242ac110002 UniProtKB:E1BN64 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Uncharacterized protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.11']} DrugCentral uuid:624bc80e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28647 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.07']} DrugCentral uuid:624bf0d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P28190 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.42']} DrugCentral uuid:624c19b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P47745 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.01']} DrugCentral uuid:624c47d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:624c47d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.88']} DrugCentral uuid:624c8096-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:624c8096-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14432 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 3) DrugCentral uuid:624cbb1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:624cbb1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:624cbb1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:624cbb1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:624d098a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29276 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine A2b receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.82']} DrugCentral uuid:624d3dec-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:624d3dec-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:624d3dec-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:624d3dec-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.7']} DrugCentral uuid:624d8f68-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:624d8f68-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline is antagonist of GPCR (Adenosine A2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.85']} DrugCentral uuid:624dcc26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:624dcc26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:624dcc26-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01061 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets Enzyme (Heart phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:624e0dc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P46616 biolink:molecularly_interacts_with DrugCentral:4426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bufylline targets GPCR (Adenosine A2a receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:624e36d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30988 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Calcitonin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:624e63ac-6b31-11ec-b3df-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.53']} DrugCentral uuid:624e63ac-6b31-11ec-b3df-0242ac110002 UniProtKB:O60894 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.53']} DrugCentral uuid:624e9cdc-6b31-11ec-b3df-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.082']} DrugCentral uuid:624e9cdc-6b31-11ec-b3df-0242ac110002 UniProtKB:O60895 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.082']} DrugCentral uuid:624ed59e-6b31-11ec-b3df-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.706']} DrugCentral uuid:624ed59e-6b31-11ec-b3df-0242ac110002 UniProtKB:O60896 biolink:molecularly_interacts_with DrugCentral:4427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 calcitonin human is agonist of GPCR (Amylin receptor AMY3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.706']} DrugCentral uuid:624f0a8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prednisolone sodium phosphate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:624f2f44-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.179']} DrugCentral uuid:624f58c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P04083 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Cytosolic other (Annexin A1) DrugCentral uuid:624f7d3c-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:624fa5f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.599']} DrugCentral uuid:624fcf30-6b31-11ec-b3df-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:624ff91a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.818']} DrugCentral uuid:62502408-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:62504cbc-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.46']} DrugCentral uuid:62507688-6b31-11ec-b3df-0242ac110002 UniProtKB:P20815 biolink:molecularly_interacts_with DrugCentral:4452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clobetasol propionate targets Enzyme (Cytochrome P450 3A5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:62509f50-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone cypionate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:6250c3ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4456 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone succinate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:6250e870-6b31-11ec-b3df-0242ac110002 UniProtKB:P06537 biolink:molecularly_interacts_with DrugCentral:4456 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone succinate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:6251120a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AC13 biolink:molecularly_interacts_with DrugCentral:4458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfisoxazole acetyl is inhibitor of Enzyme (Dihydropteroate synthase) DrugCentral uuid:62513686-6b31-11ec-b3df-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfisoxazole acetyl targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:62515f76-6b31-11ec-b3df-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:4458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfisoxazole acetyl targets GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:6251883e-6b31-11ec-b3df-0242ac110002 UniProtKB:P26684 biolink:molecularly_interacts_with DrugCentral:4458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sulfisoxazole acetyl targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.11']} DrugCentral uuid:6251b26e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99873 biolink:molecularly_interacts_with DrugCentral:4466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eosin targets Enzyme (Protein arginine N-methyltransferase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:6251dbae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5VLE3 biolink:molecularly_interacts_with DrugCentral:4466 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eosin targets Enzyme (RmtA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:62521b32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:62521b32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:62521b32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:62521b32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:62521b32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:62521b32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:62521b32-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4468 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esketamine is antagonist of Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.161']} DrugCentral uuid:62528c48-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:4470 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosaprepitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:6252b51a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trisodium citrate dihydrate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:6252ddf6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4474 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trisodium citrate dihydrate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:62530772-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium citrate targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:62533062-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4477 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium citrate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:6253595c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19111 biolink:molecularly_interacts_with DrugCentral:4480 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 potassium phosphate, monobasic targets Enzyme (Intestinal alkaline phosphatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:62538396-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.6']} DrugCentral uuid:6253b910-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:6253b910-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:6253b910-6b31-11ec-b3df-0242ac110002 UniProtKB:P22909 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.69']} DrugCentral uuid:625406b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:625406b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:625406b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:62544f92-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:62544f92-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:62544f92-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4482 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corbadrine is agonist of GPCR (Adrenergic receptor alpha-2) DrugCentral uuid:625488cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:6254b194-6b31-11ec-b3df-0242ac110002 UniProtKB:P07858 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Cathepsin B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:6254db06-6b31-11ec-b3df-0242ac110002 UniProtKB:P28062 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:625503ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.84']} DrugCentral uuid:62552c96-6b31-11ec-b3df-0242ac110002 UniProtKB:P49721 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.69']} DrugCentral uuid:62555694-6b31-11ec-b3df-0242ac110002 UniProtKB:P78417 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Unclassified (Glutathione S-transferase omega-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:6255816e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.84']} DrugCentral uuid:6255ab8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28065 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:6255d452-6b31-11ec-b3df-0242ac110002 UniProtKB:P40306 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Enzyme (Proteasome subunit beta type-10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:6255fd9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.04']} DrugCentral uuid:6256270e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:4483 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 carfilzomib is inhibitor of Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:62564fb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:62567894-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:6256a238-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.15']} DrugCentral uuid:6256cb1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:6256f3fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4484 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aclidinium bromide targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.8']} DrugCentral uuid:62571ce0-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4485 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflorasone diacetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.536']} DrugCentral uuid:625747a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4485 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diflorasone diacetate targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:62577096-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4493 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alclometasone dipropionate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:62579530-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol decanoate is inverse agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.34']} DrugCentral uuid:6257be0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol decanoate targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:6257e738-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:4496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol decanoate targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.24']} DrugCentral uuid:6258101e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50130 biolink:molecularly_interacts_with DrugCentral:4496 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 haloperidol decanoate targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.85']} DrugCentral uuid:625838fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4497 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estradiol acetate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:62585e16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4498 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone palmitate targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:62588710-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4498 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone palmitate is antagonist of GPCR (D(2) dopamine receptor) DrugCentral uuid:6258abaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4498 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paliperidone palmitate is antagonist of GPCR (5-hydroxytryptamine receptor 2A) DrugCentral uuid:6258d026-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.921']} DrugCentral uuid:6258f98e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.41']} DrugCentral uuid:625922ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.497']} DrugCentral uuid:62594b78-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets GPCR (Alpha-1B adrenergic receptor) DrugCentral uuid:62596ff4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets Enzyme (Cytochrome P450 1A2) DrugCentral uuid:62599452-6b31-11ec-b3df-0242ac110002 UniProtKB:P33261 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets Enzyme (Cytochrome P450 2C19) DrugCentral uuid:6259b932-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:4501 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 armodafinil targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.49']} DrugCentral uuid:6259e236-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4504 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone valerate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:625a06d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline fenofibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.46']} DrugCentral uuid:625a2fb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P12104 biolink:molecularly_interacts_with DrugCentral:4505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline fenofibrate targets Cytosolic other (Fatty acid-binding protein, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:625a5950-6b31-11ec-b3df-0242ac110002 UniProtKB:P02692 biolink:molecularly_interacts_with DrugCentral:4505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline fenofibrate targets Unclassified (Fatty acid-binding protein, liver) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:625a8240-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:4505 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choline fenofibrate targets Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:625aab26-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4507 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halcinonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.135']} DrugCentral uuid:625ad542-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4507 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halcinonide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.229']} DrugCentral uuid:625afe64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q690N0 biolink:molecularly_interacts_with DrugCentral:4507 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 halcinonide targets Transcription factor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.917']} DrugCentral uuid:625b2754-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:4508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racepinefrine is agonist of GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:625b5120-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:4508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racepinefrine is agonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6']} DrugCentral uuid:625b7a60-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:4508 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 racepinefrine is agonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:625ba7a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium citrate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:625ba7a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium citrate is inhibitor of Kinase (Glycogen synthase kinase-3) DrugCentral uuid:625bd69a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29218 biolink:molecularly_interacts_with DrugCentral:4512 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lithium citrate is inhibitor of Enzyme (Inositol-1(or 4)-monophosphatase 1) DrugCentral uuid:625bfb2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03431 biolink:molecularly_interacts_with DrugCentral:4514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:625c24a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P49190 biolink:molecularly_interacts_with DrugCentral:4514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:625c4eb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P70555 biolink:molecularly_interacts_with DrugCentral:4514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:625c7794-6b31-11ec-b3df-0242ac110002 UniProtKB:P25961 biolink:molecularly_interacts_with DrugCentral:4514 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriparatide is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:625ca070-6b31-11ec-b3df-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4516 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracosactide targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.19']} DrugCentral uuid:625cca96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:4516 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tetracosactide is agonist of GPCR (Adrenocorticotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.268']} DrugCentral uuid:625cf35e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) DrugCentral uuid:625d17e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.92']} DrugCentral uuid:625d411a-6b31-11ec-b3df-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Secreted (Hemoglobin subunit alpha) DrugCentral uuid:625d65b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92953 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine is blocker of Ion channel (Potassium voltage-gated channel subfamily B member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:625d8e90-6b31-11ec-b3df-0242ac110002 UniProtKB:O15245 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Transporter (Solute carrier family 22 member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:625dbf28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:625dbf28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:625dbf28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY46 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:625e00b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7RTT9 biolink:molecularly_interacts_with DrugCentral:4523 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quinine is inhibitor of Transporter (Equilibrative nucleoside transporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.57']} DrugCentral uuid:625e29a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:4536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbendazole targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.496']} DrugCentral uuid:625e5262-6b31-11ec-b3df-0242ac110002 UniProtKB:P10424 biolink:molecularly_interacts_with DrugCentral:4536 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fenbendazole targets Enzyme (Beta-lactamase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.222']} DrugCentral uuid:625e7c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.12']} DrugCentral uuid:625ea5be-6b31-11ec-b3df-0242ac110002 UniProtKB:P08235 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Nuclear hormone receptor (Mineralocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.83']} DrugCentral uuid:625eceae-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:625ef870-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:625f220a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06536 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Transcription factor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:625f4ae6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:4554 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluticasone furoate targets Nuclear hormone receptor (Progesterone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.68']} DrugCentral uuid:625f73c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.24']} DrugCentral uuid:625f9cb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.89']} DrugCentral uuid:625fc64c-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:625fef32-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:62602394-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:62602394-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:62602394-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:62602394-6b31-11ec-b3df-0242ac110002 UniProtKB:P30940 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Serotonin 1 (5-HT1) receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:62607b6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:62607b6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:62607b6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43140 biolink:molecularly_interacts_with DrugCentral:4562 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gepirone targets GPCR (Adrenergic receptor alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:6260c024-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium oxybate is agonist of GPCR (GABA-B receptor) DrugCentral uuid:6260c024-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium oxybate is agonist of GPCR (GABA-B receptor) DrugCentral uuid:6260ef72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6RY99 biolink:molecularly_interacts_with DrugCentral:4566 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium oxybate targets Unclassified (Gamma-hydroxybutyrate receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:6261184e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4568 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrochloric acid targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.05']} DrugCentral uuid:62614148-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4569 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 hydrocortisone probutate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:62616664-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4573 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.11']} DrugCentral uuid:62618fe0-6b31-11ec-b3df-0242ac110002 UniProtKB:P16184 biolink:molecularly_interacts_with DrugCentral:4573 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.62']} DrugCentral uuid:6261b8a8-6b31-11ec-b3df-0242ac110002 UniProtKB:B0BL08 biolink:molecularly_interacts_with DrugCentral:4573 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:6261e198-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A017 biolink:molecularly_interacts_with DrugCentral:4573 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iclaprim targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.1']} DrugCentral uuid:626215f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:626215f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:626215f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:626215f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4586 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomethadone targets GPCR (Opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:62626730-6b31-11ec-b3df-0242ac110002 UniProtKB:O43526 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:6262900c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NR82 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:6262b8fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P56696 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is blocker of Ion channel (Potassium voltage-gated channel subfamily KQT member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:6262e250-6b31-11ec-b3df-0242ac110002 UniProtKB:O88944 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is inhibitor of Ion channel (Potassium voltage-gated channel subfamily KQT member 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:62630b2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P97414 biolink:molecularly_interacts_with DrugCentral:4588 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linopirdine is inhibitor of Ion channel (Potassium voltage-gated channel subfamily KQT member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:626333ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Transporter (Multidrug resistance-associated protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:62635d66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16678 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Enzyme (Cytochrome P450 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.54']} DrugCentral uuid:6263862e-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:6263aee2-6b31-11ec-b3df-0242ac110002 UniProtKB:O60341 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Enzyme (Lysine-specific histone demethylase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.55']} DrugCentral uuid:6263d7e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFU5 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Kinase (Inositol polyphosphate multikinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.14']} DrugCentral uuid:62640252-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHH9 biolink:molecularly_interacts_with DrugCentral:4601 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diosmetin targets Kinase (Inositol hexakisphosphate kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:62642e94-6b31-11ec-b3df-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:4605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tonzonium targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:6264586a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63470 biolink:molecularly_interacts_with DrugCentral:4605 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tonzonium targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.03']} DrugCentral uuid:62648128-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4606 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clocortolone pivalate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:6264a608-6b31-11ec-b3df-0242ac110002 UniProtKB:P18031 biolink:molecularly_interacts_with DrugCentral:4608 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trypan blue targets Enzyme (Tyrosine-protein phosphatase non-receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:6264cee4-6b31-11ec-b3df-0242ac110002 UniProtKB:P25044 biolink:molecularly_interacts_with DrugCentral:4608 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trypan blue targets Enzyme (Tyrosine-protein phosphatase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.13']} DrugCentral uuid:6264f7c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4609 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 testosterone enantate is agonist of Nuclear hormone receptor (Androgen receptor) DrugCentral uuid:62651c46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:626545d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:62656ea8-6b31-11ec-b3df-0242ac110002 UniProtKB:P15090 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Cytosolic other (Fatty acid-binding protein, adipocyte) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.1']} DrugCentral uuid:62659798-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:6265c088-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:4611 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 stearic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.44']} DrugCentral uuid:6265eae0-6b31-11ec-b3df-0242ac110002 UniProtKB:P27471 biolink:molecularly_interacts_with DrugCentral:4615 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 N-Acetylglucosamine targets Unclassified (Killer cell lectin-like receptor subfamily B member 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:626614de-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.55']} DrugCentral uuid:62663dce-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:626666f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.65']} DrugCentral uuid:62668fe0-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.05']} DrugCentral uuid:6266b8da-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:4616 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylnaltrexone targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:6266e260-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.4']} DrugCentral uuid:62670be6-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:626734d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.1']} DrugCentral uuid:62675dbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:626786ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P05413 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Cytosolic other (Fatty acid-binding protein, heart) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.56']} DrugCentral uuid:6267b186-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:6267dac6-6b31-11ec-b3df-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:62680384-6b31-11ec-b3df-0242ac110002 UniProtKB:P13726 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Membrane receptor (Tissue factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:62682c56-6b31-11ec-b3df-0242ac110002 UniProtKB:P79208 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.92']} DrugCentral uuid:6268556e-6b31-11ec-b3df-0242ac110002 UniProtKB:O62664 biolink:molecularly_interacts_with DrugCentral:4618 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linolenic acid targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.03']} DrugCentral uuid:62687e5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:4619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenol targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:6268a74e-6b31-11ec-b3df-0242ac110002 UniProtKB:P40763 biolink:molecularly_interacts_with DrugCentral:4619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenol targets Transcription factor (Signal transducer and activator of transcription 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:6268d16a-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:4619 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomenol targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:6268fac8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04818 biolink:molecularly_interacts_with DrugCentral:4621 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomefolic acid targets Enzyme (Thymidylate synthase) DrugCentral uuid:62691f6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23897 biolink:molecularly_interacts_with DrugCentral:4622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linaclotide is agonist of Enzyme (Heat-stable enterotoxin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.38']} DrugCentral uuid:6269487a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25092 biolink:molecularly_interacts_with DrugCentral:4622 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 linaclotide is agonist of Enzyme (Heat-stable enterotoxin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.907']} DrugCentral uuid:6269868c-6b31-11ec-b3df-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:6269868c-6b31-11ec-b3df-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:6269868c-6b31-11ec-b3df-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:6269868c-6b31-11ec-b3df-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:6269868c-6b31-11ec-b3df-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:6269868c-6b31-11ec-b3df-0242ac110002 UniProtKB:E0VP62 biolink:molecularly_interacts_with DrugCentral:4623 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 spinosad is agonist of Ion channel (Nicotinic acetylcholine receptor) DrugCentral uuid:6269e046-6b31-11ec-b3df-0242ac110002 UniProtKB:P15121 biolink:molecularly_interacts_with DrugCentral:4624 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenylacetic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.02']} DrugCentral uuid:626a08fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:626a3258-6b31-11ec-b3df-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:626a5b3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:626a842e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:626aada0-6b31-11ec-b3df-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:626ad6b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63931 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:626b039a-6b31-11ec-b3df-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:626b039a-6b31-11ec-b3df-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4627 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sincalide targets GPCR (Cholecystokinin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:626b389c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:4628 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enzalutamide is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.31']} DrugCentral uuid:626b6420-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:4628 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enzalutamide targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.53']} DrugCentral uuid:626b8d06-6b31-11ec-b3df-0242ac110002 UniProtKB:P14324 biolink:molecularly_interacts_with DrugCentral:4630 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium pyrophosphate targets Enzyme (Farnesyl pyrophosphate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.53']} DrugCentral uuid:626bb5ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P16066 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside targets Enzyme (Atrial natriuretic peptide receptor 1) DrugCentral uuid:626be634-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:626be634-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:626be634-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:626be634-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4631 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nitroprusside is activator of Enzyme (Soluble guanylate cyclase) DrugCentral uuid:626c29d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trabectedin targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:626c52ae-6b31-11ec-b3df-0242ac110002 UniProtKB:O54915 biolink:molecularly_interacts_with DrugCentral:4633 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trabectedin is antagonist of Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:626c7c2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02127 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide is inhibitor of Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.52']} DrugCentral uuid:626ca5c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00374 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide targets Enzyme (Dihydrofolate reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:626cce8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63707 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:626cf75e-6b31-11ec-b3df-0242ac110002 UniProtKB:O35435 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide targets Enzyme (Dihydroorotate dehydrogenase (quinone), mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.16']} DrugCentral uuid:626d2152-6b31-11ec-b3df-0242ac110002 UniProtKB:Q54A96 biolink:molecularly_interacts_with DrugCentral:4634 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teriflunomide targets Enzyme (Dihydroorotate dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.66']} DrugCentral uuid:626d4a74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8BGY9 biolink:molecularly_interacts_with DrugCentral:4635 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 Choline C-11 targets Transporter (High affinity choline transporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.17']} DrugCentral uuid:626d742c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00811 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:626d9cfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:626dc602-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99895 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Enzyme (Chymotrypsin C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:626deec0-6b31-11ec-b3df-0242ac110002 UniProtKB:P16278 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:626e179c-6b31-11ec-b3df-0242ac110002 UniProtKB:O06446 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Unclassified (Protein translocase subunit SecA 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:626e4078-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2FUW6 biolink:molecularly_interacts_with DrugCentral:4637 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rose bengal targets Unclassified (Protein translocase subunit SecA 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.7']} DrugCentral uuid:626e6a58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8HZ64 biolink:molecularly_interacts_with DrugCentral:4641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levmetamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:626e9456-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y9 biolink:molecularly_interacts_with DrugCentral:4641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levmetamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.63']} DrugCentral uuid:626ebd1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923Y8 biolink:molecularly_interacts_with DrugCentral:4641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levmetamfetamine targets GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:626ee604-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RJ0 biolink:molecularly_interacts_with DrugCentral:4641 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levmetamfetamine is agonist of GPCR (Trace amine-associated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:626f120a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:626f3e56-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:626f689a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid targets Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.52']} DrugCentral uuid:626f91da-6b31-11ec-b3df-0242ac110002 UniProtKB:O14842 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid targets GPCR (Free fatty acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:626fba98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NQS5 biolink:molecularly_interacts_with DrugCentral:4642 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dodecanoic acid is agonist of GPCR (G-protein coupled receptor 84) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:626fe360-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4647 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluorometholone acetate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.347']} DrugCentral uuid:62700c28-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:4648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eugenol targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:62703590-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:4648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eugenol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:62705e62-6b31-11ec-b3df-0242ac110002 UniProtKB:P09917 biolink:molecularly_interacts_with DrugCentral:4648 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eugenol targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.58']} DrugCentral uuid:6270873e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23415 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Ion channel (Glycine receptor subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:6270b006-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:6270da2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.21']} DrugCentral uuid:627102fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:62712bda-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:62715664-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:62717f90-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:6271a88a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:6271d152-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:6271fa42-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:627223d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34913 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib is inhibitor of Enzyme (Bifunctional epoxide hydrolase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:62724c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:62727558-6b31-11ec-b3df-0242ac110002 UniProtKB:P35917 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:62729f38-6b31-11ec-b3df-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:6272cae4-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:6272f3ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:62731c6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:62734578-6b31-11ec-b3df-0242ac110002 UniProtKB:P35917 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:62736e36-6b31-11ec-b3df-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:62739726-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.09']} DrugCentral uuid:6273bfe4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4654 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 regorafenib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:6273e960-6b31-11ec-b3df-0242ac110002 UniProtKB:Q17ST2 biolink:molecularly_interacts_with DrugCentral:4655 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tedisamil is blocker of Ion channel (Potassium voltage-gated channel subfamily A member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.7']} DrugCentral uuid:62741246-6b31-11ec-b3df-0242ac110002 UniProtKB:O75762 biolink:molecularly_interacts_with DrugCentral:4659 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metamizole is blocker of Ion channel (Transient receptor potential cation channel subfamily A member 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.041']} DrugCentral uuid:62743b0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10980 biolink:molecularly_interacts_with DrugCentral:4660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.57']} DrugCentral uuid:627463d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08482 biolink:molecularly_interacts_with DrugCentral:4660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.6']} DrugCentral uuid:62748fbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08483 biolink:molecularly_interacts_with DrugCentral:4660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.59']} DrugCentral uuid:6274b944-6b31-11ec-b3df-0242ac110002 UniProtKB:P16395 biolink:molecularly_interacts_with DrugCentral:4660 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methylatropine targets GPCR (Muscarinic acetylcholine receptor DM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:6274e220-6b31-11ec-b3df-0242ac110002 UniProtKB:P23141 biolink:molecularly_interacts_with DrugCentral:4663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoin targets Enzyme (Liver carboxylesterase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:62750af2-6b31-11ec-b3df-0242ac110002 UniProtKB:O00748 biolink:molecularly_interacts_with DrugCentral:4663 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoin targets Enzyme (Cocaine esterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.65']} DrugCentral uuid:62753518-6b31-11ec-b3df-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:4664 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoic acid targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.86']} DrugCentral uuid:62755e12-6b31-11ec-b3df-0242ac110002 UniProtKB:P14920 biolink:molecularly_interacts_with DrugCentral:4664 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoic acid targets Enzyme (D-amino-acid oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:6275884c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XQN6 biolink:molecularly_interacts_with DrugCentral:4664 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benzoic acid targets Enzyme (Nicotinate phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.72']} DrugCentral uuid:6275b1c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.932']} DrugCentral uuid:6275dac2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.776']} DrugCentral uuid:627603a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.866']} DrugCentral uuid:62762c98-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.779']} DrugCentral uuid:62765678-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate targets GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.248']} DrugCentral uuid:62767f72-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4667 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betamethasone phosphate is agonist of Nuclear hormone receptor (Glucocorticoid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.428']} DrugCentral uuid:6276a862-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2I1 biolink:molecularly_interacts_with DrugCentral:4671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metizoline targets Membrane receptor (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.2']} DrugCentral uuid:6276d1b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:4671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metizoline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:6276fad8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21396 biolink:molecularly_interacts_with DrugCentral:4671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metizoline targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.86']} DrugCentral uuid:627723b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4G017 biolink:molecularly_interacts_with DrugCentral:4671 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metizoline targets Unclassified (Nischarin) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:62774cb8-6b31-11ec-b3df-0242ac110002 UniProtKB:O43613 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.6']} DrugCentral uuid:62777580-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.14']} DrugCentral uuid:62779ec0-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.13']} DrugCentral uuid:6277c760-6b31-11ec-b3df-0242ac110002 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.833']} DrugCentral uuid:6277f028-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:627818dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:627845a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P42866 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.37']} DrugCentral uuid:62786ed6-6b31-11ec-b3df-0242ac110002 UniProtKB:P97266 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:627897b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P32300 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:6278c0e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.43']} DrugCentral uuid:6278e9d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:627912d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:62793c76-6b31-11ec-b3df-0242ac110002 UniProtKB:P33534 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:62796606-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:62798eb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.26']} DrugCentral uuid:6279b76e-6b31-11ec-b3df-0242ac110002 UniProtKB:P34975 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine targets GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:6279e036-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:4673 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nalfurafine is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:627a0c1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4676 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obidoxime targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.67']} DrugCentral uuid:627a35b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XYC7 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:627a5e6c-6b31-11ec-b3df-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:627a8734-6b31-11ec-b3df-0242ac110002 UniProtKB:A5H660 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat targets Unclassified (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:627ab09c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:627ad978-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.19']} DrugCentral uuid:627b0272-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:627b2c0c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.96']} DrugCentral uuid:627b5506-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.15']} DrugCentral uuid:627b7df6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:627ba70e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:627bd198-6b31-11ec-b3df-0242ac110002 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.22']} DrugCentral uuid:627bfaec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.92']} DrugCentral uuid:627c23dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:627c4eb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4682 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panobinostat is inhibitor of Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.46']} DrugCentral uuid:627c77ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:627ca0a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:627cc94a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:627cf208-6b31-11ec-b3df-0242ac110002 UniProtKB:P06276 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:627d1b7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:627d4528-6b31-11ec-b3df-0242ac110002 UniProtKB:P21836 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:627d6ddc-6b31-11ec-b3df-0242ac110002 UniProtKB:P47746 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:627d96a4-6b31-11ec-b3df-0242ac110002 UniProtKB:O35678 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Monoglyceride lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:627dc0ca-6b31-11ec-b3df-0242ac110002 UniProtKB:O08914 biolink:molecularly_interacts_with DrugCentral:4683 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 paraoxon targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.27']} DrugCentral uuid:627df52c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:627df52c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:627df52c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:627df52c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48058 biolink:molecularly_interacts_with DrugCentral:4684 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 perampanel is antagonist of Ion channel (Glutamate receptor ionotropic AMPA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:627e423e-6b31-11ec-b3df-0242ac110002 UniProtKB:O75469 biolink:molecularly_interacts_with DrugCentral:4690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pleconaril targets Nuclear hormone receptor (Nuclear receptor subfamily 1 group I member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:627e6af2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4U254 biolink:molecularly_interacts_with DrugCentral:4690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pleconaril targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:627e93ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7T664 biolink:molecularly_interacts_with DrugCentral:4690 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pleconaril targets Unclassified (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:627ebc82-6b31-11ec-b3df-0242ac110002 UniProtKB:P00797 biolink:molecularly_interacts_with DrugCentral:4696 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remikiren is inhibitor of Enzyme (Renin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:627ee5fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:627f0eee-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:627f37d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.75']} DrugCentral uuid:627f60a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5']} DrugCentral uuid:627f8ba8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.93']} DrugCentral uuid:627fb48e-6b31-11ec-b3df-0242ac110002 UniProtKB:B0FL73 biolink:molecularly_interacts_with DrugCentral:4702 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esatenolol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:627fdd92-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4704 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 semustine targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.744']} DrugCentral uuid:62800678-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.074']} DrugCentral uuid:62803044-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16881 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets Enzyme (Thioredoxin reductase 1, cytoplasmic) DrugCentral uuid:628054de-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.624']} DrugCentral uuid:62807d92-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.091']} DrugCentral uuid:6280a70e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07711 biolink:molecularly_interacts_with DrugCentral:4706 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium aurothiomalate targets Enzyme (Cathepsin L1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:6280cfea-6b31-11ec-b3df-0242ac110002 UniProtKB:P32241 biolink:molecularly_interacts_with DrugCentral:4710 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatorelin is agonist of GPCR (Vasoactive intestinal polypeptide receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:6280f9ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:62812288-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:62814c9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:62817562-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:62819e34-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:6281c71a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:6281f050-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:628219cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.17']} DrugCentral uuid:628242bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:62826ba2-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:62829514-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:6282bde6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:6282e7f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:628310de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:62833d20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:62836674-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:62838f64-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:6283b8b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:6283e19e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:62840a70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.35']} DrugCentral uuid:6284334c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:62845ce6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:628485b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:6284ae9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:6284d784-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.36']} DrugCentral uuid:62850290-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:62852b6c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:62855452-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:62857d2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:6285a66e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:6285cf36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:6285f812-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62137 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:628620da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:6286a500-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62120 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:6286cfc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:6286fd66-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:6286fd66-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:62873ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:62873ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:62873ac4-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK1/JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.12']} DrugCentral uuid:6287802e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:6287802e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:6287b530-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63272 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:6287e1fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.391']} DrugCentral uuid:6287e1fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK2/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.391']} DrugCentral uuid:62881c78-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.252']} DrugCentral uuid:62881c78-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4713 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofacitinib is inhibitor of Kinase (JAK3/JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.252']} DrugCentral uuid:6288513e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.907']} DrugCentral uuid:62887a06-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.65']} DrugCentral uuid:6288a490-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:6288cf24-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:6288f7e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:628920a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.95']} DrugCentral uuid:628949e0-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:62897474-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:62899d46-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:6289c622-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.337']} DrugCentral uuid:6289efb2-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.947']} DrugCentral uuid:628a18a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.284']} DrugCentral uuid:628a4192-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.456']} DrugCentral uuid:628a6b2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.845']} DrugCentral uuid:628a9714-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4715 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabozantinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.886']} DrugCentral uuid:628ac0b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:628ae9d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.432']} DrugCentral uuid:628b12fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.903']} DrugCentral uuid:628b3bce-6b31-11ec-b3df-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Breakpoint cluster region protein) DrugCentral uuid:628b6040-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:628b88f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:628bb266-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:628bdb42-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.824']} DrugCentral uuid:628c041e-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.959']} DrugCentral uuid:628c2d22-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.03']} DrugCentral uuid:628c5734-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.268']} DrugCentral uuid:628c801a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:628ca9dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.658']} DrugCentral uuid:628cd2ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:628cfc5c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:628d2560-6b31-11ec-b3df-0242ac110002 UniProtKB:P00523 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.05']} DrugCentral uuid:628d4e3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:628d77ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P49336 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Cyclin-dependent kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.17']} DrugCentral uuid:628da09e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:628dc966-6b31-11ec-b3df-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:628df5ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:628df5ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P11274 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib targets Kinase (Bcr/Abl fusion protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:628e2d66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4716 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponatinib is inhibitor of Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:628e57dc-6b31-11ec-b3df-0242ac110002 UniProtKB:O95838 biolink:molecularly_interacts_with DrugCentral:4718 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teduglutide is agonist of GPCR (Glucagon-like peptide 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:628e80cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z0W0 biolink:molecularly_interacts_with DrugCentral:4718 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teduglutide targets GPCR (Glucagon-like peptide 2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.1']} DrugCentral uuid:628ea980-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Transporter (Multidrug resistance protein 1) DrugCentral uuid:628ece56-6b31-11ec-b3df-0242ac110002 UniProtKB:P11388 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Enzyme (DNA topoisomerase 2-alpha) DrugCentral uuid:628ef2be-6b31-11ec-b3df-0242ac110002 UniProtKB:P33527 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Transporter (Multidrug resistance-associated protein 1) DrugCentral uuid:628f1726-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Transporter (ATP-binding cassette sub-family G member 2) DrugCentral uuid:628f3b84-6b31-11ec-b3df-0242ac110002 UniProtKB:O95255 biolink:molecularly_interacts_with DrugCentral:4719 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daunorubicinol targets Transporter (Multidrug resistance-associated protein 6) DrugCentral uuid:628f60c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P55157 biolink:molecularly_interacts_with DrugCentral:4721 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lomitapide is inhibitor of Cytosolic other (Microsomal triglyceride transfer protein large subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.097']} DrugCentral uuid:628f89a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:4723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 succinimide targets Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.58']} DrugCentral uuid:628fb28a-6b31-11ec-b3df-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:4723 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 succinimide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.37']} DrugCentral uuid:628fdb70-6b31-11ec-b3df-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:4727 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tacalcitol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.5']} DrugCentral uuid:629006b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.573']} DrugCentral uuid:629030ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.26']} DrugCentral uuid:6290596a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.155']} DrugCentral uuid:62908228-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6']} DrugCentral uuid:6290ac44-6b31-11ec-b3df-0242ac110002 UniProtKB:P12527 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Arachidonate 5-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:6290d516-6b31-11ec-b3df-0242ac110002 UniProtKB:O97554 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:6290fdf2-6b31-11ec-b3df-0242ac110002 UniProtKB:O02768 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:62912b56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:62912b56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap targets Enzyme (Cyclooxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:62916030-6b31-11ec-b3df-0242ac110002 UniProtKB:P48050 biolink:molecularly_interacts_with DrugCentral:4728 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenidap is activator of Ion channel (Inward rectifier potassium channel 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6291c304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ES14 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside targets Ion channel (GABA-A receptor; anion channel) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6292aa44-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:6292aa44-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:6292aa44-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.699']} DrugCentral uuid:6292f3f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:6292f3f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:6292f3f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.886']} DrugCentral uuid:62933ce8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.824']} DrugCentral uuid:62933ce8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.824']} DrugCentral uuid:62933ce8-6b31-11ec-b3df-0242ac110002 UniProtKB:P18507 biolink:molecularly_interacts_with DrugCentral:4731 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiocolchicoside is negative modulator of Ion channel (GABA A receptor alpha-1/beta-1/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.824']} DrugCentral uuid:62937d70-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioctic acid targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:6293ab74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:4732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioctic acid targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:6293ab74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBT2 biolink:molecularly_interacts_with DrugCentral:4732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioctic acid targets Enzyme (SUMO-activating enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.32']} DrugCentral uuid:6293e03a-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WMN3 biolink:molecularly_interacts_with DrugCentral:4732 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thioctic acid targets Enzyme (Bifunctional protein GlmU) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.41']} DrugCentral uuid:6294090c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.699']} DrugCentral uuid:62943238-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.971']} DrugCentral uuid:62945b0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.035']} DrugCentral uuid:629483e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.56']} DrugCentral uuid:6294aea2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.071']} DrugCentral uuid:6294d7f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.538']} DrugCentral uuid:629500d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.135']} DrugCentral uuid:62952990-6b31-11ec-b3df-0242ac110002 UniProtKB:P10635 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Cytochrome P450 2D6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:6295524e-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.718']} DrugCentral uuid:62957c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22748 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.25']} DrugCentral uuid:6295a56e-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:6295ce54-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.14']} DrugCentral uuid:6295f730-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2D0 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 5B, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:6296207a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:62964a78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NR96 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Membrane receptor (Toll-like receptor 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:62967336-6b31-11ec-b3df-0242ac110002 UniProtKB:P07451 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.2']} DrugCentral uuid:62969c44-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.29']} DrugCentral uuid:6296c5b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.18']} DrugCentral uuid:6296ee88-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.111']} DrugCentral uuid:62971746-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N1Q1 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.16']} DrugCentral uuid:6297413a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q932Y6 biolink:molecularly_interacts_with DrugCentral:4733 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thiomersal targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.77']} DrugCentral uuid:62976a8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:6297adf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:6297adf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:6297adf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:6297adf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:6297adf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:6297adf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:6297adf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:6297adf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WPV7 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline is inhibitor of Enzyme (ATP synthase) DrugCentral uuid:62981b6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5TIX5 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline targets Enzyme (ATP synthase subunit c) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:6298444a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00845 biolink:molecularly_interacts_with DrugCentral:4741 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bedaquiline targets Enzyme (ATP synthase subunit c) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:62986d26-6b31-11ec-b3df-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:4744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crofelemer is inhibitor of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.155']} DrugCentral uuid:629896ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5XXA6 biolink:molecularly_interacts_with DrugCentral:4744 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crofelemer is inhibitor of Ion channel (Anoctamin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:6298bfa6-6b31-11ec-b3df-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:4746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pomalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:6298e882-6b31-11ec-b3df-0242ac110002 UniProtKB:A4TVL0 biolink:molecularly_interacts_with DrugCentral:4746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pomalidomide targets Unclassified (Cereblon isoform 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:62991244-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SW2 biolink:molecularly_interacts_with DrugCentral:4746 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pomalidomide is modulator of Cytosolic other (Protein cereblon) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.577']} DrugCentral uuid:62993b20-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4749 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ospemifene is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.082']} DrugCentral uuid:62996406-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobetaxolol is antagonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.1']} DrugCentral uuid:62998ce2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4752 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levobetaxolol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:6299b62c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDS4 biolink:molecularly_interacts_with DrugCentral:4757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyl fumarate targets GPCR (Hydroxycarboxylic acid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:6299e020-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14145 biolink:molecularly_interacts_with DrugCentral:4757 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dimethyl fumarate is inhibitor of Cytosolic other (Kelch-like ECH-associated protein 1) DrugCentral uuid:629a04d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.658']} DrugCentral uuid:629a2e36-6b31-11ec-b3df-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canagliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:629a57a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9YQ12 biolink:molecularly_interacts_with DrugCentral:4758 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canagliflozin targets Enzyme (Protease) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.2']} DrugCentral uuid:629a80b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.32']} DrugCentral uuid:629aa988-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.42']} DrugCentral uuid:629ad37c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:629afe56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.73']} DrugCentral uuid:629b2732-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16790 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.09']} DrugCentral uuid:629b500e-6b31-11ec-b3df-0242ac110002 UniProtKB:O43570 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.07']} DrugCentral uuid:629b78f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43166 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.06']} DrugCentral uuid:629ba248-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9ULX7 biolink:molecularly_interacts_with DrugCentral:4773 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ethyl hydroxybenzoate targets Enzyme (Carbonic anhydrase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.11']} DrugCentral uuid:629bcb56-6b31-11ec-b3df-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:4778 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ridaforolimus is inhibitor of Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.699']} DrugCentral uuid:629bf428-6b31-11ec-b3df-0242ac110002 UniProtKB:D2WKD8 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets Ion channel (Sodium/potassium-transporting ATPase subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.289']} DrugCentral uuid:629c1d86-6b31-11ec-b3df-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.736']} DrugCentral uuid:629c46e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.961']} DrugCentral uuid:629c6fac-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.477']} DrugCentral uuid:629c987e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.111']} DrugCentral uuid:629cc286-6b31-11ec-b3df-0242ac110002 UniProtKB:P21452 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets GPCR (Substance-K receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.818']} DrugCentral uuid:629cec66-6b31-11ec-b3df-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.497']} DrugCentral uuid:629d1542-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4794 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gramicidin targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.724']} DrugCentral uuid:629d3e1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5AJ71 biolink:molecularly_interacts_with DrugCentral:4796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium propionate targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.29']} DrugCentral uuid:629d677c-6b31-11ec-b3df-0242ac110002 UniProtKB:B2GV46 biolink:molecularly_interacts_with DrugCentral:4796 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium propionate targets GPCR (Free fatty acid receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:629d9058-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium nitrite targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['1.2']} DrugCentral uuid:629db952-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium nitrite targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['2.08']} DrugCentral uuid:629de350-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9D6N1 biolink:molecularly_interacts_with DrugCentral:4797 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sodium nitrite targets Enzyme (Carbonic anhydrase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['1.9']} DrugCentral uuid:629e0cc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilanterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:629e3594-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilanterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:629e5e52-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4799 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vilanterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:629e8724-6b31-11ec-b3df-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.82']} DrugCentral uuid:629eb1ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:629eda80-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:629f0366-6b31-11ec-b3df-0242ac110002 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:629f2c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:629f5596-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:629f7e72-6b31-11ec-b3df-0242ac110002 UniProtKB:P10398 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Serine/threonine-protein kinase A-Raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:629fa7ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.23']} DrugCentral uuid:629fd160-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:629ffa3c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:62a02318-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:62a04be0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:62a076ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y572 biolink:molecularly_interacts_with DrugCentral:4801 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dabrafenib targets Kinase (Receptor-interacting serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:62a0a0b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trametinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:62a0c99e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trametinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:62a0f2a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trametinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.036']} DrugCentral uuid:62a11be2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4802 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trametinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.61']} DrugCentral uuid:62a144c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4804 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palifermin is agonist of Kinase (Fibroblast growth factor receptor 2) DrugCentral uuid:62a16962-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:62a1939c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60492 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Membrane other (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.15']} DrugCentral uuid:62a1bdf4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62666 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Transporter (Vesicular acetylcholine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.34']} DrugCentral uuid:62a1e6e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.57']} DrugCentral uuid:62a20fc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5U3Y7 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir targets Unclassified (Sigma intracellular receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:62a239a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:4805 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dolutegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.131']} DrugCentral uuid:62a26290-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.34']} DrugCentral uuid:62a28b8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.25']} DrugCentral uuid:62a2b470-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:62a2ddec-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:62a306be-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.48']} DrugCentral uuid:62a32fc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:62a358b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.74']} DrugCentral uuid:62a38206-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.66']} DrugCentral uuid:62a3aae2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:62a3d3be-6b31-11ec-b3df-0242ac110002 UniProtKB:P23977 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:62a3fc86-6b31-11ec-b3df-0242ac110002 UniProtKB:P35563 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:62a426a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28565 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:62a44f88-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.699']} DrugCentral uuid:62a4788c-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.796']} DrugCentral uuid:62a4a190-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:62a4cb7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:62a4f474-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.481']} DrugCentral uuid:62a51ecc-6b31-11ec-b3df-0242ac110002 UniProtKB:P46098 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is antagonist of Ion channel (5-hydroxytryptamine receptor 3A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.432']} DrugCentral uuid:62a54848-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:4806 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vortioxetine is antagonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.268']} DrugCentral uuid:62a57142-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NP56 biolink:molecularly_interacts_with DrugCentral:4807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riociguat targets Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 7B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.538']} DrugCentral uuid:62a59a46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:4807 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 riociguat is positive allosteric modulator of Enzyme (Guanylate cyclase soluble subunit beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'MEC', 'has_quantitative_value': ['7.523']} DrugCentral uuid:62a5c444-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:62a5ef8c-6b31-11ec-b3df-0242ac110002 UniProtKB:O42275 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.77']} DrugCentral uuid:62a61ac0-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:62a64388-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JKC1 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Butyrylcholinesterase; Protein Bche) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.658']} DrugCentral uuid:62a66c64-6b31-11ec-b3df-0242ac110002 UniProtKB:P37136 biolink:molecularly_interacts_with DrugCentral:4808 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipidacrine targets Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.569']} DrugCentral uuid:62a695f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P25101 biolink:molecularly_interacts_with DrugCentral:4809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 macitentan is antagonist of GPCR (Endothelin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.301']} DrugCentral uuid:62a6beee-6b31-11ec-b3df-0242ac110002 UniProtKB:P24530 biolink:molecularly_interacts_with DrugCentral:4809 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 macitentan is antagonist of GPCR (Endothelin B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.408']} DrugCentral uuid:62a6e7c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.96']} DrugCentral uuid:62a71150-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:62a73ad6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:62a7643e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:62a78d74-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:62a7b72c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:62a7e0a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:62a80998-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.55']} DrugCentral uuid:62a832ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.48']} DrugCentral uuid:62a85c4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BRX8 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Unclassified (Redox-regulatory protein FAM213A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:62a8865c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.854']} DrugCentral uuid:62a8af60-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.495']} DrugCentral uuid:62a8d846-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.721']} DrugCentral uuid:62a901a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.201']} DrugCentral uuid:62a92a8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.387']} DrugCentral uuid:62a9537a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:62a97c60-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.194']} DrugCentral uuid:62a9a820-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:62a9d232-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.469']} DrugCentral uuid:62a9fb22-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:62aa23fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:62aa4d98-6b31-11ec-b3df-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.155']} DrugCentral uuid:62aa767e-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:62aa9f64-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:62aac8a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4810 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrutinib is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.143']} DrugCentral uuid:62aaf1a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:4811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sofosbuvir is inhibitor of Enzyme (NS5B protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.19']} DrugCentral uuid:62ab1a8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4811 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sofosbuvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC90', 'has_quantitative_value': ['6.959']} DrugCentral uuid:62ab434c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:62ab71b4-6b31-11ec-b3df-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:62ab71b4-6b31-11ec-b3df-0242ac110002 UniProtKB:D2K2A8 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir is inhibitor of Enzyme (Hepatitis C virus serine protease, NS3/NS4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:62aba71a-6b31-11ec-b3df-0242ac110002 UniProtKB:A0A0K1CY61 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir targets Unclassified (Nonstructural protein NS3-4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:62abd000-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6GYR8 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir is inhibitor of Polyprotein (Polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.44']} DrugCentral uuid:62abf8fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4812 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 simeprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.444']} DrugCentral uuid:62ac2262-6b31-11ec-b3df-0242ac110002 UniProtKB:P10613 biolink:molecularly_interacts_with DrugCentral:4813 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luliconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:62ac4706-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olodaterol targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:62ac6ff6-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olodaterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.26']} DrugCentral uuid:62ac99b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4814 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olodaterol is antagonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.14']} DrugCentral uuid:62acc2c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4815 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lixisenatide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.845']} DrugCentral uuid:62aceb98-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:62ad1492-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.9']} DrugCentral uuid:62ad3f08-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.796']} DrugCentral uuid:62ad683e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium targets GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.824']} DrugCentral uuid:62ad9156-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4816 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umeclidinium is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.222']} DrugCentral uuid:62adbb2c-6b31-11ec-b3df-0242ac110002 UniProtKB:O95342 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:62ade46c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6L6 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1B1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:62ae0d52-6b31-11ec-b3df-0242ac110002 UniProtKB:P46721 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin is inhibitor of Transporter (Solute carrier organic anion transporter family member 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:62ae36ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O70127 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin targets Transporter (Bile salt export pump) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:62ae5fa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0A8V2 biolink:molecularly_interacts_with DrugCentral:4817 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rifamycin is inhibitor of Enzyme (DNA-directed RNA polymerase subunit beta) DrugCentral uuid:62ae8494-6b31-11ec-b3df-0242ac110002 UniProtKB:P05067 biolink:molecularly_interacts_with DrugCentral:4818 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 florbetaben F18 targets Unclassified (Amyloid beta A4 protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.65']} DrugCentral uuid:62aead84-6b31-11ec-b3df-0242ac110002 UniProtKB:P48039 biolink:molecularly_interacts_with DrugCentral:4820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasimelteon is agonist of GPCR (Melatonin receptor type 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.45']} DrugCentral uuid:62aed674-6b31-11ec-b3df-0242ac110002 UniProtKB:P49286 biolink:molecularly_interacts_with DrugCentral:4820 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tasimelteon is agonist of GPCR (Melatonin receptor type 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:62aeff78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:4821 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 seractide is agonist of GPCR (Adrenocorticotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.009']} DrugCentral uuid:62af2b88-6b31-11ec-b3df-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:4822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laninamivir octanoate hydrate targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.89']} DrugCentral uuid:62af5464-6b31-11ec-b3df-0242ac110002 UniProtKB:Q194T1 biolink:molecularly_interacts_with DrugCentral:4822 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 laninamivir octanoate hydrate targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:62af7d40-6b31-11ec-b3df-0242ac110002 UniProtKB:B4URF0 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:62afa6d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10481 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Sialidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.4']} DrugCentral uuid:62afcfac-6b31-11ec-b3df-0242ac110002 UniProtKB:A5Z252 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:62aff874-6b31-11ec-b3df-0242ac110002 UniProtKB:P03470 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:62b02146-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y3R4 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Sialidase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.25']} DrugCentral uuid:62b04a9a-6b31-11ec-b3df-0242ac110002 UniProtKB:D5F1R0 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:62b0736c-6b31-11ec-b3df-0242ac110002 UniProtKB:P03471 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir targets Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:62b09c5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P03468 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.85']} DrugCentral uuid:62b0c538-6b31-11ec-b3df-0242ac110002 UniProtKB:P03474 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:62b0efa4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9IGQ6 biolink:molecularly_interacts_with DrugCentral:4823 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peramivir is inhibitor of Enzyme (Neuraminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.08']} DrugCentral uuid:62b118b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4824 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etilefrine pivalate is agonist of GPCR (Beta-1 adrenergic receptor) DrugCentral uuid:62b13d42-6b31-11ec-b3df-0242ac110002 UniProtKB:P48357 biolink:molecularly_interacts_with DrugCentral:4826 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 metreleptin is agonist of Membrane receptor (Leptin receptor) DrugCentral uuid:62b161e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07343 biolink:molecularly_interacts_with DrugCentral:4829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:62b18bbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P27815 biolink:molecularly_interacts_with DrugCentral:4829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:62b1b498-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08493 biolink:molecularly_interacts_with DrugCentral:4829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.93']} DrugCentral uuid:62b1de82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:4829 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apremilast is inhibitor of Enzyme (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.131']} DrugCentral uuid:62b20768-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M3M2 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin targets Transporter (Sodium/glucose cotransporter 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.959']} DrugCentral uuid:62b2309e-6b31-11ec-b3df-0242ac110002 UniProtKB:A0PJK1 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin targets Transporter (Sodium/glucose cotransporter 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.959']} DrugCentral uuid:62b25970-6b31-11ec-b3df-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.081']} DrugCentral uuid:62b28260-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WWX8 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin targets Transporter (Sodium/myo-inositol cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:62b2abd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4830 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 empagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.244']} DrugCentral uuid:62b2d79c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:4832 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naloxegol is antagonist of GPCR (Mu-type opioid receptor) DrugCentral uuid:62b2fc36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4833 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemigliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.328']} DrugCentral uuid:62b3251c-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4833 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemigliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:62b34e84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16739 biolink:molecularly_interacts_with DrugCentral:4834 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eliglustat is inhibitor of Enzyme (Ceramide glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.827']} DrugCentral uuid:62b37774-6b31-11ec-b3df-0242ac110002 UniProtKB:P00813 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets Enzyme (Adenosine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:62b3a05a-6b31-11ec-b3df-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:62b3c94a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:62b3f28a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.9']} DrugCentral uuid:62b41b84-6b31-11ec-b3df-0242ac110002 UniProtKB:P33033 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:62b4444c-6b31-11ec-b3df-0242ac110002 UniProtKB:P41149 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:62b46d28-6b31-11ec-b3df-0242ac110002 UniProtKB:P56450 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:62b497d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01727 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide targets GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:62b4c1ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:4836 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 afamelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:62b4eaa0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:4839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprotinin is inhibitor of Enzyme (Plasminogen) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.8']} DrugCentral uuid:62b51386-6b31-11ec-b3df-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:4839 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aprotinin is inhibitor of Enzyme (Plasma kallikrein) DrugCentral uuid:62b538ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:4846 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ecallantide is inhibitor of Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.602']} DrugCentral uuid:62b561ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:4848 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatropin is agonist of GPCR (Growth hormone receptor) DrugCentral uuid:62b58640-6b31-11ec-b3df-0242ac110002 UniProtKB:P00761 biolink:molecularly_interacts_with DrugCentral:4853 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cridanimod targets Enzyme (Trypsin) {'has_attribute_type': 'IAO:0000004', 'name': 'AC50', 'has_quantitative_value': ['5.15']} DrugCentral uuid:62b5af12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3TBT3 biolink:molecularly_interacts_with DrugCentral:4853 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cridanimod targets Unclassified (Stimulator of interferon genes protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:62b5d9c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conjugated estrogens is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:62b5ff76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4855 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 conjugated estrogens is agonist of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:62b623fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08842 biolink:molecularly_interacts_with DrugCentral:4857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone sulphate targets Enzyme (Steryl-sulfatase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.22']} DrugCentral uuid:62b64cec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q80UJ1 biolink:molecularly_interacts_with DrugCentral:4857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone sulphate targets Transporter (Solute carrier family 22 member 20) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.24']} DrugCentral uuid:62b677e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:4857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone sulphate is agonist of Nuclear hormone receptor (Estrogen receptor) DrugCentral uuid:62b69c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:4857 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estrone sulphate is agonist of Nuclear hormone receptor (Estrogen receptor beta) DrugCentral uuid:62b6c122-6b31-11ec-b3df-0242ac110002 UniProtKB:Q60748 biolink:molecularly_interacts_with DrugCentral:4858 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:62b6e9fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P47866 biolink:molecularly_interacts_with DrugCentral:4858 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.9']} DrugCentral uuid:62b7137a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13324 biolink:molecularly_interacts_with DrugCentral:4858 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:62b73c74-6b31-11ec-b3df-0242ac110002 UniProtKB:P34998 biolink:molecularly_interacts_with DrugCentral:4858 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticorelin is agonist of GPCR (Corticotropin-releasing factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.481']} DrugCentral uuid:62b76942-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenibut is agonist of GPCR (GABA-B receptor) DrugCentral uuid:62b76942-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBS5 biolink:molecularly_interacts_with DrugCentral:4863 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 phenibut is agonist of GPCR (GABA-B receptor) DrugCentral uuid:62b79886-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:62b7c14e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31652 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.07']} DrugCentral uuid:62b8017c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:62b8017c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:62b8017c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:62b8017c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:62b8017c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:62b8017c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:62b8017c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R1M7 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran targets Ion channel (Glutamate NMDA receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.2']} DrugCentral uuid:62b8781e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.951']} DrugCentral uuid:62b8a122-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:4864 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 levomilnacipran is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.035']} DrugCentral uuid:62b8ca30-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebanazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) DrugCentral uuid:62b8ef74-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:4865 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mebanazine is inhibitor of Enzyme (Amine oxidase [flavin-containing] A) DrugCentral uuid:62b913fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:62b93cc2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:62b966a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:62b98fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:62b9b8aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:62b9e168-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:62ba0b52-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:62ba3640-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:62ba5f12-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:62ba87da-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:62bab138-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:62bada64-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.94']} DrugCentral uuid:62bb0318-6b31-11ec-b3df-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.4']} DrugCentral uuid:62bb2bfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.37']} DrugCentral uuid:62bb5520-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:62bb7dfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.56']} DrugCentral uuid:62bba6ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:62bbcfa0-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:62bbfc96-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:62bc2568-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.87']} DrugCentral uuid:62bc4e30-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:62bc77a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:62bca088-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.71']} DrugCentral uuid:62bcc950-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.65']} DrugCentral uuid:62bcf218-6b31-11ec-b3df-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:62bd1b58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:62bd4420-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:62bd6df6-6b31-11ec-b3df-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.02']} DrugCentral uuid:62bd96d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:62bdc0b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:62bde970-6b31-11ec-b3df-0242ac110002 UniProtKB:P41212 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Transcription factor (Transcription factor ETV6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:62be1238-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.05']} DrugCentral uuid:62be3b8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.097']} DrugCentral uuid:62be64d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.155']} DrugCentral uuid:62be8db2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.638']} DrugCentral uuid:62beb68e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4866 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ceritinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.699']} DrugCentral uuid:62bedf6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:62bf090e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:62bf31ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.74']} DrugCentral uuid:62bf5ada-6b31-11ec-b3df-0242ac110002 UniProtKB:P49327 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (Fatty acid synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.23']} DrugCentral uuid:62bf847e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:62bfaf94-6b31-11ec-b3df-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:62bfd866-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFI3 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (Cytosolic endo-beta-N-acetylglucosaminidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.35']} DrugCentral uuid:62c00124-6b31-11ec-b3df-0242ac110002 UniProtKB:O94760 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.28']} DrugCentral uuid:62c02a64-6b31-11ec-b3df-0242ac110002 UniProtKB:P14735 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Enzyme (Insulin-degrading enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:62c05340-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6SZW1 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole targets Unclassified (Sterile alpha and TIR motif-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:62c0800e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:62c0800e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4867 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dexrabeprazole is inhibitor of Transporter (Potassium-transporting ATPase) DrugCentral uuid:62c0af0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P25116 biolink:molecularly_interacts_with DrugCentral:4870 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vorapaxar is antagonist of GPCR (Proteinase-activated receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.092']} DrugCentral uuid:62c0d892-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tedizolid phosphate targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:62c1016e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:4873 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tedizolid phosphate targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.06']} DrugCentral uuid:62c12a4a-6b31-11ec-b3df-0242ac110002 UniProtKB:F2SHH3 biolink:molecularly_interacts_with DrugCentral:4874 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efinaconazole is inhibitor of Enzyme (Lanosterol 14-alpha demethylase) DrugCentral uuid:62c14fb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.53']} DrugCentral uuid:62c17b9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.64']} DrugCentral uuid:62c1a47a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.64']} DrugCentral uuid:62c1cd4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.046']} DrugCentral uuid:62c1f66e-6b31-11ec-b3df-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4875 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.301']} DrugCentral uuid:62c21f54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQL6 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.6']} DrugCentral uuid:62c24830-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:62c2712a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:62c29bc8-6b31-11ec-b3df-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:62c2c4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBN7 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:62c2ee34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WUI4 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.29']} DrugCentral uuid:62c31738-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:62c3421c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKV0 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.62']} DrugCentral uuid:62c36b2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.23']} DrugCentral uuid:62c3941a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9XYC7 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat targets Enzyme (Histone deacetylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.67']} DrugCentral uuid:62c3bd00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:62c3e62c-6b31-11ec-b3df-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.57']} DrugCentral uuid:62c40f1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P56524 biolink:molecularly_interacts_with DrugCentral:4876 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belinostat is inhibitor of Enzyme (Histone deacetylase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.569']} DrugCentral uuid:62c437ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.33']} DrugCentral uuid:62c46124-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:62c48db6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTL6 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:62c4b69c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3I4V7 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.05']} DrugCentral uuid:62c4df6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P26637 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole targets Enzyme (Leucine--tRNA ligase, cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.73']} DrugCentral uuid:62c5093a-6b31-11ec-b3df-0242ac110002 UniProtKB:F2SF18 biolink:molecularly_interacts_with DrugCentral:4877 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tavaborole is inhibitor of Enzyme (Leucine-tRNA ligase) DrugCentral uuid:62c52db6-6b31-11ec-b3df-0242ac110002 UniProtKB:P78527 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (DNA-dependent protein kinase catalytic subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:62c55796-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NEB9 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 3-kinase catalytic subunit type 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.36']} DrugCentral uuid:62c58072-6b31-11ec-b3df-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.086']} DrugCentral uuid:62c5a9a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.248']} DrugCentral uuid:62c5d270-6b31-11ec-b3df-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.051']} DrugCentral uuid:62c5fb56-6b31-11ec-b3df-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:4878 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 idelalisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.602']} DrugCentral uuid:62c62432-6b31-11ec-b3df-0242ac110002 UniProtKB:P01008 biolink:molecularly_interacts_with DrugCentral:4879 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enoxaparin sodium is activator of Secreted (Antithrombin-III) DrugCentral uuid:62c6496c-6b31-11ec-b3df-0242ac110002 UniProtKB:P58308 biolink:molecularly_interacts_with DrugCentral:4881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suvorexant targets GPCR (Orexin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.06']} DrugCentral uuid:62c67234-6b31-11ec-b3df-0242ac110002 UniProtKB:P58307 biolink:molecularly_interacts_with DrugCentral:4881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suvorexant targets GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:62c69b24-6b31-11ec-b3df-0242ac110002 UniProtKB:O43613 biolink:molecularly_interacts_with DrugCentral:4881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suvorexant is antagonist of GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:62c6c414-6b31-11ec-b3df-0242ac110002 UniProtKB:O43614 biolink:molecularly_interacts_with DrugCentral:4881 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 suvorexant is antagonist of GPCR (Orexin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.456']} DrugCentral uuid:62c6edea-6b31-11ec-b3df-0242ac110002 UniProtKB:P30542 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.08']} DrugCentral uuid:62c716c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P29275 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A2b) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.75']} DrugCentral uuid:62c73f98-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.35']} DrugCentral uuid:62c768b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:62c79286-6b31-11ec-b3df-0242ac110002 UniProtKB:P25099 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.82']} DrugCentral uuid:62c7bb6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30543 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.7']} DrugCentral uuid:62c7e448-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.57']} DrugCentral uuid:62c80d4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P29274 biolink:molecularly_interacts_with DrugCentral:4882 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 istradefylline is antagonist of GPCR (Adenosine receptor A2a) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.66']} DrugCentral uuid:62c836e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4885 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dulaglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) DrugCentral uuid:62c85b80-6b31-11ec-b3df-0242ac110002 UniProtKB:P16233 biolink:molecularly_interacts_with DrugCentral:4886 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetilistat is inhibitor of Enzyme (Pancreatic triacylglycerol lipase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.225']} DrugCentral uuid:62c884fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P80457 biolink:molecularly_interacts_with DrugCentral:4888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiroxostat targets Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.32']} DrugCentral uuid:62c8af68-6b31-11ec-b3df-0242ac110002 UniProtKB:P47989 biolink:molecularly_interacts_with DrugCentral:4888 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 topiroxostat is inhibitor of Enzyme (Xanthine dehydrogenase/oxidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.276']} DrugCentral uuid:62c8d89e-6b31-11ec-b3df-0242ac110002 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:4889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asunaprevir targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:62c9017a-6b31-11ec-b3df-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4889 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 asunaprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.398']} DrugCentral uuid:62c92a74-6b31-11ec-b3df-0242ac110002 UniProtKB:P53792 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:62c95602-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8C3K6 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:62c98046-6b31-11ec-b3df-0242ac110002 UniProtKB:P53790 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.93']} DrugCentral uuid:62c9a936-6b31-11ec-b3df-0242ac110002 UniProtKB:Q923I7 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.25']} DrugCentral uuid:62c9d208-6b31-11ec-b3df-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.727']} DrugCentral uuid:62c9fb8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4890 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipragliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.132']} DrugCentral uuid:62ca256e-6b31-11ec-b3df-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luseogliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.399']} DrugCentral uuid:62ca4e40-6b31-11ec-b3df-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4891 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luseogliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.646']} DrugCentral uuid:62ca771c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:4892 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofogliflozin targets Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.073']} DrugCentral uuid:62caa246-6b31-11ec-b3df-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:4892 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tofogliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.538']} DrugCentral uuid:62cacb36-6b31-11ec-b3df-0242ac110002 UniProtKB:P07650 biolink:molecularly_interacts_with DrugCentral:4893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipiracil targets Enzyme (Thymidine phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:62caf426-6b31-11ec-b3df-0242ac110002 UniProtKB:P19971 biolink:molecularly_interacts_with DrugCentral:4893 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tipiracil is inhibitor of Enzyme (Thymidine phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:62cb1d66-6b31-11ec-b3df-0242ac110002 UniProtKB:P14174 biolink:molecularly_interacts_with DrugCentral:4894 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 iguratimod targets Unclassified (Macrophage migration inhibitory factor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.17']} DrugCentral uuid:62cb462e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14740 biolink:molecularly_interacts_with DrugCentral:4895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teneligliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.54']} DrugCentral uuid:62cb6ef6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:4895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teneligliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.585']} DrugCentral uuid:62cb97c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teneligliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.268']} DrugCentral uuid:62cbc14e-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4895 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teneligliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.432']} DrugCentral uuid:62cbea16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12884 biolink:molecularly_interacts_with DrugCentral:4896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagliptin targets Enzyme (Prolyl endopeptidase FAP) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:62cc12de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6V1X1 biolink:molecularly_interacts_with DrugCentral:4896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagliptin targets Enzyme (Dipeptidyl peptidase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.167']} DrugCentral uuid:62cc3bc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86TI2 biolink:molecularly_interacts_with DrugCentral:4896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagliptin targets Enzyme (Dipeptidyl peptidase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:62cc66b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:4896 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:62cc936c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:4897 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 edoxaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.252']} DrugCentral uuid:62ccbd7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:4898 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 netupitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.022']} DrugCentral uuid:62cce678-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ledipasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.51']} DrugCentral uuid:62cd0fa4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ledipasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.51']} DrugCentral uuid:62cd3858-6b31-11ec-b3df-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ledipasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:62cd6206-6b31-11ec-b3df-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4899 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ledipasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.509']} DrugCentral uuid:62cd8ae2-6b31-11ec-b3df-0242ac110002 UniProtKB:P51582 biolink:molecularly_interacts_with DrugCentral:4900 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diquafosol is agonist of GPCR (P2Y purinoceptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:62cdb45e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41231 biolink:molecularly_interacts_with DrugCentral:4900 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 diquafosol is agonist of GPCR (P2Y purinoceptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.469']} DrugCentral uuid:62cddd1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4901 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin glargine is agonist of Kinase (Insulin receptor) DrugCentral uuid:62ce0198-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:4902 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imidafenacin targets GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kb', 'has_quantitative_value': ['8.384']} DrugCentral uuid:62ce2b8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:4902 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imidafenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kb', 'has_quantitative_value': ['9.499']} DrugCentral uuid:62ce559e-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.09']} DrugCentral uuid:62ce7e84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.59']} DrugCentral uuid:62cea738-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:62ced064-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:62cef940-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:62cf2212-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.57']} DrugCentral uuid:62cf4ada-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:62cf7460-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.21']} DrugCentral uuid:62cf9d3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:62cfc618-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:62cfeee0-6b31-11ec-b3df-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:62d01a64-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.38']} DrugCentral uuid:62d04598-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.02']} DrugCentral uuid:62d06e60-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:62d09750-6b31-11ec-b3df-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:62d0c0a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:62d0e976-6b31-11ec-b3df-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:62d11248-6b31-11ec-b3df-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:62d13bc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:62d165cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is agonist of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.62']} DrugCentral uuid:62d18ebc-6b31-11ec-b3df-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:62d1b7b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:62d1e182-6b31-11ec-b3df-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:62d20a7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:62d2334e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:62d25ca2-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:62d28600-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.32']} DrugCentral uuid:62d2aed2-6b31-11ec-b3df-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:62d2d7a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.49']} DrugCentral uuid:62d3008a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.35']} DrugCentral uuid:62d32a06-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:62d352ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:62d37bbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:62d3a486-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:62d3ce70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:62d3f756-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:62d42028-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:62d44968-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:62d47244-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:62d49b2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:62d4c406-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:62d4ed6e-6b31-11ec-b3df-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:62d5165e-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:62d53f26-6b31-11ec-b3df-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:62d568f2-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:62d59304-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:62d5bbe0-6b31-11ec-b3df-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:62d5e4b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.66']} DrugCentral uuid:62d60d84-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:62d636ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:62d65fb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:62d68890-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:62d6b176-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:62d6dafc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:62d703d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:62d72dea-6b31-11ec-b3df-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:62d757fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:62d78204-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.51']} DrugCentral uuid:62d7aad6-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:62d7d3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.66']} DrugCentral uuid:62d7fcde-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:62d825b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.06']} DrugCentral uuid:62d84e82-6b31-11ec-b3df-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:62d8775e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:62d8a116-6b31-11ec-b3df-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:62d8c9e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:62d8f2ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:62d91baa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:62d94670-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:62d970b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:62d999a4-6b31-11ec-b3df-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:62d9c2da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.29']} DrugCentral uuid:62d9ebb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:62da1492-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:62da3d64-6b31-11ec-b3df-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:62da66f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.2']} DrugCentral uuid:62da8fda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:62dab8b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:62dae192-6b31-11ec-b3df-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:62db0c12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:62db34ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:62db5dc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:62db8692-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:62dbafd2-6b31-11ec-b3df-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:62dbd8a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:62dc01a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:62dc2a7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:62dc53ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:62dc7cd2-6b31-11ec-b3df-0242ac110002 UniProtKB:P49840 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Glycogen synthase kinase-3 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:62dca59a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:62dcce76-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:62dcfb30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:62dd2556-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.31']} DrugCentral uuid:62dd4e32-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:62dd7844-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:62dda134-6b31-11ec-b3df-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:62ddca1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:62ddf440-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:62de1dc6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:62de46ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:62de6f88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:62de986e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:62dec38e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:62deec6a-6b31-11ec-b3df-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:62df1546-6b31-11ec-b3df-0242ac110002 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:62df3e18-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:62df6776-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07002 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 18) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:62df9052-6b31-11ec-b3df-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:62dfb924-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:62dfe296-6b31-11ec-b3df-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:62e00bf4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:62e034c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:62e05d8e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:62e087f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.64']} DrugCentral uuid:62e0b216-6b31-11ec-b3df-0242ac110002 UniProtKB:P48730 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Casein kinase I isoform delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:62e0dae8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:62e103ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.49']} DrugCentral uuid:62e12d04-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:62e155d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:62e17f98-6b31-11ec-b3df-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:62e1a874-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:62e1d1e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:62e1fac2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.74']} DrugCentral uuid:62e2239e-6b31-11ec-b3df-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:62e24c66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.31']} DrugCentral uuid:62e2770e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:62e29fe0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:62e2c8c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:62e2f21a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:62e31aec-6b31-11ec-b3df-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:62e343c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:62e36cae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:62e39634-6b31-11ec-b3df-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:62e3befc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:62e3e7ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:62e410be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:62e43b34-6b31-11ec-b3df-0242ac110002 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:62e463e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:62e48cc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:62e4b5b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:62e4e016-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:62e508d4-6b31-11ec-b3df-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:62e531a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:62e55bfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:62e584da-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:62e5ada2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.25']} DrugCentral uuid:62e5d66a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:62e60054-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:62e62926-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:62e6522a-6b31-11ec-b3df-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:62e67afc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.07']} DrugCentral uuid:62e6a446-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16566 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium/calmodulin-dependent protein kinase type IV) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:62e6cda4-6b31-11ec-b3df-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:62e6f68a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:62e71f5c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.15']} DrugCentral uuid:62e748ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:62e771c8-6b31-11ec-b3df-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:62e79a9a-6b31-11ec-b3df-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:62e7c376-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WXR4 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin-IIIb) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:62e7ed06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:62e815ce-6b31-11ec-b3df-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:62e83e78-6b31-11ec-b3df-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:62e8674a-6b31-11ec-b3df-0242ac110002 UniProtKB:P36897 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (TGF-beta receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:62e89062-6b31-11ec-b3df-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:62e8b9a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:62e8e274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:62e90c04-6b31-11ec-b3df-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:62e934f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:62e95eb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:62e98788-6b31-11ec-b3df-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.74']} DrugCentral uuid:62e9b1ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:62e9da8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:62ea0370-6b31-11ec-b3df-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:62ea2c4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:62ea5578-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:62ea7e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:62eaa712-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:62eacfda-6b31-11ec-b3df-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:62eaf960-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:62eb2232-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:62eb4b18-6b31-11ec-b3df-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:62eb73d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:62eb9e88-6b31-11ec-b3df-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:62ebc75a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:62ebf022-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:62ec194e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:62ec4216-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:62ec6afc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:62ec93e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:62ecbd5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:62ece63a-6b31-11ec-b3df-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:62ed0f20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.03']} DrugCentral uuid:62ed3810-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.47']} DrugCentral uuid:62ed62cc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:62ed8c34-6b31-11ec-b3df-0242ac110002 UniProtKB:O95747 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase OSR1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:62edb510-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:62edddec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:62ee0722-6b31-11ec-b3df-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.39']} DrugCentral uuid:62ee2ffe-6b31-11ec-b3df-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:62ee58da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:62ee81b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.22']} DrugCentral uuid:62eeab28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.28']} DrugCentral uuid:62eed3f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:62eefccc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6ZN16 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:62ef2698-6b31-11ec-b3df-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:62ef4f6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:62ef7846-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:62efa122-6b31-11ec-b3df-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:62efca58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.08']} DrugCentral uuid:62eff334-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:62f01c10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:62f044ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.74']} DrugCentral uuid:62f06e68-6b31-11ec-b3df-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:62f09762-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.43']} DrugCentral uuid:62f0c048-6b31-11ec-b3df-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:62f0e942-6b31-11ec-b3df-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:62f11552-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.44']} DrugCentral uuid:62f14248-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13976 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Kinase (cGMP-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:62f16b42-6b31-11ec-b3df-0242ac110002 UniProtKB:P08183 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib targets Transporter (Multidrug resistance protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:62f19482-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.983']} DrugCentral uuid:62f1bd68-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:62f1e658-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:62f20f2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:62f2389c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4903 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nintedanib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.42']} DrugCentral uuid:62f26182-6b31-11ec-b3df-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4904 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 adalimumab is antibody binding of Cytokine (Tumor necrosis factor) DrugCentral uuid:62f28752-6b31-11ec-b3df-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4905 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pegaptanib is antagonist of Secreted (Vascular endothelial growth factor A) DrugCentral uuid:62f2abec-6b31-11ec-b3df-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:4906 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fimasartan is antagonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.377']} DrugCentral uuid:62f2d64e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:62f30024-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKK3 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:62f3296e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q53GL7 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.9']} DrugCentral uuid:62f35254-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0J9 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:62f37b94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q460N3 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Poly [ADP-ribose] polymerase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:62f3a47a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2NL67 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Unclassified (Poly [ADP-ribose] polymerase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.75']} DrugCentral uuid:62f3cd42-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N5Y8 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Unclassified (Mono [ADP-ribose] polymerase PARP16) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:62f3f632-6b31-11ec-b3df-0242ac110002 UniProtKB:O95271 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib targets Enzyme (Tankyrase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.824']} DrugCentral uuid:62f41fae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:62f44894-6b31-11ec-b3df-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:62f47166-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6F1 biolink:molecularly_interacts_with DrugCentral:4907 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:62f49a4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P22303 biolink:molecularly_interacts_with DrugCentral:4908 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acotiamide is inhibitor of Enzyme (Acetylcholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.523']} DrugCentral uuid:62f4c526-6b31-11ec-b3df-0242ac110002 UniProtKB:P31358 biolink:molecularly_interacts_with DrugCentral:4909 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alemtuzumab is antibody binding of Surface antigen (CAMPATH-1 antigen) DrugCentral uuid:62f4e9c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P37288 biolink:molecularly_interacts_with DrugCentral:4910 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 felypressin is agonist of GPCR (Vasopressin V1a receptor) DrugCentral uuid:62f50e3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:4912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ombitasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.85']} DrugCentral uuid:62f53718-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WMX2 biolink:molecularly_interacts_with DrugCentral:4912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ombitasvir targets Unclassified (Genome polyprotein [Cleaved into: Core protein p21) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.92']} DrugCentral uuid:62f5613e-6b31-11ec-b3df-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ombitasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.301']} DrugCentral uuid:62f58a10-6b31-11ec-b3df-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:4912 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ombitasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.854']} DrugCentral uuid:62f5b2e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:4914 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasabuvir targets Enzyme (NS5B protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:62f5dc5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8JXU8 biolink:molecularly_interacts_with DrugCentral:4914 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasabuvir targets Unclassified (NS5B protein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:62f6051c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:4915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blinatumomab is antibody binding of Surface antigen (B-lymphocyte antigen CD19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:62f635b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:4915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blinatumomab is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:62f635b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:4915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blinatumomab is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:62f635b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:4915 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 blinatumomab is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:62f677cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aflibercept is inhibitor of Secreted (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['12.301']} DrugCentral uuid:62f6a2e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P49763 biolink:molecularly_interacts_with DrugCentral:4916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aflibercept is inhibitor of Secreted (Placenta growth factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.409']} DrugCentral uuid:62f6cbf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P49765 biolink:molecularly_interacts_with DrugCentral:4916 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aflibercept is inhibitor of Secreted (Vascular endothelial growth factor B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.717']} DrugCentral uuid:62f6f4cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4917 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ramucirumab is antibody binding of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.3']} DrugCentral uuid:62f71e20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15858 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Ion channel (Sodium channel protein type 9 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:62f746e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P21397 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Enzyme (Amine oxidase [flavin-containing] A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:62f76fc4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9R0C9 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Membrane receptor (Sigma non-opioid intracellular receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.71']} DrugCentral uuid:62f799a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P19643 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.59']} DrugCentral uuid:62f7cab4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:62f7cab4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:62f7cab4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08104 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide targets Ion channel (Sodium channel alpha subunits; brain (Types I, II, III)) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:62f80c22-6b31-11ec-b3df-0242ac110002 UniProtKB:P27338 biolink:molecularly_interacts_with DrugCentral:4921 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 safinamide is inhibitor of Enzyme (Amine oxidase [flavin-containing] B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.347']} DrugCentral uuid:62f83530-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:4923 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 nivolumab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.14']} DrugCentral uuid:62f85ee8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:4924 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pembrolizumab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:62f88bac-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 becaplermin is agonist of Kinase (Platelet-derived growth factor receptor) DrugCentral uuid:62f88bac-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4925 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 becaplermin is agonist of Kinase (Platelet-derived growth factor receptor) DrugCentral uuid:62f8bbfe-6b31-11ec-b3df-0242ac110002 UniProtKB:P32301 biolink:molecularly_interacts_with DrugCentral:4927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albiglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:62f8e674-6b31-11ec-b3df-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:4927 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 albiglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.699']} DrugCentral uuid:62f90f5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23945 biolink:molecularly_interacts_with DrugCentral:4928 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 follitropin is agonist of GPCR (Follicle-stimulating hormone receptor) DrugCentral uuid:62f933ea-6b31-11ec-b3df-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:4929 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lutropin alfa is agonist of GPCR (Lutropin-choriogonadotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.9']} DrugCentral uuid:62f95cda-6b31-11ec-b3df-0242ac110002 UniProtKB:P16473 biolink:molecularly_interacts_with DrugCentral:4930 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 thyrotropin alfa is agonist of GPCR (Thyrotropin receptor) DrugCentral uuid:62f98246-6b31-11ec-b3df-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.16']} DrugCentral uuid:62f9ab22-6b31-11ec-b3df-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.06']} DrugCentral uuid:62f9d426-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:62f9fd16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Adrenocorticotropic hormone receptor) DrugCentral uuid:62fa22e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q64326 biolink:molecularly_interacts_with DrugCentral:4931 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corticotropin is agonist of GPCR (Adrenocorticotropic hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.8']} DrugCentral uuid:62fa5036-6b31-11ec-b3df-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:4933 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocilizumab is antibody binding of Membrane receptor (Interleukin-6 receptor) DrugCentral uuid:62fa5036-6b31-11ec-b3df-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:4933 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tocilizumab is antibody binding of Membrane receptor (Interleukin-6 receptor) DrugCentral uuid:62fa7f52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16552 biolink:molecularly_interacts_with DrugCentral:4934 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 secukinumab is antibody binding of Cytokine (Interleukin-17A) DrugCentral uuid:62faa40a-6b31-11ec-b3df-0242ac110002 UniProtKB:P03420 biolink:molecularly_interacts_with DrugCentral:4935 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palivizumab is antibody binding of Surface antigen (Fusion glycoprotein F0) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.357']} DrugCentral uuid:62facd4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03431 biolink:molecularly_interacts_with DrugCentral:4936 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 parathyroid hormone is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) DrugCentral uuid:62faf1da-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:62fb1ad4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:62fb439c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.7']} DrugCentral uuid:62fb6d18-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:62fb9612-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.721']} DrugCentral uuid:62fbbf2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4937 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alectinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.319']} DrugCentral uuid:62fbe7f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:4938 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripasudil is inhibitor of Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:62fc1470-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:4938 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripasudil is inhibitor of Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.292']} DrugCentral uuid:62fc3e32-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:4938 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripasudil is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.721']} DrugCentral uuid:62fc6704-6b31-11ec-b3df-0242ac110002 UniProtKB:P25774 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir targets Enzyme (Cathepsin S) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.11']} DrugCentral uuid:62fc90c6-6b31-11ec-b3df-0242ac110002 UniProtKB:A0A0K1CY61 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir targets Unclassified (Nonstructural protein NS3-4A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.3']} DrugCentral uuid:62fcb9a2-6b31-11ec-b3df-0242ac110002 UniProtKB:K7XJL6 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir targets Unclassified (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.66']} DrugCentral uuid:62fce3aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.301']} DrugCentral uuid:62fd0cb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99IB8 biolink:molecularly_interacts_with DrugCentral:4939 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vaniprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.046']} DrugCentral uuid:62fd3648-6b31-11ec-b3df-0242ac110002 UniProtKB:P01589 biolink:molecularly_interacts_with DrugCentral:4940 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 basiliximab is antibody binding of Membrane receptor (Interleukin-2 receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:62fd5f10-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:62fd8800-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:62fdb0d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:62fddfee-6b31-11ec-b3df-0242ac110002 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:62fddfee-6b31-11ec-b3df-0242ac110002 UniProtKB:P24385 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (Cyclin-dependent kinase 4/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:62fe18c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (CDK2/Cyclin A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:62fe18c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (CDK2/Cyclin A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:62fe514a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (CDK6/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:62fe514a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib targets Kinase (CDK6/cyclin D1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:62fe8674-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib is inhibitor of Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.097']} DrugCentral uuid:62feaf82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib is inhibitor of Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.699']} DrugCentral uuid:62fed85e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:62ff031a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:4941 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 palbociclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.959']} DrugCentral uuid:62ff2bec-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:62ff54dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35218 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib targets Enzyme (Carbonic anhydrase 5A, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.88']} DrugCentral uuid:62ff7dcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.409']} DrugCentral uuid:62ffa84c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.187']} DrugCentral uuid:62ffd178-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:62fffa7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:63002362-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.658']} DrugCentral uuid:63004cac-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.398']} DrugCentral uuid:63007588-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.284']} DrugCentral uuid:63009f7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.292']} DrugCentral uuid:6300c862-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:4942 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenvatinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.337']} DrugCentral uuid:6300f1de-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:4943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arformoterol targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.6']} DrugCentral uuid:63011a9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8K4Z4 biolink:molecularly_interacts_with DrugCentral:4943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arformoterol targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.9']} DrugCentral uuid:630143f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:4943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arformoterol is agonist of GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.947']} DrugCentral uuid:63016cd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:4943 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 arformoterol is agonist of GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.538']} DrugCentral uuid:630196a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P32238 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10']} DrugCentral uuid:6301bf74-6b31-11ec-b3df-0242ac110002 UniProtKB:P32239 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin is agonist of GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:6301e846-6b31-11ec-b3df-0242ac110002 UniProtKB:P30551 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin is agonist of GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.3']} DrugCentral uuid:63021186-6b31-11ec-b3df-0242ac110002 UniProtKB:P30553 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.39']} DrugCentral uuid:63023a8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P56481 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin targets GPCR (Gastrin/cholecystokinin type B receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:63026352-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63931 biolink:molecularly_interacts_with DrugCentral:4945 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pancreozymin targets GPCR (Cholecystokinin receptor type A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.55']} DrugCentral uuid:63028c4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam targets Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:6302b5b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD65 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam targets Enzyme (Penicillin-binding protein 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.23']} DrugCentral uuid:6302de86-6b31-11ec-b3df-0242ac110002 UniProtKB:P05364 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.155']} DrugCentral uuid:6303076c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24735 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:6303305c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9EXV5 biolink:molecularly_interacts_with DrugCentral:4946 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avibactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.699']} DrugCentral uuid:63035bc2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y275 biolink:molecularly_interacts_with DrugCentral:4949 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belimumab is antibody binding of Cytokine (Tumor necrosis factor ligand superfamily member 13B) DrugCentral uuid:630384c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:4950 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abciximab is antibody binding of Adhesion (Integrin alpha-IIb/beta-3) DrugCentral uuid:630384c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P08514 biolink:molecularly_interacts_with DrugCentral:4950 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abciximab is antibody binding of Adhesion (Integrin alpha-IIb/beta-3) DrugCentral uuid:6303b3ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4951 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ofatumumab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.92']} DrugCentral uuid:6303dcaa-6b31-11ec-b3df-0242ac110002 UniProtKB:P01584 biolink:molecularly_interacts_with DrugCentral:4952 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 canakinumab is antibody binding of Cytokine (Interleukin-1 beta) DrugCentral uuid:6304096e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:4953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclizumab is antibody binding of Membrane receptor (Interleukin-2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:6304096e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:4953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclizumab is antibody binding of Membrane receptor (Interleukin-2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:6304096e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:4953 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daclizumab is antibody binding of Membrane receptor (Interleukin-2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:63044a64-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4954 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cetuximab is antibody binding of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.41']} DrugCentral uuid:6304746c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:4955 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 panitumumab is agonist of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.3']} DrugCentral uuid:63049e2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4956 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bevacizumab is antibody binding of Secreted (Vascular endothelial growth factor A) DrugCentral uuid:6304c2be-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4957 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pertuzumab is antibody binding of Kinase (Receptor tyrosine-protein kinase erbB-2) DrugCentral uuid:6304e74e-6b31-11ec-b3df-0242ac110002 UniProtKB:P16410 biolink:molecularly_interacts_with DrugCentral:4958 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ipilimumab is antibody binding of Surface antigen (Cytotoxic T-lymphocyte protein 4) DrugCentral uuid:63050be8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20701 biolink:molecularly_interacts_with DrugCentral:4959 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 efalizumab is antibody binding of Adhesion (Leukocyte adhesion glycoprotein LFA-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.4']} DrugCentral uuid:630537d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4960 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin degludec is agonist of Kinase (Insulin receptor) DrugCentral uuid:63055cec-6b31-11ec-b3df-0242ac110002 UniProtKB:P13423 biolink:molecularly_interacts_with DrugCentral:4961 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 raxibacumab is antibody binding of Secreted (Protective antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.556']} DrugCentral uuid:630587a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P28908 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is binding agent of Membrane receptor (Tumor necrosis factor receptor superfamily member 8) DrugCentral uuid:6305cb96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6305cb96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6305cb96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6305cb96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6305cb96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6305cb96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6305cb96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6305cb96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6305cb96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4964 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brentuximab vedotin is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:63064346-6b31-11ec-b3df-0242ac110002 UniProtKB:O14788 biolink:molecularly_interacts_with DrugCentral:4965 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denosumab is antibody binding of Cytokine (Tumor necrosis factor ligand superfamily member 11) DrugCentral uuid:63066c68-6b31-11ec-b3df-0242ac110002 UniProtKB:P29460 biolink:molecularly_interacts_with DrugCentral:4966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-12) DrugCentral uuid:63066c68-6b31-11ec-b3df-0242ac110002 UniProtKB:P29460 biolink:molecularly_interacts_with DrugCentral:4966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-12) DrugCentral uuid:63069f58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:4966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:63069f58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:4966 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ustekinumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:6306ce7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4967 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 golimumab is antibody binding of Cytokine (Tumor necrosis factor) DrugCentral uuid:6306f408-6b31-11ec-b3df-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4968 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 certolizumab pegol is antibody binding of Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.046']} DrugCentral uuid:63071d02-6b31-11ec-b3df-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:4969 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eculizumab is antibody binding of Secreted (Complement C5) DrugCentral uuid:630745e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P05556 biolink:molecularly_interacts_with DrugCentral:4970 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-1) DrugCentral uuid:630745e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P05556 biolink:molecularly_interacts_with DrugCentral:4970 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-1) DrugCentral uuid:630778e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4970 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) DrugCentral uuid:630778e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4970 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 natalizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) DrugCentral uuid:6307a84e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:4971 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ranibizumab is antibody binding of Secreted (Vascular endothelial growth factor A) DrugCentral uuid:6307ccfc-6b31-11ec-b3df-0242ac110002 UniProtKB:P01854 biolink:molecularly_interacts_with DrugCentral:4972 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omalizumab is antibody binding of Antibody (Ig epsilon chain C region) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.16']} DrugCentral uuid:6307f6d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide targets Enzyme (Nicotinamide phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:63081fa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P43490 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide targets Cytokine (Nicotinamide phosphoribosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:6308492a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BY41 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.135']} DrugCentral uuid:6308722e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96DB2 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.365']} DrugCentral uuid:63089b14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92769 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.796']} DrugCentral uuid:6308c4fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13547 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.022']} DrugCentral uuid:6308ee3e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15379 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.174']} DrugCentral uuid:63091738-6b31-11ec-b3df-0242ac110002 UniProtKB:Q969S8 biolink:molecularly_interacts_with DrugCentral:4973 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chidamide is inhibitor of Enzyme (Histone deacetylase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.108']} DrugCentral uuid:63094014-6b31-11ec-b3df-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4974 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infliximab is antibody binding of Cytokine (Tumor necrosis factor) DrugCentral uuid:63096544-6b31-11ec-b3df-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4975 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rituximab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.51']} DrugCentral uuid:63098eca-6b31-11ec-b3df-0242ac110002 UniProtKB:P04150 biolink:molecularly_interacts_with DrugCentral:4976 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 triamcinolone hexacetonide is agonist of Nuclear hormone receptor (Glucocorticoid receptor) DrugCentral uuid:6309b378-6b31-11ec-b3df-0242ac110002 UniProtKB:P05231 biolink:molecularly_interacts_with DrugCentral:4977 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siltuximab is antibody binding of Cytokine (Interleukin-6) DrugCentral uuid:6309d812-6b31-11ec-b3df-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:4978 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etanercept is inhibitor of Cytokine (Tumor necrosis factor) DrugCentral uuid:6309fd74-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4979 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab is antibody binding of Kinase (Receptor tyrosine-protein kinase erbB-2) DrugCentral uuid:630a2204-6b31-11ec-b3df-0242ac110002 UniProtKB:P20138 biolink:molecularly_interacts_with DrugCentral:4980 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gemtuzumab ozogamicin is antibody binding of Surface antigen (Myeloid cell surface antigen CD33) DrugCentral uuid:630a46a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4981 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin aspart is agonist of Kinase (Insulin receptor) DrugCentral uuid:630a6f3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vedolizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:630a6f3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P26010 biolink:molecularly_interacts_with DrugCentral:4982 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vedolizumab is antibody binding of Adhesion (Integrin alpha-4/beta-7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:630aa6a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4983 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obinutuzumab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) DrugCentral uuid:630acb64-6b31-11ec-b3df-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:4984 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibritumomab tiuxetan is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.854']} DrugCentral uuid:630af44a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:4985 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin detemir is agonist of Kinase (Insulin receptor) DrugCentral uuid:630b1902-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:4986 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pegfilgrastim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:630b3de2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:4987 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgrastim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:630b6268-6b31-11ec-b3df-0242ac110002 UniProtKB:P21462 biolink:molecularly_interacts_with DrugCentral:4988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deoxycholic acid is antagonist of GPCR (fMet-Leu-Phe receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4']} DrugCentral uuid:630b8b6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:4988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deoxycholic acid targets Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.35']} DrugCentral uuid:630bb42a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:4988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deoxycholic acid is agonist of GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.2']} DrugCentral uuid:630bdd88-6b31-11ec-b3df-0242ac110002 UniProtKB:P07445 biolink:molecularly_interacts_with DrugCentral:4988 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deoxycholic acid targets Unclassified (Steroid Delta-isomerase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.8']} DrugCentral uuid:630c0790-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is antibody binding of Kinase (Receptor tyrosine-protein kinase erbB-2) DrugCentral uuid:630c4aa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:630c4aa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:630c4aa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:630c4aa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:630c4aa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:630c4aa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:630c4aa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:630c4aa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:630c4aa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:4990 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab emtansine is inhibitor of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:630cc9dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:4991 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lipegfilgrastim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:630cf24a-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vonoprazan is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:630cf24a-6b31-11ec-b3df-0242ac110002 UniProtKB:P51164 biolink:molecularly_interacts_with DrugCentral:4993 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vonoprazan is inhibitor of Transporter (Potassium-transporting ATPase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:630d27d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:4995 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoetin alfa is agonist of Membrane receptor (Erythropoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11.15']} DrugCentral uuid:630d50d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:4996 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romiplostim is agonist of Membrane receptor (Thrombopoietin receptor) DrugCentral uuid:630d75a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NBP7 biolink:molecularly_interacts_with DrugCentral:5000 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evolocumab is inhibitor of Enzyme (Proprotein convertase subtilisin/kexin type 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.72']} DrugCentral uuid:630d9e70-6b31-11ec-b3df-0242ac110002 UniProtKB:P33535 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline targets GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:630dc80a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33533 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline targets GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.89']} DrugCentral uuid:630df186-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:630e1a76-6b31-11ec-b3df-0242ac110002 UniProtKB:P41144 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline is agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.26']} DrugCentral uuid:630e4488-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:630e6ddc-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:5001 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eluxadoline is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.886']} DrugCentral uuid:630e96d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5002 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin lispro is agonist of Kinase (Insulin receptor) DrugCentral uuid:630ebb70-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5003 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin human targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.74']} DrugCentral uuid:630ee47e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15127 biolink:molecularly_interacts_with DrugCentral:5003 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin human targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.71']} DrugCentral uuid:630f0d6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5003 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin human is agonist of Kinase (Insulin receptor) DrugCentral uuid:630f31f4-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:5005 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mirodenafil is inhibitor of Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.469']} DrugCentral uuid:630f5a9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BPV8 biolink:molecularly_interacts_with DrugCentral:5006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cangrelor is antagonist of GPCR (P2Y purinoceptor 13) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:630f84ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6NS65 biolink:molecularly_interacts_with DrugCentral:5006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cangrelor is antagonist of GPCR (Uracil nucleotide/cysteinyl leukotriene receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.92']} DrugCentral uuid:630faddc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H244 biolink:molecularly_interacts_with DrugCentral:5006 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cangrelor is antagonist of GPCR (P2Y purinoceptor 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.627']} DrugCentral uuid:630fd6a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5007 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoetin theta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:630ffb20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q62226 biolink:molecularly_interacts_with DrugCentral:5008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sonidegib targets Enzyme (Sonic hedgehog protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:6310255a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5008 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sonidegib is antagonist of GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.222']} DrugCentral uuid:63104e36-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecasermin targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.854']} DrugCentral uuid:6310783e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5009 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mecasermin is agonist of Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.31']} DrugCentral uuid:6310a14c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:5010 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumacaftor is pharmacological chaperone of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.456']} DrugCentral uuid:6310d23e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5011 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesleukin is agonist of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:6310d23e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5011 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesleukin is agonist of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:6310d23e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5011 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aldesleukin is agonist of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:63110ba0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08473 biolink:molecularly_interacts_with DrugCentral:5012 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sacubitril is inhibitor of Enzyme (Neprilysin) DrugCentral uuid:6311304e-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:5013 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trelagliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.398']} DrugCentral uuid:63115a2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:63118328-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:6311ac72-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.64']} DrugCentral uuid:6311d602-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.05']} DrugCentral uuid:6312014a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08588 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Beta-1 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.229']} DrugCentral uuid:63122a3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07550 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Beta-2 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.174']} DrugCentral uuid:63125316-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.796']} DrugCentral uuid:63127c1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08913 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Alpha-2A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:6312a564-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.538']} DrugCentral uuid:6312ce36-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.857']} DrugCentral uuid:6312f712-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.721']} DrugCentral uuid:63132002-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.469']} DrugCentral uuid:63134992-6b31-11ec-b3df-0242ac110002 UniProtKB:P50406 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.237']} DrugCentral uuid:63137372-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.432']} DrugCentral uuid:63139c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.42']} DrugCentral uuid:6313c69c-6b31-11ec-b3df-0242ac110002 UniProtKB:P18089 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (Alpha-2B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:6313efc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.959']} DrugCentral uuid:631418b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.721']} DrugCentral uuid:631441bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.495']} DrugCentral uuid:63146b10-6b31-11ec-b3df-0242ac110002 UniProtKB:P18825 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (Alpha-2C adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.229']} DrugCentral uuid:63149400-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.025']} DrugCentral uuid:6314bce6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.201']} DrugCentral uuid:6314e5e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.585']} DrugCentral uuid:63150f84-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.77']} DrugCentral uuid:63153874-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.854']} DrugCentral uuid:6315615a-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.523']} DrugCentral uuid:63158a5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.921']} DrugCentral uuid:6315b4a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5014 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexpiprazole is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.328']} DrugCentral uuid:6315dd88-6b31-11ec-b3df-0242ac110002 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:5015 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pegvisomant is antagonist of GPCR (Growth hormone receptor) DrugCentral uuid:63160222-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NBP7 biolink:molecularly_interacts_with DrugCentral:5016 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alirocumab is inhibitor of Enzyme (Proprotein convertase subtilisin/kexin type 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.42']} DrugCentral uuid:63162f22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPH3 biolink:molecularly_interacts_with DrugCentral:5017 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anakinra is antagonist of Membrane receptor (Interleukin-1 receptor, type I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:63162f22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPH3 biolink:molecularly_interacts_with DrugCentral:5017 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 anakinra is antagonist of Membrane receptor (Interleukin-1 receptor, type I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:63166410-6b31-11ec-b3df-0242ac110002 UniProtKB:P19327 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.93']} DrugCentral uuid:63168d6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.516']} DrugCentral uuid:6316b654-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.439']} DrugCentral uuid:6316e110-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.398']} DrugCentral uuid:63170a14-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.049']} DrugCentral uuid:631732fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.054']} DrugCentral uuid:63175cc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P47898 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin targets GPCR (5-hydroxytryptamine receptor 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.093']} DrugCentral uuid:6317867e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:6317b004-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5022 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flibanserin is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.31']} DrugCentral uuid:6317dd0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sargramostim is agonist of Membrane receptor (Granulocyte macrophage colony-stimulating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.301']} DrugCentral uuid:6317dd0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5025 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sargramostim is agonist of Membrane receptor (Granulocyte macrophage colony-stimulating factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.301']} DrugCentral uuid:6318165c-6b31-11ec-b3df-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5026 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oprelvekin is agonist of Membrane receptor (Interleukin-11 receptor) DrugCentral uuid:6318165c-6b31-11ec-b3df-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5026 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oprelvekin is agonist of Membrane receptor (Interleukin-11 receptor) DrugCentral uuid:63184564-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:5027 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rolapitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.18']} DrugCentral uuid:63186e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P51679 biolink:molecularly_interacts_with DrugCentral:5031 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mogamulizumab is antibody binding of GPCR (C-C chemokine receptor type 4) DrugCentral uuid:631892c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:6318bc56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.68']} DrugCentral uuid:6318e532-6b31-11ec-b3df-0242ac110002 UniProtKB:P21918 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(1B) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.1']} DrugCentral uuid:63190e2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.96']} DrugCentral uuid:631936f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:6319617e-6b31-11ec-b3df-0242ac110002 UniProtKB:P19020 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:63198a5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41595 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is antagonist of GPCR (5-hydroxytryptamine receptor 2B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.24']} DrugCentral uuid:6319b35e-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is antagonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.87']} DrugCentral uuid:6319dca8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.95']} DrugCentral uuid:631a0584-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is partial agonist of GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.07']} DrugCentral uuid:631a2e7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is antagonist of GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.63']} DrugCentral uuid:631a575a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25100 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine targets GPCR (Alpha-1D adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.68']} DrugCentral uuid:631a80f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is partial agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.31']} DrugCentral uuid:631aa9e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:631ad2de-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5037 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cariprazine is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.73']} DrugCentral uuid:631afbba-6b31-11ec-b3df-0242ac110002 UniProtKB:P00918 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.48']} DrugCentral uuid:631b26a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00915 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.12']} DrugCentral uuid:631b50ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P04035 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (3-hydroxy-3-methylglutaryl-coenzyme A reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:631b79a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.34']} DrugCentral uuid:631ba272-6b31-11ec-b3df-0242ac110002 UniProtKB:P05177 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Cytochrome P450 1A2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:631bcba8-6b31-11ec-b3df-0242ac110002 UniProtKB:O76074 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (cGMP-specific 3',5'-cyclic phosphodiesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:631bf470-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:631c1d56-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:631c461e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24557 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Thromboxane-A synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:631c6ffe-6b31-11ec-b3df-0242ac110002 UniProtKB:P23280 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.75']} DrugCentral uuid:631c98da-6b31-11ec-b3df-0242ac110002 UniProtKB:P27361 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Mitogen-activated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:631cc1a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:631ceb3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07943 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Aldose reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:631d14a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P12530 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Arachidonate 15-lipoxygenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:631d3d62-6b31-11ec-b3df-0242ac110002 UniProtKB:P28482 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Kinase (Mitogen-activated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.73']} DrugCentral uuid:631d6620-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2PCB5 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Enzyme (Carbonic anhydrase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.03']} DrugCentral uuid:631d90a0-6b31-11ec-b3df-0242ac110002 UniProtKB:A6XA80 biolink:molecularly_interacts_with DrugCentral:5039 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tannic acid targets Unclassified (Leukotriene C4 synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:631db972-6b31-11ec-b3df-0242ac110002 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:5042 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somatrem is agonist of GPCR (Growth hormone receptor) DrugCentral uuid:631dde02-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5044 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reteplase is activator of Enzyme (Plasminogen) DrugCentral uuid:631e0292-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobimetinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.74']} DrugCentral uuid:631e2bf0-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobimetinib is allosteric modulator of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.7']} DrugCentral uuid:631e54e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5046 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cobimetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.046']} DrugCentral uuid:631e7dda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:5047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saroglitazar is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.187']} DrugCentral uuid:631ea6de-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:5047 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 saroglitazar is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:631ed078-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:631ef95e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.94']} DrugCentral uuid:631f2244-6b31-11ec-b3df-0242ac110002 UniProtKB:P25021 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant is antagonist of GPCR (Histamine H2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.96']} DrugCentral uuid:631f4c1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9QYN8 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:631f7564-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:631f9e2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P58406 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.85']} DrugCentral uuid:631fc6ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JI35 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:631fefc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P81908 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets Enzyme (Cholinesterase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.08']} DrugCentral uuid:6320191a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.77']} DrugCentral uuid:632041d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9JI35 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant targets GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.8']} DrugCentral uuid:63206ad2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5N1 biolink:molecularly_interacts_with DrugCentral:5048 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pitolisant is inverse agonist of GPCR (Histamine H3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.796']} DrugCentral uuid:632094d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P28222 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.1']} DrugCentral uuid:6320c0c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P28221 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.2']} DrugCentral uuid:6320eca0-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.7']} DrugCentral uuid:632115c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P14842 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.7']} DrugCentral uuid:63213f3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32305 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:63216838-6b31-11ec-b3df-0242ac110002 UniProtKB:P30729 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is antagonist of GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.3']} DrugCentral uuid:6321910a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31388 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is agonist of GPCR (5-hydroxytryptamine receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.8']} DrugCentral uuid:6321b9fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.824']} DrugCentral uuid:6321e344-6b31-11ec-b3df-0242ac110002 UniProtKB:P34969 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (5-hydroxytryptamine receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.409']} DrugCentral uuid:63220c2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35462 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (D(3) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:6322352e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35367 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (Histamine H1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.215']} DrugCentral uuid:63225e1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.357']} DrugCentral uuid:63228aba-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is partial agonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.469']} DrugCentral uuid:6322b47c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is partial agonist of GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.77']} DrugCentral uuid:6322de48-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5052 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 aripiprazole lauroxil is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.469']} DrugCentral uuid:632307f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omarigliptin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.41']} DrugCentral uuid:632330aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P28843 biolink:molecularly_interacts_with DrugCentral:5054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omarigliptin targets Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.36']} DrugCentral uuid:63235a80-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:5054 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omarigliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.097']} DrugCentral uuid:6323835c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5057 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 insulin glulisine is agonist of Kinase (Insulin receptor) DrugCentral uuid:6323a86e-6b31-11ec-b3df-0242ac110002 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:5059 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lusutrombopag is agonist of Membrane receptor (Thrombopoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.076']} DrugCentral uuid:6323d12c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:5060 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esflurbiprofen targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:6323fa08-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63921 biolink:molecularly_interacts_with DrugCentral:5060 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 esflurbiprofen targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:632422e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:5061 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mepolizumab is antibody binding of Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10']} DrugCentral uuid:63244f1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.79']} DrugCentral uuid:632477ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:6324a0ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:6324c992-6b31-11ec-b3df-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:6324f304-6b31-11ec-b3df-0242ac110002 UniProtKB:P53634 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Enzyme (Dipeptidyl peptidase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.48']} DrugCentral uuid:63251bf4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.75']} DrugCentral uuid:632544e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5062 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osimertinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:63256dca-6b31-11ec-b3df-0242ac110002 UniProtKB:P28907 biolink:molecularly_interacts_with DrugCentral:5063 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daratumumab is antibody binding of Tumour-associated antigen (Lymphocyte differentiation antigen CD38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.22']} DrugCentral uuid:6325978c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:5064 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 climbazole targets Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:6325c0c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:5065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trenbolone hexahydrobenzylcarbonate targets Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:6325e994-6b31-11ec-b3df-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:5065 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trenbolone hexahydrobenzylcarbonate targets Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['4.04']} DrugCentral uuid:63261342-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5066 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenecteplase is activator of Enzyme (Plasminogen) DrugCentral uuid:632637c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P20618 biolink:molecularly_interacts_with DrugCentral:5067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixazomib is inhibitor of Enzyme (Proteasome subunit beta type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.509']} DrugCentral uuid:632660a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P49721 biolink:molecularly_interacts_with DrugCentral:5067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixazomib is inhibitor of Enzyme (Proteasome subunit beta type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.456']} DrugCentral uuid:6326898a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28074 biolink:molecularly_interacts_with DrugCentral:5067 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixazomib is inhibitor of Enzyme (Proteasome subunit beta type-5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.469']} DrugCentral uuid:6326b324-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02563 biolink:molecularly_interacts_with DrugCentral:5068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivaracetam is inhibitor of Unclassified (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:6326dc14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7L0J3 biolink:molecularly_interacts_with DrugCentral:5068 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brivaracetam is modulator of Transporter (Synaptic vesicle glycoprotein 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.1']} DrugCentral uuid:6327052c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5071 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 necitumumab is antibody binding of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.49']} DrugCentral uuid:63272e12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NQ25 biolink:molecularly_interacts_with DrugCentral:5072 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elotuzumab is antibody binding of Membrane receptor (SLAM family member 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.05']} DrugCentral uuid:6327586a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSA0 biolink:molecularly_interacts_with DrugCentral:5075 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lesinurad is inhibitor of Transporter (Solute carrier family 22 member 11) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.432']} DrugCentral uuid:632781e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:5075 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lesinurad is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.137']} DrugCentral uuid:6327aaae-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:6327d380-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:6327fe1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13258 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag targets GPCR (Prostaglandin D2 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:632826e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43253 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.68']} DrugCentral uuid:63284fcc-6b31-11ec-b3df-0242ac110002 UniProtKB:P35408 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP4 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.31']} DrugCentral uuid:632878c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.24']} DrugCentral uuid:6328a27e-6b31-11ec-b3df-0242ac110002 UniProtKB:P43119 biolink:molecularly_interacts_with DrugCentral:5077 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selexipag is agonist of GPCR (Prostacyclin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.699']} DrugCentral uuid:6328cb78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:5078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lobeglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.699']} DrugCentral uuid:6328f472-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:5078 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lobeglitazone is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.745']} DrugCentral uuid:63291da8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:63294670-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.7']} DrugCentral uuid:63296f42-6b31-11ec-b3df-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.523']} DrugCentral uuid:63299828-6b31-11ec-b3df-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:6329c294-6b31-11ec-b3df-0242ac110002 UniProtKB:O39929 biolink:molecularly_interacts_with DrugCentral:5080 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elbasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.523']} DrugCentral uuid:6329ebb6-6b31-11ec-b3df-0242ac110002 UniProtKB:A3EZI9 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir targets Enzyme (NS3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.4']} DrugCentral uuid:632a149c-6b31-11ec-b3df-0242ac110002 UniProtKB:K7XJL6 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir targets Unclassified (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.85']} DrugCentral uuid:632a3d8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q0ZMF1 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir targets Unclassified (NS3 protease) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.15']} DrugCentral uuid:632a671c-6b31-11ec-b3df-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.301']} DrugCentral uuid:632a8ff8-6b31-11ec-b3df-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.398']} DrugCentral uuid:632ab8e8-6b31-11ec-b3df-0242ac110002 UniProtKB:O39929 biolink:molecularly_interacts_with DrugCentral:5081 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 grazoprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['12.523']} DrugCentral uuid:632ae1c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16552 biolink:molecularly_interacts_with DrugCentral:5083 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ixekizumab is antibody binding of Cytokine (Interleukin-17A) DrugCentral uuid:632b0e6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5087 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denileukin diftitox is antibody binding of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:632b0e6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5087 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denileukin diftitox is antibody binding of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:632b0e6a-6b31-11ec-b3df-0242ac110002 UniProtKB:P31785 biolink:molecularly_interacts_with DrugCentral:5087 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 denileukin diftitox is antibody binding of Membrane receptor (Interleukin-2 receptor) DrugCentral uuid:632b4a4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P06729 biolink:molecularly_interacts_with DrugCentral:5088 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alefacept is inhibitor of Surface antigen (T-cell surface antigen CD2) DrugCentral uuid:632b6ee6-6b31-11ec-b3df-0242ac110002 UniProtKB:P33681 biolink:molecularly_interacts_with DrugCentral:5089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD80) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:632b9998-6b31-11ec-b3df-0242ac110002 UniProtKB:P42081 biolink:molecularly_interacts_with DrugCentral:5089 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD86) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:632bc4c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P33681 biolink:molecularly_interacts_with DrugCentral:5091 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD80) DrugCentral uuid:632be95c-6b31-11ec-b3df-0242ac110002 UniProtKB:P42081 biolink:molecularly_interacts_with DrugCentral:5091 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belatacept is inhibitor of Surface antigen (T-lymphocyte activation antigen CD86) DrugCentral uuid:632c0e82-6b31-11ec-b3df-0242ac110002 UniProtKB:P05113 biolink:molecularly_interacts_with DrugCentral:5093 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 reslizumab is antibody binding of Cytokine (Interleukin-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.092']} DrugCentral uuid:632c383a-6b31-11ec-b3df-0242ac110002 UniProtKB:P13423 biolink:molecularly_interacts_with DrugCentral:5094 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obiltoxaximab is antibody binding of Secreted (Protective antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.481']} DrugCentral uuid:632c6116-6b31-11ec-b3df-0242ac110002 UniProtKB:P01583 biolink:molecularly_interacts_with DrugCentral:5105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilonacept is inhibitor of Cytokine (Interleukin-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.854']} DrugCentral uuid:632c8a24-6b31-11ec-b3df-0242ac110002 UniProtKB:P18510 biolink:molecularly_interacts_with DrugCentral:5105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilonacept is inhibitor of Unclassified (Interleukin-1 receptor antagonist protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.215']} DrugCentral uuid:632cb30a-6b31-11ec-b3df-0242ac110002 UniProtKB:P01584 biolink:molecularly_interacts_with DrugCentral:5105 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rilonacept is inhibitor of Cytokine (Interleukin-1 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['12.301']} DrugCentral uuid:632cdc7c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5109 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 urokinase is activator of Enzyme (Plasminogen) DrugCentral uuid:632d00f8-6b31-11ec-b3df-0242ac110002 UniProtKB:O43451 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Maltase-glucoamylase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:632d29b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P10253 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Lysosomal alpha-glucosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.22']} DrugCentral uuid:632d5274-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HCG7 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Non-lysosomal glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4']} DrugCentral uuid:632d7cea-6b31-11ec-b3df-0242ac110002 UniProtKB:P14410 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Sucrase-isomaltase, intestinal) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:632da5b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35573 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Glycogen debranching enzyme) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5']} DrugCentral uuid:632dce7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P09848 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Lactase-phlorizin hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.3']} DrugCentral uuid:632df756-6b31-11ec-b3df-0242ac110002 UniProtKB:P16278 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.05']} DrugCentral uuid:632e20c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59750 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.9']} DrugCentral uuid:632e4990-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02401 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Lactase-phlorizin hydrolase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.14']} DrugCentral uuid:632e724e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UUZ4 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Alpha-galactosidase C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.74']} DrugCentral uuid:632e9b7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q42656 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Alpha-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:632ec442-6b31-11ec-b3df-0242ac110002 UniProtKB:D3ZUM4 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.62']} DrugCentral uuid:632eed00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8VNN2 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat targets Enzyme (Beta-galactosidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.89']} DrugCentral uuid:632f15fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P06280 biolink:molecularly_interacts_with DrugCentral:5110 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 migalastat is pharmacological chaperone of Enzyme (Alpha-galactosidase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:632f40a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chromic chloride targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:632f696a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5118 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 chromic chloride targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:632f9246-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07817 biolink:molecularly_interacts_with DrugCentral:5133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venetoclax is inhibitor of Cytosolic other (Bcl-2-like protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.319']} DrugCentral uuid:632fbb36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92843 biolink:molecularly_interacts_with DrugCentral:5133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venetoclax is inhibitor of Cytosolic other (Apoptosis regulator Bcl-W) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.611']} DrugCentral uuid:632fe4da-6b31-11ec-b3df-0242ac110002 UniProtKB:P10415 biolink:molecularly_interacts_with DrugCentral:5133 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 venetoclax is inhibitor of Cytosolic other (Apoptosis regulator Bcl-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['11']} DrugCentral uuid:633011a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:633011a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5137 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:63304498-6b31-11ec-b3df-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 interferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:63304498-6b31-11ec-b3df-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5139 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 interferon beta-1a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:633077d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 interferon beta-1b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:633077d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5140 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 interferon beta-1b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:6330a6d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00747 biolink:molecularly_interacts_with DrugCentral:5141 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alteplase is activator of Enzyme (Plasminogen) DrugCentral uuid:6330cb70-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimavanserin is inverse agonist of GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.8']} DrugCentral uuid:6330f46a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5142 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pimavanserin is inverse agonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.3']} DrugCentral uuid:63311f4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P22734 biolink:molecularly_interacts_with DrugCentral:5143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opicapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:633149c4-6b31-11ec-b3df-0242ac110002 UniProtKB:O88587 biolink:molecularly_interacts_with DrugCentral:5143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opicapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.82']} DrugCentral uuid:633172a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P21964 biolink:molecularly_interacts_with DrugCentral:5143 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 opicapone is inhibitor of Enzyme (Catechol O-methyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9']} DrugCentral uuid:63319b72-6b31-11ec-b3df-0242ac110002 UniProtKB:P04062 biolink:molecularly_interacts_with DrugCentral:5144 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gluconolactone targets Enzyme (Glucosylceramidase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.52']} DrugCentral uuid:6331c52a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22888 biolink:molecularly_interacts_with DrugCentral:5149 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 choriogonadotropin alfa is agonist of GPCR (Lutropin-choriogonadotropic hormone receptor) DrugCentral uuid:6331e9c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZQ7 biolink:molecularly_interacts_with DrugCentral:5151 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atezolizumab is antibody binding of CD molecules (Programmed cell death 1 ligand 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.39']} DrugCentral uuid:633212aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:63323c12-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:63326570-6b31-11ec-b3df-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.796']} DrugCentral uuid:63328e4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P27958 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.854']} DrugCentral uuid:6332b728-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99IB8 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.979']} DrugCentral uuid:6332e0e0-6b31-11ec-b3df-0242ac110002 UniProtKB:O39929 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.046']} DrugCentral uuid:63330ac0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q81495 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:6333339c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9DHD6 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.398']} DrugCentral uuid:63335c8c-6b31-11ec-b3df-0242ac110002 UniProtKB:O91936 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.426']} DrugCentral uuid:6333861c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5I2N3 biolink:molecularly_interacts_with DrugCentral:5154 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 velpatasvir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11.097']} DrugCentral uuid:6333aeda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDU6 biolink:molecularly_interacts_with DrugCentral:5155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obeticholic acid targets GPCR (G-protein coupled bile acid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7']} DrugCentral uuid:6333d7a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RI1 biolink:molecularly_interacts_with DrugCentral:5155 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 obeticholic acid is agonist of Nuclear hormone receptor (Bile acid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.004']} DrugCentral uuid:63340074-6b31-11ec-b3df-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5157 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darbepoetin alfa is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:63342964-6b31-11ec-b3df-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon alfa-2a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:63342964-6b31-11ec-b3df-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5158 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon alfa-2a is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:6334586c-6b31-11ec-b3df-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5160 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoetin beta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:633480da-6b31-11ec-b3df-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon alfa-2b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:633480da-6b31-11ec-b3df-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5164 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 peginterferon alfa-2b is agonist of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:6334afe2-6b31-11ec-b3df-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5165 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 methoxy polyethylene glycol-epoetin beta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:6334d6e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99062 biolink:molecularly_interacts_with DrugCentral:5167 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lenograstim is activator of Membrane receptor (Granulocyte colony-stimulating factor receptor) DrugCentral uuid:6334fbdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P11473 biolink:molecularly_interacts_with DrugCentral:5169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eldecalcitol is agonist of Nuclear hormone receptor (Vitamin D3 receptor) DrugCentral uuid:6335206c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13053 biolink:molecularly_interacts_with DrugCentral:5169 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eldecalcitol is agonist of Transcription factor (Vitamin D3 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:63354966-6b31-11ec-b3df-0242ac110002 UniProtKB:P19235 biolink:molecularly_interacts_with DrugCentral:5170 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 epoetin zeta is agonist of Membrane receptor (Erythropoietin receptor) DrugCentral uuid:63356e82-6b31-11ec-b3df-0242ac110002 UniProtKB:P05362 biolink:molecularly_interacts_with DrugCentral:5174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lifitegrast targets Unclassified (Intercellular adhesion molecule 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.53']} DrugCentral uuid:63359b46-6b31-11ec-b3df-0242ac110002 UniProtKB:P05107 biolink:molecularly_interacts_with DrugCentral:5174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lifitegrast is antagonist of Adhesion (Integrin alpha-L/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.046']} DrugCentral uuid:63359b46-6b31-11ec-b3df-0242ac110002 UniProtKB:P05107 biolink:molecularly_interacts_with DrugCentral:5174 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lifitegrast is antagonist of Adhesion (Integrin alpha-L/beta-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.046']} DrugCentral uuid:6335d7e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:5177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 muromonab-CD3 is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) DrugCentral uuid:6335d7e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:5177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 muromonab-CD3 is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) DrugCentral uuid:6335d7e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P04234 biolink:molecularly_interacts_with DrugCentral:5177 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 muromonab-CD3 is antibody binding of Surface antigen (T-cell surface glycoprotein CD3) DrugCentral uuid:633615c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NAC3 biolink:molecularly_interacts_with DrugCentral:5179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodalumab is antibody binding of Membrane receptor (Interleukin-17 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:633615c6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NAC3 biolink:molecularly_interacts_with DrugCentral:5179 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brodalumab is antibody binding of Membrane receptor (Interleukin-17 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.2']} DrugCentral uuid:63364ac8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:5181 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etelcalcetide is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.6']} DrugCentral uuid:633673a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5182 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eteplirsen is binding agent of RNA (exon 51 of dystrophin pre-mRNA) DrugCentral uuid:63369b4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5183 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olaratumab is antibody binding of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.4']} DrugCentral uuid:6336c49e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:5185 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallium (68Ga) edotreotide is antagonist of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:6336ee24-6b31-11ec-b3df-0242ac110002 UniProtKB:P18177 biolink:molecularly_interacts_with DrugCentral:5186 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bezlotoxumab is antibody binding of Enzyme (Toxin B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:6337173c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5188 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 radotinib is inhibitor of Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.514']} DrugCentral uuid:633740ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P54750 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole targets Enzyme (Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:63376ab6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13946 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole targets Enzyme (High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.14']} DrugCentral uuid:63379efa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:63379efa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:63379efa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:63379efa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08499 biolink:molecularly_interacts_with DrugCentral:5201 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crisaborole is inhibitor of Enzyme (Phosphodiesterase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:6337ec2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.1']} DrugCentral uuid:6338151a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:63383e00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:633867d6-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.87']} DrugCentral uuid:633890b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.276']} DrugCentral uuid:6338b9a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.229']} DrugCentral uuid:6338e292-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5202 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baricitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.244']} DrugCentral uuid:63390c04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:633934d6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95271 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Tankyrase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.84']} DrugCentral uuid:63395dbc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKK3 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.08']} DrugCentral uuid:6339868e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q53GL7 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.25']} DrugCentral uuid:6339afce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0J9 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:6339d8b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q460N5 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.05']} DrugCentral uuid:633a019a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q460N3 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.49']} DrugCentral uuid:633a2a80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:633a5776-6b31-11ec-b3df-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.5']} DrugCentral uuid:633a8066-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6F1 biolink:molecularly_interacts_with DrugCentral:5203 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rucaparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:633aa956-6b31-11ec-b3df-0242ac110002 UniProtKB:P01375 biolink:molecularly_interacts_with DrugCentral:5208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plecanatide targets Cytokine (Tumor necrosis factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.42']} DrugCentral uuid:633ad2c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19438 biolink:molecularly_interacts_with DrugCentral:5208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plecanatide targets Unclassified (Tumor necrosis factor receptor superfamily member 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.66']} DrugCentral uuid:633afb9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P25092 biolink:molecularly_interacts_with DrugCentral:5208 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 plecanatide is agonist of Enzyme (Heat-stable enterotoxin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.721']} DrugCentral uuid:633b2476-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5209 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 icotinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.699']} DrugCentral uuid:633b4d52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olmutinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:633b7688-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5210 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 olmutinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.036']} DrugCentral uuid:633b9f64-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.28']} DrugCentral uuid:633bc84a-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.368']} DrugCentral uuid:633bf13a-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.276']} DrugCentral uuid:633c1b74-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.886']} DrugCentral uuid:633c445a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5211 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apatinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:633c6e26-6b31-11ec-b3df-0242ac110002 UniProtKB:P17752 biolink:molecularly_interacts_with DrugCentral:5214 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 telotristat ethyl is inhibitor of Enzyme (Tryptophan 5-hydroxylase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:633c970c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclabuvir targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.61']} DrugCentral uuid:633cc0ba-6b31-11ec-b3df-0242ac110002 UniProtKB:O39930 biolink:molecularly_interacts_with DrugCentral:5215 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 beclabuvir targets Unclassified (RNA-directed RNA polymerase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.72']} DrugCentral uuid:633ce996-6b31-11ec-b3df-0242ac110002 UniProtKB:P36544 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.85']} DrugCentral uuid:633d1290-6b31-11ec-b3df-0242ac110002 UniProtKB:P02718 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Acetylcholine receptor subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:633d3b6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P09483 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.47']} DrugCentral uuid:633d64d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05941 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Neuronal acetylcholine receptor subunit alpha-7) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.05']} DrugCentral uuid:633d8dc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P02710 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Acetylcholine receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:633db6b4-6b31-11ec-b3df-0242ac110002 UniProtKB:A9XFY4 biolink:molecularly_interacts_with DrugCentral:5217 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cytisine targets Ion channel (Nicotinic acetylcholine receptor alpha 5 subunit) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.91']} DrugCentral uuid:633de31e-6b31-11ec-b3df-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:5218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribociclib targets Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.12']} DrugCentral uuid:633e0ea2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:5218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribociclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.409']} DrugCentral uuid:633e3882-6b31-11ec-b3df-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5218 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ribociclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:633e615e-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:5220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naldemedine is antagonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.04']} DrugCentral uuid:633e8b02-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5220 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 naldemedine is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.95']} DrugCentral uuid:633eb3e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZQ7 biolink:molecularly_interacts_with DrugCentral:5221 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avelumab is antibody binding of CD molecules (Programmed cell death 1 ligand 1) DrugCentral uuid:633ed86e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.29']} DrugCentral uuid:633f0136-6b31-11ec-b3df-0242ac110002 UniProtKB:O95271 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Tankyrase-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.24']} DrugCentral uuid:633f2a76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6F1 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.89']} DrugCentral uuid:633f5348-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKK3 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.48']} DrugCentral uuid:633f7c38-6b31-11ec-b3df-0242ac110002 UniProtKB:Q53GL7 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:633fa514-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0J9 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:633fcf80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q460N5 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.76']} DrugCentral uuid:633ff92e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q460N3 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib targets Enzyme (Poly [ADP-ribose] polymerase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:6340220a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.68']} DrugCentral uuid:63404adc-6b31-11ec-b3df-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5222 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 niraparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.42']} DrugCentral uuid:634074b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11836 biolink:molecularly_interacts_with DrugCentral:5223 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ocrelizumab is antibody binding of Surface antigen (B-lymphocyte antigen CD20) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.08']} DrugCentral uuid:63409e4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P24394 biolink:molecularly_interacts_with DrugCentral:5224 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dupilumab is antibody binding of Membrane receptor (Interleukin-4 receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['11.06']} DrugCentral uuid:6340c91c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:5226 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 deutetrabenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) DrugCentral uuid:6340eeb0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01827 biolink:molecularly_interacts_with DrugCentral:5227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valbenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.73']} DrugCentral uuid:634117b4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05940 biolink:molecularly_interacts_with DrugCentral:5227 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 valbenazine is inhibitor of Transporter (Synaptic vesicular amine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.523']} DrugCentral uuid:6341407c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8T9Z7 biolink:molecularly_interacts_with DrugCentral:5229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 forodesine targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.07']} DrugCentral uuid:6341696c-6b31-11ec-b3df-0242ac110002 UniProtKB:P55859 biolink:molecularly_interacts_with DrugCentral:5229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 forodesine targets Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.64']} DrugCentral uuid:634193b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P00491 biolink:molecularly_interacts_with DrugCentral:5229 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 forodesine is inhibitor of Enzyme (Purine nucleoside phosphorylase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.143']} DrugCentral uuid:6341bc82-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:6341e572-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:63420e44-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:63423932-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:6342620e-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.06']} DrugCentral uuid:63428ad6-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:6342b3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:6342dd7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:6343065a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:63432f2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:63435808-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:63438224-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:6343aad8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:6343d3c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:6343fdbc-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:63442698-6b31-11ec-b3df-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:63444fec-6b31-11ec-b3df-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:634478be-6b31-11ec-b3df-0242ac110002 UniProtKB:P11309 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase pim-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:6344a1e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:6344cbfc-6b31-11ec-b3df-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:6344f500-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:63451dbe-6b31-11ec-b3df-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:63454820-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:634570e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:634599ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:6345c2b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:6345ebfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:634614d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:63463e9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:634667c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:634690a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05655 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C delta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:6346b980-6b31-11ec-b3df-0242ac110002 UniProtKB:P22694 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:6346e2de-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:63470d72-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:63473996-6b31-11ec-b3df-0242ac110002 UniProtKB:P17252 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C alpha type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:634762d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:63478ba8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.44']} DrugCentral uuid:6347b510-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:6347ddf6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:634806dc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:63482fb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:6348590c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:634881e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:6348aae2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:6348d3d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:6348fdee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:634926c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:63494f92-6b31-11ec-b3df-0242ac110002 UniProtKB:P24723 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C eta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:634978c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:6349a190-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:6349ca80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.7']} DrugCentral uuid:6349f35c-6b31-11ec-b3df-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:634a1d78-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:634a464a-6b31-11ec-b3df-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:634a6f1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:634a980c-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:634ac1b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:634aea8c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:634b134a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:634b3c08-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:634b657a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.03']} DrugCentral uuid:634b8f82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04759 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein kinase C theta type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:634bb85e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:634be16c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:634c0aac-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:634c3392-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:634c5c50-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:634c864e-6b31-11ec-b3df-0242ac110002 UniProtKB:P31749 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (RAC-alpha serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:634cb27c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:634cdd2e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P1W9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase pim-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:634d05f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:634d2f9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:634d586c-6b31-11ec-b3df-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:634d8148-6b31-11ec-b3df-0242ac110002 UniProtKB:P49761 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.44']} DrugCentral uuid:634daaa6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:634dd3e6-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:634dfcae-6b31-11ec-b3df-0242ac110002 UniProtKB:P49841 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Glycogen synthase kinase-3 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:634e2684-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:634e4f6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:634e7ae4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:634ea3c0-6b31-11ec-b3df-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:634ecc9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:634ef618-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:634f1ef4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:634f47e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:634f70b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:634f99f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.68']} DrugCentral uuid:634fc2c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:634feba4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:6350146c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:63503e38-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:63506714-6b31-11ec-b3df-0242ac110002 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:63508ffa-6b31-11ec-b3df-0242ac110002 UniProtKB:O15530 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (3-phosphoinositide-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:6350b8cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.59']} DrugCentral uuid:6350e216-6b31-11ec-b3df-0242ac110002 UniProtKB:P49840 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Glycogen synthase kinase-3 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:63510af2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:635133c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:63515ca0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:63518612-6b31-11ec-b3df-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:6351af02-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16513 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase N2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:6351d7d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P31751 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (RAC-beta serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.11']} DrugCentral uuid:635202c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:63522cac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:63525592-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:63527f9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.08']} DrugCentral uuid:6352a8d0-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:6352d198-6b31-11ec-b3df-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:6352fa7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:63532364-6b31-11ec-b3df-0242ac110002 UniProtKB:O75914 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PAK 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:63534cfe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:635375ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:63539f38-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:6353c814-6b31-11ec-b3df-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:6353f1d6-6b31-11ec-b3df-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:63541ab2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.18']} DrugCentral uuid:63544398-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:63546cf6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:6354962c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:6354befe-6b31-11ec-b3df-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:6354e7e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:6355116a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:63553a46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:63556322-6b31-11ec-b3df-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:63558bf4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:6355b624-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:6355dffa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:635608cc-6b31-11ec-b3df-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:635631d0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:63565b24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:635683ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:6356acbe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:6356d59a-6b31-11ec-b3df-0242ac110002 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:6356ff2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:635727f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y243 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (RAC-gamma serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:635750e2-6b31-11ec-b3df-0242ac110002 UniProtKB:O95835 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase LATS1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:635779be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:6357a34e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:6357cc20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:6357f506-6b31-11ec-b3df-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:63581e46-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86V86 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase pim-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.25']} DrugCentral uuid:63584722-6b31-11ec-b3df-0242ac110002 UniProtKB:P17612 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:63586ff4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:635898da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.21']} DrugCentral uuid:6358c238-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:6358eb0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDC3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase BRSK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:635913dc-6b31-11ec-b3df-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:63593de4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:63596788-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:63599082-6b31-11ec-b3df-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:6359b954-6b31-11ec-b3df-0242ac110002 UniProtKB:P52564 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity mitogen-activated protein kinase kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:6359e348-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:635a0c88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:635a3564-6b31-11ec-b3df-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:635a5e40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:635a882a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.77']} DrugCentral uuid:635ab1b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:635ada8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:635b03f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:635b2e10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IWQ3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase BRSK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:635b58c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:635b8194-6b31-11ec-b3df-0242ac110002 UniProtKB:P68370 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Structural (Tubulin alpha-1A chain) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:635baa52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:635bd39c-6b31-11ec-b3df-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:635bfcfa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.13']} DrugCentral uuid:635c25e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:635c4ebc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.37']} DrugCentral uuid:635c782e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:635ca11e-6b31-11ec-b3df-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.59']} DrugCentral uuid:635cca04-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:635cf2fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:635d1c7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.03']} DrugCentral uuid:635d4556-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13627 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:635d6e32-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:635d9704-6b31-11ec-b3df-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:635dc03a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15835 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Rhodopsin kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:635dea2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.96']} DrugCentral uuid:635e130a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.32']} DrugCentral uuid:635e3c86-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:635e6558-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:635e8e3e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:635eb724-6b31-11ec-b3df-0242ac110002 UniProtKB:P57058 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Hormonally up-regulated neu tumor-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:635ee1e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:635f0b3e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:635f3424-6b31-11ec-b3df-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:635f5d00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:635f8636-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:635faf1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:635fd802-6b31-11ec-b3df-0242ac110002 UniProtKB:O43172 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Nuclear other (U4/U6 small nuclear ribonucleoprotein Prp4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:636000de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:63602b9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:63605480-6b31-11ec-b3df-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:63607d84-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:6360a764-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.82']} DrugCentral uuid:6360d0e0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Enzyme (Tankyrase-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:6360f9c6-6b31-11ec-b3df-0242ac110002 UniProtKB:O00750 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:63612298-6b31-11ec-b3df-0242ac110002 UniProtKB:O75747 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:63614bce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:636174aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WU08 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase 32A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:63619d90-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.26']} DrugCentral uuid:6361c766-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:6361f0f6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:63621a54-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.75']} DrugCentral uuid:6362433a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:63626c2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:6362960a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13976 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cGMP-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:6362bedc-6b31-11ec-b3df-0242ac110002 UniProtKB:P51817 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (cAMP-dependent protein kinase catalytic subunit PRKX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:6362e826-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06418 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin targets Kinase (Tyrosine-protein kinase receptor TYRO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:63631120-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5231 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 midostaurin is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.96']} DrugCentral uuid:63633a74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03431 biolink:molecularly_interacts_with DrugCentral:5232 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abaloparatide is agonist of GPCR (Parathyroid hormone/parathyroid hormone-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:63636346-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.174']} DrugCentral uuid:63638c22-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:6363b5bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.137']} DrugCentral uuid:6363deb6-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.796']} DrugCentral uuid:63640788-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.721']} DrugCentral uuid:63643082-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5233 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brigatinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.222']} DrugCentral uuid:63645a76-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZQ7 biolink:molecularly_interacts_with DrugCentral:5234 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 durvalumab is antibody binding of CD molecules (Programmed cell death 1 ligand 1) DrugCentral uuid:63647f06-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5235 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenegermin is agonist of Kinase (High affinity nerve growth factor receptor) DrugCentral uuid:6364a3a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08138 biolink:molecularly_interacts_with DrugCentral:5235 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenegermin is agonist of Membrane receptor (Tumor necrosis factor receptor superfamily member 16) DrugCentral uuid:6364cc22-6b31-11ec-b3df-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarilumab is antibody binding of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.1']} DrugCentral uuid:6364cc22-6b31-11ec-b3df-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5237 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sarilumab is antibody binding of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.1']} DrugCentral uuid:6365016a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evogliptin targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.1']} DrugCentral uuid:63652a5a-6b31-11ec-b3df-0242ac110002 UniProtKB:P27487 biolink:molecularly_interacts_with DrugCentral:5239 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evogliptin is inhibitor of Enzyme (Dipeptidyl peptidase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.046']} DrugCentral uuid:63655336-6b31-11ec-b3df-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:5240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polmacoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:63657c12-6b31-11ec-b3df-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:5240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polmacoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:6365a75a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23219 biolink:molecularly_interacts_with DrugCentral:5240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polmacoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.081']} DrugCentral uuid:6365d054-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:5240 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polmacoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.081']} DrugCentral uuid:6365f926-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betrixaban targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.75']} DrugCentral uuid:63662220-6b31-11ec-b3df-0242ac110002 UniProtKB:P00734 biolink:molecularly_interacts_with DrugCentral:5241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betrixaban targets Enzyme (Prothrombin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.75']} DrugCentral uuid:63664bce-6b31-11ec-b3df-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:5241 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 betrixaban is inhibitor of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.824']} DrugCentral uuid:636674b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P26663 biolink:molecularly_interacts_with DrugCentral:5242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxilaprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.42']} DrugCentral uuid:63669db8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q81495 biolink:molecularly_interacts_with DrugCentral:5242 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxilaprevir is inhibitor of Polyprotein (Genome polyprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.18']} DrugCentral uuid:6366c856-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5L478 biolink:molecularly_interacts_with DrugCentral:5244 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pibrentasvir targets Unclassified (Nonstructural protein 5A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.19']} DrugCentral uuid:6366f128-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WMX2 biolink:molecularly_interacts_with DrugCentral:5244 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pibrentasvir targets Unclassified (Genome polyprotein [Cleaved into: Core protein p21) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:636719f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P23945 biolink:molecularly_interacts_with DrugCentral:5245 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 corifollitropin alfa is agonist of GPCR (Follicle-stimulating hormone receptor) DrugCentral uuid:63674326-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5246 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guselkumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:63674326-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5246 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 guselkumab is antibody binding of Cytokine (Interleukin-23) DrugCentral uuid:636772e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P20273 biolink:molecularly_interacts_with DrugCentral:5247 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inotuzumab ozogamicin is antibody binding of Membrane receptor (B-cell receptor CD22) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:63679bc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P37231 biolink:molecularly_interacts_with DrugCentral:5248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.959']} DrugCentral uuid:6367c49a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q03181 biolink:molecularly_interacts_with DrugCentral:5248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.801']} DrugCentral uuid:6367ed6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07869 biolink:molecularly_interacts_with DrugCentral:5248 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemafibrate is agonist of Nuclear hormone receptor (Peroxisome proliferator-activated receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9']} DrugCentral uuid:6368171a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05769 biolink:molecularly_interacts_with DrugCentral:5250 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imrecoxib targets Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.75']} DrugCentral uuid:63683fec-6b31-11ec-b3df-0242ac110002 UniProtKB:P22437 biolink:molecularly_interacts_with DrugCentral:5250 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imrecoxib targets Enzyme (Prostaglandin G/H synthase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:636868be-6b31-11ec-b3df-0242ac110002 UniProtKB:P35354 biolink:molecularly_interacts_with DrugCentral:5250 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imrecoxib is inhibitor of Enzyme (Prostaglandin G/H synthase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.824']} DrugCentral uuid:636891ae-6b31-11ec-b3df-0242ac110002 UniProtKB:O75874 biolink:molecularly_interacts_with DrugCentral:5251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enasidenib targets Enzyme (Isocitrate dehydrogenase [NADP] cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:6368baf8-6b31-11ec-b3df-0242ac110002 UniProtKB:O75874 biolink:molecularly_interacts_with DrugCentral:5251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enasidenib targets Enzyme (Isocitrate dehydrogenase [NADP] cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.3']} DrugCentral uuid:6368e3de-6b31-11ec-b3df-0242ac110002 UniProtKB:P48735 biolink:molecularly_interacts_with DrugCentral:5251 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enasidenib is inhibitor of Enzyme (Isocitrate dehydrogenase [NADP], mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:63690cb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:6369362c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.08']} DrugCentral uuid:63695f1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:636988f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:6369b1c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:6369db54-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:636a043a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:636a2d20-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:636a55f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:636a7f46-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:636aa822-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:636ad126-6b31-11ec-b3df-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:636af9f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:636b2338-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:636b4c1e-6b31-11ec-b3df-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:636b7504-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:636b9dc2-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:636bc982-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:636bf25e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:636c1b44-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:636c44d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:636c6edc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:636c97b8-6b31-11ec-b3df-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:636cc09e-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:636ce9e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:636d12ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.47']} DrugCentral uuid:636d3baa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:636d6512-6b31-11ec-b3df-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:636d9276-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:636dbb70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:636de442-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.19']} DrugCentral uuid:636e0d0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:636e36c2-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.6']} DrugCentral uuid:636e5f9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.25']} DrugCentral uuid:636e8884-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:636eb1e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13043 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:636edabe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:636f039a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:636f2c80-6b31-11ec-b3df-0242ac110002 UniProtKB:O14733 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:636f5624-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.85']} DrugCentral uuid:636f7f00-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.59']} DrugCentral uuid:636fa7d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:636fd0a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:636ff9e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:637022b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15139 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase D1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:63704b92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13188 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.24']} DrugCentral uuid:63707478-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:63709dcc-6b31-11ec-b3df-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:6370c69e-6b31-11ec-b3df-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:6370ef70-6b31-11ec-b3df-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.92']} DrugCentral uuid:63711842-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:637142c2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:63716b9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P78368 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Casein kinase I isoform gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.18']} DrugCentral uuid:63719592-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6M4 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Casein kinase I isoform gamma-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:6371bf36-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:6371e81c-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.32']} DrugCentral uuid:6372112a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:63723a4c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:6372638c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:63728c68-6b31-11ec-b3df-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:6372b54e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.48']} DrugCentral uuid:6372de20-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:637308be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.03']} DrugCentral uuid:63733186-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:63735a4e-6b31-11ec-b3df-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:6373832a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:6373ac7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.07']} DrugCentral uuid:6373d55a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:6373fe2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.4']} DrugCentral uuid:637426fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.27']} DrugCentral uuid:6374521e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:63747b0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:6374a3f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6E0 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 24) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.19']} DrugCentral uuid:6374ce56-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.68']} DrugCentral uuid:6374f9f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:637522f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:63754bd8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BZL6 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase D2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:63757522-6b31-11ec-b3df-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:63759eee-6b31-11ec-b3df-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:6375c7c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.13']} DrugCentral uuid:6375f09c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:637619d2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:637642b8-6b31-11ec-b3df-0242ac110002 UniProtKB:O96017 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Chk2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:63766b94-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:63769466-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:6376c116-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:6376ebb4-6b31-11ec-b3df-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.13']} DrugCentral uuid:6377149a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:63773dda-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:63776792-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2H9 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Microtubule-associated serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.26']} DrugCentral uuid:63779078-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.38']} DrugCentral uuid:6377b954-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:6377e294-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDR2 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 35) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.35']} DrugCentral uuid:63780b7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Receptor tyrosine-protein kinase erbB-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:63783460-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:63785d32-6b31-11ec-b3df-0242ac110002 UniProtKB:P51956 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase Nek3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:63788776-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.43']} DrugCentral uuid:6378b05c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.2']} DrugCentral uuid:6378d938-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:63790200-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY57 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib targets Kinase (Serine/threonine-protein kinase 32B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:63792b5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.62']} DrugCentral uuid:63795462-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.036']} DrugCentral uuid:63797d52-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5252 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 neratinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.229']} DrugCentral uuid:6379a70a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42345 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Serine/threonine-protein kinase mTOR) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.35']} DrugCentral uuid:6379d072-6b31-11ec-b3df-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.432']} DrugCentral uuid:6379f94e-6b31-11ec-b3df-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.194']} DrugCentral uuid:637a2248-6b31-11ec-b3df-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.155']} DrugCentral uuid:637a4ca0-6b31-11ec-b3df-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5256 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copanlisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.301']} DrugCentral uuid:637a78a6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95069 biolink:molecularly_interacts_with DrugCentral:5257 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 butylphthalide is blocker of Ion channel (Potassium channel subfamily K member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:637aa182-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.65']} DrugCentral uuid:637aca54-6b31-11ec-b3df-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.76']} DrugCentral uuid:637af39e-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.764']} DrugCentral uuid:637b1c70-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.788']} DrugCentral uuid:637b4678-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.375']} DrugCentral uuid:637b6f5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.866']} DrugCentral uuid:637b98a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.524']} DrugCentral uuid:637bc198-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.678']} DrugCentral uuid:637beaba-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.796']} DrugCentral uuid:637c13a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5258 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tivozanib is inhibitor of Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:637c3f6a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.96']} DrugCentral uuid:637c6850-6b31-11ec-b3df-0242ac110002 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:637c910e-6b31-11ec-b3df-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:637cba44-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:637ce316-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:637d0bde-6b31-11ec-b3df-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:637d34c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.62']} DrugCentral uuid:637d5e22-6b31-11ec-b3df-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5259 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abemaciclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.222']} DrugCentral uuid:637d880c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:637db0e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:637dd9ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:637e0462-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:637e2d2a-6b31-11ec-b3df-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.337']} DrugCentral uuid:637e55fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.032']} DrugCentral uuid:637e7eec-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.434']} DrugCentral uuid:637ea840-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5260 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 acalabrutinib is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.292']} DrugCentral uuid:637ed112-6b31-11ec-b3df-0242ac110002 UniProtKB:P37289 biolink:molecularly_interacts_with DrugCentral:5261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprostene bunod targets GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.01']} DrugCentral uuid:637efa0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43088 biolink:molecularly_interacts_with DrugCentral:5261 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 latanoprostene bunod is agonist of GPCR (Prostaglandin F2-alpha receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.6']} DrugCentral uuid:637f2b1c-6b31-11ec-b3df-0242ac110002 UniProtKB:F5HCU8 biolink:molecularly_interacts_with DrugCentral:5262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letermovir is inhibitor of Enzyme (DNA terminase complex) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:637f2b1c-6b31-11ec-b3df-0242ac110002 UniProtKB:F5HCU8 biolink:molecularly_interacts_with DrugCentral:5262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letermovir is inhibitor of Enzyme (DNA terminase complex) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:637f2b1c-6b31-11ec-b3df-0242ac110002 UniProtKB:F5HCU8 biolink:molecularly_interacts_with DrugCentral:5262 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 letermovir is inhibitor of Enzyme (DNA terminase complex) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.678']} DrugCentral uuid:637f6bf4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01344 biolink:molecularly_interacts_with DrugCentral:5263 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 benralizumab is antibody binding of Membrane receptor (Interleukin-5 receptor subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.959']} DrugCentral uuid:637f950c-6b31-11ec-b3df-0242ac110002 UniProtKB:P43220 biolink:molecularly_interacts_with DrugCentral:5267 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 semaglutide is agonist of GPCR (Glucagon-like peptide 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.42']} DrugCentral uuid:637fbe88-6b31-11ec-b3df-0242ac110002 UniProtKB:P00742 biolink:molecularly_interacts_with DrugCentral:5268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emicizumab is antibody binding of Enzyme (Coagulation factor X) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.73']} DrugCentral uuid:637fe8a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P00740 biolink:molecularly_interacts_with DrugCentral:5268 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emicizumab is antibody binding of Enzyme (Coagulation factor IX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:63801176-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:5269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 netarsudil is inhibitor of Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.49']} DrugCentral uuid:63803a70-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5269 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 netarsudil is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.377']} DrugCentral uuid:638063ba-6b31-11ec-b3df-0242ac110002 UniProtKB:P53792 biolink:molecularly_interacts_with DrugCentral:5270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertugliflozin targets Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.94']} DrugCentral uuid:63808ca0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NY91 biolink:molecularly_interacts_with DrugCentral:5270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertugliflozin targets Transporter (Low affinity sodium-glucose cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.06']} DrugCentral uuid:6380b572-6b31-11ec-b3df-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:5270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertugliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.708']} DrugCentral uuid:6380de62-6b31-11ec-b3df-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:5270 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ertugliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.057']} DrugCentral uuid:638107ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92847 biolink:molecularly_interacts_with DrugCentral:5271 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 macimorelin is agonist of GPCR (Growth hormone secretagogue receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:63813164-6b31-11ec-b3df-0242ac110002 UniProtKB:P50052 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II is agonist of GPCR (Type-2 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.2']} DrugCentral uuid:63815a9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29089 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II targets GPCR (Type-1B angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.51']} DrugCentral uuid:63818416-6b31-11ec-b3df-0242ac110002 UniProtKB:P25104 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II targets GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.24']} DrugCentral uuid:6381af72-6b31-11ec-b3df-0242ac110002 UniProtKB:P25095 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II targets GPCR (Type-1A angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:6381d9ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P30556 biolink:molecularly_interacts_with DrugCentral:5272 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 angiotensin II is agonist of GPCR (Type-1 angiotensin II receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:6382027e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bictegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:63822b5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bictegravir targets Unclassified (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:638254d6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:5274 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bictegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.125']} DrugCentral uuid:63827da8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:5275 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lutetium (177Lu) oxodotreotide is agonist of GPCR (Somatostatin receptor type 2) DrugCentral uuid:6382a292-6b31-11ec-b3df-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:5276 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tezacaftor is pharmacological chaperone of Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.57']} DrugCentral uuid:6382cb78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12908 biolink:molecularly_interacts_with DrugCentral:5277 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elobixibat is inhibitor of Transporter (Ileal sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.276']} DrugCentral uuid:6382f4e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:5278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apalutamide is antagonist of Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.03']} DrugCentral uuid:63831e0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:5278 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 apalutamide is inhibitor of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.796']} DrugCentral uuid:638346fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P01730 biolink:molecularly_interacts_with DrugCentral:5279 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibalizumab is antibody binding of Membrane receptor (T-cell surface glycoprotein CD4) DrugCentral uuid:63836b8c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:638395b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.16']} DrugCentral uuid:6383be8e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:6383e774-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DMS8 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib is inhibitor of GPCR (Adenosine receptor A3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.092']} DrugCentral uuid:638410d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5280 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostamatinib is inhibitor of Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.387']} DrugCentral uuid:63843d82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tildrakizumab is antibody binding of Cytokine (Interleukin-23) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.5']} DrugCentral uuid:63843d82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5281 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tildrakizumab is antibody binding of Cytokine (Interleukin-23) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.5']} DrugCentral uuid:63847284-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZV9 biolink:molecularly_interacts_with DrugCentral:5282 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 burosumab is antibody binding of Secreted (Fibroblast growth factor 23) DrugCentral uuid:63849732-6b31-11ec-b3df-0242ac110002 UniProtKB:P25103 biolink:molecularly_interacts_with DrugCentral:5283 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosnetupitant is antagonist of GPCR (Substance-P receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.022']} DrugCentral uuid:6384c4fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erenumab is antibody binding of GPCR (Calcitonin-gene-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.699']} DrugCentral uuid:6384c4fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5284 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erenumab is antibody binding of GPCR (Calcitonin-gene-related peptide receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.699']} DrugCentral uuid:6384fb0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P40238 biolink:molecularly_interacts_with DrugCentral:5285 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avatrombopag is agonist of Membrane receptor (Thrombopoietin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:638523e6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q25634 biolink:molecularly_interacts_with DrugCentral:5286 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxidectin is inhibitor of Ion channel (Glutamate-gated chloride channel) DrugCentral uuid:638549d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21554 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.62']} DrugCentral uuid:638573c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P34972 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.54']} DrugCentral uuid:63859cae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14330 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is agonist of GPCR (N-arachidonyl glycine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.29']} DrugCentral uuid:6385c580-6b31-11ec-b3df-0242ac110002 UniProtKB:P20272 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.9']} DrugCentral uuid:6385eed4-6b31-11ec-b3df-0242ac110002 UniProtKB:P47936 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets GPCR (Cannabinoid receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.64']} DrugCentral uuid:638617e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:638640aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WUD2 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.43']} DrugCentral uuid:638669b8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5S1 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is activator of Ion channel (Transient receptor potential cation channel subfamily V member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.5']} DrugCentral uuid:638692ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P97612 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol targets Enzyme (Fatty-acid amide hydrolase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.27']} DrugCentral uuid:6386bbd4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NER1 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is inhibitor of Ion channel (Transient receptor potential cation channel subfamily V member 1) DrugCentral uuid:6386e06e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2T6 biolink:molecularly_interacts_with DrugCentral:5288 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cannabidiol is antagonist of GPCR (G-protein coupled receptor 55) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:63870954-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16539 biolink:molecularly_interacts_with DrugCentral:5289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encorafenib targets Kinase (Mitogen-activated protein kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:6387335c-6b31-11ec-b3df-0242ac110002 UniProtKB:P04049 biolink:molecularly_interacts_with DrugCentral:5289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encorafenib is inhibitor of Kinase (RAF proto-oncogene serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.523']} DrugCentral uuid:63875c42-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5289 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 encorafenib is inhibitor of Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.328']} DrugCentral uuid:63878528-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 binimetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:6387ae22-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5290 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 binimetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.9']} DrugCentral uuid:6387d776-6b31-11ec-b3df-0242ac110002 UniProtKB:P33815 biolink:molecularly_interacts_with DrugCentral:5291 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tecovirimat is inhibitor of Viral envelope protein (Envelope protein F13) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.382']} DrugCentral uuid:63880066-6b31-11ec-b3df-0242ac110002 UniProtKB:O75874 biolink:molecularly_interacts_with DrugCentral:5292 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ivosidenib is inhibitor of Enzyme (Isocitrate dehydrogenase [NADP] cytoplasmic) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.149']} DrugCentral uuid:63882942-6b31-11ec-b3df-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:5293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elagolix targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.36']} DrugCentral uuid:63885282-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8SPZ1 biolink:molecularly_interacts_with DrugCentral:5293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elagolix targets GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.48']} DrugCentral uuid:63887cd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:5293 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elagolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.824']} DrugCentral uuid:6388a5ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:5295 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doravirine targets Enzyme (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:6388ce9c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9WKE8 biolink:molecularly_interacts_with DrugCentral:5295 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doravirine targets Unclassified (Reverse transcriptase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:6388fa16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q72547 biolink:molecularly_interacts_with DrugCentral:5295 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 doravirine is inhibitor of Enzyme (Reverse transcriptase/RNaseH) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.921']} DrugCentral uuid:63892446-6b31-11ec-b3df-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.8']} DrugCentral uuid:63894d0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:6389768a-6b31-11ec-b3df-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.638']} DrugCentral uuid:6389a006-6b31-11ec-b3df-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5296 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 duvelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.62']} DrugCentral uuid:6389c8ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.45']} DrugCentral uuid:6389f1dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:638a1aa4-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:638a43f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:638a6cf2-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.34']} DrugCentral uuid:638a95e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5297 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dacomitinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.133']} DrugCentral uuid:638abed2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talazoparib tosylate is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.06']} DrugCentral uuid:638ae93e-6b31-11ec-b3df-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5300 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 talazoparib tosylate is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.921']} DrugCentral uuid:638b1256-6b31-11ec-b3df-0242ac110002 UniProtKB:P03433 biolink:molecularly_interacts_with DrugCentral:5301 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 baloxavir marboxil is inhibitor of Enzyme (Polymerase acidic protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.854']} DrugCentral uuid:638b3b3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.28']} DrugCentral uuid:638b64ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.959']} DrugCentral uuid:638b8dee-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.301']} DrugCentral uuid:638bb6ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:638bdfba-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.62']} DrugCentral uuid:638c08fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.481']} DrugCentral uuid:638c31ea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.77']} DrugCentral uuid:638c5ad0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.638']} DrugCentral uuid:638c83ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.854']} DrugCentral uuid:638cae40-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.337']} DrugCentral uuid:638cd82a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.569']} DrugCentral uuid:638d0110-6b31-11ec-b3df-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:5302 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lorlatinib is inhibitor of Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.222']} DrugCentral uuid:638d2a0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11229 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.38']} DrugCentral uuid:638d5426-6b31-11ec-b3df-0242ac110002 UniProtKB:P08172 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.52']} DrugCentral uuid:638d7d3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.75']} DrugCentral uuid:638da642-6b31-11ec-b3df-0242ac110002 UniProtKB:P08173 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:638dd04a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08912 biolink:molecularly_interacts_with DrugCentral:5303 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 revefenacin is antagonist of GPCR (Muscarinic acetylcholine receptor M5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.2']} DrugCentral uuid:638df93a-6b31-11ec-b3df-0242ac110002 UniProtKB:P56726 biolink:molecularly_interacts_with DrugCentral:5304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glasdegib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:638e2216-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5304 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 glasdegib is antagonist of GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:638e4afc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 larotrectinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.187']} DrugCentral uuid:638e7536-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 larotrectinib is inhibitor of Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.092']} DrugCentral uuid:638e9e30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5305 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 larotrectinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.975']} DrugCentral uuid:638ec78e-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:638ef074-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.96']} DrugCentral uuid:638f1a72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.82']} DrugCentral uuid:638f44ac-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.1']} DrugCentral uuid:638f6d7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.7']} DrugCentral uuid:638f9664-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:638fc062-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:638fe95c-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5306 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gilteritinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.301']} DrugCentral uuid:63901242-6b31-11ec-b3df-0242ac110002 UniProtKB:P41180 biolink:molecularly_interacts_with DrugCentral:5307 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evocalcet is agonist of GPCR (Extracellular calcium-sensing receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.032']} DrugCentral uuid:63903b14-6b31-11ec-b3df-0242ac110002 UniProtKB:P04275 biolink:molecularly_interacts_with DrugCentral:5308 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 caplacizumab is antibody binding of Unclassified (von Willebrand factor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.509']} DrugCentral uuid:639066a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:5309 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lanadelumab is antibody binding of Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.05']} DrugCentral uuid:63908f7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P26255 biolink:molecularly_interacts_with DrugCentral:5311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vibegron targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.07']} DrugCentral uuid:6390b9d6-6b31-11ec-b3df-0242ac110002 UniProtKB:O02662 biolink:molecularly_interacts_with DrugCentral:5311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vibegron targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:6390e348-6b31-11ec-b3df-0242ac110002 UniProtKB:Q28524 biolink:molecularly_interacts_with DrugCentral:5311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vibegron targets GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.24']} DrugCentral uuid:63910c2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P13945 biolink:molecularly_interacts_with DrugCentral:5311 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vibegron is agonist of GPCR (Beta-3 adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.959']} DrugCentral uuid:63913596-6b31-11ec-b3df-0242ac110002 UniProtKB:P43116 biolink:molecularly_interacts_with DrugCentral:5312 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 omidenepag isopropyl is agonist of GPCR (Prostaglandin E2 receptor EP2 subtype) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.081']} DrugCentral uuid:63915e5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:5313 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 patisiran is antisense inhibitor of RNA (transthyretin (TTR) mRNA) DrugCentral uuid:6391835c-6b31-11ec-b3df-0242ac110002 UniProtKB:P20273 biolink:molecularly_interacts_with DrugCentral:5314 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 moxetumomab pasudotox is binding agent of Membrane receptor (B-cell receptor CD22) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.2']} DrugCentral uuid:6391ac42-6b31-11ec-b3df-0242ac110002 UniProtKB:P06881 biolink:molecularly_interacts_with DrugCentral:5315 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fremanezumab is antibody binding of GPCR (Calcitonin gene-related peptide 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.3']} DrugCentral uuid:6391d528-6b31-11ec-b3df-0242ac110002 UniProtKB:P06881 biolink:molecularly_interacts_with DrugCentral:5316 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 galcanezumab is antibody binding of GPCR (Calcitonin gene-related peptide 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.7']} DrugCentral uuid:6391fe22-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:5317 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cemiplimab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.102']} DrugCentral uuid:63922898-6b31-11ec-b3df-0242ac110002 UniProtKB:P02766 biolink:molecularly_interacts_with DrugCentral:5319 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inotersen is antisense inhibitor of RNA (transthyretin (TTR) mRNA) DrugCentral uuid:63924d46-6b31-11ec-b3df-0242ac110002 UniProtKB:P01579 biolink:molecularly_interacts_with DrugCentral:5320 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 emapalumab is antibody binding of Cytokine (Interferon gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.1']} DrugCentral uuid:6392764a-6b31-11ec-b3df-0242ac110002 UniProtKB:P01031 biolink:molecularly_interacts_with DrugCentral:5322 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ravulizumab is antibody binding of Secreted (Complement C5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.357']} DrugCentral uuid:6392a322-6b31-11ec-b3df-0242ac110002 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tagraxofusp is binding agent of Membrane receptor (Interleukin-3 receptor) DrugCentral uuid:6392a322-6b31-11ec-b3df-0242ac110002 UniProtKB:P32927 biolink:molecularly_interacts_with DrugCentral:5323 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tagraxofusp is binding agent of Membrane receptor (Interleukin-3 receptor) DrugCentral uuid:6392d2f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P11413 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone targets Enzyme (Glucose-6-phosphate 1-dehydrogenase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.18']} DrugCentral uuid:6393038a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:6393038a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:6393038a-6b31-11ec-b3df-0242ac110002 UniProtKB:P47870 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.222']} DrugCentral uuid:63934be2-6b31-11ec-b3df-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:63934be2-6b31-11ec-b3df-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:63934be2-6b31-11ec-b3df-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA A receptor alpha-4/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.097']} DrugCentral uuid:639394a8-6b31-11ec-b3df-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:639394a8-6b31-11ec-b3df-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:639394a8-6b31-11ec-b3df-0242ac110002 UniProtKB:O14764 biolink:molecularly_interacts_with DrugCentral:5324 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brexanolone is positive allosteric modulator of Ion channel (GABA-A receptor alpha-6/beta-3/delta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.81']} DrugCentral uuid:6393d562-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:5325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solriamfetol is inhibitor of Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.088']} DrugCentral uuid:6394017c-6b31-11ec-b3df-0242ac110002 UniProtKB:P23975 biolink:molecularly_interacts_with DrugCentral:5325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solriamfetol is inhibitor of Transporter (Sodium-dependent noradrenaline transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.432']} DrugCentral uuid:63942b7a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01959 biolink:molecularly_interacts_with DrugCentral:5325 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 solriamfetol is inhibitor of Transporter (Sodium-dependent dopamine transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['4.848']} DrugCentral uuid:6394546a-6b31-11ec-b3df-0242ac110002 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.125']} DrugCentral uuid:63947d78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['3']} DrugCentral uuid:6394a726-6b31-11ec-b3df-0242ac110002 UniProtKB:O95136 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4']} DrugCentral uuid:6394d002-6b31-11ec-b3df-0242ac110002 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.409']} DrugCentral uuid:6394f8de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:5326 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 siponimod is modulator of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.009']} DrugCentral uuid:6395219c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:63954ad2-6b31-11ec-b3df-0242ac110002 UniProtKB:P35918 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10']} DrugCentral uuid:639574ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.434']} DrugCentral uuid:63959dde-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.523']} DrugCentral uuid:6395c7dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.921']} DrugCentral uuid:6395f0e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.602']} DrugCentral uuid:63961aca-6b31-11ec-b3df-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5327 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 erdafitinib is inhibitor of Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.244']} DrugCentral uuid:639643b0-6b31-11ec-b3df-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.54']} DrugCentral uuid:63966d40-6b31-11ec-b3df-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.92']} DrugCentral uuid:6396961c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:6396bf0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Z1L0 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:6396e81a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5328 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 alpelisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.337']} DrugCentral uuid:63971178-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.77']} DrugCentral uuid:63973a9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.62']} DrugCentral uuid:63976376-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['10.02']} DrugCentral uuid:63978c48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01718 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Adrenocorticotropic hormone receptor) DrugCentral uuid:6397b402-6b31-11ec-b3df-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:5329 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bremelanotide is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8']} DrugCentral uuid:6397e120-6b31-11ec-b3df-0242ac110002 UniProtKB:O14980 biolink:molecularly_interacts_with DrugCentral:5330 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selinexor is inhibitor of Nuclear other (Exportin-1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.7']} DrugCentral uuid:63980c68-6b31-11ec-b3df-0242ac110002 UniProtKB:P60880 biolink:molecularly_interacts_with DrugCentral:5331 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 prabotulinumtoxinA is blocker of Cytosolic other (Synaptosomal-associated protein 25) DrugCentral uuid:639850a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:639850a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:639850a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:639850a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:639850a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:639850a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:639850a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:639850a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:639850a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:6398c806-6b31-11ec-b3df-0242ac110002 UniProtKB:P40259 biolink:molecularly_interacts_with DrugCentral:5333 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 polatuzumab vedotin is antibody binding of Tumour-associated antigen (B-cell antigen receptor complex-associated protein beta chain) DrugCentral uuid:6398ed04-6b31-11ec-b3df-0242ac110002 UniProtKB:P15207 biolink:molecularly_interacts_with DrugCentral:5334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darolutamide is antagonist of Transcription factor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.96']} DrugCentral uuid:63991612-6b31-11ec-b3df-0242ac110002 UniProtKB:P06401 biolink:molecularly_interacts_with DrugCentral:5334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darolutamide is antagonist of Nuclear hormone receptor (Progesterone receptor) DrugCentral uuid:63993ac0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:5334 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 darolutamide is inhibitor of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.187']} DrugCentral uuid:639963a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P02656 biolink:molecularly_interacts_with DrugCentral:5335 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 volanesorsen is antisense inhibitor of RNA (apolipoprotein C-III (apoC-III) mRNA) DrugCentral uuid:63998a98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NPF7 biolink:molecularly_interacts_with DrugCentral:5337 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 risankizumab is inhibitor of Cytokine (Interleukin-23 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11']} DrugCentral uuid:6399b7a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropeginterferon alfa-2b is binding agent of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:6399b7a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P48551 biolink:molecularly_interacts_with DrugCentral:5338 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ropeginterferon alfa-2b is binding agent of Membrane receptor (Interferon alpha/beta receptor) DrugCentral uuid:6399e6c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P31639 biolink:molecularly_interacts_with DrugCentral:5339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.745']} DrugCentral uuid:639a1062-6b31-11ec-b3df-0242ac110002 UniProtKB:P13866 biolink:molecularly_interacts_with DrugCentral:5339 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotagliflozin is inhibitor of Transporter (Sodium/glucose cotransporter 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.444']} DrugCentral uuid:639a39d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:639a62a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:639a8b82-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:639ab4b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:639add94-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:639b0670-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:639b3096-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.06']} DrugCentral uuid:639b5d82-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.39']} DrugCentral uuid:639b8668-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:639baf4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:639bd866-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:639c01ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:639c2af0-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:639c53d6-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:639c7d2a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.04']} DrugCentral uuid:639ca610-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKE5 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (TRAF2 and NCK-interacting protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:639ccf0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:639cf7dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:639d228e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y4K4 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.36']} DrugCentral uuid:639d4bb0-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:639d7496-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.43']} DrugCentral uuid:639d9d7c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.34']} DrugCentral uuid:639dc720-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:639df006-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:639e18e2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:639e41c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:639e6af4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.26']} DrugCentral uuid:639e93ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:639ebcd4-6b31-11ec-b3df-0242ac110002 UniProtKB:O95819 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:639ee5a6-6b31-11ec-b3df-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:639f0f72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:639f3862-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.05']} DrugCentral uuid:639f624c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:639f8bdc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.5']} DrugCentral uuid:639fb4c2-6b31-11ec-b3df-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:639fdda8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:63a006f2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:63a03050-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5341 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 quizartinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.796']} DrugCentral uuid:63a05936-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8RL90 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam targets Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:63a08226-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2PUH3 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.4']} DrugCentral uuid:63a0ab02-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9X5A7 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.33']} DrugCentral uuid:63a0d5aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q93LQ9 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.64']} DrugCentral uuid:63a0fe9a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q93DC4 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.59']} DrugCentral uuid:63a12794-6b31-11ec-b3df-0242ac110002 UniProtKB:B1PL86 biolink:molecularly_interacts_with DrugCentral:5342 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relebactam is inhibitor of Enzyme (Beta-lactamase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:63a15070-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:63a17a00-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.06']} DrugCentral uuid:63a1a2c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.36']} DrugCentral uuid:63a1cbae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.05']} DrugCentral uuid:63a1f4da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BWU1 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Cyclin-dependent kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:63a21ee2-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.56']} DrugCentral uuid:63a247be-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:63a270ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5343 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pexidartinib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.88']} DrugCentral uuid:63a29ade-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.46']} DrugCentral uuid:63a2c432-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.79']} DrugCentral uuid:63a2ed04-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:63a315e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:63a33f70-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:63a36964-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.85']} DrugCentral uuid:63a3924a-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.95']} DrugCentral uuid:63a3bb26-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.67']} DrugCentral uuid:63a3e45c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.71']} DrugCentral uuid:63a40d92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:63a43682-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:63a45f72-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:63a48c0e-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:63a4b846-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.92']} DrugCentral uuid:63a4e12c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:63a50a80-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.3']} DrugCentral uuid:63a5337a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5345 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 entrectinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.15']} DrugCentral uuid:63a55c60-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 upadacitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:63a58550-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 upadacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.63']} DrugCentral uuid:63a5aeb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 upadacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.33']} DrugCentral uuid:63a5d816-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5346 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 upadacitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.92']} DrugCentral uuid:63a600f2-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:63a62a0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.4']} DrugCentral uuid:63a65610-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.34']} DrugCentral uuid:63a68252-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:63a6ae30-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.12']} DrugCentral uuid:63a6d770-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.14']} DrugCentral uuid:63a7004c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:63a72932-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.42']} DrugCentral uuid:63a75222-6b31-11ec-b3df-0242ac110002 UniProtKB:P29317 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:63a77c52-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.03']} DrugCentral uuid:63a7a538-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:63a7ce0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:63a7f6e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:63a821d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:63a84da8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:63a876d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:63a89fb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P51812 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.09']} DrugCentral uuid:63a8c8fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P15735 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, liver/testis isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:63a8f320-6b31-11ec-b3df-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:63a91c1a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15746 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myosin light chain kinase, smooth muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:63a94500-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:63a96e9a-6b31-11ec-b3df-0242ac110002 UniProtKB:O43293 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Death-associated protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.92']} DrugCentral uuid:63a99780-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14012 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:63a9c08e-6b31-11ec-b3df-0242ac110002 UniProtKB:P45983 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.58']} DrugCentral uuid:63a9ead2-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:63aa1408-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13464 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Rho-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:63aa3cee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q05397 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Focal adhesion kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.38']} DrugCentral uuid:63aa65e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P08631 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase HCK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:63aa8f32-6b31-11ec-b3df-0242ac110002 UniProtKB:P53350 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:63aab80e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:63aae0fe-6b31-11ec-b3df-0242ac110002 UniProtKB:P53779 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:63ab09da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UIK4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Death-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.54']} DrugCentral uuid:63ab336a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:63ab5c50-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:63ab8630-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:63abaf16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13557 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit delta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:63abdb1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H1R3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myosin light chain kinase 2, skeletal/cardiac muscle) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.52']} DrugCentral uuid:63ac0484-6b31-11ec-b3df-0242ac110002 UniProtKB:P41240 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase CSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.23']} DrugCentral uuid:63ac2d88-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:63ac56e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P29322 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.11']} DrugCentral uuid:63ac7fd6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13555 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.27']} DrugCentral uuid:63aca952-6b31-11ec-b3df-0242ac110002 UniProtKB:Q2M2I8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (AP2-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.46']} DrugCentral uuid:63acd24c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7KZI7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase MARK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:63acfb96-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:63ad24a4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.3']} DrugCentral uuid:63ad4d9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:63ad7670-6b31-11ec-b3df-0242ac110002 UniProtKB:P51955 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:63ada06e-6b31-11ec-b3df-0242ac110002 UniProtKB:P53667 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (LIM domain kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.03']} DrugCentral uuid:63adc954-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15349 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:63adf23a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:63ae1b16-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13554 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:63ae449c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.55']} DrugCentral uuid:63ae6d82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16816 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.48']} DrugCentral uuid:63ae9654-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQM7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:63aebf3a-6b31-11ec-b3df-0242ac110002 UniProtKB:O94768 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 17B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.35']} DrugCentral uuid:63aee8a2-6b31-11ec-b3df-0242ac110002 UniProtKB:O94804 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:63af117e-6b31-11ec-b3df-0242ac110002 UniProtKB:P16591 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:63af3ac8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02156 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Protein kinase C epsilon type) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.09']} DrugCentral uuid:63af649e-6b31-11ec-b3df-0242ac110002 UniProtKB:O00444 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.02']} DrugCentral uuid:63af8f5a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UQB9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Aurora kinase C) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:63afb836-6b31-11ec-b3df-0242ac110002 UniProtKB:O75716 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.18']} DrugCentral uuid:63afe22a-6b31-11ec-b3df-0242ac110002 UniProtKB:P33981 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase TTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.35']} DrugCentral uuid:63b00bba-6b31-11ec-b3df-0242ac110002 UniProtKB:P42684 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Abelson tyrosine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:63b034a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P54764 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:63b05d90-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.33']} DrugCentral uuid:63b08694-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16512 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase N1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:63b0afe8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEE5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 17A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:63b0d8d8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UF33 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:63b101a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P09769 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fgr) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.09']} DrugCentral uuid:63b12a7c-6b31-11ec-b3df-0242ac110002 UniProtKB:O14965 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Aurora kinase A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:63b153f8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:63b17cde-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRP7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 36) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:63b1a5b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P29320 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.15']} DrugCentral uuid:63b1ce8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NSY1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (BMP-2-inducible protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.5']} DrugCentral uuid:63b1f826-6b31-11ec-b3df-0242ac110002 UniProtKB:P42685 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase FRK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.7']} DrugCentral uuid:63b22102-6b31-11ec-b3df-0242ac110002 UniProtKB:P49759 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase CLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:63b249de-6b31-11ec-b3df-0242ac110002 UniProtKB:P49760 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase CLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.64']} DrugCentral uuid:63b27332-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y6R4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:63b29c2c-6b31-11ec-b3df-0242ac110002 UniProtKB:O14976 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-G-associated kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.96']} DrugCentral uuid:63b2c526-6b31-11ec-b3df-0242ac110002 UniProtKB:O43353 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.21']} DrugCentral uuid:63b2ee0c-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:63b31882-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IU85 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1D) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.34']} DrugCentral uuid:63b34474-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00536 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 16) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:63b36eb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07912 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Activated CDC42 kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.19']} DrugCentral uuid:63b398a2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15375 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.19']} DrugCentral uuid:63b3c2be-6b31-11ec-b3df-0242ac110002 UniProtKB:O75582 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:63b3ebb8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2G2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (STE20-like serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.17']} DrugCentral uuid:63b414bc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HAZ1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity protein kinase CLK4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:63b43d98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HBH9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.42']} DrugCentral uuid:63b469da-6b31-11ec-b3df-0242ac110002 UniProtKB:P45984 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.62']} DrugCentral uuid:63b492d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96RR4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.4']} DrugCentral uuid:63b4bbb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P27448 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (MAP/microtubule affinity-regulating kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:63b4e5a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N5S9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:63b50ee4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NX5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium/calmodulin-dependent protein kinase type 1G) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:63b537c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:63b560c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P54760 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:63b58a2c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BXA7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Testis-specific serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:63b5b312-6b31-11ec-b3df-0242ac110002 UniProtKB:P36896 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Activin receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.17']} DrugCentral uuid:63b5dbf8-6b31-11ec-b3df-0242ac110002 UniProtKB:P37023 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase receptor R3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:63b604de-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04771 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Activin receptor type-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:63b62e28-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96Q40 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:63b65704-6b31-11ec-b3df-0242ac110002 UniProtKB:O14920 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:63b67ff4-6b31-11ec-b3df-0242ac110002 UniProtKB:P37173 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (TGF-beta receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:63b6aa06-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.29']} DrugCentral uuid:63b6d4cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:63b6fd94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08881 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase ITK/TSK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:63b7267a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43403 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase ZAP-70) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:63b74f60-6b31-11ec-b3df-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.06']} DrugCentral uuid:63b778aa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13882 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Protein-tyrosine kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:63b7a276-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:63b7cb84-6b31-11ec-b3df-0242ac110002 UniProtKB:P30530 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase receptor UFO) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:63b7f4c4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:63b81d96-6b31-11ec-b3df-0242ac110002 UniProtKB:P29323 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:63b84686-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:63b86f76-6b31-11ec-b3df-0242ac110002 UniProtKB:P23443 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:63b89a78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9C098 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase DCLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.89']} DrugCentral uuid:63b8c4b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UK32 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:63b8ed98-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.31']} DrugCentral uuid:63b91674-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13470 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Non-receptor tyrosine-protein kinase TNK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:63b93fc8-6b31-11ec-b3df-0242ac110002 UniProtKB:O14757 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Chk1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:63b968ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.41']} DrugCentral uuid:63b991a8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00537 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.46']} DrugCentral uuid:63b9baa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07002 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 18) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.57']} DrugCentral uuid:63b9e45a-6b31-11ec-b3df-0242ac110002 UniProtKB:O94921 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 14) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:63ba0d4a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99755 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:63ba3630-6b31-11ec-b3df-0242ac110002 UniProtKB:P78356 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:63ba6074-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86YV6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myosin light chain kinase family member 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.89']} DrugCentral uuid:63ba8a2c-6b31-11ec-b3df-0242ac110002 UniProtKB:P30291 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Wee1-like protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:63bab326-6b31-11ec-b3df-0242ac110002 UniProtKB:O00506 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 25) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:63badc34-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYL2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase MLT) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:63bb0560-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14289 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Protein-tyrosine kinase 2-beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:63bb2e3c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BRS2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase RIO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:63bb5704-6b31-11ec-b3df-0242ac110002 UniProtKB:P35590 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase receptor Tie-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:63bb7fea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UKI8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase tousled-like 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:63bbaa92-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86UE8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase tousled-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:63bbd364-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.07']} DrugCentral uuid:63bbfc54-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.82']} DrugCentral uuid:63bc2530-6b31-11ec-b3df-0242ac110002 UniProtKB:P68400 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Casein kinase II subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.04']} DrugCentral uuid:63bc4f56-6b31-11ec-b3df-0242ac110002 UniProtKB:P19784 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Casein kinase II subunit alpha') {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:63bc7846-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y463 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity tyrosine-phosphorylation-regulated kinase 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:63bca12c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14164 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:63bcca08-6b31-11ec-b3df-0242ac110002 UniProtKB:P53671 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (LIM domain kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:63bcf370-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15831 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase STK11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.51']} DrugCentral uuid:63bd1c56-6b31-11ec-b3df-0242ac110002 UniProtKB:P46734 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.46']} DrugCentral uuid:63bd453c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14680 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Maternal embryonic leucine zipper kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:63bd6e90-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BUB5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (MAP kinase-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:63bd98ca-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P289 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 26) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:63bdc1ba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TDX7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:63bdeaa0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P2K8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:63be1570-6b31-11ec-b3df-0242ac110002 UniProtKB:P14616 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Insulin receptor-related protein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:63be40fe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y616 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Interleukin-1 receptor-associated kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:63be6a0c-6b31-11ec-b3df-0242ac110002 UniProtKB:O14730 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase RIO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:63be9356-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H0K1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SIK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.01']} DrugCentral uuid:63bebc96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96SB4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (SRSF protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.8']} DrugCentral uuid:63bee586-6b31-11ec-b3df-0242ac110002 UniProtKB:P78362 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (SRSF protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:63bf0e62-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BYT3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 33) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:63bf3734-6b31-11ec-b3df-0242ac110002 UniProtKB:Q59H18 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TNNI3K) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:63bf606a-6b31-11ec-b3df-0242ac110002 UniProtKB:P54646 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.33']} DrugCentral uuid:63bf8946-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NFD2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ankyrin repeat and protein kinase domain-containing protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.37']} DrugCentral uuid:63bfb308-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16832 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Discoidin domain-containing receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.02']} DrugCentral uuid:63bfdcc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q09013 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myotonin-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:63c00650-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NI60 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Chaperone activity of bc1 complex-like, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:63c02f36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRM7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase LATS2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.1']} DrugCentral uuid:63c05830-6b31-11ec-b3df-0242ac110002 UniProtKB:P29376 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Leukocyte tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:63c0817a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92918 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:63c0aa74-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NQU5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:63c0d33c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P286 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:63c0fc18-6b31-11ec-b3df-0242ac110002 UniProtKB:O60285 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (NUAK family SNF1-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.47']} DrugCentral uuid:63c12562-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IVH8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.75']} DrugCentral uuid:63c14ed4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.31']} DrugCentral uuid:63c177a6-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:63c1a078-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13873 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Bone morphogenetic protein receptor type-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:63c1cb70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9P0L2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase MARK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.16']} DrugCentral uuid:63c1f44c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96L34 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (MAP/microtubule affinity-regulating kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.01']} DrugCentral uuid:63c21d3c-6b31-11ec-b3df-0242ac110002 UniProtKB:P45985 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:63c2462c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12866 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Mer) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.09']} DrugCentral uuid:63c26f76-6b31-11ec-b3df-0242ac110002 UniProtKB:P80192 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:63c2985c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02779 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.16']} DrugCentral uuid:63c2c142-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16584 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:63c2ea96-6b31-11ec-b3df-0242ac110002 UniProtKB:O15146 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Muscle, skeletal receptor tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:63c31372-6b31-11ec-b3df-0242ac110002 UniProtKB:O14578 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Citron Rho-interacting kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:63c33c4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P53355 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Death-associated protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.8']} DrugCentral uuid:63c3653e-6b31-11ec-b3df-0242ac110002 UniProtKB:O15075 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase DCLK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.72']} DrugCentral uuid:63c38fc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N568 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase DCLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:63c3bcaa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6P3R8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:63c3e874-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TD19 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek9) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.82']} DrugCentral uuid:63c4115a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13153 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:63c43aa4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13177 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:63c464c0-6b31-11ec-b3df-0242ac110002 UniProtKB:O96013 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PAK 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:63c48dba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96D53 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (AarF domain-containing protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:63c4b6b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P57059 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SIK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.41']} DrugCentral uuid:63c4dffe-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H3Y6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Srms) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.3']} DrugCentral uuid:63c508da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15569 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity testis-specific protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.5']} DrugCentral uuid:63c531d4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21709 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-A receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.14']} DrugCentral uuid:63c55bb4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H4B4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:63c58800-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16659 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:63c5b0be-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13164 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.18']} DrugCentral uuid:63c5d99a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TD08 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase 15) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.29']} DrugCentral uuid:63c602e4-6b31-11ec-b3df-0242ac110002 UniProtKB:O94806 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase D3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.02']} DrugCentral uuid:63c62bc0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13237 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (cGMP-dependent protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:63c65492-6b31-11ec-b3df-0242ac110002 UniProtKB:P19525 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Interferon-induced, double-stranded RNA-activated protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.96']} DrugCentral uuid:63c67d6e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13546 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.28']} DrugCentral uuid:63c6a6b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P07332 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Tyrosine-protein kinase Fes/Fps) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.28']} DrugCentral uuid:63c6cfa8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.7']} DrugCentral uuid:63c6f88e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.22']} DrugCentral uuid:63c7217e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15418 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.38']} DrugCentral uuid:63c74db6-6b31-11ec-b3df-0242ac110002 UniProtKB:O75676 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ribosomal protein S6 kinase alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.85']} DrugCentral uuid:63c7769c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.12']} DrugCentral uuid:63c79f8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12851 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.68']} DrugCentral uuid:63c7c962-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N4C8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Misshapen-like kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.05']} DrugCentral uuid:63c7f2b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UHD2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.04']} DrugCentral uuid:63c81c14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:63c844dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:63c86e30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92772 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase-like 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:63c89702-6b31-11ec-b3df-0242ac110002 UniProtKB:O15197 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Ephrin type-B receptor 6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.52']} DrugCentral uuid:63c8c006-6b31-11ec-b3df-0242ac110002 UniProtKB:O75460 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase/endoribonuclease IRE1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:63c8e8f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P32298 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (G protein-coupled receptor kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:63c9136c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8WTQ7 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (G protein-coupled receptor kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:63c93c52-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2X6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:63c96542-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H422 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:63c98e1e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NE63 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:63c9b786-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPZ9 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ICK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:63c9e06c-6b31-11ec-b3df-0242ac110002 UniProtKB:O15111 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Inhibitor of nuclear factor kappa-B kinase subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.08']} DrugCentral uuid:63ca0966-6b31-11ec-b3df-0242ac110002 UniProtKB:P51617 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Interleukin-1 receptor-associated kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.66']} DrugCentral uuid:63ca324c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43283 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 13) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.23']} DrugCentral uuid:63ca5b82-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2U5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.24']} DrugCentral uuid:63ca8486-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99759 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:63caad58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15208 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase 38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.24']} DrugCentral uuid:63cad63e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IY84 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase NIM1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.36']} DrugCentral uuid:63cb0078-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BVS4 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase RIO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.58']} DrugCentral uuid:63cb294a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UPE1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (SRSF protein kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.77']} DrugCentral uuid:63cb5366-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UEW8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (STE20/SPS1-related proline-alanine-rich protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:63cb7c9c-6b31-11ec-b3df-0242ac110002 UniProtKB:O43318 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.51']} DrugCentral uuid:63cba578-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7L7X3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TAO1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.89']} DrugCentral uuid:63cbcf58-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H2K8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TAO3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:63cbf834-6b31-11ec-b3df-0242ac110002 UniProtKB:O75385 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ULK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.57']} DrugCentral uuid:63cc21b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8IYT8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ULK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.1']} DrugCentral uuid:63cc4a96-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6PHR2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase ULK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.54']} DrugCentral uuid:63cc7386-6b31-11ec-b3df-0242ac110002 UniProtKB:Q56UN5 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.72']} DrugCentral uuid:63cc9c62-6b31-11ec-b3df-0242ac110002 UniProtKB:Q86Z02 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Homeodomain-interacting protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.07']} DrugCentral uuid:63ccc6ce-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NYY3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PLK2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.62']} DrugCentral uuid:63ccefc8-6b31-11ec-b3df-0242ac110002 UniProtKB:P57078 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Receptor-interacting serine/threonine-protein kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:63cd18ae-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C264 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Uncharacterized serine/threonine-protein kinase SBK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.54']} DrugCentral uuid:63cd4180-6b31-11ec-b3df-0242ac110002 UniProtKB:O76039 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Cyclin-dependent kinase-like 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.14']} DrugCentral uuid:63cd6aca-6b31-11ec-b3df-0242ac110002 UniProtKB:P42679 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Megakaryocyte-associated tyrosine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:63cd93a6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UBF8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 4-kinase beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:63cdbcc8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y2K2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SIK3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.72']} DrugCentral uuid:63cde626-6b31-11ec-b3df-0242ac110002 UniProtKB:P0C1S8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Wee1-like protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.22']} DrugCentral uuid:63ce0f34-6b31-11ec-b3df-0242ac110002 UniProtKB:O00238 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Bone morphogenetic protein receptor type-1B) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.39']} DrugCentral uuid:63ce381a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q52WX2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase SBK1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.1']} DrugCentral uuid:63ce60f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P51956 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.19']} DrugCentral uuid:63ce8b44-6b31-11ec-b3df-0242ac110002 UniProtKB:O14936 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Peripheral plasma membrane protein CASK) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.55']} DrugCentral uuid:63ceb75e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13523 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PRP4 homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.41']} DrugCentral uuid:63cee332-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12852 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Mitogen-activated protein kinase kinase kinase 12) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.2']} DrugCentral uuid:63cf0c36-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96BR1 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Sgk3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.6']} DrugCentral uuid:63cf35da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BQI3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Eukaryotic translation initiation factor 2-alpha kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6']} DrugCentral uuid:63cf5eb6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UL54 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase TAO2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.12']} DrugCentral uuid:63cf87b0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NRH2 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (SNF-related serine/threonine-protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.64']} DrugCentral uuid:63cfb0a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TBX8 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.39']} DrugCentral uuid:63cfdaee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13163 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual specificity mitogen-activated protein kinase kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.44']} DrugCentral uuid:63d003d4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8NG66 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:63d02cba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q32MK0 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Myosin light chain kinase 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.01']} DrugCentral uuid:63d055a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q5S007 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Leucine-rich repeat serine/threonine-protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.06']} DrugCentral uuid:63d0802a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6XUX3 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Dual serine/threonine and tyrosine protein kinase) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.77']} DrugCentral uuid:63d0a8fc-6b31-11ec-b3df-0242ac110002 UniProtKB:P62344 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Calcium-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.92']} DrugCentral uuid:63d0d1f6-6b31-11ec-b3df-0242ac110002 UniProtKB:O60885 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Unclassified (Bromodomain-containing protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.79']} DrugCentral uuid:63d0fb90-6b31-11ec-b3df-0242ac110002 UniProtKB:P9WI81 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase PknB) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7']} DrugCentral uuid:63d1246c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9HC98 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek6) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.92']} DrugCentral uuid:63d14d48-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13976 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (cGMP-dependent protein kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.42']} DrugCentral uuid:63d1762e-6b31-11ec-b3df-0242ac110002 UniProtKB:P51957 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.8']} DrugCentral uuid:63d19fa0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q58F21 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Unclassified (Bromodomain testis-specific protein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:63d1c87c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96PY6 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib targets Kinase (Serine/threonine-protein kinase Nek1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.47']} DrugCentral uuid:63d1f176-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.99']} DrugCentral uuid:63d21b7e-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.97']} DrugCentral uuid:63d246da-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:63d26fc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.82']} DrugCentral uuid:63d298c4-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5347 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fedratinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:63d2c1aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P26433 biolink:molecularly_interacts_with DrugCentral:5349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenapanor targets Transporter (Sodium/hydrogen exchanger 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.2']} DrugCentral uuid:63d2eb6c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48764 biolink:molecularly_interacts_with DrugCentral:5349 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tenapanor is inhibitor of Transporter (Sodium/hydrogen exchanger 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.06']} DrugCentral uuid:63d31470-6b31-11ec-b3df-0242ac110002 UniProtKB:P10276 biolink:molecularly_interacts_with DrugCentral:5350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:63d33d56-6b31-11ec-b3df-0242ac110002 UniProtKB:P10826 biolink:molecularly_interacts_with DrugCentral:5350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.9']} DrugCentral uuid:63d366c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P13631 biolink:molecularly_interacts_with DrugCentral:5350 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trifarotene is agonist of Nuclear hormone receptor (Retinoic acid receptor gamma) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.11']} DrugCentral uuid:63d38fb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30939 biolink:molecularly_interacts_with DrugCentral:5351 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lasmiditan is agonist of GPCR (5-hydroxytryptamine receptor 1F) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.65']} DrugCentral uuid:63d3b9b6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0AD68 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan synthase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:63d3e29c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q07806 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:63d40cea-6b31-11ec-b3df-0242ac110002 UniProtKB:P02918 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:63d436a2-6b31-11ec-b3df-0242ac110002 UniProtKB:P02919 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:63d45f9c-6b31-11ec-b3df-0242ac110002 UniProtKB:G1C775 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.98']} DrugCentral uuid:63d4888c-6b31-11ec-b3df-0242ac110002 UniProtKB:A6T4V3 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 1B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.46']} DrugCentral uuid:63d4b23a-6b31-11ec-b3df-0242ac110002 UniProtKB:H4I819 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase MrdA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.66']} DrugCentral uuid:63d4db48-6b31-11ec-b3df-0242ac110002 UniProtKB:A0A0W8ASI8 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase MrdA) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.2']} DrugCentral uuid:63d5044c-6b31-11ec-b3df-0242ac110002 UniProtKB:A6T4M7 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.21']} DrugCentral uuid:63d52d50-6b31-11ec-b3df-0242ac110002 UniProtKB:G3XD46 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.22']} DrugCentral uuid:63d556b8-6b31-11ec-b3df-0242ac110002 UniProtKB:D0CCM7 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Peptidoglycan D,D-transpeptidase FtsI) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.17']} DrugCentral uuid:63d57fc6-6b31-11ec-b3df-0242ac110002 UniProtKB:A0A5E6DR09 biolink:molecularly_interacts_with DrugCentral:5352 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cefiderocol is inhibitor of Enzyme (Penicillin-binding protein 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.44']} DrugCentral uuid:63d5a8b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5353 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 zanubrutinib is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.52']} DrugCentral uuid:63d5d19c-6b31-11ec-b3df-0242ac110002 UniProtKB:P13196 biolink:molecularly_interacts_with DrugCentral:5354 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 givosiran is antisense inhibitor of RNA (aminolevulinate synthase1 (ALAS1) mRNA) DrugCentral uuid:63d5f7a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:5355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:63d620ac-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:5355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:63d6499c-6b31-11ec-b3df-0242ac110002 UniProtKB:P48169 biolink:molecularly_interacts_with DrugCentral:5355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.38']} DrugCentral uuid:63d67354-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16445 biolink:molecularly_interacts_with DrugCentral:5355 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cenobamate is allosteric modulator of Ion channel (Gamma-aminobutyric acid receptor subunit alpha-6) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.24']} DrugCentral uuid:63d69c30-6b31-11ec-b3df-0242ac110002 UniProtKB:P08684 biolink:molecularly_interacts_with DrugCentral:5356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxelotor is inhibitor of Enzyme (Cytochrome P450 3A4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.9']} DrugCentral uuid:63d6c53e-6b31-11ec-b3df-0242ac110002 UniProtKB:P10632 biolink:molecularly_interacts_with DrugCentral:5356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxelotor is inhibitor of Enzyme (Cytochrome P450 2C8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.1']} DrugCentral uuid:63d6ee1a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:5356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxelotor is inhibitor of Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.07']} DrugCentral uuid:63d717a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P69905 biolink:molecularly_interacts_with DrugCentral:5356 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 voxelotor is inhibitor of Transporter (hemoglobin subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.09']} DrugCentral uuid:63d74086-6b31-11ec-b3df-0242ac110002 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5357 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 golodirsen is antisense inhibitor of RNA (exon 53 of dystrophin pre-mRNA) DrugCentral uuid:63d76520-6b31-11ec-b3df-0242ac110002 UniProtKB:P08908 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (5-hydroxytryptamine receptor 1A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.83']} DrugCentral uuid:63d78e10-6b31-11ec-b3df-0242ac110002 UniProtKB:P28335 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (5-hydroxytryptamine receptor 2C) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.76']} DrugCentral uuid:63d7b8d6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35348 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (Alpha-1A adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.14']} DrugCentral uuid:63d7e1c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P21917 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (D(4) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.97']} DrugCentral uuid:63d80ab6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35368 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (Alpha-1B adrenergic receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.51']} DrugCentral uuid:63d833ce-6b31-11ec-b3df-0242ac110002 UniProtKB:P61169 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.5']} DrugCentral uuid:63d85d5e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21728 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone is antagonist of GPCR (D(1A) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.38']} DrugCentral uuid:63d88658-6b31-11ec-b3df-0242ac110002 UniProtKB:P31645 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone targets Transporter (Sodium-dependent serotonin transporter) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.48']} DrugCentral uuid:63d8aff2-6b31-11ec-b3df-0242ac110002 UniProtKB:P14416 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone is antagonist of GPCR (D(2) dopamine receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.49']} DrugCentral uuid:63d8da18-6b31-11ec-b3df-0242ac110002 UniProtKB:P28223 biolink:molecularly_interacts_with DrugCentral:5358 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumateperone is antagonist of GPCR (5-hydroxytryptamine receptor 2A) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.26']} DrugCentral uuid:63d90344-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99572 biolink:molecularly_interacts_with DrugCentral:5359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brilliant Blue G is antagonist of Ion channel (P2X purinoceptor 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:63d92c3e-6b31-11ec-b3df-0242ac110002 UniProtKB:P37840 biolink:molecularly_interacts_with DrugCentral:5359 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brilliant Blue G targets Transporter (Alpha-synuclein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:63d95506-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lemborexant targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:63d97e00-6b31-11ec-b3df-0242ac110002 UniProtKB:O43613 biolink:molecularly_interacts_with DrugCentral:5360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lemborexant is antagonist of GPCR (Orexin receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:63d9a8f8-6b31-11ec-b3df-0242ac110002 UniProtKB:O43614 biolink:molecularly_interacts_with DrugCentral:5360 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lemborexant is antagonist of GPCR (Orexin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.52']} DrugCentral uuid:63d9d21a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5361 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ubrogepant is antagonist of GPCR (Calcitonin gene-related peptide type 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.2']} DrugCentral uuid:63d9fb00-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9BQB4 biolink:molecularly_interacts_with DrugCentral:5362 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 romosozumab is binding agent of Glycoprotein (Sclerostin) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['11.7']} DrugCentral uuid:63da25c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:5363 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 brolucizumab is inhibitor of Secreted (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.8']} DrugCentral uuid:63da4eb6-6b31-11ec-b3df-0242ac110002 UniProtKB:O95390 biolink:molecularly_interacts_with DrugCentral:5364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luspatercept is binding agent of Cytokine (Growth/differentiation factor 11) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.13']} DrugCentral uuid:63da77a6-6b31-11ec-b3df-0242ac110002 UniProtKB:O14793 biolink:molecularly_interacts_with DrugCentral:5364 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 luspatercept is binding agent of Cytokine (Growth/differentiation factor 8) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.69']} DrugCentral uuid:63daa0a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P16109 biolink:molecularly_interacts_with DrugCentral:5365 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 crizanlizumab is inhibitor of Adhesion (P-selectin) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.59']} DrugCentral uuid:63dae86c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:63dae86c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:63dae86c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:63dae86c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:63dae86c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:63dae86c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:63dae86c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:63dae86c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:63dae86c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q3ZCM7 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Tubulin beta) DrugCentral uuid:63db6224-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96NY8 biolink:molecularly_interacts_with DrugCentral:5366 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enfortumab vedotin is binding agent of Tumour-associated antigen (Nectin-4) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.24']} DrugCentral uuid:63db8bdc-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab deruxtecan is binding agent of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.13']} DrugCentral uuid:63dbb4e0-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:5367 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trastuzumab deruxtecan is inhibitor of Enzyme (DNA topoisomerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.51']} DrugCentral uuid:63dbddc6-6b31-11ec-b3df-0242ac110002 UniProtKB:P60880 biolink:molecularly_interacts_with DrugCentral:5368 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 botulinum toxin type A is blocker of Cytosolic other (Synaptosomal-associated protein 25) DrugCentral uuid:63dc030a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9C0B1 biolink:molecularly_interacts_with DrugCentral:5371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxadustat targets Unclassified (Alpha-ketoglutarate-dependent dioxygenase FTO) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.01']} DrugCentral uuid:63dc2bf0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxadustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:63dc54f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxadustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:63dc7de4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5371 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 roxadustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.18']} DrugCentral uuid:63dca71a-6b31-11ec-b3df-0242ac110002 UniProtKB:P13569 biolink:molecularly_interacts_with DrugCentral:5372 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 elexacaftor targets Ion channel (Cystic fibrosis transmembrane conductance regulator) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.15']} DrugCentral uuid:63dccfce-6b31-11ec-b3df-0242ac110002 UniProtKB:P28593 biolink:molecularly_interacts_with DrugCentral:5375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cepharanthine targets Enzyme (Trypanothione reductase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.12']} DrugCentral uuid:63dcf8c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13131 biolink:molecularly_interacts_with DrugCentral:5375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cepharanthine is inhibitor of Kinase (5'-AMP-activated protein kinase catalytic subunit alpha-1) DrugCentral uuid:63dd1dd0-6b31-11ec-b3df-0242ac110002 UniProtKB:P19838 biolink:molecularly_interacts_with DrugCentral:5375 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cepharanthine is inhibitor of Cytosolic other (Nuclear factor NF-kappa-B p105 subunit) DrugCentral uuid:63dd4454-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DTD1 biolink:molecularly_interacts_with DrugCentral:5376 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remdesivir is inhibitor of Enzyme (Replicase polyprotein 1ab) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:63dd6d30-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UGN5 biolink:molecularly_interacts_with DrugCentral:5378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefuparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:63dd9620-6b31-11ec-b3df-0242ac110002 UniProtKB:P09874 biolink:molecularly_interacts_with DrugCentral:5378 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 mefuparib is inhibitor of Enzyme (Poly [ADP-ribose] polymerase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.49']} DrugCentral uuid:63ddbf24-6b31-11ec-b3df-0242ac110002 UniProtKB:P05532 biolink:molecularly_interacts_with DrugCentral:5379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avapritinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.66']} DrugCentral uuid:63dde8be-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avapritinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.57']} DrugCentral uuid:63de119a-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5379 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 avapritinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.62']} DrugCentral uuid:63de3a6c-6b31-11ec-b3df-0242ac110002 UniProtKB:O75530 biolink:molecularly_interacts_with DrugCentral:5380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazemetostat targets Unclassified (Polycomb protein EED) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:63de63c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92800 biolink:molecularly_interacts_with DrugCentral:5380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazemetostat is inhibitor of Enzyme (Histone-lysine N-methyltransferase EZH1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.41']} DrugCentral uuid:63de8cba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15910 biolink:molecularly_interacts_with DrugCentral:5380 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tazemetostat is inhibitor of Enzyme (Histone-lysine N-methyltransferase EZH2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:63deb5a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16602 biolink:molecularly_interacts_with DrugCentral:5381 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 rimegepant is antagonist of GPCR (Calcitonin gene-related peptide type 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.56']} DrugCentral uuid:63dedfee-6b31-11ec-b3df-0242ac110002 UniProtKB:P53396 biolink:molecularly_interacts_with DrugCentral:5382 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bempedoic acid is inhibitor of Enzyme (ATP-citrate synthase) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['5.69']} DrugCentral uuid:63df0b68-6b31-11ec-b3df-0242ac110002 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod targets GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:63df341c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod targets GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5']} DrugCentral uuid:63df5cf8-6b31-11ec-b3df-0242ac110002 UniProtKB:O95136 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod targets GPCR (Sphingosine 1-phosphate receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.02']} DrugCentral uuid:63df85ca-6b31-11ec-b3df-0242ac110002 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod is agonist of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['9.39']} DrugCentral uuid:63dfaf0a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:5383 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ozanimod is agonist of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:63dfd7c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11511 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat targets Enzyme (Aromatase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.07']} DrugCentral uuid:63e000cc-6b31-11ec-b3df-0242ac110002 UniProtKB:P15539 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.68']} DrugCentral uuid:63e02994-6b31-11ec-b3df-0242ac110002 UniProtKB:P15393 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat targets Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.3']} DrugCentral uuid:63e05306-6b31-11ec-b3df-0242ac110002 UniProtKB:P30099 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat targets Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.96']} DrugCentral uuid:63e07bd8-6b31-11ec-b3df-0242ac110002 UniProtKB:P19099 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat is inhibitor of Enzyme (Cytochrome P450 11B2, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.15']} DrugCentral uuid:63e0a4b4-6b31-11ec-b3df-0242ac110002 UniProtKB:P15538 biolink:molecularly_interacts_with DrugCentral:5384 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 osilodrostat is inhibitor of Enzyme (Cytochrome P450 11B1, mitochondrial) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.6']} DrugCentral uuid:63e0cd9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P28907 biolink:molecularly_interacts_with DrugCentral:5385 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 isatuximab is binding agent of Tumour-associated antigen (Lymphocyte differentiation antigen CD38) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:63e0f91e-6b31-11ec-b3df-0242ac110002 UniProtKB:P06881 biolink:molecularly_interacts_with DrugCentral:5386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eptinezumab is binding agent of GPCR (Calcitonin gene-related peptide 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.82']} DrugCentral uuid:63e12236-6b31-11ec-b3df-0242ac110002 UniProtKB:P10092 biolink:molecularly_interacts_with DrugCentral:5386 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 eptinezumab is binding agent of GPCR (Calcitonin gene-related peptide 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.24']} DrugCentral uuid:63e14b1c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08069 biolink:molecularly_interacts_with DrugCentral:5387 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 teprotumumab is antagonist of Kinase (Insulin-like growth factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:63e1745c-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selumetinib targets Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.66']} DrugCentral uuid:63e19de2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02750 biolink:molecularly_interacts_with DrugCentral:5388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selumetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:63e1c6e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P36507 biolink:molecularly_interacts_with DrugCentral:5388 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selumetinib is inhibitor of Kinase (Dual specificity mitogen-activated protein kinase kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.85']} DrugCentral uuid:63e1efb8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00533 biolink:molecularly_interacts_with DrugCentral:5389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tucatinib is inhibitor of Kinase (Epidermal growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.35']} DrugCentral uuid:63e21934-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tucatinib is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.5']} DrugCentral uuid:63e245e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tucatinib is inhibitor of Kinase (ERBB2/ERBB3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.16']} DrugCentral uuid:63e245e4-6b31-11ec-b3df-0242ac110002 UniProtKB:P21860 biolink:molecularly_interacts_with DrugCentral:5389 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tucatinib is inhibitor of Kinase (ERBB2/ERBB3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.16']} DrugCentral uuid:63e27ab4-6b31-11ec-b3df-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.52']} DrugCentral uuid:63e2a386-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:63e2ce42-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.4']} DrugCentral uuid:63e2f71e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5390 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pemigatinib is inhibitor of Kinase (Fibroblast growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.3']} DrugCentral uuid:63e31fe6-6b31-11ec-b3df-0242ac110002 UniProtKB:P55899 biolink:molecularly_interacts_with DrugCentral:5391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sacituzumab govitecan is antibody binding of Membrane receptor (IgG receptor FcRn large subunit p51) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.71']} DrugCentral uuid:63e34958-6b31-11ec-b3df-0242ac110002 UniProtKB:P11387 biolink:molecularly_interacts_with DrugCentral:5391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sacituzumab govitecan is binding agent of Enzyme (DNA topoisomerase 1) DrugCentral uuid:63e36e10-6b31-11ec-b3df-0242ac110002 UniProtKB:P09758 biolink:molecularly_interacts_with DrugCentral:5391 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sacituzumab govitecan is antibody binding of Tumour-associated antigen (Tumor-associated calcium signal transducer 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.58']} DrugCentral uuid:63e39700-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5392 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 capmatinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.88']} DrugCentral uuid:63e3bff0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96GD4 biolink:molecularly_interacts_with DrugCentral:5393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selpercatinib is inhibitor of Kinase (Aurora kinase B) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.1']} DrugCentral uuid:63e3e994-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5393 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 selpercatinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.76']} DrugCentral uuid:63e4127a-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:63e43b4c-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.47']} DrugCentral uuid:63e46428-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.91']} DrugCentral uuid:63e48e6c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.27']} DrugCentral uuid:63e4b75c-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:63e4e056-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5394 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ripretinib is inhibitor of Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.44']} DrugCentral uuid:63e50932-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:5395 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fluoroestradiol F 18 is binding agent of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['10.07']} DrugCentral uuid:63e53290-6b31-11ec-b3df-0242ac110002 UniProtKB:P10636 biolink:molecularly_interacts_with DrugCentral:5396 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 flortaucipir F 18 is binding agent of Structural (Microtubule-associated protein tau) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.24']} DrugCentral uuid:63e55b8a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inebilizumab is antibody binding of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.11']} DrugCentral uuid:63e585c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:5397 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inebilizumab is antibody binding of Surface antigen (B-lymphocyte antigen CD19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.8']} DrugCentral uuid:63e5b724-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:63e5b724-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:63e5b724-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-3/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.04']} DrugCentral uuid:63e60030-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:63e60030-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:63e60030-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; alpha-1/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.44']} DrugCentral uuid:63e649aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:63e649aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:63e649aa-6b31-11ec-b3df-0242ac110002 UniProtKB:P63138 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-2/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.18']} DrugCentral uuid:63e69428-6b31-11ec-b3df-0242ac110002 UniProtKB:P18508 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:63e69428-6b31-11ec-b3df-0242ac110002 UniProtKB:P18508 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:63e69428-6b31-11ec-b3df-0242ac110002 UniProtKB:P18508 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA A receptor alpha-5/beta-2/gamma-2) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.86']} DrugCentral uuid:63e6ebb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:63e6ebb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:63e6ebb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:63e6ebb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:63e6ebb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:63e6ebb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:63e6ebb2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99928 biolink:molecularly_interacts_with DrugCentral:5400 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 remimazolam is modulator of Ion channel (GABA-A receptor; benzodiazepine binding site) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.53']} DrugCentral uuid:63e75ca0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q75760 biolink:molecularly_interacts_with DrugCentral:5401 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fostemsavir is inhibitor of Viral envelope protein (Envelope glycoprotein gp160) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.08']} DrugCentral uuid:63e7859a-6b31-11ec-b3df-0242ac110002 UniProtKB:P32320 biolink:molecularly_interacts_with DrugCentral:5402 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 inqovi is inhibitor of Enzyme (Cytidine deaminase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.39']} DrugCentral uuid:63e7af16-6b31-11ec-b3df-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:63e7d7e8-6b31-11ec-b3df-0242ac110002 UniProtKB:P32246 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:63e800b0-6b31-11ec-b3df-0242ac110002 UniProtKB:P32246 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['4.8']} DrugCentral uuid:63e82a54-6b31-11ec-b3df-0242ac110002 UniProtKB:P51681 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:63e8531c-6b31-11ec-b3df-0242ac110002 UniProtKB:P51685 biolink:molecularly_interacts_with DrugCentral:5403 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 abametapir targets GPCR (C-C chemokine receptor type 8) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:63e87c02-6b31-11ec-b3df-0242ac110002 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:5404 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tafasitamab is antibody binding of Surface antigen (B-lymphocyte antigen CD19) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.39']} DrugCentral uuid:63e8a506-6b31-11ec-b3df-0242ac110002 UniProtKB:P55899 biolink:molecularly_interacts_with DrugCentral:5405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belantamab mafodotin is binding agent of Membrane receptor (IgG receptor FcRn large subunit p51) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.28']} DrugCentral uuid:63e8ce6e-6b31-11ec-b3df-0242ac110002 UniProtKB:P12314 biolink:molecularly_interacts_with DrugCentral:5405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belantamab mafodotin is binding agent of Membrane receptor (High affinity immunoglobulin gamma Fc receptor I) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.15']} DrugCentral uuid:63e8f79a-6b31-11ec-b3df-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belantamab mafodotin is binding agent of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.55']} DrugCentral uuid:63e921c0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02223 biolink:molecularly_interacts_with DrugCentral:5405 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 belantamab mafodotin is binding agent of Tumour-associated antigen (Tumor necrosis factor receptor superfamily member 17) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9']} DrugCentral uuid:63e94aba-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:63e97436-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:63e99d1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:63e9c5da-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.21']} DrugCentral uuid:63e9eec0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q13936 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Voltage-dependent L-type calcium channel subunit alpha-1C) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.44']} DrugCentral uuid:63ea1a1c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14524 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine targets Ion channel (Sodium channel protein type 5 subunit alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:63ea42f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P41146 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine is agonist of GPCR (Nociceptin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.4']} DrugCentral uuid:63ea6bc0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5406 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 oliceridine is agonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.22']} DrugCentral uuid:63ea94d8-6b31-11ec-b3df-0242ac110002 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5408 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 viltolarsen is binding agent of RNA (exon 53 of dystrophin pre-mRNA) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.33']} DrugCentral uuid:63eac282-6b31-11ec-b3df-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5409 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 satralizumab is antagonist of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:63eac282-6b31-11ec-b3df-0242ac110002 UniProtKB:P40189 biolink:molecularly_interacts_with DrugCentral:5409 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 satralizumab is antagonist of Membrane receptor (Interleukin-6 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:63eaf8c4-6b31-11ec-b3df-0242ac110002 UniProtKB:P10275 biolink:molecularly_interacts_with DrugCentral:5410 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 clascoterone is antagonist of Nuclear hormone receptor (Androgen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:63eb21d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P30874 biolink:molecularly_interacts_with DrugCentral:5411 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 copper dotatate Cu-64 is binding agent of GPCR (Somatostatin receptor type 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.69']} DrugCentral uuid:63eb4b26-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.46']} DrugCentral uuid:63eb7416-6b31-11ec-b3df-0242ac110002 UniProtKB:P09619 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Platelet-derived growth factor receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:63eb9d06-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:63ebc5f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.66']} DrugCentral uuid:63ebef9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04629 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (High affinity nerve growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:63ec1880-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.72']} DrugCentral uuid:63ec417a-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.96']} DrugCentral uuid:63ec6b8c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q08345 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Epithelial discoidin domain-containing receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.7']} DrugCentral uuid:63ec9490-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16288 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (NT-3 growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.05']} DrugCentral uuid:63ecbd80-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5412 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pralsetinib is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.39']} DrugCentral uuid:63ece742-6b31-11ec-b3df-0242ac110002 UniProtKB:P10912 biolink:molecularly_interacts_with DrugCentral:5413 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 somapacitan targets GPCR (Growth hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.04']} DrugCentral uuid:63ed108c-6b31-11ec-b3df-0242ac110002 UniProtKB:P01112 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Cytosolic other (GTPase HRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:63ed3990-6b31-11ec-b3df-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:63ed6276-6b31-11ec-b3df-0242ac110002 UniProtKB:P01111 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase NRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:63ed8b48-6b31-11ec-b3df-0242ac110002 UniProtKB:P01112 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase HRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:63edb53c-6b31-11ec-b3df-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.28']} DrugCentral uuid:63ede1f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:63ede1f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P49356 biolink:molecularly_interacts_with DrugCentral:5414 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lonafarnib is inhibitor of Enzyme (Protein farnesyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.72']} DrugCentral uuid:63ee16e4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UJM8 biolink:molecularly_interacts_with DrugCentral:5415 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 lumasiran is antisense inhibitor of RNA (Hydroxyacid oxidase 1 (HAO1) mRNA) DrugCentral uuid:63ee3b88-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:63ee64fa-6b31-11ec-b3df-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:63ee8dea-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:63eeb6da-6b31-11ec-b3df-0242ac110002 UniProtKB:P33032 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['6.37']} DrugCentral uuid:63eee092-6b31-11ec-b3df-0242ac110002 UniProtKB:P41968 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8']} DrugCentral uuid:63ef0982-6b31-11ec-b3df-0242ac110002 UniProtKB:Q01726 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocyte-stimulating hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.41']} DrugCentral uuid:63ef3286-6b31-11ec-b3df-0242ac110002 UniProtKB:P32245 biolink:molecularly_interacts_with DrugCentral:5416 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 setmelanotide is agonist of GPCR (Melanocortin receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.68']} DrugCentral uuid:63ef5b9e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q14973 biolink:molecularly_interacts_with DrugCentral:5417 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bulevirtide is inhibitor of Transporter (Sodium/bile acid cotransporter) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.49']} DrugCentral uuid:63ef90a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:63ef90a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:63ef90a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:63ef90a0-6b31-11ec-b3df-0242ac110002 UniProtKB:P01861 biolink:molecularly_interacts_with DrugCentral:5418 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imlifidase is inhibitor of Antibody (Immunoglobulin gamma (IgG), heavy chain) DrugCentral uuid:63efd52e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:63effe28-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:63f0274a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:63f05030-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:63f0790c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07333 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Macrophage colony-stimulating factor 1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.31']} DrugCentral uuid:63f0a2f6-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.56']} DrugCentral uuid:63f0cc9a-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.47']} DrugCentral uuid:63f0f576-6b31-11ec-b3df-0242ac110002 UniProtKB:Q12809 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib targets Ion channel (Potassium voltage-gated channel subfamily H member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.07']} DrugCentral uuid:63f11e52-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.09']} DrugCentral uuid:63f14878-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.55']} DrugCentral uuid:63f17532-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:63f19e40-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5419 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 filgotinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8']} DrugCentral uuid:63f1c776-6b31-11ec-b3df-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Secreted (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:63f1f0b6-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NWT6 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Enzyme (Hypoxia-inducible factor 1-alpha inhibitor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:63f219e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P15692 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Unclassified (Vascular endothelial growth factor A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.12']} DrugCentral uuid:63f242c8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8N543 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Unclassified (Prolyl 3-hydroxylase OGFOD1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.85']} DrugCentral uuid:63f26bae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NWT6 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat targets Unclassified (Hypoxia-inducible factor 1-alpha inhibitor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.54']} DrugCentral uuid:63f2955c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.81']} DrugCentral uuid:63f2be38-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.93']} DrugCentral uuid:63f2e728-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5420 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vadadustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.12']} DrugCentral uuid:63f31018-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5421 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daprodustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.46']} DrugCentral uuid:63f33aa2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5421 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daprodustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.14']} DrugCentral uuid:63f36388-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5421 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 daprodustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.26']} DrugCentral uuid:63f38c78-6b31-11ec-b3df-0242ac110002 UniProtKB:Q63016 biolink:molecularly_interacts_with DrugCentral:5422 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 borofalan (10B) is substrate of Transporter (L-type amino acid transporter 1) DrugCentral uuid:63f3b180-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:63f3dbc4-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:63f404c8-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride targets Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.21']} DrugCentral uuid:63f42e3a-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.43']} DrugCentral uuid:63f4572a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15303 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Receptor tyrosine-protein kinase erbB-4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.11']} DrugCentral uuid:63f480e2-6b31-11ec-b3df-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.22']} DrugCentral uuid:63f4aacc-6b31-11ec-b3df-0242ac110002 UniProtKB:P42680 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase Tec) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.32']} DrugCentral uuid:63f4d3c6-6b31-11ec-b3df-0242ac110002 UniProtKB:P42681 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase TXK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.04']} DrugCentral uuid:63f4fe00-6b31-11ec-b3df-0242ac110002 UniProtKB:P51451 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase Blk) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:63f52a10-6b31-11ec-b3df-0242ac110002 UniProtKB:Q06187 biolink:molecularly_interacts_with DrugCentral:5423 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirabrutinib hydrochloride is inhibitor of Kinase (Tyrosine-protein kinase BTK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.17']} DrugCentral uuid:63f553f0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NWZ3 biolink:molecularly_interacts_with DrugCentral:5424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tepotinib is inhibitor of Kinase (Interleukin-1 receptor-associated kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.21']} DrugCentral uuid:63f57ce0-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5424 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tepotinib is inhibitor of Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.77']} DrugCentral uuid:63f5a634-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UNQ0 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Transporter (ATP-binding cassette sub-family G member 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:63f5cf24-6b31-11ec-b3df-0242ac110002 UniProtKB:Q4U2R8 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Transporter (Solute carrier family 22 member 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.39']} DrugCentral uuid:63f5f814-6b31-11ec-b3df-0242ac110002 UniProtKB:Q8TCC7 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Transporter (Solute carrier family 22 member 8) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.88']} DrugCentral uuid:63f620f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P11712 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Enzyme (Cytochrome P450 2C9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.24']} DrugCentral uuid:63f64a94-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96S37 biolink:molecularly_interacts_with DrugCentral:5425 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dotinurad is inhibitor of Transporter (Solute carrier family 22 member 12) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.43']} DrugCentral uuid:63f6737a-6b31-11ec-b3df-0242ac110002 UniProtKB:O75116 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Rho-associated protein kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.58']} DrugCentral uuid:63f69c92-6b31-11ec-b3df-0242ac110002 UniProtKB:P52333 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.89']} DrugCentral uuid:63f6c596-6b31-11ec-b3df-0242ac110002 UniProtKB:P23458 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.55']} DrugCentral uuid:63f6f16a-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.58']} DrugCentral uuid:63f71a96-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5426 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 delgocitinib is inhibitor of Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.24']} DrugCentral uuid:63f74386-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9GZT9 biolink:molecularly_interacts_with DrugCentral:5427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enarodustat is inhibitor of Enzyme (Egl nine homolog 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.8']} DrugCentral uuid:63f76d0c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q96KS0 biolink:molecularly_interacts_with DrugCentral:5427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enarodustat is inhibitor of Enzyme (Egl nine homolog 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.21']} DrugCentral uuid:63f79610-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H6Z9 biolink:molecularly_interacts_with DrugCentral:5427 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 enarodustat is inhibitor of Enzyme (Egl nine homolog 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7']} DrugCentral uuid:63f7bf28-6b31-11ec-b3df-0242ac110002 UniProtKB:P20309 biolink:molecularly_interacts_with DrugCentral:5428 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sofpironium bromide is inhibitor of GPCR (Muscarinic acetylcholine receptor M3) DrugCentral uuid:63f7e4b2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07288 biolink:molecularly_interacts_with DrugCentral:5429 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 gallium (68Ga) gozetotide is binding agent of Surface antigen (Prostate-specific antigen) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.57']} DrugCentral uuid:63f81126-6b31-11ec-b3df-0242ac110002 UniProtKB:P03952 biolink:molecularly_interacts_with DrugCentral:5430 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 berotralstat is inhibitor of Enzyme (Plasma kallikrein) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.8']} DrugCentral uuid:63f83b9c-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirbanibulin is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:63f86482-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirbanibulin targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:63f88d72-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirbanibulin is inhibitor of Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['4.34']} DrugCentral uuid:63f8b9d2-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5431 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 tirbanibulin targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7']} DrugCentral uuid:63f8e600-6b31-11ec-b3df-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:5432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relugolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:63f90fae-6b31-11ec-b3df-0242ac110002 UniProtKB:P30969 biolink:molecularly_interacts_with DrugCentral:5432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relugolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.48']} DrugCentral uuid:63f938a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P30968 biolink:molecularly_interacts_with DrugCentral:5432 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 relugolix is antagonist of GPCR (Gonadotropin-releasing hormone receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9.92']} DrugCentral uuid:63f96206-6b31-11ec-b3df-0242ac110002 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5433 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ansuvimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.7']} DrugCentral uuid:63f98b0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P04626 biolink:molecularly_interacts_with DrugCentral:5434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 margetuximab is antagonist of Kinase (Receptor tyrosine-protein kinase erbB-2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.55']} DrugCentral uuid:63f9b422-6b31-11ec-b3df-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5434 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 margetuximab is antagonist of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['7.05']} DrugCentral uuid:63f9de16-6b31-11ec-b3df-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atoltivimab is antibody binding of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.64']} DrugCentral uuid:63fa0710-6b31-11ec-b3df-0242ac110002 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5436 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 atoltivimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.11']} DrugCentral uuid:63fa3014-6b31-11ec-b3df-0242ac110002 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5437 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 maftivimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.48']} DrugCentral uuid:63fa595e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08637 biolink:molecularly_interacts_with DrugCentral:5438 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 odesivimab is antibody binding of Membrane receptor (Low affinity immunoglobulin gamma Fc region receptor III-A) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.8']} DrugCentral uuid:63fa8320-6b31-11ec-b3df-0242ac110002 UniProtKB:P87666 biolink:molecularly_interacts_with DrugCentral:5438 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 odesivimab is antibody binding of Glycoprotein (Envelope glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.08']} DrugCentral uuid:63faac24-6b31-11ec-b3df-0242ac110002 UniProtKB:P20595 biolink:molecularly_interacts_with DrugCentral:5439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vericiguat is activator of Enzyme (Guanylate cyclase soluble subunit beta-1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6']} DrugCentral uuid:63fad500-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02153 biolink:molecularly_interacts_with DrugCentral:5439 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 vericiguat is activator of Enzyme (Guanylate cyclase soluble subunit beta-1) DrugCentral uuid:63faf9a4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabotegravir targets Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:63fb22ee-6b31-11ec-b3df-0242ac110002 UniProtKB:Q76353 biolink:molecularly_interacts_with DrugCentral:5440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabotegravir targets Unclassified (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:63fb4bfc-6b31-11ec-b3df-0242ac110002 UniProtKB:Q7ZJM1 biolink:molecularly_interacts_with DrugCentral:5440 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 cabotegravir is inhibitor of Enzyme (Integrase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.52']} DrugCentral uuid:63fb74ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P42336 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:63fb9e4a-6b31-11ec-b3df-0242ac110002 UniProtKB:P42338 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5']} DrugCentral uuid:63fbc7ee-6b31-11ec-b3df-0242ac110002 UniProtKB:P48736 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['5.85']} DrugCentral uuid:63fbf192-6b31-11ec-b3df-0242ac110002 UniProtKB:O00329 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.21']} DrugCentral uuid:63fc1ac8-6b31-11ec-b3df-0242ac110002 UniProtKB:P49674 biolink:molecularly_interacts_with DrugCentral:5441 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 umbralisib is inhibitor of Kinase (Casein kinase I isoform epsilon) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['6.74']} DrugCentral uuid:63fc43c2-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:63fc6df2-6b31-11ec-b3df-0242ac110002 UniProtKB:P06493 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:63fc97dc-6b31-11ec-b3df-0242ac110002 UniProtKB:P24941 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:63fcc0ae-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00535 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent-like kinase 5) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.83']} DrugCentral uuid:63fcea52-6b31-11ec-b3df-0242ac110002 UniProtKB:P50750 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 9) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.3']} DrugCentral uuid:63fd1324-6b31-11ec-b3df-0242ac110002 UniProtKB:P50613 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 7) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.33']} DrugCentral uuid:63fd3c14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H093 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (NUAK family SNF1-like kinase 2) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.15']} DrugCentral uuid:63fd64fa-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6ZWH5 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Serine/threonine-protein kinase Nek10) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.57']} DrugCentral uuid:63fd8e8a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q00534 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 6) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.4']} DrugCentral uuid:63fdb784-6b31-11ec-b3df-0242ac110002 UniProtKB:P11802 biolink:molecularly_interacts_with DrugCentral:5442 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 trilaciclib is inhibitor of Kinase (Cyclin-dependent kinase 4) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['9']} DrugCentral uuid:63fde09c-6b31-11ec-b3df-0242ac110002 UniProtKB:P11532 biolink:molecularly_interacts_with DrugCentral:5443 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 casimersen is antisense inhibitor of RNA (exon 53 of dystrophin pre-mRNA) DrugCentral uuid:63fe052c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9NZB8 biolink:molecularly_interacts_with DrugCentral:5444 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 fosdenopterin targets Enzyme (Molybdenum cofactor biosynthesis protein 1) DrugCentral uuid:63fe2a70-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9H228 biolink:molecularly_interacts_with DrugCentral:5446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 5) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['7.23']} DrugCentral uuid:63fe5338-6b31-11ec-b3df-0242ac110002 UniProtKB:O95977 biolink:molecularly_interacts_with DrugCentral:5446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 4) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:63fe7c14-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99500 biolink:molecularly_interacts_with DrugCentral:5446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['6.94']} DrugCentral uuid:63fea4f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P21453 biolink:molecularly_interacts_with DrugCentral:5446 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ponesimod is agonist of GPCR (Sphingosine 1-phosphate receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['8.13']} DrugCentral uuid:63fece26-6b31-11ec-b3df-0242ac110002 UniProtKB:P47871 biolink:molecularly_interacts_with DrugCentral:5447 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dasiglucagon is agonist of GPCR (Glucagon receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'EC50', 'has_quantitative_value': ['11']} DrugCentral uuid:63fef84c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9Y5C1 biolink:molecularly_interacts_with DrugCentral:5449 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 evinacumab is inhibitor of Secreted (Angiopoietin-related protein 3) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['9.04']} DrugCentral uuid:63ff2150-6b31-11ec-b3df-0242ac110002 UniProtKB:P03372 biolink:molecularly_interacts_with DrugCentral:5450 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estetrol is modulator of Nuclear hormone receptor (Estrogen receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.31']} DrugCentral uuid:63ff4a5e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q92731 biolink:molecularly_interacts_with DrugCentral:5450 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 estetrol is modulator of Nuclear hormone receptor (Estrogen receptor beta) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.72']} DrugCentral uuid:63ff7416-6b31-11ec-b3df-0242ac110002 UniProtKB:Q15116 biolink:molecularly_interacts_with DrugCentral:5451 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 dostarlimab is antibody binding of Membrane receptor (Programmed cell death protein 1) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.82']} DrugCentral uuid:63ff9d2e-6b31-11ec-b3df-0242ac110002 UniProtKB:P15391 biolink:molecularly_interacts_with DrugCentral:5452 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 loncastuximab tesirine is antibody binding of Surface antigen (B-lymphocyte antigen CD19) DrugCentral uuid:63ffc1f0-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5453 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 bamlanivimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.15']} DrugCentral uuid:63ffead6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5454 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 etesevimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['8.19']} DrugCentral uuid:640016e6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5455 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 casirivimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.34']} DrugCentral uuid:64003fd6-6b31-11ec-b3df-0242ac110002 UniProtKB:P0DTC2 biolink:molecularly_interacts_with DrugCentral:5456 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 imdevimab targets Glycoprotein (Spike glycoprotein) {'has_attribute_type': 'IAO:0000004', 'name': 'Kd', 'has_quantitative_value': ['10.33']} DrugCentral uuid:640068da-6b31-11ec-b3df-0242ac110002 UniProtKB:P01024 biolink:molecularly_interacts_with DrugCentral:5457 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 pegcetacoplan is inhibitor of Unclassified (Complement C3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.6']} DrugCentral uuid:640093a0-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04609 biolink:molecularly_interacts_with DrugCentral:5458 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 piflufolastat F-18 is binding agent of Enzyme (Glutamate carboxypeptidase 2) DrugCentral uuid:6400b81c-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:6400e0f8-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:640109c0-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:64013350-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:64015c22-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:640184f4-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:6401add0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6401d7ec-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:6402019a-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:64022a80-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:64025370-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:64027cb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:6402a582-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:6402ce54-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:6402f726-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:64032048-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:64034910-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:640371ec-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:64039abe-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:6403c57a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:6403ee56-6b31-11ec-b3df-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:64041728-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:640440b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:6404698a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:64049374-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:6404bc46-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:6404e59a-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:64050e80-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:64053752-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:6405601a-6b31-11ec-b3df-0242ac110002 UniProtKB:P35968 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Vascular endothelial growth factor receptor 2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.74']} DrugCentral uuid:64058af4-6b31-11ec-b3df-0242ac110002 UniProtKB:O60674 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase JAK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:6405b3bc-6b31-11ec-b3df-0242ac110002 UniProtKB:P00519 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase ABL1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.64']} DrugCentral uuid:6405ddb0-6b31-11ec-b3df-0242ac110002 UniProtKB:P06213 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Insulin receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:64060682-6b31-11ec-b3df-0242ac110002 UniProtKB:P06239 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lck) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.6']} DrugCentral uuid:640630a8-6b31-11ec-b3df-0242ac110002 UniProtKB:P06241 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Fyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.72']} DrugCentral uuid:6406597a-6b31-11ec-b3df-0242ac110002 UniProtKB:P07947 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Yes) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.96']} DrugCentral uuid:6406824c-6b31-11ec-b3df-0242ac110002 UniProtKB:P07948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase Lyn) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.52']} DrugCentral uuid:6406ab96-6b31-11ec-b3df-0242ac110002 UniProtKB:P07949 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase receptor Ret) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:6406d47c-6b31-11ec-b3df-0242ac110002 UniProtKB:P08581 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Hepatocyte growth factor receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:6406fd4e-6b31-11ec-b3df-0242ac110002 UniProtKB:P08922 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase ROS) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:64072620-6b31-11ec-b3df-0242ac110002 UniProtKB:P10721 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Mast/stem cell growth factor receptor Kit) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['6.12']} DrugCentral uuid:64075050-6b31-11ec-b3df-0242ac110002 UniProtKB:P12931 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Proto-oncogene tyrosine-protein kinase Src) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.53']} DrugCentral uuid:64077b5c-6b31-11ec-b3df-0242ac110002 UniProtKB:P15056 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Serine/threonine-protein kinase B-raf) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.38']} DrugCentral uuid:6407a42e-6b31-11ec-b3df-0242ac110002 UniProtKB:P16234 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Platelet-derived growth factor receptor alpha) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.57']} DrugCentral uuid:6407cd0a-6b31-11ec-b3df-0242ac110002 UniProtKB:P17948 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.82']} DrugCentral uuid:6407f690-6b31-11ec-b3df-0242ac110002 UniProtKB:P29597 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Non-receptor tyrosine-protein kinase TYK2) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.48']} DrugCentral uuid:64081f9e-6b31-11ec-b3df-0242ac110002 UniProtKB:P35916 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Vascular endothelial growth factor receptor 3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.68']} DrugCentral uuid:64084866-6b31-11ec-b3df-0242ac110002 UniProtKB:P36888 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Receptor-type tyrosine-protein kinase FLT3) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.49']} DrugCentral uuid:6408725a-6b31-11ec-b3df-0242ac110002 UniProtKB:P43405 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Tyrosine-protein kinase SYK) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.27']} DrugCentral uuid:64089ba4-6b31-11ec-b3df-0242ac110002 UniProtKB:P51813 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Cytoplasmic tyrosine-protein kinase BMX) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.47']} DrugCentral uuid:6408c48a-6b31-11ec-b3df-0242ac110002 UniProtKB:P54762 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Ephrin type-B receptor 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.52']} DrugCentral uuid:6408ed66-6b31-11ec-b3df-0242ac110002 UniProtKB:Q02763 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Angiopoietin-1 receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.69']} DrugCentral uuid:64091642-6b31-11ec-b3df-0242ac110002 UniProtKB:Q04912 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (Macrophage-stimulating protein receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.54']} DrugCentral uuid:640942e8-6b31-11ec-b3df-0242ac110002 UniProtKB:Q16620 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (BDNF/NT-3 growth factors receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.5']} DrugCentral uuid:64096d0e-6b31-11ec-b3df-0242ac110002 UniProtKB:Q99835 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets GPCR (Smoothened homolog) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['7.33']} DrugCentral uuid:640995f4-6b31-11ec-b3df-0242ac110002 UniProtKB:Q9UM73 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib targets Kinase (ALK tyrosine kinase receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['5.51']} DrugCentral uuid:6409bf7a-6b31-11ec-b3df-0242ac110002 UniProtKB:P22607 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 3) DrugCentral uuid:6409e41e-6b31-11ec-b3df-0242ac110002 UniProtKB:P21802 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 2) DrugCentral uuid:640a08b8-6b31-11ec-b3df-0242ac110002 UniProtKB:P22455 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 4) DrugCentral uuid:640a2d52-6b31-11ec-b3df-0242ac110002 UniProtKB:P11362 biolink:molecularly_interacts_with DrugCentral:5459 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 infigratinib is inhibitor of Kinase (Fibroblast growth factor receptor 1) DrugCentral uuid:640a5200-6b31-11ec-b3df-0242ac110002 UniProtKB:P35372 biolink:molecularly_interacts_with DrugCentral:5460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 samidorphan is antagonist of GPCR (Mu-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['10.28']} DrugCentral uuid:640a7b54-6b31-11ec-b3df-0242ac110002 UniProtKB:P41145 biolink:molecularly_interacts_with DrugCentral:5460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 samidorphan is partial agonist of GPCR (Kappa-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['9.64']} DrugCentral uuid:640aa444-6b31-11ec-b3df-0242ac110002 UniProtKB:P41143 biolink:molecularly_interacts_with DrugCentral:5460 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 samidorphan is partial agonist of GPCR (Delta-type opioid receptor) {'has_attribute_type': 'IAO:0000004', 'name': 'Ki', 'has_quantitative_value': ['8.59']} DrugCentral uuid:640acd52-6b31-11ec-b3df-0242ac110002 UniProtKB:P01116 biolink:molecularly_interacts_with DrugCentral:5461 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 sotorasib is inhibitor of Enzyme (GTPase KRas) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.03']} DrugCentral uuid:640af804-6b31-11ec-b3df-0242ac110002 UniProtKB:O13428 biolink:molecularly_interacts_with DrugCentral:5462 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrexafungerp is inhibitor of Enzyme (Beta-1,3-glucan synthase catalytic subunit 1) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.35']} DrugCentral uuid:640b21b2-6b31-11ec-b3df-0242ac110002 UniProtKB:Q6FTN8 biolink:molecularly_interacts_with DrugCentral:5462 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrexafungerp is inhibitor of Enzyme (1,3-Beta-D-glucan-UDP glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['7.83']} DrugCentral uuid:640b4a98-6b31-11ec-b3df-0242ac110002 UniProtKB:P87204 biolink:molecularly_interacts_with DrugCentral:5462 biolink:Association|biolink:DrugToGeneAssociation RO:0002436 ibrexafungerp is inhibitor of Enzyme (1,3-Beta-D-glucan-UDP glucosyltransferase) {'has_attribute_type': 'IAO:0000004', 'name': 'IC50', 'has_quantitative_value': ['8.97']} DrugCentral